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Relevant bibliographies by topics / Metameric pattern; Presomitic mesoderm; Somites / Journal articles

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Journal articles on the topic 'Metameric pattern; Presomitic mesoderm; Somites'

Author: Grafiati

Published: 4 June 2021

Last updated: 7 February 2022

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1

Takke, C., and J. A. Campos-Ortega. "her1, a zebrafish pair-rule like gene, acts downstream of notch signalling to control somite development." Development 126, no. 13 (1999): 3005–14. http://dx.doi.org/10.1242/dev.126.13.3005.

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During vertebrate embryonic development, the paraxial mesoderm becomes subdivided into metameric units known as somites. In the zebrafish embryo, genes encoding homologues of the proteins of the Drosophila Notch signalling pathway are expressed in the presomitic mesoderm and expression is maintained in a segmental pattern during somitogenesis. This expression pattern suggests a role for these genes during somite development. We misexpressed various zebrafish genes of this group by injecting mRNA into early embryos. RNA encoding a constitutively active form of notch1a (notch1a-intra) and a trun

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2

Tam, P. P. L. "A study on the pattern of prospective somites in the presomitic mesoderm of mouse embryos." Development 92, no. 1 (1986): 269–85. http://dx.doi.org/10.1242/dev.92.1.269.

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Consistently six to seven soniites were formed in explants of presomitic mesoderm of 8·5-day to 11·5-day mouse embryos and this number correlated well with the number of somitomeres previously identified in the same tissue by stereo SEM (Tam, Meier & Jacobson, 1982). During this period of development, the size of the presomitic mesoderm varied up to two-fold but the number of prospective somites remained unchanged. This pattern in the presomitic mesoderm was stable with respect to the number and the position of somites that were formed, the craniocaudal sequence and the rate of segmentatio

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3

POLEZHAEV, A. A. "MATHEMATICAL MODELLING OF THE MECHANISM OF VERTEBRATE SOMITIC SEGMENTATION." Journal of Biological Systems 03, no. 04 (1995): 1041–51. http://dx.doi.org/10.1142/s0218339095000939.

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A mathematical model for the mechanism of periodic pattern formation in the process of somitogenesis is proposed. It is assumed that metameric arrangement first appears before somite formation at the stage of transition of mesodermal into presomitic cells. It is assumed that the transition occurs in a certain phase of the mitotic cycle and that it can be suppressed due to excretion of some transition inhibitor by presomitic cells. The model demonstrates that periodicity can appear as a result of interaction of the wave of somitogenic cell determination with the mitotic cycles of mesodermal cel

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4

Freitas, Catarina, Sofia Rodrigues, Jean-Baptiste Charrier, Marie-Aimée Teillet, and Isabel Palmeirim. "Evidence for medial/lateral specification and positional information within the presomitic mesoderm." Development 128, no. 24 (2001): 5139–47. http://dx.doi.org/10.1242/dev.128.24.5139.

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In the vertebrate embryo, segmentation is built on repetitive structures, named somites, which are formed progressively from the most rostral part of presomitic mesoderm, every 90 minutes in the avian embryo. The discovery of the cyclic expression of several genes, occurring every 90 minutes in each presomitic cell, has shown that there is a molecular clock linked to somitogenesis. We demonstrate that a dynamic expression pattern of the cycling genes is already evident at the level of the prospective presomitic territory. The analysis of this expression pattern, correlated with a quail/chick f

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5

Kim, Woong, Takaaki Matsui, Masataka Yamao, et al. "The period of the somite segmentation clock is sensitive to Notch activity." Molecular Biology of the Cell 22, no. 18 (2011): 3541–49. http://dx.doi.org/10.1091/mbc.e11-02-0139.

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The number of vertebrae is defined strictly for a given species and depends on the number of somites, which are the earliest metameric structures that form in development. Somites are formed by sequential segmentation. The periodicity of somite segmentation is orchestrated by the synchronous oscillation of gene expression in the presomitic mesoderm (PSM), termed the “somite segmentation clock,” in which Notch signaling plays a crucial role. Here we show that the clock period is sensitive to Notch activity, which is fine-tuned by its feedback regulator, Notch-regulated ankyrin repeat protein (N

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6

Orr-Urtreger, A., M. T. Bedford, M. S. Do, L. Eisenbach, and P. Lonai. "Developmental expression of the alpha receptor for platelet-derived growth factor, which is deleted in the embryonic lethal Patch mutation." Development 115, no. 1 (1992): 289–303. http://dx.doi.org/10.1242/dev.115.1.289.

