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1

Almon, Willy Kurnia, Muhammad Fidel Ganis Siregar, M. Rhiza Z. Tala, Makmur Sitepu, Ichwanul Adenin, and Muara Panusunan Lubis. "Effect of Soy Isoflavones Compared to Estradiol Valerate in Menopausal Women assessed by Menopause Quality of Life Questionnaire." Open Access Macedonian Journal of Medical Sciences 10, B (2022): 752–56. http://dx.doi.org/10.3889/oamjms.2022.8749.

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BACKGROUND: There has recently been a global effort to develop preparations that aim for benefits of hormone replacement therapy with minimal discomfort or risk while isoflavones administration found to relieve complaints related to menopause and has been widely carried out. AIM: The aim of the study is to determine the effect of soy isoflavone compared to estradiol valerate administration in postmenopausal women assessed by the Menopause Quality of Life (MENQOL) questionnaire. METHODS: This is an experimental study with pre-post test non-randomized design using data from postmenopausal women
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Smail, Linda, Ghufran Jassim, and Anam Shakil. "Menopause-Specific Quality of Life among Emirati Women." International Journal of Environmental Research and Public Health 17, no. 1 (2019): 40. http://dx.doi.org/10.3390/ijerph17010040.

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To investigate the quality of life (QOL) of menopausal Emirati women aged 40–64 years and determine its relationship with their sociodemographic characteristics. A community-based cross-sectional study was conducted on 70 Emirati women using multistage stratified clustered random sampling. The participants were interviewed face-to-face using a structured questionnaire comprising sociodemographic variables, reproductive characteristics, and the Menopause-Specific Quality of Life (MENQOL) questionnaire. The most common symptom among the study participants was ‘aching in the muscles’. The partici
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Siregar, Muhammad FG, Masakazu Terauchi, Jonathan T. Lumbantobing, et al. "Role of serum estradiol and C-telopeptide on musculoskeletal pain in menopausal women." Narra J 4, no. 2 (2024): e747. http://dx.doi.org/10.52225/narra.v4i2.747.

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Musculoskeletal pain is one of the common symptoms of menopause syndrome throughout the world. Estradiol is the most potent and abundant derivative of estrogen and is associated with musculoskeletal pain, stiffness, and depressed mood during the menopausal transition. C-telopeptide is a molecule released during osteoclastic bone resorption and degradation of type I collagen, which is reported to have higher levels in individuals with musculoskeletal pain. An observational analytical study with a cross-sectional design was used in this research. Estradiol and C-telopeptide levels were measured
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M. Kus Fitriani Fruitasari. "Yoga Meningkatkan Kualitas Hidup Wanita Menopause: Scoping Review Berbasis MENQOL." Jurnal Medika Nusantara 2, no. 2 (2024): 231–39. http://dx.doi.org/10.59680/medika.v2i2.1248.

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Background: Menopause have a significant impact on a woman's quality of life. Yoga has been proposed as a non-pharmacological intervention to improve the quality of life of postmenopausal women. This scoping review aims to identify and analyze existing literature regarding the effectiveness of yoga interventions on the quality of life of menopausal women as measured by the Menopause-Specific Quality of Life Questionnaire (MENQoL). Methods: A literature search was conducted on electronic databases including PubMed, Scopus, and Web of Science for studies published up to 2024. Inclusion criteria
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R.Hanitha Rajasekar and Sowmiya.KR. "Analysis of Subjective Well-being of Menopausal Women in a Rural Area of Tamil Nadu; Let Menopause be a period of Hope." Indian Journal of Public Health Research & Development 16, no. 3 (2025): 226–33. https://doi.org/10.37506/275sk879.

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Introduction: The Third National Revised Consensus Guidelines of the Indian Menopause Society have projected that by the year 2026, the menopausal population will be 103 million. Women should be well educated about this phase of life, and prior counseling should also be given to those in menopause transition. This study was done to assess the quality of life among menopausal women so that their menopause journey is a sustainable one. Materials and methods A cross-sectional study was conducted for one year in the Rural field practice area of Kanchipuram district among 300 post-menopausal women
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Maunsell, Elizabeth, Paul E. Goss, Rowan T. Chlebowski, et al. "Quality of Life in MAP.3 (Mammary Prevention 3): A Randomized, Placebo-Controlled Trial Evaluating Exemestane for Prevention of Breast Cancer." Journal of Clinical Oncology 32, no. 14 (2014): 1427–36. http://dx.doi.org/10.1200/jco.2013.51.2483.

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Purpose Exemestane, a steroidal aromatase inhibitor, reduced invasive breast cancer incidence by 65% among 4,560 postmenopausal women randomly assigned to exemestane (25 mg per day) compared with placebo in the National Cancer Institute of Canada (NCIC) Clinical Trials Group MAP.3 (Mammary Prevention 3) trial, but effects on quality of life (QOL) were not fully described. Patients and Methods Menopause-specific and health-related QOL were assessed by using the four Menopause-Specific Quality of Life Questionnaire (MENQOL) domains and the eight Medical Outcomes Study Short Form Health Survey (S
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Hwang, Ye-chae. "A Case Report of a Medial Medullary Infarction Patient with Menopausal Hot Flashes." Journal of Internal Korean Medicine 45, no. 1 (2024): 119–30. http://dx.doi.org/10.22246/jikm.2024.45.1.119.

