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Journal articles on the topic 'Met-car'

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1

Qin, Yuan, Anna Qin, Anna Musket, et al. "136 Targeting MET with chimeric antigen receptor T cells in hepatocellular carcinoma." Journal for ImmunoTherapy of Cancer 8, Suppl 3 (2020): A149. http://dx.doi.org/10.1136/jitc-2020-sitc2020.0136.

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BackgroundHepatocellular carcinoma (HCC) is the leading cause of cancer mortality worldwide. While HBV/HCV infection is the primary cause of HCC, overexpression of MET, the receptor of hepatocyte growth factor (HGF), occurs in 50% HCC patients, and is an indicator of poor prognosis. Although the multi-target MET tyrosine kinase inhibitor cabozantinib is FDA approved for treating advanced HCC, the long-term efficacy versus toxicity remains unknown. Our study is to develop specific MET-targeting chimeric antigen receptor T (CAR-T) cells for treating HCC with MET overexpression.MethodsBased on a
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2

van Heijnsbergen, Deniz, Michael A. Duncan, Gerard Meijer, and Gert von Helden. "Infrared spectroscopy of Ti8C12 `met-car' cations." Chemical Physics Letters 349, no. 3-4 (2001): 220–26. http://dx.doi.org/10.1016/s0009-2614(01)01230-1.

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3

Domingos, H. S. "Computational study of Met-Car analogue heterofullerenes." Modelling and Simulation in Materials Science and Engineering 14, no. 4 (2006): 637–46. http://dx.doi.org/10.1088/0965-0393/14/4/007.

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4

Stairs, J. R., K. M. Davis, S. J. Peppernick, and A. W. Castleman. "Delayed ionization of the zirconium Met-Car, Zr8C12." Journal of Chemical Physics 119, no. 15 (2003): 7857–63. http://dx.doi.org/10.1063/1.1605379.

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5

Ghaffarinejad, A. "Treasure paranoia and met - Amphetamine abuse." European Psychiatry 26, S2 (2011): 42. http://dx.doi.org/10.1016/s0924-9338(11)71753-9.

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Using metAmphetamine is going to be speared among young people in recent decade in our region.Cases of metAmphetamine induced psychosis are frequently admitted in our psychiatric hospital in Kerman city (Located in south - east of Iran). Hallucinations and paranoid delusions are well - known symptoms of met - psychosis.In this report we presented a 35 years old man with history of regular usage of drug in the past one year. He had persecutory delusions.His paranoid symptoms were interesting from a point of view. He bought a second - hand car, one year prior to his illness’ and at the same time
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6

Khan, Arshad. "Isomers of Neutral Ti Met-Car: A Theoretical Study." Journal of Physical Chemistry 99, no. 14 (1995): 4923–28. http://dx.doi.org/10.1021/j100014a009.

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7

BAUM, RUDY, and PAMELA ZURER. "Met-Car Formation Probed, Mixed Metal Species Also Detected." Chemical & Engineering News 72, no. 21 (1994): 35–36. http://dx.doi.org/10.1021/cen-v072n021.p035.

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8

Wang, Lai-Sheng, San Li, and Hongbin Wu. "Photoelectron Spectroscopy and Electronic Structure of Met-Car Ti8C12." Journal of Physical Chemistry 100, no. 50 (1996): 19211–14. http://dx.doi.org/10.1021/jp9630683.

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9

Thayaparan, Thivyan, Roseanna M. Petrovic, Daniela Y. Achkova, et al. "CAR T-cell immunotherapy of MET-expressing malignant mesothelioma." OncoImmunology 6, no. 12 (2017): e1363137. http://dx.doi.org/10.1080/2162402x.2017.1363137.

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10

Brock, L. R., and M. A. Duncan. "Near-Threshold Photoionization to Probe Neutral “Met-Car” Clusters." Journal of Physical Chemistry 100, no. 14 (1996): 5654–59. http://dx.doi.org/10.1021/jp953421p.

