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Journal articles on the topic 'Mentzer Index'

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Published: 5 June 2025

Last updated: 16 July 2025

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1

Adiguna, Rhama, Doni Setiawan, Undang Ruhimat, and Rahayu Nirmatul Mutmainah. "Erythrocyte Index and Mentzer Index in Fathers of Thalassemia Patients." Mukhtabar : Journal of Medical Laboratory Technology 1, no. 1 (2023): 26–33. http://dx.doi.org/10.52221/mjmlt.v1i1.219.

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Background & Objective Thalassemia is a blood disorder caused by genetic factors that cause the globin chain in hemoglobin to not function normally. It is the most common hereditary disease in the world and in Ciamis Regency in 2021 there were 191 patients. Thalassemia prevention is carried out by screening to identify thalassemia carriers. Hematological examination in the form of erythrocyte index (MCV, MCH, MCHC) and mentzer index has been known to determine thalassemia screening. The purpose of this study was to determine the description of erythrocyte index and mentzer index in thalass

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2

Santika, I. Kadek Jaya. "Reliability Test of Different Red Blood Cell Discrimination Indices for Screening Iron Deficiency Anemia and Beta Trait Thalassemia in Pediatric Patients 6-59 Months of Age at Gema Santi Hospital, Nusa Penida, June 2023 - May 2024." International Journal of Health Sciences and Research 15, no. 2 (2025): 49–54. https://doi.org/10.52403/ijhsr.20250206.

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Introduction: Screening for iron deficiency anemia and thalassemia beta trait in hypochromic microcytic anemia in health facilities that do not have a complete examination is quite difficult. This study aims to determine the reliability of various indices against the Green and King index including the Mentzer index which is most used for screening. The results of the study can be used to determine whether the currently used indices are reliable enough to be used for patient screening. Material and Methods: This study used a cross-sectional method with a sample of patients aged 6-59 months who

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3

Auruba Manshah, Alia Halim, and Qurat-ul-ain. "Mentzer Index As Ascreening Toot For Iron Deficiency Anemia In 6 To 12 Years Old Children." Journal of Bacha Khan Medical College 5, no. 02 (2025): 166–71. https://doi.org/10.69830/jbkmc.v5i02.177.

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Objectives: to determine the diagnostic accuracy of mentzer index as a screening tool for iron deficiency anemia in 6 to 12 years old children taking serum ferritin as gold standard. Study Design: A Cross Sectional Study. Place And Duration Of Study: Department of Pediatrics PAF Hospital Islamabad from 22-Aug-2024 to 22-Dec 2024 Methodology: A cross sectional descriptive study was done on 150 children, 6-12 years of age, who were clinically suspected to have anemia. Blood examination including complete blood count was done for each patient and Mentzer index was determined. The children with in

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4

Aslam, Farhan, Savida Ilyas Dar, Sara Azam Shah, Muhammad Aqeel, Abdur Rehman, and Lubna Meraj. "Accuracy of Mentzer index for predicting iron deficiency anemia in adults." International Journal of Pathology 22, no. 3 (2024): 149–55. http://dx.doi.org/10.59736/ijp.22.03.916.

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Background: It is of great clinical significance to differentiate between causes of microcytic, hypo chromatic anemias, iron deficiency anemia being one of them as it will improve with iron supplements. Complete blood picture is unable to differentiate. Iron studies and Hemoglobin electrophoresis are expensive tests. This necessitates the need of a cost-effective test and therefore we tried to determine the effectiveness of mentzer index in predicting iron deficiency anemia. Methods: It was an Observational, Cross-sectional study, conducted in Department of General Medicine, Federal government

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Idrees, Muhammad, Jibran Umar Ayub Khan, Huma Riaz, Munawar Ali Shah, Hamidullah Shah, and Syed Mohammad Haris. "Utilization of Mentzer Index to Discriminate Between Beta Thalassemia Minor and Anemia of Iron Deficiency, Followed by HPLC." Pakistan Journal of Medical and Health Sciences 17, no. 1 (2023): 843–45. http://dx.doi.org/10.53350/pjmhs2023171843.

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Objective: Aim was to evaluate the sensitivity and specificity of Mentzer index in differentiating beta thalassemia minor from anemia of Iron deficiency. Materials and Methods: A cross-sectional study conducted in Hematology unit of Hayatabad Medical Complex .Sampling was done non-consecutively. A total of 860 cases with value of Hemoglobin less than 11 Gm/DL were counted. In all the selected cases full blood count were checked and Mentzer Index mean corpuscular volume [MCV] per RBCs count )was calculated. Value of <13 suggests the diagnosis of β Thalassemia minor/trait while more than 13 v

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Sonica, Rukwal, and Kaur Harpreet. "EVALUATION OF THE DIAGNOSTIC IMPORTANCE OF MENTZER INDEX FOR SCREENING THALASSEMIA MINOR AND DIFFERENTIATING IT FROM IRON DEFICIENCY." International Journal of Medical Laboratory Research 08, no. 02 (2023): 35–42. http://dx.doi.org/10.35503/ijmlr.2023.8205.