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This case study reports on the effectiveness of Korean medicine treatment for menopausal hot flashes in stroke patients. During hospitalization, a female patient with medial medullary infarction was diagnosed with menopausal hot flashes and received treatment with traditional Korean medicine and acupuncture. The assessment was performed by monitoring daily habits to relieve hot flashes. The hot flash index, menopause rating scale (MRS), menopause-specific quality of life (MENQoL) questionnaire, and Kupperman index (KI) were also used. After 28 days of treatment, the hot flash index improved fr
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Lim, Eun Yeong, So-Young Lee, Hee Soon Shin, et al. "The Effect of Lactobacillus acidophilus YT1 (MENOLACTO) on Improving Menopausal Symptoms: A Randomized, Double-Blinded, Placebo-Controlled Clinical Trial." Journal of Clinical Medicine 9, no. 7 (2020): 2173. http://dx.doi.org/10.3390/jcm9072173.

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This study evaluated the efficacy of Lactobacillus acidophilus YT1 (MENOLACTO) for alleviating menopausal symptoms. This study was a multi-center, randomized, double-blinded, placebo-controlled clinical trial involving female subjects (ages: 40–60 years) with menopausal symptoms and a Kupperman index (KMI) score ≥ 20. Subjects were administered 1 × 108 CFU/day MENOLACTO or placebo, with the primary endpoint being total KMI score, and the effect of secondary endpoints on alleviating menopausal symptoms according to individual categories of the modified KMI, as well as a quality of life question
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Nissy, V. L., Gopika Gopinathan Bhaskaran, S. S. Lal, and G. K. Mini. "Menopause-Specific Quality of Life among Rural Women: A Community-based Cross-sectional Study in Kerala, India." Journal of Mid-life Health 16, no. 1 (2025): 67–75. https://doi.org/10.4103/jmh.jmh_171_24.

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ABSTRACT Aim and Objectives: The health of women in the menopausal age is often ignored by most healthcare programs in countries like India. The aim of this study is to estimate the prevalence and pattern of menopause-specific quality of life (MENQOL) and associated factors of rural women in Kerala, India. Materials and Methods: A cross-sectional community-based study was conducted among menopausal women in the Thiruvananthapuram district of Kerala using a multistage random sampling method. We collected details of basic sociodemographic and reproductive problems using a pretested semi-structur
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Rodrigo, Chithramali Hasanthika, Ruwan Ferdinando, and Rohini De Alwis Seneviratne. "Menopause specific quality of life and correlated factors among Sri Lankan post-menopausal women." Journal of the College of Community Physicians of Sri Lanka 30, no. 3 (2024): 170–79. http://dx.doi.org/10.4038/jccpsl.v30i3.8628.

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Introduction: During menopause declining ovarian function gives rise to menopausal symptoms. Menopause specific quality of life could be assessed based on the distress caused by menopausal symptoms.Objectives: To describe menopause specific quality of life and correlated factors among post-menopausal women aged 45-55 years in Kalutara district, Sri Lanka.Methods: A community based cross sectional study was conducted in Kalutara district among 756 post-menopausal women using multistage stratified cluster sampling. Women were interviewed by trained data collectors using a structured questionnair
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Yazdi, Zohreh, Khosro Sadeghniiat-Haghighi, Amir Ziaee, Khadijeh Elmizadeh, and Masomeh Ziaeeha. "Influence of Sleep Disturbances on Quality of Life of Iranian Menopausal Women." Psychiatry Journal 2013 (2013): 1–5. http://dx.doi.org/10.1155/2013/907068.

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Background. Subjective sleep disturbances increase during menopause. Some problems commonly encountered during menopause, such as hot flushes and sweating at night, can cause women to have difficulty in sleeping. These complaints can influence quality of life of menopausal women.Methods. This cross-sectional study was performed on menopausal women attending health centers in Qazvin for periodic assessments. We measured excessive daytime sleepiness by Epworth sleepiness scale (ESS), obstructive sleep apnea (OSA) by the Berlin questionnaire, and insomnia by the insomnia severity index (ISI). We
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Bień, Agnieszka, Magdalena Korżyńska-Piętas, Marta Zarajczyk, et al. "Factors Determining the Quality of Life of Polish Women during Menopause Based on the Menopause-Specific Quality of Life Questionnaire." Healthcare 11, no. 8 (2023): 1173. http://dx.doi.org/10.3390/healthcare11081173.

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Background: The aim of the study was to present the process of cultural adaptation to Polish conditions and the validation of a scale assessing the quality of life of Polish women during the menopause and to identify the factors determining this quality of life. Methods: The research tools were the menopause-specific quality of life (MENQOL) questionnaire and a standardized interview questionnaire comprising questions on the participants’ characteristics. The study involved 516 women using health care services who had symptoms caused by the menopause. Results: The value of the Cronbach’s alpha
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Meggetto, Olivia, Elizabeth Maunsell, Rowan Chlebowski, Paul Goss, Dongsheng Tu, and Harriet Richardson. "Factors Associated With Early Discontinuation of Study Treatment in the Mammary Prevention.3 Breast Cancer Chemoprevention Trial." Journal of Clinical Oncology 35, no. 6 (2017): 629–35. http://dx.doi.org/10.1200/jco.2016.68.8895.