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11

Scott, Damon. "When the Motorman Mayor Met the Cable Car Ladies." Journal of Urban History 40, no. 1 (2013): 65–96. http://dx.doi.org/10.1177/0096144213503945.

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12

Varganov, Sergey A., and Mark S. Gordon. "Effects of strong electron correlations in Ti8C12 Met-Car." Chemical Physics 326, no. 1 (2006): 97–106. http://dx.doi.org/10.1016/j.chemphys.2005.12.021.

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13

Leskiw, B. D., K. L. Knappenberger, and A. W. Castleman. "Relaxation dynamics of the electronically excited vanadium Met–Car cluster." Journal of Chemical Physics 117, no. 18 (2002): 8321–26. http://dx.doi.org/10.1063/1.1512653.

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14

Domingos, H. S., and P. D. Bristowe. "On the stability of Met-Car analogue clusters in the solid state." Journal of Physics: Condensed Matter 15, no. 25 (2003): 4341–48. http://dx.doi.org/10.1088/0953-8984/15/25/305.

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15

Pearson, James T., Hamish P. Thambyah, Mark T. Waddingham та ін. "β-blockade prevents coronary macro- and microvascular dysfunction induced by a high salt diet and insulin resistance in the Goto–Kakizaki rat". Clinical Science 135, № 2 (2021): 327–46. http://dx.doi.org/10.1042/cs20201441.

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Abstract A high salt intake exacerbates insulin resistance, evoking hypertension due to systemic perivascular inflammation, oxidative-nitrosative stress and endothelial dysfunction. Angiotensin-converting enzyme inhibitor (ACEi) and angiotensin receptor blockers (ARBs) have been shown to abolish inflammation and redox stress but only partially restore endothelial function in mesenteric vessels. We investigated whether sympatho-adrenal overactivation evokes coronary vascular dysfunction when a high salt intake is combined with insulin resistance in male Goto–Kakizaki (GK) and Wistar rats treate
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16

Chicaybam, Leonardo, Martín H. Bonamino, Adriana Luckow Invitti, Patricia Bortman Rozenchan, Igor de Luna Vieira, and Bryan E. Strauss. "Overhauling CAR T Cells to Improve Efficacy, Safety and Cost." Cancers 12, no. 9 (2020): 2360. http://dx.doi.org/10.3390/cancers12092360.

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Gene therapy is now surpassing 30 years of clinical experience and in that time a variety of approaches has been applied for the treatment of a wide range of pathologies. While the promise of gene therapy was over-stated in the 1990’s, the following decades were met with polar extremes between demonstrable success and devastating setbacks. Currently, the field of gene therapy is enjoying the rewards of overcoming the hurdles that come with turning new ideas into safe and reliable treatments, including for cancer. Among these modalities, the modification of T cells with chimeric antigen recepto
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17

Wu, Xianshi, Chengwu Wei, Cuiling Pan, Ying Duan, and Kehe Huang. "Regulation of expression and activity of selenoenzymes by different forms and concentrations of selenium in primary cultured chicken hepatocytes." British Journal of Nutrition 104, no. 11 (2010): 1605–12. http://dx.doi.org/10.1017/s0007114510002643.

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The expression and activity of selenoenzymes are regulated by Se. In the present study, the effects of different forms and concentrations of Se on the regulation of glutathione peroxidase (GPx) activity and phospholipid hydroperoxide GPx (GPx4) and type I deiodinase (D1) mRNA levels in chicken hepatocytes were evaluated. Primary cultured chicken hepatocyte monolayers derived from male White Leghorn chickens (aged 30–40 d) were incubated for 24 h with 0 (control), 0·5, 1, 1·5, 2, 3, 4 or 5 μmol/l of Se supplied as dl-selenomethionine (Se-Met), κ-selenocarrageenan (Se-Car) or sodium selenite (Na
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18

Spiegel, Jay Y., Shabnum Patel, Lori Muffly, et al. "CAR T cells with dual targeting of CD19 and CD22 in adult patients with recurrent or refractory B cell malignancies: a phase 1 trial." Nature Medicine 27, no. 8 (2021): 1419–31. http://dx.doi.org/10.1038/s41591-021-01436-0.

