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Dissertations / Theses on the topic 'Metabolic alkalosis'

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Published: 7 June 2025

Last updated: 2 August 2025

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1

Jamshaid, Abdul. "Neuroendocrine factors mediating fluid electrolyte homeostasis during chronic metabolic alkalosis in the dog." Thesis, University of Ottawa (Canada), 1986. http://hdl.handle.net/10393/4884.

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2

Hailes, Anne Maria. "The microbial degradation of the morphine alkaloids." Thesis, University of Cambridge, 1994. http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.321432.

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3

Laws, I. "Biosynthesis and metabolism of fungal indole alkaloids." Thesis, Imperial College London, 1985. http://hdl.handle.net/10044/1/37757.

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4

Wild, Stacie Lynn. "Pyrrolizidine alkaloids: Hepatic metabolism and extrahepatic toxicity." Diss., The University of Arizona, 1994. http://hdl.handle.net/10150/186599.

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Pyrrolizidine alkaloids are proposed to be metabolized in the liver to reactive pyrrole species, or dehydroalkaloids. These reactive pyrroles are hypothesized to be responsible for pyrrolizidine alkaloid toxicity. This dissertation research has established that dehydroalkaloids are, in fact, metabolites of pyrrolizidine alkaloids. It was first determined that dehydromonocrotaline is produced during hepatic microsomal metabolism of monocrotaline and that it has the ability to bind in vitro with a synthetic thiol-containing resin, Thiopropyl Sepharose 6B. Similarly, synthetic dehydromonocrotalin

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5

Hawkins, Kristy Michelle Smolke Christina D. Smolke Christina D. "Metabolic engineering of Saccharomyces cerevisiae for the production of benzylisoquinoline alkaloids /." Diss., Pasadena, Calif. : California Institute of Technology, 2009. http://resolver.caltech.edu/CaltechETD:etd-10302008-210903.

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6

Aislaitner, George. "Comparative in vitro metabolism of some tobacco alkaloids." Thesis, King's College London (University of London), 1993. http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.441208.

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7

Jones, S. V. P. "The characteristics of endplate ion channel block produced by disopyramide and two erythrina alkaloids." Thesis, University of Strathclyde, 1986. http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.372105.

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8

Sai, Yang. "Studies on the intermediary metabolism of nicotine and related alkaloids." Thesis, King's College London (University of London), 1996. http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.243508.

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9

Sachan, Nita. "Identification of signaling factors involved in the regulation of alkaloid metabolism in N.tabacum." Lexington, Ky. : [University of Kentucky Libraries], 2004. http://lib.uky.edu/ETD/ukyplph2004d00179/NS%5FDiss.pdf.

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Thesis (Ph. D.)--University of Kentucky, 2004.<br>Title from document title page (viewed Jan. 7, 2005). Document formatted into pages; contains x, 127p. : ill. Includes abstract and vita. Includes bibliographical references (p. 118-126).

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10

Liu, Xin. "In vitro and in vivo studies on the biotransformation of β-nicotyrine, a minor tobacco alkaloid". Diss., Virginia Tech, 1995. http://hdl.handle.net/10919/39263.

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β-Nicotyrine is a minor tobacco alkaloid found in both tobacco plants and tobacco smoke. Preliminary studies have shown that β-nicotyrine is pneumotoxic and that the toxicity is mediated via its metabolites formed in reactions catalyzed by cytochrome P-450. The in vitro metabolic fate of β-nicotyrine has been examined in rat liver microsomal preparations and rabbit lung and liver microsomal preparations utilizing HPLC UV-diode array analysis. Four metabolites have been identified from the incubation mixtures of β-nicotyrine with rabbit lung and liver microsomal preparations. The primary in vit

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11

Dzakovich, Michael Paul. "Exploring metabolic and genetic diversity in tomato secondary metabolites." The Ohio State University, 2020. http://rave.ohiolink.edu/etdc/view?acc_num=osu1595608017506091.

