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Journal articles on the topic 'Metaphysis of tibia'

Author: Grafiati

Published: 4 June 2021

Last updated: 2 February 2022

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1

Nagamine, Ryuji, Makoto Kawasaki, Kang-Il Kim, Akinori Sakai, and Toru Suguro. "The posterior tibial slope is mainly created by the posterior rotation of the tibial condyles." Journal of Orthopaedic Surgery 28, no. 3 (2020): 230949902097558. http://dx.doi.org/10.1177/2309499020975580.

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Purpose: Constitutional varus in the coronal plane is formed based on the Hueter-Volkmann’s law. The varus deformity occurs at the proximal metaphysis of the tibia and the tibial condyle rotates medially. In the sagittal plane, we hypothesized that the posterior slope angle of the tibial articular surface may also occur at the proximal metaphysis and the tibial condyle rotates posteriorly. The purpose of this study was to verify the hypothesis. Methods: A total of 208 patients who underwent TKA had lateral view proximal tibia digital radiograph on which seven parameters were analyzed. The post

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Noonan, Timothy, Michael Pinzur, Odysseas Paxinos, Robert Havey, and Avinash Patwardhin. "Tibiotalocalcaneal Arthrodesis With a Retrograde Intramedullary Nail: A Biomechanical Analysis of the Effect of Nail Length." Foot & Ankle International 26, no. 4 (2005): 304–8. http://dx.doi.org/10.1177/107110070502600406.

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Background: Fatigue fractures of the tibia have been observed at the level of the proximal end of the nail after successful tibiocalcaneal arthrodesis with a retrograde intramedullary device. Materials: To study the effect of nail length, five matched pairs of cadaver tibiae were instrumented with strain gauges and potted in methyl-methacrylate from a level 3 cm proximal to the distal medial malleolus to simulate a successful tibiocalcaneal arthrodesis. A standard length (15 cm) ankle arthrodesis nail and an identical longer device terminating in the proximal tibial metaphysis were inserted in

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Thirunarayanan, Vasudevan, Dhurvas R. Ramprasath, Ramachandran Amarnath, and Velmani Arun. "An Observation of Posterior Tibial Slope and Metaphysio-diaphyseal Angle in Indian Population." Journal of Orthopedics and Joint Surgery 2, no. 2 (2020): 52–56. http://dx.doi.org/10.5005/jp-journals-10079-1023.

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ABSTRACT Introduction The posterior inclination of the tibial plateau relative to the longitudinal axis of tibia is referred to as the posterior tibial slope (PTS). There is paucity of data regarding PTS in Indian population. Metaphysio-diaphyseal angle (MDA) is the angle between longitudinal axis of tibia and proximal tibial metaphysis, a new entity with a possible clinical significance. This study was performed to determine the mean PTS and mean MDA to study the correlation of PTS and MDA changes with osteoarthritic degeneration in Indian population and to assess the sensitivity and specific

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Tomic, Slavko, Aleksandar Lesic, V. Bumbasirevic, O. Krajcinovic, Nemanja Slavkovic, and Marko Bumbasirevic. "Treatment of gigantocellular tumor of the tibia metaphysis by means of the Ilizarov method: A case study." Acta chirurgica Iugoslavica 52, no. 2 (2005): 131–35. http://dx.doi.org/10.2298/aci0502131t.

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The authors show a 36-year old female patient with a gigantocellular tumor of the distal metaphysis of the left tibia (stage III by Campanacci). A 7.6 cm long distal articular defect of the tibia has been formed by radical segmentary resection. The defect was compensated by the extension of the rest of the tibia; whereas the support function of the limb was provided through tibio-talar arthrodesis. 5.5 years after the surgery, there are no signs of local relapses; the patient walks without any orthopedic aids and works at the same job as prior to the operation.

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5

Ozsoy, S., O. Guzel, and K. Altunatmaz. "Bilateral pes valgus in an Anatolian Sheepdog." Veterinary and Comparative Orthopaedics and Traumatology 20, no. 03 (2007): 241–44. http://dx.doi.org/10.1160/vcot-06-10-0083.

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SummaryA 15-month-old, male, Anatolian Sheepdog weighing 45 kg, was admitted with uneven stance in both hindlegs, a condition it had had since the age of six months. Radiographs of both hindlimbs revealed lateral deviation of 26° in the distal metaphysis of the left tibia and 32° in the distal metaphysis of the right tibia. Corrective osteotomy was used to treat the deformity. Both tibias were aligned with the closed wedge osteotomy and a suitably curved plate was placed on both bones. In the assessment prior to the removal of both plates, it was determined that a valgus deformation of 6° was

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6

Novaretti, João V., Jason J. Shin, Marcio Albers, et al. "Bone Bruise Patterns in Skeletally Immature Patients With Anterior Cruciate Ligament Injury: Shock-Absorbing Function of the Physis." American Journal of Sports Medicine 46, no. 9 (2018): 2128–32. http://dx.doi.org/10.1177/0363546518777247.

