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Relevant bibliographies by topics / Metabolic P system

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Academic literature on the topic 'Metabolic P system'

Author: Grafiati

Published: 11 March 2023

Last updated: 31 July 2025

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Journal articles on the topic "Metabolic P system"

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Kulakovskis, Darius, and Dalius Navakauskas. "Automated Metabolic P System Placement in FPGA." Electrical, Control and Communication Engineering 10, no. 1 (2016): 5–12. http://dx.doi.org/10.1515/ecce-2016-0001.

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Abstract An original Very High Speed Integrated Circuit Hardware Description Language (VHDL) code generation tool that can be used to automate Metabolic P (MP) system implementation in hardware such as Field Programmable Gate Arrays (FPGA) is described. Unlike P systems, MP systems use a single membrane in their computations. Nevertheless, there are many biological processes that have been successfully modeled by MP systems in software. This is the first attempt to analyze MP system hardware implementations. Two different MP systems are investigated with the purpose of verifying the developed

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Kulakovskis, Darius. "APPLICATION PROSPECTS OF METABOLIC P SYSTEM / METABOLINĖS P SISTEMOS TAIKYMO GALIMYBĖS." Mokslas – Lietuvos ateitis 7, no. 3 (2015): 285–90. http://dx.doi.org/10.3846/mla.2015.784.

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Metabolic P (MP) systems are a class of P systems and are based on metabolic process which is used by living organisms. We review for the purpose of experimental research the MP system development, implementation and modeling. To implement MP systems in dedicated hardware, some specifications need to be determined. We look into the possibility of modeling MP systems in fixed point arithmetic capable hardware and determine the minimal needed bit count for selected MP system model. A way to improve the accuracy of fixed point calculations is proposed, which includes the modification of MP gramma

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Manca, Vincenzo, Roberto Pagliarini, and Simone Zorzan. "A photosynthetic process modelled by a metabolic P system." Natural Computing 8, no. 4 (2008): 847–64. http://dx.doi.org/10.1007/s11047-008-9104-x.

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Pagliarini, Roberto, Giuditta Franco, and Vincenzo Manca. "An Algorithm for Initial Fluxes of Metabolic P Systems." International Journal of Computers Communications & Control 4, no. 3 (2009): 263. http://dx.doi.org/10.15837/ijccc.2009.3.2434.

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A central issue in systems biology is the study of efficient methods inferring fluxes of biological reactions by starting from experimental data. Among the different techniques proposed in the last years, the theory of Metabolic P systems, which is based on the Log-Gain principle, proved to be helpful for deducing biologi- cal fluxes from temporal series of observed dynamics. According to this approach, the algebraic systems provided by the Log-Gain principle determine the reaction fluxes underlying a system dynamics when initial fluxes are known. Here we propose a heuristic algorithm for esti

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Melanson, Edward L., Patty S. Freedson, Devra Hendelman, and Edward Debold. "Reliability and Validity of a Portable Metabolic Measurement System." Canadian Journal of Applied Physiology 21, no. 2 (1996): 109–19. http://dx.doi.org/10.1139/h96-010.

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The purpose of this study was to assess the reliability and validity of a portable metabolic system (TEEM 100) during submaximal and maximal [Formula: see text] exercise using a computer-based metabolic system as the reference system (REF). Between repeated trials of submaximal exercise at three constant loads, differences in ventilation [Formula: see text] and oxygen consumption [Formula: see text] were 0.2 ± 4.9 L∙min−1 and 0.03 ± 0.10 L∙min−1 for REF, and 1.9 ± 0.7 L∙min−1 and 0.00 ± 0.17 L∙min−1 for TEEM 100. Pooled intraclass reliability coefficients for [Formula: see text] and [Formula:

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Singh, Arushi, Poonam Mani, Shashi Prateek, Lalita Yadav, and Eshna Gupta. "Impact of levonorgestrel intrauterine system on metabolic parameters." International Journal of Reproduction, Contraception, Obstetrics and Gynecology 8, no. 3 (2019): 830. http://dx.doi.org/10.18203/2320-1770.ijrcog20190433.

