Academic literature on the topic 'Metformin Hydrochloride'

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Journal articles on the topic "Metformin Hydrochloride"

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K, Vijay, and Naruka PS. "Latest Advancements on Gastro Floating Bi-Layer Tablets of Metformin and Pioglitazone for the Treatment of Diabetes Mellitus." INTERNATIONAL JOURNAL OF DRUG DELIVERY TECHNOLOGY 14, no. 04 (2024): 1683–93. https://doi.org/10.25258/ijddt.14.4.76.

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The synergistic mode of action of pioglitazone hydrochloride (PG) and metformin hydrochloride (MH) has great potential for the treatment of type 2 diabetes mellitus. Because of their complementary modes of action, metformin hydrochloride (MH) and pioglitazone hydrochloride (PG) have great potential for the therapy of type 2 diabetes mellitus. Short half-life and the low absorption of metformin hydrochloride in lower gastrointestinal tract might restrict the action towards its expected therapeutic usefulness. This work aimed to create gastro-floating bilayer matrix tablets that would each conta
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K, Vijay, and Naruka PS. "Latest Advancements on Gastro Floating Bi-Layer Tablets of Metformin and Pioglitazone for the Treatment of Diabetes Mellitus." INTERNATIONAL JOURNAL OF DRUG DELIVERY TECHNOLOGY 14, no. 04 (2024): 1683–93. https://doi.org/10.25258/ijddt.14.4.77.

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The synergistic mode of action of pioglitazone hydrochloride (PG) and metformin hydrochloride (MH) has great potential for the treatment of type 2 diabetes mellitus. Because of their complementary modes of action, metformin hydrochloride (MH) and pioglitazone hydrochloride (PG) have great potential for the therapy of type 2 diabetes mellitus. Short half-life and the low absorption of metformin hydrochloride in lower gastrointestinal tract might restrict the action towards its expected therapeutic usefulness. This work aimed to create gastro-floating bilayer matrix tablets that would each conta
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&NA;. "Glucophage (Metformin Hydrochloride)." Gastroenterology Nursing 19, no. 3 (1996): 113–16. http://dx.doi.org/10.1097/00001610-199605000-00008.

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Solanki, MS, and PK Goyal. "Simultaneous Estimation of Teneligliptin and Metformin Hydrochloride in Tablet Formulation by UV Spectrophotometric Method." Chemistry Research Journal 6, no. 6 (2021): 160–65. https://doi.org/10.5281/zenodo.12092999.

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<strong>Abstract </strong>Simple, sensitive and accurate UV-spectroscopic methods were developed and validated for simultaneous estimation of Teneligliptin and Metformin Hydrochloride in tablet formulation using simultaneous equation method. Wavelengths which could be utilized for simultaneous analysis of TGN and MET were 245 nm (&lambda;<sub>max</sub> of TGN) and 233 nm (&lambda;<sub>max</sub> of MET) respectively from the overlain spectra. Linearity was found to be satisfactory over the concentration range of 1-30 &mu;g/ml for both the drugs. The mean percentage label claim of Teneligliptin
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Rajagopal, Ponnu lakshmi. "Molecular docking analysis of metformin analogues with GSK-3β". Bioinformation 18, № 3 (2022): 269–72. http://dx.doi.org/10.6026/97320630018269.

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We report the molecular docking analysis of four analogues of metformin [1-Carbamimidoyl-1,2-dimethylguanidine hydrochloride, Metformin hydrochloride, N1,N1-Dimethyl-N5-methylbiguanide hydrochloride, and N1,N1,N5,N5-Tetrakis(methyl-biguanide hydrochloride] with GSK3.
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Shilpa, Lakinapally* Ramakrishna Raparla. "DEVELOPMENT AND VALIDATION OF ANALYTICAL METHOD FOR THE SIMULTANEOUS ESTIMATION OF METFORMIN AND METOPROLOL FROM COMBINATION DOSAGE FORMS." Journal of Pharma Research 11, no. 06 (2022): 66–71. https://doi.org/10.5281/zenodo.7472721.

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<strong><em>ABSTRACT</em></strong> <strong>A</strong>n effortless, hasty, unambiguous, robust, exact as well as precise isocratic high performance liquid chromatographic technique has been urbanized in addition to validated for the assessment of simultaneous estimation of Metformin Hydrochloride and Metoprolol Tartrate from the plasma samples. The chromatographic severance was accomplished on Phenomenex kinetex C18 (250mm&times;4.6mm i.d, 5&micro;m) column by means of a mobile phase mixture containing methanol: buffer of pH 6.8: ACN in the proportion of 47:23:30 respectively at a flow rate of
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Borole, T., M. Dewani, S. Gandhi, and M. Damle. "SIMULTANEOUS ESTIMATION OF METFORMIN HYDROCHLORIDE AND REPAGLINIDE BY HPLC METHOD." INDIAN DRUGS 49, no. 01 (2012): 54–60. http://dx.doi.org/10.53879/id.49.01.p0054.

