Academic literature on the topic 'Metabolic architecture'

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Journal articles on the topic "Metabolic architecture"

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Dollens, Dennis, and AnneMarie Maes. "Dialectics of Nature: Metabolic Architectures Meet Intelligent Guerrilla Beehives." Leonardo 53, no. 5 (October 2020): 563–70. http://dx.doi.org/10.1162/leon_a_01770.

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Between realms of cellular life, city occupation and technology, AnneMarie Maes's Intelligent Guerrilla Beehive project and Dennis Dollens's metabolic architectures share a theoretical lineage and form-finding curiosity, subscribing to the view that species' intelligence and their built environments can contribute to experimental art and architecture. Microbe, plant, animal and machine intelligences then root our research considering bees, microbes and computational simulation as participants in generative design and technological communication, AI and community. The article discusses sculptural, architectural and theoretical logic/design as it draws from nature to hybridize types of intelligences spanning matter, phenomena and life.
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Uehara, Minoru. "Metabolic Computing." International Journal of Distributed Systems and Technologies 3, no. 3 (July 2012): 27–39. http://dx.doi.org/10.4018/jdst.2012070103.

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In this paper, the author proposes a metabolic computing model for a truly renewable system with high fault tolerance and sustainability and a realistic architecture for the model using four kinds of elements: metaboloids, slots, a power queue, and recycle unit. Metaboloids, which are processing units, are arranged in a mesh in the power queue. However, as the metabolism may change the network, to manage running tasks, metaboloids must achieve homeostasis, for which two new algorithms, bubbling and drifting, are presented. For simple metabolism, the specification of the architecture does not change. Consequently, despite using innovative hardware manufacturing technologies, performance does not improve. The author proposes an evolutional architecture for a metabolic computing model, whereby a set of metaboloids with different specifications can work together if the specification is portable and the difference between specifications is at most 1. Finally, the author presents a reflective architecture for the power queue, minimizing the number of unrenewable units.
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Rontein, Denis, Martine Dieuaide-Noubhani, Erick J. Dufourc, Philippe Raymond, and Dominique Rolin. "The Metabolic Architecture of Plant Cells." Journal of Biological Chemistry 277, no. 46 (September 10, 2002): 43948–60. http://dx.doi.org/10.1074/jbc.m206366200.

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Velez, Daniel O., Sural K. Ranamukhaarachchi, Aditya Kumar, Rishi N. Modi, Esther W. Lim, Adam J. Engler, Christian M. Metallo, and Stephanie I. Fraley. "3D collagen architecture regulates cell adhesion through degradability, thereby controlling metabolic and oxidative stress." Integrative Biology 11, no. 5 (May 1, 2019): 221–34. http://dx.doi.org/10.1093/intbio/zyz019.

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AbstractThe collagen-rich tumor microenvironment plays a critical role in directing the migration behavior of cancer cells. 3D collagen architectures with small pores have been shown to confine cells and induce aggressive collective migration, irrespective of matrix stiffness and density. However, it remains unclear how cells sense collagen architecture and transduce this information to initiate collective migration. Here, we tune collagen architecture and analyze its effect on four core cell-ECM interactions: cytoskeletal polymerization, adhesion, contractility, and matrix degradation. From this comprehensive analysis, we deduce that matrix architecture initially modulates cancer cell adhesion strength, and that this results from architecture-induced changes to matrix degradability. That is, architectures with smaller pores are less degradable, and degradability is required for cancer cell adhesion to 3D fibrilar collagen. The biochemical consequences of this 3D low-attachment state are similar to those induced by suspension culture, including metabolic and oxidative stress. One distinction from suspension culture is the induction of collagen catabolism that occurs in 3D low-attachment conditions. Cells also upregulate Snail1 and Notch signaling in response to 3D low-attachment, which suggests a mechanism for the emergence of collective behaviors.
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Scott, Nadia A., and Timothy H. Murphy. "Glial Laminar Cortical Architecture Matches Metabolic Demand." Journal of Cerebral Blood Flow & Metabolism 31, no. 3 (December 8, 2010): 793–94. http://dx.doi.org/10.1038/jcbfm.2010.205.

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Baranwal, Mayank, Abram Magner, Paolo Elvati, Jacob Saldinger, Angela Violi, and Alfred O. Hero. "A deep learning architecture for metabolic pathway prediction." Bioinformatics 36, no. 8 (December 26, 2019): 2547–53. http://dx.doi.org/10.1093/bioinformatics/btz954.