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Background: Hormonal contraceptive is suggested to affect parameters like body mass index, body weight, blood pressure (BP), blood sugar, lipid protein, and liver function test (LFT) but effect of LNG-IUS on those parameters is still uncertain. The aim of the present study was to study the effects of LNG-IUS on the metabolic parameters.Methods: Sixty women who opted for LNG-IUS for various indications were included in the study. Lipid profile, liver function tests (LFT), glucose levels [fasting and post prandial (PP)], and hemoglobin (Hb) were tested. Bimanual genital examination and transvagi

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Becker, Wolfgang, Lukas Braun, Rodrigo Suarez-Ibarrol, and Arkadiusz Miernik. "Metabolic Imaging by Simultaneous FLIM of NAD(P)H and FAD." Current Directions in Biomedical Engineering 6, no. 3 (2020): 254–56. http://dx.doi.org/10.1515/cdbme-2020-3064.

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AbstractWe describe a metabolic imaging system based on simultaneous recording of lifetime images of NAD(P)H and FAD. The system uses one-photon excitation by ps diode lasers, scanning by galvanometer mirrors, confocal detection, and two parallel TCSPC FLIM recording channels. Two lasers, with wavelengths of 375nm and 410 nm, are multiplexed to alternatingly excite NAD(P)H and FAD. One FLIM channel detects in the emission band of NAD(P)H, the other in the emission band of FAD. For both channels, the data analysis delivers images of the amplitudes of the decay components, a1 and a2. We show tha

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Pogadayev, Daniil Vladimirovich, Larisa Аnatoliyevna Miniaylo, and Svetlana Viktorovna Gridneva. "ASSESSMENT OF OXIDATIVE METABOLIC SYSTEM PARAMETERS AFTER CORRECTION WITH THE FLAVONOID DIHYDROQUERCETIN." Scientific medical Bulletin of Ugra 32, no. 2 (2022): 181–83. http://dx.doi.org/10.25017/2306-1367-2022-32-2-181-183.

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A total of 71 residents, living for more than 10 years in the Khanty-Mansiysk Autonomous Region with poor-quality water treatment and not employed in the manufacturing sector, were examined: 29 (40,8%) men and 42 (59,2%) women, average age 38,3 ± 8,9 years. The indicators of POL above the reference values, and AOZ – below the physiologically optimal values were established. After receiving for metabolic correction antioxidant drug dihydroquercetin for a month there was a statistically significant decrease in primary (GPl, p=0.025) and secondary (TBA-AP, p=0,049) of LPO products, significant 1,

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Urbutis, Mingaudas, Dovilė Malašauskienė, Mindaugas Televičius, Vida Juozaitienė, Walter Baumgartner, and Ramūnas Antanaitis. "Evaluation of the Metabolic Relationship between Cows and Calves by Monitoring Calf Health and Cow Automatic Milking System and Metabolic Parameters." Animals 13, no. 16 (2023): 2576. http://dx.doi.org/10.3390/ani13162576.

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With this study, we investigated the relationship between a cow’s and calf’s metabolic state, and its effect on health status. To achieve this, 20 calves of primiparous and 20 calves of multiparous cows were selected. The calves were monitored for 30 days and scored for signs of disease, as described in McQuirk (2008); according to score, they were divided into healthier calves; the Low calf score group (LCS, 5–8), Medium calf score group (MCS, 9–12) and High calf score group (HCS, 14–17); or calves most prone to disease. Their mothers were monitored for the same period with a Lely Astronaut 3

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Pokhylko, Valeriy I., Olena M. Kovalova, Svitlana M. Tsvirenko, et al. "ELECTROCARDIOGRAPHIC CHANGES IN NEWBORNS FROM MOTHERS WITH METABOLIC SYNDROME." Wiadomości Lekarskie 74, no. 6 (2021): 1349–54. http://dx.doi.org/10.36740/wlek202106112.

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The aim: Analysis of electrocardiographic parameters in newborns from mothers with metabolic syndrome. Materials and methods: We conducted a prospective cohort trial of 125 newborns, which included the study of their anthropometric, clinical and laboratory indicators and, in particular, ECG parameters. The main group consisted of 40 children, born from mothers with diagnosed metabolic syndrome, the comparison group included 2 subgroups: 28 term newborn and 57 preterm, from mothers without metabolic syndrome. Results: In newborns from mothers with metabolic syndrome on a fragmentary ECG we reve

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Dissertations / Theses on the topic "Metabolic P system"

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McConn, Donavon J. "Metabolic and inhibitory differences between cytochromes P450 3A4 and 3A5 /." Thesis, Connect to this title online; UW restricted, 2001. http://hdl.handle.net/1773/7980.

