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Journal articles on the topic 'Metabolic syndrome; gallstones'

Author: Grafiati

Published: 5 June 2025

Last updated: 2 August 2025

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1

Ata, Naim, Metin Kucukazman, Bunyamin Yavuz, et al. "The Metabolic Syndrome Is Associated with Complicated Gallstone Disease." Canadian Journal of Gastroenterology 25, no. 5 (2011): 274–76. http://dx.doi.org/10.1155/2011/356761.

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BACKGROUND: Gallstone disease (GD) is a common condition worldwide. Several studies demonstrated that the presence of gallstones is strongly associated with cardiovascular disease. The metabolic syndrome is a highly prevalent cardiovascular condition.OBJECTIVE: To examine the relationship between complicated GD (CGD) and the metabolic syndrome or its components.METHODS: Two hundred seventeen patients with gallstones were examined. All patients underwent biliary ultrasonography after a complete medical history and laboratory examination. Data collection for the diagnosis of metabolic syndrome i

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Cojocaru, Doina-Clementina, Florin Mitu, Cristina Dascălu, Alina Manole, and Corina Dima-Cozma. "The predictors of cholelithiasis in female patients with metabolic syndrome." Open Medicine 9, no. 1 (2014): 108–14. http://dx.doi.org/10.2478/s11536-013-0255-5.

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AbstractCholesterol gallstone disease is often associated with the metabolic syndrome. Female gender is an unmodifiable risk factor for cholelithiasis and, in its turn, the metabolic syndrome features a sexual dimorphism which warns that a global approach might overlook important discrimination. We carried out a retrospective analytical case-control study in order to perform a comparative analysis between two groups of female patients with metabolic syndrome and gallstones (n=60) or without gallstones (n=65). All the patients were investigated by abdominal ultrasound and met at least three cri

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Sheeba R, Siddeg Fadul Siddeg Fadul, Mohanned Mohammed Noor Elimam Abdallah, and Mohammed Imran. "Gall stones in metabolic syndrome- addressing the risks in obese individuals." International Journal of Frontiers in Medicine and Surgery Research 6, no. 2 (2024): 060–66. http://dx.doi.org/10.53294/ijfmsr.2024.6.2.0041.

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Significant research has been dedicated in recent years to elucidating the pathophysiologic mechanisms behind gallstone development, but the epidemiology of gallstone disease has received comparatively little focus. Numerous studies have emphasized the correlation between metabolic syndrome and gallstones. In this study, we found a positive correlation between complicated gall stones and metabolic syndrome. Hence, screening of obese patient or those with PCOS/uncontrolled diabetes, should be introduced in the protocol for facilitate early diagnosis of gall stones.

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Matalayeva, S. Yu. "Gallstone disease in children and comorbiditi." Rossiyskiy Vestnik Perinatologii i Pediatrii (Russian Bulletin of Perinatology and Pediatrics) 66, no. 3 (2021): 34–39. http://dx.doi.org/10.21508/1027-4065-2021-66-3-34-39.

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The article provides current information on comorbid diseases in both adults and children with cholelithiasis. It describes their pathogenetic relationship with the formation of gallstones. The authors highlight the causal factors in the development of both gallstone disease and accompanying comorbid conditions. They demonstrate the generality of metabolic disorders in cholelithiasis and metabolic syndrome. The article describes the mechanisms of formation of both cholesterol and pigmented gallstones, which can be formed against the background of both somatic and infectious diseases. The artic

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Shtygasheva, O. V., E. S. Ageeva, and S. V. Chmykhalo. "Conservatism and divergence in the semiotics cholelithiasis." Experimental and Clinical Gastroenterology, no. 8 (January 18, 2023): 63–69. http://dx.doi.org/10.31146/1682-8658-ecg-204-8-63-69.

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The aim of the study was to analyze the patterns associated with the risk of developing gallstone disease. Material and methods. The selection of signs of metabolic syndrome among patients of the hospital contingent with cholelithiasis, depending on gender and age, was carried out. There are 271 patients in the general population, of which 227 are women and 49 are men. Statistical processing of research results using the Statistica 8.0 applied software package. Results. Differences in etiology and pathogenesis lead to divergence of the phenotype of patients with cholelithiasis. At the same tim

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Mohssen, Ahmed, Andreea Alexandra Nicola, Denisa Predeţeanu, and Narcis Copcă. "The Uncertain Link Between Gallstone Disease and Colorectal Cancer." Internal Medicine 18, no. 3 (2021): 71–81. http://dx.doi.org/10.2478/inmed-2021-0168.