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Background and Aim: Mentzer index can differentiate microcytosis due to Thalassemia from other causes in a minimal resource setting and therefore, it can be playing a significant role in screening of Thalassemia in general population as well as distinguishing β Thalassemia trait from iron deficiency anemia has important clinical implications. The misdiagnosis of β Thalassemia trait has consequences for potential homozygous offspring leading to β Thalassemia disease. We aim to evaluate the diagnostic importance of Mentzer Index for screening Thalassemia minor as compared to other indices and di

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7

Kaur, Sukhmanjit, Sangeeta Pahwa, Simran Kakkar, and Japji Kaur. "Evaluation of efficacy of mentzer index for screening of beta - Thalassemia trait in antenatal women." Indian Journal of Obstetrics and Gynecology Research 11, no. 4 (2024): 591–94. http://dx.doi.org/10.18231/j.ijogr.2024.106.

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People with thalassemia trait should be distinguished from those who have anemia due to iron deficiency since they typically have mild microcytic hypochromic anemia and are mostly asymptomatic. : To evaluate efficacy of Mentzer index for screening Beta- Thalassemia trait in pregnant women.From January 2023 to October 2023, the observational study was carried out in the Department of Gynecology & Obstetrics at Sri Guru Ram Das Charitable Hospital Amritsar. The study comprised 130 pregnant women with anemia. To assess microcytic hypochromic anemia, tests like complete blood count (CBC), peri

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8

Amer, Johnny. "A Retrospective Study Using Mentzer Index for Prevalence of Iron Deficiency Anemia among Infants Visiting Maternal Centers at the Age of One Year." Anemia 2022 (March 27, 2022): 1–5. http://dx.doi.org/10.1155/2022/7236317.

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Anemia, defined as a hemoglobin level two standard deviations below the mean for age, is prevalent in infants and children worldwide. Characterizing anemia as microcytic and normocytic depends on the mean corpuscular volume (MCV), which is an important parameter in differentiating many types of anemia. Microcytic anemia due to iron deficiency is the most common type of anemia in children. In this study, we aimed to assess the Mentzer index used by the Ministry of Health (MOH) in Palestine as a useful tool in differentiating between iron deficiency anemia (IDA) and thalassemia. We assessed for

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9

Alam, Sri Lestari S., Rini Purnamasari, Erial Bahar, and Kemas Ya'kub Rahadian. "Mentzer index as a screening tool for iron deficiency anemia in 6-12-year-old children." Paediatrica Indonesiana 54, no. 5 (2014): 294. http://dx.doi.org/10.14238/pi54.5.2014.294-8.

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Background There is a high prevalence of iron deficiency anemia (IDA) in Indonesia. Iron deficiency anemia impairs the growth and development process in children. The reference standard to diagnose IDA is serum ferritin level. Since this test is expensive and rare not widely available, an inexpensive, simpler testis needed. The Mentzer index (mean corpuscular volume/red blood cell or MCV JRBC) has been used to identitY hypochromic-microcytic anemia with good validity.Objective To assess the validity of the Mentzer index for diagnosing IDA by comparing Mentzer indexes to serum ferritin and to d

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Obeagu, Emmanuel Ifeanyi. "Using Mentzer Index to Improve Anemia Management in Pregnancy: A Narrative Review." Asian Journal of Dental and Health Sciences 5, no. 1 (2025): 1–4. https://doi.org/10.22270/ajdhs.v5i1.106.

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Anemia during pregnancy is a significant public health challenge, affecting maternal well-being and fetal development. Among the most common causes are iron deficiency anemia (IDA) and thalassemia trait (TT), conditions requiring distinct management strategies. Accurate differentiation between these conditions is critical, as misdiagnosis can lead to suboptimal treatment outcomes. The Mentzer Index, calculated by dividing the mean corpuscular volume (MCV) by the red blood cell (RBC) count, offers a simple and reliable tool for distinguishing between IDA and TT, especially in resource-limited s

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11

Obeagu, Emmanuel Ifeanyi. "The Mentzer Index and Pregnancy: Differentiating Between Iron Deficiency and Thalassemia." Asian Journal of Dental and Health Sciences 5, no. 1 (2025): 5–10. https://doi.org/10.22270/ajdhs.v5i1.107.

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Anemia during pregnancy is a common condition with significant risks for both maternal and fetal health. The two primary causes of anemia in pregnancy—iron deficiency anemia (IDA) and thalassemia trait (TT)—require distinct treatment strategies. The Mentzer Index, a simple and cost-effective diagnostic tool, helps differentiate between these two types of anemia by calculating the ratio of mean corpuscular volume (MCV) to red blood cell (RBC) count. This review explores the role of the Mentzer Index in improving anemia diagnosis and management in pregnancy, highlighting its benefits and limitat

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12

Fridayenti, Fridayenti, Nadjwa Zamalek Dalimoenthe, Delita Prihatni, and Nina Susana Dewi. "Uji Validitas Panel Pemeriksaan Mean Corpuscular Volume, Indeks Mentzer dan Fragilitas Osmotik Tabung Tunggal untuk Skrining Talasemia Minor terhadap Pemeriksaan HbA2 Menggunakan High Performance Liquid Chromatography." Jurnal Ilmu Kedokteran (Journal of Medical Science) 16, no. 2 (2022): 89. http://dx.doi.org/10.26891/jik.v16i2.2022.89-98.

