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Journal articles on the topic 'Melonidae'
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1
Gros, Roger. "INTERVIEW WITH MELONIE JOHNSON." Gaming Law Review 24, no. 8 (2020): 528–31. http://dx.doi.org/10.1089/glr2.2020.2485.
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DARYONO, BUDI SETIADI, APRILIA SUFI SUBIASTUTI, ARVITA FATMADANNI, and DIAN SARTIKA. "Phenotypic and genetic stability of new Indonesian melon cultivar (Cucumis melo L. ‘Melonia’) based on ISSR markers." Biodiversitas Journal of Biological Diversity 20, no. 4 (2019): 1069–75. http://dx.doi.org/10.13057/biodiv/d200419.
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Abstract. Daryono BS, Subiastuti AS, Fatmadanni A, Sartika D. 2019. Phenotypic and genetic stability of new Indonesian melon cultivar (Cucumis melo L. ‘Melonia’) based on ISSR markers. Biodiversitas 20: 1069-1075. Cucumis melo L. ‘Melonia’ was new Indonesian melon cultivars produced by segregation of Meloni cultivar. The Meloni cultivar has a yellowish-skinned color, orange flesh fruit, and sweet taste. The stability of phenotype and genotype characters of this new cultivars were assessed using 27 morphological traits and 4 ISSR primers, respectively. Phenotype characters in F2 and F3 populations have been stable on 25 of 27 morphological traits used, except in weight of seed cavity and color of skin fruit. The 4 ISSR markers were produced 41 fragments, contained 28 monomorphic DNA bands and 13 polymorphic DNA bands. All of DNA bands were scored and used for genetic similarity analysis using MVSP 3.1A Program. The highest genetic variation was produced by UBC-808 primer with a polymorphic percentage of 38.46%. All of ‘Melonia’ populations were clustered together with 100% similarity percentage. Compared to other cultivars, ‘Melonia’ had high similarity with ‘Meloni’ in 87.8%, meanwhile, ‘Melonia’ and Meloni cultivars had relationship with Melona at a similarity value of 70.7%.
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Barkov, Andrei Y., Gennadiy I. Shvedov, Roberta L. Flemming, Anna Vymazalová, and Robert F. Martin. "Melonite from Kingash and Kuskanak, Eastern Sayans, Russia, and the extent of Bi-for-Te substitution in melonite and synthetic Ni(Te,Bi)2–x." Mineralogical Magazine 81, no. 3 (2017): 695–705. http://dx.doi.org/10.1180/minmag.2016.080.119.
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AbstractWe describe occurrences of palladoan melonite in intimate intergrowths with cobaltite-gersdorffite from the Neoproterozoic dunite-wehrlite-gabbro complexes of Kingash and Kuskanak, Eastern Sayans, Russia. The observed compositional trends of melonite are consistent with the overallvariations examined on the basis of numerous literature sources. The levels of Bi in NiTe2 are normally limited to ≤0.25 Bi atoms per formula unit (apfu), under natural conditions. Greater levels (≤0.5 Bi apfu) are associated with the (Pd + Pt) enrichment in the palladoanvarieties. The telluride–sulfarsenide intergrowths probably formed at Kingash and Kuskanak late in the crystallization history of the ore zones, from microdroplets of residual melt rich in semimetals (Te, Bi, As) and noble metals (Pd and Ag), below the solidus of the enclosing gabbroicrocks and within a narrow range of temperatures (500–550°C). On the basis of our observations made on specimens of melonite and synthetic Ni(Te,Bi)2–x (x = 0.6), we infer that the limit of incorporation of Bi into a melonitetype phase is ≤0.5 Bi apfu.
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Thomas, Melonie. "GCSEs to BSc -- where to begin?" Biochemist 28, no. 5 (2006): 57–58. http://dx.doi.org/10.1042/bio02805057.
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Melonie Thomas, a newly qualified Biomedical Science graduate from Southampton University, was the youngest delegate presenting at BioScience2006. Throughout school and university, students face hefty decisions as they pick their options. Many will probably have some doubt about what to study, why they want to study it or where it will take them. Not everyone has a long-term plan, especially at the age of 17, and it's important to point out that (sometimes) this is okay. Melonie claims not to have enjoyed science at school. She didn't even know about Biochemistry when she selected her AS options of Maths, French, English Literature, Business Studies and General Studies, along with a Spanish GCSE. Not a promising choice of interviewee for The Biochemist you might think, but all will become clear… as it did to Melonie.
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Narasimhan, D., T. S. Sunilkumar, E. V. S. S. K. Babu, and N. Krishna Rao. "Occurrence of Palladian Melonite in Jaduguda Uranium Deposit, Singhbhum Shear Zone, Bihar." Journal Geological Society of India 51, no. 6 (1998): 759–60. http://dx.doi.org/10.17491/jgsi/1998/510605.
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S. D., Misar. "Molluscan Diversity in and Around Sakharwahi Lake Near Chandrapur Maharashtra India." International Journal for Research in Applied Science and Engineering Technology 10, no. 1 (2022): 376–79. http://dx.doi.org/10.22214/ijraset.2022.39850.
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Abstract: The present study was conducted on the molluscan diversity in and around Sakharwahi lake of Chandrapur district, which harbors a variety of flora as well as fauna in the submerged as well as floating state, due to availability of ample of food and suitable condition. During the study total 19 species molluscs were found out of which 16 species of Gastropoda and 3 species of Bivalvia were collected from Sakharwahi lake which belongs to family Vivipiridea, Thiaridae, Melonidea, Lymnaeidae, Planorbidae, Valloniidae, Unionidae, Parresysiinea. Keywords: Mollusca, Sakharwahi, Gastropods, Bivalvia, Ecosystem
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II, Hiroyuki, and Akihiko OKADA. "Poughite, Frohbergite and Melonite from the Kobetsuzawa Mine, Sapporo, Hokkaido." Journal of the Mineralogical Society of Japan 20, no. 3 (1991): 89–92. http://dx.doi.org/10.2465/gkk1952.20.89.
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El Serite, Farg S., Khaled A. Abdelshafeek, and Hatel El-Kamali. "Toxicity Effects of N. oleander and E. terracina on M. tuberculata and B. alexandrina Snails." مجلة علوم البحار والتقنيات البيئية 3, no. 1 (2017): 18–27. http://dx.doi.org/10.59743/jmset.v3i1.98.
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The molluscicidal activity of different extracts of two species belonging to many families (Nerium oleader and Euphorbia terracina) was evaluated against two types of snails (Melonides tuberculata and Biomphalaria alexandrina) in the agricultural area of Taourghaa region, Libya. The results clearly showed that (The Lc50 – Lc90 for two snails and two plants of ethanol extract between (1.26 and 2143.2 ppm) interference to ethanol extract, also the Lc50and Lc90 for two snails and two plants of acetone extract between (100 and 924.6) ppm.
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Plotinskaya, O., та E. Kovalchuk. "Co and Тi minerals in ores of the Mikheevskoe porphyry Cu deposit (South Urals)". МИНЕРАЛОГИЯ (MINERALOGY) 11, № 1 (2025): 17–27. https://doi.org/10.35597/2313-545x-2025-11-1-2.
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Co and Ni minerals are described in ores of the Mikheevskoe porphyry copper deposit (South Urals, Russia). Minerals of the cobaltite–gersdorfte series (CoAsS–NiAsS), violarite (FeNi2S4), millerite (NiS), pentlandite (Ni5.5Fe3.4)8.9S8.0 and melonite (NiTe2) are identifed. They overgrow pyrite, chalcopyrite and bornite and belong to late low-temperature assemblages. Cobalt and Ni are also incorporated in pyrite. The latter, being the most widespread mineral of the deposit, is a major carrier of these metals. The variability of Co and Ni minerals is determined by the presence of serpentinites, which replaced ultramafc rocks.
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Plotinskaya, O., та E. Kovalchuk. "Co and Тi minerals in ores of the Mikheevskoe porphyry Cu deposit (South Urals)". МИНЕРАЛОГИЯ (MINERALOGY) 11, № 1 (2025): 17–27. https://doi.org/10.35597/2313-545x-2024-11-1-2.
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Co and Ni minerals are described in ores of the Mikheevskoe porphyry copper deposit (South Urals, Russia). Minerals of the cobaltite–gersdorfte series (CoAsS–NiAsS), violarite (FeNi2S4), millerite (NiS), pentlandite (Ni5.5Fe3.4)8.9S8.0 and melonite (NiTe2) are identifed. They overgrow pyrite, chalcopyrite and bornite and belong to late low-temperature assemblages. Cobalt and Ni are also incorporated in pyrite. The latter, being the most widespread mineral of the deposit, is a major carrier of these metals. The variability of Co and Ni minerals is determined by the presence of serpentinites, which replaced ultramafc rocks.
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Fröhlich, Fabian, Janne Siikaluoma, Inga Osbahr, and Jens Gutzmer. "Genesis of sulfide vein mineralization at the Sakatti Ni-Cu-PGE deposit, Finland." Canadian Mineralogist 59, no. 6 (2021): 1485–510. http://dx.doi.org/10.3749/canmin.2100020.
