Relevant bibliographies by topics / Meiotic Chromosome Condensation

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  1. Journal articles
  2. Dissertations / Theses
  3. Book chapters

Academic literature on the topic 'Meiotic Chromosome Condensation'

Author: Grafiati
Published: 4 June 2021
Last updated: 7 September 2023

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Journal articles on the topic "Meiotic Chromosome Condensation"

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Clemons, Amy M., Heather M. Brockway, Yizhi Yin, et al. "akirin is required for diakinesis bivalent structure and synaptonemal complex disassembly at meiotic prophase I." Molecular Biology of the Cell 24, no. 7 (2013): 1053–67. http://dx.doi.org/10.1091/mbc.e12-11-0841.

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During meiosis, evolutionarily conserved mechanisms regulate chromosome remodeling, leading to the formation of a tight bivalent structure. This bivalent, a linked pair of homologous chromosomes, is essential for proper chromosome segregation in meiosis. The formation of a tight bivalent involves chromosome condensation and restructuring around the crossover. The synaptonemal complex (SC), which mediates homologous chromosome association before crossover formation, disassembles concurrently with increased condensation during bivalent remodeling. Both chromosome condensation and SC disassembly
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Chan, Raymond C., Aaron F. Severson, and Barbara J. Meyer. "Condensin restructures chromosomes in preparation for meiotic divisions." Journal of Cell Biology 167, no. 4 (2004): 613–25. http://dx.doi.org/10.1083/jcb.200408061.

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The production of haploid gametes from diploid germ cells requires two rounds of meiotic chromosome segregation after one round of replication. Accurate meiotic chromosome segregation involves the remodeling of each pair of homologous chromosomes around the site of crossover into a highly condensed and ordered structure. We showed that condensin, the protein complex needed for mitotic chromosome compaction, restructures chromosomes during meiosis in Caenorhabditis elegans. In particular, condensin promotes both meiotic chromosome condensation after crossover recombination and the remodeling of
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Rhee, K., and D. J. Wolgemuth. "The NIMA-related kinase 2, Nek2, is expressed in specific stages of the meiotic cell cycle and associates with meiotic chromosomes." Development 124, no. 11 (1997): 2167–77. http://dx.doi.org/10.1242/dev.124.11.2167.

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The Aspergillus nimA gene encodes a Ser/Thr protein kinase which is required for mitosis, in addition to Cdc2, and which has been suggested to have a role in chromosomal condensation. In this study, we isolated a potential murine homologue of nimA, Nek2, which was shown to be expressed most abundantly in the testis of the adult tissues examined. Its expression in the testis was restricted to the germ cells, with highest levels detected in spermatocytes at pachytene and diplotene stages. Immunohistochemical analysis revealed that Nek2 localized to nuclei, exhibiting a non-uniform distribution w
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Yu, Hong-Guo, and Douglas E. Koshland. "Meiotic condensin is required for proper chromosome compaction, SC assembly, and resolution of recombination-dependent chromosome linkages." Journal of Cell Biology 163, no. 5 (2003): 937–47. http://dx.doi.org/10.1083/jcb.200308027.

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Condensin is an evolutionarily conserved protein complex that helps mediate chromosome condensation and segregation in mitotic cells. Here, we show that condensin has two activities that contribute to meiotic chromosome condensation in Saccharomyces cerevisiae. One activity, common to mitosis, helps mediate axial length compaction. A second activity promotes chromosome individualization with the help of Red1 and Hop1, two meiotic specific components of axial elements. Like Red1 and Hop1, condensin is also required for efficient homologue pairing and proper processing of double strand breaks. C
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Loidl, J., F. Klein, and H. Scherthan. "Homologous pairing is reduced but not abolished in asynaptic mutants of yeast." Journal of Cell Biology 125, no. 6 (1994): 1191–200. http://dx.doi.org/10.1083/jcb.125.6.1191.

