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1

Kulakovskis, Darius, and Dalius Navakauskas. "Automated Metabolic P System Placement in FPGA." Electrical, Control and Communication Engineering 10, no. 1 (2016): 5–12. http://dx.doi.org/10.1515/ecce-2016-0001.

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Abstract An original Very High Speed Integrated Circuit Hardware Description Language (VHDL) code generation tool that can be used to automate Metabolic P (MP) system implementation in hardware such as Field Programmable Gate Arrays (FPGA) is described. Unlike P systems, MP systems use a single membrane in their computations. Nevertheless, there are many biological processes that have been successfully modeled by MP systems in software. This is the first attempt to analyze MP system hardware implementations. Two different MP systems are investigated with the purpose of verifying the developed
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Kulakovskis, Darius. "APPLICATION PROSPECTS OF METABOLIC P SYSTEM / METABOLINĖS P SISTEMOS TAIKYMO GALIMYBĖS." Mokslas – Lietuvos ateitis 7, no. 3 (2015): 285–90. http://dx.doi.org/10.3846/mla.2015.784.

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Metabolic P (MP) systems are a class of P systems and are based on metabolic process which is used by living organisms. We review for the purpose of experimental research the MP system development, implementation and modeling. To implement MP systems in dedicated hardware, some specifications need to be determined. We look into the possibility of modeling MP systems in fixed point arithmetic capable hardware and determine the minimal needed bit count for selected MP system model. A way to improve the accuracy of fixed point calculations is proposed, which includes the modification of MP gramma
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Manca, Vincenzo, Roberto Pagliarini, and Simone Zorzan. "A photosynthetic process modelled by a metabolic P system." Natural Computing 8, no. 4 (2008): 847–64. http://dx.doi.org/10.1007/s11047-008-9104-x.

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Pagliarini, Roberto, Giuditta Franco, and Vincenzo Manca. "An Algorithm for Initial Fluxes of Metabolic P Systems." International Journal of Computers Communications & Control 4, no. 3 (2009): 263. http://dx.doi.org/10.15837/ijccc.2009.3.2434.

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A central issue in systems biology is the study of efficient methods inferring fluxes of biological reactions by starting from experimental data. Among the different techniques proposed in the last years, the theory of Metabolic P systems, which is based on the Log-Gain principle, proved to be helpful for deducing biologi- cal fluxes from temporal series of observed dynamics. According to this approach, the algebraic systems provided by the Log-Gain principle determine the reaction fluxes underlying a system dynamics when initial fluxes are known. Here we propose a heuristic algorithm for esti
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Melanson, Edward L., Patty S. Freedson, Devra Hendelman, and Edward Debold. "Reliability and Validity of a Portable Metabolic Measurement System." Canadian Journal of Applied Physiology 21, no. 2 (1996): 109–19. http://dx.doi.org/10.1139/h96-010.

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The purpose of this study was to assess the reliability and validity of a portable metabolic system (TEEM 100) during submaximal and maximal [Formula: see text] exercise using a computer-based metabolic system as the reference system (REF). Between repeated trials of submaximal exercise at three constant loads, differences in ventilation [Formula: see text] and oxygen consumption [Formula: see text] were 0.2 ± 4.9 L∙min−1 and 0.03 ± 0.10 L∙min−1 for REF, and 1.9 ± 0.7 L∙min−1 and 0.00 ± 0.17 L∙min−1 for TEEM 100. Pooled intraclass reliability coefficients for [Formula: see text] and [Formula:
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Singh, Arushi, Poonam Mani, Shashi Prateek, Lalita Yadav, and Eshna Gupta. "Impact of levonorgestrel intrauterine system on metabolic parameters." International Journal of Reproduction, Contraception, Obstetrics and Gynecology 8, no. 3 (2019): 830. http://dx.doi.org/10.18203/2320-1770.ijrcog20190433.

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Background: Hormonal contraceptive is suggested to affect parameters like body mass index, body weight, blood pressure (BP), blood sugar, lipid protein, and liver function test (LFT) but effect of LNG-IUS on those parameters is still uncertain. The aim of the present study was to study the effects of LNG-IUS on the metabolic parameters.Methods: Sixty women who opted for LNG-IUS for various indications were included in the study. Lipid profile, liver function tests (LFT), glucose levels [fasting and post prandial (PP)], and hemoglobin (Hb) were tested. Bimanual genital examination and transvagi
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Becker, Wolfgang, Lukas Braun, Rodrigo Suarez-Ibarrol, and Arkadiusz Miernik. "Metabolic Imaging by Simultaneous FLIM of NAD(P)H and FAD." Current Directions in Biomedical Engineering 6, no. 3 (2020): 254–56. http://dx.doi.org/10.1515/cdbme-2020-3064.

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AbstractWe describe a metabolic imaging system based on simultaneous recording of lifetime images of NAD(P)H and FAD. The system uses one-photon excitation by ps diode lasers, scanning by galvanometer mirrors, confocal detection, and two parallel TCSPC FLIM recording channels. Two lasers, with wavelengths of 375nm and 410 nm, are multiplexed to alternatingly excite NAD(P)H and FAD. One FLIM channel detects in the emission band of NAD(P)H, the other in the emission band of FAD. For both channels, the data analysis delivers images of the amplitudes of the decay components, a1 and a2. We show tha
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Pogadayev, Daniil Vladimirovich, Larisa Аnatoliyevna Miniaylo, and Svetlana Viktorovna Gridneva. "ASSESSMENT OF OXIDATIVE METABOLIC SYSTEM PARAMETERS AFTER CORRECTION WITH THE FLAVONOID DIHYDROQUERCETIN." Scientific medical Bulletin of Ugra 32, no. 2 (2022): 181–83. http://dx.doi.org/10.25017/2306-1367-2022-32-2-181-183.

