Academic literature on the topic 'Meta-analysis and systematic review'

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Dissertations / Theses on the topic "Meta-analysis and systematic review"

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Medeiros, Ana Cláudia Ponte. "Bisphosphonates-related adverse events: systematic review and meta-analysis." Master's thesis, Universidade da Beira Interior, 2012. http://hdl.handle.net/10400.6/1130.

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A osteoporose é uma doença esquelética sistémica e progressiva que leva a um aumento do risco de fraturas. Os bifosfonatos são a opção terapêutica de primeira linha. Apesar dos efeitos adversos gastrointestinais associados ao uso de bifosfonatos o seu perfil de segurança é favorável. Contudo, recentemente, a Agência Europeia do Medicamento (EMA) emitiu um alerta de segurança após relatos de um aumento do risco da incidência de fraturas atípicas do fémur associadas ao uso destes fármacos, o que pode questionar a relação benefício/ risco deste grupo terapêutico. Objetivo: realizar uma revisão si
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Alobaid, Abdulhakeem M. "Bariatric Surgery for Obesity: A Systematic Review and Meta-analysis." Thèse, Université d'Ottawa / University of Ottawa, 2013. http://hdl.handle.net/10393/24167.

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Obesity is the fifth leading cause of global deaths. The efficacy and safety of obesity treatment is still controversial. The objective of the thesis is to evaluate the efficacy and safety of bariatric surgery, through a systematic review of the current evidence and meta- analysis of important outcomes. Nineteen (19) randomized controlled trials (RCTs) with 1346 participants were included. Bariatric surgery resulted in greater weight loss when compared to non-surgical treatment. Weight loss was also associated with resolution and/or improvement of obesity related comorbidites such as diabetes,
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Pinkston, Sophie Wardle. "Insomnia and Cognitive Performance: A Systematic Review and Meta-Analysis." Thesis, University of North Texas, 2019. https://digital.library.unt.edu/ark:/67531/metadc1505168/.

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Daytime cognitive performance and sleep/wake cycles are strongly interrelated, and cognitive dysfunction has been extensively investigated in relation to insomnia. However, methods and outcomes vary widely by study, making comparison difficult without more systematic evaluation. Review of the literature reveals discrepant findings for the relationship between both subjective and objective measures of cognitive performance and insomnia. The current meta-analysis included 42 studies investigating the relationship between insomnia and cognitive performance. Results confirmed the discrepant nature
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Whiting, Penny F., Robert F. Wolff, Sohan Deshpande, et al. "Cannabinoids for Medical Use A Systematic Review and Meta-analysis." American Medical Association, 2015. http://hdl.handle.net/10757/558499.

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Importance Cannabis and cannabinoid drugs are widely used to treat disease or alleviate symptoms, but their efficacy for specific indications is not clear. Objective To conduct a systematic review of the benefits and adverse events (AEs) of cannabinoids. Data Sources Twenty-eight databases from inception to April 2015. Study Selection Randomized clinical trials of cannabinoids for the following indications: nausea and vomiting due to chemotherapy, appetite stimulation in HIV/AIDS, chronic pain, spasticity due to multiple sclerosis or paraplegia, depression, anxiety disorder, sleep
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Vesterinen, Hanna Mikaela. "Systematic review and meta-analysis of experimental multiple sclerosis studies." Thesis, University of Edinburgh, 2013. http://hdl.handle.net/1842/11720.

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Background: Multiple sclerosis (MS) is the most common cause of disability in young people and yet there are no interventions available which reliably alter disease progression. This is despite several decades of research using the most common animal model of multiple sclerosis, experimental autoimmune encephalomyelitis (EAE). There is now emerging evidence across the neurosciences to suggest that limited internal validity (measures to reduce bias) and external validity (e.g. using a clinically relevant animal model) may influence the translational success. Aim and objectives: To provide an un
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Lee, Jin-Hyung. "The Effects of Music on Pain: A Review of Systematic Reviews and Meta-Analysis." Diss., Temple University Libraries, 2015. http://cdm16002.contentdm.oclc.org/cdm/ref/collection/p245801coll10/id/320333.

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Music Therapy<br>Ph.D.<br>The purpose of this study was twofold: to critically review existing systematic reviews and meta-analyses on the topic of music and pain; and to systematically review and conduct a meta-analysis of clinical trials investigating the effect of music on pain encompassing a wide range of medical diagnoses, settings, age groups, and types of pain. For the review of systematic reviews, the author conducted a comprehensive search and identified 14 systematic reviews and meta-analyses. These studies were critically analyzed to present a comprehensive overview of findings, to
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Jafari, Yalda. "Point-of-care tests for syphilis: meta-analysis and systematic review." Thesis, McGill University, 2011. http://digitool.Library.McGill.CA:80/R/?func=dbin-jump-full&object_id=104812.

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Background: The World Health Organization estimates there were 12 million new cases of syphilis in 2006. . In developing countries there is often a lack of proper screening due to limited laboratory services. In contrast, in developed countries there is often limited access to care among hard-to-reach populations. In context of these healthcare system disconnects, point-of-care (POC) tests have proven to be an invaluable resource, yet in order to justify their use, their diagnostic accuracy and implementation outcomes must first be established. Methods: We searched six electronic databases fr
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Batinovic, Lucija, and Marlon Howe. "A systematic review and meta-analysis of age discrimination in recruitment." Thesis, Linnéuniversitetet, Institutionen för psykologi (PSY), 2021. http://urn.kb.se/resolve?urn=urn:nbn:se:lnu:diva-104876.

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Correspondence and vignette experiments have already been an important part of measuring discrimination in hiring decisions for several decades, especially in terms of ethnic discrimination. Although the body of evidence is growing, no study has provided a systematic overview of age discrimination in recruitment before. Therefore, the present systematic review investigates the effect of age on discrimination levels experienced in the recruitment process, based on 14 correspondence and vignette studies in 12 distinct articles conducted between 2010 and 2019. We assess age discrimination by look
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Meyer, Nathalie. "Cervical vestibular evoked myogenic potentials : a systematic review and meta-analysis." Diss., University of Pretoria, 2014. http://hdl.handle.net/2263/46262.

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Objective: A systematic literature review and meta-analysis was performed to determine the effect of stimulus type, sternocleidomastoid (SCM) muscle activation method, transducer type and method to control SCM muscle electromyography (EMG) level on response parameter values for 0.1 ms click evoked and 500 Hz tone burst cervical vestibular evoked myogenic potentials (cVEMPs). A description of normative response values was attempted. Method: An electronic systematic literature review was performed to obtain normative cVEMP response data. Subsequently a meta-analysis was conducted to determine s
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Sena, Emily Shamiso. "Systematic review and meta-analysis of animal models of acute ischaemic stroke." Thesis, University of Edinburgh, 2010. http://hdl.handle.net/1842/4824.

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Ischaemic stroke is responsible for substantial death and disability and creates a huge financial burden for healthcare budgets worldwide. At present there are few effective treatments for acute stroke and these are urgently required. Increased understanding of the ischaemic cascade has generated interest in neuroprotection for focal cerebral ischaemia. However, treatment effects observed in of over 500 interventions in animal models have yet to be translated to the clinic. Systematic review and meta-analysis allows unbiased identification of all relevant data for a given intervention, gives a
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