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12

Sander, Guy William. "Quantitative analysis of metabolic pathways in Catharanthus roseus hairy roots metabolically engineered for terpenoid indole alkaloid overproduction." [Ames, Iowa : Iowa State University], 2009. http://gateway.proquest.com/openurl?url_ver=Z39.88-2004&rft_val_fmt=info:ofi/fmt:kev:mtx:dissertation&res_dat=xri:pqdiss&rft_dat=xri:pqdiss:3369886.

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13

Sachan, Nita. "IDENTIFICATION OF SIGNALING FACTORS INVOLVED IN THE REGULATION OF ALKALOID METABOLISM IN N. TABACUM." UKnowledge, 2004. http://uknowledge.uky.edu/gradschool_diss/442.

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To identify the signaling mechanisms and components that are involved in regulation of a promoter for a gene involved in a secondary pathway I studied the nicotinic alkaloid biosynthetic pathway using various N. tabacum tissues. Nicotine and tropane alkaloids are widely known to be synthesized predominantly in the roots of species that produce pyrrolinium ring containing alkaloids. Putrescine Nmethyltransferase (PMT) catalyzes the first committed step in the biosynthesis of these alkaloid secondary products and earlier studies have indicated that PMT gene expression is restricted to root tissu

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14

Bapela, Mahwahwatse Johanna. "Nmr-based metabolomic study of medicinal plants used against malaria and the isolation of bioactive alkaloids." Thesis, University of Pretoria, 2016. http://hdl.handle.net/2263/53513.

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Despite the significant advances achieved in lessening the burden of malaria and other tropical diseases in recent years, protozoal infections remain a major cause of mortality in many developing countries, with malaria accounting for a large proportion of the recorded mortality. The main aim of this study was to bioprospect indigenous plant species for novel antiplasmodial plant products by means of NMRbased metabolomics. In this study, an ethnobotanical criterion was followed in collecting twenty indigenous plant species used to treat malaria or its symptoms by Vha-Venda people livin

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15

Chow, Yit Lai. "Caenorhabditis elegans as a whole organism screening system for isoquinoline alkaloid bioactivities." 京都大学 (Kyoto University), 2014. http://hdl.handle.net/2433/188834.

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16

Lamm, Katharina [Verfasser], Tobias A. M. [Akademischer Betreuer] Gulder, Tobias A. M. [Gutachter] Gulder, and Wolfgang [Gutachter] Eisenreich. "Unlocking the cryptic metabolic potential of bacterial alkaloids / Katharina Lamm ; Gutachter: Tobias A. M. Gulder, Wolfgang Eisenreich ; Betreuer: Tobias A. M. Gulder." München : Universitätsbibliothek der TU München, 2021. http://d-nb.info/1241246904/34.

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17

Kutil, Brandi Lynn. "The evolution of LOL, the secondary metabolite gene cluster for insecticidal loline alkaloids in fungal endophytes of grasses." Thesis, [College Station, Tex. : Texas A&M University, 2006. http://hdl.handle.net/1969.1/ETD-TAMU-1122.

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18

Häkkinen, Suvi T. "A functional genomics approach to the study of alkaloid biosynthesis and metabolism in Nicotiana tabacum and Hyoscyamus muticus cell cultures /." [Espoo, Finland] : VTT, 2008. http://www.vtt.fi/inf/pdf/publications/2008/P696.pdf.

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19

Weisberg, Alexandra Jamie. "Investigations into the molecular evolution of plant terpene, alkaloid, and urushiol biosynthetic enzymes." Diss., Virginia Tech, 2014. http://hdl.handle.net/10919/64408.

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Plants produce a vast number of low-molecular-weight chemicals (so called secondary or specialized metabolites) that confer a selective advantage to the plant, such as defense against herbivory or protection from changing environmental conditions. Many of these specialized metabolites are used for their medicinal properties, as lead compounds in drug discovery, or to impart our food with different tastes and scents. These chemicals are produced by various pathways of enzyme-mediated reactions in plant cells. It is suspected that enzymes in plant specialized metabolism evolved from those in pri

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20

Chintapakorn, Yupynn 1960. "An antisense approach to study the roles of arginine decarboxylase and putrescine N-methyltransferase in alkaloid metabolism in Nicotiana tabacum L." Monash University, Dept. of Biological Sciences, 2002. http://arrow.monash.edu.au/hdl/1959.1/7622.