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Abstract Colorectal cancer (CRC) is one of the most commonly diagnosed cancers worldwide and is a major cause of cancer-related mortality. While environmental and genetic factors have a major and well-known contribution in its pathogenesis, research has suggested that nutrition and lifestyle may also play a central role in the development of this neoplasm. Moreover, metabolic, hormonal and biochemical changes in the digestive tract can create a favorable ground for tumor development in the colonic epithelium. Gallstone disease are a very common gastrointestinal disease that often remains asymp

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Thamer, Sanaa Jameel. "Pathogenesis, Diagnosis and Treatment of Gallstone Disease A Brief Review." Biomedicine and Chemical Sciences 1, no. 2 (2022): 70–77. http://dx.doi.org/10.48112/bcs.v1i2.99.

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Gallstone disease is a gastrointestinal disease that results from the dysfunction of cholesterol, bile, and bilirubin metabolism. Gallstones in the gallbladder are common and form through cholelithiasis. They can also grow in biliary ducts through choledocholithiasis. In industrial countries, gallstone disease has increased in prevalence and affects up to 20% of the adult population. Its major risk factors are female gender, age, obesity, type 2 diabetes, rapid weight loss, physical inactivity, and genetic traits. Various systems for gallstone classification are available. Gallstones are class

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Sanaa, Jameel Thamer. "Pathogenesis, Diagnosis and Treatment of Gallstone Disease A Brief Review." Biomedicine and Chemical Sciences, no. 2 (April 1, 2022): 70–77. https://doi.org/10.48112/bcs.v1i2.99.

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Gallstone disease is a gastrointestinal disease that results from the dysfunction of cholesterol, bile, and bilirubin metabolism. Gallstones in the gallbladder are common and form through cholelithiasis. They can also grow in biliary ducts through choledocholithiasis. In industrial countries, gallstone disease has increased in prevalence and affects up to 20% of the adult population. Its major risk factors are female gender, age, obesity, type 2 diabetes, rapid weight loss, physical inactivity, and genetic traits. Various systems for gallstone classification are available. Gallstones are class

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Palaparthy, Samson Subhash, Anjini Suvarchala Devi Chinta, Sirisha Bevunapalli, U. Deepthi N, and Bevunapalli Rakesh. "Biochemical Composition of Gall Stones among the Indian Population." International Journal of Toxicological and Pharmacological Research 14, no. 12 (2024): 99–101. https://doi.org/10.5281/zenodo.14622197.

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<strong>Introduction: </strong>Gallstones, a common biliary disorder in India, are classified as cholesterol, pigment, or mixed types, influenced by genetics, diet, obesity, and metabolic syndrome. This study aims to analyze the biochemical composition of gallstones in the Indian population, focusing on regional and demographic variations to guide prevention and treatment strategies. <strong>Methods: </strong>This prospective study, conducted at Konaseema Institute of Medical Sciences, analyzed gallstones from cholecystectomy patients (aged >18 years) between August 2022 and

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Di Ciaula, Agostino, David Q. H. Wang, Leonilde Bonfrate, and Piero Portincasa. "Current Views on Genetics and Epigenetics of Cholesterol Gallstone Disease." Cholesterol 2013 (April 14, 2013): 1–10. http://dx.doi.org/10.1155/2013/298421.

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Cholesterol gallstone disease, one of the commonest digestive diseases in western countries, is induced by an imbalance in cholesterol metabolism, which involves intestinal absorption, hepatic biosynthesis, and biliary output of cholesterol, and its conversion to bile acids. Several components of the metabolic syndrome (e.g., obesity, type 2 diabetes, dyslipidemia, and hyperinsulinemia) are also well-known risk factors for gallstones, suggesting the existence of interplay between common pathophysiological pathways influenced by insulin resistance, genetic, epigenetic, and environmental factors

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Altomare, Donato F., Maria T. Rotelli, and Nicola Palasciano. "Diet After Cholecystectomy." Current Medicinal Chemistry 26, no. 19 (2019): 3662–65. http://dx.doi.org/10.2174/0929867324666170518100053.

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Patients with gallstones are often affected by alimentary disorders contributing to the onset of gallstones disease. Cholecystectomy can have nutritional and metabolic consequences in the short-term (diarrhea, abdominal pain and bloating) and in the long-term (increased Body Mass Index with metabolic syndrome, gastritis, liposoluble vitamin deficiency). Pathogenic mechanisms behind these disturbances are reviewed and the need for an early post-operative nutritional intervention based on low-lipid, high-fibers diet, is highlighted.

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Man, Sailimai, Yongxiang Gao, Jun Lv, et al. "Metabolically healthy obesity was significantly associated with increased risk of gallstones." European Journal of Endocrinology 186, no. 2 (2022): 275–83. http://dx.doi.org/10.1530/eje-21-0802.

