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Journal articles on the topic 'Membrane plasmapheresis'

Author: Grafiati

Published: 2 June 2025

Last updated: 31 July 2025

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1

POPOVICH, ROBERT, ZENGZHI HE, and JACK MONCRIEF. "Peritoneal Membrane Plasmapheresis." ASAIO Journal 38, no. 3 (1992): M668—M672. http://dx.doi.org/10.1097/00002480-199207000-00121.

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2

Nosé, Y., and P. S. Malchesky. "Therapeutic Membrane Plasmapheresis." Therapeutic Apheresis 4, no. 1 (2000): 3–9. http://dx.doi.org/10.1046/j.1526-0968.2000.00231.x.

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3

Popovich, Robert, Zengzhi He, and Jack Moncrief. "Peritoneal Membrane Plasmapheresis." Peritoneal Dialysis International: Journal of the International Society for Peritoneal Dialysis 13, no. 2_suppl (1993): 82–84. http://dx.doi.org/10.1177/089686089301302s20.

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4

Lambrecht, L., R. Vanholder, and S. Ringoir. "Single-Needle Membrane Plasmapheresis." Blood Purification 6, no. 2 (1988): 77–84. http://dx.doi.org/10.1159/000169487.

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5

Baldini, G. M., E. Baldini, and M. De Palma. "Donor Plasmapheresis: Plasma Membrane Separators." International Journal of Artificial Organs 16, no. 5_suppl (1993): 143–44. http://dx.doi.org/10.1177/039139889301605s29.

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6

McVey, D. Scott, and Raymond W. Loan. "Total and antigen-specific serum immunoglobulin isotype concentrations in hyperimmunized cattle that have undergone plasmapheresis." American Journal of Veterinary Research 50, no. 5 (1989): 758–61. https://doi.org/10.2460/ajvr.1989.50.05.758.

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SUMMARY The effects of prolonged plasmapheresis of cattle on total and antigen-specific immunoglobulin production were evaluated. Five adult cows were hyperimmunized by repeated iv administration of live, logarithmic-phase Pasteurella haemolytica A1 organisms. Three of the cows underwent plasmapheresis daily for 3 weeks. From 2 cows, serum was only obtained periodically. Anti-P haemolytica antibody was assayed by indirect hemagglutination and a kinetic-augmented, antigen-capture elisa for capsular polysaccharide and lipopolysaccharide/outer membrane protein antigens. Total serum immunoglobulin

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7

Stepner, Tova A., Christian S. Vassilieff, and Edward F. Leonard. "Cell-plasma interactions during membrane plasmapheresis." Clinical Hemorheology and Microcirculation 5, no. 1 (2016): 15–26. http://dx.doi.org/10.3233/ch-1985-5104.

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8

Yokoyama, Shigeki, Retsuji Yamanaka, Manabu Oki, and Takemitsu Hosoi. "Donor plasmapheresis using automated membrane devices." Journal of the Japan Society of Blood Transfusion 36, no. 1 (1990): 5–9. http://dx.doi.org/10.3925/jjtc1958.36.5.

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9

Faber, J. C., A. J. Reppucci, J. M. Mathias, and J. P. Hoffmann. "Automated plasmapheresis with a nylon membrane." Plasma Therapy and Transfusion Technology 9, no. 4 (1988): 347–50. http://dx.doi.org/10.1016/0278-6222(88)90013-7.

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10

Stromberg, R. R., L. I. Friedman, D. R. Boggs, and M. J. Lysaght. "Membrane technology applied to donor plasmapheresis." Journal of Membrane Science 44, no. 1 (1989): 131–43. http://dx.doi.org/10.1016/s0376-7388(00)82345-5.

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11

YOKOYAMA, MASAKAZU, and HIROSHI TSUDA. "Changes in bradykinin by membrane plasmapheresis." Juntendo Medical Journal 40, no. 2 (1994): 183–88. http://dx.doi.org/10.14789/pjmj.40.183.

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12

Sinha, Aditi, Anand Narain Tiwari, Rahul Chanchlani, V. Seetharamanjaneyulu, Pankaj Hari, and Arvind Bagga. "Therapeutic Plasmapheresis using Membrane Plasma Separation." Indian Journal of Pediatrics 79, no. 8 (2012): 1084–86. http://dx.doi.org/10.1007/s12098-012-0779-8.

