Journal articles: 'Mened'

1

Zehler, Ralph P. "“Mene, Mene, Tekel, Upharsin”." Juvenile and Family Court Journal 28, no. 4 (July 30, 2009): 19–27. http://dx.doi.org/10.1111/j.1755-6988.1977.tb01339.x.

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2

Weinberg, Steven. "Mended symmetries." Physical Review Letters 65, no. 10 (September 3, 1990): 1177–80. http://dx.doi.org/10.1103/physrevlett.65.1177.

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3

Spinney, Laura. "Mended Armor." Nature Medicine 15, no. 1 (January 2009): 10–13. http://dx.doi.org/10.1038/nm0109-10.

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4

Anvik, Cecilie Høj, Trond Bliksvær, and Esben S. B. Olesen. "«Gruppen mener»?" Tidsskrift for velferdsforskning 24, no. 01 (March 26, 2021): 21–34. http://dx.doi.org/10.18261/issn.2464-3076-2021-01-03.

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5

Gervasoni, Carlos, and Olga Wornat. "Menem: La Vida Privada (Menem: The Private Life)." Foreign Policy, no. 118 (2000): 173. http://dx.doi.org/10.2307/1149679.

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6

Lempinen, Petri. "Aikuiskoulutuksella menee hyvin?" Aikuiskasvatus 23, no. 4 (December 1, 2003): 332. http://dx.doi.org/10.33336/aik.93526.

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7

Norynberg, Patrick, Isabelle Moulinier, Marc Ratsimba, and Corinne Tixier. "Quelles politiques mener ?" Projet 312, no. 5 (2009): 72. http://dx.doi.org/10.3917/pro.312.0072.

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8

Ploeg, J. D. van der. "Menen en weten." Kind en adolescent 19, no. 3 (September 1998): 222–24. http://dx.doi.org/10.1007/bf03060710.

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9

Hem, Erlend. "Hva mener Legeforeningen?" Tidsskrift for Den norske legeforening 133, no. 10 (2013): 1041. http://dx.doi.org/10.4045/tidsskr.13.0676.

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10

Ross, Caleb J. "Never Fully Mended." American Book Review 34, no. 1 (2012): 24. http://dx.doi.org/10.1353/abr.2012.0204.

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11

Nusseibeh, Lucy. "Le MEND." Lignes 46, no. 1 (2015): 236. http://dx.doi.org/10.3917/lignes.046.0236.

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12

Jackūnas, Žibartas. "Tiesa mene." Problemos 30 (September 29, 2014): 5–15. http://dx.doi.org/10.15388/problemos.1983.30.6427.

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Straipsnyje nagrinėjama meno kūrinio gnoseologinio statuso problema. Aptariami skirtingi požiūriai į meno ir loginio sprendinio santykio problemą, gvildenamas meninės tiesos klausimas. Teigiama, kad vienos meninės tiesos koncepcijos orientuojasi į tradicinę, gnoseologinę tiesos, kaip minties atitikimo tikrovei, sampratą, o kitose koncepcijose menine tiesa laikoma formos ir išraiškos vienovė, kūrinio autentiškumas, turinio reikšmingumas, emocinis poveikis ir panašiai. Pirmosios, daugiausia materialistinei estetikai atstovaujančios, meninės tiesos koncepcijos tiesą mene traktuoja kaip teisingą reiškinių esmės atskleidimą per individualius charakterius, įvykius, tipiškų reiškinių bruožų perteikimą ir kita. Teigiama, kad meno kūriniams tiesiogiai negalima priskirti teiginių statuso, nes meninė išmonė tiesiogiai neturi loginio teiginio, pažintinio vaizdo prasmės. Nagrinėjant tiesą mene reikia atsižvelgti į savitą tikrovės atspindėjimo ir meninės išmonės santykį mene, aiškinti jo pažintinės funkcijos realizavimo būdą.

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13

Hollier, Denis. "While the City Sleeps: Mene, Mene, Tekel, Upharsin." October 64 (1993): 3. http://dx.doi.org/10.2307/778711.

