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Journal articles on the topic 'Mesylate Rasagilina'

Author: Grafiati

Published: 4 June 2021

Last updated: 5 February 2022

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1

Zhang, Lina, Zhiqin Zhang, Yangmei Chen, et al. "Efficacy and safety of rasagiline as an adjunct to levodopa treatment in Chinese patients with Parkinson's disease: a randomized, double-blind, parallel-controlled, multi-centre trial." International Journal of Neuropsychopharmacology 16, no. 7 (2013): 1529–37. http://dx.doi.org/10.1017/s1461145713000175.

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Abstract Rasagiline mesylate is a highly potent, selective and irreversible monoamine oxidase type B (MAOB) inhibitor and is effective as monotherapy or adjunct to levodopa for patients with Parkinson's disease (PD). However, few studies have evaluated the efficacy and safety of rasagiline in the Chinese population. This study was designed to investigate the safety and efficacy of rasagiline as adjunctive therapy to levodopa treatment in Chinese PD patients. This was a randomized, double-blind, placebo-controlled, parallel-group, multi-centre trial conducted over a 12-wk period that enrolled 2

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2

Kathirvel, Singaram, Suggala Venkata Satyanarayana, and Garikapati Devalarao. "Development and Validation of a Stability-Indicating HPTLC Method for Analysis of Rasagiline Mesylate in the Bulk Drug and Tablet Dosage Form." Chromatography Research International 2012 (February 6, 2012): 1–6. http://dx.doi.org/10.1155/2012/273604.

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A simple and sensitive thin-layer chromatographic method has been established for analysis of rasagiline mesylate in pharmaceutical dosage form. Chromatography on silica gel 60 F254 plates with 6 : 1 : 2(v/v/v) butanol-methanol water as mobile phase furnished compact spots at Rf 0.76±0.01. Densitometric analysis was performed at 254 nm. To show the specificity of the method, rasagiline mesylate was subjected to acid, base, neutral hydrolysis, oxidation, photolysis, and thermal decomposition, and the peaks of degradation products were well resolved from that of the pure drug. Linear regression

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3

Başköse, U., Sevgi Bayarı, Semran Sağlam, and Hacı Özışık. "Theoretical investigation of the Anti-Parkinson drug rasagiline and its salts: conformations and infrared spectra." Open Chemistry 10, no. 2 (2012): 395–406. http://dx.doi.org/10.2478/s11532-011-0162-z.

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AbstractThe conformational analysis of rasagiline [N-propargyl-1(R)-aminoindan] was performed by the density functional theory (DFT) B3LYP method using the 6–31++G (d,p) basis set. A single point energy calculations based on the B3LYP optimized geometries were also performed at MP2/6-31++G (d, p) level. The vibrational frequencies of the most stable conformer of rasagiline was calculated at the B3LYP level and vibrational assignments were made for normal modes on the basis of scaled quantum mechanical force field (SQM) method. The influence of mesylate and ethanedisulfonate salts on the geomet

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4

Raj, Napa Delhi, Abburu Rukmangada Rao, and Chusena Narasimharaju Bhimanadhuni. "Development of RP-HPLC method for the estimation of Rasagiline mesylate in bulk and tablet dosage forms." International Current Pharmaceutical Journal 1, no. 9 (2012): 285–87. http://dx.doi.org/10.3329/icpj.v1i9.11620.

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A simple RP-HPLC method for the determination of Rasagiline Mesylate in bulk and tablet dosage form was developed. Numerous HPLC conditions were tested for determination of rasagiline. The best result was achieved by using Purosphere star RP-18, (150×4.6mm), 5µm column and a mobile phase consisting of Potassium Orthophosphate: Acetonitrile (60:40 v/v) adjusted to pH 7.0(±0.05) with Ammonia solution, a flow rate of 1.5 ml/min with ultraviolet detection at 210nm. The correlation coefficients for calibration curves within the detection range of 5-30µg/ml were 0.9993. The within and between-day pr

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5

Fonseca, Thiago de Sousa, Marcos Reinaldo da Silva, Maria da Conceição Ferreira de Oliveira, Telma Leda Gomes de Lemos, Ricardo de Araújo Marques, and Marcos Carlos de Mattos. "Chemoenzymatic synthesis of rasagiline mesylate using lipases." Applied Catalysis A: General 492 (February 2015): 76–82. http://dx.doi.org/10.1016/j.apcata.2014.12.015.