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Purpose Aromatase inhibitors are established breast cancer chemoprevention interventions. However, nonadherence remains a significant challenge. We investigated the association between worsening menopause-specific quality of life, baseline participant characteristics, and early treatment discontinuation within the Mammary Prevention.3 (MAP.3) breast cancer prevention trial. Methods In the MAP.3 randomized, placebo-controlled trial evaluating exemestane, participants completed the Menopause-Specific Quality of Life Questionnaire (MENQOL) at entry and at 6 months. Multivariable log-binomial regr
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Ramugade, Divya, and Ashwini Shitre. "Open-Labeled, Randomized, Prospective Controlled Clinical Study to Assess Efficacy of Rasayana Churna and Pranayama in the Management of Rajonivritti Lakshanas w. s. r. to Postmenopausal Syndrome." International Journal of Ayurvedic Medicine 13, no. 4 (2023): 952–56. http://dx.doi.org/10.47552/ijam.v13i4.2964.

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Background: In modern science, hormonal replacement therapy (HRT) is the only alternative for postmenopausal syndrome whereas non-hormonal pharmacologic therapies have been shown to be less effective than hormonal therapy. So, it was assumed that Rasayana Churna along with Pranayama would be effective in relieving postmenopausal symptoms. Objective: to assess the clinical efficacy of Rasayana Churna and Pranayama in the management of Rajonivritti Lakshanas w. s. r. to Postmenopausal Syndrome. Methods: The present open-labeled, randomized, prospective controlled clinical study was conducted aft
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Sydora, Beate C., Hilary Fast, Sandy Campbell, Nese Yuksel, Jacqueline E. Lewis, and Sue Ross. "Use of the Menopause-Specific Quality of Life (MENQOL) questionnaire in research and clinical practice." Menopause 23, no. 9 (2016): 1038–51. http://dx.doi.org/10.1097/gme.0000000000000636.

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Gaikwad, Madhu, Shubhra Agrawal Gupta, Mini Sharma, Nirmal Verma, and Shweta Shalini. "A cross-sectional study to assess the prevalence of menopausal symptoms among middle aged female teachers in schools of Raipur city." International Journal Of Community Medicine And Public Health 7, no. 4 (2020): 1560. http://dx.doi.org/10.18203/2394-6040.ijcmph20201474.

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Background: Middle age is a bridge between adulthood and old age, which requires special attention. During middle age physical changes like menopause, aging along with psychological and social changes occur which may affect over all well-being and positive mental health status. So, the present study has been planned to assess the prevalence of menopausal symptoms among middle aged working females.Methods: The present study was cross-sectional study carried out in 40 schools of Raipur city from 2017 to 2019. By using systematic random sampling method 40 schools were selected and from each schoo
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Hisworo, Muhammad Ramadhan, Muhammad Fidel Ganis Siregar, Hotma Partogi Pasaribu, et al. "Selenium Levels based on Various Menopause Complaints Assessed by Menopause-specific Quality of Life Questionnaire before and after Selenium Intervention." Open Access Macedonian Journal of Medical Sciences 10, B (2022): 2470–75. http://dx.doi.org/10.3889/oamjms.2022.10955.

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BACKGROUND: Menopausal symptoms can greatly affect a woman’s personal, social, and work life. Selenium functions as a cofactor for glutathione peroxidase and helps minimize oxidative damage through cellular metabolism in postmenopausal women when estradiol production decreases, antioxidant protection is lost and therefore oxidative stress is increased. AIM: The aim of the study was to evaluated effect of selenium supplementation on selenium levels based on menopausal complaints assessed by menopause-specific quality of life questionnaire (MENQOL). MATERIALS AND METHODS: This research is an ana
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Balan, Andreea, Marius Alexandru Moga, Andrea Elena Neculau, et al. "Royal Jelly and Fermented Soy Extracts—A Holistic Approach to Menopausal Symptoms That Increase the Quality of Life in Pre- and Post-menopausal Women: An Observational Study." Nutrients 16, no. 5 (2024): 649. http://dx.doi.org/10.3390/nu16050649.

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Background: The objective of this study was to determine the effects of royal jelly and fermented soy extracts on menopausal symptoms and on quality of life in pre- and post-menopausal women. Materials and method: This prospective observational study was carried out in a Clinical Hospital of Brasov, Romania, during June 2020 and December 2021. Eighty pre- and post-menopausal women, aged between 45 and 60 years, were included in two groups. The first group (40 women) received a dietary supplement with fermented soy extract twice a day for eight weeks and the second group (40 women) received the
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Suthar, Himani, and Payal Gahlot. "Ab. No. 167 Association between Balance, Cognition and Quality of Life in Middle Aged Postmenopausal Women: A Cross Sectional Study." Journal of Society of Indian Physiotherapists 8, no. 1 (2024): 94. http://dx.doi.org/10.4103/jsip.jsip_abstract_97.