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13

Karakus, Volkan, Burak Deveci, and Erdal Kurtoğlu. "Treatment of plasmapheresis refractory thrombotic thrombocytopenic purpura with double-filtration membrane plasmapheresis." Transfusion and Apheresis Science 48, no. 3 (2013): 313–14. http://dx.doi.org/10.1016/j.transci.2013.04.006.

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14

Liubchak, Vladislav V., Liliia M. Khomenko, Michael P. Kovalishyn, et al. "MEDICAL AND ECONOMIC ANALYSIS OF THE CHOICE OF THERAPEUTIC PLASMAPHERESIS METHOD TO OPTIMIZE THE TRANSFUSION CARE QUALITY." Wiadomości Lekarskie 74, no. 10 (2021): 2466–70. http://dx.doi.org/10.36740/wlek202110119.

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The aim: To analyze the medical and economic aspects of the manual and different types of automatic plasmapheresis (manual, automatic centrifugal, automatic membrane, plasmapheresis with plasma therapy and mixed) used for therapeutic purposes. Materials and methods: The Baxter Auto-C, Haemonetics PCS2, Haemophenics, Baxter CPDA anticoagulant and saline, Baxter 16GA needles were used. Total protein was examined by the biuret method, hemoglobin by the Sally method, total bilirubin by the colorimetric photometric method, cell fragments by the Goryaev camera microscopy method; patient comfort – wi

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15

Siami, G. A., and F. S. Siami. "COMPLICATIONS OF SECONDARY ON-LINE MEMBRANE PLASMAPHERESIS." ASAIO Journal 46, no. 2 (2000): 207. http://dx.doi.org/10.1097/00002480-200003000-00227.

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16

Follette, D. B., D. Kerr, T. J. Nasca, H. H. Euler, and A. J. Pinevich. "A method for chronic membrane plasmapheresis in the rat." Journal of Applied Physiology 75, no. 6 (1993): 2820–24. http://dx.doi.org/10.1152/jappl.1993.75.6.2820.

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Therapeutic apheresis as applied to humans may encompass a single treatment or numerous treatments for disorders ranging from acute poisoning to severe chronic autoimmune disease. However, the mechanisms of beneficial effects of apheresis are not well characterized. Utilizing a miniaturized hollow-fiber membrane system, we have developed a reliable technique for long-term vascular access in the rat that permits repetitive plasmapheresis. We established vascular access in 14 animals, with 8 and 6 rats randomized to 3- and 7-wk experimental periods, respectively. Immunoglobulin levels of blood s

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17

Sukhanov, A. A. Tarabrin O. A. Kirpichnikova E. P. Zukow W., A. A. Tarabrin O. A. Kirpichnikova E. P. Zukow W. Sukhanov, A. A. Tarabrin O. A. Kirpichnikova E. P. Zukow W. Sukhanov та A. A. Tarabrin O. A. Kirpichnikova E. P. Zukow W. Sukhanov. "Efficacy of membrane plasmapheresis in patients with opioid addiction = Эффективность применения мембранного плазмафереза у больных опийной наркоманией". Journal of Health Sciences 4, № 14 (2014): 91–100. https://doi.org/10.5281/zenodo.13311.

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<strong>Sukhanov A A, Tarabrin O A, Kirpichnikova E P, Zukow W. Efficacy of membrane plasmapheresis in patients with opioid addiction = </strong><strong>Эффективность</strong> <strong>применения</strong> <strong>мембранного</strong> <strong>плазмафереза</strong> <strong>у</strong> <strong>больных</strong> <strong>опийной</strong> <strong>наркоманией</strong><strong>. </strong><strong>Journal of Health Sciences. 2014;4(14):91-100. ISSN 1429-9623 / 2300-665X.</strong> <strong>http://journal.rsw.edu.pl/index.php/JHS/article/view/2014%3B4%2814%29%3A91-100</strong> <strong>http://ojs.ukw.edu.pl/ind

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18

Redant, Sebastien, David De Bels, Khalid Ismaili, and Patrick M. Honoré. "Membrane-Based Therapeutic Plasma Exchange in Intensive Care." Blood Purification 50, no. 3 (2020): 290–97. http://dx.doi.org/10.1159/000510983.

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19

Sokolov, Ye I., S. V. Podachina, V. I. Zabotnov, and Ye B. Zanina. "Usage of plasmapheresis in combined therapy of diabetics." Problems of Endocrinology 40, no. 5 (1994): 13–16. http://dx.doi.org/10.14341/probl12158.