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Objective The risk of gallstones among metabolically healthy obesity (MHO) individuals is largely unexplored. Therefore, the present study investigated the association between MHO and gallstones in a health check-up cohort of Chinese adults. Design A prospective cohort study. Methods Participants included 58 862 individuals from the MJ health check-up cohort aged ≥ 18 years without a history of gallstones at baseline. Gallstones were diagnosed using abdominal B-type ultrasound. Metabolically healthy was defined as not having any one of the components of metabolic syndrome. Obesity was identifi

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Sang, Jae Hong, Nam Kyun Ki, Jae Hwan Cho, Jae Ouk Ahn, and Jae Gun Sunwoo. "Correlations between metabolic syndrome, serologic factors, and gallstones." Journal of Physical Therapy Science 28, no. 8 (2016): 2337–41. http://dx.doi.org/10.1589/jpts.28.2337.

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14

Grundy, Scott M. "Cholesterol gallstones: a fellow traveler with metabolic syndrome." American Journal of Clinical Nutrition 80, no. 1 (2004): 1–2. http://dx.doi.org/10.1093/ajcn/80.1.1.

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Dragan, Klaric, Martinis Marta, and Klaric Marta. "Metabolic syndrome: A case report." Annals of Clinical Endocrinology and Metabolism 5, no. 1 (2021): 031–35. http://dx.doi.org/10.29328/journal.acem.1001022.

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Metabolic syndrome composed of abdominal obesity, atherogenic dyslipidemia, raised blood pressure, insulin resistance and/or glucose intolerance, proinflammatory state and prothrombotic state is a complex multisystem disorder. It is well known that patients with metabolic syndrome have increased cardiovascular risk and risk of developing diabetes type II. But besides these well known risk states, there are other conditions such as polycystic ovary syndrome, fatty liver, cholesterol gallstones, asthma, sleep disturbances and some forms of cancer associated with a metabolic syndrome. In this cas

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A, Bhan. "To Find Incidence of Metabolic Syndrome in Patients with Gallstones Admitted in Surgery Department." Journal of Medical Science And clinical Research 05, no. 01 (2017): 15362. http://dx.doi.org/10.18535/jmscr/v5i1.27.

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YENER, Oktay, Fikret AKSOY, Mustafa DEMIR, Alp OZCELIK, and Canan ERENGUL. "Gallstones associated with nonalcoholic steatohepatitis (NASH) and metabolic syndrome." Turkish Journal of Gastroenterology 21, no. 4 (2010): 411–15. http://dx.doi.org/10.4318/tjg.2010.0128.

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Wang, Helen H., Piero Portincasa, Min Liu, Patrick Tso, and David Q. H. Wang. "An Update on the Lithogenic Mechanisms of Cholecystokinin a Receptor (CCKAR), an Important Gallstone Gene for Lith13." Genes 11, no. 12 (2020): 1438. http://dx.doi.org/10.3390/genes11121438.

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The cholecystokinin A receptor (CCKAR) is expressed predominantly in the gallbladder and small intestine in the digestive system, where it is responsible for CCK’s regulation of gallbladder and small intestinal motility. The effect of CCKAR on small intestinal transit is a physiological response for regulating intestinal cholesterol absorption. The CCKAR gene has been identified to be an important gallstone gene, Lith13, in inbred mice by a powerful quantitative trait locus analysis. Knockout of the CCKAR gene in mice enhances cholesterol cholelithogenesis by impairing gallbladder contraction

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Baratta, Francesco, Daniele Pastori, Nicholas Cocomello, et al. "Sex-Related Differences in the Association between Metabolic Syndrome and Gallstone Disease." International Journal of Environmental Research and Public Health 18, no. 4 (2021): 1958. http://dx.doi.org/10.3390/ijerph18041958.

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Metabolic syndrome (MetS) and gallstone disease (GD) share common risk factors. Several epidemiological studies reported that subjects with Mets are more likely to have GD than those without and that cholecystectomy (CHO) may increase the risk of MetS. The aim of the study was to evaluate the association between MetS and GD in a large cohort of patients with metabolic risk factors in Italy. The study was performed in 620 consecutive outpatients referring to the University outpatients’ clinic for the management of cardiovascular risk factors. MetS were diagnosed according to the ATPIII Expert P

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Uspenskiy, Yu.P., Yu.A. Fominykh, K.N. Nadzhafova, A.V. Kosheev, and F.M. Sultanova. "The Role Of Serum Lipids In The Development of Gallstone Disease." University therapeutic journal 1, no. 1 (2019): 59–71. https://doi.org/10.5281/zenodo.3824208.