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AbstractDespite impressive progress, more than 50% of patients treated with CD19-targeting chimeric antigen receptor T cells (CAR19) experience progressive disease. Ten of 16 patients with large B cell lymphoma (LBCL) with progressive disease after CAR19 treatment had absent or low CD19. Lower surface CD19 density pretreatment was associated with progressive disease. To prevent relapse with CD19− or CD19lo disease, we tested a bispecific CAR targeting CD19 and/or CD22 (CD19-22.BB.z-CAR) in a phase I clinical trial (NCT03233854) of adults with relapsed/refractory B cell acute lymphoblastic leuk
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19

BINNENHEI, CARSTEN. "IMPLEMENTATION OF ENDOMORPHISMS OF THE CAR ALGEBRA." Reviews in Mathematical Physics 07, no. 06 (1995): 833–69. http://dx.doi.org/10.1142/s0129055x95000323.

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The implementation of non-surjective Bogoliubov transformations in Fock states over CAR algebras is investigated. Such a transformation is implementable by a Hilbert space of isometries if and only if the well-known Shale-Stinespring condition is met. In this case, the dimension of the implementing Hilbert space equals the square root of the Watatani index of the associated inclusion of CAR algebras, and both are determined by the Fredholm index of the corresponding one-particle operator. Explicit expressions for the implementing operators are obtained, and the connected components of the semi
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20

Tang, Pei, and Ji Sheng Xia. "Finite Element Analysis of Car's Sub-Frame." Applied Mechanics and Materials 651-653 (September 2014): 733–37. http://dx.doi.org/10.4028/www.scientific.net/amm.651-653.733.

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This paper studied the sub-frame of car. To optimize the design of the sub-frame of car, the finite element analysis was applied to the sub-frame.Through the static analysis, it found that the yield maximum stress is greater than the vice stress of frame material. The result showed that the static strength of sub-frame met the requirements.The rationality of the design of the side frame was verified. The twelve order modal parameters of sub-frame were analyzed.
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Mao, Ping Huai, Shuai Zhang, Li Bao Wang, and Yi Lin Mao. "Analysis of Lightweight Extension Support Coal Mine Car Loader." Applied Mechanics and Materials 687-691 (November 2014): 593–96. http://dx.doi.org/10.4028/www.scientific.net/amm.687-691.593.

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Horizontal support extending loader vehicle is used in coal mine, whose main role is to play a supportive role in belt transport unit. When the support car is pulled by tractor or pushed by motor vehicle, energy consumption is high with its own excessive weight. The car lightweight design is carried out through structural designing and material changing. Lightweight design has met the requirements after analysis. Lightweight design for support vehicle is not only to achieve the purpose of energy conservation, but also make the support vehicles assembling easily and get a good effect.
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22

Fitzek, F., R. H. Rasshofer, and E. M. Biebl. "Comparison of matching layers for automotive radome design." Advances in Radio Science 8 (September 30, 2010): 49–54. http://dx.doi.org/10.5194/ars-8-49-2010.

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Abstract. Hidden integration of 79 GHz sensors behind plastic and painted fascia represents a challenging task since both electromagnetic and car body design constraints have to be met. This paper compares different possibilities for low-cost integration of radar sensors. Based on a model for stratified media, a study of the most important parameters such as bandwidth, angle and tolerances is shown. Our results suggest that for plastic fascia, the requirements of future radar sensors can be met with low-cost matching. Even with metallic paints, the requirements imposed by modern 79 GHz radar s
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23

Balfanz, Henry B., and Brittany Verran. "Alma Chrysler Jeep Dodge Ram: Home Of BUDDY, The Four Legged Greeter." Journal of Business Case Studies (JBCS) 11, no. 1 (2015): 35–40. http://dx.doi.org/10.19030/jbcs.v11i1.9052.

