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1

Hinshaw, Robert. "Carl Alfred (C. A.) Meier: April 19, 1905 - November 15, 1995." San Francisco Jung Institute Library Journal 14, no. 4 (1996): 77–78. http://dx.doi.org/10.1525/jung.1.1996.14.4.77.

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2

Ely, John J., Tony Zavaskis, and M. Lon Lammey. "Censored Data Analysis Reveals Effects of Age and Hepatitis C Infection on C-Reactive Protein Levels in Healthy Adult Chimpanzees (Pan troglodytes)." Journal of Biomarkers 2013 (February 27, 2013): 1–13. http://dx.doi.org/10.1155/2013/709740.

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C-reactive protein, a conserved acute-phase protein synthesized in the liver and involved in inflammation, infection, and tissue damage, is an informative biomarker for human cardiovascular disease. Out of 258 captive adult common chimpanzees (Pan troglodytes) assayed for CRP, 27.9% of the data were below the quantitation limit. Data were analyzed by the Kaplan-Meier method and results compared to other methods for handling censored data (including deletion, replacement, and imputation). Kaplan-Meier results demonstrated a modest age effect and a strong effect of HCV infection in reducing CRP
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3

Inglis, R., M. Pannike, A. Pannike, J. Windolf, and M. Lorenz. "Berechnung und grafische Darstellung der Produktmomentkorrelation nach KAPLAN-MEIER mit dem Personalcomputer - Programm KAPLGRAPH(c)." Biomedizinische Technik/Biomedical Engineering 35, s2 (1990): 166. http://dx.doi.org/10.1515/bmte.1990.35.s2.166.

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Bergoli, CD, LP Brondani, VF Wandscher, et al. "A Multicenter Randomized Double-blind Controlled Clinical Trial of Fiber Post Cementation Strategies." Operative Dentistry 43, no. 2 (2018): 128–35. http://dx.doi.org/10.2341/16-278-c.

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SUMMARY Objectives: The aim of this prospective randomized multicenter clinical trial was to evaluate the survival rate of glass fiber–reinforced posts cemented with self-adhesive or regular resin cements. Methods: The sample was comprised of 152 teeth randomized within two centers and in accordance with the adhesive strategies for RelyX U100/U200 (3M ESPE) or Single Bond and RelyX ARC (3M ESPE). The cementation procedures were standardized and performed by previously trained operators. The primary outcome evaluated was post debonding. A trained evaluator, one for each center, assessed all sub
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5

Halfter, Carl. "C. A. Meier, Der Traum als Medizin. Antike Inkubation und moderne Psychotherapie. Daimon Verlag, Zürich 1985." Gesnerus 42, no. 3-4 (1985): 517–18. http://dx.doi.org/10.1163/22977953-0420304030.

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6

Opalińska, Monika. "Samuel Meienreis and His Books From Leiden: Tracing the Provenance of the N-Psalter Fragments." Roczniki Humanistyczne 72, no. 5 Zeszyt specjalny (2024): 133–60. https://doi.org/10.18290/rh24725.7s.

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This paper presents the historical background and provenance research into fragments of a Latin Psalter with Old English glosses (N-Psalter), discovered in the bindings of early printed books from the collection of Samuel Meienreis, a Protestant theologian and bibliophile from Royal Prussia, who lived at the turn of the 16th and 17th centuries. Comparative and material analysis of the volumes with fragments in situ, currently held in the C. Norwid Library in Elbląg, indicates that they must have been bought in the Netherlands and bound in a local bookbinding workshop, most likely during Meienr
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Mohammadshahi, Jafar, Hassan Ghobadi, Golchin Matinfar, Mohammad Hossein Boskabady, and Mohammad Reza Aslani. "Role of Lipid Profile and Its Relative Ratios (Cholesterol/HDL-C, Triglyceride/HDL-C, LDL-C/HDL-C, WBC/HDL-C, and FBG/HDL-C) on Admission Predicts In-Hospital Mortality COVID-19." Journal of Lipids 2023 (March 6, 2023): 1–10. http://dx.doi.org/10.1155/2023/6329873.

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Background. Lipid profile and its related ratios such as total cholesterol (TC), low-density lipoprotein-cholesterol (LDL-C), triglyceride (TG), high-density lipoprotein-cholesterol (HDL-C), TG/HDL-C ratio, TC/HDL-C ratio, LDL-C/HDL-C ratio, white blood cell (WBC)/HDL-C ratio, and fasting blood glucose (FBG)/HDL-C ratio are valuable indicators that have been studied in various disorders to predict mortality. The present study was conducted with the aim of investigating the role of lipid profile ratios in predicting mortality in COVID-19 patients. Methods. At the beginning of hospitalization, l
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Samia, Rahman, Kumari Archana, and Mishra Atul. "Comparison of Repeated Bevacizumab Injections and Mitomycin C in Rotational Conjunctival Flap Surgery for Preventing Pterygium Recurrence." International Journal of Pharmaceutical and Clinical Research 16, no. 5 (2024): 3028–32. https://doi.org/10.5281/zenodo.13830723.