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A total of 71 residents, living for more than 10 years in the Khanty-Mansiysk Autonomous Region with poor-quality water treatment and not employed in the manufacturing sector, were examined: 29 (40,8%) men and 42 (59,2%) women, average age 38,3 ± 8,9 years. The indicators of POL above the reference values, and AOZ – below the physiologically optimal values were established. After receiving for metabolic correction antioxidant drug dihydroquercetin for a month there was a statistically significant decrease in primary (GPl, p=0.025) and secondary (TBA-AP, p=0,049) of LPO products, significant 1,
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Urbutis, Mingaudas, Dovilė Malašauskienė, Mindaugas Televičius, Vida Juozaitienė, Walter Baumgartner, and Ramūnas Antanaitis. "Evaluation of the Metabolic Relationship between Cows and Calves by Monitoring Calf Health and Cow Automatic Milking System and Metabolic Parameters." Animals 13, no. 16 (2023): 2576. http://dx.doi.org/10.3390/ani13162576.

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With this study, we investigated the relationship between a cow’s and calf’s metabolic state, and its effect on health status. To achieve this, 20 calves of primiparous and 20 calves of multiparous cows were selected. The calves were monitored for 30 days and scored for signs of disease, as described in McQuirk (2008); according to score, they were divided into healthier calves; the Low calf score group (LCS, 5–8), Medium calf score group (MCS, 9–12) and High calf score group (HCS, 14–17); or calves most prone to disease. Their mothers were monitored for the same period with a Lely Astronaut 3
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10

Pokhylko, Valeriy I., Olena M. Kovalova, Svitlana M. Tsvirenko, et al. "ELECTROCARDIOGRAPHIC CHANGES IN NEWBORNS FROM MOTHERS WITH METABOLIC SYNDROME." Wiadomości Lekarskie 74, no. 6 (2021): 1349–54. http://dx.doi.org/10.36740/wlek202106112.

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The aim: Analysis of electrocardiographic parameters in newborns from mothers with metabolic syndrome. Materials and methods: We conducted a prospective cohort trial of 125 newborns, which included the study of their anthropometric, clinical and laboratory indicators and, in particular, ECG parameters. The main group consisted of 40 children, born from mothers with diagnosed metabolic syndrome, the comparison group included 2 subgroups: 28 term newborn and 57 preterm, from mothers without metabolic syndrome. Results: In newborns from mothers with metabolic syndrome on a fragmentary ECG we reve
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Robledo-Millán, Carlos Raúl, María Regina Diaz-Domínguez, Ari Evelyn Castañeda-Ramírez, et al. "A Novel Metabolic Risk Classification System Incorporating Body Fat, Waist Circumference, and Muscle Strength." Journal of Functional Morphology and Kinesiology 10, no. 1 (2025): 72. https://doi.org/10.3390/jfmk10010072.

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Background: As metabolic diseases continue to rise globally, there is a growing need to improve risk assessment strategies beyond traditional measures such as BMI and waist circumference, which may fail to identify individuals at risk. This study develops and validates a novel metabolic risk classification system that incorporates body fat percentage (%BF), waist circumference (WC), and grip strength (GS) in Mexican adults. It aims to improve risk stratification and evaluate the association with metabolic syndrome. Methods: This cross-sectional study involved 300 young adults (18–22 years) fro
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Brown, Darcy M., Dan B. Dwyer, Samuel J. Robertson, and Paul B. Gastin. "Metabolic Power Method: Underestimation of Energy Expenditure in Field-Sport Movements Using a Global Positioning System Tracking System." International Journal of Sports Physiology and Performance 11, no. 8 (2016): 1067–73. http://dx.doi.org/10.1123/ijspp.2016-0021.

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The purpose of this study was to assess the validity of a global positioning system (GPS) tracking system to estimate energy expenditure (EE) during exercise and field-sport locomotor movements. Twenty-seven participants each completed a 90-min exercise session on an outdoor synthetic futsal pitch. During the exercise session, they wore a 5-Hz GPS unit interpolated to 15 Hz and a portable gas analyzer that acted as the criterion measure of EE. The exercise session was composed of alternating 5-minute exercise bouts of randomized walking, jogging, running, or a field-sport circuit (×3) followed
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Pavanasam, Velayutham, and Chandrasekaran Subramaniam. "Metabolic Algorithm for Software Requirement Engineering." Advanced Materials Research 267 (June 2011): 639–44. http://dx.doi.org/10.4028/www.scientific.net/amr.267.639.

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The objective of this work is to apply metabolic algorithm to the various items involved during the software development process. The metabolic algorithm is introduced in the rewriting mechanism of membrane or P system considering many time varying functions. Rules for requirement evolution, reaction between items in the membrane, communications between data items, process speed-up and abort rule are being proposed. The metabolic algorithm is applied for the transformation of user requirements into system requirements which can be further segregated into functional as well as non-functional re
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MANCA, VINCENZO, and LUCA MARCHETTI. "LOG-GAIN STOICHIOMETRIC STEPWISE REGRESSION FOR MP SYSTEMS." International Journal of Foundations of Computer Science 22, no. 01 (2011): 97–106. http://dx.doi.org/10.1142/s0129054111007861.