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This is a case about a couple who met in college, eventually reconnected and married years later, and returned to the general area of where they met to own and operate a small town Michigan car dealership. Both have much experience in the automotive sales industry. The automobile business is evolving and deciding which promotional mix elements will work best for them is the challenge. As they are busy operating the dealership day to day, it is not always easy to find the time to plan strategy for the future. The dealership is far from reaching its sales potential; attaining the proper number o
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24

Ganji, Masoud Darvish, A. Fereidoon, Azadeh Khosravi, Nasim Ahmadian, and Sanaz Mohammad zadeh. "Adsorption of hydrogen molecules onto Li-decorated titanium met-car cluster: A first-principles study." Physica E: Low-dimensional Systems and Nanostructures 46 (September 2012): 193–97. http://dx.doi.org/10.1016/j.physe.2012.09.010.

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25

Wingdes, Irawan, and Tri Widayanti. "PENERAPAN AHP DAN TOPSIS UNTUK PENILAIAN KELAYAKAN KREDIT PADA BPR CENTRADANA KAPUAS PONTIANAK." CCIT Journal 10, no. 2 (2017): 255–68. http://dx.doi.org/10.33050/ccit.v10i2.546.

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Financing for business or consumption is one of the main purpose of a bank. BPR is mini part of Indonesian banking system that functions like conventional banks with limited or smaller role. BPR also finances for car loans. In practice, when administrative assessments for car loan applications are not met, subjective assessment is needed to further assess car loan applications. The purpose of this study is to develop decision support for the latter problem. This study employs AHP and TOPSIS as decision support method. 5C’s are used for assesment which results in highest preference in Character
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26

Hinz, Tomasz, and Ryszard Lewkowicz. "Some selected methods and purpose of the low speed tests for estimation of the vehicle bumpers vulnerability to damage." Mechanik 90, no. 5-6 (2017): 476–79. http://dx.doi.org/10.17814/mechanik.2017.5-6.62.

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Presented are the worldwide applied methods of tests to vehicle bumpers under low speed impact conditions. Identified are the purpose of such tests with essential requirements to be met in their performance procedure specified. Also described is rig test to the car bumpers as an alternative issue to the most popular procedures.
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27

Karavayev, Vladimir Mikhaylovich. "Structural circumstances in the main types of fatal concomitant injury in children." Pediatrician (St. Petersburg) 5, no. 3 (2014): 58–63. http://dx.doi.org/10.17816/ped5358-63.

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On the material of forensic research 284 corpses of children (108 own observations, 176 archive acts), died as a result of falling from height, hitting a moving car, drive to the wheels and the injury in a car, a study of the structure damage. Investigated the frequency and distribution of damage to the skin, skeletal and organ separate areas of the body, carried out the combined assessment of the extent of the damage when the considered variants of the circumstances of the injury. It is established that the children injured in the car to head injury in various manifestations, found in 100 % o
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28

Jilek, Petr, and Jan Němec. "System for Changing the Radial Response on Car Wheels." Acta Universitatis Agriculturae et Silviculturae Mendelianae Brunensis 68, no. 1 (2020): 39–47. http://dx.doi.org/10.11118/actaun202068010039.

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The paper deals with the possibilities of change in adhesion force for experimental measurement on a road vehicle. The article deals with the ways in which the road vehicle can be brought to skid limit while driving at a safe speed. These are two newly designed systems (SlideWheel and Alternative SkidCar) to complement the experimental car. Both systems allow for the reduction of the adhesion force on car wheels, depending on the reduction of radial force transmitted by the car wheel. Their main difference is in the spatial arrangement and in the method of attachment to a car. The wheel units
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29

Deng, H. T., K. P. Kerns та A. W. Castleman. "Studies of Met-Car Adducts: Ti8C12+(M)n(M = Halogens, π-Bonding Molecules, and Polar Molecules)". Journal of the American Chemical Society 118, № 2 (1996): 446–50. http://dx.doi.org/10.1021/ja9515359.

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30

Rampersaud, Andy, Nicholas J. Lodato, Aram Shin, and David J. Waxman. "Widespread Epigenetic Changes to the Enhancer Landscape of Mouse Liver Induced by a Specific Xenobiotic Agonist Ligand of the Nuclear Receptor CAR." Toxicological Sciences 171, no. 2 (2019): 315–38. http://dx.doi.org/10.1093/toxsci/kfz148.