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<strong>Background</strong><strong>:</strong>&nbsp;Pterygium, a common ocular surface disorder, often necessitates surgical intervention due to its tendency for recurrence. Strategies to prevent recurrence, such as mitomycin C and more recently bevacizumab, have shown promise, but comparative effectiveness remains a topic of investigation. This study aimed to compare repeated bevacizumab injections versus mitomycin C in preventing pterygium recurrence following rotational conjunctival flap surgery.&nbsp;<strong>Methods</strong><strong>:</strong>&nbsp;A total of 200 participants were randomized
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9

Balasov, Maxim, Katarina Akhmetova, and Igor Chesnokov. "Drosophilamodel of Meier-Gorlin syndrome based on the mutation in a conserved C-Terminal domain of Orc6." American Journal of Medical Genetics Part A 167, no. 11 (2015): 2533–40. http://dx.doi.org/10.1002/ajmg.a.37214.

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10

Chiu, Vi Kien, and Adele Lerolle-Chiu. "Integrated survival analysis." Journal of Clinical Oncology 41, no. 16_suppl (2023): e14695-e14695. http://dx.doi.org/10.1200/jco.2023.41.16_suppl.e14695.

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e14695 Background: Clinical trial efficacy may be determined by the primary endpoint(s) of median progression free survival (mPFS) and/or median overall survival (mOS) from the Kaplan-Meier estimate, and secondary endpoints of overall response rate (ORR) and duration of response (DOR). In the treatment of metastatic cancers, single agent immunotherapy tends to have lower ORR and longer DOR in comparison to chemotherapy or targeted tyrosine kinase inhibitor therapy, which tends to have higher ORR and shorter DOR. This leads to intersecting or crossing Kaplan-Meier survival curves, which are har
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11

Nazarenko, Maria S., Iuliia V. Viakhireva, Mikhail Y. Skoblov, Elena V. Soloveva, Aleksei A. Sleptcov, and Ludmila P. Nazarenko. "Meier–Gorlin Syndrome: Clinical Misdiagnosis, Genetic Testing and Functional Analysis of ORC6 Mutations and the Development of a Prenatal Test." International Journal of Molecular Sciences 23, no. 16 (2022): 9234. http://dx.doi.org/10.3390/ijms23169234.

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Meier–Gorlin syndrome (MGS) is a rare genetic developmental disorder that causes primordial proportional dwarfism, microtia, the absence of or hypoplastic patellae and other skeletal anomalies. Skeletal symptoms overlapping with other syndromes make MGS difficult to diagnose clinically. We describe a 3-year-old boy with short stature, recurrent respiratory infections, short-rib dysplasia, tower head and facial dysmorphisms who was admitted to the Tomsk Genetic Clinic to verify a clinical diagnosis of Jeune syndrome. Clinical exome sequencing revealed two variants (compound heterozygosity) in t
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Kim, J.-H., J. Cho, Y. Lee, and B.-H. Cho. "The Survival of Class V Composite Restorations and Analysis of Marginal Discoloration." Operative Dentistry 42, no. 3 (2017): E93—E101. http://dx.doi.org/10.2341/16-186-c.

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SUMMARY The aims of this retrospective clinical study were to analyze the longevity of class V composite restorations and compare the results obtained from clinical and laboratory evaluation of marginal discoloration. A total of 186 restorations were evaluated with modified US Public Health Service criteria. Longevity and associated variables were analyzed with the Kaplan-Meier method and a Cox proportional hazard model. Restorations with marginal discoloration were additionally evaluated using digital photographs and epoxy resin replicas under a stereomicroscope. The mean survival time was 15
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13

Wong, J. B., K. Hino, F. Kurokawa, et al. "Validating a Markov Model of Treatment for Hepatitis C Virus-related Hepatocellular Carcinoma." Methods of Information in Medicine 47, no. 06 (2008): 529–40. http://dx.doi.org/10.3414/me9124.

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Summary Objective: We created and validated a Markov model to simulate the prognosis with treatment for HCV-related hepatocellular carcinoma (HCC) for assessment of cost-effectiveness for alternative treatments of HCC. Method: Markov state incorporated into the model consisted of the treatment as a surrogate for HCC stage and underlying liver function. Retrospective data of 793 patients from three university hospitals were used to determine Kaplan-Meier survival curves for each treatment and transition probabilities were derived from them. Results: There was substantial overlap in the 95% CIs
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Rho, Y.-J., C. Namgung, B.-H. Jin, B.-S. Lim, and B.-H. Cho. "Longevity of Direct Restorations in Stress-Bearing Posterior Cavities: A Retrospective Study." Operative Dentistry 38, no. 6 (2013): 572–82. http://dx.doi.org/10.2341/12-432-c.