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Introduction: The hormonal changes occurring in women during and after menopause transition have a relevant impact on physical performance and health-related quality of life. The use of challenging balance conditions to detect sub clinical risk of balance impairment has been reported in aging population. Postmenopausal women may experience a decline in cognitive skills in their daily lives. A decrease in functional performance and cognitive function may lead to poor quality of life in postmenopausal women. There are studies reporting that low physical function can predict low cognitive functio
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Lewis, Jacqueline E., John R. Hilditch, and Cindy J. Wong. "Further psychometric property development of the Menopause-Specific Quality of Life questionnaire and development of a modified version, MENQOL-Intervention questionnaire." Maturitas 50, no. 3 (2005): 209–21. http://dx.doi.org/10.1016/j.maturitas.2004.06.015.

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Wahyuningsih, Adella, Tiyas Kusumaningrum, and Gadis Meinar Sari. "THE RELATIONSHIP OF DISTANCE TO HEALTH FACILITIES AND PHYSICAL ACTIVITIES IN RELATION TO THE QUALITY OF LIFE OF POSTMENOPAUSAL WOMEN." SEAJOM: The Southeast Asia Journal of Midwifery 7, no. 1 (2021): 22–27. http://dx.doi.org/10.36749/seajom.v7i1.102.

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Quality of menopaused women’s life is influenced by several factors such as age, education level, occupation, and physical activity. Quality of life has concepts such as physical well-being, functional ability, and emotional or social well-being which ultimately lead to changes in individuals. Objective: to analyze factors related to the quality of postmenopausal women’s life. Methods: This observational analytic study used a cross sectional design. The population was all postmenopausal women who filled out online questionnaires using google forms distributed through social media with a sampli
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Imperatrice, Maria, Anissa Lasfar, Colin A. J. van Kalkeren, and Freddy Troost. "Olive Leaf Extract Supplementation Improves Postmenopausal Symptoms: A Randomized, Double-Blind, Placebo-Controlled Parallel Study on Postmenopausal Women." Nutrients 16, no. 22 (2024): 3879. http://dx.doi.org/10.3390/nu16223879.

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Menopause negatively impacts women’s health. Objectives: The aim of this study was to investigate whether an olive leaf extract (OLE) improves postmenopausal symptoms, body composition, handgrip strength and blood lipid profile in postmenopausal women. In a randomized, double-blinded parallel study design, 60 healthy postmenopausal women aged 47–70 years received either OLE (250 mg/day) or placebo supplementation for 12 weeks. Postmenopausal symptoms were assessed with the Menopause-Specific Quality of Life Questionnaire (MENQoL), the Hot Flash Interference scale (HFI), and body composition an
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Choi, Seo Yeon, Purum Kang, Hui Su Lee, and Geun Hee Seol. "Effects of Inhalation of Essential Oil ofCitrus aurantiumL. var.amaraon Menopausal Symptoms, Stress, and Estrogen in Postmenopausal Women: A Randomized Controlled Trial." Evidence-Based Complementary and Alternative Medicine 2014 (2014): 1–7. http://dx.doi.org/10.1155/2014/796518.

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This study aimed to investigate the effects of inhalation of the essential oil ofCitrus aurantiumL. var.amara(neroli oil) on menopausal symptoms, stress, and estrogen in postmenopausal women. Sixty-three healthy postmenopausal women were randomized to inhale 0.1% or 0.5% neroli oil or almond oil (control) for 5 minutes twice daily for 5 days. Menopause-related symptoms, as determined by the Menopause-Specific Quality of Life Questionnaire (MENQOL); sexual desire visual analog scale (VAS); serum cortisol and estrogen concentrations, blood pressure, pulse, and stress VAS, were measured before an
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Koirala, Dipti, Nirupa Thapa, and Sarala Shrestha. "Quality of life of postmenopausal women of Kaski district." Nepal Journal of Obstetrics and Gynaecology 15, no. 1 (2020): 43–49. http://dx.doi.org/10.3126/njog.v15i1.29340.

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Aim: To assess menopause specific quality of life of postmenopausal women.
 Method: This descriptive survey was carried out among postmenopausal women aged 40 to 60 years residing in a municipality of Kaski district of Nepal. Data was collected from 150 women meeting the criteria through face to face interview using a structured questionnaire consisting of socio-demographic items and Menopause-Specific Quality of Life (MENQOL) scale.
 Results: Respondents’ mean age and SD was 52.83±4.19 years and their mean menopausal age and SD was 47.12±4.34 years. The most common menopausal sympto
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Gürler, Meryem, Aynur Kızılırmak, and Mürüvvet Baser. "The Effect of Aromatherapy on Sleep and Quality of Life in Menopausal Women with Sleeping Problems: A Non-Randomized, Placebo-Controlled Trial." Complementary Medicine Research 27, no. 6 (2020): 421–30. http://dx.doi.org/10.1159/000507751.

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<b><i>Introduction:</i></b> Menopause is the termination of menstruation and fertility. Women commonly experience sleeping problems during the menopausal period. Aromatherapy is among the complementary therapies used to remedy sleeping problems. <b><i>Methods:</i></b>This study aims to investigate the effects of lavender oil on sleep and quality of life of menopausal women through steam inhalation. This study was quasi-experimental with pre-test/post-test placebo control groups. It was conducted with 57 women, 27 of whom were subject to aromather
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Brennan, Donal J., Fatima Cardoso, Paula Briggs, et al. "Impact of elinzanetant on sleep disturbances and quality of life in women undergoing adjuvant endocrine therapy for breast cancer: Phase 3 OASIS 4 trial." Journal of Clinical Oncology 43, no. 16_suppl (2025): 12063. https://doi.org/10.1200/jco.2025.43.16_suppl.12063.