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A reverse phase high performance liquid chromatographic method is developed for the simultaneous determination of metformin hydrochloride and repaglinide. Chromatography was carried out at ambient temperature and separation of these drugs was achieved on neosphere C18 column (150 x 4.6 mm i.d, 3.5 mcgm) as stationary phase with a mobile phase comprising of methanol: 0.05 M acetate buffer (pH 3.5) in ratio of (80:20 V/V) at flow rate 0.8 mL/min. The detection wavelength for metformin hydrochloride and repaglinide was 242 nm. The retention times for metformin hydrochloride and repaglinide were 1
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Ali, Azzam R., Ibrahim I. Duraidi, Munib M. Saket, and Eyad S. M. Abu-Nameh. "Column High-Performance Liquid Chromatographic Method for the Simultaneous Determination of Rosiglitazone and Metformin in a Pharmaceutical Preparation." Journal of AOAC INTERNATIONAL 92, no. 1 (2009): 119–24. http://dx.doi.org/10.1093/jaoac/92.1.119.

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Abstract An efficient, sensitive, and simple method was developed for the simultaneous determination of rosiglitazone and metformin hydrochloride in a combination tablet dosage form by column high-performance liquid chromatography. The mobile phase used was ammonium dihydrogen phosphate adjusted to pH 5.25 with sodium hydroxide. The limits of detection and quantitation were in the range of 0.51.6 g/mL, respectively, for metformin hydrochloride, and 0.002010.0067 g/mL, respectively, for rosiglitazone. The linearity was studied in the concentration range of 0.120.31 g/mL for rosiglitazone and 30
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Podolsky, I. M., I. M. Vladymyrova, A. V. Volkova, D. V. Lytkin, and О. О. Ryshchenko. "Analysis of the range of metformin hydrochloride medicines for the treatment of type II diabetes mellitus." Social Pharmacy in Health Care 8, no. 2 (2022): 67–73. http://dx.doi.org/10.24959/sphhcj.22.251.

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Aim. To analyze the range of metformin hydrochloride medicines registered at the pharmaceutical market of Ukraine for the treatment of type II diabetes mellitus.Materials and methods. When conducting the analysis the data of the State Register of Medicines of Ukraine, namely, reference resources, in particular the Compendium drug reference book, unified clinical protocols for the treatment of type II diabetes in adults, were used as research materials. In the course of the study, documentary, analytical, mathematical-statistical and logical data generalization methods were used. Graphical and
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Harshada, Vaid* Rachana Kamble Vaishnavi Rahane Suhani Bhagat. "A Review on Anti- Diabetic of Transdermal Patches." International Journal of Pharmaceutical Sciences 3, no. 5 (2025): 5125–29. https://doi.org/10.5281/zenodo.15560751.

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The primary goal of this study was to create, develop, and test a transdermal drug delivery system containing Metformin hydrochloride to address the key issues associated with the oral route. Metformin hydrochloride transdermal patches were manufactured utilizing the solvent evaporation process. Different formulation trials were conducted by varying the polymer ratios. The thickness, weight fluctuation, and percentage of transdermal patch compositions were all measured. Moisture content, research, and metformin transdermal patches provide a simple and effective means of regulating blood glucos
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Dissertations / Theses on the topic "Metformin Hydrochloride"

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Freire, Petrovick Gustavo [Verfasser], Jörg [Akademischer Betreuer] Breitkreutz, and Peter [Akademischer Betreuer] Kleinebudde. "Orodispersible Tablets Containing Taste-Masked Lipid Pellets with Metformin Hydrochloride for Use by Elderly Patients / Gustavo Freire Petrovick. Gutachter: Jörg Breitkreutz ; Peter Kleinebudde." Düsseldorf : Universitäts- und Landesbibliothek der Heinrich-Heine-Universität Düsseldorf, 2015. http://d-nb.info/1073642097/34.

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Book chapters on the topic "Metformin Hydrochloride"

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Bretnall, Alison E., and Graham S. Clarke. "Metformin Hydrochloride." In Analytical Profiles of Drug Substances and Excipients. Elsevier, 1998. http://dx.doi.org/10.1016/s0099-5428(08)60757-1.