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14

Schwarz, Daniel R. "“Mene, Mene, Tekel, Upharsin”: Jewish perspectives in Disraeli's fiction." Jewish History 10, no. 2 (September 1996): 37–55. http://dx.doi.org/10.1007/bf01650960.

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15

Shabes, Sore. "Mener Zogn/Men Say." Bridges: A Jewish Feminist Journal 12, no. 2 (October 2007): 44–49. http://dx.doi.org/10.2979/bri.2007.12.2.44.

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16

Fuxe, K. "Menek Goldstein (1926â1997)." Trends in Pharmacological Sciences 19, no. 1 (January 1, 1998): 1. http://dx.doi.org/10.1016/s0165-6147(97)01145-0.

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17

Marneffe, B. R. "Broken Promises, Mended Dreams." Journal of Studies on Alcohol 47, no. 1 (January 1986): 89–90. http://dx.doi.org/10.15288/jsa.1986.47.89.

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18

Mähönen, Jukka. "Minne menet, velkojiensuoja yhteisöoikeudessa?" Helsinki Law Review 14, no. 1 (February 8, 2021): 8–11. http://dx.doi.org/10.33344/vol14iss1pp8-11.

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19

Mulcahy, Joanne B. "Weave and Mend." Frontiers: A Journal of Women Studies 21, no. 3 (2000): 197. http://dx.doi.org/10.2307/3347120.

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20

Hancocks, Stephen. "On the mend." British Dental Journal 215, no. 6 (September 2013): 263. http://dx.doi.org/10.1038/sj.bdj.2013.882.

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21

Margetis, Martin. "‘PATCH-AND-MEND’." Journal of the American Dental Association 134, no. 9 (September 2003): 1167. http://dx.doi.org/10.14219/jada.archive.2003.0342.

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22

Vollans, Caroline. "On the MEND." Nursery World 2017, no. 14 (July 10, 2017): 16–17. http://dx.doi.org/10.12968/nuwa.2017.14.16.

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23

Charlotte, Schubert. "Mend the gap." Nature Medicine 9, no. 3 (March 2003): 267. http://dx.doi.org/10.1038/nm0303-267.

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24

Csukás, Adam. "Mene Tekel 2018." PRÁVNĚHISTORICKÉ STUDIE 2018, no. 1 (August 15, 2018): 161–62. http://dx.doi.org/10.14712/2464689x.2018.33.

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25

Martini, Eva, Susanne M. Krug, Britta Siegmund, Markus F. Neurath, and Christoph Becker. "Mend Your Fences." Cellular and Molecular Gastroenterology and Hepatology 4, no. 1 (July 2017): 33–46. http://dx.doi.org/10.1016/j.jcmgh.2017.03.007.

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26

Clay, Cathy. "On the Mend." Chest 151, no. 2 (February 2017): 509. http://dx.doi.org/10.1016/j.chest.2016.07.031.

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27

Oved, Kfir, Eran Eden, Chantal Van Houten, Tanya Gottlieb, Roy Navon, Asi Cohen, Olga Boico, et al. "A Novel Host-protein Assay Accurately Distinguishes Bacterial From Viral Upper Respiratory Tract Infections." Open Forum Infectious Diseases 4, suppl_1 (2017): S351—S352. http://dx.doi.org/10.1093/ofid/ofx163.847.