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Background: Bone bruises are frequently found on magnetic resonance imaging (MRI) after anterior cruciate ligament (ACL) injury and have been related to the force associated with the trauma. Yet, little is known about the bone bruise distribution pattern of skeletally immature (SI) patients, as the presence of an open physis may play a role in energy dissipation given its unique structure. Purpose: To describe and compare the location and distribution of tibial and femoral bone bruises, observed on MRI, between 2 groups of ACL-injured knees: the first group with an open physis and the second w

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7

Miceli, Ana Lucia Carpi, Livia Costa Pereira, Thiago da Silva Torres, MônicaDiuana Calasans-Maia, and Rafael Seabra Louro. "Mandibular Reconstruction with Lateral Tibial Bone Graft: An Excellent Option for Oral and Maxillofacial Surgery." Craniomaxillofacial Trauma & Reconstruction 10, no. 4 (2017): 292–98. http://dx.doi.org/10.1055/s-0036-1593475.

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Autogenous bone grafts are the gold standard for reconstruction of atrophic jaws, pseudoarthroses, alveolar clefts, orthognathic surgery, mandibular discontinuity, and augmentation of sinus maxillary. Bone graft can be harvested from iliac bone, calvarium, tibial bone, rib, and intraoral bone. Proximal tibia is a common donor site with few reported problems compared with other sites. The aim of this study was to evaluate the use of proximal tibia as a donor area for maxillofacial reconstructions, focusing on quantifying the volume of cancellous graft harvested by a lateral approach and to asse

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8

Hoots, Eric A., and Steve W. Petersen. "Tibial Plateau Leveling Osteotomy and Cranial Closing Wedge Ostectomy in a Cat With Cranial Cruciate Ligament Rupture." Journal of the American Animal Hospital Association 41, no. 6 (2005): 395–99. http://dx.doi.org/10.5326/0410395.

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A 5-year-old domestic shorthair cat was presented for a nonweight-bearing left pelvic-limb lameness. Orthopedic and radiographic examinations revealed a cranial cruciate ligament rupture and deformity of the proximal tibial metaphysis. The deformity of the proximal tibia resulted in an exaggerated tibial plateau angle of approximately 75°. Surgical correction was performed with a combination of tibial plateau leveling osteotomy and cranial closing wedge ostectomy. The procedures resulted in an excellent clinical outcome with immediate return to weight bearing in the operated limb and progressi

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Sheng, Z. F., R. C. Dai, X. P. Wu, L. N. Fang, H. J. Fan, and E. Y. Liao. "Regionally specific compensation for bone loss in the tibial trabeculae of estrogen-deficient rats." Acta Radiologica 48, no. 5 (2007): 531–39. http://dx.doi.org/10.1080/02841850701283761.

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Background: Bone mineral density (BMD) and microstructural variations have been extensively investigated in recent years; however, the compensation for bone loss between different regions is still unclear. Purpose: To fully characterize regional variations in bone mineral density (BMD) as well as the microstructure and dynamic changes of rat tibial trabeculae that occur with bone loss associated with estrogen deficiency. Material and Methods: Female Sprague-Dawley rats were ovariectomized (OVX), sham-operated (sham), or left unoperated (baseline control). The left tibiae were harvested at base

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10

Theisz, Gűnther, Karel Frydrýšek, František Fojtík, et al. "Locking Compression Plate for Distal Tibia Fractures." Applied Mechanics and Materials 827 (February 2016): 359–66. http://dx.doi.org/10.4028/www.scientific.net/amm.827.359.

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This article represents a multidisciplinary approach to biomechanics (engineering + medicine) in the field of distal tibia fractures. The objective of the present study was to carry out a strength and reliability assessment of a medial plate for the treatment of distal tibia fractures. This was performed via numerical modelling (FEM) and experimental methods (compression test and Electronic Speckle Pattern Interferometry – ESPI method). The plate is used for internal fixation in orthopaedics and traumatology. Analyses were performed for non-fused bone with comminuted fracture in the distal met

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Soto-Peñaloza, David, Marco Caneva, José Viña-Almunia, José Martín-de-Llano, David Peñarrocha-Oltra, and Miguel Peñarrocha-Diago. "Bone-Healing Pattern on the Surface of Titanium Implants at Cortical and Marrow Compartments in Two Topographic Sites: an Experimental Study in Rabbits." Materials 12, no. 1 (2018): 85. http://dx.doi.org/10.3390/ma12010085.

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This study evaluates the bone-healing patterns on the surface of titanium implants at the cortical and marrow compartments of bicortically-installed implants in the diaphysis and metaphysis of rabbit tibiae. In 27 New Zealand rabbits, two implants, one for each macro-design and with equal resorbable blasted media (RBM) implant surfaces, were randomly implanted in the diaphysis or metaphysis of each tibia. The flaps were sutured to allow submerged healing. The animals were sacrificed after two, four, or eight weeks, with nine weeks used for the period of healing. Ground sections were prepared a

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Teófilo, Juliana Mazzonetto, Ana Carolina Bernardes Azevedo, Sérgio Olavo Petenusci, Renata Mazaro, and Teresa Lúcia Lamano-Carvalho. "Comparison between two experimental protocols to promote osteoporosis in the maxilla and proximal tibia of female rats." Pesquisa Odontológica Brasileira 17, no. 4 (2003): 302–6. http://dx.doi.org/10.1590/s1517-74912003000400002.