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Clinical observations have repeatedly proved that myocardial infarction in patients with diabetes mellitus (DM) is much more difficult, gives greater mortality, its complications such as acute heart failure, arrhythmia, and relapses are more often observed. The basis of the atherosclerotic process both in diabetes and without it, the main place is given to hyperlipoproteinemia (hypercholesterolemia, hypertriglyceridemia and hypoalpha-cholesterolemia). Most patients with severe type I diabetes mellitus (insulin-dependent, IDDM) and type II diabetes mellitus (non-insulin-dependent, NIDDM) showed

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20

Kim, Su Wan, and Kyoung Hee Han. "The combination therapy with extracorporeal membrane oxygenation, plasmapheresis and continuous renal replacement therapy for massive diffuse alveolar hemorrhage in a child with systemic lupus erythematosus." Journal of Medicine and Life Science 14, no. 1 (2017): 35–38. http://dx.doi.org/10.22730/jmls.2017.14.1.35.

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Diffuse alveolar hemorrhage (DAH) is a rare and life-threatening complication in children with systemic lupus erythematosus(SLE). Despite recent advances in medical therapy, DAH could drive into catastrophic respiratory failure and hemodynamicunstability. The authors present a case of a 9-year-old girl with lupus nephritis who had rapidly aggravating dyspnea andmassive pulmonary hemorrhage. She was diagnosed as having DAH with acute respiratory distress syndrome and wassuccessfully managed with combined treatment of venovenous extracorporeal membrane oxygenation (ECMO), plasmapheresis,and cont

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21

Vassilieff, Christian S., Edward F. Leonard, and Tova A. Stepner. "The mechanism of cell rejection in membrane plasmapheresis." Clinical Hemorheology and Microcirculation 5, no. 1 (2016): 7–14. http://dx.doi.org/10.3233/ch-1985-5103.

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22

Omokawa, S., P. S. Malchesky, M. Yamashita, et al. "Effect of Anticoagulant on Biocompatibility in Membrane Plasmapheresis." International Journal of Artificial Organs 13, no. 11 (1990): 768–77. http://dx.doi.org/10.1177/039139889001301110.

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23

Opatrný, K., V. Spustová, Z. Rusavý, K. Opatrný, J. Eiselt, and A. Válek. "Membrane Plasmapheresis Raises the Serum Concentrations of Pseudouridine." International Journal of Artificial Organs 14, no. 5 (1991): 313–15. http://dx.doi.org/10.1177/039139889101400512.

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24

HOSOKAWA, SHINICHI, ATSUSHI OYAMACUCHI, and OSAMU YOSHIDA. "Successful Immunoadsorption with Membrane Plasmapheresis for Multiple Sclerosis." ASAIO Transactions 35, no. 3 (1989): 576–77. http://dx.doi.org/10.1097/00002216-198907000-00131.

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25

HOSOKAWA, SHINICHI, ATSUSHI OYAMACUCHI, and OSAMU YOSHIDA. "Successful Immunoadsorption with Membrane Plasmapheresis for Multiple Sclerosis." ASAIO Transactions 35, no. 3 (1989): 576–77. http://dx.doi.org/10.1097/00002480-198907000-00131.

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26

Siami, G. A., and F. S. Siami. "PLASMAPHERESIS USING SECONDARY MEMBRANE FILTERS: 12 YEARS EXPERIENCE." ASAIO Journal 45, no. 2 (1999): 193. http://dx.doi.org/10.1097/00002480-199903000-00287.

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27

Profitt, Tim W., and John M. Radovich. "Electrophoretic Control of Concentration Polarization in Membrane Plasmapheresis." Artificial Organs 10, no. 1 (1986): 52–58. http://dx.doi.org/10.1111/j.1525-1594.1986.tb02516.x.

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28

Gupta, Kanupriya. "Plasmapheresis in Management of Oral Autoimmune Disorders." Journal of Drug Delivery and Therapeutics 9, no. 3 (2019): 658–60. http://dx.doi.org/10.22270/jddt.v9i3.2905.