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MP systems are a class of P systems introduced for modeling metabolic processes. Here a regression method is presented for deducing a MP system exhibiting the dynamics of an observed metabolic system. In the procedure here described the knowledge of the stoichiometry of the system is combined with the log-gain principle of MP systems and is integrated with the Least Square Estimation method and with the stepwise regression approximation.
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15

Xiao, Yao, Mei-Jun Chen, Xu Shen, et al. "Metabolic Disorders in Patients with Central Nervous System Infections: Associations with Neurosyphilis." European Neurology 81, no. 5-6 (2019): 270–77. http://dx.doi.org/10.1159/000503626.

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Introduction: Recently, neurosyphilis was found to be associated with diabetes mellitus (DM). Whether the association was specific to neurosyphilis among central nervous system (CNS) infections, and whether neurosyphilis is associated with other prevalent metabolic disorders deserves further study. Methods: An in-depth cross-sectional study was conducted with 74 neurosyphilis patients and 74 sex- and age-matched patients with other CNS infections. DM-, hypertension-, and dyslipidemia-related factors were compared between patients with neurosyphilis and those with other CNS infections. Results:
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Molavi, Nader, Amir Ghaderi, and Hamid Reza Banafshe. "Examining Metabolic Profiles in Opioid-‎Dependent Patients ‎." International Journal of Medical Toxicology and Forensic Medicine 10, no. 3 (2020): 28681. http://dx.doi.org/10.32598/ijmtfm.v10i3.28681.

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Background: Drug abuse is a social burden and a public health disorder. Previous evidence suggested numerous illicit substances (e.g., opioids, amphetamines, cocaine, & cannabis) affect immune system functions, oxidative stress mechanisms, inflammatory cytokines, and reactive oxygen species production.
 This study aimed to determine the extent of these metabolic parameters in opioid-dependent patients. We also compared these patients with a healthy control group.
 Methods: This study was conducted in Amirie Clinic, Kashan, Iran. Plasma and serum samples from 50 illicit opioid use
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17

Ainegren, Mats, Kurt Jensen, and Hans Rosdahl. "Breathing resistance in automated metabolic systems is high in comparison with the Douglas Bag method and previous recommendations." Proceedings of the Institution of Mechanical Engineers, Part P: Journal of Sports Engineering and Technology 232, no. 2 (2017): 122–30. http://dx.doi.org/10.1177/1754337117715946.

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The purpose of this study was to investigate the resistance to breathing in metabolic systems used for the distribution and measurement of pulmonary gas exchange. A mechanical lung simulator was used to standardize selected air flow rates ([Formula: see text], L/s). The delta pressure (Δ p, Pa) between the ambient air and the air inside the equipment was measured in the breathing valve’s mouthpiece adapter for four metabolic systems and four types of breathing valves. Resistance for the inspiratory and expiratory sides was calculated as RES = (Δ p/[Formula: see text]) Pa/L/s. The results for r
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Pustovoyt, V. I., T. A. Astrelina, E. I. Balakin, et al. "Prediction of metabolic activity of rowing athletes based on serum biochemical analysis." Биофизика 68, no. 2 (2023): 396–403. http://dx.doi.org/10.31857/s0006302923020205.

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Determination of the metabolic state is an important topic in sports medicine. Biochemical and hematological blood parameters reflect the predominance of anabolic or catabolic processes in metabolism, these parameters depend on intensity and duration of workouts. The aim of the present study was to determine whether metabolic processes are dominant. 21 male rowing athletes (age: 22.55 ± 3.68 years, height: 189.62 ± 6.34 cm, weight: 88.65 ± 8.55 kg) participated in the experiment. Monitoring of blood concentrations in samples collected from participating athletes and measuring workout intensity
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Calosi, Piero, Samuel P. S. Rastrick, Chiara Lombardi, et al. "Adaptation and acclimatization to ocean acidification in marine ectotherms: an in situ transplant experiment with polychaetes at a shallow CO 2 vent system." Philosophical Transactions of the Royal Society B: Biological Sciences 368, no. 1627 (2013): 20120444. http://dx.doi.org/10.1098/rstb.2012.0444.

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Metabolic rate determines the physiological and life-history performances of ectotherms. Thus, the extent to which such rates are sensitive and plastic to environmental perturbation is central to an organism's ability to function in a changing environment. Little is known of long-term metabolic plasticity and potential for metabolic adaptation in marine ectotherms exposed to elevated p CO 2 . Consequently, we carried out a series of in situ transplant experiments using a number of tolerant and sensitive polychaete species living around a natural CO 2 vent system. Here, we show that a marine me
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Milinić, S., B. Kostić-Inić, and T. Novaković. "THE INFLUENCE OF THE METABOLIC SYNDROME ON THE ETIOPATHOGENESIS OF BILIARY CALCULOSIS." Praxis medica 37, no. 2 (2009): 61–63. http://dx.doi.org/10.70949/pramed200902296m.