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Thalassemia is a disease caused by reduced or loss of synthesis of globin chains and then hemoglobin becomes abnormal. Characteristic screening in the population needs to be done to prevent marriage among people with thalassemia minor and reduce the birth of babies with thalassemia mayor. Combining several simple tests such as MCV, Mentzer index and single tube osmotic fragility test can increase the effectiveness of the test for screening of thalassemia minor. The purpose of this study was to determine the sensitivity and specificity of each panel for MCV-Mentzer index, MCV-single tube osmoti

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Obeagu, Emmanuel Ifeanyi. "Mentzer Index in High-Risk Pregnancies: Anemia Screening and Management." Asian Journal of Dental and Health Sciences 5, no. 1 (2025): 15–19. https://doi.org/10.22270/ajdhs.v5i1.113.

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Anemia remains a common and critical health issue in high-risk pregnancies, leading to adverse outcomes for both the mother and fetus, including preterm birth, low birth weight, and maternal fatigue. Differentiating between the two most common causes of microcytic anemia—iron deficiency anemia (IDA) and thalassemia trait (TT)—is essential for appropriate management. The Mentzer Index, calculated by dividing the mean corpuscular volume (MCV) by the red blood cell (RBC) count, has been proposed as a simple and effective tool to distinguish between these two conditions. This review explores the r

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Obeagu, Emmanuel Ifeanyi. "Assessing Anemia in Pregnant Women: The Usefulness of the Mentzer Index." Asian Journal of Dental and Health Sciences 5, no. 1 (2025): 20–24. https://doi.org/10.22270/ajdhs.v5i1.114.

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Anemia during pregnancy is a prevalent concern, with iron deficiency anemia (IDA) and thalassemia trait (TT) being two common causes. Differentiating between these conditions is crucial for effective management, as IDA requires iron supplementation, while TT does not. The Mentzer Index (MI) is a simple, cost-effective tool used to distinguish between IDA and TT by analyzing the mean corpuscular volume (MCV) and red blood cell (RBC) count. This review explores the usefulness of the Mentzer Index in assessing anemia in pregnant women, its clinical applications, benefits, and limitations in pract

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15

Oltean, Andreea, and Ioana Mihaela Chincesan. "MENTZER INDEX IN PEDIATRIC THALASSEMIA TRAIT." Jurnalul Pediatrului XXIII, no. 89-90 (2020): 35–40. http://dx.doi.org/10.37224/jp.2020.8990.07.

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16

Meshram, Pravin M., Hemant R. Kokandakar та Rajan S. Bindu. "Study of blood indices and high performance liquid chromatography (HPLC) in differentiation of β-thalassemia trait and iron deficiency anaemia". International Journal of Research in Medical Sciences 5, № 11 (2017): 4728. http://dx.doi.org/10.18203/2320-6012.ijrms20174666.

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Background: Iron deficiency anemia (IDA) and beta thalassaemia trait (BTT) are two of the most common causes of microcytic anemia.It is essential to differentiate between the two, so as to avoid unnecessary iron therapy which is contraindicated in beta thalassaemia .We retrospectively evaluated the reliability of various indices for differential diagnosis of microcytosis and 𝛽-TT in the same patient groups .Methods: A total of 200 patients were evaluated. We calculated 6 discrimination indices in all patients with anemia or suspected beta thalassemia. None of the subjects had combined IDA and

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17

Imrul Kayes, ASM Fazlul Haque, ASM Akramul Islam, and Chandan Kumar Shaha. "Comparison of the Diagnostic Value of Mentzer Index and RDW Index in the Screening of Beta Thalassemia Trait and Iron Deficiency Anemia." KYAMC Journal 15, no. 2 (2025): 73–76. https://doi.org/10.3329/kyamcj.v15i02.79628.

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Background: Beta thalassemia trait is one of the common forms of hemoglobinopathies in Bangladesh. Individuals having beta-thalassemia trait have microcytic hypochromic anemia and asymptomatic course may be similar as that of iron deficiency anemia (IDA).So, it is important to differentiate between beta- thalassemia trait and non-thalassemia microcytosis as both conditions share common characteristics. Though the definitive diagnosis those patients of thalassemia trait is possible only by Hb-electrophoresis their certain blood indices which can differentiate between thalassemia trait and iron

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18

Jaweria Bibi, Saima Bibi, Bibi Tayyaba Swati, Aleena Anees, and Alvina Butt. "Mentzer Index as a Screening Tool for Detecting Iron Deficiency Anemia Keeping Serum Ferritin as Gold Standard." Indus Journal of Bioscience Research 3, no. 6 (2025): 362–66. https://doi.org/10.70749/ijbr.v3i6.1658.

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Background: Iron-deficiency anemia remains a prevalent condition in children, with considerable effect on their development and growth. Early and accurate diagnosis is essential to effective management, particularly in a setting of low resources. The Mentzer index has been proposed to be a good screening tool for IDA based on its low cost and simplicity of performance, although its diagnostic accuracy regarding serum ferritin levels must be established. Objective: To determine the diagnostic accuracy of Mentzer index in detecting iron deficiency anemia taking serum ferritin as gold standard in

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Obeagu, Emmanuel Ifeanyi, and Getrude Uzoma Obeagu. "Screening for Thalassemia Traits in Pregnancy: The Role of Mentzer Index." International Journal of Medical Sciences and Pharma Research 10, no. 4 (2024): 50–55. https://doi.org/10.22270/ijmspr.v10i4.123.