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6

Hussar, Daniel A. "New Drugs: Rasagiline Mesylate, Conivaptan Hydrochloride, and Sunitinib Malate." Journal of the American Pharmacists Association 46, no. 5 (2006): 650–55. http://dx.doi.org/10.1331/1544-3191.46.5.650.hussar.

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7

Müller, Thomas. "Pharmacokinetic/pharmacodynamic evaluation of rasagiline mesylate for Parkinson’s disease." Expert Opinion on Drug Metabolism & Toxicology 10, no. 10 (2014): 1423–32. http://dx.doi.org/10.1517/17425255.2014.943182.

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8

Genina, Natalja, Eva Maria Janßen, Armin Breitenbach, Jörg Breitkreutz, and Niklas Sandler. "Evaluation of different substrates for inkjet printing of rasagiline mesylate." European Journal of Pharmaceutics and Biopharmaceutics 85, no. 3 (2013): 1075–83. http://dx.doi.org/10.1016/j.ejpb.2013.03.017.

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9

FERNÁNDEZ, MARCOS, EMILIA BARCIA, and SOFÍA NEGRO. "EFFECT OF GAMMA-IRRADIATION ON BIODEGRADABLE MICROSPHERES LOADED WITH RASAGILINE MESYLATE." Journal of the Chilean Chemical Society 61, no. 4 (2016): 3177–80. http://dx.doi.org/10.4067/s0717-97072016000400005.

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10

Nagai, Masahiro, and Nobutaka Hattori. "Pharmacological properties and clinical efficacy of rasagiline mesylate (Azilect^®)." Folia Pharmacologica Japonica 155, no. 3 (2020): 187–94. http://dx.doi.org/10.1254/fpj.19146.

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11

Varela, Aimilia, Manolis Mavroidis, Michalis Katsimpoulas, et al. "The neuroprotective agent Rasagiline mesylate attenuates cardiac remodeling after experimental myocardial infarction." ESC Heart Failure 4, no. 3 (2017): 331–40. http://dx.doi.org/10.1002/ehf2.12140.

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12

Ravi, P. R., N. Aditya, S. Patil, and L. Cherian. "Nasalin-situgels for delivery of rasagiline mesylate: improvement in bioavailability and brain localization." Drug Delivery 22, no. 7 (2013): 903–10. http://dx.doi.org/10.3109/10717544.2013.860501.

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13

Varela, Aimilia, Manolis Mavroidis, Michalis Katsiboulas, et al. "0161: The neuroprotective agent rasagiline mesylate attenuates cardiac remodeling after experimental myocardial infarction." Archives of Cardiovascular Diseases Supplements 7, no. 1 (2015): 83–84. http://dx.doi.org/10.1016/s1878-6480(15)71727-1.

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14

Pingili, Ravindrababu, Sridhar Vemulapalli, Surya Sandeep Mullapudi, Siddhartha Nuthakki, Sivaprasad Pendyala, and Naveenbabu Kilaru. "Pharmacokinetic interaction study between flavanones (hesperetin, naringenin) and rasagiline mesylate in wistar rats." Drug Development and Industrial Pharmacy 42, no. 7 (2015): 1110–17. http://dx.doi.org/10.3109/03639045.2015.1115868.

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15

Kunasekaran, Viveksarathi, and Kannan Krishnamoorthy. "Experimental Design for the Optimization of Nanoscale Solid Lipid Particles Containing Rasagiline Mesylate." Journal of Young Pharmacists 7, no. 4 (2015): 285–95. http://dx.doi.org/10.5530/jyp.2015.4.2.