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Systemic autoimmune diseases based on an immune pathogenesis produce autoantibodies and circulating immune complexes, which cause inflammation in the tissues of various organs. In most cases, these diseases have a bad prognosis without treatment. Autoimmune disorders are a group of poorly understood diseases in which the body fails to distinguish between self and non- self which could result in damage to the self. Oral mucous membrane may be affected by a variety of autoimmune mucocutaneous diseases such as pemphigus, bullous pemphigoid, mucous membrane pemphigoid, lichen planus, erythema mult

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29

Marlu, Raphaël, Hamza Naciri Bennani, Landry Seyve, et al. "Comparison of three modalities of plasmapheresis on coagulation: Centrifugal, single‐membrane filtration, and double‐filtration plasmapheresis." Journal of Clinical Apheresis 36, no. 3 (2021): 408–19. http://dx.doi.org/10.1002/jca.21879.

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30

Konca, Capan, Ayse B. Anil, Onur Isik, et al. "The First Case of Multisystem Inflammatory Syndrome in Children Successfully Treated with Combined Therapies Including Extracorporeal Membrane Oxygenation and Plasmapheresis." Journal of Pediatric Infectious Diseases 17, no. 01 (2021): 053–58. http://dx.doi.org/10.1055/s-0041-1739393.

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AbstractMultisystem inflammatory syndrome in children (MIS-C) is a severe disease that can lead to death. There is no definitive treatment for MIS-C yet. It has been reported that intravenous immunoglobulin, intravenous methylprednisolone, fluid supplements, antibiotics, inotropics, extracorporeal membrane oxygenation (ECMO), plasmapheresis, biological therapy, and anticoagulation therapy can be used for treatment. In this article, we presented an 8-year-old girl child patient who survived due to timely administered ECMO and combined therapies including plasmapheresis without any sequela despi

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31

Naganuma, Shinji, Jyun Murakami, Hiroyuki Arai, Kazuyuki Matsumoto, Motokazu Matsuoka, and Tetsuzo Agishi. "Safety confirmation of membrane plasmapheresis for a donation purpose." Journal of the Japan Society of Blood Transfusion 34, no. 1 (1988): 53–58. http://dx.doi.org/10.3925/jjtc1958.34.53.

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32

Murabayashi, Shun, Susumu Omokawa, Tetsuro Takaoka, Paul S. Malchesky, and Yukihiko Nosé. "Biocompatibility in Membrane Plasmapheresis: The Necessity of Global Understanding." Therapeutic Apheresis 4, no. 2 (2000): 173–82. http://dx.doi.org/10.1046/j.1526-0968.2000.004002173.x.

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33

Euler, Hans H., Uwe Krey, Oltmann Schröder, and Helmut Löffler. "Membrane plasmapheresis technique in rats. Confirmation of antibody rebound." Journal of Immunological Methods 84, no. 1-2 (1985): 313–19. http://dx.doi.org/10.1016/0022-1759(85)90438-7.

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34

Burnouf, Thierry, Michel Eber, Daniel Kientz, Jean-Pierre Cazenave, and Thomas Burkhardt. "Assessment of complement activation during membrane-based plasmapheresis procedures." Journal of Clinical Apheresis 19, no. 3 (2004): 142–47. http://dx.doi.org/10.1002/jca.20019.

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35

Reding, R., D. J. G. White, H. ff S. Davies, and R. Y. Calne. "Plasma exchange technique in the unheparinized, unanaesthetized rat." Laboratory Animals 22, no. 4 (1988): 293–96. http://dx.doi.org/10.1258/002367788780746160.

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An inexpensive and convenient plasma exchange technique has been developed in the rat, which avoids heparin and membrane plasmapheresis technology. The use of a reliable venous vascular access on unanaesthetized, briefly restrained animals is described.

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36

Haris, Ágnes, József Arányi, Henrik Braunitzer, et al. "Role of plasmapheresis in immunological kidney diseases. Experience from 1050 completed plasmapheresis treatment sessions." Orvosi Hetilap 152, no. 28 (2011): 1110–19. http://dx.doi.org/10.1556/oh.2011.29155.

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Plasmapheresis is an effective treatment modality in several immunological kidney diseases. It is also indicated in certain neurological and hematological abnormalities, and some other diseases. Aims: In this study the indications and outcomes of the plasma exchange treatments performed in the Plasmapheresis Unit of the authors during the last 12 years are summarized, and the findings are compared to those published in the literature. The procedure, mechanisms of action and adverse effects are also briefly discussed. Methods: Between 1999 and 2010 authors completed 1050 plasma exchanges in 195

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37

Fonseka, C. L., and S. Lekamwasam. "Role of Plasmapheresis and Extracorporeal Membrane Oxygenation in the Treatment of Leptospirosis Complicated with Pulmonary Hemorrhages." Journal of Tropical Medicine 2018 (December 2, 2018): 1–8. http://dx.doi.org/10.1155/2018/4520185.