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Abstract Motivation Understanding the mechanisms and structural mappings between molecules and pathway classes are critical for design of reaction predictors for synthesizing new molecules. This article studies the problem of prediction of classes of metabolic pathways (series of chemical reactions occurring within a cell) in which a given biochemical compound participates. We apply a hybrid machine learning approach consisting of graph convolutional networks used to extract molecular shape features as input to a random forest classifier. In contrast to previously applied machine learning methods for this problem, our framework automatically extracts relevant shape features directly from input SMILES representations, which are atom-bond specifications of chemical structures composing the molecules. Results Our method is capable of correctly predicting the respective metabolic pathway class of 95.16% of tested compounds, whereas competing methods only achieve an accuracy of 84.92% or less. Furthermore, our framework extends to the task of classification of compounds having mixed membership in multiple pathway classes. Our prediction accuracy for this multi-label task is 97.61%. We analyze the relative importance of various global physicochemical features to the pathway class prediction problem and show that simple linear/logistic regression models can predict the values of these global features from the shape features extracted using our framework. Availability and implementation https://github.com/baranwa2/MetabolicPathwayPrediction. Supplementary information Supplementary data are available at Bioinformatics online.
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Riehl, William J., Paul L. Krapivsky, Sidney Redner, and Daniel Segrè. "Signatures of Arithmetic Simplicity in Metabolic Network Architecture." PLoS Computational Biology 6, no. 4 (April 1, 2010): e1000725. http://dx.doi.org/10.1371/journal.pcbi.1000725.

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Satoh-Nagasawa, Namiko, Nobuhiro Nagasawa, Simon Malcomber, Hajime Sakai, and David Jackson. "A trehalose metabolic enzyme controls inflorescence architecture in maize." Nature 441, no. 7090 (May 2006): 227–30. http://dx.doi.org/10.1038/nature04725.

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Seda, Ondrej, Frantisek Liska, Drahomira Krenova, Ludmila Kazdova, Lucie Sedova, Tomas Zima, Junzheng Peng, et al. "Dynamic genetic architecture of metabolic syndrome attributes in the rat." Physiological Genomics 21, no. 2 (April 14, 2005): 243–52. http://dx.doi.org/10.1152/physiolgenomics.00230.2004.

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The polydactylous rat strain (PD/Cub) is a highly inbred (F > 90) genetic model of metabolic syndrome. The aim of this study was to analyze the genetic architecture of the metabolic derangements found in the PD/Cub strain and to assess its dynamics in time and in response to diet and medication. We derived a PD/Cub × BN/Cub (Brown Norway) F2 intercross population of 149 male rats and performed metabolic profiling and genotyping and multiple levels of genetic linkage and statistical analyses at five different stages of ontogenesis and after high-sucrose diet feeding and dexamethasone administration challenges. The interval mapping analysis of 83 metabolic and morphometric traits revealed over 50 regions genomewide with significant or suggestive linkage to one or more of the traits in the segregating PD/Cub × BN/Cub population. The multiple interval mapping showed that, in addition to “single” quantitative train loci, there are more than 30 pairs of loci across the whole genome significantly influencing the variation of particular traits in an epistatic fashion. This study represents the first whole genome analysis of metabolic syndrome in the PD/Cub model and reveals several new loci previously not connected to the genetics of insulin resistance and dyslipidemia. In addition, it attempts to present the concept of “dynamic genetic architecture” of metabolic syndrome attributes, evidenced by shifts in the genetic determination of syndrome features during ontogenesis and during adaptation to the dietary and pharmacological influences.
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Gauthier, Marion, Romain Barillot, Anne Schneider, Camille Chambon, Christian Fournier, Christophe Pradal, Corinne Robert, and Bruno Andrieu. "A functional structural model of grass development based on metabolic regulation and coordination rules." Journal of Experimental Botany 71, no. 18 (June 4, 2020): 5454–68. http://dx.doi.org/10.1093/jxb/eraa276.

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Abstract Shoot architecture is a key component of the interactions between plants and their environment. We present a novel model of grass, which fully integrates shoot morphogenesis and the metabolism of carbon (C) and nitrogen (N) at organ scale, within a three-dimensional representation of plant architecture. Plant morphogenesis is seen as a self-regulated system driven by two main mechanisms. First, the rate of organ extension and the establishment of architectural traits are regulated by concentrations of C and N metabolites in the growth zones and the temperature. Second, the timing of extension is regulated by rules coordinating successive phytomers instead of a thermal time schedule. Local concentrations are calculated from a model of C and N metabolism at organ scale. The three-dimensional representation allows the accurate calculation of light and temperature distribution within the architecture. The model was calibrated for wheat (Triticum aestivum) and evaluated for early vegetative stages. This approach allowed the simulation of realistic patterns of leaf dimensions, extension dynamics, and organ mass and composition. The model simulated, as emergent properties, plant and agronomic traits. Metabolic activities of growing leaves were investigated in relation to whole-plant functioning and environmental conditions. The current model is an important step towards a better understanding of the plasticity of plant phenotype in different environments.
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Dissertations / Theses on the topic "Metabolic architecture"

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Vemuri, Bhargav R. "Identification of prognostic metabolic classifier in localized clear cell renal cell carcinoma." University of Cincinnati / OhioLINK, 2020. http://rave.ohiolink.edu/etdc/view?acc_num=ucin161710619577556.