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16

Reichmann, H. "Der Monoaminooxidase-B-Hemmer der zweiten Generation, Rasagilin Mesylat (Azilect®)." Aktuelle Neurologie 32, no. 10 (2005): 589–93. http://dx.doi.org/10.1055/s-2005-867007.

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17

Kannan, K., and K. Viveksarathi. "Effect of the moist-heat sterilization on fabricated nanoscale solid lipid particles containing rasagiline mesylate." International Journal of Pharmaceutical Investigation 5, no. 2 (2015): 87. http://dx.doi.org/10.4103/2230-973x.153383.

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18

Meier-Davis, Susan R., Kevin Dines, Fatima M. Arjmand, et al. "Comparison of oral and transdermal administration of rasagiline mesylate on human melanoma tumor growthin vivo." Cutaneous and Ocular Toxicology 31, no. 4 (2012): 312–17. http://dx.doi.org/10.3109/15569527.2012.676119.

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19

CHENNAIAH, M., T. VEERAIAH, T. CHARAN SINGH, and G. VENKATESHWARLU. "EXTRACTIVE SPECTROPHOTOMETRY METHODS FOR DETERMINATION OF RASAGILINE MESYLATE IN PHARMACEUTICAL FORMULATIONS USING ACIDIC TRIPHENYLMETHANE DYES." Journal of the Chilean Chemical Society 56, no. 4 (2011): 926–29. http://dx.doi.org/10.4067/s0717-97072011000400022.

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20

Nirogi, Ramakrishna, Mallikarjuna Rao Doguparthi, Bujjibabu Lingavarapu, Kavitha Rani Thota, and NK Sivasekhar Yarra. "Reverse Phase High Performance Liquid Chromatographic Method for Separation of R-Rasagiline Mesylate from S-Isomer." Asian Journal of Chemistry 27, no. 1 (2015): 85–88. http://dx.doi.org/10.14233/ajchem.2015.16712.

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21

Hussain, Sayyed, Amit Gosar, and Tabrez Shaikh. "Development and Validation of UV-Spectrophoto-metric Method for Determination of Palladium Content in Rasagiline Mesylate." British Journal of Pharmaceutical Research 15, no. 4 (2017): 1–7. http://dx.doi.org/10.9734/bjpr/2017/32254.

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22

Shelke, P., and A. Chandewar. "Study of Stress Degradation Behavior of Rasagiline Mesylate Under Hydrolytic Conditions by High Performance Liquid Chromatography." Drug Research 64, no. 04 (2013): 182–85. http://dx.doi.org/10.1055/s-0033-1355332.

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23

Fernández, M., E. Barcia, A. Fernández-Carballido, L. Garcia, K. Slowing, and S. Negro. "Controlled release of rasagiline mesylate promotes neuroprotection in a rotenone-induced advanced model of Parkinson's disease." International Journal of Pharmaceutics 438, no. 1-2 (2012): 266–78. http://dx.doi.org/10.1016/j.ijpharm.2012.09.024.

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24

Janapareddi, Krishnaveni, and Anilgoud Kandhula. "Development and Ex vivo evaluation of Rasagiline Mesylate mucoadhesive microemulsion for intranasal delivery using Box-Behnken design." International Journal of Bio-Pharma Research 8, no. 3 (2019): 2514–22. http://dx.doi.org/10.21746/aps.2018.8.3.4.

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Rasagiline mesylate (RM), an irreversible, selective inhibitor of MAO-B enzyme, is used in the treatment of Parkinson’s disease as oral tablets. It has low oral bioavailability (36%) due to hepatic first pass metabolism. Oral route of administration is associated with nausea and vomiting. Hence present research work was aimed to develop intranasal RM- loaded mucoadhesive microemulsions for brain targeting via olfactory pathway. The microemulsions were developed using Box Behnken design and evaluated for globule size, PDI, Zeta potential, pH, viscosity and ex vivo permeation on excised porcine

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25

Sevim, S., and N. Erk. "Applications of high performance liquid chromatographic and spectrophotometric techniques for determination of rasagiline mesylate in dosage forms." Journal of Analytical Chemistry 70, no. 5 (2015): 600–607. http://dx.doi.org/10.1134/s1061934815050135.