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Gallstones is a complex disease, the causes of its occurrence are not fully understood. There are described cholelithiasis risk factors, and the role of the metabolic syndrome in this process. This article presents a review of literature data on the role of serum lipids in the formation of gallbladder stones. We have discussed possible pathogenetic mechanisms, which demonstrate direct and inverse relationships between the development of gallstone disease and fractions of the blood lipid spectrum. The data of published clinical research about the relationship between the content of serum lipids

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Kumar B., Sathish, Venkat Reddy, Suryanarayana Reddy V., Ram Mohan C., and Jahnavi Koneru. "A study of clinical presentations and management of cholelithiasis." International Surgery Journal 6, no. 6 (2019): 2164. http://dx.doi.org/10.18203/2349-2902.isj20192386.

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Background: Cholelithiasis or gallstones, is one of the most common and costly of all the gastrointestinal diseases. Gallstones are associated with high-calorie diets, type 2 diabetes mellitus, dyslipidemia, hyperinsulinism, obesity, and metabolic syndrome. The aim of the study was to analysis the incidence, clinical presentations, and management of cholelithiasis in tertiary care Hospital at Karimnagar, Telangana, India.Methods: This study was a prospective study; total 50 patients were enrolled in this study. The study was conducted at Department of Chalmeda Anand Rao Institute of Medical Sc

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Chatterjee, Rupak, Shatavisa Mukherjee, Partha Sarathi Karmakar, and Netai Pramanik. "Lean Metabolic Syndrome vis-à-vis Obese Metabolic Syndrome: Observations from an Eastern Indian Tertiary Set-up." Journal of the Practice of Cardiovascular Sciences 10, no. 1 (2024): 25–29. http://dx.doi.org/10.4103/jpcs.jpcs_5_24.

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Background: Metabolic syndrome (MetS) in obese is a fairly common entity. However, excluding the waist circumference (WC) criteria, other components of the MetS are also seen in lean or nonobese people. Our study aimed to determine the prevalence of lean MetS among newly diagnosed MetS cases and compare the biochemical parameters and insulin resistance in lean versus overweight/obese MetS. Methods: A cross-sectional, observational study was conducted over 12 months and included adult patients of either sex, newly diagnosed with MetS. Fever cases, infections such as tuberculosis/HIV/chronic inf

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Uche-Anya, Eugenia, Jane Ha, Raji Balasubramanian, Kathryn M. Rexrode, and Andrew T. Chan. "Metabolomic profiles of incident gallstone disease." BMJ Open Gastroenterology 11, no. 1 (2024): e001417. http://dx.doi.org/10.1136/bmjgast-2024-001417.

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Background and aimsGallstone disease affects ≥40 million people in the USA and accounts for health costs of ≥$4 billion a year. Risk factors such as obesity and metabolic syndrome are well established. However, data are limited on relevant metabolomic alterations that could offer mechanistic and predictive insights into gallstone disease. This study prospectively identifies and externally validates circulating prediagnostic metabolites associated with incident gallstone disease.MethodsFemale participants in Nurses’ Health Study (NHS) and Nurses’ Health Study II (NHS II) who were free of known

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Kumar, K. Jagadish, S. V. Akshaya, Manjunath Vaddamabal Gopalkrishna, and H. R. Nandish. "Gallstone association in a jaundiced child due to hepatitis A infection." Muller Journal of Medical Sciences and Research 16, no. 1 (2025): 92–95. https://doi.org/10.4103/mjmsr.mjmsr_25_25.

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ABSTRACT Gallstones (GSs) are rare in children. The incidence of GSs has been increasing due to the utility of sonography in modern practice. Common causes of GSs in children include hemolytic anemias, obesity, metabolic syndrome, prematurity, necrotizing enterocolitis, cystic fibrosis, and total parenteral nutrition. Several studies evaluated the association between hepatic viral infection and GSs. There is a significantly increased risk of GSs among hepatitis C virus-infected patients and no significant association with hepatitis B virus infection. We report a child with acute hepatitis A in

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Jarari, Abdalla M., Abdelaziz MA AlFaydi, Nouh MH Aljarari, Saeid Omar Al Soaeiti, Ibtisam Cheith Kaziri, and Dhastagir Sultan Sheriff. "BIOCHEMICAL STUDIES RELATED TO ACUTE CHOLECYSTITIS IN LIBYAN SUBJECTS." International Journal of Research -GRANTHAALAYAH 8, no. 8 (2020): 226–32. http://dx.doi.org/10.29121/granthaalayah.v8.i8.2020.1005.