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Zaworski, Julie. "Deinococcus geothermalis genome scale structure study to design and engineer heterologous metabolic pathways." Thesis, Université Paris-Saclay (ComUE), 2017. http://www.theses.fr/2017SACLE031.

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Deinococcus geothermalis est un organisme non-model intéressant pour les bio-productions de part sa résistance extrême et ses capacités de fermentation partant de diverses sources de carbone. Cependant les outils d’ingénierie permettant une fine maîtrise des voix métaboliques restent limités pour cet organisme. Le but de ce travail de thèse, est d’essayer de surpasser cet obstacle à travers l’observation des motifs génétiques et de leur organisation. L’analyses de ces motifs a été menée via deux approches. La première est l’étude de l’impact de la position dans le génome sur l’expression d’une cassette reportrice. Grâce à une collection de 150 souches, nous avons observé que l’expression est plus forte au niveau de l’origine de réplication que du terminus. Une autre observation concerne la présence de zone de forte expression réparties symétriquement le long du chromosome. La seconde approche est l’analyse des motifs génétiques en cas de stress grace outil GREAT:SCAN:patterns. Ces motifs sont fortement liés régulation de l’expression des gènes et sont des points intéressant pour l’ingénierie du génome. En analysant les résultats de différentes conditions de stress ainsi que les régulons décrits dans la littérature, nous avons pu observer que des stress voisins partagent les mêmes motifs et que ces motifs semblent conservés chez des organismes distants. Ces deux approches ont permis de déterminer des positions d’insertion dans le génome intéressantes pour l’ingénierie métabolique
Deinococcus geothermalis is a non-model organism of high interest for bio-manufacturing since it shows a extreme resistance and good capacities for fermentation process on different carbon sources. However the engineering tools are limited to finely tuned metabolic pathways for bio-productions. This PhD work aims at contributing to overcome this obstacle through a whole-genome approach to the issue of understanding the genomic organization of D. geothermalis and defined interesting genomic locations. The whole-genome approach is based on the existence of genome-scale patterns that were analyzed in two different ways. A first approach consisted of studying the influence of the genome location on the expression of a reporter cassette. On a library of over 150 strains, the expression is higher near the origin of replication than near the terminus, a common observation. However, other hot spots of expression along the genome additionally appeared with a symmetric distribution about the origin of replication. The second approach consisted of analyzing the genomic patterns under stress through the in-house GREAT:SCAN:patterns software. These patterns interrelate with gene expression regulation and are an interesting key for genome engineering. Testing different stress conditions and considering the matching regulons as described in the literature, it appeared that related stresses share genomic patterns. Moreover these patterns tend to be conserved between distant organisms. These two approaches lead to define interesting genome loci for inserting genes encoding the enzymes of a pathway, with a view to metabolic engineering
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Oswal, Vipul Kantilal. "Pathway Pioneer: Heterogenous Server Architecture for Scientific Visualization and Pathway Search in Metabolic Network Using Informed Search." DigitalCommons@USU, 2014. https://digitalcommons.usu.edu/etd/2775.

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There is a huge demand for analysis and visualization of the biological models. PathwayPioneer is a web-based tool to analyze and visually represent complex biological models. PathwayPioneer generates the initial layout of the model and allows users to customize it. It is developed using .net technologies (C#) and hosted on the Internet Information Service (IIS) server. At back-end it interacts with python-based COBRApy library for biological calculations like Flux Balance Analysis (FBA). We have developed a parallel processing architecture to accommodate processing of large models and enable message-based communication between the .net webserver and python engine. We compared the performance of our online system by loading a website with multiple concurrent dummy users and performed different time intensive operations in parallel. Given two metabolites of interest, millions of pathways can be found between them even in a small metabolic network. Depth First Search or Breadth First search algorithm retrieves all the possible pathways, thereby requiring huge computational time and resources. In Pathway Search using Informed Method, we have implemented, compared, and analyzed three different informed search techniques (Selected Subsystem, Selected Compartment, and Dynamic Search) and traditional exhaustive search technique. We found that the Dynamic approach performs exceedingly well with respect to time and total number of pathways searches. During our implementation we developed a SBML parser which outperforms the commercial libSBML parser in C#.
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Athanassiadis, Aristide. "Towards more comprehensive urban environmental assessments: Exploring the complex relationship between urban and metabolic profiles." Doctoral thesis, Universite Libre de Bruxelles, 2016. https://dipot.ulb.ac.be/dspace/bitstream/2013/232139/5/contrataa.pdf.