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Thalassemia traits present significant challenges during pregnancy, often leading to complications such as anemia and adverse maternal and fetal outcomes. Early identification of carriers is essential for managing these risks and providing appropriate care. This review article examines the Mentzer Index, a straightforward and cost-effective tool derived from complete blood count (CBC) parameters, which can effectively screen for thalassemia traits in pregnant women. By calculating the ratio of mean corpuscular volume (MCV) to red blood cell (RBC) count, the Mentzer Index serves as a valuable f

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Ransom, Jacob, Aboko Princess, Evelyn Eze, and Jeremiah Zaccheaus. "Differential diagnosis of iron deficiency anemia and beta thalassemia in Port Harcourt pregnant women using the Mentzer Index." Sanamed 19, no. 2 (2024): 191–96. http://dx.doi.org/10.5937/sanamed0-51359.

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Introduction: The Mentzer index is a cost-effective and accurate method for differentiating between iron deficiency anemia (IDA) and beta-thalassemia. Anemia in pregnancy is a global health concern, especially in developing countries like Nigeria, where it is primarily linked to iron deficiency and may also include other underlying hemoglobin disorders, with beta-thalassemia (bT) being the most common. This cross-sectional study aimed to differentiate between iron deficiency anemia and beta-thalassemia in pregnant women attending tertiary hospitals in Port Harcourt, Nigeria, based on the Mentz

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Rastogi, Naincy, and Arvind S. Bhake. "Sehgal index and its comparison with Mentzer's index and Green and King index in assessment of peripheral blood smear with marked anisopoikilocytosis." International Journal of Research in Medical Sciences 8, no. 8 (2020): 2972. http://dx.doi.org/10.18203/2320-6012.ijrms20203449.

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Background: Mild microcytic hypochromic anaemias due to iron deficiency (IDA) and beta thalassemia trait(β-TT) continue to be a cause of significant burden to the society, particularly in the poorer developing countries. The objective of the present study was to study the RBC based indices in patients of marked anisopoikilocytosis in determining the etiology of it, to standardize few automated red cell parameters, and also objective grading of RBC morphology on peripheral smear and interpreting its utility in indicating a diagnosis. Also, to establish a relation between value of RBC indices wi

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Prameswari, Larasita, Linda Silvana Sari, and Ima Arum Lestarini. "Prevalence Of Suspected Beta Thalassemia Minor Based On Screening With Mentzer Index And Red Distribtion Width In Students Of Smp Negeri 7 Pujut." Unram Medical Journal 9, no. 2 (2020): 124–35. http://dx.doi.org/10.29303/jku.v9i2.417.

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Background : Beta thalassemia is blood disorder that it often found in Indonesia with high frequency of beta thalassemia carrier genes around 3 to 10%. Thalassemia has not been cured, but can be prevented by screening of thalassemia to identify individuals with beta minor thalassemia in population. The purpose of this study was to determine prevalence of anemia and prevalence of suspected beta thalassemia minor in students of SMP Negeri 7 Pujut based on Mentzer index and Red Distribution Width index. Methode: This study was an quantitative descriptive design with cross sectional approach

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Obeagu, Emmanuel Ifeanyi, and Getrude Uzoma Obeagu. "Insights into Maternal Health: Mentzer Index for Early Anemia Detection." International Journal of Medical Sciences and Pharma Research 10, no. 4 (2024): 44–49. https://doi.org/10.22270/ijmspr.v10i4.122.

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The Mentzer Index is a widely used hematological tool for differentiating between iron deficiency anemia and thalassemia, especially in resource-limited settings where advanced diagnostic options may be unavailable. Calculated as the ratio of mean corpuscular volume (MCV) to red blood cell (RBC) count, it provides a quick and accessible method for anemia screening. For values over 13, iron deficiency anemia is more likely, while values below 13 typically indicate thalassemia. This simplicity makes the Mentzer Index advantageous in primary healthcare and community health settings, supporting ea

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Rabbani, Sahar, Muhammad Farooq, Samina Naeem, Nasir Uddin, Muhammad Abdul Naeem, and Shahneela Jabeen. "DIAGNOSTIC EFFICACY OF RED BLOOD CELL INDICES IN DIAGNOSIS OF BETA THALASSEMIA TRAIT TAKING HAEMOGLOBIN ELECTROPHORESIS AS GOLD STANDARD." PAFMJ 71, no. 3 (2021): 1006–10. http://dx.doi.org/10.51253/pafmj.v71i3.3905.

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Objective: To determine the diagnostic efficacy of haematological indices for the diagnosis of beta thalassemia trait taking haemoglobin electrophoresis as a gold standard. Study Design: Cross sectional study. Place and Duration of Study: Department of Haematology Combined Military Hospital Lahore, from Aug to Dec 2019. Methodology: Two hundred and six anaemic patients 20-70 years of age of both genders were included in the study. Blood was collected from all the patients and complete blood count were generated through automated haematology analyser Sysmex KX-21. Based on the

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Shah, Tej Prakash, Anjan Shrestha, Jagdish Prasad Agrawal, Suman Rimal, and Anita Basnet. "Role of Mentzer Index for Differential Diagnosis of Iron Deficiency Anaemia and Beta Thalassemia Trait." Journal of Nepal Health Research Council 21, no. 1 (2023): 99–102. http://dx.doi.org/10.33314/jnhrc.v21i1.4479.