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SUMMARYThe aims of this retrospective clinical study were to compare the longevities of direct posterior amalgam restorations (AMs) and resin composite restorations (RCs) that were subjected to occlusal stresses and to investigate variables predictive of their outcome. A total of 269 AMs and RCs filled in Class I and II cavities of posterior teeth were evaluated with Kaplan-Meier survival estimator and multivariate Cox proportional hazard model. Seventy-one retreated restorations were reviewed from dental records. The other 198 restorations still in use were evaluated according to modified US
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15

Munoz-Sanchez, ML, M. Bessadet, C. Lance, et al. "Survival Rate of CAD–CAM Endocrowns Performed by Undergraduate Students." Operative Dentistry 46, no. 5 (2021): 505–15. http://dx.doi.org/10.2341/20-126-c.

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SUMMARY Objectives: This study aimed to evaluate the success of computer-aided design–computer-aided manufacturing (CAD–CAM) endocrown restorations of endodontically treated teeth (ETT) performed by supervised undergraduate students. The study also intended to identify possible factors that may lead to failures. Methods and Materials: This observational open cohort study was based on clinical data from endocrown restorations performed by residents and undergraduate students in their 4th, 5th, and 6th year from July 2011 to May 2018. The presence of a tooth with an endocrown on the arch was the
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Rocha, AC, MM Suca Salas, AS Masotti, WLO da Rosa, CH Zanchi, and RG Lund. "A Randomized Double-blind Clinical Trial of Dentin Surface Treatments for Composite Restorations in Noncarious Cervical Lesions: A 36-month Evaluation." Operative Dentistry 44, no. 2 (2019): 114–26. http://dx.doi.org/10.2341/17-308-c.

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SUMMARY Objective: This randomized, double-blind clinical trial aimed to evaluate the influence of different dentin surface treatments in noncarious cervical lesions (NCCLs). Methods and Materials: Twenty-nine patients participated in this study. One hundred sixty-five NCCLs were selected and randomly assigned to three groups: G0 (control group) with phosphoric acid etching for 15 seconds; G1: phosphoric acid etching for 30 seconds; and G2: ultrasound probe applied for 30 seconds on the dentin surface. Class V composite resin restorations were performed (Z350, 3M ESPE, St Paul, MN, USA). The r
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17

Hemilä, Harri, and Elizabeth Chalker. "Bias against Vitamin C in Mainstream Medicine: Examples from Trials of Vitamin C for Infections." Life 12, no. 1 (2022): 62. http://dx.doi.org/10.3390/life12010062.

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Evidence has shown unambiguously that, in certain contexts, vitamin C is effective against the common cold. However, in mainstream medicine, the views on vitamin C and infections have been determined by eminence-based medicine rather than evidence-based medicine. The rejection of the demonstrated benefits of vitamin C is largely explained by three papers published in 1975—two published in JAMA and one in the American Journal of Medicine—all of which have been standard citations in textbooks of medicine and nutrition and in nutritional recommendations. Two of the papers were authored by Thomas
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18

Mohd, Shareef, Rathi Sudheer, Raj Baliyan Dheeraj, Usmani Yasmeen, Rijavan, and Raj Dhaval Nitin. "Comparison between a Single Dose Intravesical Instillation of Mitomycin-C versus gemcitabine Following Transurethral Resection of Bladder Tumor (TURBT) in Immediate Post-operative Period in Terms of Local Toxicity and Tumor recurrence: A prospective Study." International Journal of Pharmaceutical and Clinical Research 16, no. 12 (2024): 343–47. https://doi.org/10.5281/zenodo.14593169.

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<strong>Background:&nbsp;</strong>Bladder cancer is a common malignancy with a high risk of recurrence following transurethral resection of bladder tumors (TURBT). Intravesical chemotherapy, including agents like Gemcitabine and Mitomycin C, is widely used to reduce recurrence rates. However, there is limited comparative data on the efficacy and safety of these two agents in the postoperative setting.&nbsp;<strong>Aim and Objective:</strong>&nbsp;To evaluate and compare the postoperative recurrence rates and adverse events associated with intravesical Gemcitabine versus Mitomycin C in preventi
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19

Namgung, C., YJ Rho, BH Jin, BS Lim, and BH Cho. "A Retrospective Clinical Study of Cervical Restorations: Longevity and Failure-Prognostic Variables." Operative Dentistry 38, no. 4 (2013): 376–85. http://dx.doi.org/10.2341/11-416-c.