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Urban areas cover 2% of the Earth’s land surface, host more than 50% of global population and are estimated to account for around 75% of CO2 emissions from global energy use. In order to mitigate existing and future direct and indirect environmental pressures resulting from urban resource use, it is necessary to investigate and better understand resource and pollution flows associated with urban systems.Current urban environmental assessment methodologies enable the quantification of resource use and pollution emissions flows entering, becoming stocked and exiting urban areas. While these methodologies enable to estimate the environmental effect of cities, they often consider urban areas as being static and homogeneous systems. This partial and simplistic representation shadows the complex spatio-temporal interrelationships between the local context and its associated local and global environmental pressures. This characterisation of urban systems is a significant limitation, not only for the urban environmental assessments, but also for the identification of their drivers as it may lead to inadequate urban environmental policies. To overcome this limitation and effectively reduce glocal urban environmental pressures, it is necessary to better understand the complex functioning of cities and identify their drivers.This research developed a comprehensive urban environmental assessment framework that helps to better explicit and understand the complex relationship between an urban system and its environmental profile in a systemic and systematic way. This framework was applied to the case study of Brussels Capital Region (BCR).Results from the application of this framework show that urban systems are neither static nor homogeneous. In fact, different relationships between the urban and metabolic profiles appear when considering different spatial scales and temporal intervals as well as different urban and metabolic metrics. The establishment of BCR’s urban profile showed that components that shape the urban system evolve in an organic way over time. Moreover, the spatial expression of an urban system portrays its heterogeneous aspect and how different metrics of the same urban indicator can reveal distinct facets and challenges for an urban area or a neighbourhood. Finally, it was demonstrated that the relationship between urban indicators is different for each spatial scale and therefore knowledge from one spatial scale is not necessarily transferable from one scale to another. The establishment and analysis of BCR’s metabolic profile also underlined the complex functioning of cities as each flow has a different temporal evolution and spatial expression. Due to the multifaceted and intertwined aspect of metabolic flows it becomes clear that no single parameter enables to explain or predict their behaviour. This leads to the conclusion that a great number of questions still need to be considered, understood and answered before effectively and coherently reducing environmental pressures from cities. The developed framework proposes a number of concrete steps that enable existing and new cities to better understand their metabolic functioning and ultimately transition towards less environmentally harmful futures.
Doctorat en Art de bâtir et urbanisme (Polytechnique)
info:eu-repo/semantics/nonPublished
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Heshmati, Elnaz. "A Modular Shared Home : Approaching affordable housing through sharing habits and modularity." Thesis, Umeå universitet, Arkitekthögskolan vid Umeå universitet, 2020. http://urn.kb.se/resolve?urn=urn:nbn:se:umu:diva-173531.

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The world’s population is increasing and every day, more people are coming to the cities. People are constantly relocating their houses for meeting their needs. As societies are growing and mobility in cities is raising, cities would face challenges like accommodating the population inexpensively and providing good quality of life and stable social and environmental infrastructure for them. However, due to the fixed regulated and unadaptable construction market, the architecture doesn’t meet the changing needs of inhabitants, therefore, every day the housing market is more unaffordable because of the high demand for housing developments, lands scarce, etc. Architecture needs to be flexible to adjust itself to the current market. Since most of the relocations and high demands for building new housing projects occur when built spaces fail to meet their occupants’ growing needs. This thesis tries to find an alternative framework for designing a flexible one whereby architecture is shaped by the user’s needs and can adjust itself in a long period. This thesis also works on designing an environment that responds to the social, economic, and environmental needs of residents as one united community. Therefore, it uses a shared living idea as an affordable alternative for making houses cheaper and creating a more stable social environment for inhabitants. The content of this thesis is categorized upon the following narrative. Firstly, this thesis is trying to deepen its understanding of the matter of shared living and its possible advantages and disadvantages for producing stable social and economical infrastructure. For this purpose, it analyses a notion of shared living and shared economy through studying successful case studies. Secondly, by studying and utilizing metabolic design criteria, the thesis will form an understanding of a more sustainable approach toward architecture and built environment to design an affordable housing system that provides high quality of life for inhabitants through responding to their needs. Thirdly, the thesis will frame its design strategy based on shared living perspective and metabolic design criteria. The thesis then will illustrate its steps and methods to achieve flexible architecture through designing its module, structure, and material. Lastly, it will discuss its findings on how the shared living approach and metabolic philosophy can aid architects to design more sustainable housing units that can meet their resident’s needs through a long period and make strong social, economic, and environmental infrastructure.
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Vince, Tommy. "Fluid Built: Becoming 0001 : A world where the object adapts plurally to its subjects, not the contrary." Thesis, Umeå universitet, Arkitekthögskolan vid Umeå universitet, 2018. http://urn.kb.se/resolve?urn=urn:nbn:se:umu:diva-148460.