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Acute cholecystitis and cholelithiasis are one of common health problems of Libyans. [1] Acute cholecystitis or bile gallbladder stones are one of the major surgical problems in the Libyan population and account for many hospital admissions and surgical interventions. This study was done to estimate causes and risk factors of AC among general population of Benghazi city in Libya. Reflux of pancreatic secretions into the biliary duct due to a defect in motility of gallbladder or biliary tree or spastic episodes of Sphincter Oddi may cause injury to gallbladder mucosa and biliary tract which may

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BATRA, POONAM. "Synergy of gut microbiome and bile acids in inducing cholelithiasis." Journal of Advanced Scientific Research 15, no. 08 (2024): 1–9. http://dx.doi.org/10.55218/jasr.2024150801.

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Gallstones have remained an expensive and crippling social problem in public health. The pathophysiology of cholelithiasis is not well understood and involves several variables. Even though, the risk factors for gallstones and other metabolic syndrome are considered to be similar but there is a long list of risk factors associated with lithogenecity such as age, parity and obesity. In addition to all this, intricate relationships between the microecology of the gastrointestinal tract and lithogenesis has been highlighted in this context.The gut microbiome and metabolism of bile acids are deepl

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Haal, Sylke, Maimoena S. S. Guman, Sjoerd Bruin, et al. "Risk Factors for Symptomatic Gallstone Disease and Gallstone Formation After Bariatric Surgery." Obesity Surgery 32, no. 4 (2022): 1270–78. http://dx.doi.org/10.1007/s11695-022-05947-8.

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Abstract Purpose Patients who undergo bariatric surgery are at risk for developing cholesterol gallstones. We aimed to identify risk factors that are associated with symptomatic gallstone disease and gallstone formation after bariatric surgery. Materials and Methods We included participants of the UPGRADE trial, a multicenter randomized placebo-controlled trial on the prevention of symptomatic gallstone disease with ursodeoxycholic acid (UDCA) after bariatric surgery. The association between patient characteristics and symptomatic gallstone disease, and gallstone formation was evaluated using

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Mahdi, Sahar Ahmed, and Israa Jaafar. "Gallbladder diseases detected by ultrasound and correlated risk factors." Romanian Journal of Medical Practice 19, no. 2 (2024): 105–9. http://dx.doi.org/10.37897/rjmp.2024.2.1.

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Background. Gallbladder diseases are relatively common, most of which are asymptomatic, others may be presented with right hypochondriac pain. Obesity, metabolic syndrome, long-term fasting, rapid weight reduction, bariatric surgery and drugs are associated with bile stasis and hence participate in gallstone formation. The study aimed to determine the variety of gall bladder disease detected by ultrasound in Iraqi patients. Methods. This study involved a randomly selected sample of 100 men and 100 women who attended the ultrasound clinic at Emamein Kadhimein Medical City for abdominal ultrason

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Almobarak, Ahmed Omer, Ayat Jervase, Aza Abdelrahman Fadl, et al. "The prevalence of diabetes and metabolic syndrome and associated risk factors in Sudanese individuals with gallstones: a cross sectional survey." Translational Gastroenterology and Hepatology 5 (April 2020): 15. http://dx.doi.org/10.21037/tgh.2019.10.09.

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Rahman, Md Maruf Ur, Mohammad Nayem, Santwana Saha, Wazeda Begum, Tanzida Islam, and Md Motiar Rahman. "Pattern of Lipid Profile in Patients with Cholelithiasis." Journal of Dhaka National Medical College & Hospital 22, no. 1 (2016): 45–49. https://doi.org/10.3329/jdnmch.v22i1.77978.

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Background: Cholelithiasis is one of the most common surgical problem and gastrointestinal diseases throughout the world but its pathogenesis remains unclear. Lipid in the blood play a key role in the aetiology of cholelithiasis. Especially in cholesterol gallstones formation blood lipids are altered which is suggestive of metabolic syndrome. Multiple studies have shown that there is an association between gallstones and abnormal lipids. There is no previous study to explore the pattern of lipid profile in patients with cholelithiasis in Bangladesh. The aim of this study was to evaluate the pa

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Ahmed, Mohamed H., Salma Barakat, and Ahmed O. Almobarak. "The association between renal stone disease and cholesterol gallstones: the easy to believe and not hard to retrieve theory of the metabolic syndrome." Renal Failure 36, no. 6 (2014): 957–62. http://dx.doi.org/10.3109/0886022x.2014.900424.

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Xu, Fusheng, Ruimin Chen, Chengcheng Zhang, et al. "Cholecystectomy Significantly Alters Gut Microbiota Homeostasis and Metabolic Profiles: A Cross-Sectional Study." Nutrients 15, no. 20 (2023): 4399. http://dx.doi.org/10.3390/nu15204399.