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<p>The metabolic syndrome is characterized by a group of metabolic risk factors causing type 2 diabetes (DM2) and cardiovascular diseases. At the heart of this pathogenic disorder is insulin resistance. The metabolic syndrome is often accompanied by diseases of the gallbladder (chronic inflammations and calculosis). The goal of our study was to observe the changes made on the gallbladder with patients diagnosed with the metabolic syndrome, specifically the presence of calculosis and cholecystitis. The study involved 130 patients with the metabolic syndrome and 40 healthy subjects
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Williams, Natasha J., Chimene Castor, Azizi Seixas, Joseph Ravenell, and Girardin Jean-Louis. "Sleep Disorders and Symptoms in Blacks with Metabolic Syndrome: the Metabolic Syndrome Outcome Study (MetSO)." Ethnicity & Disease 28, no. 3 (2018): 193. http://dx.doi.org/10.18865/ed.28.3.193.

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<p class="Pa7"><strong>Introduction: </strong>Sleep disturbance is a major public health issue and is comorbid with the cluster of conditions associated with meta­bolic syndrome (MetS). Our study explored the presence of sleep disturbance, including daytime sleepiness, the risk for obstructive sleep apnea (OSA), and insomnia symp­toms, in a cohort of adult Black men and women with MetS.</p><p class="Pa7"><strong>Methods: </strong>Patients (n=1,013) from the Met­abolic Syndrome Outcome Study (MetSO), 2009-2012, met criteria for MetS based on guidelines
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Deng, Min, Rianne D. W. Vaes, Annemarie A. J. H. M. van Bijnen, Steven W. M. Olde Damink, and Sander S. Rensen. "Activation of the Complement System in Patients with Cancer Cachexia." Cancers 13, no. 22 (2021): 5767. http://dx.doi.org/10.3390/cancers13225767.

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Systemic inflammation is thought to underlie many of the metabolic manifestations of cachexia in cancer patients. The complement system is an important component of innate immunity that has been shown to contribute to metabolic inflammation. We hypothesized that systemic inflammation in patients with cancer cachexia was associated with complement activation. Systemic C3a levels were higher in cachectic patients with inflammation (n = 23, C-reactive protein (CRP) ≥ 10 mg/L) as compared to patients without inflammation (n = 26, CRP < 10 mg/L) or without cachexia (n = 13) (medians 102.4 (IQR 8
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Kim, Jong Min, Uk Lee, Jin Yong Kang, Seon Kyeong Park, Jong Cheol Kim, and Ho Jin Heo. "Matcha Improves Metabolic Imbalance-Induced Cognitive Dysfunction." Oxidative Medicine and Cellular Longevity 2020 (November 28, 2020): 1–19. http://dx.doi.org/10.1155/2020/8882763.

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This study was conducted to assess the protective effect of extract of match (EM) on high-fat diet- (HFD-) induced cognitive deficits in male C57BL/6 mice. It was found that EM improved glucose tolerance status by measuring OGTT and IPGTT with HFD-induced mice. EM protected behavioral and memory dysfunction in Y-maze, passive avoidance, and Morris water maze tests. Consumption of EM reduced fat mass, dyslipidemia, and inflammation in adipose tissue. Also, EM ameliorated hepatic and cerebral antioxidant systems. EM improved the cerebral cholinergic system by regulating ACh contents and expressi
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Nakano, Miho, Takuma Sakamoto, Yoshiyuki Itoh, et al. "The metabolic ability of swallowtails results in the production of bioactive substances from plant components." PLOS One 20, no. 7 (2025): e0321438. https://doi.org/10.1371/journal.pone.0321438.

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Host plant selection may depend on the metabolic system in herbivorous insects. Although oligophagous insects take up specific host plant components, how host plant components and their biological activities are altered through their metabolic systems remains unknown. Here, by examining gene expression of metabolic enzymes and components in the larval frass, we investigated the metabolic ability of Papilio memnon larvae fed with Citrus x paradisi (grapefruit) against host plant components. The gene expression levels of some metabolic enzymes were fluctuated between the larval midgut and the la
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Maurer Sost, Mônica, Yala Stevens, Bouke Salden, Freddy Troost, Ad Masclee, and Koen Venema. "Citrus Extract High in Flavonoids Beneficially Alters Intestinal Metabolic Responses in Subjects with Features of Metabolic Syndrome." Foods 12, no. 18 (2023): 3413. http://dx.doi.org/10.3390/foods12183413.

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The objective of this study was to investigate the effects of a citrus extract rich in citrus flavonoids on intestinal metabolic responses in subjects with features of metabolic syndrome, in an in vitro colon fermentation system (TIM-2) and fecal samples obtained from human subjects in an in vivo trial. In the TIM-2 system inoculated with fecal samples of volunteers with features of metabolic syndrome, continuous citrus extract supplementation (500 mg/day) resulted in increased cumulative short-chain fatty acid (SCFA) levels compared to the control condition, which was mainly due to increased
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Huo, Bei-Bei, Jun Shen, Xu-Yun Hua, et al. "Alteration of metabolic connectivity in a rat model of deafferentation pain: a 18F-FDG PET/CT study." Journal of Neurosurgery 132, no. 4 (2020): 1295–303. http://dx.doi.org/10.3171/2018.11.jns181815.

