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Relevant bibliographies by topics / Metastic Neoplasm / Dissertations / Theses

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Dissertations / Theses on the topic 'Metastic Neoplasm'

Author: Grafiati

Published: 3 June 2025

Last updated: 31 July 2025

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Consult the top 17 dissertations / theses for your research on the topic 'Metastic Neoplasm.'

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1

Casey, Susan Marie. "Metastatic recurrent breast cancer : the couples' experience with role changes /." Thesis, Connect to this title online; UW restricted, 2002. http://hdl.handle.net/1773/7253.

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2

Wedin, Rikard. "Metastatic bone disease /." Stockholm, 2000. http://diss.kib.ki.se/2000/91-628-3829-6/.

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3

Reed, Elizabeth. "The experience of living with metastatic breast cancer." Thesis, University of Southampton, 2012. https://eprints.soton.ac.uk/344746/.

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Over the last 10-15 years the medical management of metastatic breast cancer has improved survival, so women are living longer with progressive disease. Little is understood about women’s problems and needs and how they live their everyday lives. This study aimed to explore the experience of women with metastatic breast cancer by applying three phases: a cross-sectional survey exploring quality of life, experience of care and where they turned for support; exploration of the narratives of 30 women considering the social consequences of living with progressive breast cancer on identity; and fin

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4

Hughes, Ellyn. "Treating metastatic disease through manipulation of regulatory T cells." Thesis, Cardiff University, 2017. http://orca.cf.ac.uk/103925/.

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CD4+Foxp3+ regulatory T cells (Tregs) are the main regulators of peripheral tolerance and prevent the development of fatal autoimmune disease in humans and mice. Furthermore, Tregs have also been implicated in suppressing anti-tumour immune responses and are often enriched at sites of primary and metastatic tumours. While studies have shown the effect of Treg ablation on the control of primary tumours, few studies have examined their contribution to metastasis progression. In this thesis I hypothesised that the depletion of Tregs could promote control over metastasis. To address this, a highly

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5

Robinson, David. "Prediction of survival in prostate cancer : aspects on localised, locally advanced and metastatic disease." Doctoral thesis, Linköping : Department of Clinical and Experimental Medicine, Linköping University, 2008. http://www.bibl.liu.se/liupubl/disp/disp2008/med1073s.pdf.

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6

Bradbury, Robyn. "The interplay between MDM2 and PSMA in metastatic breast cancer cells." Thesis, Cardiff University, 2016. http://orca.cf.ac.uk/100068/.

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Both mouse double minute (MDM2) and prostate-specific membrane antigen (PSMA) are known to be associated with the progressive properties of cancer. Moreover, overexpression of both molecules has been implicated in an increase in the proliferation, migration and invasion of tumour cells. MDM2 is a negative regulator of tumour suppressor of p53 but also is known to play multiple p53-independent roles in many cancer types. PSMA was originally thought to be solely expressed in prostate tissues and overexpression prostatic cancers; however, recently its expression was reported in various other soli

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7

Soukupová, Jitka. "Inhibition of Bcl-3 as a novel therapeutic approach for metastatic breast cancer." Thesis, Cardiff University, 2013. http://orca.cf.ac.uk/52578/.

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B-Cell Lymphoma 3 (Bcl-3) is a proto-oncogene modulating the nuclear factor κB (NF-κB) signalling pathway, which had been first identified at the site of a t (14,19) translocation in B-cell chronic lymphocytic leukemia. Deregulated Bcl-3 expression has been reported in various tumours and in breast tumours Bcl-3 was found to be significantly elevated compared to the normal adjacent tissue. Activated NF-кB signalling is detected in 86% of ER-negative and HER2+ breast tumours. The currently used monoclonal antibody against HER2 (trastuzumab), produces remissions in 10-15 % of HER2+ breast cancer

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8

Mahteme, Haile. "Hepatic and Peritoneal Colorectal Metastases : Aspects of Prognosis and Treatment." Doctoral thesis, Uppsala : Acta Universitatis Upsaliensis : Univ.-bibl. [distributör], 2001. http://publications.uu.se/theses/91-554-4912-3/.

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9

Bordoni, Cinzia. "Discovery of Bcl-3 inhibitors for the potential treatment of metastatic breast cancer." Thesis, Cardiff University, 2016. http://orca.cf.ac.uk/97999/.

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In HER-2 positive metastatic breast cancer, the proto-oncogene Bcl-3 was found to be overexpressed. Bcl-3 acts as a transcriptional co-activator: it forms a ternary complex with DNA and homodimer (p50)2 and stimulates the transcription of a different panel of genes in the metastatic progression of the breast cancer. Its exact role in endogenous tumours is still unknown. In vivo knockdown studies shown, that Bcl-3 deficiency did not affect the primary tumour, but it reduced the occurrence of metastases by 80% without any effects on the normal mammary gland function. Patients with this type of t

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10

Jane, Sui-Whi. "Effects of a full-body massage on pain intensity, anxiety, and physiologic relaxation in Taiwanese patients with metastatic bone pain : a pilot study /." Thesis, Connect to this title online; UW restricted, 2005. http://hdl.handle.net/1773/7241.