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Panda, Simanchal. "Advanced Drug Delivery Systems: Formulating and Evaluating Metformin SR Tablets with Fenugreek Seed Mucilage." In Deep Science Publishing. Deep Science Publishing, 2025. https://doi.org/10.70593/978-81-984306-6-3.

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This book explores into the innovative formulation of metformin hydrochloride using fenugreek seed mucilage as a natural polymer. It bridges traditional botanical knowledge with modern pharmaceutical science to enhance the effectiveness and patient compliance of metformin, a key treatment for diabetes. The chapters meticulously detail the scientific process from raw material procurement to rigorous post-formulation evaluations, underlining our commitment to improving diabetic care through advanced drug delivery systems. By combining traditional fenugreek uses with contemporary pharmaceutical t
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Varade, Rajesh, and Harsha Mishra. "Estimation of Metformin Hydrochloride, Gliclazide and Pioglitazone Hydrochloride: A UDDD-HPTLC Densitometry Method Validation Study." In Novel Aspects on Pharmaceutical Research Vol. 3. B P International (a part of SCIENCEDOMAIN International), 2023. http://dx.doi.org/10.9734/bpi/napr/v3/5781e.

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Aleti, Rajeswari, Sailaja Gunnam, and Monika Nijhawan. "A Combination Therapy for Diabetes Miletus Using Metformin Hydrochloride and Gliclazide Bilayer Tablets." In Pharmaceutical Research - Recent Advances and Trends Vol. 4. B P International, 2024. http://dx.doi.org/10.9734/bpi/prrat/v4/1115.

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Silva, Ariadne Gisele da, and Gyzelle Pereira. "METFORMIN HYDROCHLORIDE AS A TREATMENT ALTERNATIVE IN PATIENTS WITH POLYCYSTIC OVARY SYNDROME (PCOS)." In Health promotion studies. Brazilian Journals Editora, 2025. https://doi.org/10.55905/edicon.978-65-6016-093-4_12.

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Conference papers on the topic "Metformin Hydrochloride"

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Zhang, Jinxia, Zijian Liu, Zhehan Zhong, et al. "Interface Modification by Metformin Hydrochloride for MA-Free Perovskite Solar Cells." In 2024 9th International Conference on Clean Energy and Power Generation Technology (CEPGT). IEEE, 2024. https://doi.org/10.1109/cepgt64143.2024.11064765.

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Khalaf, M., A. Elsaid, S. F. Hammad, and W. K. Zahra. "Memory-based model of drug release from Metformin Hydrochloride/Vildagliptin tablets." In INTERNATIONAL CONFERENCE OF NUMERICAL ANALYSIS AND APPLIED MATHEMATICS: ICNAAM2022. AIP Publishing, 2024. http://dx.doi.org/10.1063/5.0210603.

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Wibowo, Ari, Vitarani D. A. Ningrum, and Nailatul Izzah. "Stability test of metformin hydrochloride in human plasma using HPLC-UV for the protocol of therapeutic drug monitoring of metformin." In 2ND INTERNATIONAL CONFERENCE ON CHEMISTRY, CHEMICAL PROCESS AND ENGINEERING (IC3PE). Author(s), 2018. http://dx.doi.org/10.1063/1.5064982.

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Mariadi, Bayu Eko Prasetyo, and Yade Metri Permata. "Optimization of Polymer and Cross-linker Combination on the Formation of Pectin Film Containing Metformin Hydrochloride." In International Conference of Science, Technology, Engineering, Environmental and Ramification Researches. SCITEPRESS - Science and Technology Publications, 2018. http://dx.doi.org/10.5220/0010093608450851.

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Tarigan, Rida Evalina, Adina Saraswaty Silitonga, Melia Sari, and Syarifah Nadia. "Development and validation of mean centering ratio spectra spectrophotometry method for binary mixture of glimepiride and metformin hydrochloride in tablet disage form." In THE II INTERNATIONAL SCIENTIFIC CONFERENCE “INDUSTRIAL AND CIVIL CONSTRUCTION 2022”. AIP Publishing, 2023. http://dx.doi.org/10.1063/5.0136130.

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Qasim, Shahad M., Nadher D. Radhy, Aseel M. Aljeboree, Layth S. Jasim, and Ibrahim J. Sahib. "Kinetics study of metformin hydrochloride and hydroxychloroquine sulfate drugs from aqueous solutions onto (carrageenan/carboxy methyl cellulose-g-poly acrylic acid) hydrogel." In 4TH INTERNATIONAL SCIENTIFIC CONFERENCE OF ALKAFEEL UNIVERSITY (ISCKU 2022). AIP Publishing, 2023. http://dx.doi.org/10.1063/5.0182288.

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