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ABSTRACT The Sakatti Ni-Cu-platinum-group element deposit is situated in northern Finland and comprises massive, disseminated, and vein sulfide mineralization. A stockwork is formed by chalcopyrite-rich sulfide veins, which contain exceptionally high platinum-group elements and Au grades. The mineralogy and geochemistry of this stockwork zone ore is documented in this investigation. The results are used to develop the first robust genetic concept and its relationship to massive and disseminated mineralization of the Sakatti deposit. This model is similar to that proposed for many Cu-rich magmatic sulfide ores, most importantly the Cu-rich footwall veins described from the Sudbury Complex in Canada and the Cu-rich ore at Noril'sk-Talnakh in Russia. Detailed petrographic studies using a sample suite from exploration drill core intersecting vein-style mineralization revealed a classic magmatic sulfide assemblage of chalcopyrite ± pyrrhotite, pentlandite, and pyrite. More than 1000 platinum-group mineral grains belonging almost exclusively to the moncheite (PtTe2) – merenskyite (PdTe2) – melonite (NiTe2) solid solution series were identified in the studied samples. Notably, almost two thirds of the platinum-group element-bearing minerals consist of melonite. Some of the platinum-group minerals contain inclusions of Ag-rich gold (AgAu2) and muthmannite (AuAgTe2). Most of the platinum-group minerals occur as inclusions in chalcopyrite, although a few grains are located at base-metal sulfide grain boundaries and in fractures in base-metal sulfides. The whole-rock compositions of the stockwork veins are Cu-rich and are interpreted to represent a fractionated Cu-rich sulfide liquid enriched in Pt, Pd, Au, Ag, As, Bi, Pb, Se, Te, Zn, which separated from a monosulfide solid solution (mss). An intermediate solid solution (iss) solidified from the Cu-rich sulfide liquid, recrystallizing chalcopyrite at <550 °C. Simultaneously, small volumes of intercumulus residual melt contained mainly the precious metals, Bi, and Te due to their incompatibility in iss. Solitary and composite platinum-group minerals as well as Au-minerals crystallized first from the residual melt (<600 °C), followed by a succession of various Bi-, Ag-, and Pb-tellurides (∼540 °C), and finally sphalerite and galena. Melonite crystallized as mostly large, solitary grains exsolved directly from Ni-bearing intermediate solid solution (∼600 °C), shortly after the formation of moncheite and merenskyite from the residual melt. Finally, remobilization of the platinum-group minerals occurred at temperatures of <300 °C, as suggested by the presence of minor amounts of Cl-bearing minerals and ragged grain shapes.
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Guryanov, V. A., L. L. Petukhova, A. V. Abrazhevich, V. M. Chubarov, and A. I. Tikhomirova. "GEOLOGICAL POSITION, MINERALS OF RARE AND NOBLE METALS IN THE ORES OF THE KUN-MANIE COPPER-NICKEL DEPOSIT (SOUTHEASTERN FRINGE OF THE SIBERIAN PLATFORM)." Tikhookeanskaya Geologiya 41, no. 6 (2022): 3–23. http://dx.doi.org/10.30911/0207-4028-2022-41-56-3-23.
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In this paper we present new data on geology of the Kun-Manie copper-nickel-PGE sulfide deposit of the Kun-Manie ore field located on the eastern periphery of the Pristanovoy orogen in the southeast of the Siberian Platform, as well as a detailed description of ores and basic minerals and the distribution of PGE mineralization in ores of the deposit. The ore bodies are spatially associated with sills of the Late Paleoproterozoic Kun-Manie gabbronorite-websterite-lherzolite complex of 1.76–1.69 Ga. It has been established that the outlines of disseminated Cu-Ni ores and ore-bearing sills of mafic-ultramafic rocks match almost exactly. Breccia and massive ores are confined to schists of the upper and lower parts of the ore shoots. Patchy disseminated and vein-disseminated mineralization is concentrated in zones of ductile deformation and along contacts between rock layers of different competence. The main ore minerals are pyrrhotite, pentlandite and chalcopyrite; less common are pyrite, marcasite, cubanite, bornite, chalcocite, sulfoarsenides (gersdorfite, glaucodot), arsenides (nicolite) and tellurides (melonite) of nickel. Magnetite and ilmenite occur in small amount. PGE mineralization is represented by arsenides (sperrylite), sulfoarsenides (irarsite, holingworthite), tellurides (Pd-melonite, merenskite, kotulskite), and tellurobismuthides (moncheite, michenerite). Arsenides, sulfoarsenides and tellurides of PGE, Ni, Ag and Bi, native gold and silver were found in vein-disseminated, patchy disseminated and breccia Cu-Ni ores. The concentration of a considerable part of the main sulfide minerals and the productivity of PGE mineralization are assumed to be due not only to complex processes of magmatic differentiation, but also to sulfurization of magma differentiates in zones of ductile (tectonic) deformation under the influence of recrystallized fluids. The productivity of PGE mineralization characteristically increases with increasing fluid concentrations of S, As, Te, Bi, and Sb.
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Helmy, Hassan M. "Melonite group minerals and other tellurides from three Cu–Ni–PGE prospects, Eastern Desert, Egypt." Ore Geology Reviews 26, no. 3-4 (2005): 305–24. http://dx.doi.org/10.1016/j.oregeorev.2005.04.001.
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Stigarll, Andrea, and Emmett Elam. "Impact of Improved Landscape Quality and Tree Cover on the Price of Single-Family Homes." Journal of Environmental Horticulture 27, no. 1 (2009): 24–30. http://dx.doi.org/10.24266/0738-2898-27.1.24.
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Abstract Impacts of the quality of landscaping and percentage of tree cover on home prices were estimated from a sample of 75 home sales within the Melonie Park neighborhood in Lubbock, TX, from 2003 to 2005. Estimates were derived using a regression of house sale price on house characteristics, landscape quality, and tree cover. Homes that improved landscaping from average quality to good or excellent quality increased selling price by 5.7 and 10.8%, respectively. Approximately 30% of the increase in sale value was accounted for by added tree cover. The results show that each $1.00 invested in upgrading an average landscape to excellent quality returns $1.35 in added property value.
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Kalinin, Arkadii A. "Tellurium and Selenium Mineralogy of Gold Deposits in Northern Fennoscandia." Minerals 11, no. 6 (2021): 574. http://dx.doi.org/10.3390/min11060574.
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Mineralization of Te and Se was found in gold deposits and uranium occurrences, located in the Paleoproterozoic greenstone belts in Northern Fennoscandia. These deposits are of different genesis, but all of them formed at the late stages of the Svecofennian orogeny, and they have common geochemical association of metals Au, Cu, Co, U, Bi, Te, and Se. The prevalent Te minerals are Ni and Fe tellurides melonite and frohbergite, and Pb telluride altaite. Bismuth tellurides were detected in many deposits in the region, but usually not more than in two–three grains. The main selenide in the studied deposits is clausthalite. The most diversified selenium mineralization (clausthalite, klockmannite, kawazulite, skippenite, poubaite) was discovered in the deposits, located in the Russian part of the Salla-Kuolajarvi belt. Consecutive change of sulfides by tellurides, then by selenotellurides and later by selenides, indicates increase of selenium fugacity, fSe2, in relation to fTe2 and to fS2in the mineralizing fluids. Gold-, selenium-, and tellutium-rich fluids are potentially linked with the post-Svecofennian thermal event and intrusion of post-orogenic granites (1.79–1.75 Ga) in the Salla-Kuolajarvi and Perapohja belts. Study of fluid inclusions in quartz from the deposits in the Salla-Kuolajarvi belt showed that the fluids were high-temperature (240–300 °C) with high salinity (up to 26% NaCl-eq.). Composition of all studied selenotellurides, kawazulite-skippenite, and poubaite varies significantly in Se/Te ratio and in Pb content. Skippenite and kawazulite show the full range of Se-Te isomorphism. Ni-Co and Co-Fe substitution plays an important role in melonite and mattagamite: high cobalt was detected in nickel telluride in the Juomasuo and Konttiaho, and mattagamites from Ozernoe and Juomasuo contain significant Fe. In the Ozernoe uranium occurrence, the main mineral-concentrator of selenium is molybdenite, which contains up to 16 wt.% of Se in the marginal parts of the grains. The molybdenite is rich in Re (up to 1.2 wt.%), and the impurity of Re is irregularly distributed in molybdenite flakes and spherulites.
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Safina, N. P., L. Ya Kabanova, and I. A. Blinov. "Mineralogy of host rocks of the Osinovskoe gold-quartz deposit (Central Urals)." МИНЕРАЛОГИЯ (MINERALOGY) 9, no. 4 (2023): 17–36. http://dx.doi.org/10.35597/2313-545x-2023-9-4-2.
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The paper describes the mineralogy of mica shales of the Osinovskoe gold deposit in the Central Urals. Our studies unraveled the role of dynamometamorphism in the transformation of primary rocks and allowed the characterization of their metasomatic alteration. We showed the relationship between plastic and brittle deformations and the formation of gold-bearing mineral assemblage with major pyrite, pyrrhotite and ilmenite and subordinate and rare sphalerite, chalcopyrite, marcasite, rutile, magnetite, molybdenum, galena, altaite, hessite, melonite, petzite, calaverite, volynskite, and sylvanite. The Ag content of native gold varies from 4 to 29 wt. %. Tellurides are associated with pyrite and pyrrhotite and also form monomineral grains and intergrowths in chlorite and mica with inclusions of REE minerals (xenotime-(Y), monazite-(Ce), hydroxylbastnesite-(Ce)), allanite-(Ce)), REE-bearing minerals (epidote, apatite, zircon), Th silicate (torite), and uraninite.