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Abstract Background Bacterial and viral infections are often clinically indistinguishable, particularly in upper respiratory tract infections (URTI), which leads to antibiotic misuse. A novel assay (ImmunoXpert™) that integrates measurements of three host-response proteins (TRAIL, IP-10, CRP) was recently developed to assist in differentiation between bacterial and viral etiologies. We evaluated the assay performance in URTI patients and compared it with standard laboratory measures. Methods We performed a sub-analysis of 464 patients with clinical suspicion of URTI enrolled in three previously conducted multi-center clinical studies that evaluated the assay performance in patients with acute infections: ‘Curiosity’ study (NCT01917461), ‘Opportunity’ study (NCT01931254), and ‘Pathfinder’ study (NCT01911143). Comparator method was predetermined criteria combined with expert panel adjudication, which was blinded to the test results. Diagnostic performance was evaluated by comparing test and comparator method outcomes. Results A unanimous panel adjudication was attained for 61 bacterial (13%) and 241 viral (52%) patients (162 patients (35%) had an indeterminate diagnosis). The assay distinguished between bacterial and viral infected patients with a sensitivity of 92% (95% CI: 82%- 98%) and specificity of 93% (88%-96%) with 11% equivocal test results. Overall the assay outperformed other routine laboratory tests (FIG 1), including: white blood cell count (WBC; cutoff 15,000 cells/µL, sensitivity 48% (35%-60%), P < 10-−6; specificity 85% (80%-90%), P < 0.05); CRP (cutoff 40 mg/L, sensitivity 82% (72%–92%), P = 0.16, specificity 79% (74%–84%), P < 10-4); Procalcitonin (PCT; cutoff 0.5 ng/mL, sensitivity 22% (11%–32%), P < 10–14, specificity 80% (74%–85%), P < 0.001); absolute neutrophil count (ANC; cutoff 10,000 cells/µL, sensitivity 58% (45%–71%), P < 10-−4, specificity 94% (91%–97%), P = 0.7). Conclusion The novel assay demonstrated superior performance compared with routine laboratory tests (WBC, ANC) and biomarkers (CRP, PCT), in distinguishing bacterial from viral etiologies in patients with URTI. It has the potential to help clinicians avoid missing bacterial infections or prescribing unwarranted antibiotics for viral URTIs. Disclosures K. Oved, MeMed Diagnostics: Board Member, Employee and Shareholder, Salary E. Eden, MeMed Diagnostics: Board Member, Employee and Shareholder, Salary T. Gottlieb, MeMed Diagnostics: Employee, Salary R. Navon, MeMed Diagnostics: Employee, Salary A. Cohen, MeMed Diagnostics: Employee, Salary O. Boico, MeMed Diagnostics: Employee, Salary M. Paz, MeMed Diagnostics: Employee, Salary L. Etshtein, MeMed Diagnostics: Employee, Salary G. Kronenfeld, MeMed Diagnostics: Employee, Salary T. Friedman, MeMed Diagnostics: Employee, Salary E. Bamberger, MeMed Diagnostics: Employee, Salary I. Chistyakov, MeMed Diagnostics: Consultant, Consulting fee I. Potasman, MeMed Diagnostics: Holding stock options, stock options

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28

Mastboim, Niv, Kfir Oved, Tanya Gottlieb, Asi Cohen, Roy Navon, Meital Paz, Ellen Bamberger, et al. "873. Using the Host Immune Response to Identify Viral-Bacterial Coinfection in Children With Respiratory Syncytial Virus Infection." Open Forum Infectious Diseases 5, suppl_1 (November 2018): S25—S26. http://dx.doi.org/10.1093/ofid/ofy209.057.