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Background: The most common differential diagnoses of microcytic hypochromic anaemia are iron deficiency anaemia and beta thalassemia. Globally, thalassemia affects approximately 4.4 out of every 10,000 live births whereas iron deficiency anaemia comprises half of all anaemia worldwide as per world health organization. The definitive diagnosis of beta thalassemia trait and iron deficiency anaemia requires haemoglobin analysis and iron studies respectively, which are not possible to perform in all suspected cases especially in resource limited settings. The study aims to evaluate the reliabilit

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Obeagu, Emmanuel Ifeanyi. "The Mentzer Index in Maternal Anemia: An Early Diagnostic Marker." Asian Journal of Dental and Health Sciences 5, no. 1 (2025): 25–29. https://doi.org/10.22270/ajdhs.v5i1.115.

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Maternal anemia is a prevalent condition that poses significant health risks to both mothers and their infants. Accurate and timely diagnosis is crucial for effective management, particularly in differentiating between iron deficiency anemia (IDA) and thalassemia trait (TT), two common causes of microcytic anemia during pregnancy. The Mentzer Index (MI), a simple and cost-effective diagnostic tool, is used to distinguish between these two conditions by calculating the ratio of mean corpuscular volume (MCV) to red blood cell (RBC) count. This review explores the utility of the Mentzer Index in

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Bhattacharya, Shreya, Surbhi Sinha, Kaur Tejinderjit Chahal, Md Ansar Akhtar, and Mala Mukherjee. "Role of Mentzer Index in Diagnostic Dilemma of Thalassemia Trait Viz A Viz Iron Deficiency Anaemia in A Teaching Hospital." International Journal of Pharmaceutical and Clinical Research 16, no. 1 (2024): 659–64. https://doi.org/10.5281/zenodo.11099535.

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<strong>Background</strong><strong>:</strong> Iron deficiency anaemia being the most common cause of anaemia in the world. The individuals suffering from thalassemia trait usually have an asymptomatic course and they present with mild microcytic hypochromic anaemia on peripheral blood smear. Since the other cause of microcytic anaemia is iron deficiency which is much more common therefore it is important to differentiate it from thalassemia trait. <strong>Objective:</strong> To determine the role of Mentzer index and Electrophoresis in differentiating between iron deficiency ana

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Obeagu, Emmanuel Ifeanyi. "Differential Diagnosis of Anemia in Pregnancy Using Mentzer Index: A Narrative Review." Asian Journal of Dental and Health Sciences 5, no. 1 (2025): 34–39. https://doi.org/10.22270/ajdhs.v5i1.117.

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Anemia in pregnancy remains a significant global health concern, contributing to adverse maternal and fetal outcomes. Among its most common etiologies are iron-deficiency anemia (IDA) and thalassemia traits, both requiring distinct management strategies. The Mentzer Index, calculated as the ratio of Mean Corpuscular Volume (MCV) to Red Blood Cell (RBC) count, has emerged as a practical, cost-effective tool for differentiating between these conditions. This simple calculation leverages routine complete blood count (CBC) parameters, offering a quick and accessible approach to initial anemia diag

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Arora, Sheetal, Deepshikha Rana, Sachin Kolte, Leelawathi Dawson, and Indrani Dhawan. "Validation of new indices for differentiation between iron deficiency anemia and beta thalessemia trait, a study in pregnant females." International Journal of Scientific Reports 4, no. 2 (2018): 26. http://dx.doi.org/10.18203/issn.2454-2156.intjscirep20180394.

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<p class="abstract"><strong>Background:</strong> The two most frequent types of microcytic hypochromic anemia in developing countries are beta thalassemia trait (𝛽-TT) and iron deficiency anemia (IDA). Several indices using blood cell count parameters have been suggested to differentiate between two. In this study we evaluated the reliability of three indices.</p><p class="abstract"><strong>Methods:</strong> The present cross-sectional study was carried out in 300 pregnant females in third trimester. Out of these, 90 microcytic hypochromic females were

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Obeagu, Emmanuel Ifeanyi. "Mentzer Index as an Indicator of Hematological Health in Pregnant Populations: A Review." Asian Journal of Dental and Health Sciences 5, no. 1 (2025): 30–33. https://doi.org/10.22270/ajdhs.v5i1.116.

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Hematological health in pregnancy is crucial for ensuring favorable maternal and fetal outcomes, as pregnancy often predisposes women to conditions like anemia. The Mentzer Index, a diagnostic ratio derived from routine complete blood count (CBC) parameters, has proven valuable in distinguishing between iron-deficiency anemia (IDA) and thalassemia traits, two prevalent yet distinct causes of anemia in pregnant populations. This tool's simplicity and cost-effectiveness make it especially useful in resource-limited settings, offering a practical approach to early diagnosis and tailored managemen

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Sherali, Atika, Abdul Ahad, Shiyam Sunder Tikmani, and Suman Sohail. "Screening of Iron Deficiency Anemia in Children Using Mentzer Index in Pakistan: A Cross Sectional Study." Global Pediatric Health 10 (January 2023): 2333794X2211309. http://dx.doi.org/10.1177/2333794x221130986.