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Garuti, G., and R. Rinaldi. "Mineralogy of melonite-group and other tellurides from the Ivrea-Verbano basic complex, western Italian Alps." Economic Geology 81, no. 5 (1986): 1213–17. http://dx.doi.org/10.2113/gsecongeo.81.5.1213.
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Kasatkin, A. V., M. V. Tsyganko, and F. Nestola. "Tellurium mineralization of the Priozernoe gold-quartz deposit (Northern Urals, Russia)." МИНЕРАЛОГИЯ (MINERALOGY) 9 (March 29, 2023): 5–22. http://dx.doi.org/10.35597/2313-545x-2023-9-1-1.
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Primary and supergene Te minerals are identifed in quartz veins of the Priozernoe deposit (Sverdlovsk oblast, Northern Urals, Russia) and studied by optical methods, electron microprobe analysis, X-ray diffraction and Raman spectroscopy. Tellurides include altaite, hessite, melonite, petzite, and sylvanite. Their individual grains and intergrowths occur as small inclusions in quartz. Supergene minerals include telluroperite, northstarite, adanite, burckhardtite, kuranakhite, and schieffelinite. They replace galena, hessite and cerussite or form monomineral grains and veinlets in quartz. Northstarite, adanite, and schieffelinite are found for the frst time in Russian Federation, while the fndings of telluroperite and burckhardtite are second. Kuranakhite is found for the frst time in the Northern Urals. The fndings of supergene Te minerals in Russia are reviewed. Keywords: Priozernoe deposit, Northern Urals, tellurium mineralization, tellurides, tellurates, north-starite, adanite, schieffelinite, burckhardtite, frst fnds of minerals in Russia, supergene minerals.
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Barkov, Andrei Y., Luca Bindi, Nobumichi Tamura, et al. "Ognitite, NiBiTe, a new mineral species, and Co-rich maucherite from the Ognit ultramafic complex, Eastern Sayans, Russia." Mineralogical Magazine 83, no. 5 (2019): 695–703. http://dx.doi.org/10.1180/mgm.2019.31.
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AbstractWe describe the new species ognitite, NiBiTe, and a Co-rich variety of maucherite, hitherto unreported; both were discovered in the Ognit ultramafic complex of Neoproterozoic age in Eastern Sayans, Russia. The mean composition of ognitite (n = 7) is: Ni 17.05, Fe 0.07, Cu 0.14, Pd 0.14, Te 32.53, Bi 49.64, total 99.57 wt.%, corresponding to: (Ni1.11Cu0.008Fe0.005Pd0.005)Σ1.13Bi0.90Te0.97 (Σ atoms = 3 apfu). Ognitite is trigonal, space group P3m1 [R1 = 0.0276 for 81 reflections with Fo > 4σ(Fo)]. The unit-cell parameters derived from the single-crystal X-ray diffraction data are: a = 3.928(1) Å, c = 5.385(1) Å and V = 71.95(4) Å3, with Z = 1. The c:a ratio is 1.37. The powder X-ray diffraction data obtained on the same fragment used for the single-crystal study are: a = 3.9332(4) Å, c = 5.3920(6) Å and V = 72.24(1) Å3. Ognitite exhibits the brucite-type structure with edge-sharing NiTe3Bi3 octahedra forming sheets parallel to (0001). It is related to melonite, but is distinct compositionally by the extreme Bi-enrichment (melonite and its synthetic analogue contain <0.4 Bi apfu), and structurally as Bi and Te are ordered at two distinct sites, leading to the loss of the centre of symmetry in ognitite.At more than 9 wt.% Co, or ~2 apfu Co, the core of Co-rich maucherite [(Ni,Co)11As8] in a zoned crystal, which is surrounded by Co-depleted orcelite, far surpasses the norm (≤1 and up to 3.9 wt.% Co). The unit-cell parameters of the Co-rich maucherite are: a = 6.85(2) and c = 21.83(5) Å, which are based on results of synchrotron micro-Laue diffraction.The host rock consists of serpentine, clinochlore (Mg# 95–97) and skeletal chromite. We favour the metastable crystallisation of fluid-saturated globules of a sulfide–arsenide melt to explain the anomalous compositions of ore minerals at Ognit. These anomalies seem consistent with rapid cooling in a fluid-enriched system, possibly related to late-stage degassing of the magma, as reflected in a prominent metasomatic aureole at the contact with the enclosing gneissic rocks.
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ÖZKAYA, Senem, and Emine Mine SOYLU. "Determination of antagonistic effects antagonist bacterial isolates obtained from composts against melon wilt disease agent Fusarium oxysporum f.sp. melonis in vitro conditions." Mustafa Kemal Üniversitesi Tarım Bilimleri Dergisi 27, no. 3 (2022): 565–77. http://dx.doi.org/10.37908/mkutbd.1139502.
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Amaç: Bu çalışmada zeytin, pamuk ve hayvansal atıklardan yapılmış 5 farklı komposttan antagonistik etkinliğe sahip bakterilerin izolasyonu, tanılanması ve kavun solgunluk hastalığı etmeni Fusarium oxysporum f. sp. melonis (Fom)’in misel gelişimini engellemeleri üzerine olan etkinlikleri in vitro koşullarda araştırılmıştır.Yöntem ve Bulgular: Kompostların fermentasyon süresine bağlı olarak bakteriyel popülasyon sayısında artış görülmüştür. En yüksek bakteri popülasyonu fermentasyonun 3 ve 4. aylarında belirlenmiştir. Farklı kompost materyallerinden izole edilen antagonist adayı bakteri izolatları Yağ Asit-Metil Ester (FAME) profillerine göre Mikrobiyal Tanılama Sistemi (MIS) ile teşhis edilmiştir. Aday bakterilerin Fom’in misel gelişimini engelleme potansiyelleri ikili kültür testleri ile belirlenmiştir. Elde edilen aday bakteriyel izolatlar arasında 31 bakteri izolatı ikili kültür denemelerinde, Fom’in misel gelişimini engellenmesi üzerine değişik oranlarda antagonistik etkinlik göstermiştir. Antagonistik potansiyele sahip bakteri izolatlarının çoğunluğunu farklı Bacillus spp.’a ait izolatlar (% 73.3) oluşturmuştur. Farklı kompost materyallerinden izole edilen bakteriler arasında en yüksek antagonistik etki %48.33 engelleme oranı ile Entereobacter gergoviae K4B:4:7:1 izolatı tarafından gösterilmiş olup, bu izolatı sırasıyla Bacillus cereus K1B:4:8:1 (%47.5), Salmonella typhimurium K5B:1:4:3 (% 46.67), Bacillus amyloliquefaciens K5B:0:5:1 (%43.33) ve Bacillus subtilis K3B:4:8:1 (%40.83) izolatları izlemiştir.Genel Yorum: Organik atıklardan hazırlanmış kompostlar toprak kökenli hastalıklara karşı etkin antagonistik etkiye sahip bakterilere konukçuluk etmektedir. Kompostların in vivo koşullarda Fom’e karşı kullanılma potansiyellerinin araştırılmasının yanı sıra buralardan biyolojik preparat olarak kullanıma en uygun olan bakteri izolatların seçimi ve hastalığı engellemede kullandıkları mekanizmaların belirlenmesi üzerine çalışmalar gelecekte sürdürülmelidir.Çalışmanın Önemi ve Etkisi: Elde edilen sonuçlar, Fom’in biyolojik mücadelesinde antagonistik potansiyele sahip mikroorganizmaların yoğun olarak geliştiği kompostların seralar gibi sınırlı alana sahip yetiştirme alanlarında kullanılmasının etkin bir rol oynayabileceğini göstermiştir.
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ÜNLÜ, Mine, Rana KURUM, İlknur POLAT, Abdullah ÜNLÜ, and Görkem SÜLÜ. "Kavun ıslah programında geliştirilen aday hibritlerin Fusarium oxysporum f. sp. melonis’e moleküler olarak dayanıklılık durumlarının tespiti ve verim değerlerinin belirlenmesi." Derim 31, no. 2 (2014): 1. http://dx.doi.org/10.16882/derim.2014.04107.
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Vanin, V. A. "FEATURES OF THE MATERIAL COMPOSITION OF THE VERKHNEYANSKY GOLD-ORE FIELD BREEDS (NORTH BAYKAL)." EurasianUnionScientists 1, no. 11(56) (2018): 47–52. http://dx.doi.org/10.31618/esu.2413-9335.2018.1.56.47-52.