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21

Koontz, Anne F. "EFFECTS OF ENDOPHYTE INFECTED FESCUE ALKALOID INGESTION ON ENERGY METABOLISM, NITROGEN BALANCE, IN SITU FEED DEGRADATION, AND RUMINAL PASSAGE RATES." UKnowledge, 2013. http://uknowledge.uky.edu/animalsci_etds/15.

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The decrease in productivity caused by fescue toxicosis has been estimated to cost the United States livestock industry more than $1 billion per year due to reduced growth and diminished reproductive efficiency. This goal of the research presented in this dissertation is to enhance the knowledge base concerning the underlying physiological changes that occur during fescue toxicosis that lead to reduced intake and weight gain in cattle. As one of the factors associated with fescue toxicosis is a reduction in feed intake, achieving a consistent and adequate intake of toxins can be a complication

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22

Nasomjai, Pitak. "Molecular probes for the evaluation of three isomerase enzyme mechanisms in secondary metabolism." Thesis, St Andrews, 2010. http://hdl.handle.net/10023/866.

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23

Hilliou, Frederique. "Metabolic engineering in C. roseus cell cultures : a molecular and biochemcial analysis of transgenic cell cultures carrying tdc and strI transgenes and cloning of a novel peroxidase involved in terpenoid indole alkaloid biosynthesis." Thesis, University of East Anglia, 2000. http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.301997.

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24

Dalmazo, Gabriel Ollé. "Avaliação de silenciamento gênico pós-transcricional (PTGS) de tropinona redutases em plantas de Hyoscyamus muticus L." Universidade Federal de Pelotas, 2011. http://repositorio.ufpel.edu.br/handle/ri/1322.

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Made available in DSpace on 2014-08-20T13:42:06Z (GMT). No. of bitstreams: 1 Dissertacao_Gabrie_Olle_ Dalmazo.pdf: 526235 bytes, checksum: 5e78165179f8f9e3164e0269bd617ab9 (MD5) Previous issue date: 2011-02-28<br>The tropane alkaloids (TA) pathway has a branch-point controlled by the enzymes tropinone reductase 1 and 2 (TR1 and TR2). Tropinone is the common substrate for these enzymes and is reduced either by TR1 to form tropine, hyoscyamine and scopolamine or by TR2 to form pseudotropine and calystegines. Hyoscyamine and scopolamine are largely used in medicine as anticholinergic, antieme

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25

Lengert, Adriana Hauser. "Perfil Hemogasométrico, Comportamento Ingestivo e Eficiência Alimentar de Vacas Holandês versus Mestiças Holandês- Jersey no Periparto." Universidade do Estado de Santa Catarina, 2016. http://tede.udesc.br/handle/handle/2550.

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Submitted by Claudia Rocha (claudia.rocha@udesc.br) on 2018-03-15T16:27:12Z No. of bitstreams: 1 PGCA16MA211.pdf: 910415 bytes, checksum: 51ae39dddf70a9c249c0895146f82c99 (MD5)<br>Made available in DSpace on 2018-03-15T16:27:12Z (GMT). No. of bitstreams: 1 PGCA16MA211.pdf: 910415 bytes, checksum: 51ae39dddf70a9c249c0895146f82c99 (MD5) Previous issue date: 2016-11-11<br>Capes<br>More productive and efficient animals in the feed conversion and who can dribble more stressfull transition period are critical to improving performance in intensive milk production. Crossovers arise as an alternati

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26

Foureau, Emilien. "Elucidation de la voie de biosynthèse des alcaloïdes de Catharanthus roseus et ingénierie métabolique dans la levure." Thesis, Tours, 2016. http://www.theses.fr/2016TOUR3805/document.

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Catharanthus roseus est une plante médicinale produisant divers types d’alcaloïdes indoliques monoterpéniques (AIM) d’intérêt en santé humaine. Ainsi, les AIM dimères comme la vinblastine et la vincristine sont utilisés en chimiothérapie anticancéreuse et les alcaloïdes monomères de type hétéroyohimbine présentent diverses activités pharmacologiques. La fabrication de ces molécules dans la plante est fort complexe. Elle requiert un haut niveau de compartimentation tissulaire et subcellulaire et met en jeu plus d’une trentaine d’étapes enzymatiques, dont certaines sont encore très mal connues.

