Academic literature on the topic 'Melanoma, Cancer, Tomato, Polyphenols'

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Journal articles on the topic "Melanoma, Cancer, Tomato, Polyphenols"

1

Pop, Teodora Daria, and Zorita Diaconeasa. "Recent Advances in Phenolic Metabolites and Skin Cancer." International Journal of Molecular Sciences 22, no. 18 (2021): 9707. http://dx.doi.org/10.3390/ijms22189707.

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Skin cancer represents any tumor development from the cutaneous structures within the epidermis, dermis or subcutaneous tissue, and is considered to be the most prevalent type of cancer. Compared to other types of cancer, skin cancer is proven to have a positive growth rate of prevalence and mortality. There are available various treatments, including chemotherapy, immunotherapy, radiotherapy and targeted therapy, but because of the multidrug resistance development, a low success has been registered. By this, the importance of studying naturally occurring compounds that are both safe and effec
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2

Isacescu, Ecaterina, Paul Chiroi, Oana Zanoaga, et al. "Melanoma Cellular Signaling Transduction Pathways Targeted by Polyphenols Action Mechanisms." Antioxidants 12, no. 2 (2023): 407. http://dx.doi.org/10.3390/antiox12020407.

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Melanoma is the most aggressive type of skin cancer. Although different anti-melanoma treatments are available, their efficacy is still improvable, and the number of deaths continues to increase worldwide. A promising source of antitumor agents could be presented by polyphenols—natural plant-based compounds. Over the past decades, many studies have described multiple anticancer effects of polyphenols in melanoma, presenting their potential interactions with targeted molecules from different signaling pathways. However, to our knowledge, there is no comprehensive review on polyphenols-regulated
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3

Martí, Raúl, Salvador Roselló, and Jaime Cebolla-Cornejo. "Tomato as a Source of Carotenoids and Polyphenols Targeted to Cancer Prevention." Cancers 8, no. 6 (2016): 58. http://dx.doi.org/10.3390/cancers8060058.

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4

Chen, Xianjin, Lili Chang, Yan Qu, Jinning Liang, Waishu Jin, and Xiujuan Xia. "Tea polyphenols inhibit the proliferation, migration, and invasion of melanoma cells through the down-regulation of TLR4." International Journal of Immunopathology and Pharmacology 31 (January 1, 2018): 039463201773953. http://dx.doi.org/10.1177/0394632017739531.

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Melanoma is the most common skin cancer and malignant melanoma which can cause skin cancer-related deaths. Toll-like receptor 4 (TLR4) had been reported to play an important role in melanoma, and tea polyphenol (TP) is regarded as an anticancer substance. However, the relationship between TP and TLR4 in melanoma is not well explored. Therefore, our aim is to figure out how TP has an influence on melanoma. Melanoma cell lines (B16F10 and A375) were treated with TP and lipopolysaccharides (LPS). Western blot assay was used to examine TLR4 expression, and MTT assay was conducted to assess prolife
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5

Helyes, Lajos, Zoltán Pék, Sára Brandt, and Andrea Lugasi. "Analysis of Antioxidant Compounds and Hydroxymethylfurfural in Processing Tomato Cultivars." HortTechnology 16, no. 4 (2006): 615–19. http://dx.doi.org/10.21273/horttech.16.4.0615.

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Tomato (Lycopersicon esculentum) fruit is an important source of antioxidants, which are important in the prevention of many cancer types and cardiovascular diseases. In ripe tomato fruit, one of the most significant antioxidant compounds is lycopene. In this study, effects of the cultivars and the environmental conditions on the lycopene content were investigated. Temperature effect was characterized by calculating growing degree-day (GDD). Relationships among lycopene, total polyphenols, organic acid, and total antioxidant status (TAS) were analyzed. A variation of more than 30% was found am
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6

Prakash, Monica D., Lily Stojanovska, Jack Feehan, et al. "Anti-cancer effects of polyphenol-rich sugarcane extract." PLOS ONE 16, no. 3 (2021): e0247492. http://dx.doi.org/10.1371/journal.pone.0247492.

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Plant polyphenols have an array of health benefits primarily thought to be related to their high content of anti-oxidants. These are commonly undervalued and knowledge of their biological properties have grown exponentially in the last decade. Polyphenol-rich sugarcane extract (PRSE), a natural extract from sugar cane, is marketed as high in anti-oxidants and polyphenols, but its anti-cancer activity has not been reported previously. We show that, PRSE exerts anti-cancer properties on a range of cancer cells including human (LIM2045) and mouse (MC38, CT26) colon cancer cells lines; human lung
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7

Fortes, C., S. Mastroeni, F. Melchi, et al. "FC4 Foods rich in polyphenols and N-3 fatty acids decrease cutaneous melanoma risk." Melanoma Research 20 (June 2010): e30. http://dx.doi.org/10.1097/01.cmr.0000382806.14581.52.

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8

Obrador, Elena, Rosario Salvador-Palmer, Ali Jihad-Jebbar, et al. "Pterostilbene in Cancer Therapy." Antioxidants 10, no. 3 (2021): 492. http://dx.doi.org/10.3390/antiox10030492.

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Natural polyphenols are organic chemicals which contain phenol units in their structures and possess antitumor properties. However, a key problem is their short half-life and low bioavailability under in vivo conditions. Pterostilbene (3,5-dimethoxy-4′-hydroxystilbene; PT) is a phytoalexin originally isolated from the heartwood of red sandalwood. As recently reported by our group, PT was shown to be effective in the treatment of melanoma. Counterintuitively, PT is not effective (cytotoxic) against melanoma in vitro, and only under in vivo conditions does PT display its anticancer activity. Thi
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9

Knez Marevci, Maša, Sašo Bjelić, Barbara Dariš, Željko Knez, and Maja Leitgeb. "The Influence of Extracts from Common Houseleek (Sempervivum tectorum) on the Metabolic Activity of Human Melanoma Cells WM-266-4." Processes 9, no. 9 (2021): 1549. http://dx.doi.org/10.3390/pr9091549.

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Human melanoma cells are known as one of the most aggressive cancer cells, and consequently, melanoma is one of the most incurable cancer diseases. There is intense activity in research and development of potential medicines for malignant diseases, including alternative forms of remedies. Therefore, the purpose of our work was testing extracts from the common houseleek (Sempervivum tectorum) grown in Slovenia to establish its impact on human melanoma cells. Namely, we wanted to verify if the extracts inhibit growth of malignant cells and their metabolic activity. Soxhlet, cold solvent, ultraso
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10

Szabo, Katalin, Laura Mitrea, Lavinia Florina Călinoiu, et al. "Natural Polyphenol Recovery from Apple-, Cereal-, and Tomato-Processing By-Products and Related Health-Promoting Properties." Molecules 27, no. 22 (2022): 7977. http://dx.doi.org/10.3390/molecules27227977.

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Polyphenols of plant origin are a broad family of secondary metabolites that range from basic phenolic acids to more complex compounds such as stilbenes, flavonoids, and tannins, all of which have several phenol units in their structure. Considerable health benefits, such as having prebiotic potential and cardio-protective and weight control effects, have been linked to diets based on polyphenol-enriched foods and plant-based products, indicating the potential role of these substances in the prevention or treatment of numerous pathologies. The most representative phenolic compounds in apple po
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