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The mineralogical and geochemical features and the material composition of the ore metaso-matites of the Verkhneyanskoye gold ore field (VGOF) have been studied. VGOF is located in the northern part of the Baikal-Muya belt. Ore bodies are represented by linear stockwork of gold-bearing metasomatites that trace the ore-controlling fault zone. Host rocks are ayulindinskiy metavolcanogenic formation, granitoids and gabbros of the yano-mamakan complex. The rocks in the fault zone have been changed to the ore stage. Аs a result, gold bearing (albite) sericite-quartz-chlorite-carbonate metasomatites and gold-bearing quartz-carbonate vein metaso-matites were formed. At the ore stage, the transformation of enclosing rocks into the fault zone with the formation of gold-bearing (albite) sericite-quartz-chlorite-carbonate metasomatites and gold-bearing quartz-carbonate vein. Gold-bearing pyrite-II and pyrite-III-chalcopyrite-II-galena associations were identified on the territory of the VZRP. Free gold and gold in the form of tellurides (petzite, calaverite) in association with altaite and melonite was found in ore bodies
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Kouamé, Tapé, Guillaume Bernadat, Victor Turpin, et al. "Structure Reassignment of Melonine and Quantum-Chemical Calculations-Based Assessment of Biosynthetic Scenarios Leading to Its Revised and Original Structures." Organic Letters 23, no. 15 (2021): 5964–68. http://dx.doi.org/10.1021/acs.orglett.1c02055.
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Sari, Ni Kadek Yunita, Anak Agung Ayu Putri Permatasari, Ni Putu Widya Astuti, and Dylla Hanggaeni Dyah Puspaningrum. "PKM KELOMPOK TANI MILENIAL DI DESA CEPAKA, KEDIRI TABANAN." JURNAL WIDYA LAKSANA 10, no. 2 (2021): 136. http://dx.doi.org/10.23887/jwl.v10i2.30883.
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Salah satu perkebunan pandan wangi di Bali adalah kelompok tani milenial mengusung nama UD Melonila, yang terletak di Jalan Raya Munggu Kapal, Banjar Batanduren Desa Cepaka, Kediri, Tabanan, Bali. Sejauh ini pengembangan produk dari tanaman pandan wangi belum dilakukan. Inovasi pemanfaatan daun pandan wangi untuk membuat produk seperti simplisia masih belum dikembangkan. Sehingga Tim PKM berencana untuk melakukan pendampingan terhadap kelompok tani milenial di Desa Cepaka, Kediri, Tabanan untuk membuat produk simplisia. Permasalahan mitra:1)Mitra belum memiliki konsep dasar simplisia 2)Mitra belum memiliki keterampilan dalam membuat produk simplisia, 3)Mitra belum memiliki merk dagang dan kemasan produk hasil pengembangan produk. Solusi yang ditawarkan yaitu 1)Pelatihan melalui penyuluhan tentang konsep dasar simplisia meliputi definisi simplisia, kegunaan dan metode pengolahan daun pandan wangi menjadi simplisia, 2)Pelatihan dan pendampingan praktek membuat produk simplisia, 3)Pendampingan dan pelatihan membuat merk dagang dan desain kemasan. Hasil yang diperoleh dari PKM yaitu 1)Semua anggota mitra yang mengikuti sosialisasi mendapatkan rerata nilai pemahaman 84 pada post-test, 2)Mitra memiliki keterampilan dalam membuat produk simplisia, 3)Produk simplisia yang dihasilkan memiliki merek dagang dan kemasan penjualan. Kata Kunci : Desa Cepaka, Kelompok Tani Milenial, Simplisia, Pandan Wangi
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Permatasari, Anak Agung Ayu Putri, Ni Kadek Yunita Sari, and I. Made Endra Puniawan. "PKM PEMANFAATAN LIMBAH TANAMAN PANDAN WANGI DI DESA CEPAKA, KEDIRI, TABANAN." JURNAL WIDYA LAKSANA 11, no. 1 (2022): 55. http://dx.doi.org/10.23887/jwl.v11i1.32530.
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Tanaman pandan wangi tumbuh subur di negara beriklim tropis, yang biasanya dimanfaatkan sebagai campuran bahan masakan untuk membuatnya wangi dan enak. Daun pandan wangi mengandung zat alkaloida, polifenol, flavonoida, tannin, saponin dan juga zat warna alami. Senyawa tersebut dapat berperan sebagai anti bakteri, mengontrol kadar gula darah, mencegah kanker, mengatasi masalah gigi dan gusi, mengatasi kram, mengurangi rambut rontok dan masalah sakit kepala.. Salah satu perkebunan pandan wangi yang terdapat di Bali yaitu UD. Melonila, yang terletak di Jalan Raya Munggu Desa Cepaka, Tabanan Bali. Hasil perkebunan pandan wangi biasanya dipasarkan ke pasar tradisional. Setelah dipanen tanaman ini harus segera didistribusikan agar tetap segar. Sedangkan tanaman yang merupakan sisa hasil panen memiliki kualitas yang hampir sama, tumbuh dengan cepat akan tetapi tidak mudah untuk dipasarkan. Oleh karena itu banyaknya hasil panen dari tanaman pandan wangi ini yang selalu tumbuh dengan cepat dan mudah menjadi permasalahan yang dialami oleh mitra, sehingga mitra ingin berinovasi mengembangkan produk dari limbah tanaman kemangi menjadi desinfektan alami. Oleh karena itu dilakukan pengembangan terhadap produk dengan menentukan merk dagang dan desain kemasan serta pemasaran produk yang dilakukan melalui sosial media. Berdasarkan hasil PKM didapatkan bahwa kelompok tani mengalami rata-rata peningkatan pengetahuan mengenai pemanfaatan limbah pandan wangi sebesar 83%. Kata Kunci : Desa Cepaka, desinfektan alami, inovasi, pemasaran
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Bergh, Eugene W., and John S. Compton. "Taxonomy of Middle Miocene foraminifera from the northern Namibian continental shelf." Zootaxa 5091, no. 1 (2022): 1–55. https://doi.org/10.11646/zootaxa.5091.1.1.
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Firstova, Anna, Tamara Stepanova, Anna Sukhanova, Georgy Cherkashov, and Irina Poroshina. "Au and Te Minerals in Seafloor Massive Sulphides from Semyenov-2 Hydrothermal Field, Mid-Atlantic Ridge." Minerals 9, no. 5 (2019): 294. http://dx.doi.org/10.3390/min9050294.
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The Semyenov-2 hydrothermal field located at 13°31′N of the Mid-Atlantic Ridge (MAR) is associated with an oceanic core complex (OCC) and hosted by peridotites and basalts with minor amounts of gabbro and plagiogranites. Seafloor massive sulphides (SMS) are represented by chimneys with zonality, massive sulphides without zonality and sulphide breccia cemented by opal and aragonite. The mean value of Au (20.6 ppm) and Te (40 ppm) is much higher than average for the MAR SMS deposits (3.2 ppm and 8.0 ppm, respectively). Generally, these high concentrations reflect the presence of a wide diversity of Au and Te minerals associated with major mineral paragenesis: primary native gold, melonite (NiTe2) and tellurobismuthite (Bi2Te3) are related to high-temperature chalcopyrite (~350 °C); electrum (AuAg)1, hessite (Ag2Te) and altaite (PbTe) are related to medium- and low-temperature Zn-sulphide and opal assemblages (260–230 °C). Calaverite (AuTe2) and Te-rich “fahlore” Cu12(Sb,As,Te)4S13 are texturally related to the chalcopyrite-bornite-covellite. Enrichment of Au in sulphide breccia with opal and aragonite cement is driven by the re-deposition and the process of hydrothermal reworking of sulphide. The low-temperature fluid mobilizes gold from primary sulphide, along with Au and Te minerals. As a result, the secondary gold re-precipitate in cement of sulphide breccia. An additional contribution of Au enrichment is the presence of aragonite in the Cu-Zn breccia where the maximal Au content (188 ppm) is reached.
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Spiridonov, E. M., S. N. Belyakov, N. N. Korotayeva, et al. "Menshikovite Pd<sub>3</sub>Ni<sub>2</sub>As<sub>3</sub> and associated minerals of sulphide ores within the Eastern flank of the Oktyabrsky deposit (Norilsk ore field)." Moscow University Bulletin. Series 4. Geology, no. 4 (August 28, 2020): 22–29. http://dx.doi.org/10.33623/0579-9406-2020-4-22-29.
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Significant amount of menshikovite (rare palladium and nickel arsenide) Pd3Ni2As3 was found on the Eastern flank of the Oktyabrsky deposit (Norilsk ore field), near the contact of solid and impregnation sulfide Co-Ni-Cu ores among magnetite-plagioclase-fassaite skarns. Sulfide material of both ores consists of chalcopyrite, pentlandite, pyrrhotite and cubanite aggregates, which are the products of subsolidus transformations of high-temperature solid solutions Iss3, Iss4 and subordinate Mss; with interpositions of later Se-galenite. Menshikovite in association with mertieite-II, silver-gold (fineness 756–706), golden-electrum (fineness 694–672), kotulskite, moncheite, rare altaite, hessite, naldrettite and melonite forms small (up to 30 microns) metasomatic growths on the contact of silicate matrix and magmatogenic sulfide aggregates. The average composition of menshikovite is close to theoretical data: (Pd2,98Ru0,03)3,01(Ni1,89Fe0,-08Co0,01)1,98 (As2,94Se0,04Bi0,02Sn0,01)3,01. Sperrylite metacrystals cut the borders of menshikovite accretions as well as other minerals of precious metals and contain “corroded” inclusions. This association of minerals of noble metals has arisen under the increased activity of As, Te, Sb, Bi and low activity of Sn in fluids. Menshikovite is typical for Pd-rich ores of the Oktyabrsky Deposit, while mayakite PdNiAs (another palladium and nickel arsenide) is relatively widely developed in ores of the Talnakh Deposit (Mayak mine and partly Komsomolsky mine) and the Norilsk-I. Perhaps, such a distribution of palladium-nickel arsenides is an element of mineral zonality of the Norilsk ore field.