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27

Galdino, Sergio Luiz. "Caracterização do metabolismo de culturas de células em suspensão de Rauvolfia sellowii Mull. Arg." Universidade de São Paulo, 2002. http://www.teses.usp.br/teses/disponiveis/46/46135/tde-20072018-181702/.

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Neste trabalho são apresentados os ensaios realizados para a caracterização da cultura de Rauvolfia sellowii Müll. Arg. (Apocynaceae). Foram determinados os parâmetros: pH, peso fresco, peso seco, produção de alcalóides, e consumo de açúcares. A curva de crescimento foi similar às observadas para as culturas de células de outras espécies, estendendo-se até o dia 14. As culturas de R. sellowii não converteram a sacarose em glicose e frutose no meio de cultura. A sacarose foi absorvida diretamente do meio. A absorção completou-se no dia 22. Não houve mudança significativa no pH do meio durante o

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28

Guirimand, Grégory. "Organisation cellulaire et subcellulaire de la voie de biosynthèse des alcaloïdes indoliques monoterpéniques de Catharantus roseus." Thesis, Tours, 2011. http://www.theses.fr/2011TOUR4014/document.

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Catharanthus roseus est une plante tropicale de la famille des Apocynacées d’intérêt thérapeutique en raison de sa capacité à synthétiser des alcaloïdes indoliques monoterpéniques (AIM) utilisés en chimiothérapie anticancéreuse. La teneur en AIM in planta est très faible notamment en raison d’une haute compartimentalisation cellulaire et subcellulaire de la voie de biosynthèse. Si la compartimentalisation cellulaire était bien caractérisée, très peu de données de localisation subcellulaire in situ étaient disponibles au début de cette thèse. Une connaissance fine de cette compartimentalisation

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29

Meyer, Golo M. J. Verfasser], and Hans H. [Akademischer Betreuer] [Maurer. "Herbal drugs of abuse Glaucium flavum and Sceletium tortuosum : metabolism and toxicological detectability of their alkaloids glaucine, mesembrine and mesembrenone studied in rat urine and human liver preparations using GC-MS, LC-MS, LC-HR-MSn, and NMR / Golo M. J. Meyer. Betreuer: Hans H. Maurer." Saarbrücken : Saarländische Universitäts- und Landesbibliothek, 2014. http://d-nb.info/1064305768/34.

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30

Philipp, Anika-Anina Verfasser], and Hans H. [Akademischer Betreuer] [Maurer. "Studies on the phase I and II metabolism and the toxicological analysis of the alkaloids of the herbal drug of abuse Mitragyna speciosa Korth. (Kratom) using gas chromatography-mass spectrometry and liquid chromatography coupled to low- and high-resolution linear ion trap mass spectrometry / Anika-Anina Philipp. Betreuer: Hans H. Maurer." Saarbrücken : Saarländische Universitäts- und Landesbibliothek, 2011. http://d-nb.info/1051284848/34.

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31

Ginis, Olivia. "Identification de facteurs de transcription régulateurs de la voie de biosynthèse des alcaloïdes indoliques monoterpéniques chez Catharanthus roseus." Thesis, Tours, 2012. http://www.theses.fr/2012TOUR4014/document.

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Catharanthus roseus est une plante tropicale qui produit spécifiquement des alcaloïdes indoliques monoterpéniques (AIM) d’intérêt thérapeutique. Chez C. roseus, la branche terpénique incluant la voie du méthylérythritol phosphate (MEP) est considérée comme limitante et présente une régulation transcriptionnelle coordonnée en réponse aux hormones inductrices de l’accumulation alcaloïdique. Lors de ce travail, suite à des analyses bioinformatiques et à la caractérisation de promoteurs de gènes de la voie MEP, nous avons identifié de nouvelles familles de facteurs de transcription impliquées dans

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32

Chung, Woon-Gye. "Comparative metabolism of the pyrrolizidine alkaloid senecionine in rat and guinea pig." Thesis, 1993. http://hdl.handle.net/1957/35327.