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The effects of two experimental protocols (ovariectomy associated or not with a low calcium diet) used to promote osteoporosis in the rat maxilla and proximal tibia were compared 5 and 11 weeks after surgery. Female Wistar rats were ovariectomized or sham-operated. Half of the ovariectomized rats were fed a low Ca++ diet (ovx*) and the remaining ovariectomized (ovx) and sham animals received a standard chow. At sacrifice, the proximal metaphysis was excised from the tibia and the molars were extracted from the hemi-maxilla. Dry (60°C overnight) and ash (700°C/14 h) weights were measured and th

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Lynch, Maureen E., Russell P. Main, Qian Xu, et al. "Cancellous bone adaptation to tibial compression is not sex dependent in growing mice." Journal of Applied Physiology 109, no. 3 (2010): 685–91. http://dx.doi.org/10.1152/japplphysiol.00210.2010.

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Mechanical loading can be used to increase bone mass and thus attenuate pathological bone loss. Because the skeleton's adaptive response to loading is most robust before adulthood, elucidating sex-specific responses during growth may help maximize peak bone mass. This study investigated the effect of sex on the response to controlled, in vivo mechanical loading in growing mice. Ten-week-old male and female C57Bl/6 mice underwent noninvasive compression of the left tibia. Peak loads of −11.5 N were applied, corresponding to +1,200 με at the tibial midshaft in both sexes. Cancellous bone mass, a

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Cristescu, Ioan, Cristi Angheluta, Florin Safta, et al. "The Outcome of Tricalcium Phosphate Wedges Used in Opening High Tibial Osteotomy." Key Engineering Materials 695 (May 2016): 139–43. http://dx.doi.org/10.4028/www.scientific.net/kem.695.139.

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In the case of patients suffering from medial compartment osteoarthritis of the knee, a high tibial osteotomy is the preferred treatment for preserving the knee articulation and correcting the knee biomechanical axis. Nowadays, the open wedge high tibial osteotomy is the preferred surgical technique for treating patient with varus knee angulation. The procedure consists in creating a medial gap in the proximal tibial metaphysis that is filled with autologus bone graft or bone substitutes. Synthetic bone substitutes made by bioceramics like hydroxyapatite or tricalcium phosphate are becoming mo

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Soniat, M. E., S. Elder, R. McLaughlin, and J. L. Demko. "Axial pull-out strength of 3.5 cortical and 4.0 cancellous bone screws placed in canine proximal tibias using manual and power tapping." Veterinary and Comparative Orthopaedics and Traumatology 21, no. 04 (2008): 323–28. http://dx.doi.org/10.3415/vcot-07-08-0082.

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SummaryAn in vitro experimental cadaveric mechanical testing study was performed using 20 radiographically mature dogs, weighing between 18–33 kg. The aim of the study was to compare the axial pull-out strength of 3.5 mm cortical and 4.0 mm cancellous bone screws inserted in the canine proximal tibia using manual and power tapping techniques. 3.5 cortical and 4.0 cancellous bone screws were inserted in canine cadaver proximal tibiae using a manual or power tapping technique. The screws were extracted using a servohydraulic materials testing machine in order to measure axial pullout strength. A

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Mohler, David Glenn, and David Charles Cunningham. "Adamantinoma Arising in the Distal Fibula Treated with Distal Fibulectomy: A Case Report and Review of the Literature." Foot & Ankle International 18, no. 11 (1997): 746–51. http://dx.doi.org/10.1177/107110079701801112.

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Adamantinoma is a rare primary bone tumor occurring in the mandible and the long tubular bones. The diaphysis of the tibia is the most common site of extragnathic presentation. Fibular involvement is rare and usually has coexisting tibial involvement. Adamantinoma arising in the distal fibular metaphysis has not been previously reported. This is a case of a teenage boy presenting with a cystic lesion of the distal fibula, initially diagnosed and treated as a unicameral bone cyst. Aggressive behavior ultimately led to a diagnosis of adamantinoma. He was treated with distal fibulectomy without s

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Jovanovic, Vesna, Zoran Vukasinovic, Igor Seslija, and Zorica Zivkovic. "Treatment of septic pseudoarthrosis of tibia by Ilizarov method: Case report." Srpski arhiv za celokupno lekarstvo 138, no. 9-10 (2010): 643–46. http://dx.doi.org/10.2298/sarh1010643j.

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Introduction. Septic pseudoarthroses of the tibia represent a relatively frequent complication of open fractures with a large soft tissue damage. They may be localized: in the proximal metaphysis, between the proximal and middle thirds, between middle and distal thirds, in the distal metaphysis. Case Outline. A case of a 52-year-old man with open fracture of the left tibia is presented. He fell from the height of 30 meters. The external fixation according to Mitkovic was performed in another institution. The patient was referred to our hospital nine months after the accident, with clear clinic

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Lukasiewicz, Adam M., Paul S. Bagi, Kristin E. Yu, Vineet Tyagi, and Raymond J. Walls. "Novel Vacuum-Assisted Method for Harvesting Autologous Cancellous Bone Graft and Bone Marrow From the Proximal Tibial Metaphysis." Foot & Ankle Orthopaedics 6, no. 1 (2021): 247301142098190. http://dx.doi.org/10.1177/2473011420981901.