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Eliopoulos, Demetrios G., Maria Economou-Eliopoulos, George Economou, and Vassilis Skounakis. "Mineralogical and Geochemical Constraints on the Origin of Mafic–Ultramafic-Hosted Sulphides: The Pindos Ophiolite Complex." Minerals 10, no. 5 (2020): 454. http://dx.doi.org/10.3390/min10050454.
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Sulphide ores hosted in deeper parts of ophiolite complexes may be related to either primary magmatic processes or links to hydrothermal alteration and metal remobilization into hydrothermal systems. The Pindos ophiolite complex was selected for the present study because it hosts both Cyprus-type sulphides (Kondro Hill) and Fe–Cu–Co–Zn sulphides associated with magnetite (Perivoli-Tsoumes) within gabbro, close to its tectonic contact with serpentinized harzburgite, and thus offers the opportunity to delineate constraints controlling their origin. Massive Cyprus-type sulphides characterized by relatively high Zn, Se, Au, Mo, Hg, and Sb content are composed of pyrite, chalcopyrite, bornite, and in lesser amounts covellite, siegenite, sphalerite, selenide-clausthalite, telluride-melonite, and occasionally tennantite–tetrahedrite. Massive Fe–Cu–Co–Zn-type sulphides associated with magnetite occur in a matrix of calcite and an unknown (Fe,Mg) silicate, resembling Mg–hisingerite within a deformed/metamorphosed ophiolite zone. The texture and mineralogical characteristics of this sulphide-magnetite ore suggest formation during a multistage evolution of the ophiolite complex. Sulphides (pyrrhotite, chalcopyrite, bornite, and sphalerite) associated with magnetite, at deeper parts of the Pindos (Tsoumes), exhibit relatively high Cu/(Cu + Ni) and Pt/(Pt + Pd), and low Ni/Co ratios, suggesting either no magmatic origin or a complete transformation of a preexisting magmatic assemblages. Differences recorded in the geochemical characteristics, such as higher Zn, Se, Mo, Au, Ag, Hg, and Sb and lower Ni contents in the Pindos compared to the Othrys sulphides, may reflect inheritance of a primary magmatic signature.
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Melekestseva, I. Yu, V. V. Zaykov, G. A. Tret’yakov, K. A. Filippova та V. A. Kotlyarov. "Geological structure and mineralogy of the Mechnikovskoe gold deposit, thе Southern Urals". LITOSFERA, № 1 (17 березня 2019): 111–38. http://dx.doi.org/10.24930/1681-9004-2019-19-1-111-138.
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Subject. The article presents the results of study of Mechnikovskoe gold deposit associated with listvenites and beresites of the Miass region of the Southern Urals.Materials and methods. Materials were sampled during the field work of 2010– 2012. The chemical composition of rocks is analyzed by methods of classical chemistry (rock-forming oxides) and ICP MS (trace elements). The mineral composition is determined on an electron microscope with EDS.Results. The deposit is composed of tectonic sheets of serpentinites, carbonatized serpentinites and listvenites (sheet I), metadiabases and plagioclase metabasalts of the Irendyk Formation and beresites and volcanosedimentary rocks and metabasalts of the Karamalytash Formation (sheet II). In the central part of the deposit, the volcanic rocks are intruded by a dike of finegrained island-arc granites. Chromites of serpentinites are characterized (on average) by high Cr# (89) and low Mg# (29) values and low contents of Al2O3 (6.94 wt %) and MgO (5.5 wt %). Gold-bearing rocks include listvenites, beresites and carbonaceous shales. The major ore mineral is pyrite; accessory minerals are Au and Ag minerals, chalcopyrite, fahlores, galena, sphalerite, pyrrhotite, cubanite, vaesite, melonite, secondary copper sulfides, barite, rutile, monazite and xenotime. Gold of the deposit contains low Ag contents (3.52 wt %) and minor amount of Cu and Hg (<1 wt % in most analyses).Conclusions. The listvenites and beresites of the deposit were formed after ultramafic and mafic rocks, respectively. The discovery of gold in various rocks indicates that gold mineralization was deposited after the formation of the geological structure of the deposit. The source of gold was most likely related to a magmatic fluid.
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Weng, Guoming, Jiajun Liu, Emmanuel John M. Carranza, et al. "Mineralogy of Gold, Tellurides and Sulfides from Lianzigou Gold Deposits in the Xiaoqinling Region, Central China: Implications for Ore-Forming Conditions and Processes." Minerals 14, no. 7 (2024): 675. http://dx.doi.org/10.3390/min14070675.
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The Lianzigou deposit, which has an Au–Te paragenetic association, is hosted in plagioclase gneiss of the Qincanggou Formation in the Taihua Group in the Xiaoqinling region, central China. This quartz vein-type Au deposit comprises native Au and a variety of tellurides. The latter include calaverite (AuTe2), krennerite (Au3AgTe8), petzite (Au3AgTe2), hessite (Ag2Te), melonite (NiTe2), and altaite (PbTe). Four stages have been recognized in this deposit: stage I consists of K-feldspar and quartz; stage II is of milky quartz veins accompanied by coarse-grained disseminated and lumps of pyrite with weak Au mineralization; stage III is composed mainly of Au, tellurides, and sulfides; and stage IV is characterized by abundant carbonate and quartz. Based on mineral assemblage and thermodynamic data, we estimated the physicochemical conditions of the main metallogenic stages. Based on thermodynamic modelling, the physicochemical conditions of Au–Ag–Te mineral associations were estimated. The Au–Ag–Te minerals from stage III formed mainly under conditions of logƒO2 = −43.15 to −33.31, logƒH2S = ~−9.29, pH < 7, logfTe2 = −10.6 to −9.8 and logαAu+/αAg+ = −7.2 to −6.5. In contrast, the physicochemical conditions of stage II were higher, specifically pH (8.3–8.5) and logƒO2 (−34.90−31.96). In the ore-forming fluids of the Lianzigou deposit, the dominant Au species was Au(HS)2− while the dominant Te species were HTe−(aq) and Te22−(aq). Moreover, the Au–Ag–Te metal associations in the Lianzigou Au deposit were derived from mantle materials related to lithospheric thinning of the eastern North China craton in the Early Cretaceous under an extensional tectonic system.
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Xu, Jing, Cristiana Liana Ciobanu, Nigel John Cook, Shen Gao, Taiping Zhao, and Jichen Jiang. "Constraints on Ore Genesis from Trace Ore Mineralogy: A New Occurrence of Kupčíkite and Paděraite from the Zhibula Cu Skarn Deposit, Southern Tibet." Minerals 14, no. 5 (2024): 474. http://dx.doi.org/10.3390/min14050474.
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Mineral assemblages containing Cu-Bi sulfosalts, Bi chalcogenides, and Ag-(Au) tellurides have been identified in the mid-Miocene Zhibula Cu skarn deposit, Gangdese Belt, southern Tibet. Different mineral assemblages from three locations in the deposit, including proximal massive garnet skarn, proximal retrogressed pyroxene-dominant skarn in contact with marble, and distal banded garnet–pyroxene skarn hosted in marble, are studied to constrain the evolution of the mineralization. Hypogene bornite contains elevated Bi (mean 6.73 wt.%) and co-exists in proximal andradite skarn with a second bornite with far lower Bi content, carrollite, Au-Ag tellurides (hessite, petzite), and wittichenite. This assemblage indicates formation at relatively high temperatures (>400 °C) and high fS2 and fTe2 during prograde-stage mineralization. Assemblages of Bi sulfosalts (wittichenite, aikinite, kupčíkite, and paděraite) and bismuth chalcogenides (e.g., tetradymite) in proximal pyroxene skarn are also indicative of formation at relatively high temperatures, but at relatively lower fTe2 and fS2 conditions. Within the reduced distal skarn (chalcopyrite–pyrrhotite-bearing) in marble, cobalt, and nickel occur as discrete minerals: cobaltite, melonite and cobaltic pentlandite. The trace ore mineral signature of the Zhibula skarn and the distributions of precious and critical trace elements such as Ag, Au, Co, Te, Se, and Bi support an evolving magmatic–hydrothermal system in which different parts of the deposit each define ore formation at distinct local physicochemical conditions. This is the first report of kupčíkite and paděraite from a Chinese location. Their compositions are comparable to other occurrences, but conspicuously, they do not form nanoscale intergrowths with one another.
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Gervilla, Fernando, Alejandro Sáncnez-Anguita, Rogelio D. Acevedo, Purificación Fenoll Hach-Ali, and Andres Paniagua. "Platinum-group element sulpharsenides and Pd bismuthotellurides in the metamorphosed Ni-Cu deposit at Las Aguilas (Province of San Luis, Argentina)." Mineralogical Magazine 61, no. 409 (1997): 861–77. http://dx.doi.org/10.1180/minmag.1997.061.409.09.
