Academic literature on the topic 'Membrane stabilizing; proteinase'

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Journal articles on the topic "Membrane stabilizing; proteinase"

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Olorunnisola, Olubukola Sinbad, Olumide Samuel Fadahunsi, Adewale Adetutu, and Adedoyin Olasunkanmi. "Evaluation of Membrane Stabilizing, Proteinase and Lipoxygenase Inhibitory Activities of Ethanol Extract of Root and Stem of Sphenocentrum jollyanum Pierre." Journal of Advances in Biology & Biotechnology 13, no. 1 (2017): 1–8. https://doi.org/10.9734/JABB/2017/34121.

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<strong>Aim</strong><strong>:</strong> This study aimed at evaluating the anti-inflammatory potential of ethanol extract of the stem and root of <em>Sphenocentrum jollyanum.</em> <strong>Study Design</strong><strong>:</strong> Red blood cell Membrane stabilization, anti-lipoxygenase and proteinase inhibitory activities of the extracts were assayed <em>in-vitro</em> as a measure of anti-inflammatory potential of ethanol extract of root and stem of <em>Sphenocentrum jollyanum </em>Pierre. <strong>Place and Duration of Study</strong><strong>:</strong> All the work was carried out in the Departmen
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Sinbad, Olorunnisola, Fadahunsi Samuel, Adetutu Adewale, and Olasunkanmi Adedoyin. "Evaluation of Membrane Stabilizing, Proteinase and Lipoxygenase Inhibitory Activities of Ethanol Extract of Root and Stem of Sphenocentrum jollyanum Pierre." Journal of Advances in Biology & Biotechnology 13, no. 1 (2017): 1–8. http://dx.doi.org/10.9734/jabb/2017/34121.

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Begum, Shaheen, V. Anitha Kumari, S. K. Arifa Begum, M. Reddemma, K. Tejaswini, and K. Bharathi. "Synthesis and Evaluation of 1,2,4-Triazole Derivatives for Antioxidant, Anti-inflammatory, Cytotoxicity and QSAR Analysis." Asian Journal of Chemistry 35, no. 1 (2022): 194–202. http://dx.doi.org/10.14233/ajchem.2023.26878.

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A series of novel 4-amino-5-substituted-1,2,4-triazole-3-thiol derivatives (B1-B18) were synthesized and characterized by spectral analysis. Equimolar portions of thiocarbohydrazide and different acids (substituted aryl/heteroaryl/aliphatic) were fused to synthesize the title compounds. The compounds were evaluated for cytotoxicity, in vitro anti-inflammatory activity and antioxidant activities. Cytotoxicity studies highlighted B4 (2,4-dichloro analog) as the potent cytotoxic molecule with IC50 value of 20.35 μM against MCF-7 cell line compared to cisplatin (IC50 = 12.06 μM). B4 (2,4-dichloro)
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Adarsh, Bhargava* Ranjeet Singh Kushwah Vijay Singh Kushwah. "Evaluation Of Anti-Inflamation & Memory Enhancing Activity For Some Pharmacological Active Extracts." International Journal of Pharmaceutical Sciences 2, no. 9 (2024): 1326–35. https://doi.org/10.5281/zenodo.13850908.

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It can be stated that the ethanolic extract has beneficial effects in long lasting in membrane stabilizing method, inhibition of protein denaturation method and proteinase model. It also showed a protective effect on inflammation and memory enhancing effect The mechanism may be mediated via the inhibition of prostaglandin synthesis in acute inflammatory reaction as well as inhibition of various lysosomal enzymes in chronic inflammatory responses this, justifies the claim made by Siddha and Ayurveda. The mechanism for the memory enhancing activity may be inhibition of cholinesterase enzymes in
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Ichikawa, H. Travis, Sandeep Chadha, Qian Zhou, and Philip J. Fay. "Contributions of Residues in the 558-Loop of Factor VIIIa A2 Subunit to Interactions with Factor IXa in Factor Xase." Blood 110, no. 11 (2007): 2688. http://dx.doi.org/10.1182/blood.v110.11.2688.2688.

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Abstract The intrinsic factor Xase complex, comprised of the cofactor, factor VIIIa and serine proteinase, factor IXa assembled on a phospholipid membrane, catalyzes the conversion of factor X to factor Xa. Factor VIIIa, a heterotrimer comprised of A1, A2 and A3C1C2 subunits, is labile due to the weak affinity association of the A2 subunit with the A1/A3C1C2 dimer. However, this interaction is partially stabilized by association of factor VIIIa within the Xase complex and likely results from protein-protein interactions between residues in the A2 subunit and protease domain of factor IXa. One
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Deryaabin, Alexander N., Irena M. Dubinina, Elena A. Burakhanova, et al. "Cold tolerance of potato plants transformed with yeast invertase gene." Acta Agrobotanica 57, no. 1-2 (2013): 31–39. http://dx.doi.org/10.5586/aa.2004.003.