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Cholecystectomy (CCE) is a standard clinical treatment for conditions like gallstones and cholecystitis. However, its link to post-CCE syndrome, colorectal cancer, and nonalcoholic fatty liver disease has raised concerns. Additionally, studies have demonstrated the disruptive effects of CCE on gut microbiota homeostasis and bile acid (BA) metabolism. Considering the role of gut microbiota in regulating host metabolic and immune pathways, the use of dietary and probiotic intervention strategies to maintain a stable gut ecosystem after CCE could potentially reduce associated disease risks. Inter

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Tamer, Funda, Osmanege Atliya, Muhterem Polat, and Esra Adisen. "Hepatic Steatosis is the Most Common Finding in Abdominal Ultrasonography Performed in Patients with Psoriasis before Biological Agent Treatment." Romanian Journal of Military Medicine 127, no. 3 (2024): 237–42. http://dx.doi.org/10.55453/rjmm.2024.127.3.9.

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Psoriasis has been associated with metabolic syndrome and nonalcoholic fatty liver disease. We wanted to investigate the abdominal ultrasonography results of psoriasis patients before biological agent treatment. Between April 2019 and February 2022, abdominal ultrasonography results of psoriasis patients which were performed before biological agent treatment were reviewed retrospectively. This study included 90 patients, 45 females, and 45 males with a mean age of 48.91±13.43 years. The most common ultrasonography finding was increased echogenicity of the liver parenchyma due to steatosis (58.

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A.N., Aripov, Aripov O.A., Akhunjanova L.L., Karimov Sh.B., Muhammadjonov B.B., and Khudoerova Z.S. "The Main Causes of the Development of Diseases of the Biliary System in Children, Their Importance and Relevance in Medicine." International Journal of Health & Medical Research 01, no. 05 (2022): 54–58. https://doi.org/10.5281/zenodo.7440420.

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The presented analysis presents the results of a brief review of the literature devoted to the analysis of the occurrence, development and diagnosis of diseases of the hepatobiliary system in children, as well as achievements and shortcomings in treatment. The conducted analyses have shown that today the prevalence and development of obesity worldwide, especially in young children, is increasing every day, and the development of obesity in these children and adolescents is the main modifiable risk factors in the pathogenesis of pathologies of the liver and biliary tract. Based on the above inf

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Carlson, G. L. "Surgical management of intestinal failure." Proceedings of the Nutrition Society 62, no. 3 (2003): 711–18. http://dx.doi.org/10.1079/pns2003287.

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Surgery plays a key role in the management of both acute and, less frequently, chronic intestinal failure. Acute intestinal failure frequently requires surgical treatment when it arises as a consequence of intestinal fistulation or obstruction. In specialised clinical practice approximately 50% of acute intestinal failure is associated with intestinal fistulas and in approximately 50% of patients, this condition arises as part of the natural history or complicating treatment for Crohn's disease. A considerable proportion of such patients have abdominal infection and present complex nutritional

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Li, Chao, Yunlun Li, and Zhibo Gai. "Bile Acids and Farnesoid X Receptor: Novel Target for the Treatment of Diabetic Cardiomyopathy." Current Protein & Peptide Science 20, no. 10 (2019): 976–83. http://dx.doi.org/10.2174/1389203720666190726152847.

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Diabetes mellitus (DM) has become an increasingly common disease with high disability and mortality rates. Diabetes complications are the main cause of diabetes death and about 50% of diabetic patients died from heart disease in developed countries reported by World Health Organization. Diabetic cardiomyopathy (DCM) has been considered as a high incidence and serious complication of DM and plays a key role in the incidence and development of diabetes related heart failure. Metabolism dysregulation is regarded as an important and earlier factor occurred in the pathogenesis of DCM. Insulin resis

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Uspenskiy, Yu P., Yu A. Fominykh, K. N. Nadzhafova, A. V. Vovk, and A. V. Koshcheev. "Pathogenetic aspects of the development of cholelithiasis in patients with metabolic syndrome." Terapevticheskii arkhiv 93, no. 2 (2021): 209–14. http://dx.doi.org/10.26442/00403660.2021.02.200616.

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Nowadays there is a steady tendency to increase the number of patients with gallstone disease and metabolic syndrome. Increasingly, gallstone disease is called a non-canonical cluster of metabolic syndrome, because the main components of metabolic syndrome are also modifiable risk factors for gallstone disease. This article discusses the pathogenetic parallels in the development of gallstone disease and metabolic syndrome - insulin resistance and hormones of adipose tissue, lipid metabolism disorders, immune factors and the cytokine system. There are described possible effects of cholecystecto

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Alamsyah, Agus, M. Kamali Zaman, and Winda Septiani. "Determinants of Adult Obesity in the Working Area of the Simpang Tiga Community Health Center Pekanbaru City." Jurnal Kesehatan Komunitas 5, no. 1 (2019): 23–28. http://dx.doi.org/10.25311/keskom.vol5.iss1.355.