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33

"The biological activities of narciclasine." 2002. http://library.cuhk.edu.hk/record=b5891153.

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Wong Chi-Fai.<br>Thesis (M.Phil.)--Chinese University of Hong Kong, 2002.<br>Includes bibliographical references (leaves 119-132).<br>Abstracts in English and Chinese.<br>Abstract --- p.i<br>Acknowledgements --- p.iv<br>List of Abbreviations --- p.v<br>List of Figures --- p.vii<br>List of Tables --- p.ix<br>Chapter 1 --- Introduction<br>Chapter 1.1 --- Plant secondary metabolites --- p.1<br>Chapter 1.2 --- Plant alkaloids --- p.6<br>Chapter 1.3 --- Narciclasine --- p.12<br>Chapter 1.3.1 --- Isoquinoline alkaloids --- p.12<br>Chapter 1.3.2 --- Amaryllidaceae alkaloids --- p.14<br>Chap

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34

Hovermale, Jeannette Talbot. "Metabolism of pyrrolizidine alkaloids by ruminal microbes." Thesis, 1998. http://hdl.handle.net/1957/36743.

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35

Hawkins, Kristy Michelle. "Metabolic Engineering of Saccharomyces cerevisiae for the Production of Bensylisoquinoline Alkaloids." Thesis, 2009. https://thesis.library.caltech.edu/4335/1/ChapterI.pdf.

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<p>The engineering of synthetic metabolic pathways in microbial hosts holds much promise for the synthesis of new chemicals and materials, including a variety of natural and non-natural products. The benzylisoquinoline alkaloids (BIAs) represent a large and structurally diverse class of plant secondary metabolites that exhibit a broad range of pharmacological activities. The reconstitution of a BIA biosynthetic pathway in an engineered microbial host offers several advantages over isolation from plants, including the targeted production of key intermediate molecules, rapid biomass accumulation

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36

"In vitro metabolism of clivorine, a hepatotoxic otonecine-type pyrrolizidine alkaloid." 1999. http://library.cuhk.edu.hk/record=b6073138.

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by Cui Yanyan.<br>"June 1999."<br>Thesis (Ph.D.)--Chinese University of Hong Kong, 1999.<br>Includes bibliographical references (p. 154-163).<br>Electronic reproduction. Hong Kong : Chinese University of Hong Kong, [2012] System requirements: Adobe Acrobat Reader. Available via World Wide Web.<br>Mode of access: World Wide Web.<br>Abstracts in English and Chinese.

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37

Ayers, Andrea Wilson. "Ruminal metabolism and transport of tall fescue ergot alkaloids." 2003. http://purl.galileo.usg.edu/uga%5Fetd/ayers%5Fandrea%5Fw%5F200312%5Fms.

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38

Duringer, Jennifer Marie. "Metabolism of toxic plant alkaloids in livestock : comparative studies on the hepatic metabolism of pyrrolizidine alkaloids in sheep and cattle and of ergot alkaloids in an endophyte-resistant mouse model." Thesis, 2003. http://hdl.handle.net/1957/31167.

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The pyrrolizidine alkaloids (PAs) and ergot alkaloids are known natural toxicants found in livestock forage. These alkaloids contribute to large economic losses in livestock throughout the world. An understanding of the mechanisms of toxicity and development of better diagnostic tools for better management practices was investigated. Variability exists in the toxicity of PAs in ruminants where cattle are more susceptible and sheep are more resistant. The mechanism of PA resistance in sheep has been attributed to hepatic metabolism or rumen microbial degradation of PAs to non-toxic moieties. Th

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39

Peebles, Christie A. M. "Metabolic engineering of the terpenoid indole alkaloid pathway of Catharanthus roseus hairy roots." Thesis, 2008. http://hdl.handle.net/1911/22161.