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Introduction. Leptospirosis is an emerging infectious disease associated with multiorgan involvement and significant morbidity and mortality. Although pulmonary hemorrhage due to leptospirosis has a high fatality, specific treatment options are limited and their efficacy is not adequately proven. We opted to find out the current evidence on plasmapheresis and extracorporeal membrane oxygenation (ECMO) in pulmonary hemorrhages due to leptospirosis. Methods. The first search was conducted in PubMed, OVID, Google Scholar, and Cochrane clinical trial registry using keywords “leptospirosis” OR “Lep

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38

Charcosset, Catherine. "A Review on Membranes for Clinical Treatment and Drug Delivery in Medical Applications." International Journal of Membrane Science and Technology 3, no. 1 (2016): 22–38. http://dx.doi.org/10.15379/ijmst.v3i1.579.

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Membrane processes are used extensively in biomedical applications. This state of the art review presents the main applications including renal kidney, blood filtration, blood oxygenator, artificial liver, artificial pancreas, and drug delivery devices. For well-established treatments like dialysis, plasmapheresis, and blood oxygenator, the techniques are summarized by presenting membranes used, devices, configurations and treatments. The artificial liver and the artificial pancreas are not clinically used and some main aspects related to the development of these devices are given, including c

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39

Maclaren, G., W. Butt, P. Cameron, A. Preovolos, R. Mcegan, and S. Marasco. "Treatment of Polypharmacy Overdose with Multimodality Extracorporeal Life Support." Anaesthesia and Intensive Care 33, no. 1 (2005): 120–23. http://dx.doi.org/10.1177/0310057x0503300118.

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A 45-year-old woman presented to the emergency department of a tertiary referral hospital after taking an overdose of verapamil, doxepin, quetiapine, diazepam, temazepam, and clonazepam. She rapidly developed shock refractory to pharmacological support and was placed on percutaneous venoarterial extracorporeal membrane oxygenation (ECMO). She had a severe metabolic acidosis from a combination of shock and drug intoxication that improved with continuous venovenous haemodialysis. Forty-eight hours after presentation, while still on ECMO, the patient had complete cardiac standstill for three and

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40

Yokoyama, Shigeki, and Takemitsu Hosoi. "Donor plasmapheresis using an automated device with polyethylene membrane filtration." Journal of the Japan Society of Blood Transfusion 35, no. 6 (1989): 611–15. http://dx.doi.org/10.3925/jjtc1958.35.611.

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41

Siami, Flora S., and Ghodrat A. Siami. "Plasmapheresis by Using Secondary Membrane Filters: Twelve Years of Experience." ASAIO Journal 46, no. 4 (2000): 383–88. http://dx.doi.org/10.1097/00002480-200007000-00003.

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42

Gautam, S. K., S. Jindal, C. Kudva, and S. Basu. "Exploiting temperature dependence to improve selectivity in membrane-based plasmapheresis." Transfusion Science 16, no. 2 (1995): 173–78. http://dx.doi.org/10.1016/0955-3886(95)97399-k.

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43

v. Baeyer, Hans, Frank Kochinke, and Rainer Schwerdtfeger. "Cascade plasmapheresis with online membrane regeneration: Laboratory and clinical studies." Journal of Membrane Science 22, no. 2-3 (1985): 297–315. http://dx.doi.org/10.1016/s0376-7388(00)81288-0.

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44

Relia, Nitin, Yusra Cheema, Jennifer Tuazon, and James Paprello. "Plasmapheresis in antiglomerular basement membrane disease: How much is enough?" Clinical Nephrology 85 (2016), no. 03 (2016): 189–90. http://dx.doi.org/10.5414/cn108529.

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45

Mineshima, Michio, Tetsuzo Agishi, Kazuo Ota, and Kiyotaka Sakai. "Performance evaluation of disk-type membrane separator for donation plasmapheresis." KAGAKU KOGAKU RONBUNSHU 12, no. 3 (1986): 280–86. http://dx.doi.org/10.1252/kakoronbunshu.12.280.