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12063 Background: Vasomotor symptoms (VMS) and sleep disturbances are common in women taking adjuvant endocrine therapy (AET) for hormone receptor-positive (HR+) breast cancer and can impact quality of life and treatment adherence, potentially affecting breast cancer outcomes. There are few efficacious treatments and none approved in this indication. Elinzanetant (EZN) is a dual neurokinin-1 and -3 receptor antagonist in development for the treatment of VMS. Methods: OASIS 4 (NCT05587296) is a 52-week randomized, placebo-controlled phase 3 trial evaluating the safety and efficacy of EZN for th
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Palaz, Serap, and Onur Yavaş. "MENOPAUSE IN THE WORKPLACE: PRELIMINARY FINDINGS AMONG FEMALE HEALTHCARE PROFESSIONALS IN TÜRKİYE." Yönetim ve Ekonomi Araştırmaları Dergisi 23, no. 2 (2025): 196–209. https://doi.org/10.11611/yead.1683946.

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The aim of this study was to examine the prevalence of menopausal symptoms among healthcare professionals and to assess their impact on work performance and career decisions. This descriptive cross-sectional study targeted female healthcare professionals working in both the public and private sectors. Menopausal symptoms were assessed using the Menopause-Specific Quality of Life Questionnaire (MENQOL). Additionally, a participant information form was used to investigate symptom variation across demographic variables, and a workplace menopause questionnaire was used to assess the impact of thes
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Dharmarajlu, Santhi M. "Effect of lifestyle modification education on knowledge, attitude, and quality of life on menopause among middle-aged teachers." African Journal of Reproductive Health 28, no. 11 (2024): 170–80. https://doi.org/10.29063/ajrh2024/v28i11.17.

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All women go through menopause at some point in their lives, but because of the nature of their jobs, teachers have it harder than other female employees. This study aimed to assess middle-aged teachers' knowledge, attitudes, and quality of life-related to menopause after receiving education on health-promoting lifestyle modification. A quasi-experimental Time Series design with pre-intervention, immediate, post-intervention, and a three-month follow-up was employed in this study. Through a purposive sampling technique, 84 middle-aged teachers were selected. A pre-designed questionnaire was us
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Singh, Pragya, Shaili Vyas, Vidisha Vallabh, Ruchira Nautiyal, Abhay Srivastava, and Jayanti Semwal. "A Study to Assess the Prevalence and Factors Affecting Menopausal Symptoms among Middle-Aged Females in the Garhwal Region of Uttarakhand." Journal of Mid-life Health 14, no. 4 (2023): 237–45. http://dx.doi.org/10.4103/jmh.jmh_198_22.

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ABSTRACT Background: Middle age is a link between adulthood and old age, which requires special attention. During middle age among females, changes like menopause occur, which is responsible for causing various physical, vasomotor, psychological, and social changes, which may affect overall well-being and positive mental health status. Hence, the present study has been planned to assess the prevalence of menopausal symptoms among middle-aged females. Materials and Methods: The present study was a cross-sectional study carried out in rural and urban areas of district Dehradun among 400 females.
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Gul, Naima. "Identifying Perimenopausal Symptoms in Women Diagnosed With Depression: A Focused Audit at a Tertiary Care Hospital." BJPsych Open 10, S1 (2024): S234. http://dx.doi.org/10.1192/bjo.2024.572.

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AimsThis audit aimed to assess the recognition and management of perimenopausal symptoms in women diagnosed with depression at the Psychiatry Outpatient Department (OPD) of Benazir Bhutto Hospital, Pakistan. It focused on identifying gaps in screening for perimenopausal symptoms among these patients.MethodsConducted over a year, this retrospective audit included 250 women aged 45–55 years, previously diagnosed with depression. Post-diagnosis screening for perimenopausal symptoms was performed using the Menopause-Specific Quality of Life Questionnaire (MENQOL) and the Greene Climacteric Scale.
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Whelan, Timothy J., Paul E. Goss, James N. Ingle, et al. "Assessment of Quality of Life in MA.17: A Randomized, Placebo-Controlled Trial of Letrozole After 5 Years of Tamoxifen in Postmenopausal Women." Journal of Clinical Oncology 23, no. 28 (2005): 6931–40. http://dx.doi.org/10.1200/jco.2005.11.181.

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Purpose To evaluate the impact of letrozole compared with placebo after adjuvant tamoxifen on quality of life (QOL) in the MA.17 trial. Methods Patients completed the Short Form 36-item Health Survey (SF-36) and the Menopause Specific Quality of Life Questionnaire (MENQOL) at baseline, 6 months, and annually. Mean change scores from baseline were compared between groups for summary measures and domains. A response analysis compared the proportion of patients who demonstrated an important change in QOL. Results Of 5,187 randomly assigned women in the trial, 3,612 (69.9%) participated in the QOL
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Nardina, Evita Aurilia, Ratih Kumala Dewi, and Etni Dwi Astuti. "MENGURAI TANTANGAN MENOPAUSE PREKOKS: DAMPAKNYA TERHADAP KUALITAS HIDUP WANITA." Jurnal Ilmu Keperawatan dan Kebidanan 16, no. 1 (2025): 33–44. https://doi.org/10.26751/jikk.v16i1.2668.