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Background: Autogenous cancellous bone graft and bone marrow aspirate are commonly used in lower extremity fusion procedures to enhance fusion potential, and frequently in revision situations where bone loss and osteolysis may be a feature. The tibial metaphysis is a common donor site for bone graft, with the procedure typically performed using a curette or trephine to harvest the cancellous bone. Some limitations of this technique include suboptimal harvest of the marrow portion in particular, incomplete graft harvest, and loss of graft material during the harvest process. We describe a novel

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Cavolina, Jason M., Glenda L. Evans, Steven A. Harris, Minzhi Zhang, Kim C. Westerlind, and Russell T. Turner. "The Effects of Orbital Spaceflight on Bone Histomorphometry and Messenger Ribonucleic Acid Levels for Bone Matrix Proteins and Skeletal Signaling Peptides in Ovariectomized Growing Rats*." Endocrinology 138, no. 4 (1997): 1567–76. http://dx.doi.org/10.1210/endo.138.4.5040.

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Abstract A 14-day orbital spaceflight was performed using ovariectomized Fisher 344 rats to determine the combined effects of estrogen deficiency and near weightlessness on tibia radial bone growth and cancellous bone turnover. Twelve ovariectomized rats with established cancellous osteopenia were flown aboard the space shuttle Columbia (STS-62). Thirty ovariectomized rats were housed on earth as ground controls: 12 in animal enclosure modules, 12 in vivarium cages, and 6 killed the day of launch for baseline measurements. An additional 18 ovary-intact rats were housed in vivarium cages as gro

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Banu, Jameela, Erika Varela, Ali N. Bahadur, Raheela Soomro, Nishu Kazi, and Gabriel Fernandes. "Inhibition of Bone Loss byCissus quadrangularisin Mice: A Preliminary Report." Journal of Osteoporosis 2012 (2012): 1–10. http://dx.doi.org/10.1155/2012/101206.

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Women drastically loose bone during and after menopause leading to osteoporosis, a disease characterized by low bone mass increasing the risk of fractures with minor trauma. Existing therapies mainly reduce bone resorption, however, all existing drugs have severe side effects. Recently, the focus is to identify alternative medicines that can prevent and treat osteoporosis with minimal or no side effects. We usedCissus quadrangularis(CQ), a medicinal herb, to determine its effects on bone loss after ovariectomy in C57BL/6 mice. Two-month old mice were either sham operated or ovariectomized and

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Skak, Sören V., Tim Toftgård Jensen, and Torben Dam Poulsen. "Fracture of the proximal metaphysis of the tibia in children." Injury 18, no. 3 (1987): 149–56. http://dx.doi.org/10.1016/0020-1383(87)90127-6.

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Sharma, Geetanjali, Mohammad Shorafa, and Gurdeep Hans. "Management of progressive facial asymmetry owing to a rare temporomandibular joint tumour: A case report." Journal of Orthodontics 47, no. 2 (2020): 163–69. http://dx.doi.org/10.1177/1465312520908272.

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Osteochondroma of the condyle is a rare, slow-growing, benign tumour of the temporomandibular joint that can result in facial asymmetry, limited mouth opening, temporomandibular joint dysfunction and malocclusion. The large majority of osteochondromas occur at the distal metaphysis of the femur and the proximal metaphysis of the tibia, whereas only 0.6% of osteochondromas have been reported as occurring in the craniofacial region. We discuss the diagnosis and treatment of a 56-year-old fit and well male patient who presented to the Orthodontic Department at Wexham Park Hospital with a four-yea

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Schlumbohm, Christina, Dana Seidlová-Wuttke, and Eberhard Fuchs. "Effect of ovariectomy on proximal tibia metaphysis and lumbar vertebral body in common marmoset monkeys." Primate Biology 6, no. 2 (2019): 65–73. http://dx.doi.org/10.5194/pb-6-65-2019.

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Abstract. This study aimed to investigate the effect of estrogen withdrawal on bone tissue in adult female marmoset monkeys. In a 1-year follow-up study we used quantitative computer tomography to measure total bone mineral density (BMD) of the proximal tibia and the second-last lumbar vertebral body (L5/L6) before and 1, 3, 6, and 12 months after ovariectomy. Body mass did not significantly change during the 1-year observation period. However, a significant decline of total BMD after ovariectomy was observed in the proximal tibia but not in L5/L6. In addition, regression analysis showed a sig

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Uchiyama, E., K. Yamakoshi, and T. Sasaki. "Measurement of Mechanical Characteristics of Tibial Periosteum and Evaluation of Local Differences." Journal of Biomechanical Engineering 120, no. 1 (1998): 85–91. http://dx.doi.org/10.1115/1.2834311.

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Stress–strain relationships of bovine tibial periosteum, harvested from anterior, medial, lateral, and posterior aspects of tibia, were successfully measured using a newly developed experimental system. Results showed a curvilinear stress–strain pattern having three regions, i.e., toe, almost linear, and rupture regions, which resembled those of biological soft tissues like ligaments, skin, etc. Tensile moduli in the toe region (Ee) and in the linear region (Ec) were obtained by linear regressional analyses. These values and the tensile strength (σt) showed clear local differences. The values

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Yang, Rong-Sen, Tang-Kue Liu, and Shoei-Yn Lin-Shiau. "Local Intraosseous Injection of Staurosporine Increased Bone Formation in Rats." Journal of Musculoskeletal Research 01, no. 01 (1997): 33–39. http://dx.doi.org/10.1142/s0218957797000050.