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Dai, Yang. "Impact of the CYP3A5 polymorphism on the metabolic disposition of calcineurin inhibitors /." Thesis, Connect to this title online; UW restricted, 2006. http://hdl.handle.net/1773/7935.

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Dickmann, Leslie J. "Characterization of CYP2C9 residues important for conferring substrate specificity and inter-individual variability in drug metabolism /." Thesis, Connect to this title online; UW restricted, 2003. http://hdl.handle.net/1773/8184.

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Hutzler, James Matthew. "Factors affecting CYP2C9-mediated metabolism." Morgantown, W. Va. : [West Virginia University Libraries], 2001. http://etd.wvu.edu/templates/showETD.cfm?recnum=2204.

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Thesis (Ph. D.)--West Virginia University, 2001.<br>Title from document title page. Document formatted into pages; contains viii, 199 p. : ill. (some col.). Vita. Includes abstract. Includes bibliographical references (p. 176-195).

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Wennerholm, Agneta. "Characteristics of cytochrome P450-catalysed drug metabolism with focus on a black Tanzanian population /." Stockholm, 2003. http://diss.kib.ki.se/2003/91-7349-697-9/.

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Wurden, Colleen J. "Metabolism of carbamazepine and inhibitory drug interactions /." Thesis, Connect to this title online; UW restricted, 2000. http://hdl.handle.net/1773/7977.

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Ayscue, Robyn Renee. "Computer modeling of dapsone-mediated heteroactivation of flurbiprofen metabolism by CYP2C9." Morgantown, W. Va. : [West Virginia University Libraries], 2008. https://eidr.wvu.edu/etd/documentdata.eTD?documentid=5642.

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Thesis (Ph. D.)--West Virginia University, 2008.<br>Title from document title page. Document formatted into pages; contains viii, 174 p. : ill. (some col.). Includes abstract. Includes bibliographical references (p. 164-174).

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O'Mahony, Brian. "Clinical and toxicological significance of the involvement of the cytocrhome p450 system in the metabolism of 3,4-methylenedioxymethamphetamine." Doctoral thesis, Universitat Pompeu Fabra, 2008. http://hdl.handle.net/10803/7209.

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La 3,4-metilenodioximetanfetamina (MDMA, éxtasis) es una anfetamina sustituida de consumo frecuente y abusivo. La enzima principal que participa en el metabolismo de fase I de la MDMA, la isoforma 2D6 (CYP2D6) del citocromo P450, resulta también inhibida por la MDMA. Además, ésta es a la vez metabolizada por otras isoformas de CYP, por ejemplo la CYP1A2. La contribución de esta enzima y los posibles cambios en su actividad tras una administración de MDMA nunca han sido estudiados in-vivo. En consecuencia, se realizó un ensayo clínico donde los marcadores, dextrometorfano y cafeína se administr

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Ufer, Mike. "The in-vitro and in-vivo metabolism of the oral anticoagulant phenprocoumon as influenced by genetic polymorphisms of cytochrome P4502C9 /." Stockholm, 2004. http://diss.kib.ki.se/2004/91-7140-172-5/.

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Kabulski, Jarod L. "Development of Au-immobilized P450 platform for exploring the effect of oligomer formation on P450-mediated metabolism for In vitro to In vivo drug metabolism predictions." Morgantown, W. Va. : [West Virginia University Libraries], 2010. http://hdl.handle.net/10450/10892.

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Thesis (Ph. D.)--West Virginia University, 2010.<br>Title from document title page. Document formatted into pages; contains xiv, 180 p. : ill. (some col.). Includes abstract. Includes bibliographical references.

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Books on the topic "Metabolic P system"

1

1935-, Bock K. W., ed. Hepatic metabolism and disposition of endo- and xenobiotics: Proceedings of the 57th Falk Symposium held in Freiburg-im-Breisgau, Germany, October 8-10, 1990. Kluwer Academic Publishers, 1991.

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Ahlström, Marie. Cytochrome P450, metabolism and inhibition: Computational and experimental studies. Göteborg University, 2007.

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Cozza, Kelly L. Quick guide to the Cytochrome P450 system: Overview of drug interaction principles. American Psychiatric Pub., 2002.