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Gluck, Thaler Emile. "Computational, Evolutionary and Functional Genetic Characterization of Fungal Gene Clusters Adapted to Degrade Plant Defense Chemicals." The Ohio State University, 2019. http://rave.ohiolink.edu/etdc/view?acc_num=osu1555406081422532.

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Gerbaix, Maude. "Interventions nutritionnelles, exercice physique et perturbations métaboliques : réponses micro-architecturales, densitométrique, biomécaniques et cellulaires du tissu osseux chez le rat mâle. Induction de l'obésité et prise en charge." Thesis, Clermont-Ferrand 2, 2012. http://www.theses.fr/2012CLF20061.

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Si l’obésité a longtemps été considérée comme protectrice pour le squelette, sa prise en charge nutritionnelle s’accompagne d’une perte osseuse. Dans le but d’étudier les mécanismes liant le tissu adipeux et le tissu osseux, des rats ont été nourris avec un régime riche en graisse et en sucre afin d’induire une obésité et ses complications métaboliques. Puis, ces rats ont suivi un programme de prise en charge de l’obésité associant un rééquilibrage nutritionnel à de l’activité physique. Des investigations de la densité, de la micro architecture trabéculaire, de la qualité corticale, des propriétés biomécaniques et des paramètres cellulaires du tissu osseux ont été réalisées sur le squelette des rats. L’obésité induite a amélioré les paramètres densitométriques et corticaux des rats. La prise en charge de l’obésité a entraîné des effets contrastés. Le rééquilibrage de l’alimentation n’a pas altéré la densité ni les paramètres biomécaniques et corticaux du tissu osseux des rats en dépit d’altérations de la micro architecture et des perturbations l’activité cellulaire osseuse. L’exercice a augmenté la densité minérale osseuse du tibia des rats. Nos résultats montrent que l’inclusion de l’exercice dans un programme de prise en charge de l’obésité permet de potentialiser la perte de masse grasse et de maintenir l’intégrité du squelette. En étudiant l’impact d’un régime obésogène et de la prise en charge de l’obésité sur le tissu osseux chez le rat, ce travail de thèse apporte sa contribution dans la compréhension des mécanismes liant le tissu adipeux et le tissu osseux
While obesity has long been considered protective of bone tissue, its nutritional management is linked to a concomitant bone loss. In order to access these mechanisms, male rats were given a high fat / high sucrose diet to induce obesity and its resulting metabolic disorders. Then, these rats participated in a well balanced nutritional program combined, or not, with physical activity in order to treat their obesity. Investigations on density, trabecular micro-architecture, cortical quality, biomechanical properties and cellular parameters of bone tissue were performed on rat’s skeleton. Obesity had improved the bone density and cortical parameters of rats. Obesity management had induced mixed effects. The well balanced diet did alter neither the bone density nor biomechanical and cortical parameters despite the presence of alterations in the trabecular micro architecture and some disturbances of bone cellular activity. Exercise by itself had increased the tibia bone mineral density. Our results show that including exercise in obesity management allows increasing the fat mass loss and maintaining the skeleton integrity. By studying the impact of an obesogenic diet and obesity treatment on bone tissue in rats, this study brings its contribution to the understanding of the mechanisms linking adipose tissue and bone tissue
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Oktem, Caner. "Urban Archipelago reconsidered : a new metabolism in Tokyo Bay for contemporary coastal urbanism." Thesis, Massachusetts Institute of Technology, 2016. http://hdl.handle.net/1721.1/106422.

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Thesis: S.M., Massachusetts Institute of Technology, Department of Architecture, 2016.
Cataloged from PDF version of thesis.
Includes bibliographical references (pages 133-145).
Coastal areas are home to more than half of the world's population and many of its most populated urban areas. Coastal urbanism remains very much in demand despite major risk factors such as sea level rise, longterm shoreline erosion, storm surges, land liquefaction, and subsidence. City-building on reclaimed land is an ambitious form of development yet prevalent around the world, especially where an economic growth agenda is pursued aggressively against the availability of land resources. This thesis develops a critical design agenda to respond to how pro-growth forces and environmental change can be negotiated towards a reconsidered coastal urbanism. The thesis argument is that coastal urban and territorial form should not follow a static master plan based on a risk model; instead, it should employ/follow a dynamic gradient of permanence and ephemerality in multiple time scales, following coastal succession as a design analogy. Tokyo Bay is the site of experimentation. The world's largest metropolitan area has a long history of land reclamation debates and projects, which resulted in a highly articulated urban coast with reclaimed shorelines, and near- and off-shore artificial islands with a mix of uses. The on-going construction of the urban archipelago is an outcome of urban and regional metabolisms, where incinerated solid waste, dredged sediment, excavated soil, and demolished buildings are deposited to make new land. Demand for post-industrial urban development and land reclamation is still alive in coastal Tokyo despite the vulnerabilities of flooding and seismic events. Large waterfront sites are now available for new development. The construction of permanent and temporary facilities in Tokyo Bay for the 2020 Summer Olympics offers an opportunity to develop a succession- based design strategy-not only for the 2020 peak condition, but also in anticipation of future transformations. The design exploration establishes, via strategic cartography, a resiliency district framework based on a gradient of permanence and flexibility in the ground condition. The sharply delineated boundary between land and sea is rethought as a dynamic frontier zone of flexibility that adapts to flooding and sea level rise and as an active site for coastal deposition and submersion. A second, elevated ground level is proposed to serve as a pedestrian and emergency thoroughfare, as well as an extension of transportation and logistics infrastructure. The Metabolist imaginary envisioned Tokyo Bay as a site of continuous urban growth towards a mega-scale climax state; ground was taken for granted and the possibilities of urban decline or reconstruction were hardly considered within the same design utopia. This project argues for a New Metabolism in which the ground is conceived as an indeterminate landscape of change. The uncertainties of the ground are addressed by an 'artificial land' infrastructure which organizes and facilitates transformation over time.
by Caner Oktem.
S.M.
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Pretorius, Lloyd. "Suburban metabolism a project for a suburb of the future." Master's thesis, University of Cape Town, 2012. http://hdl.handle.net/11427/5588.