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Premature menopause, occurring before the age of 40, can significantly impact women’s quality of life, encompassing physical, psychological, social, and environmental aspects. This study aims to identify factors associated with the quality of life of women experiencing premature menopause at Krobokan Public Health Center. The research design is cross-sectional, involving 98 respondents selected through purposive sampling. Quality of life was measured using the Menopause Specific Quality of Life Questionnaire (MENQOL). Chi-square test results showed significant associations between age (p-value
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Shirazi, Mahboobeh, Mohamad Naser Jalalian, Masoumeh Abed, and Marjan Ghaemi. "The Effectiveness of Melissa Officinalis L. versus Citalopram on Quality of Life of Menopausal Women with Sleep Disorder: A Randomized Double-Blind Clinical Trial." Revista Brasileira de Ginecologia e Obstetrícia / RBGO Gynecology and Obstetrics 43, no. 02 (2021): 126–30. http://dx.doi.org/10.1055/s-0040-1721857.

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Abstract Objective The present study aimed to assess the effect of Melissa Officinalis L. (a combination of lemon balm with fennel fruit extract) compared with citalopram and placebo on the quality of life of postmenopausal women with sleep disturbance. Methods The present study is a randomized, double-blind, placebo clinical trial among 60 postmenopausal women with sleep disturbance who were referred to a university hospital from 2017 to 2019. The participants were randomized to receive M. Officinalis L. (500 mg daily), citalopram (30 mg) or placebo once daily for 8 weeks. The Menopause-Speci
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Bhattarai, Kritika, Srijat Dahal, Mamta, and Manish Subedi. "Quality of Life Among Post-Menopausal Women Residing in Selected Ward of Itahari Sub-Metropolitan City, Nepal." European Journal of Theoretical and Applied Sciences 1, no. 4 (2023): 944–56. http://dx.doi.org/10.59324/ejtas.2023.1(4).89.

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Background: Menopause is a critical period in a woman’s life that not only marks the end of reproductive ability but is also associated with multiple vasomotor, psychological, physical and sexual complaints. So, the study of Quality of Life in the post-menopause has become an essential component in clinical practices. The objective of this research was to assess the quality of life among post-menopausal women. Materials and Methods: A descriptive cross-sectional study was conducted among 102 women of Itahari Sub- Metropolitan city. Probability sampling technique was used to select the ward and
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Kritika, Bhattarai, Dahal Srijat, K.c Mamta, and Subedi Manish. "Quality of Life Among Post-Menopausal Women Residing in Selected Ward of Itahari Sub-Metropolitan City, Nepal." European Jornal of Theoretical and Sciences 1, no. 4 (2023): 944–56. https://doi.org/10.59324/ejtas.2023.1(4).89.

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Background: Menopause is a critical period in a woman’s life that not only marks the end of reproductive ability but is also associated with multiple vasomotor, psychological, physical and sexual complaints. So, the study of Quality of Life in the post-menopause has become an essential component in clinical practices. The objective of this research was to assess the quality of life among postmenopausal women. Materials and Methods: A descriptive crosssectional study was conducted among 102 women of Itahari Sub- Metropolitan city. Probability sampling technique was used to select the ward
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36

Park, Kang-In, Yeon-Kyoung Pak, Kyoung-Sun Park, et al. "A Study on the Relationship between Body Composition and Menopause Rating Scale (MRS), The Menopause-specific Quality of Life Questionnaire (MENQOL) of Postmenopausal Women." Journal of Oriental Obstetrics and Gynecology 28, no. 1 (2015): 85–91. http://dx.doi.org/10.15204/jkobgy.2015.28.1.085.

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Moskalewicz, Alexandra, Amy Di Tomaso, Jacob J. Kachura, et al. "Gynecologic Symptoms among Hormone Receptor-Positive Breast Cancer Patients on Oral Endocrine Therapy: A Cross-Sectional Study." Current Oncology 29, no. 3 (2022): 1813–27. http://dx.doi.org/10.3390/curroncol29030149.

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Endocrine therapy (ET) for hormone receptor-positive (HR+) breast cancer can contribute to gynecologic symptoms (GS) that impact vaginal health, sexual function, and quality of life (QoL). A cross-sectional study was conducted at St. Michael’s Hospital in Toronto, Canada between July 2017 and June 2018 to examine the occurrence and frequency of GS among HR+ breast cancer patients on ET, patient-provider communication, female sexual dysfunction (FSD), and QoL. A Treatment Experience questionnaire was developed for this study and the Female Sexual Function Index (FSFI) and Menopause-Specific Qua
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Langley, Paul C. "Post-Menopausal Quality of Life Claims: Overlooking the Requirements of Normal Science and Fundamental Measurement in ICER’S Cost-Effectiveness Assessment of Fezolinetant for Moderate to Severe Vasomotor Symptoms." INNOVATIONS in pharmacy 14, no. 1 (2023): 9. http://dx.doi.org/10.24926/iip.v14i1.5118.