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OBJECTIVERefractory deafferentation pain has been evidenced to be related to central nervous system neuroplasticity. In this study, the authors sought to explore the underlying glucose metabolic changes in the brain after brachial plexus avulsion, particularly metabolic connectivity.METHODSRats with unilateral deafferentation following brachial plexus avulsion, a pain model of deafferentation pain, were scanned by small-animal 2-deoxy-[18F]fluoro-d-glucose (18F-FDG) PET/CT to explore the changes of metabolic connectivity among different brain regions. Thermal withdrawal latency (TWL) and mecha
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Grajales, Diana, Patricia Vázquez, Mónica Ruíz-Rosario, et al. "The second-generation antipsychotic drug aripiprazole modulates the serotonergic system in pancreatic islets and induces beta cell dysfunction in female mice." Diabetologia 65, no. 3 (2021): 490–505. http://dx.doi.org/10.1007/s00125-021-05630-0.

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Abstract Aims/hypothesis Second-generation antipsychotic (SGA) drugs have been associated with the development of type 2 diabetes and the metabolic syndrome in patients with schizophrenia. In this study, we aimed to investigate the effects of two different SGA drugs, olanzapine and aripiprazole, on metabolic state and islet function and plasticity. Methods We analysed the functional adaptation of beta cells in 12-week-old B6;129 female mice fed an olanzapine- or aripiprazole-supplemented diet (5.5–6.0 mg kg−1 day−1) for 6 months. Glucose and insulin tolerance tests, in vivo glucose-stimulated
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Tarantino, Giovanni, Maurizio Marra, Franco Contaldo, and Fabrizio Pasanisi. "Basal metabolic rate in morbidly obese patients with non-alcoholic fatty liver disease." Clinical & Investigative Medicine 31, no. 1 (2008): 24. http://dx.doi.org/10.25011/cim.v31i1.3138.

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Background. Non-Alcoholic Fatty Liver Disease occurs mainly in severly obese patients and its relationship to Metabolic Syndrome is increasingly recognized. The aim of this study was to determine energy production-utilization by measuring the Basal Metabolic Rate in severely obese patients, characterized by NAFLD, with or without Metabolic Syndrome. Then, the role of systemic inflammation was assessed. Patients and methods. Twenty severly obese men with Metabolic Syndrome were compared with a well-matched cohort of patients without Metabolic Syndrome. All showed hepatic steatosis at UltraSonog
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Moncure, Michael, Raja Salem, Kimberly Moncure, et al. "Central Nervous System Metabolic and Physiologic Effects of Laparoscopy." American Surgeon 65, no. 2 (1999): 168–72. http://dx.doi.org/10.1177/000313489906500215.

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We set out to determine whether the increases in intracranial pressure (ICP) associated with CO2 insufflation had any metabolic effect on the central nervous system in a head injury when compared with gasless laparoscopy (GL). To test this hypothesis, we looked at both the ICP and jugular bulb venous saturation (JVS), with and without a coexisting cerebral mass lesion. Twenty-five kilogram male pigs had tracheostomy, epidural balloon, pulmonary arterial catheter, arterial line, and jugular bulb catheter placed. Intravenous Pentobarbital was used for anesthesia. Either CO2 laparoscopy (CL; n =
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Kobuszewska, Anna, Dominik Kolodziejek, Michal Wojasinski, Tomasz Ciach, Zbigniew Brzozka, and Elzbieta Jastrzebska. "Study of Stem Cells Influence on Cardiac Cells Cultured with a Cyanide-P-Trifluoromethoxyphenylhydrazone in Organ-on-a-Chip System." Biosensors 11, no. 5 (2021): 131. http://dx.doi.org/10.3390/bios11050131.

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Regenerative medicine and stem cells could prove to be an effective solution to the problem of treating heart failure caused by ischemic heart disease. However, further studies on the understanding of the processes which occur during the regeneration of damaged tissue are needed. Microfluidic systems, which provide conditions similar to in vivo, could be useful tools for the development of new therapies using stem cells. We investigated how mesenchymal stem cells (MSCs) affect the metabolic activity of cardiac cells (rat cardiomyoblasts and human cardiomyocytes) incubated with a potent uncoupl
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Putri, Santy Irene, Astri Yunita, Hendra Dwi Kurniawan, and Aris Widiyanto. "IMPLEMENTASI PROGRAM PERENCANAAN PERSALINAN DAN PENCEGAHAN KOMPLIKASI (P4K) KAITANNYA DENGAN PENYEBAB KEMATIAN MATERNAL." KOSALA : Jurnal Ilmu Kesehatan 11, no. 2 (2023): 93–100. http://dx.doi.org/10.37831/kjik.v11i2.263.

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Latar belakang: Program Perencanaan Persalinan dan Pencegahan Komplikasi (P4K) adalah sebuah program pemerintah yang bertujuan untuk mendorong percepatan penurunan Angka Kematian Ibu (AKI). Apabila cakupan ibu hamil yang memperoleh parameter pemantauan P4K sampai dengan 80%, maka diharapkan angka kematian ibu yang diakibatkan oleh komplikasi dapat menurun hingga 6000 jiwa dari 2.052.000 per tahunnya. Penelitian ini bertujuan untuk menganalisis Penerapan Program Perencanaan Persalinan dan Pencegahan Komplikasi (P4K) terhadap penyebab kematian ibu. Subyek dan metode: penelitian ini merupakan pen
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Chester, Stephanie, Audrey Zucker-Levin, Daniel A. Melcher, Shelby A. Peel, Richard J. Bloomer, and Max R. Paquette. "Lower Limb Kinematics and Metabolic Cost During Elliptical Exercises and Treadmill Running." Journal of Applied Biomechanics 32, no. 2 (2016): 113–19. http://dx.doi.org/10.1123/jab.2015-0110.