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AbstractThe Las Aguilas Ni-Cu-PGE deposit is associated with a sequence of basic-ultrabasic rocks made up of dunite, harzurgite, norite and amphibolite. These igneous (partially metamorphosed) rocks, and their host granulites, gneisses and migmatites of probable Precambrian age, are highly folded. The sulphide ore, consisting of pyrrhotite, pentlandite and chalcopyrite, occurs in the cores of both antiform and synform structures, within dunite, harzburgite and mainly along shear zones in bronzitite, replacing small mylonitic subgrains. The platinum-group mineral assemblage is dominated by Pd bismuthotellurides (Pt-free merenskyite, palladian bismuthian melonite and michenerite), with minor sperrylite, and PGE-sulpharsenides. The latter often occur as single, zoned crystals frequently showing cores of irarsite; outside these are concentric zones of cobaltian hollingworthite, rhodian nickelian cobaltite and Fe-rich nickelian cobaltite.Mineralogical, textural and chemical evidence indicate that the sperrylite and platinum-group element sulpharsenides were formed during a primary magmatic event associated with the fractionation of a basaltic melt, which was contaminated by the assimilation of metamorphic crustal rocks. PGE sulpharsenides crystallized from As-bearing, residual magmatic liquids that collected PGE and segregated after the crystallization of the monosulfide solid solution. During high-grade metamorphism, sulpharsenides were remobilized as solid crystals in the liquated sulfides suffering partial dissolution and fracturing. On the other hand, there is no evidence of a primary concentration of Pd-bismuthotelluride minerals, and their present spatial distribution is only the consequence of their formation under high- to medium-grade metamorphism, down to temperatures of below 500°C. Pd bismuthotellurides crystallize even in fractures of sulpharsenides, attached to the boundaries of highly dissolved sulpharsenide crystals, and intergrown with molybdenite.
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Setoyama, Eiichi, and Michael A. Kaminski. "Neogene benthic foraminifera from the southern Bering Sea (IODP Expedition 323)." Palaeontologia Electronica 76, no. 4 (2015): 1–30. https://doi.org/10.26879/462.
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Setoyama, Eiichi, Kaminski, Michael A. (2015): Neogene benthic foraminifera from the southern Bering Sea (IODP Expedition 323). Palaeontologia Electronica (International ed. in English) 76 (4): 1-30, DOI: 10.26879/462, URL: https://doi.org/10.26879/462
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Mascarella, Marco Antonio, Tolani Olonisakin, Purva Rumde, et al. "Abstract 4338: Response to neoadjuvant targeted therapy in operable head and neck cancer confers survival benefit." Cancer Research 83, no. 7_Supplement (2023): 4338. http://dx.doi.org/10.1158/1538-7445.am2023-4338.
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Abstract Purpose: Neoadjuvant targeted therapy provides a brief, preoperative ‘window of opportunity’ that can be exploited to individualize cancer care based on treatment response. We investigated whether response to neoadjuvant therapy during the preoperative window confers survival benefit in patients with operable head and neck squamous cell carcinoma (HNSCC). Patients and Methods: A pooled analysis of treatment naïve patients with operable HNSCC enrolled in one of three clinical trials from 2009-2020 (NCT00779389, NCT01218048, NCT02473731). Neoadjuvant regimens consisted of EGFR inhibitors (n=83) or anti-ErbB3 antibody therapy (n=9) within 28 days of surgery. Clinical to pathologic stage migration was compared to disease-free survival (DFS) and overall survival (OS) while adjusting for confounding factors using multivariable Cox regression. Circulating tumor markers validated in other solid tumor models were analyzed. Results: 92 of 118 patients were analyzed; all patients underwent surgery following neoadjuvant therapy. Clinical to pathologic downstaging was more frequent in patients undergoing neoadjuvant targeted therapy compared to a historic cohort without neoadjuvant therapy (P=0.048). Patients with pathologic downstage migration had the highest OS (89.5%, 95% CI 75.7-100) compared to those with no stage change (58%, 95% CI 46.2-69.8) or upstage (40%, 95% CI 9.6-70.4, P=0.003). On multivariable analysis, downstage migration remained a positive prognostic factor for OS (hazard ratio 0.22, 95% CI 0.05-0.90) while adjusting for measured confounders. Downstage migration correlated with decreased circulating tumor markers, SOX17 and TAC1 (P=0.0078). Conclusion: Brief neoadjuvant therapy achieved pathologic downstaging in a subset of patients and was associated with significantly better DFS and OS as well as decreased circulating methylated SOX17 and TAC1. Citation Format: Marco Antonio Mascarella, Tolani Olonisakin, Purva Rumde, Varun Vendra, Melonie Nance, Seungwon Kim, Mark Kubik, Shaum Sridharan, Robert Ferris, Moon Fenton, Daniel Clayburgh, James Ohr, Malabika Sen, Sonali Joyce, James Herman, Jennifer Grandis, Dan Zandberg, Umamaheswar Duvvuri. Response to neoadjuvant targeted therapy in operable head and neck cancer confers survival benefit. [abstract]. In: Proceedings of the American Association for Cancer Research Annual Meeting 2023; Part 1 (Regular and Invited Abstracts); 2023 Apr 14-19; Orlando, FL. Philadelphia (PA): AACR; Cancer Res 2023;83(7_Suppl):Abstract nr 4338.
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Jones, Gemma N., Sonia Iyer, Marta Milo, et al. "Abstract CT198: Immunomodulatory effects of the ATR inhibitor ceralasertib in a window of opportunity biomarker trial in patients with head and neck squamous cell carcinoma." Cancer Research 83, no. 8_Supplement (2023): CT198. http://dx.doi.org/10.1158/1538-7445.am2023-ct198.
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Abstract Head and neck squamous cell carcinoma (HNSCC) is frequently locally advanced, but has a high risk of recurrence after initial treatment. Immune checkpoint blockade with PD-1/PD-L1 inhibitors has revolutionized treatment in the recurrent setting, but resistance to these therapies frequently occurs. Combination of checkpoint inhibitors with the ATR inhibitor ceralasertib could provide an exciting opportunity, with encouraging clinical activity reported in melanoma and non-small cell lung cancer (Kwon et al. 2022; Kim et al. 2022; Besse et al. OA15.05 IASLC 2022 WCLC). This phase 1b trial provided a unique opportunity to understand the immunomodulatory impact of DNA Damage Response (DDR) inhibitors in a clinical setting. NCT03022409 is an open-label, randomized window of opportunity trial where patients with HNSCC were treated with either the PARP inhibitor olaparib (300mg BID) or ceralasertib (160mg BID) for 9-21 days, prior to definitive surgery (or on-treatment biopsy). 21 patients were randomized; n=12 to ceralasertib and n=9 to olaparib, and ceralasertib data will be presented here. Translational endpoints on frozen and fixed tumor biopsies included spatial pharmacokinetics, pharmacodynamic biomarkers, multiplexed fluorescence of tumor infiltrating immune cells and gene expression panels. Blood assessments included cytokine detection, immune cell phenotyping and gene expression. Primary endpoint analysis utilized a bespoke prognostic immune-focused gene signature and secondary endpoint an IHC immunoscore, both aimed to measure if tumors would shift from a ‘cold’ to ‘hot/active’ immune state. We observed an ‘on-drug’ selective suppression of proliferating Ki67+ T-cells (but not total T-cells) in the tumor microenvironment and periphery, followed by a repopulation and median rebound of 63.8% and 187.5% above baseline levels for peripheral helper (CD4+Ki67+; n=8) and cytotoxic (CD8+Ki67+; n=7) T-cells respectively, when ceralasertib dose stopped. IL-12 plasma cytokine levels dropped on ceralasertib treatment and returned to baseline levels ‘off-drug’ in 8/10 patients. Type-I interferon (IFN1) gene expression associated signatures were also upregulated in PBMCs, suggestive of an immune priming effect. 0/2 and 2/4 patients on ceralasertib met their primary and secondary endpoints respectively, however, interpretation is limited due to small numbers of evaluable patients. 1 patient had a grade 3 serious adverse event of chest pain in the ceralasertib arm. There were no unexpected safety findings for either drug and adverse events were generally low grade. The translational data has generated new insights into the immunomodulatory effect of ceralasertib. Further evaluation of the combination of ceralasertib with immune checkpoint blockade is warranted to explore this novel immune mechanism of action. Citation Format: Gemma N. Jones, Sonia Iyer, Marta Milo, Pei-Jen Lou, Melonie A. Nance, Carlos A. Gomez-Roca, Nathan Standifer, Paola Marco-Casanova, Shaan Gill, Michael Surace, Richard Bystry, Maria Alexandrova, Sophie Willis, Jaime Rodriguez-Canales, Andreas Dannhorn, Bienvenu Loembé, Alan Lau, Natalia Lukashchuk, Elizabeth A. Harrington, Elhan Sanai, Emma Dean, Umamaheswar Duvvuri. Immunomodulatory effects of the ATR inhibitor ceralasertib in a window of opportunity biomarker trial in patients with head and neck squamous cell carcinoma [abstract]. In: Proceedings of the American Association for Cancer Research Annual Meeting 2023; Part 2 (Clinical Trials and Late-Breaking Research); 2023 Apr 14-19; Orlando, FL. Philadelphia (PA): AACR; Cancer Res 2023;83(8_Suppl):Abstract nr CT198.