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Obese is a overweight as a result of plutonium body fat excessive. Based on the data from health department the city of pekanbaru 2016 the proportion of the incident obesity was highest for puskesmas simpang three of which was 2.1 % per 19.029 population. Based on preliminary survey, than 20 respondents there were as many as five people ( 25 % ) suffering from obesity. Obesity have an impact on the emergence of various degenerative diseases among others, metabolic syndrome atherosclerosis, of cardiovascular diseases, diabetes, gallstones, disturbance of function pulmonic, hypertension and disl

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Chen, Li-Ying. "Metabolic syndrome and gallstone disease." World Journal of Gastroenterology 18, no. 31 (2012): 4215. http://dx.doi.org/10.3748/wjg.v18.i31.4215.

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Potapova, E. A., L. A. Kharitonova, and Yu E. Milova. "The state of carbohydrate metabolism in children with gallstone disease." Experimental and Clinical Gastroenterology 1, no. 1 (2021): 118–26. http://dx.doi.org/10.31146/1682-8658-ecg-185-1-118-126.

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Cholelithiasis (cholelithiasis) has become increasingly common in childhood. Currently, the features of the clinical course have been studied, the criteria for the diagnosis and prevention of cholelithiasis in children have been worked out. However, the features of metabolic disorders are still not studied, among which not the least role in the genesis of the formation of gallstones is played not only by the exchange of lipids, but also carbohydrates.The main role in the regulation of carbohydrate metabolism is played by insulin. The process of production of insulin in the body in the blood se

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Pulatboevich, Raximov Anvar, Ismailov O’ktam Safaevich, and Batirov Davronbek Yusupovich. "The Role Of rs1799883 Polymorphism Of The FABP2 Gene In The Pathogenesis Of Nosological Syntropy Of Gallstone Disease And Metabolic Syndrome." American Journal of Medical Sciences and Pharmaceutical Research 03, no. 06 (2021): 46–51. http://dx.doi.org/10.37547/tajmspr/volume03issue06-07.

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Objective: to study the role of the rs1799883 polymorphism of the FABP2 gene in the pathogenesis of gallstone disease in combination with MS. Material and methods. Molecular genetic studies were carried out in the Department of Molecular Medicine and Cell Technologies of the RSNPMC Hematology. The analysis of the associations of the rs1799883 polymorphisms of the FABP2 gene was carried out using a case-control model. The main group consisted of 118 patients with cholelithiasis in combination with MS living in the Khorezm region. Results: As a result of our research, we identified a significant

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Dr., Prutha Javalekar. "Comparison of Apache II And CT Scoring System In Predicting Early Outcome of Acute Pancreatitis." International Journal of Medical and Pharmaceutical Research 4, no. 4 (2023): 267–73. https://doi.org/10.5281/zenodo.8276285.

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Acute pancreatitis (AP) is a common and frequent inflammatory disorder of the pancreas with variable involvement of other regional tissues or remote organ systems. Early diagnosis and precise staging of disease severity are important goals in the initial evaluation and management of AP.APACHE II is the most accurate predictor of mortality, CTSI is a good predictor of bothmortality and AP severity, therefore, we compared APACHE II and CT scoring system in predicting early outcome of AP.Patient’s demographic and clinical data/Laboratory /Radiological diagnosis of Acute pancreatitis were an

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Svistunov, Andrey A., Miсhail A. Osadchuk, Natalia V. Kireeva, and Alexey M. Osadchuk. "Gallstone disease as a clinical marker of metabolic syndrome." Obesity and metabolism 15, no. 3 (2018): 3–8. http://dx.doi.org/10.14341/omet9553.

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The prevalence of cholelithiasis, its close pathogenetic connection with metabolic syndrome, high frequency of surgical intervention, significant economic losses put forward this comorbid pathology in a number of leading problems of modern clinical medicine. The factors associated with the metabolic syndrome not only increase the risk of developing cholelithiasis, but also form the basis of non-drug and drug therapy. Metabolic syndrome often determines the occurrence of three common and potentially life-threatening complications of cholelithiasis: acute cholecystitis, acute cholangitis and bil

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Maryam, Mohammed Ali Kareem, Abdulabbas Shraida Amjed, and Salah Razzaq Maha. "Assessment of Nurses' Knowledge Regarding Management of Patient's with Cholelithiasis Disease." International Journal of Current Science Research and Review 05, no. 06 (2022): 1942–47. https://doi.org/10.5281/zenodo.6637016.