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The purpose of this study was to compare knee and hip joint kinematics previously associated with anterior knee pain and metabolic cost among conditions including treadmill running (TR), standard elliptical (SE), and lateral elliptical (LE) in healthy runners. Joint kinematics and metabolic parameters of 16 runners were collected during all 3 modalities using motion capture and a metabolic system, respectively. Sagittal knee range of motion (ROM) was greater in LE (P < .001) and SE (P < .001) compared with TR. Frontal and transverse plane hip ROM were greater in LE compared with SE (P &l
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Pavlyshyn, Halyna, Iryna Sarapuk, Kateryna Kozak, and Olga Klishch. "Diagnostic value of markers of oxidative stress and metabolic disorders in preterm infants in the early neonatal period." Paediatria Croatica 65, no. 1 (2021): 7–12. http://dx.doi.org/10.13112/pc.393.

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The aim of the study was to evaluate the markers of oxidative stress and metabolic disorders in preterm infants and to examine their association with short-term outcomes in the early neonatal period to identify the predictors of unfavourable outcome. The study included 46 preterm infants, gestational age ≤32 weeks, in the early neonatal period, i.e. group 1 of 12 infants with lethal outcome and group 2 of 34 preterm infants with favourable outcome. Markers of metabolic disorders, oxidative stress and antioxidant system were analysed in cord blood and urine on the first/second day of life. Eval
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Pavlyshyn, Halyna, Iryna Sarapuk, Kateryna Kozak, and Olga Klishch. "Diagnostic value of markers of oxidative stress and metabolic disorders in preterm infants in the early neonatal period." Paediatria Croatica 64, no. 1 (2020): 7–12. http://dx.doi.org/10.13112/pc.429.

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The aim of the study was to evaluate the markers of oxidative stress and metabolic disorders in preterm infants and to examine their association with short-term outcomes in the early neonatal period to identify the predictors of unfavourable outcome. The study included 46 preterm infants, gestational age ≤32 weeks, in the early neonatal period, i.e. group 1 of 12 infants with lethal outcome and group 2 of 34 preterm infants with favourable outcome. Markers of metabolic disorders, oxidative stress and antioxidant system were analysed in cord blood and urine on the first/second day of life. Eval
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Gault, Mandy, Richard Clements, and Mark Willems. "Effect of Wearing the Cosmed K4b2 Metabolic System on 1 Mile Walking Performance in Older Adults." Journal of Human Kinetics 21, no. 1 (2009): 41–48. http://dx.doi.org/10.2478/v10078-09-0005-6.

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Effect of Wearing the Cosmed K4b2Metabolic System on 1 Mile Walking Performance in Older AdultsThis study examined in older adults the effects of wearing the Cosmed K4b2 metabolic system with face mask during the 1-mile Rockport Fitness Walking Test (RFWT). A randomised cross-over design was used (13 males, 12 females, age: 67±4 (yrs). Walking time, walking speed and final heart rate were recorded and predicted VO2max calculated. Participants had a constant walking speed during the RFWT (P = 0.24) not influenced by wearing the Cosmed K4b2. Using Bland-Altman analysis, bias for walking time, he
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Roytman, A. P., N. A. Sedova, E. A. Ivanova, and M. A. Godkov. "The importance of laboratory parameters of the lipid transport system and adipose tissue hormones in assessing the course of chronic." Russian Clinical Laboratory Diagnostics 67, no. 2 (2022): 85–90. http://dx.doi.org/10.51620/0869-2084-2022-67-2-85-90.

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The main manifestations of metabolic syndrome (MS) are disorders of carbohydrate and lipid metabolism and their hormonal regulation. The combined nature of metabolic disorders can significantly affect the course and prognosis of CHF in elderly people with metabolic syndrome. To determine the features of the combined effect of metabolic laboratory parameters and biological active factors of adipose tissue in patients with CHF and metabolic syndrome on the course of the disease. A comparison was made between a group of patients with CHF complicated by MS(n=37) and a group of patients with CHF wi
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Akter, Shamima, Md Mizanur Rahman, Md Majedul Islam, et al. "Disruption of components of vascular endothelial growth factor angiogenic signalling system in metabolic syndrome." Thrombosis and Haemostasis 109, no. 04 (2013): 696–705. http://dx.doi.org/10.1160/th12-09-0654.

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SummaryMetabolic syndrome (MetS) is associated with impaired angiogenesis, a process that is chiefly regulated by vascular endothelial growth factor (VEGF) upon binding to its specific receptors, VEGF-R1 and VEGF-R2. The purpose of the present study was to assess trends or patterns in plasma levels of VEGF and its soluble receptors in subjects with (MetS) or without (non-MetS) MetS; and further examine their association with clinical or metabolic parameters using a subpopu-lation of South Asian country. A total of 1,802 rural Bangladeshi women aged ≥15 years were studied using a population-bas
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Leben, Köhler, Radbruch, Hauser, and Niesner. "Systematic Enzyme Mapping of Cellular Metabolism by Phasor-Analyzed Label-Free NAD(P)H Fluorescence Lifetime Imaging." International Journal of Molecular Sciences 20, no. 22 (2019): 5565. http://dx.doi.org/10.3390/ijms20225565.