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Catharanthus roseus is an important medicinal plant that produces a number of bioactive terpenoid indole alkaloids (TIAs). Specifically, vinblastine and vincristine and their semi-synthetic derivatives are important anticancer drugs used clinically. Low product yields have propelled researchers to pursue ways to increase TIA biosynthesis. Our group pursues this objective by developing tools to aid in the metabolic engineering of C. roseus hairy roots and by applying these tools to the study of pathway genes and regulators. Within this thesis, the long-term genetic and biochemical stability of

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40

Faber, Johan Henrik. "Naphthylisoquinoline Alkaloids : Structural Elucidation, Metabolism and Functional Analysis of their Bioactivities." Doctoral thesis, 2007. https://nbn-resolving.org/urn:nbn:de:bvb:20-opus-22789.

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This thesis deals with the isolation and structural elucidation of bioactive naphthylisoquinoline alkaloids and related analogs. The mode of action of the antiplasmodial activity exhibited by the naphthylisoquinoline alkaloids was explored and compared to that of the antimalarial drug chloroquine. Furthermore, the phase 1 and 2 metabolism of dioncophyllines A and C and dioncopeltine A were investigated. In detail the following results have been obtained: • From the leaves of the recently discovered East African liana A. tanzaniensis six naphthylisoquinoline alkaloids were isolated. • The leave

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41

Veselá, Tereza. "Vliv biologické ochrany rostlin na produkci sekundárních metabolitů Papaver somniferum IV." Master's thesis, 2018. http://www.nusl.cz/ntk/nusl-387760.

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Vesela T.: Influence of plant biological control on production of secondary metabolites of Papaver somniferum IV. Diploma thesis, Charles University, Faculty of Pharmacy in Hradec Kralove, Department of pharmaceutical botany, Hradec Kralove 2018. In the experimental part of the thesis was studied the influence of plant biological control on the production of the main pharmaceutically usable secondary metabolites of opium poppy (Papaver somniferum L.). The contents of alkaloids morphine, codeine, thebain, papaverine and narcotine were monitored in the capsules and stems. Two poppy varieties, Or

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42

Cheng, Yachih, and 鄭雅之. "Effect of alkaloids from fermentated vinegar and meivinegar on uric acid metabolism , antioxidant andantimutagenicity." Thesis, 2004. http://ndltd.ncl.edu.tw/handle/25386966765036861387.

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碩士<br>中山醫學大學<br>營養科學研究所<br>92<br>Alkaline foods are good for health. Most of alkaline foods are vegetable products. Fermented vinegar is also one kind of them, which could keep blood pH in normal range and some other benefits. However, studys about the healthy protection of alkaline foods are still deficient. In order to understand the healthy protection of fermentated vinegar and mei, fermentated vinegar and mei vinegar were used in this study. In addition to compare with their alkalinity, contents of metal ions and alkaloids levels, their function on xanthine oxidase（XO）inhibition, antioxid

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43

Urbanová, Lucie. "Produkce sekundárních metabolitů v explantátových kulturách Trichocereus pachanoi (Cactaceae)." Master's thesis, 2016. http://www.nusl.cz/ntk/nusl-348995.

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Production of secondary metabolites in the explant cultures of Trichocereus pachanoi (Cactaceae) Lucie Urbanová Diploma thesis Charles University in Prague, Faculty of Pharmacy in Hradec Králové, Pharmacy Key words: Trichocereus pachanoi, the explant cultures, mescaline, secondary metabolites, prodrugs, elicitation, cinnamic acid, sodium cinnamate, tryptophan, ozone, methylene blue The aim of this thesis was the research of effect of selected precursors and elicitors for secondary metabolite production of mescaline in explant cultures Trichocereus pachanoi. Suspension cultures were cultivated

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44

Jílek, Lukáš. "Biologická aktivita sekundárních metabolitů rostlin II. Alkaloidy Narcissus jonquilla L." Master's thesis, 2015. http://www.nusl.cz/ntk/nusl-379183.

