Academic literature on the topic 'Metabolomics and trascriptomics analysis'

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Dissertations / Theses on the topic "Metabolomics and trascriptomics analysis"

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GUARNERIO, Chiara Francesca. "Effects of enod40 overexpression in non legume plants." Doctoral thesis, Università degli Studi di Verona, 2010. http://hdl.handle.net/11562/343215.

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Il gene ENOD40 è una nodulina precoce ed è indotto durante i primi stadi di formazione del nodulo radicale in risposta alle interazioni tra le leguminose ed i batteri simbionti del genere Rhizobia. Omologhi del gene ENOD40 sono stati identificati in diverse specie e la sua espressione, non unicamente correlata alla formazione del nodulo, è stata osservata in tessuti giovani e meristematici. Una caratteristica che accomuna i geni ENOD40 è l’assenza di un lunga open reading frame (ORF); al contrario, molte piccole ORF sono generalmente presenti nei trascritti. Il gene contiene due regioni alt
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Yet, Idil. "Integrated epigenomics and metabolomics analysis in twins." Thesis, King's College London (University of London), 2016. https://kclpure.kcl.ac.uk/portal/en/theses/integrated-epigenomics-and-metabolomics-analysis-in-twins(4d0fb76b-cc2b-4e31-8950-a7ffb5b91363).html.

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Epigenetics and metabolomics are rapidly growing areas of research, in part due to recent advances in technology that have allowed for a wide coverage of the human genome. Metabolites are small compounds present in cell and body fluids, and are involved in biochemical processes of the cell. Quantitative trait loci associated with levels of individual metabolites (mQTLs) have been identified from numerous metabolome GWAS. Here, I analysed metabolite levels in twins with the aim of identifying genetic variants that influence metabolomic traits (mQTLs) using two different metabolomics platforms,
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Muhamad, Ali Howbeer. "Metabolomics investigation of microbial cell factories." Thesis, University of Manchester, 2015. https://www.research.manchester.ac.uk/portal/en/theses/metabolomics-investigation-of-microbial-cell-factories(2e2f5f58-d38a-4c77-966b-56ce92aec619).html.

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The stream of new technological advancements and their integration into the field of microbiology have contributed significantly towards our understanding of life in the micro-scale world, making the fields of microbiology and biotechnology shine like never before. Since 1980, the recombinant protein-based therapeutics industry has become one of the fastest growing sectors in the biopharmaceutical market. Nearly 30% of commercially available recombinant proteins are produced in Escherichia coli, making this species one of the most commonly used bacterial expression systems for the production o
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Klünder, Christina. "Metabolomics for toxicity analysis using the chlorophyte Scenedesmus vacuolatus /." Leipzig [u.a.], 2009. http://www.ufz.de/data/ufzdiss_2_2009_9947.pdf.

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Gloaguen, Yoann. "Supporting analysis, visualisation and biological interpretation of metabolomics datasets." Thesis, University of Glasgow, 2017. http://theses.gla.ac.uk/8433/.

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Over the past decades, the emerging omics technologies have enabled scientists to take a step further in the investigation of biological systems. From food safety to stratified medicine, omics technologies are now an essential and powerful means to study biological processes. Omics technologies are however at different stages of maturity, and the most recent field of the omics family, metabolomics, is still in its infancy. Metabolomics attempts to catalogue, characterise and quantify all small molecules constitutive of a biological system. Liquid Chromatography - Mass Spectrometry (LCMS) is no
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Abdelrazig, Salah M. A. "Mass spectrometry for high-throughput metabolomics analysis of urine." Thesis, University of Nottingham, 2015. http://eprints.nottingham.ac.uk/30600/.

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Direct electrospray ionisation-mass spectrometry (direct ESI-MS), by omitting the chromatographic step, has great potential for application as a high-throughput approach for untargeted urine metabolomics analysis compared to liquid chromatography-mass spectrometry (LC-MS). The rapid development and technical innovations revealed in the field of ambient ionisation MS such as nanoelectrospray ionisation (nanoESI) chip-based infusion and liquid extraction surface analysis mass spectrometry (LESA-MS) suggest that they might be suitable for high-throughput metabolomics analysis. In this thesis, LC-
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Beisken, Stephan Andreas. "Informatics for tandem mass spectrometry-based metabolomics." Thesis, University of Cambridge, 2014. https://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.708325.

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Duffy, Kate I. "Application of metabolomics to the analysis of ancient organic residues." Thesis, University of Birmingham, 2015. http://etheses.bham.ac.uk//id/eprint/5670/.

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The grape is arguably one of the oldest cultivated products in human history and the analysis of its main product, wine, reveals clues to trade and associations of previous civilizations. In ancient times, wine was stored in clay amphorae, which, if not properly sealed with resin or pitch allowed the wine to wick into clay matrices, dry, and polymerize producing insoluble, intractable materials that may remain within the matrix for several thousand years. Presently, identification of wine residue is based upon the extraction of these polymeric materials from the ceramic matrix and analyzing/id
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Daub, Carsten O. "Analysis of integrated transcriptomics and metabolomics data a systems biology approach /." [S.l. : s.n.], 2004. http://pub.ub.uni-potsdam.de/2004/0025/daub.pdf.

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Daub, Carsten Oliver. "Analysis of integrated transcriptomics and metabolomics data : a systems biology approach." Phd thesis, Universität Potsdam, 2004. http://opus.kobv.de/ubp/volltexte/2005/138/.

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Moderne Hochdurchsatzmethoden erlauben die Messung einer Vielzahl von komplementären Daten und implizieren die Existenz von regulativen Netzwerken auf einem systembiologischen Niveau. Ein üblicher Ansatz zur Rekonstruktion solcher Netzwerke stellt die Clusteranalyse dar, die auf einem Ähnlichkeitsmaß beruht.<br /> Wir verwenden das informationstheoretische Konzept der wechselseitigen Information, das ursprünglich für diskrete Daten definiert ist, als Ähnlichkeitsmaß und schlagen eine Erweiterung eines für gewöhnlich für die Anwendung auf kontinuierliche biologische Daten verwendeten Algorithmu
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