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In situ hybridization was used to examine chromosome behavior at meiotic prophase in the rad50S, hop1, rad50, and spo11 mutants of Saccharomyces cerevisiae, which are defective in chromosome synapsis and meiotic recombination. Painting of chromosomes I and III revealed that chromosome condensation and pairing are reduced in these mutants. However, there is some residual pairing in meiosis, suggesting that homologue recognition is independent of synaptonemal complex formation and recombination. Association of homologues was observed in the rad50, rad50S, and spo11 mutants, which are defective i
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Balicky, Eric M., Matthew W. Endres, Cary Lai, and Sharon E. Bickel. "Meiotic Cohesion Requires Accumulation of ORD on Chromosomes before Condensation." Molecular Biology of the Cell 13, no. 11 (2002): 3890–900. http://dx.doi.org/10.1091/mbc.e02-06-0332.

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Cohesion between sister chromatids is a prerequisite for accurate chromosome segregation during mitosis and meiosis. To allow chromosome condensation during prophase, the connections that hold sister chromatids together must be maintained but still permit extensive chromatin compaction. In Drosophila, null mutations in the orientation disruptor (ord) gene lead to meiotic nondisjunction in males and females because cohesion is absent by the time that sister kinetochores make stable microtubule attachments. We provide evidence that ORD is concentrated within the extrachromosomal domains of the n
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Howard-Till, Rachel, and Josef Loidl. "Condensins promote chromosome individualization and segregation during mitosis, meiosis, and amitosis in Tetrahymena thermophila." Molecular Biology of the Cell 29, no. 4 (2018): 466–78. http://dx.doi.org/10.1091/mbc.e17-07-0451.

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Condensin is a protein complex with diverse functions in chromatin packaging and chromosome condensation and segregation. We studied condensin in the evolutionarily distant protist model Tetrahymena, which features noncanonical nuclear organization and divisions. In Tetrahymena, the germline and soma are partitioned into two different nuclei within a single cell. Consistent with their functional specializations in sexual reproduction and gene expression, condensins of the germline nucleus and the polyploid somatic nucleus are composed of different subunits. Mitosis and meiosis of the germline
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Hartsuiker, Edgar, Jürg Bähler, and Jürg Kohli. "The Role of Topoisomerase II in Meiotic Chromosome Condensation and Segregation in Schizosaccharomyces pombe." Molecular Biology of the Cell 9, no. 10 (1998): 2739–50. http://dx.doi.org/10.1091/mbc.9.10.2739.

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Topoisomerase II is able to break and rejoin double-strand DNA. It controls the topological state and forms and resolves knots and catenanes. Not much is known about the relation between the chromosome segregation and condensation defects as found in yeasttop2 mutants and the role of topoisomerase II in meiosis. We studied meiosis in a heat-sensitive top2mutant of Schizosaccharomyces pombe. Topoisomerase II is not required until shortly before meiosis I. The enzyme is necessary for condensation shortly before the first meiotic division but not for early meiotic prophase condensation. DNA repli
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Cao, Zubing, Tengteng Xu, Xu Tong, et al. "HASPIN kinase mediates histone deacetylation to regulate oocyte meiotic maturation in pigs." Reproduction 157, no. 6 (2019): 501–10. http://dx.doi.org/10.1530/rep-18-0447.

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HASPIN kinase-catalyzed phosphorylation of histone H3 on threonine 3 (H3T3p) directs the activity and localization of chromosomal passenger complex (CPC) and spindle assembly checkpoint (SAC) to regulate chromosome condensation and segregation in both mitosis and meiosis. However, the function of HASPIN kinase in the meiotic maturation of porcine oocytes is not yet known. Here, we found that HASPIN mRNA is constantly expressed in porcine oocyte maturation and subsequent early embryo development. H3T3p is highly enriched on chromosomes at germinal vesicle breakdown (GVBD) stage and thereafter m
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Di Agostino, Silvia, Pellegrino Rossi, Raffaele Geremia, and Claudio Sette. "The MAPK pathway triggers activation of Nek2 during chromosome condensation in mouse spermatocytes." Development 129, no. 7 (2002): 1715–27. http://dx.doi.org/10.1242/dev.129.7.1715.