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Jílek L.: The biological activity of secondary plants metabolites II. Alkaloids of Narcissus jonquilla L. Charles University in Prague, Faculty of Pharmacy in Hradec Králové, Department of Pharmaceutical Botany and Ecology, Hradec Králové 2015, pp. 74. The aim of the diploma thesis was a preparation of alkaloid extracts to identification of alkaloid patterns and measure cholinesterase inhibitory activity. This activity is useful for treating Alzheimer's disease. Alkaloid extracts of seven Narcissus jonquilla L. (Amaryllidaceae) varieties (Bella Estrella, Bell Song, Fruit Cup, Hill Star, Chit C

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45

Nováková, Dana. "Biologická aktivita sekundárních metabolitů rostlin I. Alkaloidy Narcissus jonquilla L." Master's thesis, 2015. http://www.nusl.cz/ntk/nusl-331210.

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Nováková D.: Biological activity of secondary plants metabolites I. Alkaloids of Narcissus jonquilla L. Charles University in Prague, Faculty of Pharmacy in Hradec Králové, Department of Pharmaceutical Botany and Ecology, Hradec Králové 2015, pp. 70. The aim of the diploma thesis was a preparation of alkaloid extracts to identification of alkaloid patterns and measure cholinesterase inhibitory activity. This activity is useful for treating Alzheimer's disease. Alkaloid extracts of seven Narcissus jonquilla L. (Amaryllidaceae) varieties (Sundial, Sundisc, Sweetness, Waterperry, Simplex, Twinkli

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46

Panchartková, Markéta. "Biologická aktivita sekundárních metabolitů rostlin III. Alkaloidy Narcissus tazetta L." Master's thesis, 2015. http://www.nusl.cz/ntk/nusl-331236.

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Panchartková, M.: Biological aktivity of secondary plants metabolites III. Alkaloids of Narcissus tazetta L., Diploma thesis, Charles University in Prague, Faculty of Pharmacy in Hradec Králové, Department of Pharmaceutical Botany and Ecology, Hradec Králové, 2015, 67s. Plants from the Amaryllidaceae family contain alkaloids that have multiple biological effects. There is described antiviral, antitumor, antibacterial, antimalarial and anti-fungal effect. Activity against human cholinesterases is important too. The aim of this thesis was to prepare seven alkaloid extracts of individual cultivar

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Carqueijeiro, Marta Inês Soares Teto. "Unraveling the metabolism and transmembrane transport of the highly valuable medicinal alkaloids from Catharanthus roseus." Doctoral thesis, 2013. https://repositorio-aberto.up.pt/handle/10216/68178.

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Carqueijeiro, Marta Inês Soares Teto. "Unraveling the metabolism and transmembrane transport of the highly valuable medicinal alkaloids from Catharanthus roseus." Tese, 2013. https://repositorio-aberto.up.pt/handle/10216/68178.

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Bouz, Lukáš. "Biologická aktivita sekundárních metabolitů rostlin V. Alkaloidy Vinca minor L." Master's thesis, 2016. http://www.nusl.cz/ntk/nusl-344091.

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Bouz L.: Biological activity of secondary plants metabolites V. Alkaloids of Vinca minor L. Diploma thesis, Charles University, Faculty of Pharmacy in Hradec Králové, Department of Pharmaceutical Botany and Ecology, Hradec Králové 2016. Summary extract obtained from dried aerial parts of Vinca minor L. was separated by column chromatography with petrol, chloroform and ethanol to 531 fractions. By further separation of fractions, following preparative thin layer chromatography and crystallization 2 alkaloidal compounds marked LB-2 and LB-3 were isolated. These compounds were identified by GC/MS

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Vítovcová, Aneta. "Biologická aktivita sekundárních metabolitů rostlin IV. Alkaloidy Vinca minor L." Master's thesis, 2016. http://www.nusl.cz/ntk/nusl-347048.

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Vítovcová, A.: Biological activity of secondary plants metabolites IV. Alkaloids of Vinca minor L. Diploma thesis, Charles University in Prague, Faculty of Pharmacy in Hradec Králové, Department of Pharmaceutical Botany and Ecology, Hradec Králové 2016. Extract of Vinca minor L. was separated to fractions in column chromatography. Flash chromatography, preparative TLC and crystalisation led to isolation of two alkaloids from fraction number two and number five. Alkaloids were identified by GC/MS as (+)-vincaminorine and vincorine. These alkaloids were tested for their inhibition activity towar

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