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AbstractConstitutive androstane receptor (CAR) (Nr1i3), a liver nuclear receptor and xenobiotic sensor, induces drug, steroid, and lipid metabolism and dysregulates genes linked to hepatocellular carcinogenesis, but its impact on the liver epigenome is poorly understood. TCPOBOP (1, 4-bis-[2-(3, 5-dichloropyridyloxy)]benzene), a halogenated xenochemical and highly specific CAR agonist ligand, induces localized chromatin opening or closing at several thousand mouse liver genomic regions, discovered as differential DNase-hypersensitive sites (ΔDHS). Active enhancer and promoter histone marks ind
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Brackelaire, Jean-Luc. "Changer pour rire. Les relations de plaisanterie des Tarahumaras : figure et mesure du changement." Articles hors thème 17, no. 3 (2003): 125–40. http://dx.doi.org/10.7202/015279ar.

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Résumé Changer pour rire Les relations de plaisanterie des Tarahumaras : figure et mesure du changement L'auteur interroge la parenté à plaisanteries à partir du cas précis des Tarahumaras et donc sous les traits singuliers qu'ils lui donnent. Il tente de cerner les processus spécifiquement humains qu'elle met en œuvre et où elle peut trouver son explication. Après une présentation du phénomène, celui-ci est déconstruit sur deux plans, celui de la société, car il implique la parenté et le changement, et celui du droit, car il s'agit d'une transgression mesurée des règles. Il est appréhendé fin
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Morisse, Benjamin. "The Implementation Of Brand Standards In Franchised Retailing: The Field Of Car Dealerships." Journal of Applied Business Research (JABR) 29, no. 4 (2013): 991. http://dx.doi.org/10.19030/jabr.v29i4.7910.

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The management of franchisedretailing networks often involves the implementation of brand standardsthroughout the dealership. However, these standards might not be met, whether becauseof the dealers management of its own assets or because of the customer contactstaffs behavior towards clients. This article analyses the dissonance betweenthe brands prescribed standards and staff behavior across retailers for thefield of car retailing. It offers management recommendations designed to bringstaff behavior closer in alignment with brands knowledge.
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33

Locke, Frederick Lundry, John Rossi, Sattva Swarup Neelapu, et al. "Product characteristics associated with in vivo expansion of anti-CD19 CAR T cells in patients treated with axicabtagene ciloleucel (axi-cel)." Journal of Clinical Oncology 35, no. 15_suppl (2017): 3023. http://dx.doi.org/10.1200/jco.2017.35.15_suppl.3023.

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3023 Background: Axi-cel (formerly KTE-C19) is an autologous anti-CD19 chimeric antigen receptor (CAR) T cell therapy. ZUMA-1 is a multicenter, registrational trial of axi-cel in patients (pts) with refractory aggressive non-Hodgkin lymphoma. In a prespecified interim analysis, ZUMA-1 met its primary endpoint, with a 76% objective response rate and a 47% complete response rate ( Blood 2016;128:LBA-6). Post-treatment CAR T cell blood levels were associated with objective response. Here, we describe novel associations between product characteristics and CAR T cell levels in pts. Methods: CAR T c
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34

de Briey, Laurent. "L’antinomie de l’action : Weil et Camus." Les ateliers de l'éthique 5, no. 2 (2018): 4–22. http://dx.doi.org/10.7202/1044311ar.

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Les pensées de l’action de Weil et de Camus se heurtent à une même antinomie : la volonté d’agir raisonnablement implique à la fois de renoncer à toute action, car une action ne peut être efficace que si elle est potentiellement violente, et d’agir, car s’abstenir de toute action signifie accepter la violence présente. L’agent doit dès lors justifier la violence qu’il met en oeuvre. En conséquence, cet article confronte la manière dont ces deux auteurs s’efforcent de résoudre cette difficulté. Une telle confrontation nous permet, d’une part, de trouver chez Weil les fondements philosophiques q
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35

Saputra, Agus, Wirdah Irawati, and Talbani Farlian. "PENGARUH CAPITAL ADEQUACY RATIO DAN NET INTEREST MARGIN TERHADAP NILAI PROFITABILITAS BANK UMUM NON DEVISA DI INDONESIA." Jurnal Ekonomi dan Pembangunan 9, no. 1 (2018): 31–39. http://dx.doi.org/10.22373/jep.v9i1.20.

