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1

Karimova, Maksuda Ahmedjanovna, and Dilnoza Kakhramanovna Kurbanbaeva. "Problems Of Metabolic Syndrome." American Journal of Medical Sciences and Pharmaceutical Research 03, no. 06 (2021): 52–55. http://dx.doi.org/10.37547/tajmspr/volume03issue06-08.

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At the beginning of the third millennium, for mankind, which overcame the epidemic of life-threatening infections during its centuries-old history, the problem of cardiovascular diseases (CVD) came to the fore in relevance among all causes of morbidity and mortality. A significant role in this was played by lifestyle modification associated with limiting physical activity, increasing the calorie content of food, and a steady increase in emotional stress. All of this potentiates the main risk factors for CVD, which are a “negative asset of progress,” namely increased blood pressure (BP), dyslip
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2

Hjermann, Ingvar. "The Metabolic Cardiovascular Syndrome." Journal of Cardiovascular Pharmacology 20, Supplement 8 (1992): S5—S10. http://dx.doi.org/10.1097/00005344-199220008-00002.

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3

Jain, Vikas, S. K. Dwivedi, and R. K. Sharma. "Association of Metabolic Syndrome Parameters with Exercise Capacity and Cardiovascular Parameters." International Physiology 6, no. 2 (2018): 148–55. http://dx.doi.org/10.21088/ip.2347.1506.6218.20.

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4

Citrome, Leslie. "Metabolic Syndrome and Cardiovascular Disease." Journal of Psychopharmacology 19, no. 6_suppl (2005): 84–93. http://dx.doi.org/10.1177/0269881105058375.

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Metabolic syndrome is a constellation of clinical findings that identify individuals at higher than normal risk of developing diabetes mellitus or cardiovascular disease. There are two principal definitions, one emerging from the American National Cholesterol Education Program Expert Panel on Detection, Evaluation, and Treatment of High Blood Cholesterol in Adults, and the other from the World Health Organization. Both definitions share the common elements of abdominal obesity, hypertriglyceridaemia, low HDL-cholesterol, hypertension and abnormal glucose regulation. The syndrome is relatively
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5

Cha, Bong Soo, and Hae Jin Kim. "Metabolic Syndrome and Cardiovascular Disease." Korean Circulation Journal 33, no. 8 (2003): 645. http://dx.doi.org/10.4070/kcj.2003.33.8.645.

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6

Rocha, Evangelista. "Metabolic syndrome and cardiovascular risk." Revista Portuguesa de Cardiologia (English Edition) 38, no. 5 (2019): 333–35. http://dx.doi.org/10.1016/j.repce.2019.06.006.

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7

Tune, Johnathan D., Adam G. Goodwill, Daniel J. Sassoon, and Kieren J. Mather. "Cardiovascular consequences of metabolic syndrome." Translational Research 183 (May 2017): 57–70. http://dx.doi.org/10.1016/j.trsl.2017.01.001.

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8

Krentz, Andrew J., Nathan D. Wong, Andrew J. Krent, and Nathan D. Wong. "METABOLIC SYNDROME AND CARDIOVASCULAR DISEASE." Shock 27, no. 5 (2007): 591. http://dx.doi.org/10.1097/01.shk.0000258381.48362.80.

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9

Rocha, Evangelista. "Metabolic syndrome and cardiovascular risk." Revista Portuguesa de Cardiologia 38, no. 5 (2019): 333–35. http://dx.doi.org/10.1016/j.repc.2019.06.003.

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10

Arnesen, Harald. "Introduction: The Metabolic Cardiovascular Syndrome." Journal of Cardiovascular Pharmacology 20, Supplement 8 (1992): S1—S4. http://dx.doi.org/10.1097/00005344-199200208-00001.

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11

Alshehri, AbdullahM. "Metabolic syndrome and cardiovascular risk." Journal of Family and Community Medicine 17, no. 2 (2010): 73. http://dx.doi.org/10.4103/1319-1683.71987.

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12

Sorrentino, Matthew J. "Metabolic Syndrome and Cardiovascular Disease." Medicine & Science in Sports & Exercise 39, no. 6 (2007): 1027. http://dx.doi.org/10.1249/mss.0b013e318074e839.

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13

Qiao, Qing, Weiguo Gao, Lei Zhang, Regzedmaa Nyamdorj, and Jaakko Tuomilehto. "Metabolic syndrome and cardiovascular disease." Annals of Clinical Biochemistry 44, no. 3 (2007): 232–63. http://dx.doi.org/10.1258/000456307780480963.