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In the past years, cellular metabolism of the immune system experienced a revival, as it has become clear that it is not merely responsible for the cellular energy supply, but also impacts on many signaling pathways and, thus, on diverse cellular functions. Label-free fluorescence lifetime imaging of the ubiquitous coenzymes NADH and NADPH (NAD(P)H-FLIM) makes it possible to monitor cellular metabolism in living cells and tissues and has already been applied to study metabolic changes both under physiologic and pathologic conditions. However, due to the complex distribution of NAD(P)H-dependen
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Paczkowska-Abdulsalam, Magdalena, Magdalena Niemira, Agnieszka Bielska, et al. "Evaluation of Transcriptomic Regulations behind Metabolic Syndrome in Obese and Lean Subjects." International Journal of Molecular Sciences 21, no. 4 (2020): 1455. http://dx.doi.org/10.3390/ijms21041455.

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Multiple mechanisms have been suggested to confer to the pathophysiology of metabolic syndrome (MetS), however despite great interest from the scientific community, the exact contribution of each of MetS risk factors still remains unclear. The present study aimed to investigate molecular signatures in peripheral blood of individuals affected by MetS and different degrees of obesity. Metabolic health of 1204 individuals from 1000PLUS cohort was assessed, and 32 subjects were recruited to four study groups: MetS lean, MetS obese, “healthy obese”, and healthy lean. Whole-blood transcriptome next
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Zheng, Jianfeng, Nan Wang, Ledan Zhao, Yajing Li, Jingjie Yu, and Shaopo Wang. "Microbial population changes and metabolic shift of candidatus accumulibacter under low temperature and limiting polyphosphate." Water Science and Technology 85, no. 4 (2022): 1107–19. http://dx.doi.org/10.2166/wst.2022.036.

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Abstract This study explored the microbial population dynamics of Accumulibacter (Acc) at low temperature and metabolic shift to limiting polyphosphate (Poly-P) in enhanced biological phosphorus removal (EBPR) system. The Accumulibacter-enriched EBPR systems, fed with acetate (HAc) and propionate (HPr) at 10 ± 1 °C respectively, were operated for 60 days in two identical SBR reactors (SBR-1 and SBR-2). The phosphorus removal performance in two systems was stable at 10 ± 1 °C, while the microbial community structure changed. Compared with the population structure in seed sludge, Accumulibacter
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Gonchar, Natalya V., Аnzhela А. Аvakyan, Svetlana N. Chuprova, and Nikolay V. Slizovskiy. "Changes of morphofunctional state of cardiovascular system in adolescents with metabolic syndrome manifestations." Pediatrician (St. Petersburg) 12, no. 1 (2021): 21–30. http://dx.doi.org/10.17816/ped12121-30.

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The results of investigation of features of morphofunctional state of cardiovascular system in adolescents with manifestations of metabolic syndrome depending on presence of hyperuricemia are presented. In the cardiorheumatology department of the hospital, 34 adolescent patients were observed. Criteria for inclusion in the study: the presence of increased blood pressure levels, increased body mass index values. Depending on serum uric acid levels, patients were divided into two groups: group 1 patients without hyperuricemia (n = 18) and group 2 patients with hyperuricemia (n = 16). Functional
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Vissing, J., B. Sonne, and H. Galbo. "Role of metabolic feedback regulation in glucose production of running rats." American Journal of Physiology-Regulatory, Integrative and Comparative Physiology 255, no. 3 (1988): R400—R406. http://dx.doi.org/10.1152/ajpregu.1988.255.3.r400.

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Hepatic glucose production (Ra) was studied in phlorizin (P)- and saline (C)-infused rats running for 35 min at 21 m/min in the postabsorptive state (series I) or 18 m/min in the fed state (series II). Phlorizin-induced increase in glucose clearance would increase or not affect Ra, depending on whether metabolic feedback mechanisms or central command from central nervous system (CNS), respectively, regulate Ra during exercise. Initial exercise-induced increases in Ra were similar in P and C rats of both series, although glucose clearance was higher and plasma glucose lower, however not hypogly
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Bell, Christopher, Douglas R. Seals, Mary Beth Monroe, et al. "Tonic Sympathetic Support of Metabolic Rate Is Attenuated with Age, Sedentary Lifestyle, and Female Sex in Healthy Adults." Journal of Clinical Endocrinology & Metabolism 86, no. 9 (2001): 4440–44. http://dx.doi.org/10.1210/jcem.86.9.7855.

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We recently demonstrated in young adult humans that the sympathetic nervous system contributes to the control of resting metabolic rate via tonic β-adrenergic receptor stimulation. In the present follow-up study we determined the respective effects of age, habitual exercise status, and sex on this regulatory mechanism. Resting metabolic rate (ventilated hood, indirect calorimetry) was determined in 55 healthy sedentary or endurance exercise-trained adults, aged 18–35 or 60–75 yr (29 men and 26 women), before (baseline) and during the infusion of either a nonselective β-adrenergic receptor anta
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Petković, Z., and M. Mirković. "GOUT - DIAGNOSTIC DIAGNOSTIC AND THERAPY THERAPY - case raport." Praxis medica 34, no. 2 (2006): 107–8. http://dx.doi.org/10.70949/pramed200602164p.