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The objective of the study was to determine the diagnostic accuracy of Mentzer Index in children with hypochromic microcytic anemia by taking serum ferritin levels as a gold standard. This cross-sectional study was conducted in the Department of Pediatric Medicine, Liaquat National Hospital Karachi, from 1st January to 30th June 2022. Children age 1 to 5 years and both genders were included in this study. Children who have had a history of blood transfusion in the past 3 months or Thalassemia or blood disorders, chronic liver disease or kidney diseases, and children with malignancy and congeni

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Vehapoglu, Aysel, Gamze Ozgurhan, Ayşegul Dogan Demir, et al. "Hematological Indices for Differential Diagnosis of Beta Thalassemia Trait and Iron Deficiency Anemia." Anemia 2014 (2014): 1–7. http://dx.doi.org/10.1155/2014/576738.

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Background. The two most frequent types of microcytic anemia are beta thalassemia trait (β-TT) and iron deficiency anemia (IDA). We retrospectively evaluated the reliability of various indices for differential diagnosis of microcytosis andβ-TT in the same patient groups.Methods. A total of 290 carefully selected children aged 1.1–16 years were evaluated. We calculated 12 discrimination indices in all patients with hemoglobin (Hb) values of 8.7–11.4 g/dL. None of the subjects had a combined case of IDA andβ-TT. All children with IDA received oral iron for 16 weeks, and HbA2 screening was perfor

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Siswandari, W., L. Rujito, V. Indriani, and W. Djatmiko. "Mentzer Index Diagnostic Value in Predicting Thalassemia Diagnosis." IOP Conference Series: Earth and Environmental Science 255 (May 10, 2019): 012004. http://dx.doi.org/10.1088/1755-1315/255/1/012004.

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Obeagu, Emmanuel Ifeanyi. "Diagnostic Challenges in Maternal Anemia: Mentzer Index in Clinical Practice." Asian Journal of Dental and Health Sciences 5, no. 1 (2025): 11–14. https://doi.org/10.22270/ajdhs.v5i1.108.

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Maternal anemia is a significant health concern during pregnancy, as it poses risks for both maternal and fetal well-being. Two common causes of microcytic anemia in pregnant women are iron deficiency anemia (IDA) and thalassemia trait (TT). Distinguishing between these conditions is crucial, as their management differs substantially. The Mentzer Index (MI), a simple diagnostic tool, is commonly used to differentiate between IDA and TT based on the mean corpuscular volume (MCV) and red blood cell (RBC) count. However, while the MI is widely used due to its simplicity and cost-effectiveness, it

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Obeagu, Emmanuel Ifeanyi. "Clinical Utility of Mentzer Index in Pregnancy Anemia Screening Programs: A Narrative Review." Asian Journal of Dental and Health Sciences 5, no. 1 (2025): 40–44. https://doi.org/10.22270/ajdhs.v5i1.118.

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Anemia in pregnancy is a prevalent condition that can lead to severe complications for both mothers and their fetuses. Differentiating between the causes of anemia, particularly iron deficiency anemia (IDA) and thalassemia traits, is crucial for appropriate treatment. The Mentzer Index (MI) is a simple, cost-effective tool used to distinguish between these two common causes of microcytic anemia by comparing the mean corpuscular volume (MCV) to the red blood cell (RBC) count. This review explores the clinical utility of the MI in pregnancy anemia screening programs, highlighting its advantages,

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Gopchade, Dr Ajeet. "Mentzer Index for Differential Diagnosis of Iron Deficiency anaemia and Beta Thalassemia Trait." Journal of Medical Science And clinical Research 04, no. 12 (2017): 15138–42. http://dx.doi.org/10.18535/jmscr/v4i12.135.

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Obeagu, Emmanuel Ifeanyi, and Getrude Uzoma Obeagu. "Anemia in Pregnancy: Mentzer Index as a Predictor for Iron Supplementation Needs." International Journal of Medical Sciences and Pharma Research 10, no. 4 (2024): 39–43. https://doi.org/10.22270/ijmspr.v10i4.121.

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Anemia during pregnancy is a significant public health concern that affects a substantial proportion of women globally, with iron deficiency anemia being the most prevalent form. Effective early diagnosis and intervention are crucial to prevent adverse outcomes for both mothers and infants. The Mentzer Index, a simple calculation derived from the mean corpuscular volume (MCV) and red blood cell (RBC) count, serves as a useful tool to differentiate between iron deficiency anemia and thalassemia, thereby guiding appropriate treatment strategies. By categorizing the type of anemia, healthcare pro

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Monica, Molli, Sanapala Sridevi, Sirisha Gunta, et al. "Application of Various RBC Indices to Differentiate Iron Deficiency Anemia and Beta Thalassemia Trait Among Antenatal Women in A Tertiary Care Hospital." International Journal of Pharmaceutical and Clinical Research 15, no. 6 (2023): 149–56. https://doi.org/10.5281/zenodo.12113991.

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<strong>Introduction: </strong>The most frequent causes of microcytic anemia among antenatal women in India are iron deficiency anemia (IDA) and beta thalassemia trait(βTT). Hence it is important to differentiate between both the conditions to avoid unnecessary iron therapy in βTT patients. This study was done to screen antenatal women with β thalassemia trait using formulas derived from various Red cell indices. <strong>Aims And Objectives:</strong> This study aims to screen all microcytic (MCV<80fl) hypochromic (MCH<27pg) anemia for β thalassemia trai

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Dr, Ambhore Kuldip. "A Case of Thalassemia Trait Misdiagnosed as Iron Deficiency Anemia." International Journal Of Medical Case Reports 4, no. 2 (2023): 5–7. https://doi.org/10.5281/zenodo.12789380.