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Penelitian ini bertujuan untuk menguji pengaruh antara variabel CapitalAdequacyRatio (CAR) dan Net Interest Margin, terhadap nilai Profitabilitas pada Bank Umum Non Devisa di Indonesia. Penelitian ini menggunakan data empiris dari direktori Kantor Otorita Jasa Keuangan melalui teknik purposive sampling. Ada 17 Bank yang diamati selama 3 tahun secara kuartal mulai tahun 2014 sampai tahun 2016. Peralatan analisis yang digunakan adalah Analisis Regresi Linear Berganda. Hasil penelitian menunjukkan bahwa Capital Adequacy Ratio (CAR) tidak berpengaruh terhadap nilai profitabilitas Bank Umum Non Dev
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Lightstone, James M., Melissa J. Patterson, Ping Liu, and Michael G. White. "Gas-Phase Reactivity of the Ti8C12+Met-car with Triatomic Sulfur-Containing Molecules: CS2, SCO, and SO2." Journal of Physical Chemistry A 110, no. 10 (2006): 3505–13. http://dx.doi.org/10.1021/jp057277b.

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37

Baranowska, Irena, and Bartosz Kowalski. "An analytical procedure for the determination of different therapeutic drugs in surface waters." Water Science and Technology 60, no. 2 (2009): 449–58. http://dx.doi.org/10.2166/wst.2009.339.

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An analytical procedure for the determination of 10 drugs belonging to three different therapeutic groups was analysed. Several compounds were investigated which comprise of beta-blockers: sotalol (SOT), metoprolol (MET), propranolol (PRO), carvedilol (CAR); corticosteroids: prednisolone (PRE), dexamethasone (DEX); analgesic, non-steroidal anti-inflammatory (NSAID): paracetamol (PAR), metamizole (MTZ), aspirin (ASP) and ketoprofen (KET). Reversed-phase liquid chromatography with gradient elution, fluorescence (FL) and diode array detectors (DAD) was applied for the selective investigation of t
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38

Newman, Daniel. "Automobiles and Socioeconomic Sustainability." Transfers 7, no. 2 (2017): 100–106. http://dx.doi.org/10.3167/trans.2017.070207.

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This article argues for the establishment of a Mobility Bill of Rights. That the current car system is not sustainable in environmental terms has been much discussed in academic circles and is increasingly accepted in wider society, as reflected by governmental attempts at reform. The current trend for remodeling this car system largely involves the substitution of petrol/diesel for potentially more ecologically sound methods of powering the vehicles such as electricity. Attempts to reach environmental sustainability in this manner do little to impact social or economic sustainability and thus
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Saputra, Agus, Muhammad Arfan, and Mulia Saputra. "PENGARUH CAPITAL ADEQUACY RATIO, NET INTEREST MARGIN, LOAN TO DEPOSIT RATIO DAN NON PERFORMING LOAN TERHADAP PROFITABILITAS BANK UMUM NON DEVISA DI INDONESIA PERIODE 2014-2016." JURNAL PERSPEKTIF EKONOMI DARUSSALAM 4, no. 2 (2019): 199–212. http://dx.doi.org/10.24815/jped.v4i2.12573.