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КАРДАШЕВСКАЯ, В. Н., Г. С. АНИСИМОВА, Е. В. БАДАНИНА, В. М. САВАТЕНКОВ, and А. В. ТРАВИН. "ALGAMA GOLD ORE CLUSTER (ALDAN–STANOVOI SHIELD): MINERALOGY, FORMATION CONDITIONS, SOURCES OF ORE MATTER, AND AGE OF MINERALIZATION." Геология и геофизика 65, no. 3 (2024): 471–95. http://dx.doi.org/10.15372/gig2023175.
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Приведены результаты изучения условий образования руд малоизученного Алгоминского рудного узла (месторождение Бодороно и рудопроявление Дывок), расположенного на сочленении Алданского щита и Становой области. Установлено, что в рудах месторождения Бодороно присутствуют минералы Bi и Se (висмутин, лиллианит, самородный висмут, теллуровисмутит, тетрадимит, хедлейит, пильзенит и лайтакарит). Выделены две последовательные продуктивные стадии минералообразования: Au-полиметаллическая и Au-Bi-Te. Эти минералы являются продуктами эволюции гидротермальной системы, в ходе которой происходило постепенное снижение температур (от 300 до 145 °С) и солености (от 5 до 1.9 мас. % NaCl-экв.) флюида. Пробность самородного золота постепенно увеличивается от ранних стадий (~840 ‰) к поздним (~940 ‰), и происходит смена от простых сульфидов до сульфосолей. Установлено изменение состава газовой фазы флюидных включений от CH4–CO2 до преимущественно CO2 с примесью N2 и CH4 по мере развития рудной системы. Результаты 40Ar/39Ar датирования предрудных метасоматитов свидетельствуют о развитии рудообразующих процессов на месторождении Бодороно около 150 ± 1.8 млн лет назад. Анализ изотопного состава свинца в галенитах говорит о доминирующей роли древнекорового источника рудного вещества. Рассчитанный состав изотопов кислорода δ18OH2O в рудоносных кварцах варьирует от 1.0 до 7.3 ‰, что соответствует водному флюиду смешанного источника. Рудопроявление Дывок отличается от месторождения Бодороно по минеральному составу руд и по физико-химическим параметрам рудообразования. На рудопроявлении выделены четыре минеральные стадии: золото-арсенопирит-пирит-кварцевая, пирит-халькопирит-сфалеритовая, кварц-буланжеритовая и теллуридная. Последняя представлена гесситом, алтаитом, волынскитом, меренскиитом, мелонитом и раклиджитом. Золотоносное оруденение формировалось из флюида с умеренно концентрированной соленостью (0.9—9.2 мас. % NaCl-экв.) при среднетемпературных условиях (310—360 °C) с преобладающим присутствием СО2 и примесью СН4 в газовой фазе. Рассчитано, что величины δ34S и δ18O изменялись от 2.2 до 3.0 ‰ и от 0.6 до 12.0 соответственно. Возраст золотого оруденения (40Ar/39Ar) составляет 124.0 ± 1.5 млн лет, что соответствует этапу тектономагматической активизации Алданского щита. The paper presents results of research into the conditions of formation of ores in the poorly studied Algama ore cluster (Bodorono deposit and Dyvok ore occurrence) located at the junction of the Aldan Shield and the Stanovoi area. We have established that Bi and Se minerals (bismuthinite, lillianite, native bismuth, tellurobismuthite, tetradymite, hedleyite, pilsenite, and laitakarite) are present in the ores of the Bodorono deposit. Two successive productive stages of mineral formation have been distinguished: Au–polymetallic and Au–Bi–Te. The corresponding minerals are products of the evolution of a hydrothermal system, during which a gradual decrease in fluid temperature (from 300 to 145 °C) and salinity (from 5 to 1.9 wt.% NaCl equiv.) took place. The fineness of native gold gradually increases from early (~840‰) to late (~940‰) stages and changes in passing from simple sulfides to sulfosalts. The evolution of the ore system is accompanied by a change in the composition of the vapor phase of fluid inclusions from CH4–CO2 to CO2 with an impurity of N2 and CH4. The results of 40Ar/39Ar dating of pre-ore metasomatites point to ore-forming processes at the Bodorono deposit ca. 150 ± 1.8 Ma. Analysis of the isotopic composition of lead in galena shows the leading role of the ancient crustal source of ore matter. The calculated isotopic composition of oxygen (δ18OH2O) in ore-bearing quartz varies from 1.0 to 7.3‰, which corresponds to an aqueous fluid of a mixed source. The Dyvok ore occurrence differs from the Bodorono deposit in the mineral composition of ores and the physicochemical parameters of ore formation. Four mineral stages have been established within the ore occurrence: gold–arsenopyrite–pyrite–quartz, pyrite–chalcopyrite–sphalerite, quartz–boulangerite, and telluride. The telluride stage is represented by hessite, altaite, volynskite, merenskyite, melonite, and rucklidgeite. Gold-bearing mineralization formed from a fluid of medium salinity (0.9–9.2 wt.% NaCl equiv.) with a predominance of CO2 and an impurity of CH4 in the vapor phase at moderate temperatures (310–360 °C). The calculated values of δ34S and δ18O varied from 2.2 to 3.0‰ and from 0.6 to 12.0‰, respectively. The 40Ar/39Ar age of gold mineralization is 124.0 ± 1.5 Ma, which corresponds to the stage of tectonomagmatic activity in the Aldan Shield.
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Hanagata, S., and T. Nobuhara. "Illustrated guide to Pliocene foraminifera from Miyakojima, Ryukyu Island Arc, with comments on biostratigraph." Palaeontologia Electronica 33, no. 8 (2015): 1–142. https://doi.org/10.26879/444.
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Hanagata, S, Nobuhara, T (2015): Illustrated guide to Pliocene foraminifera from Miyakojima, Ryukyu Island Arc, with comments on biostratigraph. Palaeontologia Electronica (Cambridge, England) 33 (8): 1-142, DOI: 10.26879/444, URL: http://dx.doi.org/10.26879/444
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Ma, M., A. Santosa, K. O. Kong, et al. "POS0200 POST-mRNA VACCINE FLARES IN AUTOIMMUNE INFLAMMATORY RHEUMATIC DISEASES: INTERIM RESULTS FROM THE CORONAVIRUS NATIONAL VACCINE REGISTRY FOR IMMUNE DISEASES SINGAPORE (CONVIN-SING)." Annals of the Rheumatic Diseases 81, Suppl 1 (2022): 333–34. http://dx.doi.org/10.1136/annrheumdis-2022-eular.1787.