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<p>Gout is a metabolic arthropathy caused by abnormal deposition of crystal histological they are urats (salts) of mononatrium in the joints and periatricular connective tissue. In 70% cases, decreased renal function in urats’excretion is responsible for hyperuricaemya. The other causes are mostly metabolic: increased (take in) of food wich contains mostly meat (purins) and increased synthesis of purin due to defective enzyme system (i.e. Lesch-Nyhan Sy)</p>
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Sasmaz, Hatice, and Yilmaz Mehmet Birhan. "Coronary Collaterals in Obese Patients: Impact of Metabolic Syndrome." Angiology 60, no. 2 (2008): 164–68. http://dx.doi.org/10.1177/0003319708316007.

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Obesity is a growing pandemic. Among obese patients with significant coronary artery stenosis, development of coronary collaterals was investigated. Consecutive 104 obese patients with stable angina pectoris were enrolled. Coronary collaterals were assessed according to the Cohen and Rentrop grading system and classified into 2 as those with poor collaterals (grade 0–1, Group 1) and those with good collaterals (grade 2–3, Group 2). Group 1 had higher body mass index, shorter duration of angina pectoris than Group 2. Poor collaterals were present in 82.3% and 59.5% of patients with and without
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Vieira, Edna Cunha, Maria do Rosário Gondim Peixoto, and Erika Aparecida da Silveira. "Prevalence and factors associated with Metabolic Syndrome in elderly users of the Unified Health System." Revista Brasileira de Epidemiologia 17, no. 4 (2014): 805–17. http://dx.doi.org/10.1590/1809-4503201400040001.

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OBJECTIVE: To evaluate the prevalence and factors associated with metabolic syndrome in the elderly. METHODS: Cross-sectional study, with 133 individuals randomly selected in the Unified Health System in Goiania, Goiás. The following variables were researched: anthropometric (BMI, waist circumference, fat percentage by Dual X-ray absorptiometry), sociodemographic (gender, age, color, income, marital status and years of schooling), lifestyle (physical activity, smoking and risk alcohol consumption) and food intake (risk and protective foods). The metabolic syndrome was assessed according to har
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Schobersberger, Wolfgang, Georg Hoffmann, Dietmar Fries, et al. "AMAS (Austrian Moderate Altitude Study)-2000: Effects of Hiking Holidays at Moderate Altitude on Immune System Markers in Persons with Metabolic Syndrome." Pteridines 15, no. 4 (2004): 149–54. http://dx.doi.org/10.1515/pteridines.2004.15.4.149.

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Abstract Recent studies have shown a strong association between indices of inflammation and metabolic Syndrome. Proinflammatory mediators like tumor necrosis factor-α may act as a trigger for insulin insensitivity. Therefore, patients with metabolic Syndrome might be at higher risk of insulin resistance when confronted with additional Stimuli of the immune system. These Stimuli are not restricted to the presence of pathogens but include environmental factors like physical exercise and hypoxemia as well. With respect to these interdependencies, one may assume higher risk for patients with metab
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Kulakovskis, Darius. "INTRAVENINIO GLIUKOZĖS TOLERANCIJOS TESTO METABOLINĖS P SISTEMOS ĮGYVENDINIMAS APIBENDRINTUOJU KOMBINACINIU BŪDU / INTRAVENOUS GLUCOSE TOLERANCE TEST METABOLIC P SYSTEM IMPLEMENTED USING UNIFIED COMBINATIVE TECHNIQUE." Mokslas - Lietuvos ateitis 11 (April 15, 2019): 1–5. http://dx.doi.org/10.3846/mla.2019.9429.

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Metabolic P (MP) systems are a part of the infobiotics research field. The intravenous glucose tolerance test (IVGTT) MP system models glucose-insulin interactions. MP system implementation in software is well researched, although there is a lack of techniques for hardware implementation, specifically with field programmable gate arrays. In this article the existing techniques are examined first, including combinative, single digital signal processor element, and pipelined. Then the specifics of six different IVGTT MP systems are analyzed. Having in mind these specifics, a new unified combinat
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Kapoor, Saumya, Gurudutt Dubey, Samima Khatun, and Prasad V. Bharatam. "Remdesivir: Mechanism of Metabolic Conversion from Prodrug to Drug." Current Drug Metabolism 23, no. 1 (2022): 73–81. http://dx.doi.org/10.2174/1389200223666211228160314.

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Background: Remdesivir (GS-5734) has emerged as a promising drug during the challenging times of COVID-19 pandemic. Being a prodrug, it undergoes several metabolic reactions before converting to its active triphosphate metabolite. It is important to establish the atomic level details and explore the energy profile of the prodrug to drug conversion process. Methods: In this work, Density Functional Theory (DFT) calculations were performed to explore the entire metabolic path. Further, the potential energy surface (PES) diagram for the conversion of prodrug remdesivir to its active metabolite wa
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Lee, Jong Won, Han Kil Kim, and Hoe Kyung Jung. "User Analysis Mechanisms based Mobile Fitness System." International Journal of Electrical and Computer Engineering (IJECE) 6, no. 6 (2016): 3154. http://dx.doi.org/10.11591/ijece.v6i6.13267.

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<p>Modern men have health problems caused by lack of exercise than in the past. But most modern people do not know what to do exercise. Mobile systems for fitness to solve this problem have been developed. In this paper, by analyzing the user's BMI (Body Mass Index) Index and BMR (Basal Metabolic Rate) value, the data is made available. The processed data is provided to the user which proposes the right exercise and the appropriate level of exercise intensity, for exercise machines. This is different from detecting the movement, like the existing system, and a fitness value showing the c
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