Relevant bibliographies by topics / Metaxalone

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  1. Journal articles
  2. Dissertations / Theses
  3. Book chapters
  4. Conference papers

Academic literature on the topic 'Metaxalone'

Author: Grafiati
Published: 3 June 2025
Last updated: 31 July 2025

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Journal articles on the topic "Metaxalone"

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Yamaguchi, Masayoshi, та Robert M. Levy. "Metaxalone Suppresses Production of Inflammatory Cytokines Associated with Painful Conditions in Mouse Macrophages RAW264.7 Cells in Vitro: Synergistic Effect with β-caryophyllene". Current Molecular Medicine 20, № 8 (2020): 643–52. http://dx.doi.org/10.2174/1566524020666200217102508.

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Backgrounds and Objective: Inflammation is implicated in the pathogenesis of many diseases. Inflammatory cytokines with painful conditions are well known as biomarkers in human muscle pain, and they are produced by macrophages. Metaxalone is used as a skeletal muscle relaxant, but the mechanism by which metaxalone acts is unknown. This study was undertaken to investigate whether or not metaxalone exhibits an inhibitory effect on the activity of inflammatory macrophages in vitro. Methods: Mouse macrophage RAW264.7 cells were cultured in Dulbecco’s Modification of Eagle’s Medium containing 10% f
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Pallio, Giovanni, Angela D’Ascola, Luigi Cardia та ін. "MAO-A Inhibition by Metaxalone Reverts IL-1β-Induced Inflammatory Phenotype in Microglial Cells". International Journal of Molecular Sciences 22, № 16 (2021): 8425. http://dx.doi.org/10.3390/ijms22168425.

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Experimental and clinical studies have suggested that several neurological disorders are associated with the occurrence of central nervous system neuroinflammation. Metaxalone is an FDA-approved muscle relaxant that has been reported to inhibit monoamine oxidase A (MAO-A). The aim of this study was to investigate whether metaxalone might exert antioxidant and anti-inflammatory effects in HMC3 microglial cells. An inflammatory phenotype was induced in HMC3 microglial cells through stimulation with interleukin-1β (IL-1β). Control cells and IL-1β-stimulated cells were subsequently treated with me
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&NA;. "Gabapentin/metaxalone overdose." Reactions Weekly &NA;, no. 1074 (2005): 9. http://dx.doi.org/10.2165/00128415-200510740-00025.

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Lin, Hong-Liang, Tieh-Kang Wu, Yu-Ting Huang, and Shan-Yang Lin. "Studies on Cocrystal Formation of Metaxalone with Short-chain Dicarboxylic Acids." Acta Crystallographica Section A Foundations and Advances 70, a1 (2014): C658. http://dx.doi.org/10.1107/s2053273314093413.

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A possible cocrystal formation between metaxalone and short-chain dicarboxylic acids (HOOC-(CH2)n-COOH, n=0-3) was quickly investigated using a solvent-assisted grinding approach. Differential scanning calorimetry (DSC), Fourier transform infrared (FTIR) microspectroscopy, and powder X-ray diffraction (PXRD) were used to verify the cocrystal formation between metaxalone and each dicarboxylic acid. A solvent evaporation method was used to prepare the standard cocrystal. The cocrystal formation was also estimated by using a one-step simultaneous DSC-FTIR microspectroscopy. The present study indi
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Sahu, Prafulla Kumar, M. Mathrusri Annapurna, and Sahoo Dillip Kumar. "Development and Validation of Stability Indicating RP-HPLC Method for the Determination of Metaxalone in Bulk and its Pharmaceutical Formulations." E-Journal of Chemistry 8, s1 (2011): S439—S447. http://dx.doi.org/10.1155/2011/645710.

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A stability indicating reverse phase HPLC method was developed for the determination of metaxalone, a skeletal muscle relaxant, present in bulk and its pharmaceutical formulations using gliclazide as the internal standard (I.S). A hypersil ODS C18 column (250 × 4.6 mm, packed with 5 micron) in an isocratic mode with mobile phase Acetonitrile: phosphate buffer 3.6 (50:50%v/v) was used at a flow rate of 0.8 mL/ min and effluent was monitored at 225 nm. The assay exhibited a linear dynamic range of 0.6-100 µg/mL. Acceptable precision and accuracy were obtained for concentrations over the standard
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Nallakumar, P. *. and Siva Kumar R. "BIOANALYTICAL METHOD DEVELOPMENT, VALIDATION AND QUANTIFICATION OF METAXALONE BY LIQUID CHROMATOGRAPHY TANDEM MASS SPECTROMETRY IN RAT PLASMA." Indo American Journal of Pharmaceutical Sciences 04, no. 07 (2017): 2128–38. https://doi.org/10.5281/zenodo.836457.