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BackgroundPublished data suggest no increased rate of flare of autoimmune inflammatory rheumatic diseases (AIIRD) after COVID-19 mRNA vaccination; however, the studies are limited by small sample size, short follow up or at risk of selection bias (voluntary physician reports or patient surveys).ObjectivesTo study flares of AIIRD within three months of the first dose of an anti-SARS-COV2 mRNA vaccine.MethodsA retrospective cohort study of consecutive AIIRD patients ≥ 12 years old, across six public hospitals in Singapore who received at least one dose of an mRNA (Pfizer/BioNTech or Moderna) vaccine. Data were censored at the first post-vaccine clinic visit when the patient had flared or if ≥ three months had elapsed since the first dose of the vaccine, whichever came first. Predictors of flare were determined by Cox proportional hazards analysis and time to flare was examined using a Nelson Aalen cumulative hazard estimate (Figure 1).Figure 1.Nelson-Aalen curve of flares over timeResults2339 patients (74% Chinese, 72% female) of median (IQR) age 64 (53, 71) years were included in the interim analysis (Table 1). 2112 (90%) had the Pfizer/BioNTech vaccine and 195 (8%) had Moderna, with a median (IQR) interval of 21 (21, 23) days between the two doses. The most common AIIRD diagnoses were Rheumatoid arthritis (1063, 45%), Psoriatic arthritis (296, 12.6%) and Systemic lupus erythematosus (SLE) (288, 12.3%). 186 (8%) were treated with biologics/ targeted disease modifying agents. 2125 (91%) patients were in low disease activity or remission. Treatment was interrupted for vaccination in only 18 (0.8%) patients. Seven (0.3%) patients had previous COVID-19 infection.Table 1.Patient characteristicsBaseline characteristicsNo flares(n = 1887, %)Flares within 0—3 months of 1st vaccine dose (n= 272, %)Flares outside of 0 – 3 months after 1st vaccine dose (n = 180, %)Age (median years, IQR)64 (53, 71)61 (50, 69)65 (55, 71)RaceChinese1386 (73)206 (76)129 (72)Malay193 (10)28 (10)20 (11)Indian195 (10)27 (10)26 (14)GenderFemale1367 (72)200 (74)117 (65)Vaccine typePfizer/BioNTech1713 (92)239 (90)160 (90)Moderna149 (8)28 (10)18 (10)DiagnosisRheumatoid Arthritis831 (44)139 (51)93 (52)Systemic Lupus Erythematosus269 (14)20 (7)9 (5)Psoriatic Arthritis225 (12)42 (15)29 (16)Spondyloarthropathies141 (7)21 (7)17 (9)Sjogren’s Syndrome114 (6)15 (6)8 (4)Systemic sclerosis94 (5)4 (1)6 (3)Baseline Physician Disease ActivityRemission1007 (53)99 (36)63 (35)Low Disease Activity731 (39)128 (47)97 (54)Moderate Disease Activity134 (7)40 (15)20 (11)High Disease Activity15 (1)5 (2)0452 (19%) flares were recorded during 9798.8 patient-months [4.6/100 patient-months, median (IQR) follow up duration 4.2 (3.3, 5.3) months], of which 272 (11.6%) patients flared within the 3-month period of interest and 180 (7.7%) flared outside of the 3-month period (Table 1). Median (IQR) time-to-flare was 40.5 (18, 56.6) days. 60 (22.1%) were mild and self-limiting, 170 (62.5%) were mild-moderate and 42 (15.4%) were severe. 190 (69.8%) of those who flared required escalation of treatment and 15 (5.5%) required hospital admission. 239 (10.2%) had improved disease activity after the vaccine.On multivariate Cox regression analysis, patients in the oldest age tertile [median (IQR) 74 (71, 79) years] were less likely to flare [HR 0.80 (95% CI 0.63, 1.00), p = 0.05] Patients with inflammatory arthritis (compared with connective tissue disease, vasculitis and others) and patients with baseline active disease were more likely to flare [HR 1.72 (95% CI 1.35, 2.20), p < 0.001 and 1.82 (95% CI 1.39, 2.39), p < 0.001 respectively]ConclusionThere was a moderately high rate of AIIRD flares after mRNA vaccination; however, there was no clustering of flares in the immediate post-vaccine period to suggest causality. Older patients were less likely to flare, while those with inflammatory arthritis and active disease at baseline were more likely to flare.Disclosure of InterestsMargaret Ma Grant/research support from: Support grant from multiple companies for the Singapore Biologics registry, Amelia Santosa Speakers bureau: Amgen Talk, Consultant of: Pfizer ad board, Kok Ooi Kong: None declared, Chuanhui Xu: None declared, Johnston Tang Gin Xiang: None declared, Gim Gee Teng Speakers bureau: Boehringer Ingleheim, Anselm Mak Speakers bureau: J&J and GSK, Grant/research support from: GSK - the supported studies programme, Sen Hee Tay: None declared, Victoria Wei Wen Ng: None declared, Joshua Zhi En Koh: None declared, Warren Fong Speakers bureau: speaker for Abbvie, DKSH, GSK, Novartis, Li-Ching Chew Speakers bureau: pfizer and Abbvie, Consultant of: Pfizer and Abbvie Advisory Board meeting, Grant/research support from: Abbvie educational grant for ultrasound conference, Andrea Low Speakers bureau: Boehringer Ingeilheim, Consultant of: Consultant/steering group committee for BI and J&J, annie law: None declared, Yih Jia Poh: None declared, Siaw Ing Yeo Grant/research support from: Multiple pharmaceutical companies for the support of the National Biologics Registry, Ying Ying Leung Speakers bureau: Abbvie, DKSH, Jassen, Novartis and Pfizer, Wei-Rui Goh: None declared, Chuah Tyng Yu: None declared, Nur Emillia Roslan: None declared, Stanley Angkodjojo Speakers bureau: Boehringer Ingeilheim, Consultant of: Abbvie and DKSH, Kee Fong Phang: None declared, Thaschawee Arkachaisri: None declared, Melonie Sriranganathan: None declared, Teck Choon TAN: None declared, Peter Cheung Consultant of: Ad board for Boehringer Ingleheim, novartis, janssen and abbvie, Grant/research support from: Novartis, Manjari Lahiri Speakers bureau: J&J, DSKH, Consultant of: DSKH, Gilead, Grant/research support from: Multiple pharma companies contributed to the Singapore Biologics registryNovartis
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Matsuyuki, Yoe, Nariyoshi Umekubo, and Satoshi Yokoshima. "Total Synthesis of Melonine." Organic Letters, February 22, 2025. https://doi.org/10.1021/acs.orglett.4c04851.
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TORUN, Ayşe, and Önder TÜRKMEN. "Bazı Kavun Genotiplerinde Arbuscular Mikorhizal Fungus (AMF) Uygulamalarının Fusarium oxysporum f.sp. melonis’e Dayanıklılık Düzeylerine Etkileri." Journal of the Institute of Science and Technology, June 30, 2018, 17–22. http://dx.doi.org/10.21597/jist.427834.
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Sari, Ni Kadek Yunita, Anak Agung Ayu Putri Permatasari, Ni Putu Widya Astuti, and Dylla Hanggaeni Dyah Puspaningrum. "INTRODUKSI PENANGANAN PASCA PANEN PANDAN WANGI PADA KELOMPOK TANI MILENIAL DI DESA CEPAKA, KEDIRI TABANAN." Seminar Nasional Aplikasi Iptek (SINAPTEK) 3 (December 17, 2020). http://dx.doi.org/10.36002/sptk.v0i0.1214.
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ABSTRAKSalah satu perkebunan pandan wangi di Bali adalah kelompok tani milenial mengusung nama UD Melonila, yang terletak di Jalan Raya Munggu Kapal, Banjar Batanduren Desa Cepaka, Kediri, Tabanan, Bali. Sejauh ini penanganan pasca panen daun pandan wangi hanya dilakukan dengan memangkas daun kemudian dijual ke pengepul, dan sebagian dibeli oleh pedagang canang yang ada di kawasan tersebut. Penanganan pasca panen dengan mengolah daun pandan wangi menjadi produk yang memiliki nilai jual yang lebih tinggi belum pernah dilakukan. Permasalahan mitra: 1) Mitra belum mengetahui teknologi pasca panen daun pandan wangi yang tepat untuk menghasilkan suatu produk dengan daya jual yang lebih tinggi 2) Mitra belum memiliki pengetahuan tentang simplisia dan metode pengolahan daun pandan wangi menjadi simplisia. Solusi yang ditawarkan yaitu 1)Sosialisasi melalui penyuluhan tentang pengenalan produk simplisia, 2)Sosialisasi melalui penyuluhan tentang definisi simplisia, kegunaan dan metode pengolahan daun pandan wangi menjadi simplisia. Hasil yang didapatkan yaitu; 1)Tingkat pengetahuan mitra meningkat dari tidak tahu menjadi tahu akan pengembangan produk simplisia; 2)Semua anggota Mitra yang mengikuti sosialisasi mendapatkan rerata nilai pemahaman 84 pada post-test.Kata Kunci : Desa Cepaka, Kelompok Tani Milenial, Simplisia, Pandan Wangi
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Kardashevskaia, V. N., G. S. Anisimova, E. V. Badanina, V. M. Savatenkov, and A. V. Travin. "Algama Gold Ore Cluster (Aldan–Stanovoi Shield): Mineralogy, Formation Conditions, Sources of Ore Matter, and Age of Mineralization." Russian Geology and Geophysics, December 12, 2023. http://dx.doi.org/10.2113/rgg20234618.
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Abstract —The paper presents results of research into the conditions of formation of ores in the poorly studied Algama ore cluster (Bodorono deposit and Dyvok ore occurrence) located at the junction of the Aldan Shield and the Stanovoi area. We have established that Bi and Se minerals (bismuthinite, lillianite, native bismuth, tellurobismuthite, tetradymite, hedleyite, pilsenite, and laitakarite) are present in the ores of the Bodorono deposit. Two successive productive stages of mineral formation have been distinguished: Au–polymetallic and Au–Bi–Te. The corresponding minerals are products of the evolution of a hydrothermal system, during which a gradual decrease in fluid temperature (from 300 to 145 °C) and salinity (from 5 to 1.9 wt.% NaCl equiv.) took place. The fineness of native gold gradually increases from early (~840‰) to late (~940‰) stages and changes in passing from simple sulfides to sulfosalts. The evolution of the ore system is accompanied by a change in the composition of the vapor phase of fluid inclusions from CH4–CO2 to CO2 with an impurity of N2 and CH4. The results of 40Ar/39Ar dating of pre-ore metasomatites point to ore-forming processes at the Bodorono deposit ca. 150 ± 1.8 Ma. Analysis of the isotopic composition of lead in galena shows the leading role of the ancient crustal source of ore matter. The calculated isotopic composition of oxygen (δ18OH2O) in ore-bearing quartz varies from 1.0 to 7.3‰, which corresponds to an aqueous fluid of a mixed source. The Dyvok ore occurrence differs from the Bodorono deposit in the mineral composition of ores and the physicochemical parameters of ore formation. Four mineral stages have been established within the ore occurrence: gold–arsenopyrite–pyrite–quartz, pyrite–chalcopyrite–sphalerite, quartz–boulangerite, and telluride. The telluride stage is represented by hessite, altaite, volynskite, merenskyite, melonite, and rucklidgeite. Gold-bearing mineralization formed from a fluid of medium salinity (0.9–9.2 wt.% NaCl equiv.) with a predominance of CO2 and an impurity of CH4 in the vapor phase at moderate temperatures (310–360 °C). The calculated values of δ34S and δ18O varied from 2.2 to 3.0‰ and from 0.6 to 12.0‰, respectively. The 40Ar/39Ar age of gold mineralization is 124.0 ± 1.5 Ma, which corresponds to the stage of tectonomagmatic activity in the Aldan Shield.