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The effects of local intraosseous injection of staurosporine on bone formation were investigated in the weaning Sprague-Dawley rats. The left tibia received administration of staurosporine (0.5 pmole/day for 2 weeks) into the metaphysis. The contralateral right tibia received injection with DMSO vehicle and saline was used for the control. Another group of rats which received no injection provided another normal control. The results showed that the body weight gain was decreased by staurosporine, but the tibial length was not affected. Histological examination showed that local injection of st

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Alt, Volker, Peter-J??rgen Meeder, David Seligson, Arno Schad, and Cesar Atienza,. "The Proximal Tibia Metaphysis: A Reliable Donor Site for Bone Grafting?" Clinical Orthopaedics and Related Research 414 (September 2003): 315–21. http://dx.doi.org/10.1097/01.blo.0000079261.91782.df.

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Alkhreisat, Mohammad, M. Al-Maiyah, Jayasree Ramas Ramaskandhan, et al. "Change in Bone Mineral Density after Total Ankle Replacement: Two Year Follow Up." Foot & Ankle Orthopaedics 4, no. 4 (2019): 2473011419S0009. http://dx.doi.org/10.1177/2473011419s00090.

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Category: Ankle, Ankle Arthritis Introduction/Purpose: Bone strength about the components is an important factor in Arthroplasty survival. This importance has been studied in total hip & knee replacement. However, there is paucity of literature Where little has been published regarding the quality of the bone and bone mineral content postoperatively surrounding Ankle Arthroplasty and circumstances surrounding the development of stress fracture. This prospective study used a method to quantify Bone Mineral Density BMD in different regions of the surrounding bones adjacent to tibia and talar

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Iimura, Kaori, Nobuhiro Watanabe, Philip Milliken, et al. "Chronic Electrical Stimulation of the Superior Laryngeal Nerve in the Rat: A Potential Therapeutic Approach for Postmenopausal Osteoporosis." Biomedicines 8, no. 9 (2020): 369. http://dx.doi.org/10.3390/biomedicines8090369.

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Electrical stimulation of myelinated afferent fibers of the superior laryngeal nerve (SLN) facilitates calcitonin secretion from the thyroid gland in anesthetized rats. In this study, we aimed to quantify the electrical SLN stimulation-induced systemic calcitonin release in conscious rats and to then clarify effects of chronic SLN stimulation on bone mineral density (BMD) in a rat ovariectomized disease model of osteoporosis. Cuff electrodes were implanted bilaterally on SLNs and after two weeks recovery were stimulated (0.5 ms, 90 microampere) repetitively at 40 Hz for 8 min. Immunoreactive c

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Takahashi, Takashi, Lauren MacCormick, Jutta Ellermann, Denis Clohisy, and Shelly Marette. "Giant Cell Tumor within the Proximal Tibia after ACL Reconstruction." Case Reports in Radiology 2016 (2016): 1–7. http://dx.doi.org/10.1155/2016/2820381.

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26-year-old female with prior anterior cruciate ligament reconstruction developed an enlarging lytic bone lesion around the tibial screw with sequential imaging over the course of one year demonstrating progression of this finding, which was confirmed histologically to be a giant cell tumor of bone. The lesion originated around the postoperative bed, making the diagnosis challenging during the early course of the presentation. The case demonstrates giant cell tumor which originated in the metaphysis and subsequently grew to involve the epiphysis; therefore, early course of the disease not invo

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Klaue, Kaj. "The circular arc internal fixation for tibio-talo-calcaneal arthrodesis." Foot & Ankle Orthopaedics 3, no. 3 (2018): 2473011418S0029. http://dx.doi.org/10.1177/2473011418s00295.

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Category: Hindfoot Introduction/Purpose: Stabilizing a tibio-talo-calcaneal arthrodesis in anatomical alignment allowing for weight bearing is a technical challenge. Normal anatomy demonstrates alignment of the heel, the posterior subtalar facet, the talus, the ankle joint and the distal tibia on a circular arc. This arc lies on a vertical plane which is slightly angulated inwards in relation to the sagittal plane. Today’s hindfoot nails do not respect this alignment. Complications include malalignment, primary instability, plantar neuropraxia. Purpose of the study is to optimize the technique

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Monzem, Samuel, Rafael Y. Ballester, Behzad Javaheri, et al. "Long-term bisphosphonate treatment coupled with ovariectomy in mice provokes deleterious effects on femoral neck fracture pattern and modifies tibial shape." Bone & Joint Open 1, no. 9 (2020): 512–19. http://dx.doi.org/10.1302/2633-1462.19.bjo-2020-0117.r1.