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Thalassemia trait is a common inherited disorder characterized by microcytic, hypochromic anemia, often misdiagnosed as iron deficiency anemia (IDA). This report describes a 3-year-old boy with persistent anemia unresponsive to oral iron therapy. Initial laboratory findings suggested IDA, but further investigation using the Mentzer index (MCV/RBC) indicated thalassemia trait. The diagnosis was confirmed by hemoglobin electrophoresis showing elevated Hb A2 levels. Discontinuation of iron supplementation and initiation of folic acid therapy led to clinical improvement. This case underscores the

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Ferdian, Budi Andri, Nelly Rosdiana, and Bidasari Lubis. "Impact of iron therapy on Mentzer index and red cell distribution width index in primary school children with iron deficiency anemia." Paediatrica Indonesiana 49, no. 4 (2009): 195. http://dx.doi.org/10.14238/pi49.4.2009.195-9.

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Background Iron deficiency anemia (IDA) remains a commonnutritional problem, especially in school-age children. Due tothe many examinations that are needed to be performed and the invasive gold standard procedure, an easy and simple alternative examination to diagnose IDA is needed.Objective To determine the impact of iron therapy on Mentzerand red cell distribution width (RDW) indexes of children withIDA.Methods A randomized open clinical trial was conducted inprimary school aged children in North Aek Nabara, betweenNovember 2006 and November 2007. IDA was determined basedon WHO criteria. Sub

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Ahmad, Sufia, Noorin Zaidi, Syed Riaz Mehdi, Sumaiya Irfan, and Sharique Ahmad. "Indices in differentiating iron deficiency anemia from thalassemia trait- a comparative study." Asian Journal of Medical Sciences 12, no. 10 (2021): 81–86. http://dx.doi.org/10.3126/ajms.v12i10.38268.

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Background: Iron deficiency anemia (IDA) and beta thalassemia trait (BTT) are the two most common and important causes of microcytic hypochromic anemia in India. It is very difficult to differentiate between the two. Many different types of techniques have been proposed for the same. While some are invasive like bone marrow examination others are not available at all centers, like electrophoresis. Hence different indices come into play. Aims and Objective: This study was undertaken to compare the efficacy of Shine and Lal index and Mentzer index in differentiating between IDA and BTT. Material

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Khan, Muhammad Ihtesham, Hamid Nawaz Khan, and Muhammad Usman. "BETA THALASSEMIA TRAIT." Professional Medical Journal 25, no. 04 (2018): 545–50. http://dx.doi.org/10.29309/tpmj/2018.25.04.343.

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Objectives: To assess the sensitivity of the various discrimination indicesas screening test in beta-thalassemia trait patients in our population. Study design: Crosssectional descriptive study. Period: 1-Sep 2012 to 31-Jan 2013 (5 months). Settings: PathologyDepartment, District Head Quarters (DHQ) Hospital, Rawalpindi. Materials and Methods: Atotal of 150 diagnosed cases of beta thalassemia trait were included in the study. Study wasdone from 1-Sep 2012 to 31-Jan 2013 in DHQ hospital, Rawalpindi. Four discrimination indicesi.e. Mentzer, Shine & Lal, Srivastava, and Red cell Distribution

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Munir, Asma, Arrosa Rahim, Faryal Zafar, Hafiz Muhammad Haseeb та Rabia Zahid. "Diagnostic Potential of Haematological Indices (Mentzer Index and RDWI) to Distinguish Iron Deficiency Anemia and βTT". Journal of Fatima Jinnah Medical University 18, № 02 (2024): 78–81. https://doi.org/10.37018/jfjmu/7881.

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ABSTRACTBackground: Iron Deficiency Anemia (IDA) and β-thalassemia trait (βTT) are the most frequently encountered entities presenting with microcytic hypochromic anemia. It is essential to distinguish between IDA and βTT to avoid incorrect diagnosis of βTT and unnecessary iron therapy. The high cost and inaccessibility of specific confirmatory tests has led to the utilization of different red blood cell (RBC) indices to differentiate them. The objective of this study was to assess the diagnostic accuracy of RDWI and Mentzer Index for screening and differentiation of IDA and βTT in terms of co

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Patil, Parag, Govindrao Kusneniwar, Gunvanti Rathod, et al. "A study to assess the occurrence of anaemia and beta-thalassemia in the tribal population residing in the Yadadri-Bhuvanagiri district of Telangana state." Journal of Family Medicine and Primary Care 13, no. 10 (2024): 4611–15. http://dx.doi.org/10.4103/jfmpc.jfmpc_553_24.

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ABSTRACT Background: This study aimed to estimate the prevalence of anaemia and haemoglobinopathies, particularly beta-thalassemia in the tribal population of the Yadadri-Bhuvanagiri district of Telangana. Methods: The sample consisted of a tribal population (Banjara) that visited voluntary blood camps set up in tribal settlements, local schools, and the Gram-panchayat office, in collaboration with local healthcare workers. Haemoglobin measurements (Anaemia) and Mentzer index of whole blood (EDTA) samples were used as diagnostic screening tools for categorising the population at risk of beta-t

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IQBAL, S., W. AMIN, S. ARSHAD, and NU AIN. "DIAGNOSTIC ACCURACY OF MENTZER INDEX AS A SCREENING TOOL FOR THE DIAGNOSIS OF IRON DEFICIENCY ANEMIA BY TAKING IRON PROFILE AS GOLD STANDARD IN PATIENTS PRESENTING WITH HYPOCHROMIC MICROCYTIC ANEMIA AT TERTIARY CARE HOSPITAL, KARACHI." Biological and Clinical Sciences Research Journal 2024, no. 1 (2024): 669. http://dx.doi.org/10.54112/bcsrj.v2024i1.669.