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SUMMARY The aim of this retrospective clinical study was to compare the longevity of cervical restorations between resin composite (RC) and glass ionomer (GI) and to investigate variables predictive of their outcome. The clinical performance of the two restorative materials in function was compared using the ratings of the modified United States Public Health Service (USPHS) criteria. A total of 479 cervical restorations were included in the study. Ninety-one already-replaced restorations were reviewed from dental records. The other 388 restorations still in function were evaluated according t
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Allende, José Ramón Grande, and Winfried Meier. "Novedades taxonómicas en Campanulaceae neotropicales I: dos nuevas especies de Centropogon C. Presl de Venezuela." Candollea 67, no. 2 (2012): 233–41. https://doi.org/10.15553/c2012v672a4.

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Allende, José Ramón Grande, Meier, Winfried (2012): Novedades taxonómicas en Campanulaceae neotropicales I: dos nuevas especies de Centropogon C. Presl de Venezuela. Candollea 67 (2): 233-241, DOI: 10.15553/c2012v672a4
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Kong, Lingxin, Qingtao Zhao, Zhaohui Han, et al. "Prognostic significance of TG/HDL-C and non-HDL-C/HDL-C ratios in patients with non-small cell lung cancer: a retrospective study." Journal of International Medical Research 50, no. 8 (2022): 030006052211172. http://dx.doi.org/10.1177/03000605221117211.

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Objective Lung cancer is a malignancy with high a mortality rate that threatens human health. This study is aimed to explore the correlation among the triglyceride/high-density lipoprotein ratio (TG/HDL-C), non-high-density lipoprotein/high-density lipoprotein ratio (non-HDL-C/HDL-C) and survival of patients with non-small cell lung cancer (NSCLC) undergoing video-associated thoracic surgery (VATS). Methods This retrospective study analyzed 284 patients with NSCLC who underwent VATS at Hebei General Hospital, Shijiazhuang, China. The time-dependent receiver operating characteristic curve was u
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Manojlović, Jelena, Tijana Vujasinović, Raković Nataša Todorović, John Greenman, Jelena Hranisavljević, and Marko Radulović. "Vascular endothelial growth factor (VEGF) -A, -C and VE-cadherin as potential biomarkers in early breast cancer patients." Pathology Research and Practice 252 (November 5, 2023): 154923. https://doi.org/10.1016/j.prp.2023.154923.

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Abstract <strong>Background:</strong> Vascular endothelial growth factor (VEGF)-A and -C, along with VE-cadherin (CDH5), play crucial roles in breast cancer progression. <strong>Aim:</strong> To investigate the association between intratumoral levels of VEGF-A, -C, and CDH5 and clinical outcomes in early-stage breast cancer. <strong>Patients and methods:</strong> 69 node-negative breast cancer patients with no prior systemic therapy were studied over a median follow-up of 144 months. mRNA levels were assessed using RT-qPCR. Prognostic performance was analyzed using Cox regression, Kaplan-Meier
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Wilson, P. J. "(C.) Meier The political art of Greek tragedy. Tr. A. Webber. Oxford: Polity P, 1993. Pp. vii + 238. £39.50." Journal of Hellenic Studies 115 (November 1995): 187–88. http://dx.doi.org/10.2307/631664.

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Wira Suastika, Ngakan Ketut, and Ketut Suega. "C-Reactive Protein: A Biomarker for Mortality Assessment in Cancer-Related Infections." International Journal of Health Sciences and Research 14, no. 10 (2024): 348–54. http://dx.doi.org/10.52403/ijhsr.20241036.

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Introduction: Infection is a common complication in cancer patients. Plasma C-reactive protein (CRP) levels can be used to assess disease activity in inflammatory and infectious conditions. This study aimed to determine the role of CRP level in predicting mortality in patients with cancer and infectious complications. Methods: This was a prospective study of solid and hematological cancer patients over 18 years of age undergoing hospital treatment. We used the Kaplan-Meier curve to obtain the median and overall survival. Cox regression analysis was used to determine the hazard ratio (HR) of CR
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Wang, Shu-Ming, Jiung Hsiun Liu, Che-Yi Chou, Chiu-Ching Huang, Chuen-Ming Shih, and Walter Chen. "Mortality in Hepatitis C-Positive Patients Treated with Peritoneal Dialysis." Peritoneal Dialysis International: Journal of the International Society for Peritoneal Dialysis 28, no. 2 (2008): 183–87. http://dx.doi.org/10.1177/089686080802800215.

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Objective The published mortality data for patients with hepatitis C virus (HCV) infection and being treated with peritoneal dialysis (PD) are not available. The aim of this study was to determine the mortality of HCV patients undergoing PD. Methods We retrospectively reviewed 538 PD patients in our hospital from 1996 to 2005. Of these patients, 75 (13.9%) were anti-HCV positive at the beginning of PD. We used Kaplan–Meier analysis to compare mortality between patients with and patients without HCV infection. The association between HCV infection and mortality was analyzed using multivariate C
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Hao, Bo, Xufeng Peng, Baochen Bi, Miaomei Yu, Chen Sang, and Zhen Chen. "Preoperative serum high-density lipoprotein cholesterol as a predictor of poor survival in patients with clear cell renal cell cancer." International Journal of Biological Markers 34, no. 2 (2019): 168–75. http://dx.doi.org/10.1177/1724600819831404.