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S, Lee Jae, Obach R. Scott, and Fisher Michael B, eds. Drug metabolizing enzymes: Cytochrome P450 and other enzymes in drug discovery and development. FontisMedia SA, 2003.

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Cozza, Kelly L. Concise guide to the cytochrome P450 system: Drug interaction principles for medical practice. American Psychiatric Pub., 2001.

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Emel, Arinç, Schenkman John B, Hodgson Ernest 1932-, and NATO Advanced Study Institute on Molecular Aspects of Drug Metabolizing Enzymes (1993 : Kus̜adası, Turkey), eds. Molecular aspects of oxidative drug metabolizing enzymes: Their significance in environmental toxicology, chemical carcinogenesis, and health. Springer-Verlag, 1995.

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B, Matchar David, United States. Agency for Healthcare Research and Quality., and Duke University Evidence-based Practice Center., eds. Testing for cytochrome P450 polymorphisms in adults with non-psychotic depression treated with selective serotonin reuptake inhibitors (SSRIs). Agency for Healthcare Research and Quality, 2007.

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(Editor), Karl-Walter Bock, W. Gerok (Editor), and S. Matern (Editor), eds. Hepatic Metabolism and Disposition of Endo- and Xenobiotics (Falk Symposium). Springer, 1991.

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Drug Metabolism Enzymes. Marcel Dekker, 2003.

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Neil B., M.d. Sandson. Drug Interactions Casebook: The Cytochrome P450 System and Beyond. American Psychiatric Publishing, 2003.

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Book chapters on the topic "Metabolic P system"

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Castellini, Alberto, Vincenzo Manca, and Yasuhiro Suzuki. "Metabolic P System Flux Regulation by Artificial Neural Networks." In Membrane Computing. Springer Berlin Heidelberg, 2010. http://dx.doi.org/10.1007/978-3-642-11467-0_15.

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Lombardo, Rosario, and Vincenzo Manca. "Arithmetical Metabolic P Systems." In Lecture Notes in Computer Science. Springer Berlin Heidelberg, 2011. http://dx.doi.org/10.1007/978-3-642-21344-1_30.

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Karp, Frank, and Rodney Croteau. "Hydroxylation of (-)-β-Pinene and (-)-α-Pinene by a Cytochrome P-450 System from Hyssop (Hyssopus Officinalis)." In Secondary-Metabolite Biosynthesis and Metabolism. Springer US, 1992. http://dx.doi.org/10.1007/978-1-4615-3012-1_17.

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Manca, Vincenzo. "Log-gain Principles for Metabolic P Systems." In Algorithmic Bioprocesses. Springer Berlin Heidelberg, 2009. http://dx.doi.org/10.1007/978-3-540-88869-7_28.

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Castellini, Alberto, and Vincenzo Manca. "MetaPlab: A Computational Framework for Metabolic P Systems." In Membrane Computing. Springer Berlin Heidelberg, 2009. http://dx.doi.org/10.1007/978-3-540-95885-7_12.

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Dahl, Alan R. "The Effect of Cytochrome P-450-Dependent Metabolism and Other Enzyme Activities on Olfaction." In Molecular Neurobiology of the Olfactory System. Springer US, 1988. http://dx.doi.org/10.1007/978-1-4613-0989-5_3.

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Ermakova, Inna, Alexey Leontievsky, Alexey Sviridov, Tatyana Shushkova, and Dmitriy Epiktetov. "Catabolism of organophosphonates: biochemistry, physiology and interactions of degrading bacteria in the environment." In ORGANOPHOSPHORUS NEUROTOXINS. Publishing Center RIOR, 2020. http://dx.doi.org/10.29039/42_253-287.

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The major contribution of microorganisms in metabolism of natural and synthetic phosphonates, the biochemical bases of these processes and possible interactions between degrading bacteria in natural and anthropogenic ecosystems are presented in the light of the recent data on significant role of reduced phosphorus compounds in the biosphere. Special emphasis is placed on C-P lyase and phosphonatase which are pivotal enzyme systems for catabolism of both natural and synthetic phosphonates. Modern data on structure, diversity, regulation and physiological role of both enzymes are reviewed and di

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Barrett, M., N. Polge, R. Baerg, L. Bradshaw, and C. Poneleit. "Role of Cytochrome P-450s in Herbicide Metabolism and Selectivity and Multiple Herbicide Metabolizing Cytochrome P-450 Activities in Maize." In Regulation of Enzymatic Systems Detoxifying Xenobiotics in Plants. Springer Netherlands, 1997. http://dx.doi.org/10.1007/978-94-015-8927-7_4.

