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Relevant bibliographies by topics / Meldonium dihydrate

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Journal articles

Academic literature on the topic 'Meldonium dihydrate'

Author: Grafiati

Published: 4 June 2025

Last updated: 1 August 2025

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Journal articles on the topic "Meldonium dihydrate"

1

Аnastasiia, Donchenko, Nahorna Natalia, and Vasyuk Svitlana. "Development and validation of spectrophotometric method for the determination of meldonium dihydrate in dosage forms." ScienceRise: Pharmaceutical Science, no. 4(14) (August 31, 2018): 23–27. https://doi.org/10.15587/2519-4852.2018.141397.

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<strong>Aim</strong><strong>.</strong><strong> </strong>Spectrophotometry is one of the most widely used methods in the pharmaceutical analysis. The main advantages of this absorption method are the highly sensitive, cost-effective and available to quality control laboratories for dosage forms. However, there is a need to find new analytical reagents. Therefore, the aim of the present work was investigation and development of spectrophotometric method based on reaction with p-chloranil for the determination of meldonium dihydrate in dosage forms. <strong>Methods. </strong>In the stud

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2

Sinkova, M. N., L. K. Isakov, T. V. Pepelyaeva, N. I. Tarasov, A. T. Teplyakov, and F. Yu Mukharlyamov. "Impact myocardial cytoprotection and inotropic stimulation at the annual prognosis in patients with myocardial infarction lifting segment ST, complicated heart failure." CardioSomatics 6, no. 2 (2015): 30–34. http://dx.doi.org/10.26442/cs45131.

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The article analyzes the effectiveness and safety of treatment cytoprotectant meldonium dihydrate and inotropic stimulator of levosimendan on an annual prognosis in patients with myocardial infarction complicated by acute heart failure II-III class Killip, subjected to percutaneous transluminal coronary angioplasty.

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3

Horyn, Mariana, Marjan Piponski, Olha Poliak, Nataliia Shulyak, Marta Sulyma, and Liliya Logoyda. "Development of the spectrophotometric method for the determination of meldonium in capsules by using alizarine." ScienceRise: Pharmaceutical Science, no. 1(47) (February 29, 2024): 12–19. http://dx.doi.org/10.15587/2519-4852.2024.299165.

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The aim of the work was to develop a simple, rapid, economic spectrophotometric method for the determination of meldonium in capsules based on the reaction with alizarin. Materials and methods. Analytical equipment: double-beam UV-visible spectrophotometer Shimadzu UV 1800 (Japan), a pair of 1 cm matched quartz cells, software UV-Probe 2.62, laboratory electronic balance RAD WAG AS 200/C, pH-meter И-160МИ. Pharmacopoeial standard sample (CRS) of meldonium dihydrate (Sigma-Aldrich, (≥ 98 %, HPLC)), alizarin (Synbias), capsules Metamax (Darnytsia) 250 mg, Vasopro (Farmak) 500 mg, Mildronat

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4

Kordiyak, О. Y., K. A. Moroz, Z. M. Honta, O. M. Nemesh, and I. V. Shylivskyi. "MINERAL COMPOSITION OF MANDIBULAR BONE TISSUE IN SIMULATED PERIODONTITIS DURING METABOLIC ACIDOSIS." Актуальні проблеми сучасної медицини: Вісник Української медичної стоматологічної академії 24, no. 1 (2024): 94–99. http://dx.doi.org/10.31718/2077-1096.24.1.94.

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Destructive changes in the mandibular cancellous bone tissue determine the severity of periodontal diseases and affect their treatment outcomes. The imbalance between macro- and microelements leads to structural and functional changes in the spongy bone tissue of the lower jaw, and when being combined with the inflammatory process in the soft tissues of the periodontium leads to the tooth loss. Mineral elements deposited in the bones are included in the body buffer systems and are able to influence the metabolic processes of the macroorganism by mobilizing them into the bloodstream. The

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5

Horyn, Mariana, Marjan Piponski, Tetiana Zaremba, et al. "Application of salts of chaotropic anions in the development of hplc methods for the determination of meldonium in dosage forms." ScienceRise: Pharmaceutical Science, no. 1(41) (February 28, 2023): 14–22. http://dx.doi.org/10.15587/2519-4852.2023.274469.