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Abstract Background A major challenge in the effective management of children with RSV infection is the clinical difficulty of distinguishing a simple viral from viral–bacterial coinfections. As a result, despite the low rates of viral–bacterial coinfection, RSV patients are often prescribed antibiotics with recent reports demonstrating more than 60% antibiotic overuse rates (Van Houten et al. 2018). Here, we examined whether a host-immune signature combining the viral-induced proteins TRAIL and IP-10 with the bacterial-induced protein CRP (ImmunoXpert; Oved et al. 2015) can distinguish simple viral from viral–bacterial coinfection in RSV patients. Methods We studied 402 febrile children enrolled as part of “Curiosity,” a prospective study designed to develop and validate the host-immune signature. Infection etiology—viral or viral-bacterial coinfection—was determined by a panel of experts following a review of patients’ clinical, laboratory, radiological, microbiological, and follow-up data. RSV strains were detected using a respiratory multiplex PCR applied to nasal swabs (Seeplex-RV15). Results Out of the 402 children with suspected acute infection 29 had a positive RSV detection (Figure 1); of them, 27 had a unanimous expert panel etiology determination: 24 viral and 3 viral–bacterial coinfections. Out of the 24 patients unanimously assigned viral by the expert panel, 13 were given antibiotics, indicating a 54% antibiotic overuse rate. The host-immune signature correctly identified all 3 viral-bacterial coinfection cases, as well as 22 out of the 24 (92%) simple viral patients. This finding supports that the signature has the potential to reduce antibiotic overuse by 6.5-fold (from an overuse of 13/24 = 54% to 2/24 = 8%, P < 0.001). Conclusion Our results demonstrate high antibiotic overuse rates for RSV patients, consistent with previous reports. The host-immune signature correctly distinguished simple viral from viral–bacterial coinfection and therefore may have the potential to aid physicians in the correct management of children with RSV infection. Implementation studies are required to evaluate its utility in safely decreasing unnecessary antibiotic use for RSV patients. Disclosures N. Mastboim, MeMed Diagnostics: Employee, Salary. K. Oved, MeMed Diagnostics: Board Member, Employee and Shareholder, Salary. T. Gottlieb, MeMed Diagnostics: Employee, Salary. A. Cohen, MeMed Diagnostics: Employee, Salary. R. Navon, MeMed Diagnostics: Employee, Salary. M. Paz, MeMed Diagnostics: Employee, Salary. E. Bamberger, MeMed Diagnostics: Employee, Salary. T. Friedman, MeMed Diagnostics: Employee, Salary. L. Etshtein, MeMed Diagnostics: Employee, Salary. O. Boico, MeMed Diagnostics: Employee, Salary. I. Potasman, MeMed Diagnostics: Holding stock options, Stock options. E. Eden, MeMed Diagnostics: Board Member, Employee and Shareholder, Salary. L. Shani, MeMed Diagnostics: Employee, Salary.

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29

Arens, Ilmar. "“Mene-Mene-Tekel-Ufarsin:” Öselian superintendent Oldekop against the Swedish government." Journal of Baltic Studies 24, no. 1 (March 1993): 3–8. http://dx.doi.org/10.1080/01629779200000211.

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30

Griffen, Tom. "Heresies by Orlando Ricardo Menes." Prairie Schooner 90, no. 2 (2016): 179–81. http://dx.doi.org/10.1353/psg.2016.0206.

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31

Heikkinen, Anja. "Hyvin menee, jos siltä näyttää." Aikuiskasvatus 29, no. 4 (December 15, 2009): 315–16. http://dx.doi.org/10.33336/aik.94218.

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32

Langslet,, Gisle, Inger Ottestad,, Kjetil Retterstøl,, and Leiv Ose. "Klinisk legemiddelutprøvning – hva mener deltakerne?" Tidsskrift for Den norske legeforening 130, no. 19 (2010): 1909. http://dx.doi.org/10.4045/tidsskr.09.0030.

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33

Hancocks, S. "Today the tap was mended." British Dental Journal 188, no. 8 (April 2000): 466. http://dx.doi.org/10.1038/sj.bdj.4800511.

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34

Hancocks, OBE, S. "Today the tap was mended." British Dental Journal 188, no. 08 (April 22, 2000): 466. http://dx.doi.org/10.1038/sj.bdj.4800511a.

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35

Lucas, D. "JEAN-FRANCOIS MENEZ( 1950-1996)." Alcohol and Alcoholism 31, no. 3 (May 1, 1996): 229–30. http://dx.doi.org/10.1093/oxfordjournals.alcalc.a008140.

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36

Olsen, Jan Abel. "Hva menes med «sykdommens alvorlighetsgrad»?" Tidsskrift for Den norske legeforening 133, no. 1 (2013): 64–67. http://dx.doi.org/10.4045/tidsskr.12.0659.

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37

Funk, Michael A. "Protein backbone, broken and mended." Science 359, no. 6377 (February 15, 2018): 756.12–758. http://dx.doi.org/10.1126/science.359.6377.756-l.

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38

Lipinski, Jerry, Arielle Thiel, Angelo Pagani, Michael Otto, Melinda Johnston, Zoheir Abdelbaki, Prabhakar Parsa, John Sirak, and Sandeep M. Patel. "Even Mended Hearts Can Break." JACC: Case Reports 1, no. 4 (December 2019): 487–92. http://dx.doi.org/10.1016/j.jaccas.2019.10.010.