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This study examines the influence Capital Adequacy Ratio (CAR), Net Interest Margin (NIM), Loan to Deposit Ratio (LDR) and Non Performing Loan (NPL) toward Profitability for Non-Foreign Exchange Commercial Bank in Indonesia. This study uses empirical data on the directory of Financial Services Authority (Otorita Jasa Keuangan) through non probability sampling that met criteria of the research. There are 17 Banks observed for 3 years quarterly starting from 2014 until 2016. The analytical method using Multiple Linear Regression. The results show that Capital Adequacy Ratio (CAR) has unsignifica
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40

Kim, Rebecca H., Gabriela Plesa, Whitney Gladney, et al. "Effect of chimeric antigen receptor (CAR) T cells on clonal expansion of endogenous non-CAR T cells in patients (pts) with advanced solid cancer." Journal of Clinical Oncology 35, no. 15_suppl (2017): 3011. http://dx.doi.org/10.1200/jco.2017.35.15_suppl.3011.

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3011 Background: CAR T cells have produced remarkable responses in heme malignancies, but efficacy in solid cancers is limited. Poor in vivo persistence and heterogeneous expression of the CAR target on tumors are potential barriers to the success of CAR T cell therapy. However, even with transient persistence, CAR T cells may elicit a “vaccine” effect by inducing cancer cell death and subsequent release of tumor antigens that could stimulate tumor-specific T cell activity. Methods: 6 pts with pancreatic ductal adenocarcinoma (PDAC) received repeated 3x per week intravenous (iv) infusions of m
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41

Stairs, J. R., K. M. Davis, and A. W. Castleman. "Metastable dissociation of the zirconium Met-Car, Zr8C12, and connections to the production of the delayed atomic ion." Journal of Chemical Physics 117, no. 9 (2002): 4371–75. http://dx.doi.org/10.1063/1.1496475.

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42

Sahli, Brett, David Eckwright, Eric Darling, Patrick P. Gleason, and Joseph W. Leach. "Chimeric antigen receptor T-cell therapy real-world assessment of total cost of care and clinical events for the treatment of relapsed or refractory lymphoma." Journal of Clinical Oncology 39, no. 15_suppl (2021): e19500-e19500. http://dx.doi.org/10.1200/jco.2021.39.15_suppl.e19500.

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e19500 Background: Axicabtagene ciloleucel and tisagenlecleucel are FDA approved to treat relapsed or refractory B-cell lymphoma. CAR-T therapy involves a complex process of extraction, transfection, administration and management of adverse reactions such as cytokine release syndrome. Little has been established using real world evidence identifying CAR-T episode total cost of care (TCC) and post administration clinical events (CE) among the commercially insured population. Methods: Integrated pharmacy and medical claims were queried among a population of 15 million commercially insured member
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Miyajima, Ken, Naoya Fukushima, and Fumitaka Mafuné. "Reactivity of Niobium−Carbon Cluster Ions with Hydrogen Molecules in Relation to Formation Mechanism of Met−Car Cluster Ions." Journal of Physical Chemistry A 112, no. 26 (2008): 5774–76. http://dx.doi.org/10.1021/jp803247h.

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Chen, Cong, Yan-Mei Gu, Fan Zhang, et al. "Construction of PD1/CD28 chimeric-switch receptor enhances anti-tumor ability of c-Met CAR-T in gastric cancer." OncoImmunology 10, no. 1 (2021): 1901434. http://dx.doi.org/10.1080/2162402x.2021.1901434.

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Sunaryo, Deni. "The Effect Of Capital Adequacy Ratio (CAR), Net Interest Margin (NIM), Non-Performing Loan (NPL), and Loan To Deposit Ratio (LDR) Against Return On Asset (ROA) In General Banks In Southeast Asia 2012-2018." Ilomata International Journal of Management 1, no. 4 (2020): 149–58. http://dx.doi.org/10.52728/ijjm.v1i4.110.

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This study aims to determine the effect of Capital Adequacy Ratio (CAR), Net Interest Margin (NIM), Non Performing Loan (NPL), dan Loan to Deposit Ratio (LDR) in the Return On Asset (ROA) on the Commercial Banks in Southeast Asia in 2012-2018. The independent variabel used in this study is Capital Adequacy Ratio (CAR), Net Interest Margin (NIM), Non Performing Loan (NPL), dan Loan to Deposit Ratio (LDR). The dependent variabel used is Return On Assets (ROA). The methode used in this study uses purposive sempling technique, using scondary and quantitative data. The results of the analysis show
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Wahnich, Sophie. "Idylle ou lucidité antiraciste, la commune humanité en question." ALTERNATIVE FRANCOPHONE 2, no. 6 (2020): 28–47. http://dx.doi.org/10.29173/af29383.