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46

Pervakova, E. I., V. V. Vasilets, O. N. Rzhevskaya, N. V. Borovkova, and A. V. Pinchuk. "Experience of using polymethyl methacrylate membranes for anti-HLA antibodies’ elimination by hemodialysis in renal transplant recipients." Transplantologiya. The Russian Journal of Transplantation 11, no. 3 (2019): 201–8. http://dx.doi.org/10.23873/2074-0506-2019-11-3-201-208.

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Introduction. In recipients with pre-existing sensitization with incompatible antigens of the main histocompatibility complex, the kidney graft survival after retransplantations directly depends on the level of anti-HLA antibodies. Despite many years of experience in using various methods: plasmapheresis, cascade filtration, immunosorption, intravenous administration of immunoglobulins, the use of polyclonal anti-lymphocytic agents, the search for more acceptable ways to reduce the level of anti-HLA antibodies still remains relevant nowadays.The purpose of the study was to assess the effect of

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47

Armstead, Sumiko I., Thomas Hellmark, Jorgen Wieslander, Xin J. Zhou, Ramesh Saxena, and Nilum Rajora. "A Case of Alport Syndrome with Posttransplant Antiglomerular Basement Membrane Disease despite Negative Antiglomerular Basement Membrane Antibodies by EIA Treated with Plasmapheresis and Intravenous Immunoglobulin." Case Reports in Transplantation 2013 (2013): 1–5. http://dx.doi.org/10.1155/2013/164016.

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Posttransplant antiglomerular basement membrane (anti-GBM) disease occurs in approximately 5% of Alport patients and usually ends in irreversible graft failure. Recent research has focused on characterizing the structure of the anti-GBM alloepitope. Here we present a case of a 22-year-old male with end-stage renal disease secondary to Alport syndrome, with a previously failed renal allograft, who received a second deceased-donor kidney transplant. Six days after transplantation, he developed acute kidney injury. The serum anti-GBM IgG was negative by enzyme immunoassay (EIA). On biopsy, he had

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48

Mirashvili, Marina Ivanovna, Marina Sabirovna Zainulina, Sergey Alekseevich Selkov, and Alexander Mkrtichevich Gzgzyan. "Diskussionnye voprosy vedeniya zhenshchin s antifosfolipidnymi antitelami pri primenenii VRT." Journal of obstetrics and women's diseases 62, no. 3 (2013): 26–33. http://dx.doi.org/10.17816/jowd62326-33.

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There are many controversies in the management antiphospholipid antibodies-positive women undergoing assisted reproductive technologies. Controversial and important is not only the effect of antiphospholipid antibodies (APA) on the success of IVF, but also approaches to the management of this group of women. The aim of this work was to study the prevalence of antiphospholipid antibodies in women with 3 or more IVF failures and effectiveness of IVF in women with APA treatment with membrane plasmapheresis before IVF and intravenous immunoglobulin during IVF. In women with 3 or more IVF implantat

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49

Thitiarchakul, S., S. M. Lal, A. Luger, and G. Ross. "Goodpasture's Syndrome Superimposed on Membranous Nephropathy. A Case Report." International Journal of Artificial Organs 18, no. 12 (1995): 763–65. http://dx.doi.org/10.1177/039139889501801203.

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We describe a patient with idiopathic membranous glomerulopathy who developed acute deterioration in renal function; this was associated with hemoptysis, severe hypertension, and anti-glomerular basement membrane (anti-GBM) antibody in the serum. Despite aggressive therapy with plasmapheresis, cyclophosphamide and prednisone, the patient progressed to end-stage renal failure and is on maintenance hemodialysis.

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50

Saleh, Ahmed Osman, Wajiha Gul, Mohammad Khair Ahmad Ibraheem Hamad, and Emad Naem. "How to Stop a Thyroid Storm When the Liver Is Bad: A Case Report and Literature Review." Journal of the Endocrine Society 5, Supplement_1 (2021): A933—A934. http://dx.doi.org/10.1210/jendso/bvab048.1908.

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Abstract Introduction: Patients with thyroid storm and resistance or contraindications to conventional medications may receive plasmapheresis until they have the definitive therapy. Case Presentation: A 42 years old lady with no past medical history was brought by the EMS with palpitations, shortness of breath, vomiting, and profuse diarrhea. She was found to have an atrial flutter with low blood pressure, received synchronized cardioversion, but unfortunately, she developed ventricular tachycardia, tonic-clonic seizure and went to pulseless electrical activity (PEA). Upon examination, the pat

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