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39

Große-Nobis, W. "Hans Horst Mende zum Gedenken." Physik Journal 43, no. 7 (July 1987): 268. http://dx.doi.org/10.1002/phbl.19870430728.

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40

Reguero Ugarte, Urtzi. "XVIII. mende erdialdeko Etxalarko dotrina." Fontes Linguae Vasconum, no. 124 (December 26, 2017): 355–67. http://dx.doi.org/10.35462/flv124.5.

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Artikulu honek XVIII. mendearen erdialdean Joan Bautista Sanzberro etxalartarrak idatzitako euskarazko dotrinaren edizio filologikoa dakar. Testuaren edizioarekin batera, hizkuntza-azterketa eta garai bertsuko beste testu batzuetako euskararekin egindako konparazioa ere badaude.

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41

Skotland, Sidsel. "Mener FHI ikke holder løftene." Rus & samfunn 9, no. 04 (October 20, 2016): 7–9. http://dx.doi.org/10.18261/issn1501-5580-2016-04-03.

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42

Ruud, Marit Ekne. "Hva menes med begrepet boligbehov?" Plan 47, no. 06 (January 4, 2016): 10–15. http://dx.doi.org/10.18261/issn1504-3045-2015-06-03.

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43

Lariccia, Vincenzo, Michael Fine, Simona Magi, Mei-Jung Lin, Alp Yaradanakul, Marc C. Llaguno, and Donald W. Hilgemann. "Massive calcium–activated endocytosis without involvement of classical endocytic proteins." Journal of General Physiology 137, no. 1 (December 27, 2010): 111–32. http://dx.doi.org/10.1085/jgp.201010468.

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We describe rapid massive endocytosis (MEND) of >50% of the plasmalemma in baby hamster kidney (BHK) and HEK293 cells in response to large Ca transients. Constitutively expressed Na/Ca exchangers (NCX1) are used to generate Ca transients, whereas capacitance recording and a membrane tracer dye, FM 4–64, are used to monitor endocytosis. With high cytoplasmic adenosine triphosphate (ATP; >5 mM), Ca influx causes exocytosis followed by MEND. Without ATP, Ca transients cause only exocytosis. MEND can then be initiated by pipette perfusion of ATP, and multiple results indicate that ATP acts via phosphatidylinositol-bis 4,5-phosphate (PIP2) synthesis: PIP2 substitutes for ATP to induce MEND. ATP-activated MEND is blocked by an inositol 5-phosphatase and by guanosine 5′-[γ-thio]triphosphate (GTPγS). Block by GTPγS is overcome by the phospholipase C inhibitor, U73122, and PIP2 induces MEND in the presence of GTPγS. MEND can occur in the absence of ATP and PIP2 when cytoplasmic free Ca is clamped to 10 µM or more by Ca-buffered solutions. ATP-independent MEND occurs within seconds during Ca transients when cytoplasmic solutions contain polyamines (e.g., spermidine) or the membrane is enriched in cholesterol. Although PIP2 and cholesterol can induce MEND minutes after Ca transients have subsided, polyamines must be present during Ca transients. MEND can reverse over minutes in an ATP-dependent fashion. It is blocked by brief β-methylcyclodextrin treatments, and tests for involvement of clathrin, dynamins, calcineurin, and actin cytoskeleton were negative. Therefore, we turned to the roles of lipids. Bacterial sphingomyelinases (SMases) cause similar MEND responses within seconds, suggesting that ceramide may be important. However, Ca-activated MEND is not blocked by reagents that inhibit SMases. MEND is abolished by the alkylating phospholipase A2 inhibitor, bromoenol lactone, whereas exocytosis remains robust, and Ca influx causes MEND in cardiac myocytes without preceding exocytosis. Thus, exocytosis is not prerequisite for MEND. From these results and two companion studies, we suggest that Ca promotes the formation of membrane domains that spontaneously vesiculate to the cytoplasmic side.

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Lev, Shaul, Tamar Gottesman, Gal Shachaf Levin, Tahel Ilan Ber, Alon Angel, Lior Kellerman, Eran Barash, et al. "426. Use of Real Time IP-10 Measurements to Identify and Monitor the Dysregulated Immune Response in COVID-19 Patients." Open Forum Infectious Diseases 7, Supplement_1 (October 1, 2020): S279—S280. http://dx.doi.org/10.1093/ofid/ofaa439.620.