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Ces cinq dernières années, les écrivains, les cinéastes, commissaires d’exposition ont produit un discours sur la ségrégation nord américaine non seulement comme impossible à faire reculer, mais comme pratique qui témoigne d’une cruauté sans limitequi met en danger des corps noirs à la merci d’une haine puissante et incommensurable à la puissance du droit. Il n’y aurait ainsi plus d’imaginaire possible pour une commune humanité car ce commun conduit toujours à une domination destructrice. Les sentiments sont pervertis, les corps colonisés, les enfants assassinés ou emprisonnés. La puissance ét
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Nguyen, Huong Mai Thi, and Trương Tích Thiện. "Simulation of Naturally Ventilated Underground Car Park with CFD." Science & Technology Development Journal - Engineering and Technology 3, SI3 (2020): SI22—SI28. http://dx.doi.org/10.32508/stdjet.v3isi3.686.

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Nowadays, the speed of urbanization is increasing rapidly, so the urban land area is fully utilized to build high-rise buildings, apartments, and commercial centers, and thus, the car tunnel parking and basement parking basements also become more popular. However, apartment fire and explosion, especially car fire and explosion is an extremely important issue that must be concerned in construction design. Therefore, it is essential to design an effective ventilation system in the parking basement when a fire occurs an effective ventilation system for the tunnel is really necessary for basement
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Swiggers, Pierre. "Formes, fonctions et catégories linguistiques: Les principes de grammaire générale de Louis Hjelmslev." Linguistica 45, no. 1 (2005): 41–52. http://dx.doi.org/10.4312/linguistica.45.1.41-52.

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Quand, en 1928, Louis Hjelmslev publie ses Principes de grammaire générale, il s'inscrit dans un vaste processus d'élaboration d'une linguistique generale, qui per­ met de rattacher ces prémices d'une ceuvre qu'on associe aujourd'hui avec une école structuraliste spécifique - la glossématique -, aux travaux fondateurs de Saussure, de Jespersen, de Sapir. On pourrait parler de "insertion dans l'histoire des théories linguistiques", car, comme Saussure, Hjelmslev a senti la nécessité de for­ muler, pour la premiere fois, une theorie cohérente du langage et de repartir de zéro, tout en acceptant
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Rios, Guilherme. "Letters in a community organisation: a case of powerful literacy." DELTA: Documentação de Estudos em Lingüística Teórica e Aplicada 21, spe (2005): 105–28. http://dx.doi.org/10.1590/s0102-44502005000300008.

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In this paper I examine discourse in five letters written by executive members of a resident's association in the city of Brasilia, by integrating Critical Discourse Analysis and the New Literacy Studies. These letters were part of a campaign from the association to prevent students of a nearby college from parking their car in the residential street, since the overload of parked cars made difficult the flow of vehicles. A case is made on the efficacy of the discursive and semiotic resources drawn on the letters to have community aims met.
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Courtois, Martine. "Fonctions de l’ objet romanesque dans la première trilogie de Beckett." Samuel Beckett Today / Aujourd’hui 32, no. 2 (2020): 337–51. http://dx.doi.org/10.1163/18757405-03202013.

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Résumé Dans la première trilogie de Beckett, la dissociation de l’ inventaire et des histoires met en cause le statut des objets et en perturbe toutes les fonctions habituelles. Accessoire, attribut, indice, objet d’ échange ou de quête, objet de savoir, aucune de ces qualités ne se vérifie. Enfin, l’ échec de l’ illusion référentielle réduit l’ inventaire à une nomenclature, et l’ histoire à une narrativisation de la liste. Mais comme le langage ne peut éliminer les signifiés, le roman abstrait reste irréalisable, car la res resurgit toujours derrière le rien.
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