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Brđanović, Damir. "Effect of Poly-phosphate Limitation on the Anaerobic Metabolism of Bio-P Bacteria." In Modeling Biological Phosphorus Removal in Activated Sludge Systems. CRC Press, 2021. http://dx.doi.org/10.1201/9780429332234-8.

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Chen, Bohang. "A Historico-Logical Re-assessment of Hans Driesch’s Vitalism." In History, Philosophy and Theory of the Life Sciences. Springer International Publishing, 2023. http://dx.doi.org/10.1007/978-3-031-12604-8_4.

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AbstractToday vitalism is widely dismissed as a metaphysical heresy. For instance, Brigandt and Love (Reductionism in biology. In: Zalta EN (ed) The stanford encyclopedia of philosophy, 2017) claimed that “the denial of physicalism by vitalism, the doctrine that biological systems are governed by forces that are not physico-chemical, is largely of historical interest” (p. 3). Perhaps the most “infamous” vitalist is the German biologist Hans Driesch. However, Driesch (In Rádl E (ed) Actes du Huitième Congrès International de Philosophie a Prague 2–7 septembre 1934. Comité d’Organisation du Cong

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Conference papers on the topic "Metabolic P system"

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Datta, Rupsa, Veronika Miskolci, Gina M. Gallego-López, et al. "Metabolic Characterization of Neutrophil Activation Using Label-Free Fluorescence Lifetime Imaging Microscopy." In Optical Molecular Probes, Imaging and Drug Delivery. Optica Publishing Group, 2025. https://doi.org/10.1364/omp.2025.om1e.4.

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In this work we employ fluorescence lifetime imaging microscopy of intrinsic metabolic co-factor NAD(P)H to quantify metabolic changes in neutrophils upon activation and metabolic pathway perturbations across biological systems.

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Ashar, Khoirun Nisa, Venty Suryanti, Abbilah Ero Mahdhani, Vicky Ahava Ferdinansyah, and Alifiananda Rahmatul Dafa Kesuma. "Utilization of <i>Escherichia coli</i> and Lapindo Mud on Microbial Fuel Cells (MFCs) System." In 8th International Conference on Advanced Material for Better Future. Trans Tech Publications Ltd, 2025. https://doi.org/10.4028/p-ozje64.

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This research investigates the utilization of Escherichia coli and Lapindo mud in a two-chamber Microbial Fuel Cells (MFCs) series. MFCs are tools that convert chemical energy into electrical energy with the help of catalytic reactions from microorganisms. This research uses a dual chamber reactor connected by a salt bridge, with graphite electrodes placed in each chamber and connected by copper cables. Lapindo mud contains heavy metals, such as Cu and Pb. In small amounts, heavy metals required for maintaining various biochemical and physiological functions in living organisms, but in greater

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Kulakovskis, Darius, Tomyslav Sledevic, Aurimas Gedminas, and Dalius Navakauskas. "Alternative implementations of metabolic P system in FPGA." In 2016 IEEE 4th Workshop on Advances in Information, Electronic and Electrical Engineering (AIEEE). IEEE, 2016. http://dx.doi.org/10.1109/aieee.2016.7821816.

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Kulakovskis, Darius, and Dalius Navakauskas. "Automation of metabolic P system implementation in FPGA: A case study." In 2015 IEEE 3rd Workshop on Advances in Information, Electronic and Electrical Engineering (AIEEE). IEEE, 2015. http://dx.doi.org/10.1109/aieee.2015.7367289.

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Marchetti, Luca, Vincenzo Manca, and Ivan Zelinka. "On the inference of deterministic chaos: Evolutionary algorithm and metabolic P system approaches." In 2014 IEEE Congress on Evolutionary Computation (CEC). IEEE, 2014. http://dx.doi.org/10.1109/cec.2014.6900434.

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Marcus, A. J., L. B. Safier, H. L. Ullman, N. Islam, M. J. Broekman, and C. V. Schacky. "NEW EICOSANOIDS FORMED DURING PLATELET-NEUTROPHIL INTERACTIONS." In XIth International Congress on Thrombosis and Haemostasis. Schattauer GmbH, 1987. http://dx.doi.org/10.1055/s-0038-1644626.