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Abstract Background It is estimated that up to 10% of SARS-CoV-2 patients progress from early and pulmonary stages to the most severe stage of illness, which manifests as an extra-pulmonary systemic hyperinflammatory syndrome. Interferon gamma-induced protein 10 (IP-10) is an inflammatory marker that plays a role in the dysregulated host response of COVID-19 infected patients. Clinical monitoring of IP-10 has been restricted in the absence of a rapid diagnostic test. MeMed KeyTM is a novel platform recently cleared to provide IP-10 measurements in 15 minutes. We hypothesized that providing physicians with real time IP-10 measurements would support detection and continuous monitoring of patients with a dysregulated immune response and potentially allow personalized immunomodulation to improve patient outcome. IP-10 levels reflect corticosteroid treatment Methods From 7th April 2020 to 10th May 2020 blood was routinely collected serially from 52 SARS-CoV-2 positive patients hospitalized at a COVID-19 dedicated medical center. A clinical decision support protocol was in place focused on managing viral response, oxygenation and inflammatory state (NCT04389645). Results The median age of the 52 patients was 69, 69% were male, 21% were ventilated, 4 died, 2 due to non-COVID-19 related complications. The most common comorbidities were Diabetes 40% and Hypertension 46%. IP-10 >1000 pg/ml correlated with ICU admission (p< 0.05) and increased COVID-19 severity score (p< 0.01). 19 of the 52 patients had IP-10 >1000 pg/ml, of these 12 were treated with corticosteroids. Monitoring IP-10 within the clinical decision support protocol assisted with personalized corticosteroid regimens with the aim of reducing IP-10 < 1000 pg/ml. The 10 patients that survived exhibited IP-10 levels >1000 pg/ml for 2.6 days on average. In contrast, the 2 patients that died of COVID-19 related complications displayed an average of 7.5 days with IP-10 >1000 pg/ml (p< 0.05). Conclusion Providing physicians with real time measurements of IP-10 in COVID-19 patients proved a useful tool as part of the clinical decision support protocol. Timely identification, monitoring and personalized treatment of COVID-19 patients exhibiting a dysregulated immune response may aid in improving patient outcome. Further studies are warranted. Disclosures Tahel Ilan Ber, MD, MeMed (Employee) Alon Angel, n/a, MeMed (Employee) Lior Kellerman, M.D, MeMed (Employee) Eran Barash, MA, MeMed (Employee) Roy Navon, MSc, MeMed (Employee) Einav Simon, PhD, MeMed (Employee) Noa Avni, PhD, MeMed (Employee) Mary Hainrichson, PhD, MeMed (Employee) Tanya Gottlieb, PhD, MeMed (Employee) Kfir Oved, MD, PhD, MeMed (Employee) Eran Eden, PhD, MeMed (Employee)

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45

O’Sullivan, Gerry. "Derrida on the Mend." International Philosophical Quarterly 26, no. 1 (1986): 95–96. http://dx.doi.org/10.5840/ipq198626152.

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46

Naeem, Maryam. "Books: Mend the Living." British Journal of General Practice 67, no. 663 (September 29, 2017): 466. http://dx.doi.org/10.3399/bjgp17x692873.

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Fackelmann, Kathy A. "Myelin on the Mend." Science News 137, no. 14 (April 7, 1990): 218. http://dx.doi.org/10.2307/3974498.

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Inada, Kenneth K., and Robert Magliola. "Derrida on the Mend." Buddhist-Christian Studies 5 (1985): 218. http://dx.doi.org/10.2307/1390311.

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Koelb, Clayton, and Robert Magliola. "Derrida on the Mend." Comparative Literature 38, no. 4 (1986): 366. http://dx.doi.org/10.2307/1770398.

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50

MADDOCKS, IAN. "On the alternative mend." Medical Journal of Australia 147, no. 11-12 (December 1987): 620–21. http://dx.doi.org/10.5694/j.1326-5377.1987.tb133708.x.

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Journal articles on the topic 'Mened'

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