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Purpose: Numerous studies have suggested that dyslipidemia is closely related to various cancers and the high-density lipoprotein cholesterol (HDL-C) levels are associated with the outcome of cancer patients. However, the predictive value of HDL-C in patients with renal cell carcinoma remains unclear. Our study aims to explore the relationship between the levels of serum HDL-C and the prognosis of renal cell carcinoma. Methods: A total of 308 patients diagnosed with clear cell renal cell carcinoma (CCRCC) who received surgical treatment were retrospectively enrolled in our study. The necessary
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AMIN, J., M. G. LAW, J. MICALLEF, et al. "Potential biases in estimates of hepatitis C RNA clearance in newly acquired hepatitis C infection among a cohort of injecting drug users." Epidemiology and Infection 135, no. 1 (2006): 144–50. http://dx.doi.org/10.1017/s0950268806006388.

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Estimates of hepatitis C virus (HCV) clearance following acute infection range from 14 to 46%. This wide range is likely to be due to the characteristics of the populations studied and analysis methods. This paper examines how differing definitions of clearance parameters affect estimates of viral clearance in a cohort of 85 injecting drug users with newly acquired HCV infection. Kaplan–Meier estimates of time to HCV clearance were determined using varying definitions of eligible cohort, viral clearance, date of infection and date of clearance. Based on which combinations of definitions were u
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28

Wegs, R. "German Women in the Nineteenth Century. John C. Fout (ed.) (New York: Holmes & Meier, 1984. xi plus 439 pp.)." Journal of Social History 20, no. 1 (1986): 208–10. http://dx.doi.org/10.1353/jsh/20.1.208.

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29

Henke, Lauren E., John D. Pfeifer, Thomas J. Baranski, Todd DeWees, and Perry W. Grigsby. "Long-term outcomes of follicular variant vs classic papillary thyroid carcinoma." Endocrine Connections 7, no. 12 (2018): 1226–35. http://dx.doi.org/10.1530/ec-18-0264.

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The majority of papillary thyroid carcinoma (PTC) cases comprise classic papillary (C-PTC) and follicular variant (FV-PTC) histologic sub-types. Historically, clinical equivalency was assumed, but recent data suggest C-PTC may have poorer outcomes. However, large single-institution series with long-term outcomes of C-PTC and FV-PTC, using modern pathologic criteria for FV-PTC, are needed. Our objective was to compare prevalence and impact of clinicopathologic factors, including BRAF mutation status, on long-term outcomes of C-PTC and FV-PTC. We hypothesized that patients with C-PTC would have
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Maryann Okafor, Ifeyinwa, Henshaw Uchechi Okoroiwu, and Christopher Ogar Ogar. "Diagnostic and prognostic value of c-MYC gene expression in hematological malignancies." African Health Sciences 23, no. 2 (2023): 265–73. http://dx.doi.org/10.4314/ahs.v23i2.30.

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Introduction: c-MYC plays vital role in regulation of cell proliferation and has been associated with tumorigenesis. This studyis aimed at assessing diagnostic and prognostic value of plasma c-MYC expression to aid in early diagnosis and prognosis ofhematological malignancies.&#x0D; Methods: Plasma c-MYC expression was determined by quantitative real time PCR using EVA Green chemistry and cluster ofdifferentiation markers performed via immunocytochemistry.&#x0D; Result: Plasma c-MYC was higher in subject with hematological malignancies (8.8 ± 1.1) when compared with apparently healthy controls
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Pan, Dikang, Julong Guo, Wenzhuo Meng, Jianming Guo, and Lianrui Guo. "Clinical features and surgical outcomes of childhood and adult Takayasu arteritis: A retrospective study." Vascular Investigation and Therapy 7, no. 1 (2024): 7–13. http://dx.doi.org/10.4103/vit.vit_19_24.

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Abstract: OBJECTIVE: Takayasu arteries (TAK) is a rare and unexplained inflammatory arterial disease that can occur in both children and adults. Our goal was to clarify the clinical features and surgical outcomes of aortitis in children and adults. METHODS: A retrospective cohort study was conducted on patients with TAK treated at tertiary care centers between 2012 and 2020. The American College of Rheumatology’s TAK criteria were used to select patients. Study results were reported using descriptive statistics and Kaplan–Meier methods. RESULTS: The cohort included 106 TAK patients with a medi
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Ott, Christine. "Franziska Meier, Besuch in der Hölle. Dantes Göttliche Komödie. Biographie eines Jahrtausendwerks, München, C. H. Beck 2021, 214 S." Deutsches Dante-Jahrbuch 97, no. 1 (2022): 158–62. http://dx.doi.org/10.1515/dante-2022-0011.