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Aims The processes linking long-term bisphosphonate treatment to atypical fracture remain elusive. To establish a means of exploring this link, we have examined how long-term bisphosphonate treatment with prior ovariectomy modifies femur fracture behaviour and tibia mass and shape in murine bones. Methods Three groups (seven per group) of 12-week-old mice were: 1) ovariectomized and 20 weeks thereafter treated weekly for 24 weeks with 100 μm/kg subcutaneous ibandronate (OVX+IBN); 2) ovariectomized (OVX); or 3) sham-operated (SHAM). Quantitative fracture analysis generated biomechanical propert

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Song, Jungbin, Sung Hyun Lee, Donghun Lee, and Hocheol Kim. "Astragalus Extract Mixture HT042 Improves Bone Growth, Mass, and Microarchitecture in Prepubertal Female Rats: A Microcomputed Tomographic Study." Evidence-Based Complementary and Alternative Medicine 2017 (2017): 1–7. http://dx.doi.org/10.1155/2017/5219418.

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Astragalus extract mixture HT042 is a standardized multiherbal mixture comprising Astragalus membranaceus, Eleutherococcus senticosus, and Phlomis umbrosa, which has proven to promote children’s height growth. The aim of this study was to investigate the effects of HT042 on longitudinal bone growth, bone mass, and bone microstructure in growing rats using a high-resolution microcomputed tomography system. Four-week-old female rats were fed an HT042-containing diet for 2 weeks. Tibial length was measured at baseline and weekly in vivo. At the end of the study, volumetric bone mineral density (v

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Flouzat-Lachaniete, Charles Henri, Xavier Roussignol, Alexandre Poignard, Martin Mukisi Mukasa, Olivier Manicom, and Philippe Hernigou. "Multifocal Joint Osteonecrosis in Sickle Cell Disease." Open Orthopaedics Journal 3, no. 1 (2009): 32–35. http://dx.doi.org/10.2174/1874325000903010032.

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The purpose of this study was to evaluate the frequency of multifocal osteonecrosis in patients with sickle cell disease. Between 1980 and 1989, 200 patients with sickle cell disease were treated in our institution for osteonecrosis. The patient population consisted of 102 males and 88 females with a mean age of twenty-six years at the time of presentation (range, eighteen to thirty-five years) and was followed until the year 2005. This cohort of patients was follow-up during average 15 years (until the year 2005). Multifocal osteonecrosis was defined as a disease of 3 or more anatomic sites.

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Deahl, Lauren, Ron Ben-Amotz, Ana Caceres, and Kimberly Agnello. "Proximal tibial metaphyseal fractures in immature dogs." Veterinary and Comparative Orthopaedics and Traumatology 30, no. 04 (2017): 237–42. http://dx.doi.org/10.3415/vcot-16-11-0154.

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SummaryObjective: To describe proximal tibial metaphyseal fractures in immature dogs.Materials and methods: Medical records of immature dogs with metaphyseal fractures of the proximal tibia were reviewed and data were collected on signalment and history of trauma. Craniocaudal and mediolateral radiographs were evaluated for the determination of the bones fractured, location of the fracture within the bone, fracture configuration, and the presence of fracture segment displacement and angulation.Results: Eighteen dogs with 22 proximal tibial metaphyseal fractures fulfilled the inclusion criteria

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Sarikaya, Baran, Fatih Suluova, Baki Volkan Cetin, and Zeynep Bekin Sarikaya. "Endoscopically Assisted Resection of a Rare Mass: Intra-Articular Osteochondroma of Shoulder Originated from Scapula." Case Reports in Orthopedics 2016 (2016): 1–4. http://dx.doi.org/10.1155/2016/7684807.

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Osteochondromas are the most common benign bone tumors which are mostly seen in the metaphysis of distal femur, proximal tibia, and proximal humerus. As arising from flat bones such as scapula is a rare case, intra-articular osteochondroma is also rare. When the literature is searched it appeared that the scapula and shoulder joint are an uncommon site for osteochondroma. We present a case in which a patient had an osteochondroma placed in shoulder joint and originated from scapula which is a rare situation determined in the literature.

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Harris, Mitchell C., Daniel C. DeRosa, and Priscilla A. West. "Subacute Osteomyelitis of the Pediatric Talus: A First Report of Brodie’s Abscess from Morganella morganii." Case Reports in Orthopedics 2019 (March 11, 2019): 1–4. http://dx.doi.org/10.1155/2019/7108047.

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Brodie’s abscess is a subacute form of osteomyelitis which generally occurs in the metaphysis of the femur and tibia in the pediatric population. Pathogens are most commonly Gram-positive bacteria, notably Staphylococcus and Streptococcus. In this article, we describe a young pediatric patient presenting with subacute ankle pain with a subsequent diagnosis of Brodie’s abscess of the talus secondary to Morganella morganii. We review the presentation, diagnosis, and treatment of this unique patient. To our knowledge, this is the first report of Morganella morganii as a cause of Brodie’s abscess.

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Bagi, Paul, and Raymond Walls. "Novel, vacuum-assisted method for harvesting autogenous cancellous bone graft and bone marrow from the proximal tibial metaphysis." Foot & Ankle Orthopaedics 3, no. 3 (2018): 2473011418S0014. http://dx.doi.org/10.1177/2473011418s00149.