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26

Jiang, Ying, Xuemei Zhang, Hongjie Mu, et al. "Preparation and evaluation of injectable Rasagiline mesylate dual-controlled drug delivery system for the treatment of Parkinson’s disease." Drug Delivery 25, no. 1 (2017): 143–52. http://dx.doi.org/10.1080/10717544.2017.1419514.

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27

Wake, Prashant S., and M. D. Kshirsagar. "Compatibility study In-vitro drug release Study of Solid Lipid Nanoparticle Based Transdermal Drug Delivery System for Rasagiline Mesylate." Asian Journal of Research in Pharmaceutical Science 7, no. 2 (2017): 92. http://dx.doi.org/10.5958/2231-5659.2017.00014.5.

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28

Patel, Pratikkumar, Anuradha Pol, Dhaval Kalaria, Abhijit A. Date, Yogeshvar Kalia, and Vandana Patravale. "Microemulsion-based gel for the transdermal delivery of rasagiline mesylate: In vitro and in vivo assessment for Parkinson’s therapy." European Journal of Pharmaceutics and Biopharmaceutics 165 (August 2021): 66–74. http://dx.doi.org/10.1016/j.ejpb.2021.04.026.

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29

Fernández, Marcos, Emilia Barcia, and Sofía Negro. "Development and validation of a reverse phase liquid chromatography method for the quantification of rasagiline mesylate in biodegradable PLGA microspheres." Journal of Pharmaceutical and Biomedical Analysis 49, no. 5 (2009): 1185–91. http://dx.doi.org/10.1016/j.jpba.2009.02.031.

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30

Ravi, P. R., N. Aditya, L. Cherian, and S. Patil. "LC Method for Determination of Rasagiline Mesylate in Different Plasma Matrices and its Application to Oral Pharmacokinetic Study in Rabbits." Journal of Chromatographic Science 51, no. 1 (2012): 1–7. http://dx.doi.org/10.1093/chromsci/bms096.

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31

Bali, Nikhil R., Mahesh P. Shinde, Shahadev B. Rathod, and Pramod S. Salve. "Enhanced transdermal permeation of rasagiline mesylate nanoparticles: design, optimization, and effect of binary combinations of solvent systems across biological membrane." International Journal of Polymeric Materials and Polymeric Biomaterials 70, no. 3 (2020): 158–73. http://dx.doi.org/10.1080/00914037.2019.1706507.

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32

Rabey, J. M., I. Sagi, M. Huberman, et al. "Rasagiline Mesylate, a New Mao-B Inhibitor for the Treatment of Parkinson's Disease: A Double-Blind Study as Adjunctive Therapy to Levodopa." Clinical Neuropharmacology 23, no. 6 (2000): 324–30. http://dx.doi.org/10.1097/00002826-200011000-00005.

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33

Krishnamoorthy, Kannan, and Viveksarathi Kunasekaran. "Multi criteria decision making to select the best method for the preparation of solid lipid nanoparticles of rasagiline mesylate using analytic hierarchy process." Journal of Advanced Pharmaceutical Technology & Research 5, no. 3 (2014): 115. http://dx.doi.org/10.4103/2231-4040.137410.

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34

Sunil Reddy, P., K. Sudhakar Babu, and Navneet Kumar. "A Validated Normal Phase LC Method for Enantiomeric Separation of Rasagiline Mesylate and Its (S )-Enantiomer on Cellulose Derivative-Based Chiral Stationary Phase." Chirality 25, no. 6 (2013): 324–27. http://dx.doi.org/10.1002/chir.22150.