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The alpha receptor of PDGF (Pdgfra) is expressed in primitive endoderm and mesoderm derivatives throughout embryogenesis. In the early primitive streak stage the gene is transcribed in the visceral and parietal endoderm. Later it is expressed in the presomitic mesoderm, yolk sac and amnion. During somitogenesis its transcription localizes to the heart and the somites. Subsequently, it is transcribed in the dermatome, the sclerotome, the developing limb and in various mesenchymal tissues of visceral organs. Its wild-type expression pattern correlates well with the phenotype of homozygous mutant

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7

Nieto, M. A., P. Gilardi-Hebenstreit, P. Charnay, and D. G. Wilkinson. "A receptor protein tyrosine kinase implicated in the segmental patterning of the hindbrain and mesoderm." Development 116, no. 4 (1992): 1137–50. http://dx.doi.org/10.1242/dev.116.4.1137.

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Pattern formation in the hindbrain and paraxial mesoderm of vertebrates occurs by the formation of a series of repeated segments. These processes of segmentation appear different at the morphological level, since hindbrain segments, the rhombomeres, form by the subdivision of the neural epithelium into compartments, whereas the mesodermal somites form by the sequential aggregation of mesenchymal cells into epithelial balls. Previous studies have implicated genes encoding transcription factors in the development of hindbrain segments, but nothing is known of genes involved in the formation of s

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8

Stern, Claudio D., Scott E. Fraser, Roger J. Keynes, and Dennis R. N. Primmett. "A cell lineage analysis of segmentation in the chick embryo." Development 104, Supplement (1988): 231–44. http://dx.doi.org/10.1242/dev.104.supplement.231.

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We have studied the lineage history of the progenitors of the somite mesoderm and of the neural tube in the chick embryo by injecting single cells with the fluorescent tracer, rhodamine-lysine-dextran. We find that, although single cells within the segmental plate give rise to discrete clones in the somites to which they contribute, neither the somites nor their component parts (sclerotome, dermatome, myotome or their rostral and caudal halves) are `compartments' in the sense defined in insects. Cells in the rostral two thirds or so of the segmental plate contribute only to somite tissue and d

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9

Tam, P. P., and R. S. Beddington. "The formation of mesodermal tissues in the mouse embryo during gastrulation and early organogenesis." Development 99, no. 1 (1987): 109–26. http://dx.doi.org/10.1242/dev.99.1.109.

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Orthotopic grafts of [3H]thymidine-labelled cells have been used to demonstrate differences in the normal fate of tissue located adjacent to and in different regions of the primitive streak of 8th day mouse embryos developing in vitro. The posterior streak produces predominantly extraembryonic mesoderm, while the middle portion gives rise to lateral mesoderm and the anterior region generates mostly paraxial mesoderm, gut and notochord. Embryonic ectoderm adjacent to the anterior part of the streak contributes mainly to paraxial mesoderm and neurectoderm. This pattern of colonization is similar

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10

Goldstein, R. S., and C. Kalcheim. "Determination of epithelial half-somites in skeletal morphogenesis." Development 116, no. 2 (1992): 441–45. http://dx.doi.org/10.1242/dev.116.2.441.

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The segmental body plan of vertebrates arises from the metameric organization of the paraxial mesoderm into somites. Each mesodermal somite is subdivided into at least two distinct domains: rostral and caudal. The segmental pattern of dorsal root ganglia, sympathetic ganglia and nerves is imposed by differential properties of either somitic domain. In the present work, we have extended these studies by investigating the contribution of rostral or caudal-half somites to vertebral development using grafts of multiple somite halves. In both rostral and caudal somitic implants, the grafted mesoder

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11

Sari, Dini Wahyu Kartika, Ryutaro Akiyama, Takaaki Matsui, and Yasumasa Bessho. "LIVE IMAGING OF ERK ACTIVITY STEPWISE PATTERNING DURING SOMITOGENESIS." KnE Life Sciences 2, no. 1 (2015): 363. http://dx.doi.org/10.18502/kls.v2i1.176.

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<p>Periodical segmentation of the anterior extremity of the presomitic mesoderm (PSM) generates metameric structure of somites during vertebrate development. During somite segmentation in zebrafish, msep determines a future somite boundary at position B-2 within the PSM. However, heat shock experiments suggest that an earlier future of somite boundary exists at B-5, but the molecular signature of this boundary remains unidentified. Our recent study demonstrated that fibroblast growth factor (FGF) gradient is converted into an ON-OFF boundary of downstream Erk activity, which corresponds

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12

Candia, A. F., J. Hu, J. Crosby, et al. "Mox-1 and Mox-2 define a novel homeobox gene subfamily and are differentially expressed during early mesodermal patterning in mouse embryos." Development 116, no. 4 (1992): 1123–36. http://dx.doi.org/10.1242/dev.116.4.1123.