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Category: Other Introduction/Purpose: Autogenous cancellous bone graft and bone marrow aspirate are commonly used in lower extremity fusion procedures. Autologous graft is considered the gold standard as it is osteogenic, osteoinductive, and osteoconductive, and is without the potential risks of graft-associated infection and immunologic reaction. Disadvantages include graft harvest time and donor site morbidity due to the surgical incision, approach and bone corticotomy. This study evaluated the safety and efficacy of a novel vacuum-assisted bone graft harvesting device which was able to obta

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Nakayama, Anna T., Laura J. Lutz, Adela Hruby, James P. Karl, James P. McClung, and Erin Gaffney-Stomberg. "A dietary pattern rich in calcium, potassium, and protein is associated with tibia bone mineral content and strength in young adults entering initial military training." American Journal of Clinical Nutrition 109, no. 1 (2019): 186–96. http://dx.doi.org/10.1093/ajcn/nqy199.

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ABSTRACT Background Stress fracture risk is elevated during initial military training (IMT), particularly in lower-extremity bones such as the tibia. Although the etiology of stress fractures is multifactorial, lower bone strength increases risk. Objective The objective of this study was to assess, through the use of peripheral quantitative computed tomography, whether adherence to a dietary pattern rich in calcium, potassium, and protein before IMT is positively associated with bone indexes in young adults entering IMT. Design A cross-sectional analysis was performed with the use of baseline

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Corsini, Marcelo Soeiro, Fátima N. Faraco, Alessandra A. Pereira Castro, Tatiana Onuma, Wilson R. Sendyk, and Jamil Awad Shibli. "Effect of Systemic Intermittent Administration of Human Parathyroid Hormone (RHPTH[1–34]) on the Resistance to Reverse Torque in Rabbit Tibiae." Journal of Oral Implantology 34, no. 6 (2008): 298–302. http://dx.doi.org/10.1563/1548-1336-34.6.298.

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Abstract The aim of this study was to evaluate the effect of intermittent administration of human parathyroid hormone [rhPTH (1–34)] on the removal torque of implants placed in rabbit tibiae. Twenty male New Zealand rabbits were submitted to implant surgery. Each animal received one machined screw-type implant (3.75 mm diameter × 8 mm length) in the proximal metaphysis of the right tibia. The rabbits were then divided into 2 groups: the test group (n = 10) received 6 μg/kg of rhPTH (1–34) subcutaneously in the dorsal region 3 days a week, and the control group (n = 10) received placebo. Remova

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Stöcker, D. S., S. Ohlerth, P. Grest, E. Mackenthun, R. Bettschart-Wolfensberger, and J. M. Kümmerle. "An unusual cyst-like lesion in the metaphysis of the tibia in a horse." Equine Veterinary Education 29, no. 5 (2015): 252–58. http://dx.doi.org/10.1111/eve.12430.

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PASSALI, C., A. PATSAKI, P. LELOVAS, et al. "Red wine polyphenols modulate bone loss in the ovariectomized rat model of postmenopausal osteoporosis." Journal of the Hellenic Veterinary Medical Society 70, no. 2 (2019): 1541. http://dx.doi.org/10.12681/jhvms.20860.

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The aim of this study was to examine the effect of Red Wine Polyphenols (RWPs) extract on bone mineral density (BMD) in the ovariectomized (OVX) rat model. Thirty-five 10-month-old Wistar rats were separated into controls (CTRL), OVX and OVX plus RWPs in their drinking water (dose, 50 mg/kg body weight per day), starting immediately after OVX for 6 months. Βody and uterine weight, BMD of the tibia at baseline, 3 and 6 months post-OVX, and 3-pointing bending of the femur, were examined. Statistical comparison of the total tibia BMD within groups during the study period showed a significant redu

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Blay, Alberto, Claudia C. Blay, Samy Tunchel, et al. "Effects of a Low-Intensity Laser on Dental Implant Osseointegration: Removal Torque and Resonance Frequency Analysis in Rabbits." Journal of Oral Implantology 42, no. 4 (2016): 316–20. http://dx.doi.org/10.1563/aaid-joi-d-15-00064.

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The objective of this study was to investigate how a low-intensity laser affects the stability and reverse torque resistance of dental implants installed in the tibia of rabbits. Thirty rabbits received 60 dental implants with the same design and surface treatment, one in each proximal metaphysis of the tibia. Three groups were prepared (n = 10 animals each): conventional osseointegration without treatment (control group), surgical sites irradiated with a laser beam emitted in the visible range of 680 nm (Lg1 group), surgical sites irradiated with a laser beam with a wavelength in the infrared

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[Author not found]. "The effect of zinc and 1α-OH-vitamin D_3 on the metaphysis of the tibia of growing rats". Journal of the Kyushu Dental Society 56, № 1 (2002): 1. http://dx.doi.org/10.2504/kds.56.1_2.

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Wadhawan, Piyush, Atul Agrawal, and Ruchit Khera. "Aneurysmal bone cyst of proximal fibula treated with en-bloc excision: a rare case report." International Journal of Research in Orthopaedics 5, no. 4 (2019): 736. http://dx.doi.org/10.18203/issn.2455-4510.intjresorthop20192695.

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Aneurysmal bone cysts (ABCs) are benign but locally destructive, blood filled reactive lesions of the bone. Although a wider age group may be affected, most commonly they are seen in patients younger than 20 years of age, with a slight female preponderance. Most common sites include metaphysis of femur followed by tibia and then humerus. Vertebral lesions involving the posterior elements are common.Aneurysmal bone cyst of proximal fibula is a rare and uncommon. Here, we report a case of 13 year old female with classic histologic, clinical, and radiographic findings that was treated by en bloc

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Shukla, Rajeev, and Nikhil Jain. "Aneurysmal Bone Cyst—An Unusual Presentation of Wrist Pain." Journal of Wrist Surgery 08, no. 01 (2018): 076–79. http://dx.doi.org/10.1055/s-0038-1660810.