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Our study was carried out with potato plants (&lt;i&gt;Solanum tuberosun&lt;/i&gt; L.,cv. Désirée) transformed with the yeast invertase gene under the control of the B33 class I patatin promoter and with the proteinase inhibitor II leader peptide sequence providing for the apoplastic enzyme localization (B33-&lt;i&gt;inv&lt;/i&gt; plants) and with the plants transformed with the reporter gene encoding bb-glucuronidase under the control of the 35S CaMV promoter (control plants). Exposure to 5°C during 6 days caused an increase in invertase activity and sugar content in B33-&lt;i&gt;inv&lt;/i&gt
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"Antioxidant and Anti-inflammatory Activities of Methanolic Pulp Residue Extract of African Star Apple (Chrysophyllum albidum)." Letters in Applied NanoBioScience 13, no. 1 (2024): 35. https://doi.org/10.33263/lianbs131.035.

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This present study evaluated the in vitro antioxidant and anti-inflammatory activities of methanolic pulp extract of C. albidum fruits to determine its use in treatments of oxidative and inflammatory-related conditions. Fresh fruits of C. albidum were sliced and squeezed to expel the juice. Then the pulp residues were dried in an oven for twenty-four hours at 40oC and pulverized. The powdered sample (76.5 g) was extracted in 80% (v/v) methanol for 72 h and filtered. Filtrate was evaporated in vacuo to obtain the methanolic extract. In vitro evaluations of the antioxidant (via 1,1-diphenyl-2-pi
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Singh, Puneet, Yogesh Sharma, and Ashutosh Sharma. "In-Vitro Anti-inflammatory Activity of Methanolic Extract of Convolvulus pluricaulis Choisy." International Journal of Pharmaceutical and Biological Science Archive 9, no. 1 (2021). http://dx.doi.org/10.32553/ijpba.v9i1.175.

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Aim: In-Vitro Anti-inflammatory Activity of Methanolic Extract of Convolvulus pluricaulis Choisy.&#x0D; Material &amp; Methods- The whole plant parts of Convolvulus pluricaulis Choisy were purchased from the local market. Whole plant materials were dried under shade and subjected to coarse powder for extraction process. Accurately weighed quantity of whole plant material was extracted using 95 % methanol by soxhlet apparatus for 72 h. Qualitative chemical tests of methanolic extracts were subjected to various chemical tests to detect various phytoconstituents. Solvent systems ethyl acetate: me
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Ojo, Oluwafemi Adeleke, Akingbolabo Daniel Ogunlakin, Gideon Ampoma Gyebi, et al. "GC-MS chemical profiling, antioxidant, anti-diabetic, and anti-inflammatory activities of ethyl acetate fraction of Spilanthes filicaulis (Schumach. and Thonn.) C.D. Adams leaves: experimental and computational studies." Frontiers in Pharmacology 14 (July 20, 2023). http://dx.doi.org/10.3389/fphar.2023.1235810.

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Introduction: This study aimed to investigate the chemical profile of GC-MS, antioxidant, anti-diabetic, and anti-inflammatory activities of the ethyl acetate fraction of Spilanthes filicaulis leaves (EFSFL) via experimental and computational studies.Methods: After inducing oxidative damage with FeSO4, we treated the tissues with different concentrations of EFSFL. An in-vitro analysis of EFSFL was carried out to determine its potential for antioxidant, anti-diabetic, and anti-inflammatory activities. We also measured the levels of CAT, SOD, GSH, and MDA.Results and discussion: EFSFL exhibited
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Ysselstein, Daniel, Vartika Mishra, George McCabe, and Jean‐Christophe Rochet. "Effect of Stabilizing Alpha Synuclein‐Membrane Interactions on the Protein's Aggregation and Neurotoxicity." FASEB Journal 30, S1 (2016). http://dx.doi.org/10.1096/fasebj.30.1_supplement.518.7.

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Oligomerization of the protein alpha‐synuclein (aSyn) is a critical factor in the onset of both familial and sporadic Parkinson's disease (PD). In healthy individuals aSyn exists in a number of conformations, including a membrane‐bound state that displays resistance to aggregation. How this aggregation‐resistant state is altered is a significant problem in PD research, as a better understanding of the events that initiate aSyn aggregation is critical for designing neuroprotective strategies. We hypothesize that disruption of interactions between aSyn and phospholipid membranes leads to a shift
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Book chapters on the topic "Membrane stabilizing; proteinase"

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Lorch, Mark, and Rebecca Batchelor. "Stabilizing Membrane Proteins in Detergent and Lipid Systems." In Production of Membrane Proteins. Wiley-VCH Verlag GmbH & Co. KGaA, 2011. http://dx.doi.org/10.1002/9783527634521.ch13.

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