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We have isolated two mouse genes, Mox-1 and Mox-2 that, by sequence, genomic structure and expression pattern, define a novel homeobox gene family probably involved in mesodermal regionalization and somitic differentiation. Mox-1 is genetically linked to the keratin and Hox-2 genes of chromosome 11, while Mox-2 maps to chromosome 12. At primitive streak stages (approximately 7.0 days post coitum), Mox-1 is expressed in mesoderm lying posterior of the future primordial head and heart. It is not expressed in neural tissue, ectoderm, or endoderm. Mox-1 expression may therefore define an extensive

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13

Muller, M., E. Weizsacker, and J. A. Campos-Ortega. "Expression domains of a zebrafish homologue of the Drosophila pair-rule gene hairy correspond to primordia of alternating somites." Development 122, no. 7 (1996): 2071–78. http://dx.doi.org/10.1242/dev.122.7.2071.

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her1 is a zebrafish cDNA encoding a bHLH protein with all features characteristic of members of the Drosophila HAIRY-E(SPL) family. During late gastrulation stages, her1 is expressed in the epibolic margin and in two distinct transverse bands of hypoblastic cells behind the epibolic front. After completion of epiboly, this pattern persists essentially unchanged through postgastrulation stages; the marginal domain is incorporated in the tail bud and, depending on the time point, either two or three paired bands of expressing cells are present within the paraxial presomitic mesoderm separated by

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14

Park, Sean, Young Jae Lee, Ho-Jae Lee, et al. "B-Cell Translocation Gene 2 (Btg2) Regulates Vertebral Patterning by Modulating Bone Morphogenetic Protein/Smad Signaling." Molecular and Cellular Biology 24, no. 23 (2004): 10256–62. http://dx.doi.org/10.1128/mcb.24.23.10256-10262.2004.

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ABSTRACT Btg2 is a primary p53 transcriptional target gene which may function as a coactivator-corepressor and/or an adaptor molecule that modulates the activities of its interacting proteins. We have generated Btg2-null mice to elucidate the in vivo function of Btg2. Btg2-null mice are viable and fertile but exhibit posterior homeotic transformations of the axial vertebrae in a dose-dependent manner. Consistent with its role in vertebral patterning, Btg2 is expressed in the presomitic mesoderm, tail bud, and somites during somitogenesis. We further provide biochemical evidence that Btg2 inter

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15

Baker, Ruth E., Santiago Schnell, and Philip K. Maini. "Formation of Vertebral Precursors: Past Models and Future Predictions." Journal of Theoretical Medicine 5, no. 1 (2003): 23–35. http://dx.doi.org/10.1080/10273660310001628365.

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Disruption of normal vertebral development results from abnormal formation and segmentation of the vertebral precursors, called somites. Somitogenesis, the sequential formation of a periodic pattern along the antero-posterior axis of vertebrate embryos, is one of the most obvious examples of the segmental patterning processes that take place during embryogenesis and also one of the major unresolved events in developmental biology. We review the most popular models of somite formation: Cooke and Zeeman's clock and wavefront model, Meinhardt's reaction-diffusion model and the cell cycle model of

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16

Childs, Sarah, Jau-Nian Chen, Deborah M. Garrity, and Mark C. Fishman. "Patterning of angiogenesis in the zebrafish embryo." Development 129, no. 4 (2002): 973–82. http://dx.doi.org/10.1242/dev.129.4.973.

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Little is known about how vascular patterns are generated in the embryo. The vasculature of the zebrafish trunk has an extremely regular pattern. One intersegmental vessel (ISV) sprouts from the aorta, runs between each pair of somites, and connects to the dorsal longitudinal anastomotic vessel (DLAV). We now define the cellular origins, migratory paths and cell fates that generate these metameric vessels of the trunk. Additionally, by a genetic screen we define one gene, out of bounds (obd), that constrains this angiogenic growth to a specific path. We have performed lineage analysis, using l

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17

Zhao, Wei, Masayuki Oginuma, Rieko Ajima, Makoto Kiso, Akemi Okubo, and Yumiko Saga. "Ripply2 recruits proteasome complex for Tbx6 degradation to define segment border during murine somitogenesis." eLife 7 (May 15, 2018). http://dx.doi.org/10.7554/elife.33068.

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The metameric structure in vertebrates is based on the periodic formation of somites from the anterior end of the presomitic mesoderm (PSM). The segmentation boundary is defined by the Tbx6 expression domain, whose anterior limit is determined by Tbx6 protein destabilization via Ripply2. However, the molecular mechanism of this process is poorly understood. Here, we show that Ripply2 directly binds to Tbx6 in cultured cells without changing the stability of Tbx6, indicating an unknown mechanism for Tbx6 degradation in vivo. We succeeded in reproducing in vivo events using a mouse ES induction

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