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11

Lindman, Henrik. "Individually Tailored Toxicity-based Chemotherapy : Studies on Patients with Primary and Metastatic Breast Cancer." Doctoral thesis, Uppsala : Acta Universitatis Upsaliensis : Univ.-bibl. [distributör], 2003. http://urn.kb.se/resolve?urn=urn:nbn:se:uu:diva-3802.

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12

Duarte, Igor Lemos 1980. "Quimioterapia em dose densa no tratamento adjuvante do câncer de mama localizado = revisão sistemática da literatura com metanálise = Dose dense chemotherapy in the adjuvant treatment of non metastatic breast cancer: a systematic review with meta- analysis." [s.n.], 2015. http://repositorio.unicamp.br/jspui/handle/REPOSIP/313864.

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Orientadores: Andre Deeke Sasse, Carmen Silvia Passos Lima<br>Dissertação (mestrado) - Universidade Estadual de Campinas, Faculdade de Ciências Médicas<br>Made available in DSpace on 2018-08-27T13:13:47Z (GMT). No. of bitstreams: 1 Duarte_IgorLemos_M.pdf: 729678 bytes, checksum: 3da7b8934fdc3f3c7776ad13bc0dbd2b (MD5) Previous issue date: 2015<br>Resumo: Pacientes com câncer de mama localmente avançado são de alto risco para recidiva após ressecção cirúrgica com intuito curativo. Muitos estudos têm sido realizados na tentativa de se descobrir alguma intervenção adjuvante capaz de reduzir este

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13

Pobel, Cédric. "Characterization of de novo metastatic prostate cancer : an ancillary study of the PEACE-1 phase 3 clinical trial." Electronic Thesis or Diss., université Paris-Saclay, 2024. http://www.theses.fr/2024UPASL118.

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Le cancer de la prostate de novo métastatique sensible à la castration représente 5 à 10% des cancers de la prostate au diagnostic mais est responsable de 50% des décès lié aux cancers de la prostate tous stades confondus. Dans cette étude ancillaire de l'essai PEACE-1, notre hypothèse était que les variants agressifs ou neuroendocrine peuvent être détectés dès le diagnostic. Nous avons rapatrié de façon centralisée les prélèvements en paraffine des biopsies au diagnostic des patients inclus dans PEACE1 (NCT01957436) pour réaliser des analyses d'immunohistochimie (IHC), de séquençage de nouvel

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14

Gomez, Cintia Elisabeth 1983. "Modulação das vias de sinalização de sobrevivência, ciclo celular, resistência e potencial metastático pela etoxzolamida na linhagem celular de adenocarcinoma ductal de pâncreas humano (PANC-1) = Modulation of survival, cell cycle, resistance signaling pathways and metastatic potential by ethoxzolamide in human pancreatic ductal adenocarcinoma cell line (PANC-1)." [s.n.], 2013. http://repositorio.unicamp.br/jspui/handle/REPOSIP/314039.

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Orientador: Carmen Veríssima Ferreira Halder<br>Dissertação (mestrado) - Universidade Estadual de Campinas, Instituto de Biologia<br>Made available in DSpace on 2018-08-23T12:47:15Z (GMT). No. of bitstreams: 1 Gomez_CintiaElisabeth_M.pdf: 3156937 bytes, checksum: f31ea6c3519ce92ea0573b1cfd1549a1 (MD5) Previous issue date: 2013<br>Resumo: O câncer de pâncreas é considerado a quarta causa de morte por doenças malignas nos países ocidentais. Entre os tipos de câncer de pâncreas exócrino cerca de 80-90% dos casos correspondem ao adenocarcinoma ductal, um câncer altamente agressivo, invasivo, pot

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15

Beaton, Rebekah, Wendy Pagdin-Friesen, Christa Robertson, Cathy Vigar, and Heather Watson. "Effects of Exercise on Persons with Metastatic Cancer." 2008. http://hdl.handle.net/2429/1457.

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16

Tometich, Danielle B. "Symptom Severity and Importance in Metastatic Breast Cancer Patients: An Examination of Cognitive Complaints and Related Symptoms." Thesis, 2016. http://hdl.handle.net/1805/11017.

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Indiana University-Purdue University Indianapolis (IUPUI)<br>Cognitive changes associated with cancer and its treatment have been well documented. However, the majority of research on cognitive symptoms in cancer has been conducted with early-stage breast cancer patients or survivors in remission. Little is known about cognitive symptoms in patients with late-stage or metastatic cancers. To address this gap in the literature, this study examines cognitive and related symptoms among metastatic breast cancer patients enrolled in a parent study of perceptions of symptom importance and interfer

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17

"Investigation of the anti-tumor and anti-metastasis effects of selected Chinese medicines in metastatic breast cancer, and the combined use with zoledronate." 2013. http://library.cuhk.edu.hk/record=b5884437.

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Luo, Kewang.<br>Thesis (Ph.D.)--Chinese University of Hong Kong, 2013.<br>Includes bibliographical references (leaves 278-305).<br>Electronic reproduction. Hong Kong : Chinese University of Hong Kong, [2012] System requirements: Adobe Acrobat Reader. Available via World Wide Web.<br>Abstract also in Chinese.

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