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Chen, Si-liang, Peng Hu, Zhi-peng Lin, and Jian-bo Zhao. "The Effect of Puncture Sites of Portal Vein in TIPS with ePTFE-Covered Stents on Postoperative Long-Term Clinical Efficacy." Gastroenterology Research and Practice 2019 (January 9, 2019): 1–11. http://dx.doi.org/10.1155/2019/2935498.

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Purpose. To evaluate the effect of puncture sites of the portal vein in transjugular intrahepatic portosystemic shunt (TIPS) on long-term clinical efficacy. Methods. A retrospective review was performed, including consecutive 171 patients who underwent TIPS with ePTFE-covered stents. All patients were divided into 3 groups according to the puncture site of the portal vein: intrahepatic bifurcation of the portal vein (group A, n=88), right branch of the portal vein (group B, n=48), and left branch of the portal vein (group C, n=35). The Kaplan-Meier analysis was performed to assess the effect o
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Agrelo, Ruben, Fernando Setien, Jesus Espada, et al. "Inactivation of the Lamin A/C Gene by CpG Island Promoter Hypermethylation in Hematologic Malignancies, and Its Association With Poor Survival in Nodal Diffuse Large B-Cell Lymphoma." Journal of Clinical Oncology 23, no. 17 (2005): 3940–47. http://dx.doi.org/10.1200/jco.2005.11.650.

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Purpose Lamins support the nuclear envelope and provide anchorage sites for chromatin, but they are also involved in DNA synthesis, transcription, and apoptosis. Although the lack of expression of A-type lamins in lymphoma and leukemia has been reported, the mechanism was unknown. We investigated the possible role of CpG island hypermethylation in lamin A/C silencing and its prognostic relevance. Patients and Methods The promoter CpG island methylation status of the lamin A/C gene, encoding the A-type lamins, was analyzed by bisulfite genomic sequencing and methylation-specific polymerase chai
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Crees, Zachary D., Caleb Shearrow, Leo Lin, et al. "EGFR/c-Met and mTOR signaling are predictors of survival in non-small cell lung cancer." Therapeutic Advances in Medical Oncology 12 (January 2020): 175883592095373. http://dx.doi.org/10.1177/1758835920953731.

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Background: EGFR/c-Met activation/amplification and co-expression, mTOR upregulation/activation, and Akt/Wnt signaling upregulation have been individually associated with more aggressive disease and characterized as potential prognostic markers for lung cancer patients. Methods: Tumors obtained from 109 participants with stage I–IV non-small cell lung cancer (NSCLC) were studied for EGFR/c-Met co-localization as well as for total and active forms of EGFR, c-Met, mTOR, S6K, beta-catenin, and Axin2. Slides were graded by two independent blinded pathologists using a validated scoring system. Prot
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Schmeusser, Benjamin, Adil Ali, Dattatraya H. Patil, et al. "Creatinine to cystatin C ratio and mortality in renal cell carcinoma." Journal of Clinical Oncology 41, no. 6_suppl (2023): 697. http://dx.doi.org/10.1200/jco.2023.41.6_suppl.697.

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697 Background: Creatinine and cystatin C are routinely used to assess renal function. Given creatinine originates from skeletal muscle and cystatin C is produced by nucleated cells, a creatinine to cystatin C ratio (Cr/Cys-C) may positively correlate with muscle mass. Low Cr/Cys-C has also been associated with decreased overall survival (OS) in cancer, including in a combined cohort of genitourinary malignancies. Furthermore, elevated cystatin c has been associated with shorter OS and recurrence free survival (RFS) in renal cell carcinoma (RCC). Cr/Cys-C may be a simple and affordable tool to
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Shah, Rahman, Saifullah Khan Khalil, Umar Aleem, Falak Naz, Naimat Ullah та Najeeb Ullah. "Association of Interleukin-28b- Rs8099917 with Response to Treatment with Interferon Α-2b & Ribavirin in C. Hepatitis C pts". Pakistan Journal of Medical and Health Sciences 16, № 3 (2022): 28–29. http://dx.doi.org/10.53350/pjmhs2216328.

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Aim: To reassess the high specificity of alkaline phosphatase as a serum tumor marker in patients with osteosarcoma Study type: Retrospective cohort study Study place and duration: Department of Orthopedics, DHQ Hospital Gujranwala from January 2013 to June 2021 Methods: The medical record of 140 osteosarcoma patients were reviewed retrospectively, who received treatment for osteosarcoma during January 2015 and June 2021. According to clinical factors at diagnosis, the difference in prevalence of increased ALP was assessed using Fisher`s extract test and χ2 test. In the groups with normal and
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Choque Aliaga, Osman. "Reseña de Heinrich Meier, Nietzsches Vermächtnis: Ecce homo und Der Antichrist. Zwei Bücher über Natur und Politik. München: C. H. Beck, 2019." Revista de humanidades (Santiago. En línea), no. 49 (January 29, 2024): 485–89. http://dx.doi.org/10.53382/issn.2452-445x.790.