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In physiologic and pathologic processes such as hemostasis, thrombosis and inflammation, multiple cell types are brought into close proximity - thereby increasing the possibility of metabolic interactions in the microenvironment. Activated platelets synthesize12-hydroxyeicosatetraenoic acid (12-HETE) in the presence or absence of aspirin. During a cell-cell interaction, platelet 12-HETE is metabolized by a cytochrome P-450 enzyme system in unstimulated neutrophils to 12.20-dihydroxyeicosatetraenoic acid (12,20-DiHETE). Recently, we observed time-dependent formation of a new eicosanoid followin

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Norris, James A., Anthony P. Marsh, Kevin P. Granata, and Shane D. Ross. "Positive Feedback in Powered Exoskeletons: Improved Metabolic Efficiency at the Cost of Reduced Stability?" In ASME 2007 International Design Engineering Technical Conferences and Computers and Information in Engineering Conference. ASMEDC, 2007. http://dx.doi.org/10.1115/detc2007-35657.

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A broad objective of many lower extremity exoskeletons is to allow the wearer to expend less of their own energy for locomotion. Existing exoskeleton control algorithms are based on positive feedback. Forces are generated to augment movement initiated by the wearer. Positive feedback, however, can have destabilizing effects in dynamic systems. In fact, stability in these lower extremity exoskeletons is achieved by relying on the wearer’s neuromuscular system. Relying on the wearer to maintain stability may increase metabolic demand, which is counter productive to increasing efficiency. Thus, t

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Manca, Vincenzo, and Luca Marchetti. "XML Representation of Metabolic P Systems." In 2009 IEEE Congress on Evolutionary Computation (CEC). IEEE, 2009. http://dx.doi.org/10.1109/cec.2009.4983336.

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Kurnikova, Irina, Ramchandra Sargar, Alexi Pavlov, Zhanar Baisenbaeva, Natalia Zabrodina, and Maria Zavalina. "Quantitative assessments in evaluating the effectiveness of arterial hypertension treatment: new technologies." In 9th International Conference on Human Interaction and Emerging Technologies - Artificial Intelligence and Future Applications. AHFE International, 2023. http://dx.doi.org/10.54941/ahfe1002959.

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Background. In the practice of clinical research, it is traditionally accepted to evaluate parameters that characterize the degree of impairment or loss of the function of an organ or system, and not their preservation. A fundamental change in the approach distinguishes a new trend in modern medicine, which makes it possible to assess the degree of preservation of functional resources, which was the basis of this study.Study purpose: To develop a method for dynamic quantitative assessment of the severity of arterial hypertension and evaluate the relationship between a qualitative indicator of

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Obradović, Darija, Milica Radan, Marija Popović-Nikolić, Slavica Oljačić, and Katarina Nikolić. "THE MOLECULAR BASIS OF DRUG-PLASMA PROTEIN INTERACTION FOR CNS ACTIVE COMPOUNDS." In 1st INTERNATIONAL Conference on Chemo and BioInformatics. Institute for Information Technologies, University of Kragujevac, 2021. http://dx.doi.org/10.46793/iccbi21.375o.

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The human serum albumin (HSA) is well known for its extraordinary binding capacity for both endogenous and exogenous compounds, including a wide range of drugs. The goal of our investigation was to evaluate the distribution process for 15 CNS active compounds. The drug-plasma protein interaction was evaluated under simulative physiological conditions on the HSA-based stationary phase by using the mixture of Sørensen phosphate buffer (pH 7.40) and acetonitrile modifier as a mobile phase (84:16 v/v). The retention parameters (k) were used to approximate the % of protein-binding by calculating th

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Reports on the topic "Metabolic P system"

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Sionov, Edward, Nancy Keller, and Shiri Barad-Kotler. Mechanisms governing the global regulation of mycotoxin production and pathogenicity by Penicillium expansum in postharvest fruits. United States Department of Agriculture, 2017. http://dx.doi.org/10.32747/2017.7604292.bard.