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Introduction Aneurysmal bone cyst (ABC) is a cystic benign expansile lytic bone lesion, resembling multiple intraosseous blood-filled spaces. It is most commonly seen in the first two decades of life. Most frequent sites of involvement are metaphysis of proximal and distal femur, proximal tibia, and posterior elements of spine. It is seen more frequently in females. ABC of distal ulna is rarely reported in the literature. Case Presentation We are reporting a case of ABC of a rare location—distal ulna—in a young male, which was successfully treated with extended curettage, and the cavity was fi

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Xie, Liqin, Clinton Rubin, and Stefan Judex. "Enhancement of the adolescent murine musculoskeletal system using low-level mechanical vibrations." Journal of Applied Physiology 104, no. 4 (2008): 1056–62. http://dx.doi.org/10.1152/japplphysiol.00764.2007.

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Mechanical signals are recognized as anabolic to both bone and muscle, but the specific parameters that are critical to this stimulus remain unknown. Here we examined the potential of extremely low-magnitude, high-frequency mechanical stimuli to enhance the quality of the adolescent musculoskeletal system. Eight-week-old female BALB/cByJ mice were divided into three groups: baseline controls (BC, n = 8), age-matched controls (AC, n = 12), and whole body vibration (WBV, n = 12) at 45 Hz (0.3 g) for 15 min/day. Following 6 wk of WBV, bone mineralizing surfaces of trabeculae in the proximal metap

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Amizuka, N., H. Warshawsky, J. E. Henderson, D. Goltzman, and A. C. Karaplis. "Parathyroid hormone-related peptide-depleted mice show abnormal epiphyseal cartilage development and altered endochondral bone formation." Journal of Cell Biology 126, no. 6 (1994): 1611–23. http://dx.doi.org/10.1083/jcb.126.6.1611.

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To elucidate the role of PTHrP in skeletal development, we examined the proximal tibial epiphysis and metaphysis of wild-type (PTHrP-normal) 18-19-d-old fetal mice and of chondrodystrophic litter mates homozygous for a disrupted PTHrP allele generated via homologous recombination in embryonic stem cells (PTHrP-depleted). In the PTHrP-normal epiphysis, immunocytochemistry showed PTHrP to be localized in chondrocytes within the resting zone and at the junction between proliferative and hypertrophic zones. In PTHrP-depleted epiphyses, a diminished [3H]thymidine-labeling index was observed in the

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Haenle, Maximilian, Carmen Zietz, Tobias Lindner, et al. "A Model of Implant-Associated Infection in the Tibial Metaphysis of Rats." Scientific World Journal 2013 (2013): 1–8. http://dx.doi.org/10.1155/2013/481975.

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Objective. Implant-associated infections remain serious complications in orthopaedic and trauma surgery. A main scientific focus has thus been drawn to the development of anti-infective implant coatings. Animal models of implant-associated infections are considered helpful in thein vivotesting of new anti-infective implant coatings. The aim of the present study was to evaluate a novel animal model for generation of implant-associated infections in the tibial metaphysis of rats.Materials and Methods. A custom-made conical implant made of Ti6Al4V was inserted bilaterally at the medial proximal t

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Shannon, Claire E., Aaron J. Huser, and Dror Paley. "Cross-Union Surgery for Congenital Pseudarthrosis of the Tibia." Children 8, no. 7 (2021): 547. http://dx.doi.org/10.3390/children8070547.

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Congenital Pseudoarthrosis of the Tibia (CPT) is a rare condition with a reputation for recurrent fractures and failure to achieve union. A large variety of surgical procedures have been attempted for the treatment of fractured cases of CPT with an average rate of union without refracture of only 50%. Intentional cross-union between the tibia and fibula has been reported to improve these results to 100% union with no refractures. This is a retrospective study of 39 cases of CPT in 36 patients treated by the Paley cross-union protocol with internal fixation, bone grafting, zoledronic acid infus

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Qamar, Hammad, Muhammad Waqas, Aoyun Li, Mudassar Iqbal, Khalid Mehmood, and Jiakui Li. "Plastrum Testudinis Extract Mitigates Thiram Toxicity in Broilers via Regulating PI3K/AKT Signaling." Biomolecules 9, no. 12 (2019): 784. http://dx.doi.org/10.3390/biom9120784.

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Tibial dyschondroplasia (TD) negatively affects broilers all over the world, in which the accretion of the growth plate (GP) develops into tibial proximal metaphysis. Plastrum testudinis extract (PTE) is renowned as a powerful antioxidant, anti-inflammatory, and bone healing agent. The current study was conducted to evaluate the efficacy of PTE for the treatment of thiram-induced TD chickens. Broilers (day old; n = 300) were raised for 3 days with normal feed. On the 4th day, three groups (n = 100 each) were sorted, namely, the control (normal diet), TD, and PTE groups (normal diet+ thiram 50

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