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Fasano, Serena, Luciana Pierro, Ilenia Pantano, Michele Iudici, and Gabriele Valentini. "Longterm Hydroxychloroquine Therapy and Low-dose Aspirin May Have an Additive Effectiveness in the Primary Prevention of Cardiovascular Events in Patients with Systemic Lupus Erythematosus." Journal of Rheumatology 44, no. 7 (2017): 1032–38. http://dx.doi.org/10.3899/jrheum.161351.

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Objective.Systemic lupus erythematosus (SLE) is associated with an increased risk of cardiovascular disease (CVD). Thromboprophylaxis with low-dose aspirin (ASA) and hydroxychloroquine (HCQ) seems promising in SLE. We investigated the effects of HCQ cumulative dosages (c-HCQ) and the possible synergistic efficacy of ASA and HCQ in preventing a first CV event (CVE) in patients with SLE.Methods.Patients consecutively admitted to our center who, at admission, satisfied the 1997 American College of Rheumatology and/or 2012 Systemic Lupus Collaborating Clinics classification criteria for SLE, and h
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Du, Zhenguang, Qianru He, Xiaodan Xing, et al. "VEGFR-C mutation serves as a potential negative predictor for immunotherapy in metastatic melanoma." Journal of Clinical Oncology 40, no. 16_suppl (2022): e21593-e21593. http://dx.doi.org/10.1200/jco.2022.40.16_suppl.e21593.

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e21593 Background: Immune checkpoint blockade has shown significant promise as an anticancer treatment and anti–CTLA-4 treatment prolongs overall survival in patients with melanoma. Vascular endothelial growth factor-C (VEGF-C), a member of the VEGF gene family, has been characterised as a prime mediator of lymphangiogenesis and angiogenic growth factors that promote the growth and metastasis of neoplasms. Previous studies provided evidence that VEGF-C correlated with poorer survival in melanoma. We aimed to determine the association of VEGF-C mutations with melanoma survival to immune checkpo
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Huang, Qiao, and Chong Tian. "Visualizing Time-Varying Effect in Survival Analysis: 5 Complementary Plots to Kaplan-Meier Curve." Oxidative Medicine and Cellular Longevity 2022 (March 29, 2022): 1–12. http://dx.doi.org/10.1155/2022/3934901.

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Background. Kaplan-Meier (KM) curve has been widely used in the field of oxidative medicine and cellular longevity. However, time-varying effect might be presented in KM curve and cannot be intuitively observed. Complementary plots might promote clear insights in time-varying effect from KM curve. Methods. Three KM curves were identified from published randomized control trials: (a) curves diverged immediately; (b) intersected curves with statistical significance; and (c) intersected curves without statistical significance. We reconstructed individual patient data, and plotted 5 complementary
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Alqahtani, Abdulsalam, Sourav Bhattacharjee, Abdulrahman Almopti, Chunhui Li, and Ghulam Nabi. "Radiomics-Based Computed Tomography Urogram Approach for the Prediction of Survival and Recurrence in Upper Urinary Tract Urothelial Carcinoma." Cancers 16, no. 18 (2024): 3119. http://dx.doi.org/10.3390/cancers16183119.

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Upper tract urothelial carcinoma (UTUC) is a rare and aggressive malignancy with a poor prognosis. The accurate prediction of survival and recurrence in UTUC is crucial for effective risk stratification and guiding therapeutic decisions. Models combining radiomics and clinicopathological data features derived from computed tomographic urograms (CTUs) can be a way to predict survival and recurrence in UTUC. Thus, preoperative CTUs and clinical data were analyzed from 106 UTUC patients who underwent radical nephroureterectomy. Radiomics features were extracted from segmented tumors, and the Leas
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Chou, Che-Yi, I.-Kuan Wang, Jiung-Hsiun Liu, Hsin-Hung Lin, Shu-Ming Wang, and Chiu-Ching Huang. "Comparing Survival between Peritoneal Dialysis and Hemodialysis Treatment in Esrd Patients with Chronic Hepatitis C Infection." Peritoneal Dialysis International: Journal of the International Society for Peritoneal Dialysis 30, no. 1 (2010): 86–90. http://dx.doi.org/10.1177/089686081003000101.