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One of the signal failures in health technology assessment is the absence of consideration given, not only to the standards of normal science, but to those of fundamental measurement. A recent evidence report by the Institute for Clinical and Economic Review (ICER) is emblematic of this failure. Based on a simple linear regression model that translates aggregate scores from the ordinal Menopause-specific Quality of Life Questionnaire (MENQOL) to the ordinal EuroQol EQ-5D-5L, ICER has applied these scores to an assumption driven model simulation to produce preferences, QALYs and incremental cos
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Nita, Rada, I. Anand Nalini, Punatar Priti, and Barkhede Mohini. "A Hospital-Based Study on Menopausal Symptoms and Quality of Life among Postmenopausal Women." International Journal of Pharmaceutical and Clinical Research 16, no. 4 (2024): 692–96. https://doi.org/10.5281/zenodo.11178755.

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<strong>Introduction:</strong>&nbsp;Menopause represents a significant physiological event in a woman&rsquo;s life, marking the cessation of reproductive capability. The transition is often accompanied by a range of physical and physiological symptoms, which can profoundly impact a woman&rsquo;s quality of life (QOL). Studies suggest that more than 80% of women experience various menopause-related symptoms, influencing their overall health and well-being. Study aims to evaluate menopause-related symptoms&rsquo; prevalence and impact on quality of life among postmenopausal women, with objective
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Bushmakin, AG, S. Tatlock, N. Williamson, et al. "Development and Evaluation of a Crosswalk between the Eq-5d-5l And Menopause-Specific Quality of Life (Menqol) Questionnaire in Postmenopausal Women." Value in Health 19, no. 3 (2016): A178. http://dx.doi.org/10.1016/j.jval.2016.03.1412.

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Naqvi, Waqar M. "A COMMUNITY SURVEY ON EFFECT OF STEP AEROBIC EXERCISES AND MUSIC THERAPY ON MENTAL HEALTH IN MENOPAUSAL WOMEN." Journal of Medical pharmaceutical and allied sciences 10, no. 4 (2021): 3300–3303. http://dx.doi.org/10.22270/jmpas.v10i4.1306.

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To evaluate the effect of Step aerobic exercises and music therapy on mental health in menopausal women. Menopausal women of selected areas of Belagavi city were screened in a door to door survey using Menopause Quality Of Life (MENQOL) questionnaire. 69 menopausal women who fulfilled the inclusion criteria were divided randomly into 3 groups Group A was administrated Music therapy, for Group B Step Aerobic Exercises was given and Group C was administrated combination of Music therapy and step aerobic exercises. All three groups showed significant changes from pre and post intervention. The p-
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Farooque, SM, Raveena Basumatary, and Prasanta Kumar Das. "Examining the Quality of Life among Working Women in Agartala During the Menopausal Transition: An In-Depth Analysis." American Journal of Physical Education and Health Science 2, no. 2 (2024): 10–16. http://dx.doi.org/10.54536/ajpehs.v2i2.2983.

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Menopause is a critical phase in a woman’s life characterized by hormonal changes that can impact various aspects of health, including the quality of life. Despite the increasing number of women in the workforce, there is a noticeable gap in specific challenges and experiences of working women during the menopausal transition. The study aims to analyze the quality of life among working women in Agartala during the menopausal transition. The study includes N=30 working women from diverse professional backgrounds in Agartala. Data were collected through the MENQOL (Menopause-Specific Quality of
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Natalia Lugovaia. "Efficacy of Body-Oriented Psychotherapy in Alleviating Climacteric Symptoms and Menopause Manifestations." Journal of Information Systems Engineering and Management 10, no. 34s (2025): 389–95. https://doi.org/10.52783/jisem.v10i34s.5814.

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The climacteric symptoms experienced by menopausal women significantly affect their quality of life. These changes can lead to sexual dysfunction, an increased risk of osteoporosis, cardiovascular disease, cancer, psychiatric disorders, and chronic kidney disease. The psychological impact of menopausal symptoms is also high, including mood swings, depression and anxiety. In our study, we evaluated the effectiveness of body-oriented psychotherapy in alleviating menopausal symptoms in women aged 45 years and older. Twelve women with menopausal symptoms were interviewed in a structured survey bas
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Aikaterini E. Sousamli and Panagiota D. Dourou. "Association between menopause and quality of life: A cross-sectional study using data from women living in Northern Greece." World Journal of Advanced Research and Reviews 25, no. 3 (2025): 1377–88. https://doi.org/10.30574/wjarr.2025.25.3.0839.

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Menopause represents a significant life transition for women. Given the prolongation in women’s life expectancy, they will spend a large period of their lives in the postmenopausal stage. The lack of female hormones causes physical and psychological symptoms that negatively affect quality of life. Common vasomotor symptoms include hot flashes, night sweats, sleep disturbances, sexual dysfunction, and weight gain, while psychological symptoms involve anxiety, depression, and irritability. This study aimed to evaluate menopausal symptoms and their effect on women’s quality of life. The study sam
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Mohanta, Munu, Malvika Dwivedi, Mahul Mukherjee, and Sunetra Kaviraj Roy. "A community-based study on menopausal symptoms and quality of life in postmenopausal women in a rural area of West Bengal." International Journal Of Community Medicine And Public Health 12, no. 6 (2025): 2753–60. https://doi.org/10.18203/2394-6040.ijcmph20251723.