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14

Siddiqui, M. Shadab, and Richard K. Sterling. "Posttransplant Metabolic Syndrome." International Journal of Hepatology 2012 (2012): 1–6. http://dx.doi.org/10.1155/2012/891516.

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Metabolic syndrome (MS) is a cluster of metabolic derangements associated with insulin resistance and an increased risk of cardiovascular mortality. MS has become a major health concern worldwide and is considered to be the etiology of the current epidemic of diabetes and cardiovascular disease. In addition to cardiovascular disease, the presence of MS is also closely associated with other comorbidities including nonalcoholic fatty liver disease (NAFLD). The prevalence of MS in patients with cirrhosis and end-stage liver disease is not well established and difficult to ascertain. Following liv
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15

Adnan, Muhammad, Tayyaba Rahat, Naheed Hashmat, and Zahra Ali. "METABOLIC SYNDROME;." Professional Medical Journal 24, no. 04 (2017): 539–44. http://dx.doi.org/10.29309/tpmj/2017.24.04.1442.

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Background: Metabolic syndrome and diabetes mellitus are the modifiable riskfactors of cardiovascular diseases that double the chance of illness when occur together. Littlework has been reported on the superlative criteria to diagnose metabolic syndrome amongdiabetics from the country. Therefore, the study was aimed to find the agreement betweenmetabolic syndrome diagnostic criteria among type 2 diabetics. Methods: The retrospectivedata of 373 known type 2 diabetics who had reported history of taking antidiabetic medicineswas analyzed. The new International Diabetes Federation definition, the
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16

BEJAN, Gabriel Cristian, Liviu Nicolae GHILENCEA, Mihaela Adela IANCU, Mihaela Daniela BALTĂ, and Dumitru MATEI. "The impact of modern cardiovascular risk factors associated with metabolic syndrome on long-term outcome." Romanian Journal of Medical Practice 10, no. 4 (2015): 380–87. http://dx.doi.org/10.37897/rjmp.2015.4.12.

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Metabolic syndrome is also called insulin resistance syndrome or catecholamine excess syndrome and is a cluster of cardiometabolic factors that result in increased incidence of cardiovascular disease and diabetes type 2. Due to sedentary lifestyle and hypercaloric diet with an increased content of saturated fat and carbohydrates that characterizes modern life style of the population, especially in urban areas, the prevalence of metabolic syndrome is increasing, thus becoming a very topical issue for the medical world. During the years 2013-2014 we conducted an observational study on a sample o
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17

McNamara, Anthony. "Metabolic syndrome." InnovAiT: Education and inspiration for general practice 12, no. 10 (2019): 582–88. http://dx.doi.org/10.1177/1755738019864615.

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Metabolic syndrome is the name given to a combination of cardiovascular risk factors. These include hyperinsulinaemia, impaired glucose tolerance, hypertension, central obesity and dyslipidaemia. People with metabolic syndrome have a high risk of developing type 2 diabetes, non-alcoholic fatty liver disease, and vascular conditions including coronary artery disease, peripheral vascular disease, and stroke. Central obesity can predispose to sleep apnoea and restrictive lung disease. For many years, it has been taught that the underlying mechanism of metabolic syndrome is insulin resistance seco
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18

Hu, Gang, Qing Qiao, and Jaakko Tuomilehto. "The Metabolic Syndrome and Cardiovascular Risk." Current Diabetes Reviews 1, no. 2 (2005): 137–43. http://dx.doi.org/10.2174/1573399054022820.

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19

Huang, Paul L. "eNOS, metabolic syndrome and cardiovascular disease." Trends in Endocrinology & Metabolism 20, no. 6 (2009): 295–302. http://dx.doi.org/10.1016/j.tem.2009.03.005.

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20

Shimamoto, Kazuaki. "2. Metabolic Syndrome and Cardiovascular Disease." Nihon Naika Gakkai Zasshi 97, no. 3 (2008): 591–97. http://dx.doi.org/10.2169/naika.97.591.

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21

Rutter, Martin K., James B. Meigs, and Peter W. F. Wilson. "Cardiovascular Risk and the Metabolic Syndrome." Metabolic Syndrome and Related Disorders 4, no. 4 (2006): 252–60. http://dx.doi.org/10.1089/met.2006.4.252.

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22

Tremblay, Angelo. "Physical activity and metabolic cardiovascular syndrome." British Journal of Nutrition 80, no. 3 (1998): 215–16. http://dx.doi.org/10.1017/s000711459800124x.