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Objective End-stage renal disease (ESRD) patients with hepatitis C virus (HCV) infection are associated with an increasing mortality risk on hemodialysis (HD) and peritoneal dialysis (PD). The aim of this study was to compare patient survival between HCV-positive patients undergoing PD versus HD. Methods We reviewed 78 PD and 78 HD patients with chronic hepatitis C infection in China Medical University Hospital from 1996 to 2006. The HD patients were selected using the propensity score matching method. Kaplan–Meier analysis with log-rank test was used to compare patient survival between patien
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Sclafani, Francesco, David Gonzalez, David Cunningham, et al. "Relationship of RAS and TP53 predictive value for cetuximab (C) benefit: Results of the EXPERT-C trial." Journal of Clinical Oncology 32, no. 3_suppl (2014): 447. http://dx.doi.org/10.1200/jco.2014.32.3_suppl.447.

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447 Background: We previously reported that TP53 status may predict C benefit in patients with locally advanced rectal cancer treated with neoadjuvant chemotherapy and chemoradiotherapy (CRT) and this effect appeared to be independent of KRAS. Recent studies indicate that NRAS mutations and KRAS mutations beyond exons 2-3 may also preclude benefit from anti-EGFRs. We analyzed whether the predictive value of TP53 in EXPERT-C was independent of RAS. Methods: 164 patients received 4 cycles of CAPOX followed by CRT, surgery, and 4 cycles of adjuvant CAPOX (n=81) or the same regimen plus C (CAPOX-C
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Fang, Shenying, Yuling Wang, Dawen Sui, et al. "C-Reactive Protein As a Marker of Melanoma Progression." Journal of Clinical Oncology 33, no. 12 (2015): 1389–96. http://dx.doi.org/10.1200/jco.2014.58.0209.

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Purpose To investigate the association between blood levels of C-reactive protein (CRP) in patients with melanoma and overall survival (OS), melanoma-specific survival (MSS), and disease-free survival. Patients and Methods Two independent sets of plasma samples from a total of 1,144 patients with melanoma (587 initial and 557 confirmatory) were available for CRP determination. Kaplan-Meier method and Cox regression were used to evaluate the relationship between CRP and clinical outcome. Among 115 patients who underwent sequential blood draws, we evaluated the relationship between change in dis
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Saadat, Mostafa, Samane Safaie, and Iraj Saadat. "Genetic Polymorphism of C-262T Catalase and Susceptibility to Schizophrenia." Open Access Macedonian Journal of Medical Sciences 2, no. 1 (2014): 74–77. http://dx.doi.org/10.3889/oamjms.2014.013.

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Background: Catalase (CAT, OMIM: 115500) plays an integral role in the primary defence against oxidative stress. The T allele of the C-262T CAT polymorphism (rs1001179) is associated with lower activity of CAT. Here we investigated whether polymorphism of C-266T CAT was associated with susceptibility to schizophrenia.Methods: The present study was performed on 363 (267 males, 96 females) in-patients with schizophrenia diagnosis, and a total of 363 (266 males, 97 females) healthy controls. The C-262T CAT genotypes were determined using RFLP-PCR method.Results: Although the association between g
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Talbot, Ross. "Agriculture and the State: Market Processes and Bureaucracy. By E. C. PasourJr,. New York: Holmes & Meier, 1990. 258p. $39.95 cloth, $19.95 paper." American Political Science Review 85, no. 1 (1991): 300–302. http://dx.doi.org/10.2307/1962928.

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Roncin, Jean-Yves, and Françoise Launay. "Comment on “The EUV dayglow at high spectral resolution” by M. D. Morrison, C. W. Bowers, P. D. Feldman, and R. R. Meier." Journal of Geophysical Research: Space Physics 96, A2 (1991): 1881. http://dx.doi.org/10.1029/90ja02449.

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Jiang, Q., Z. Wang, S. Zhang, X. Liu, and B. Fu. "Performance of Bonded Lithium Disilicate Partial-coverage Crowns in the Restoration of Endodontically Treated Posterior Teeth: An Up to Seven-Year Retrospective Study." Operative Dentistry, July 8, 2024. http://dx.doi.org/10.2341/23-107-c.

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SUMMARY Objectives: To evaluate the clinical performance of adhesively bonded lithium disilicate glass-ceramic (LDG) partial-coverage crowns in restoring posterior endodontically treated teeth (ETT). Methods and Materials: A total of 121 morphologically compromised posterior ETT were restored with LDG partial-coverage crowns between October 2015 and January 2018. The restorations were fabricated in the laboratory or at the chairside. Two adhesive systems and resin cements were used to cement the restorations. Tooth and restoration survival rates were calculated. The restorations were evaluated
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Thein, Alexander. "Caesar, Cicero, and Augustus (on C. Meier, Die Ohnmacht des allmächtigen Dictators Caesar. Drei biographische Skizzen)." Histos 10 (June 1, 2016). http://dx.doi.org/10.29173/histos355.

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