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One of my initial research questions was to answer how informal settlements can pioneer the mitigation of greenhouse gas emissions in Cape Town. The objectives included understanding energy usage in informal settlements, invetigating current energy technologies and innovating an architectural typology which can support multiple renewable fuel sources and create positive, urban space in these communities.
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Books on the topic "Metabolic architecture"

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Mildred Lane Kemper Art Museum, ed. Metabolic city. St. Louis, Mo: Mildred Lane Kemper Art Museum, Washington University, 2009.

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Ovádi, Judit. Cell architecture and metabolite channeling. New York: Springer-Verlag, 1995.

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Ovádi, Judit. Cell architecture and metabolite channeling. Austin: R.G. Landes Co., 1995.

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Kishō, Kurokawa. Kisho Kurokawa: From metabolism to symbiosis. London: Academy Editions, 1992.

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Kurokawa, Kisho. From metabolism to symbiosis. London: Adademy Editions/St. Martin's Press, 1992.

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Kenzo Tange and the Metabolist movement: Urban utopias of modern Japan. New York: Routledge, 2010.

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Kurokawa, Kisho. Kisho Kurokawa: The architecture of symbiosis. New York: Rizzoli, 1988.

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1964-, Cachola Schmal Peter, Flagge Ingeborg, Visscher Jochen, and Deutsches Architekturmuseum, eds. Kisho Kurokawa: Metabolism and symbiosis = Metabolismus und Symbiosis. Berlin: Jovis, 2005.

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Kisho Kurokawa: The architecture of symbiosis. New York: Rizzoli, 1988.

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Guiheux, A. Kisho Kurokawa, architecte: Le Métabolisme 1960-1975. Paris: Centre Georges Pompidou, 1997.

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Book chapters on the topic "Metabolic architecture"

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Saavedra, Francisco, Ekaterina Boyarchuk, Francisca Alvarez, Geneviève Almouzni, and Alejandra Loyola. "Metabolic Deregulations Affecting Chromatin Architecture: One-Carbon Metabolism and Krebs Cycle Impact Histone Methylation." In RNA Technologies, 573–606. Cham: Springer International Publishing, 2019. http://dx.doi.org/10.1007/978-3-030-14792-1_23.

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Fischer, Verena, and Simon Hickinbotham. "A Metabolic Subsumption Architecture for Cooperative Control of the e-Puck." In Nature Inspired Cooperative Strategies for Optimization (NICSO 2010), 1–12. Berlin, Heidelberg: Springer Berlin Heidelberg, 2010. http://dx.doi.org/10.1007/978-3-642-12538-6_1.

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Gómez Canaval, Sandra, José Ramón Sánchez, and Fernando Arroyo. "Simulating Metabolic Processes Using an Architecture Based on Networks of Bio-inspired Processors." In Unconventional Computation and Natural Computation, 255–56. Berlin, Heidelberg: Springer Berlin Heidelberg, 2013. http://dx.doi.org/10.1007/978-3-642-39074-6_28.

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Abraham, Wolf-Rainer. "Protocols for Microcosms for Growing Biofilms on Hydrophobic Substrates: A Polyphasic Approach to Study Biodiversity, Metabolic Activity, and Biofilm Architecture." In Springer Protocols Handbooks, 111–33. Berlin, Heidelberg: Springer Berlin Heidelberg, 2014. http://dx.doi.org/10.1007/8623_2014_35.

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Singh, Ishwar, Krishan Kumar, Prabha Singh, Pranjal Yadava, and Sujay Rakshit. "Physiological and molecular interventions for improving nitrogen-use efficiency in maize." In Molecular breeding in wheat, maize and sorghum: strategies for improving abiotic stress tolerance and yield, 325–39. Wallingford: CABI, 2021. http://dx.doi.org/10.1079/9781789245431.0019.