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23

Altinbas, Kursat, Filiz Alkan, Serhat Tuni, and Sema Yesilyurt. "Metabolic syndrome related cardiovascular disease risk." International Clinical Psychopharmacology 26 (September 2011): e40-e41. http://dx.doi.org/10.1097/01.yic.0000405699.60866.b7.

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24

Os, Ingrid, and Gudmund Nordby. "Hypertension and the Metabolic Cardiovascular Syndrome." Journal of Cardiovascular Pharmacology 20, Supplement 8 (1992): S15—S21. http://dx.doi.org/10.1097/00005344-199220008-00004.

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25

Hjelmesæth, Jøran, Anders Hartmann, Karsten Midtvedt, et al. "Metabolic cardiovascular syndrome after renal transplantation." Nephrology Dialysis Transplantation 16, no. 5 (2001): 1047–52. http://dx.doi.org/10.1093/ndt/16.5.1047.

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26

Aggoun, Yacine. "Obesity, Metabolic Syndrome, and Cardiovascular Disease." Pediatric Research 61, no. 6 (2007): 653–59. http://dx.doi.org/10.1203/pdr.0b013e31805d8a8c.

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27

Bonora, Enzo. "The metabolic syndrome and cardiovascular disease." Annals of Medicine 38, no. 1 (2006): 64–80. http://dx.doi.org/10.1080/07853890500401234.

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28

Grundy, Scott M. "Obesity, Metabolic Syndrome, and Cardiovascular Disease." Journal of Clinical Endocrinology & Metabolism 89, no. 6 (2004): 2595–600. http://dx.doi.org/10.1210/jc.2004-0372.

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29

Nestel, Paul. "Metabolic syndrome: the new cardiovascular target." Current Opinion in Lipidology 15, no. 1 (2004): 1–3. http://dx.doi.org/10.1097/00041433-200402000-00002.

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30

Mottillo, Salvatore, Kristian B. Filion, Jacques Genest, et al. "The Metabolic Syndrome and Cardiovascular Risk." Journal of the American College of Cardiology 56, no. 14 (2010): 1113–32. http://dx.doi.org/10.1016/j.jacc.2010.05.034.

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31

Tzimas, Petros, and Haralampos Milionis. "Metabolic Syndrome." Angiology 68, no. 4 (2016): 304–5. http://dx.doi.org/10.1177/0003319716669461.

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32

Golomb, Beatrice A. "Metabolic Syndrome." Journal of the American College of Cardiology 53, no. 24 (2009): 2280–82. http://dx.doi.org/10.1016/j.jacc.2009.03.029.

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33

Denke, Margo A. "Metabolic syndrome." Current Atherosclerosis Reports 4, no. 6 (2002): 444–47. http://dx.doi.org/10.1007/s11883-002-0048-9.

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34

Caglayan, Evren, Florian Blaschke, Yasunori Takata, and Willa A. Hsueh. "Metabolic syndrome-interdependence of the cardiovascular and metabolic pathways." Current Opinion in Pharmacology 5, no. 2 (2005): 135–42. http://dx.doi.org/10.1016/j.coph.2005.01.008.

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35

Cheng, Tsung O. "The metabolic syndrome, formerly called metabolic “Syndrome X”." American Journal of Cardiology 94, no. 1 (2004): 148–49. http://dx.doi.org/10.1016/j.amjcard.2004.03.019.

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36

Pivonello, Rosario, Antongiulio Faggiano, Gaetano Lombardi, and Annamaria Colao. "The Metabolic Syndrome and Cardiovascular Risk in Cushing's Syndrome." Endocrinology and Metabolism Clinics of North America 34, no. 2 (2005): 327–39. http://dx.doi.org/10.1016/j.ecl.2005.01.010.

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37

Dandona, Paresh, Ahmad Aljada, Ajay Chaudhuri, Priya Mohanty, and Rajesh Garg. "Metabolic Syndrome." Circulation 111, no. 11 (2005): 1448–54. http://dx.doi.org/10.1161/01.cir.0000158483.13093.9d.

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38

BEJAN, Gabriel Cristian, Dumitru MATEI, and Adela IANCU. "Prevalence of metabolic syndrome within hypertensive population and the risk of developing atherosclerotic cardiovascular diseases." Romanian Journal of Medical Practice 10, no. 2 (2015): 187–94. http://dx.doi.org/10.37897/rjmp.2015.2.17.