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Chromosome condensation during the G2/M progression of mouse pachytene spermatocytes induced by the phosphatase inhibitor okadaic acid (OA) requires the activation of the MAPK Erk1. In many cell systems, p90Rsks are the main effectors of Erk1/2 function. We have identified p90Rsk2 as the isoform that is specifically expressed in mouse spermatocytes and have shown that it is activated during the OA-triggered meiotic G2/M progression. By using the MEK inhibitor U0126, we have demonstrated that activation of p90Rsk2 during meiotic progression requires activation of the MAPK pathway. Immunofluores
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Dissertations / Theses on the topic "Meiotic Chromosome Condensation"

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Nikalayevich, Elvira. "Meiotic spindle organization and chromosome condensation in Drosophila oocytes." Thesis, University of Edinburgh, 2014. http://hdl.handle.net/1842/17908.

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Errors in chromosome segregation during the first division of female meiosis are very common in humans and result in aneuploidy leading to reproduction problems. Chromosome segregation depends on the formation and function of the meiotic spindle as well as the structure of chromosomes, which need to condense to be able to orient and segregate properly. It is important to understand the mechanisms underlying the female meiotic spindle function and chromosome condensation to gain insight into female fertility problems. The female meiotic spindle assembles without centrosomes, so the mechanisms e
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Mitra, Sayantan. "Arabidopsis Cohesin proteins: WAPL, CTF7 and PHD finger proteins: MMDL1, MMDL2 are essential for proper meiosis, gamete development and plant growth." Miami University / OhioLINK, 2017. http://rave.ohiolink.edu/etdc/view?acc_num=miami1517605898967702.

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Khan, Krishnendu. "Structure-Function Relationships of Saccharomyces Cerevisiae Meiosis Specific Hop 1 Protein : Implications for Chromosome Condensation, Pairing and Spore Formation." Thesis, 2012. http://etd.iisc.ac.in/handle/2005/3246.

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Meiosis is a specialized type of cell division essential for the production of four normal haploid gametes. In early prophase I of meiosis, the intimate synapsis between homologous chromosomes, and the formation of chiasmata, is facilitated by a proteinaceous structure known as the synaptonemal complex (SC). Ultrastructural analysis of germ cells of a number of organisms has disclosed that SC is a specialized tripartite structure composed of two lateral elements, one on each homolog, and a central element, which, in turn, are linked by transverse elements. Genetic studies have revealed that de
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Khan, Krishnendu. "Structure-Function Relationships of Saccharomyces Cerevisiae Meiosis Specific Hop 1 Protein : Implications for Chromosome Condensation, Pairing and Spore Formation." Thesis, 2012. http://hdl.handle.net/2005/3246.

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Meiosis is a specialized type of cell division essential for the production of four normal haploid gametes. In early prophase I of meiosis, the intimate synapsis between homologous chromosomes, and the formation of chiasmata, is facilitated by a proteinaceous structure known as the synaptonemal complex (SC). Ultrastructural analysis of germ cells of a number of organisms has disclosed that SC is a specialized tripartite structure composed of two lateral elements, one on each homolog, and a central element, which, in turn, are linked by transverse elements. Genetic studies have revealed that de
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Barra, Lucia. "Profilo trascrizionale dei microsporociti del mutante meiotic chromosome condensation di Arabidopsis mediante laser microdissection microarray (LMM)." Tesi di dottorato, 2008. http://www.fedoa.unina.it/3971/1/tesi_dottorato_lucia_barra.pdf.

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I meccanismi molecolari che regolano la meiosi nelle piante sono ancora poco noti. Finora sono stati isolati circa cinquanta geni meiotici vegetali soprattutto tramite mutanti inserzionali di Arabidopsis thaliana con approcci di “forward” e “reverse genetics”, in quest’ultimo caso utilizzando strategie comparative con organismi modello. Studi recenti evidenziano un coinvolgimento delle modificazioni istoniche post-traduzionali, tra cui l’acetilazione, nel processo meiotico di diversi organismi che non includono finora alcuna specie vegetale. La ricerca svolta durante il dottorato ha riguardato
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Book chapters on the topic "Meiotic Chromosome Condensation"

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NISHIMOTO, TAKEHARU, KOZO AJIRO, FRANCES M. DAVIS, et al. "Mitosis-Specific Protein Phosphorylation Associated with Premature Chromosome Condensation in a ts Cell Cycle Mutant." In Molecular Regulation of Nuclear Events in Mitosis and Meiosis. Elsevier, 1987. http://dx.doi.org/10.1016/b978-0-12-625115-9.50014-0.

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Journal articles
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