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The aim of the work was to create an approach for the development of HPLC methods for the determination of meldonium in dosage forms with the usage of salts of chaotropic anions in mobile phases. Material and methods. Analytical equipment: Shimadzu UPLC system LC-40 PDA; Shimadzu Nexera-i LC-2040C 3D-Plus, controlled by software Lab Solution version 5.97, electronic laboratory balance RAD WAG AS 200/C, pH-meter I-160MI. Meldonium dihydrate (purity 99.3 %) was purchased from Sigma-Aldrich (Switzerland), and Vasopro capsules 500 mg were purchased from a local pharmacy. Chromatographic cond

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6

Donchenko, Аnastasiia, Natalia Nahorna, and Svitlana Vasyuk. "Development and validation of spectrophotometric method for the determination of meldonium dihydrate in dosage forms." ScienceRise: Pharmaceutical Science, no. 4 (14) (August 31, 2018): 23–27. http://dx.doi.org/10.15587/2519-4852.2018.141397.

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7

Mariana, Horyn, Piponski Marjan, Zaremba Tetiana, et al. "Application of salts of chaotropic anions in the development of hplc methods for the determination of meldonium in dosage forms." ScienceRise: Pharmaceutical Science, no. 1(41) (February 28, 2023): 14–22. https://doi.org/10.15587/2519-4852.2023.274469.

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<strong>The aim of the work</strong> was to create an approach for the development of HPLC methods for the determination of meldonium in dosage forms with the usage of salts of chaotropic anions in mobile phases. <strong>Material and methods. </strong>Analytical equipment: Shimadzu UPLC system LC-40 PDA; Shimadzu Nexera-i LC-2040C 3D-Plus, controlled by software Lab Solution version 5.97, electronic laboratory balance RAD WAG AS 200/C, pH-meter I-160MI. Meldonium dihydrate (purity 99.3 %) was purchased from Sigma-Aldrich (Switzerland), and Vasopro capsules 500 mg were purchased from

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8

Neibergs, Miks, Elīna Strade, Vizma Nikolajeva, Igors Susinskis, Dzintars Rozitis, and Daina Kalnina. "Application of Bioaugmentation to Improve Pharmaceutical Wastewater Treatment Efficiency." Key Engineering Materials 800 (April 2019): 122–31. http://dx.doi.org/10.4028/www.scientific.net/kem.800.122.

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Ecological harm and human health risks caused by environmental pollution with active pharmaceutical ingredients (API) nowadays is recognised as issue of growing concern. Widespread presence of human and veterinary API in aquatic environment clearly indicates persistence and low removal efficiency of these compounds at conventional pharmaceutical and municipal wastewater treatment plants (WWTP). Bioaugmentation of activated sludge systems with specialized microorganisms could be a powerful and environmentally friendly tool to enhance the removal efficiency of recalcitrant API. Selection of inoc

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9

Shishkova, V. N., L. A. Kapustina, and K. E. Imamgayazova. "A current view on the prospects for the pharmaceutical therapy in neurorehabilitation after stroke." Meditsinskiy sovet = Medical Council, no. 11 (July 6, 2022): 8–17. http://dx.doi.org/10.21518/2079-701x-2022-16-11-8-17.

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Introduction. Given due regard to the urgency of the issue of pharmaceutical support in neurorehabilitation after stroke, an open multicenter study was designed and conducted.Aim. To evaluate the efficacy and safety of therapy with Brainmax®, which is an original combination of two drugs: ethylmethylhydroxypyridine succinate (EMHPS) (100 mg/ml) and meldonium dihydrate (100 mg/ml) in the form of a solution for intravenous and intramuscular injections in patients with ischemic stroke in the acute and early recovery period.Materials and methods. The study included 60 patients aged 18 to 80 years

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10

Pogorelov, V. V., I. Y. Bagmut та V. I. Zhukov. "ЕНДОТЕЛІАЛЬНІ Й ІМУНОЛОГІЧНІ ЗМІНИ ПРИ КОМПРЕСІЙНО-ІШЕМІЧНІЙ РАДИКУЛОМІЄЛОПАТІЇ ТА ЇХ ЕНЕРГЕТИЧНА КОРЕКЦІЯ". Вісник наукових досліджень, № 2 (11 липня 2018). http://dx.doi.org/10.11603/2415-8798.2018.2.8924.

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The pathological process of compression-ischemic radiculomyelopathy (CIRMP ) is accompanied by high energy costs. Therefore, topical is the use of drugs that improve energy metabolism in hypoxic conditions.The aim of the study – to investigate the features of the immuno-inflammatory process in CIRMP under the influence of meldonium.Materials and Methods. The parameters of 45 patients with CIRMP were investigated. All patients received conventional therapy. Patients of the group 1 (26 patients) received meldonium additionally, and in the group 2 (the main one – 19 patients) included "capicor".

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