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Metabolic syndrome, also called insulin resistance syndrome or excess of catecholamines, is represented by several cardiometabolic factors that result in increased incidence of cardiovascular disease and type 2 diabetes. Due to sedentary lifestyle and hypercaloric food, with a high percent of saturated fats and carbohydrates, that characterize modern lifestyle of the population, especially in urban areas, the prevalence of metabolic syndrome recorded an ascending slope that makes it a very topical issue for the medical world. During the years 2013-2014 we conducted an observational study on a
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39

de la Sierra, Alejandro. "The Clinical Significance of Metabolic Syndrome in Hypertension: Metabolic Syndrome Increases Cardiovascular Risk." High Blood Pressure & Cardiovascular Prevention 15, no. 2 (2008): 53–57. http://dx.doi.org/10.2165/00151642-200815020-00003.

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40

Sarzani, Riccardo. "The Clinical Significance of Metabolic Syndrome in Hypertension: Metabolic Syndrome Increases Cardiovascular Risk." High Blood Pressure & Cardiovascular Prevention 15, no. 2 (2008): 59–62. http://dx.doi.org/10.2165/00151642-200815020-00004.

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41

Okamoto, Yoshihisa. "Adiponectin Provides Cardiovascular Protection in Metabolic Syndrome." Cardiology Research and Practice 2011 (2011): 1–7. http://dx.doi.org/10.4061/2011/313179.

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Adipose tissue plays a central role in the pathogenesis of metabolic syndrome. Adiponectin (APN) is a bioactive adipocytokine secreted from adipocytes. Low plasma APN levels (hypoadiponectinemia) are observed among obese individuals and in those with related disorders such as diabetes, hypertension, and dyslipidemia. APN ameliorates such disorders. Hypoadiponectinemia is also associated with major cardiovascular diseases including atherosclerosis and cardiac hypertrophy. Accumulating evidence indicates that APN directly interacts with cardiovascular tissue and prevents cardiovascular pathology
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42

Hjermann, Ingvar. "The Metabolic Cardiovascular Syndrome: Syndrome X, Reavenʼs Syndrome, Insulin Resistance Syndrome, Atherothrombogenic Syndrome". Journal of Cardiovascular Pharmacology 20, Supplement 8 (1992): S5—S10. http://dx.doi.org/10.1097/00005344-199200208-00002.

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43

Montecucco, Fabrizio, Luca Liberale, and Federico Carbone. "Novel cardiovascular risk biomarkers in metabolic syndrome." Biomarkers in Medicine 13, no. 16 (2019): 1331–34. http://dx.doi.org/10.2217/bmm-2019-0366.

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44

Zhou, Ji-Yin, Lawrence Chan, and Shi-Wen Zhou. "Omentin: Linking Metabolic Syndrome and Cardiovascular Disease." Current Vascular Pharmacology 12, no. 1 (2014): 136–43. http://dx.doi.org/10.2174/1570161112999140217095038.

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45

Nesto, Richard W. "Managing cardiovascular risk inpatients with metabolic syndrome." Clinical Cornerstone 7, no. 2-3 (2005): 46–51. http://dx.doi.org/10.1016/s1098-3597(05)80067-5.

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46

Grundy, Scott M. "Metabolic Syndrome: A Multiplex Cardiovascular Risk Factor." Journal of Clinical Endocrinology & Metabolism 92, no. 2 (2007): 399–404. http://dx.doi.org/10.1210/jc.2006-0513.

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47

Kawada, Tomoyuki. "Smoking, hyperhomocysteinemia, metabolic syndrome, and cardiovascular risk." Nutrition 81 (January 2021): 111031. http://dx.doi.org/10.1016/j.nut.2020.111031.

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48

Blomhoff, Jan P. "Lipoproteins, Lipases, and the Metabolic Cardiovascular Syndrome." Journal of Cardiovascular Pharmacology 20, Supplement 8 (1992): S22—S25. http://dx.doi.org/10.1097/00005344-199200208-00005.

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49

Westheim, Arne, and Ingrid Os. "Physical Activity and the Metabolic Cardiovascular Syndrome." Journal of Cardiovascular Pharmacology 20, Supplement 8 (1992): S49—S53. http://dx.doi.org/10.1097/00005344-199200208-00010.

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50

Blomhoff, Jan P. "Lipoproteins, Lipases, and the Metabolic Cardiovascular Syndrome." Journal of Cardiovascular Pharmacology 20, Supplement 8 (1992): S22—S25. http://dx.doi.org/10.1097/00005344-199220008-00005.

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