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The original objectives of the study, as defined in the approved proposal, are: To characterize the relationship of CreA and LaeA in regulation of P T production To understand how PacC modulates P. expansumpathogenicity on apples To examine if other secondary metabolites are involved in virulence or P. expansumfitness To identify the signaling pathways leading to PAT synthesis Penicilliumexpansum, the causal agent of blue mould rot, is a critical health concern because of the production of the mycotoxinpatulin (PAT) in colonized apple fruit tissue. Although PAT is produced by many Penicilliums

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Rezaie, Shogofa, Fedra Vanhuyse, Karin André, and Maryna Henrysson. Governing the circular economy: how urban policymakers can accelerate the agenda. Stockholm Environment Institute, 2022. http://dx.doi.org/10.51414/sei2022.027.

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We believe the climate crisis will be resolved in cities. Today, while cities occupy only 2% of the Earth's surface, 57% of the world's population lives in cities, and by 2050, it will jump to 68% (UN, 2018). Currently, cities consume over 75% of natural resources, accumulate 50% of the global waste and emit up to 80% of greenhouse gases (Ellen MacArthur Foundation, 2017). Cities generate 70% of the global gross domestic product and are significant drivers of economic growth (UN-Habitat III, 2016). At the same time, cities sit on the frontline of natural disasters such as floods, storms and dr

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Alfano, James, Isaac Barash, Thomas Clemente, Paul E. Staswick, Guido Sessa, and Shulamit Manulis. Elucidating the Functions of Type III Effectors from Necrogenic and Tumorigenic Bacterial Pathogens. United States Department of Agriculture, 2010. http://dx.doi.org/10.32747/2010.7592638.bard.

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Many phytopathogenic bacteria use a type III protein secretion system (T3SS) to inject type III effectors into plant cells. In the experiments supported by this one-year feasibility study we investigated type III effector function in plants by using two contrasting bacterial pathogens: Pseudomonas syringae pv. tomato, a necrotrophic pathogen and Pantoea agglomerans, a tumorigenic pathogen. The objectives are listed below along with our major conclusions, achievements, and implications for science and agriculture. Objective 1: Compare Pseudomonas syringae and Pantoea agglomerans type III effect

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Prusky, Dov, Nancy P. Keller, and Amir Sherman. global regulation of mycotoxin accumulation during pathogenicity of Penicillium expansum in postharvest fruits. United States Department of Agriculture, 2014. http://dx.doi.org/10.32747/2014.7600012.bard.

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Background to the topic- Penicilliumas a postharvest pathogen and producer of the mycotoxin PAT. Penicilliumspp. are destructive phytopathogens, capable of causing decay in many deciduous fruits, during postharvest handling and storage; and the resulting losses can amount to 10% of the stored produce and the accumulation of large amounts of the mycotoxinpatulin. The overall goal of this proposal is to identify critical host and pathogen factors that modulate P. expansummycotoxin genes and pathways which are required for PAT production and virulence. Our preliminary results indicated that gluco

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Aly, Radi, and John I. Yoder. Development of resistant crop plants to parasitic weeds based on trans-specific gene silencing. United States Department of Agriculture, 2013. http://dx.doi.org/10.32747/2013.7598146.bard.

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Broomrapes (Orobanche/Phelipanchespp.) are holo parasitic plants that subsist on the roots of a variety of agricultural crops and cause severe losses to the yield quality and quantity. Effective methods for controlling parasitic weeds are scarce, with only a few known cases of genetic resistance. In the current study, we proposed an improved strategy for the control of parasitic weeds based on trans-specific gene-silencing of three parasite genes at once. We used two strategies to express dsRNA containing selected sequences of three Phelipancheaegyptiacagenes PaACS, PaM6PR and PaPrx1 (pma): tr

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Avihingsanon, Yingyos, Jongkonnee Wongpiyabovorn, and Nattiya Hirankarn. Biomarker discovery in systemic lupus erythematosus: genome-methylation approaches : Research report. Chulalongkorn University, 2010. https://doi.org/10.58837/chula.res.2010.15.

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Discovery of novel biomarkers in lupus nephritis Biomarkers are needed for making diagnosis and prognosis. In lupus nephritis, conventional tests like urinalysis or serum creatinine remain inadequate for patient care. In this proposal, we focused on non-invasive tools like blood and urine mRNAs or proteins. We chose candidate genes involving regulatory T-cell, B-lymphocyte signatures or vascular protective factors. Expression of regulatory cell signature (FOXP3) in peripheral blood mononuclear cells is associated with activity of lupus nephritis. We found FOXP3 mRNA levels in PBMCs from patien

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