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Abstract This chapter discusses (i) the importance of nitrogen in plant growth and development, (ii) what is nitrogen-use efficiency (NUE) and how to manage it, (iii) traits influencing nitrogen-uptake efficiency including root system architecture, root nitrogen transporter system, and interaction with microorganisms, (iv) traits influencing nitrogen-utilization efficiency, such as nitrate assimilation, canopy photosynthesis per unit of nitrogen, (v) identification and use of quantitative trait loci (QTLs) related to NUE, (vi) identification of nitrogen-responsive genes, and (vii) nitrogen signalling and transduction for improving NUE. Intensive research on molecular and genetic aspects of NUE has led to the identification of many new genes, QTLs and alleles that could be deployed to develop new genotypes. The future direction of the research efforts should be towards understanding the interaction of NUE-related genes with cellular small RNA flux and perturbing the system performance through metabolic engineering and genome editing techniques.
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Ovádi, Judit, and Vic Norris. "Moonlighting Function of the Tubulin Cytoskeleton: Macromolecular Architectures in the Cytoplasm." In Systems Biology of Metabolic and Signaling Networks, 165–78. Berlin, Heidelberg: Springer Berlin Heidelberg, 2013. http://dx.doi.org/10.1007/978-3-642-38505-6_7.

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Huang, Yiran, Cheng Zhong, Jinxiong Zhang, Ye Li, and Jun Liu. "Parallel Aligning Multiple Metabolic Pathways on Hybrid CPU and GPU Architectures." In Communications in Computer and Information Science, 483–92. Singapore: Springer Singapore, 2017. http://dx.doi.org/10.1007/978-981-10-6442-5_46.

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Tepfer, David, Jean-Pierre Damon, Gozal Ben-Hayyim, Alessandro Pellegrineschi, Daniel Burtin, and Josette Martin-Tanguy. "Control of Root System Architecture through Chemical and Genetic Alterations of Polyamine Metabolism." In Biology of Adventitious Root Formation, 181–89. Boston, MA: Springer US, 1994. http://dx.doi.org/10.1007/978-1-4757-9492-2_14.

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Ruiz-May, Eliel, and Jocelyn K. C. Rose. "Cell Wall Architecture and Metabolism in Ripening Fruit and the Complex Relationship with Softening." In The Molecular Biology and Biochemistry of Fruit Ripening, 163–87. Oxford, UK: Blackwell Publishing Ltd., 2013. http://dx.doi.org/10.1002/9781118593714.ch7.

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"Metabolic systems." In Built to Grow – Blending architecture and biology, 126–33. Birkhäuser, 2016. http://dx.doi.org/10.1515/9783035607475-011.

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Conference papers on the topic "Metabolic architecture"

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Uehara, Minoru. "Proposal of an Evolutional Architecture for Metabolic Computing." In 2011 Third International Conference on Intelligent Networking and Collaborative Systems (INCoS). IEEE, 2011. http://dx.doi.org/10.1109/incos.2011.138.

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Motyka, Vaclav. "ROOTING IN ARTEMISIA ALBA TURRA AS A MODELLING CLUE IN CHLOROPLAST ARCHITECTURE AND CYTOKININ METABOLIC CONJUGATION IN VITRO." In 19th SGEM International Multidisciplinary Scientific GeoConference EXPO Proceedings. STEF92 Technology, 2019. http://dx.doi.org/10.5593/sgem2019v/6.3/s08.026.

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Rejniak, Katarzyna A., Sharan Poonja, Shreya Mathur, Jessica Kingsley, and Marilyn Bui. "Abstract LT017: ECM mechanical and metabolic architecture during early ductal invasions: integrating in silico modeling, histology-based machine learning and mechanobiology." In Abstracts: AACR Virtual Special Conference: The Evolving Tumor Microenvironment in Cancer Progression: Mechanisms and Emerging Therapeutic Opportunities; in association with the Tumor Microenvironment (TME) Working Group; January 11-12, 2021. American Association for Cancer Research, 2021. http://dx.doi.org/10.1158/1538-7445.tme21-lt017.

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Vishwasrao, Harshad. "Two-Photon Fluorescence Imaging and Spectroscopy of NADH in Brain Tissue: New Insights into the Intra- and Intercellular Metabolic Architecture of the Brain." In Frontiers in Optics. Washington, D.C.: OSA, 2005. http://dx.doi.org/10.1364/fio.2005.jmb3.