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35

Ozan TOKSOY, Mahmut, and Fahriye Figen TIRNAKSIZ. "Development of rasagiline mesylate loaded solid lipid nanoparticles in a thermosensitive mucoadhesive gel: Formulation design using DoE, in-vitro and ex-vivo characterization." Journal of Research in Pharmacy 25(5), no. 25(5) (2021): 695–707. http://dx.doi.org/10.29228/jrp.61.

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36

Patel, Riddhi, and Rajashree Mashru. "Development and Validation of Chemometric Assisted Methods and Stability Indicating RP-HPLC Method for Simultaneous Estimation of Rasagiline Mesylate and Pramipexole in Synthetic Mixture." Acta Scientific Pharmaceutical Sciences 3, no. 8 (2019): 154–68. http://dx.doi.org/10.31080/asps.2019.03.0359.

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37

Sunil Reddy, P., K. Sudhakar Babu, and N. Kumar. "Development and Validation of a Stability-Indicating RP-HPLC Method for the Simultaneous Estimation of Process Related Impurities and Degradation Products of Rasagiline Mesylate in Pharmaceutical Formulation." Journal of Chromatographic Science 51, no. 3 (2012): 242–49. http://dx.doi.org/10.1093/chromsci/bms134.

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38

Mandli, Vipulbhai, and Shailesh T. Prajapati. "Design, Development and Delivery of Rasagiline Mesylate from Monolithic Drug in Adhesive Matrix Patches." International Journal of Pharmaceutical Sciences and Drug Research, January 30, 2020, 65–72. http://dx.doi.org/10.25004/ijpsdr.2020.120111.

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The purpose of this research was to prepare and evaluate monolithic drug-in-adhesive type patches of Rasagiline Mesylate (RM) containing penetration enhancer and having seven day wear property. Preformulation studies like solubility in permeation enhancers, compatibility study, transmission study, uptake study and crystallization study of Rasagiline Mesylate in various pressure sensitive adhesive polymers were performed. Transdermal system was prepared by solvent casting method. The effects of various permeation enhancers (Propylene Glycol, Oleic Acid, Isopropyl Palmitate, and lauryl lactate)

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39

YGJ, Van Rijswick, Quesada MJ, and Van Os SHG. "Bioequivalence between Generic Rasagiline (As Tartrate) and Rasagiline (As Mesylate)." Journal of Bioequivalence Studies, September 2016. http://dx.doi.org/10.15744/2575-551x.2.104.

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40

"Quantification of rasagiline mesylate by stability indicating RP-HPLC method: Development and validation." Journal of Applied Pharmaceutical Science 9, no. 9 (2019): 59–65. http://dx.doi.org/10.7324/japs.2019.90908.

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41

Kunasekaran, Viveksarathi, and Kannan Krishnamoorthy. "Formulation and Evaluation of Nanoscale Solid Lipid Particles Containing a Hydrophilic Drug-Rasagiline Mesylate." Journal of Applied Pharmaceutical Science, 2016, 044–50. http://dx.doi.org/10.7324/japs.2016.60507.

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42

Rohith, G., and B. K. Satheesha Babu. "Influence of Chitosan Thioglycolic Acid Conjugate in improving bioavailability of an Antiparkinson drug; Rasagiline Mesylate from transdermal patch." Drug Development and Industrial Pharmacy, July 20, 2021, 1–45. http://dx.doi.org/10.1080/03639045.2021.1957919.

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43

H.I. Habib, Ibrahim. "Square Wave Voltammetric Determination of Rasagiline Mesylate on Hanging Mercury Drop Electrode and its application in Dosage Form and Biological Fluids." International Journal of Electrochemical Science, June 2016, 4802–11. http://dx.doi.org/10.20964/2016.06.64.

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44

"Development and validation of a new HPLC method with fluorescence detection for determination of Rasagiline Mesylate and its application to pharmaceutical dosage form." Egyptian Journal of Pure and Applied Science 55, no. 2 (2017): 9–15. http://dx.doi.org/10.21608/ejaps.2017.183757.

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