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A simple, highly sensitive, precise and accurate high-performance liquid chromatographic (LCMSMS) method with mass detection was developed and validated for the rapid quantiication of metaxalone (CAS Registry No, 1665-48- 1) in rat plasma samples. The chromatographic separation was achieved with a reverse phase column Agilent XDB C18 (4.6×100 mm, 5µ) and the mobile phase consisted of methanol and 5 mm ammonium acetate buffer (80:20 v/v) as eluent, at a low rate of 0.6 mL/min. Phenytoin (CAS Registry no, 57-41-0) was used as an internal standard. The efluence was ionized by positive electrospra
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Ashish, Jain* Srushti Kadave Mukesh Patil Rupali Bothara Swati Borase. "Development and Validation of Metaxalone and Diclofenac Potassium in Bulk and Its Formulation using RP-HPLC Techniques." International Journal of Pharmaceutical Sciences 2, no. 12 (2024): 2120–31. https://doi.org/10.5281/zenodo.14481671.

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This research article aims to develop and validate the Reverse-Phase High-Performance Liquid Chromatography (RP-HPLC) technique for the simultaneous determinations of Diclofenac potassium and Metaxalone in tablets and bulk. On an Eclipse plus C<sub>18</sub> (250 mm &times; 4.6 mm ID, 5&mu;m) column, chromatographic separation was accomplished with a mobile phase consisting of potassium dihydrogen phosphate buffer (pH 4.2): acetonitrile (30:70 v/v) at a flow rate of 1 ml/min. The detection wavelength was selected to be 280 nm. Diclofenac potassium and Metaxalone were shown to have retention per
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Moore, Karla A., Barry Levine, and David Fowler. "A fatality involving metaxalone." Forensic Science International 149, no. 2-3 (2005): 249–51. http://dx.doi.org/10.1016/j.forsciint.2004.07.017.

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&NA;. "Levetiracetam/metaxalone/neuropsychotherapeutics/opioids." Reactions Weekly &NA;, no. 1430 (2012): 21. http://dx.doi.org/10.2165/00128415-201214300-00073.

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Gruszecki, Amy C., Susan Kloda, Gary T. Simmons, Thomas M. Daly, Robert W. Hardy, and C. Andrew Robinson. "Polydrug Fatality Involving Metaxalone." Journal of Forensic Sciences 48, no. 2 (2003): 2002286. http://dx.doi.org/10.1520/jfs2002286.

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Dissertations / Theses on the topic "Metaxalone"

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Song, Ta-Shu, and 宋達樞. "Comparative Bioavailability of Three Metaxalone Tablets in Chinese Healthy Volunteers." Thesis, 2006. http://ndltd.ncl.edu.tw/handle/73586747252473099301.

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碩士<br>中國醫藥大學<br>藥學系碩士班<br>94<br>Abstract Metaxalone (5-[(3,5-dimethylphenoxy)methyl]-2-oxazolidinone) is a centrally acting skeletal muscle relaxant. Clinically, it is used for the relief of discomforts associated with acute, painful muscloskeletal conditions. Because it is good to relax the skeletal muscle spasm and has less side effect, higher safety, so it is used extensive in USA. It is necessary to research the drug’s pharmacokinetic in our country’s man to provide the medical reference data. In this study, the plasma levels from three metaxalone 800 mg tablet formulations in twelve heal
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Book chapters on the topic "Metaxalone"

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"METAXALONE." In Litt's Drug Eruption and Reaction Manual. CRC Press, 2015. http://dx.doi.org/10.1201/b17996-85.

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"Metaxalone." In Hale’s Medications & Mothers’ Milk™ 2019. Springer Publishing Company, 2018. http://dx.doi.org/10.1891/9780826150356.0653.

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Conference papers on the topic "Metaxalone"

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Pawar, Shivani S., Bhushan R. Rane, and Ashish S. Jain. "Development and Evaluation of Nanoemulsion Loaded Metaxalone for the Treatment of Pain and Injury." In ASEC 2023. MDPI, 2023. http://dx.doi.org/10.3390/asec2023-15285.

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Journal articles
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