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Anemia is the most prevalent haematological condition in newborns and children. A deficiency of iron necessary for synthesizing haemoglobin causes it. This study used the iron profile as the gold standard for patients with hypochromic microcytic anemia at a tertiary care hospital in Karachi to assess the Mentzer index's diagnostic accuracy for iron-deficient anemia. From January 2021 to December 2022, a cross-sectional descriptive study was conducted in the Department of Pediatrics, NICH, Karachi. With the patient's explicit consent, data was prospectively collected. Those who satisfied the di

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Qurat-ul-ain Asghar, Ghadir Ali, Muhammad Khurram, et al. "DIAGNOSTIC VALUE OF MENTZER INDEX FOR THALASSEMIA PREDICTION IN SUSPECTED PATIENTS OF PUNJAB." JOURNAL OF MICROBIOLOGY AND MOLECULAR GENETICS 4, no. 3 (2023): 56–69. http://dx.doi.org/10.52700/jmmg.v4i3.113.

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Thalassemia is a genetic disease and became a worldwide problem. Worldwide, about 3-8% of population are suffered from beta thalassemia. The aim of this study was to use Mentzer index for predicting the beta thalassemia patients in the population of Punjab. This was a retrospective study conducted between 2021 September to 2022 June. In the current study, about n=1000 patients were selected to screen out for beta thalassemia in which n=607 were positive while the remaining were negative for the disease. Their sample were analyzed by using ABACUS 380 hematology analyzer for CBCs and hemoglobinp

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Surjawan, Yenny, Hwee Lian Tan, Rahajuningsih Dharma Setiabudy, and Wiwik Rositawati. "Early Screening of Hemoglobinopathy in Indonesia Using Erythrocyte Indices." Indonesian Biomedical Journal 9, no. 2 (2017): 99. http://dx.doi.org/10.18585/inabj.v9i2.313.

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BACKGROUND: The mutation spectrums of hemoglobinopathy are different among populations that yield a different result of erythrocyte indices. Calculation of erythrocyte indices with some formula has been reported to differentiate between hemoglobinopathy and non-hemoglobinopathy, but its cut-off should be recalculated specific for each population to gain a better sensitivity and specificity. We aimed to evaluate red blood cell count (RBC), Mentzer index, red cell distribution width (RDW), RDW index (RDWI), Shine and Lal index (S&L) and Green and King index (G&K) to screen hemoglobinopat

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Mutiawati, Vivi Keumala, and Adi Koesoema Aman. "Profile Laboratory of Thalassemia in the General Hospital Dr. Zainoel Abidin Banda Aceh." INDONESIAN JOURNAL OF CLINICAL PATHOLOGY AND MEDICAL LABORATORY 31, no. 1 (2024): 83–87. http://dx.doi.org/10.24293/ijcpml.v31i1.2218.

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Thalassemia refers to the globin gene abnormality that affects the a and b globin genes. A comprehensive peripheral blood laboratory examination, Mentzer index, blood morphology, and Hb analysis were all performed on every patient with thalassemia who attended treatment as part of this analytical observational study. This research aims to know the profile of laboratory examinations of thalassemia patients in the Dr. Zainoel Abidin General Hospital (RSUZA) Banda Aceh. The study's target population was 547 individuals, with 278 males and 269 females making up the male and female split, respectiv

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Sahiratmadja, Edhyana, Ani Melani Maskoen, Lelani Reniarti та Delita Prihatni. "Erythrocyte Indices MCV and/or MCH as First Round Screening Followed by Hb-analysis for β-thalassemia Carrier State". Indonesian Biomedical Journal 14, № 3 (2022): 282–8. http://dx.doi.org/10.18585/inabj.v14i3.1960.

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BACKGROUND: Being located in the global thalassemia belt area, Indonesia is estimated harboring about 10% thalassemia carriers; however, screening program is still diversely scattered across the country. Numerous erythrocyte indices have been introduced to help identifying thalassemia carriers with contradictory results. Therefore, this study had compared the use of mean corpuscular volume (MCV) and/or mean corpuscular hemoglobin (MCH) values and the most erythrocyte indices used in Indonesia which were Mentzer Index (MI) and Shine & Lal Index (SLI), as a first attempt in a mass screening

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Kumari, Sarita, Princee Seth, and Hanslata Gehlot. "Antenatal screening for thalassemia carrier at tertiary care centre." International Journal of Reproduction, Contraception, Obstetrics and Gynecology 12, no. 8 (2023): 2481–85. http://dx.doi.org/10.18203/2320-1770.ijrcog20232295.

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Background: Thalassemia syndromes are the commonest genetic disorders of blood and constitute a vast public health problem with 2.78 to 4% prevalence in India. The most effective and feasible approach to reduce the incidence of thalassemia major is implementation of carrier screening program to screen the antenatal women in early pregnancy. Methods: Institutional based cross sectional observational study was conducted. We screened 400 antenatal women by performing preliminary test red cell indices, Mentzer index and confirmatory test by high performance liquid chromatography. Husbands of posit

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