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Background: Menopausal health demands priority in Indian scenario due to increase in life expectancy and growing population of menopausal women. There is considerably lack of awareness about the effects of the menopausal symptoms in women in India. This study was done to find out the sociodemographic and behavioural characteristics of the study population, to assess Quality of Life (QOL) of the study population by Menopause-Specific Quality of Life Questionnaire (MENQOL) and to elicit the association between menopausal symptoms and sociodemographic and behavioural characteristics of the respon
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Premji, Sarah K., Vera J. Suman, Lida A. Mina, et al. "Abstract P2-03-07: Neoadjuvant (Z)-endoxifen for Premenopausal Estrogen Receptor (ER)+, Human Epidermal Growth Factor Receptor 2 (HER2)- Breast Cancer (BC): Evaluation of Quality of Life (QOL) measures in the EVANGELINE Study." Clinical Cancer Research 31, no. 12_Supplement (2025): P2–03–07—P2–03–07. https://doi.org/10.1158/1557-3265.sabcs24-p2-03-07.

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Abstract Background: Premenopausal women (PrW) with ER+, HER2- breast cancer (BC) are commonly treated with aromatase inhibitors (AI) with ovarian function suppression (OFS) or tamoxifen (tam) +/- OFS. Common adverse effects (AE) include musculoskeletal symptoms, hot flashes, night sweats, mood changes, and sexual side effects that may seriously impact quality of life (QOL). In SOFT, compared to tam alone, pts treated with tam + OFS had more hot flashes, loss of sexual interest, sleep disturbances, and vaginal dryness. In the combined SOFT/TEXT analysis, pts receiving exemestane + OFS had grea
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Radzinsky, Viktor E., Mekan R. Orazov, Marina B. Khamoshina, Roman E. Orekhov, and Irina S. Zhuravleva. "Efficacy and safety of non-hormonal agents for vasomotor symptoms of menopause: A prospective, double-blind, placebo-controlled study." Gynecology 25, no. 2 (2023): 144–52. http://dx.doi.org/10.26442/20795696.2023.2.202215.

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Aim. To assess the safety and efficacy of non-hormonal agents for mild vasomotor symptoms of menopause.&#x0D; Materials and methods. The study included 173 females aged 4855 with mild vasomotor symptoms during the early postmenopausal period. Patients in the study cohort were stratified into two groups by the double-blind method. In group 1 (study), the patients took the homeopathic agent Neoclimsal 1 tablet 4 times a day sublingually until completely dissolved for 4 weeks (n=86). In group 2 (n=87), the patient received a placebo (30 mg of microcrystalline cellulose) in a regimen mimicking the
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48

Akhila, M., and Laxmipriya Dei. "A Crosssectional survey research to assess the determinants of Menopause, prevalence and severity of menopausal symptoms and its impact on quality of life of menopausal women." Journal of Ayurvedic and Herbal Medicine 9, no. 1 (2023): 1–6. http://dx.doi.org/10.31254/jahm.2023.9101.

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Background: Menopause is usually associated with inevitable manifestation of ageing process in women. In Ayurveda Rajonivrutti is described as end of Artava Pravrutti. This is associated with distressing physical, pshycological, vasomotor and sexual symptoms that degrades the quality of life- and life-threatening health risks. Aims and objectives: Aim was to create awareness regarding predisposing factors, preventive and treatment measures among menopausal women. Objective was to find out the prevalence, severity of menopausal symptoms and quality of life, to assess the role of sociodemographi
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Noll, J., A. Metse, P. Gardiner, L. Pernoud, J. Scott, and M. Schaumberg. "P081 Sleep health in community-dwelling midlife women and associations with menopausal symptoms: a cross-sectional study." Sleep Advances 5, Supplement_1 (2024): A57. https://doi.org/10.1093/sleepadvances/zpae070.163.

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Abstract Introduction Sleep health or, ‘healthy sleep’, is a multidimensional construct, more than the absence of a sleep disorder. Menopausal women often experience sleep disturbances, yet the impact of menopausal symptoms on the likelihood of poorer sleep health remains unclear. This study examined how domains of menopausal symptoms (vasomotor, psychosocial, physical and sexual) relate to sleep health in Australian middle-aged women. Methods A total of 150 healthy women, aged 40-64 years, participated in this cross-sectional study. Sleep health was measured using the Ru-SATED questionnaire (
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50

Aikaterini E Sousamli and Panagiota D Dourou. "The impact of menopause on sexual health a cross-sectional study using data from women living in Northern Greece." World Journal of Advanced Research and Reviews 26, no. 3 (2025): 526–37. https://doi.org/10.30574/wjarr.2025.26.3.2176.

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Menopause represents a significant life transition for women, often accompanied by physical, psychological, and sexual health challenges. With the increasing life expectancy in women, a considerable part of their life will be spent in the postmenopausal period. The decline in estrogen levels leads to vasomotor symptoms, such as hot flashes and night sweats, as well as psychological symptoms, including anxiety, depression, and irritability. Sexual dysfunction is another key concern, with many menopausal women experiencing reduced libido, vaginal dryness, and pain during intercourse. This study
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