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<strong>ABSTRACT: </strong>Cholelithiasis affects approximately 15% of the US population. Rising trends in obesity and metabolic syndrome have contributed to an increase in diagnosis of cholelithiasis. There are several risk factors for cholelithiasis, both modifiable and non modifiable. Women are more likely to experience cholelithiasis than are men. Pregnancy, increasing parity, and obesity during pregnancy further increase the risk that a woman will develop cholelithiasis. The classic presentation of persons experiencing cholelithiasis, specifically when gallstones obstruct the common bile

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Raj, Kumar Paliwal, and Mangal M.M. "The Association between Gallstone Disease & Metabolic Syndrome – A Prospective Observational Study." International Journal of Pharmaceutical and Clinical Research 15, no. 11 (2023): 795–99. https://doi.org/10.5281/zenodo.11221486.

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Background – Gall stone disease a common clinical condition ,mostly affecting the females. Its incidence is increasing in the recent times , owing to various risk factors.Previous literature have reported metabolic syndrome to be present in patients diagnosed with gall stone disease. Aims & Objectives- To assess the association between the presence of gallstone disease and metabolic Syndrome. Material & Methods- This prospective, observational study recruited patients (n=60, age range 20-65 yrs) having cholelithiasis who were admitted in the Department of Surgery , of our tertiar

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Akhmedov, V. A., and O. V. Gaus. "Modern views on development mechanisms and tactics for treatment of patients with gallbladder disease associated with metabolic syndrome." Medical alphabet 2, no. 13 (2019): 52–56. http://dx.doi.org/10.33667/2078-5631-2019-2-13(388)-52-56.

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The high prevalence of metabolic syndrome in population has led to the cholelithiasis is important problem of modern health care along with coronary heart disease, arterial hypertension and diabetes. The main role in the formation of gallbladder pathology in patients with metabolic syndrome belongs to insulin resistance, atherogenic dyslipidemia, and non‑alcoholic fatty liver disease. Тhe prescription of ursodeoxycholic acid is pathogenetically justified. This article presents modern views on the mechanisms formation of gallstone disease in the conditions of metabolic disorders and management

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Méndez-Sánchez, Nahum. "Metabolic syndrome as a risk factor for gallstone disease." World Journal of Gastroenterology 11, no. 11 (2005): 1653. http://dx.doi.org/10.3748/wjg.v11.i11.1653.

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Ng, Ooi Chuan, Husna Rosleli, and Jo-An Ng. "POST-COVID-19 CHRONIC FATIGUE SYNDROME WITH ACUTE PANCREATITIS AND TRANSIENT HYPERZINCEMIA." Journal of the ASEAN Federation of Endocrine Societies 40, S1 (2025): 12–13. https://doi.org/10.15605/jafes.040.s1.016.

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INTRODUCTION/BACKGROUNDChronic fatigue syndrome (CFS) often follows viral infections, including COVID-19. Long COVID is increasingly recognized as a cause of post-viral fatigue. While rare, hyperzincaemia has been linked to acute pancreatitis. This case explores the interplay between post-viral fatigue, metabolic disturbances, autonomic dysfunction, and transient hyperzincaemia in acute pancreatitis. CASEA 61-year-old male with hypertension, benign prostatic hyperplasia, hepatosteatosis, and gallstone-induced acute pancreatitis presented with persistent fatigue post-COVID-19. Clinical evaluati

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Mariana, Partida Rodríguez, Hernández Ortiz Hugo, Ramírez Mejía Lucero, Hernández Ortiz Marisol, and Castillo Aguilar Lizbeth. "Clinical Considerations in Specialized Nutrition in Critically III Patients." International Journal Of Medical Science And Clinical Research Studies 02, no. 10 (2022): 1163–65. https://doi.org/10.5281/zenodo.7260608.

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Specialized nutrition support (SNS) is required when oral intake is either limited or not possible for a prolonged period of time. Common indications for SNS include patients in critical care, those with dysphagia, unconscious patients who cannot be fed, severely malnourished patients, and those with intestinal malabsorption. The two forms of SNS are enteral nutrition and parenteral nutrition. Enteral feeding is always preferred whenever possible, but parenteral feeding may be instituted if the patient has a nonfunctional GI tract (e.g., gastroschisis, short bowel syndromes), and/or if enteral

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Sahla, Sellami, Ammar Saloua, Hsairi Manel, et al. "Metabolic Syndrome in the Development of Gallstone Disease in Children." Metabolism 116 (March 2021): 154564. http://dx.doi.org/10.1016/j.metabol.2020.154564.

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