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Berringer, Molly A., Paige J. Boehmcke, Jason Z. Fischman, Athena Y. Huang, Youngjun Joh, J. Cali Warner, V. N. Murthy Arelekatti, Matthew J. Major, and Amos G. Winter. "Modular Design of a Passive, Low-Cost Prosthetic Knee Mechanism to Enable Able-Bodied Kinematics for Users With Transfemoral Amputation." In ASME 2017 International Design Engineering Technical Conferences and Computers and Information in Engineering Conference. American Society of Mechanical Engineers, 2017. http://dx.doi.org/10.1115/detc2017-68278.

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There is a significant need for low-cost, high-performance prosthetic knee technology for transfemoral amputees in India. Replicating able-bodied gait in amputees is biomechanically necessary to reduce the metabolic cost, and it is equally important to mitigate the socio-economic discrimination faced by amputees in developing countries due to their conspicuous gait deviations. This paper improves upon a previous study of a fully passive knee mechanism, addressing the issues identified in its user testing in India. This paper presents the design, analysis and bench-level testing of the three major functional modules of the new prosthetic knee architecture: (i) a four-bar latch mechanism for achieving stability during stance phase of walking, (ii) an early stance flexion module designed by implementing a fully adjustable mechanism, and (iii) a hydraulic rotary damping system for achieving smooth and reliable swing-phase control.
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Foged, I. W. "Architectural metabolic forms." In DESIGN AND NATURE 2012. Southampton, UK: WIT Press, 2012. http://dx.doi.org/10.2495/dn120101.

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Wu, Yongren, John Glaser, and Hai Yao. "Effects of Endplate and Mechanical Loading on Solute Transport in Intervertebral Disc." In ASME 2008 Summer Bioengineering Conference. American Society of Mechanical Engineers, 2008. http://dx.doi.org/10.1115/sbc2008-193111.

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The intervertebral disc (IVD) is the largest cartilaginous structure in human body that contributes to flexibility and load support in the spine. To accomplish these functions, the disc has a unique architecture consisting of a centrally-located nucleus pulposus (NP) surrounded superiorly and inferiorly by cartilage endplates (CEP) and peripherally by the annulus fibrosus (AF). Disc degeneration is strongly linked to low back pain. Poor nutrient supply has been suggested as a potential mechanism for disc degeneration. Previous theoretical studies have shown that the distributions of nutrients and metabolites (e.g., oxygen, glucose, and lactate) within the IVD depended on tissue diffusivities, nutrient supply, and cellular metabolic rates [1, 2]. Based on a multiphasic mechano-electrochemical finite element model of human IVD [3], our recent theoretical study suggested that the mechanical loading has little effect on small solute transport (e.g., glucose), but significantly affects large solute transport (e.g., growth factor). The objective of this study was to further develop the multiphasic finite element model of IVD by including the cartilage endplate and considering the nutrient consumption of disc cells. Using this model, the effects of endplate and mechanical loading on solute transport in IVD were examined.
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BOREL, Jean-Christian, Renaud TAMISIER, Jésus GONZALEZ-BARMEJO, Denis MONNERET, Nathalie ARNOL, Pascale ROUX-LOMBARD, Patrick A. Levy, and Jean-Louis PEPIN. "One-month Of Non-Invasive Ventilation In Obesity Hypoventilation Syndrome Improves Sleep Architecture And Blood Gazes But Has No Impact On Inflammatory, Metabolic And Cardiovascular Status: A Randomized Controlled Trial." In American Thoracic Society 2010 International Conference, May 14-19, 2010 • New Orleans. American Thoracic Society, 2010. http://dx.doi.org/10.1164/ajrccm-conference.2010.181.1_meetingabstracts.a5576.

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D’Amore, Antonio, John A. Stella, William R. Wagner, and Michael S. Sacks. "A Method to Extract the Complete Fiber Network Topology of Planar Fibrous Tissues and Scaffolds." In ASME 2010 Summer Bioengineering Conference. American Society of Mechanical Engineers, 2010. http://dx.doi.org/10.1115/sbc2010-19166.

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Improving fabrication protocols and design strategies, investigating on how fibrous ECM and synthetic architectures affect cell morphology, metabolism and phenotypic expression, predicting mechanical behaviors, have increasingly become crucial goals in the understanding of native tissues and in the development of engineered tissue. In the present study, an image-based analysis approach that provides an automatic tool to fully characterize engineered tissue fiber network topology was developed. The following micro architectural features were detected: fiber angle distribution, fiber connectivity, fiber overlap spatial density, and fiber diameter. In order to demonstrate the potential of this approach Electrospun poly(ester urethane)urea (ES-PEUU) scaffolds were studied. Electrospun scaffolds were chosen for their recognized capability to recapitulate native soft tissue extra cellular matrix (ECM) morphology.
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"System Dynamics for Modeling Metabolism Mechanisms for Urban Planning." In 2018 Symposium on Simulation for Architecture and Urban Design. Society for Modeling and Simulation International (SCS), 2018. http://dx.doi.org/10.22360/simaud.2018.simaud.030.

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