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Dissertations / Theses on the topic 'Methamphetamine'

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1

Weber, Lloyd E. "The illicit methamphetamine landscape of Franklin County, Missouri application and analysis of a GIS-based risk assessment model /." Diss., Columbia, Mo. : University of Missouri-Columbia, 2006. http://hdl.handle.net/10355/4513.

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Thesis (M.A.)--University of Missouri-Columbia, 2006.<br>The entire dissertation/thesis text is included in the research.pdf file; the official abstract appears in the short.pdf file (which also appears in the research.pdf); a non-technical general description, or public abstract, appears in the public.pdf file. Title from title screen of research.pdf file (viewed on April 21, 2009.) Includes bibliographical references.
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2

Chen, Chih-Ken. "Predisposing factors to methamphetamine psychosis." Thesis, King's College London (University of London), 2001. http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.274936.

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3

Cotton, Sarah May. "Executive functioning in methamphetamine psychosis." Doctoral thesis, University of Cape Town, 2014. http://hdl.handle.net/11427/8714.

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Includes bibliographical references.<br>An association between methamphetamine dependence and neurocognitive impairment has long been established. However, there are a number of research gaps. First, while evidence suggests that the primary cognitive domains affected in methamphetamine dependence are executive functions; previous research fails to employ a comprehensive battery of executive functioning tests. Second, there is little research investigating the specific neuropsychological impairments associated with methamphetamine psychosis in particular. Third, ADHD is highly co-morbid with su
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4

Halpin, Laura E. "The Contribution of Ammonia to Methamphetamine Neurotoxicity." University of Toledo Health Science Campus / OhioLINK, 2013. http://rave.ohiolink.edu/etdc/view?acc_num=mco1370868834.

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5

Herring, Nicole Reneé. "Effects of Methamphetamine in the Adult Rat." University of Cincinnati / OhioLINK, 2007. http://rave.ohiolink.edu/etdc/view?acc_num=ucin1187007484.

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Herring, Nicole Renee. "Effects of Methamphetamine in the Adult Rat." Cincinnati, Ohio : University of Cincinnati, 2007. http://rave.ohiolink.edu/etdc//view?acc_num=ucin1187007484.

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Thesis (Ph.D.)--University of Cincinnati, 2007.<br>Advisor: Dr. Michael T. Williams PhD (Committee Chair), Charles V. Vorhees PhD, Ton J. Degrauw MD, PhD, Kim B. Seroogy PhD, Gary A. Gudelsky PhD. Title from electronic thesis title page (viewed Mar. 28, 2009). Keywords: Methamphetamine; Path Integration; Spatial Navigation; Corticosterone; Adrenalectomy. Includes abstract. Includes bibliographical references.
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7

Lapworth, Kely Narelle. "An Investigation of Aggression in Methamphetamine Users." Thesis, Griffith University, 2011. http://hdl.handle.net/10072/366564.

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Methamphetamine (MA) use is associated with increased aggression, though the specific mechanisms through which this association operates remain unclear. Research has demonstrated an association between MA, heightened impulsivity and reduced behavioural control. Similarly, there is strong evidence of a link between MA use and psychotic symptoms. Despite research efforts examining these independent associations, there is a paucity of studies examining how these factors interact to influence the relationship between MA use and aggression. Study 1 was conducted to examine the independent and combi
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8

Kennedy, Kelsey Marie. "The Relapse Cycles of Female Methamphetamine Users." Thesis, The University of Arizona, 2015. http://hdl.handle.net/10150/579257.

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Methamphetamine use, especially in rural populations, has vast implications on the community and the individuals that comprise it. It has been found that men and women display diverse methamphetamine habits as well as varied effectiveness in treatment. Due to the higher intake and drug-seeking behavior of female methamphetamine users, this qualitative study focused on the relapse and quitting cycles of women in rural Wyoming. Through analysis of forty five semi-structured interviews, it was found that the five major themes of relationships, health, treatment, Department of Corrections, and lif
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9

Weeden, Christy Samantha Star. "Neuroprotective Potential of Methamphetamine: Behavioral and Histological Analysis." Thesis, Montana State University, 2007. http://etd.lib.montana.edu/etd/2007/weeden/WeedenC0507.pdf.

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Stroke is a leading cause of death and ischemic stroke is the most common form. The deficits that follow ischemic stroke include memory and learning impairment. There are presently no treatments that can combat the effects of ischemia after the attack has occurred. Immediately following insult, locomotor activity increases in rodent models. The goal of the current research is to determine if methamphetamine administration following ischemic attack will have neuroprotective effects and prevent changes in locomotor behavior that are observed following insult. Ischemic insult was induced in gerbi
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10

Lowther, Courtney. "The Acute, Chronic, and Teratological Effects of Methamphetamine on Aggressive Behaviour in Adolescent Hooded Rats." Thesis, University of Canterbury. Psychology, 2012. http://hdl.handle.net/10092/7044.

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Methamphetamine is a widely abused psychostimulant often associated with aggressive, violent, and criminal behaviour. Research into the effects of adolescent methamphetamine use on aggressive behaviour is limited. This study aimed to establish whether methamphetamine would induce aggressive behaviour following an acute dosing regimen and a chronic dosing regimen. It also aimed to establish a teratological or delayed effect on adult behaviour. To investigate this 20 male and 20 female adolescent rats were equally divided into treatment and control conditions. The treatment condition received a
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11

Rocha, Angelica. "Methamphetamine self-administration in rats developmentally exposed to lead." [College Station, Tex. : Texas A&M University, 2007. http://hdl.handle.net/1969.1/ETD-TAMU-1370.

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12

Hagen, Gawie. "The impact of methamphetamine (tik) use on the workplace." Thesis, Stellenbosch : Stellenbosch University, 2008. http://hdl.handle.net/10019.1/14622.

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Thesis (MBA)--Stellenbosch University, 2008.<br>ENGLISH ABSTRACT: There has been a dramatic increase in the use of the drug methamphetamine, also known locally as tik, in the Western Cape, specifically in Cape Town. This trend impacts the availability and the quality of labour as well as the productivity of current employees. The presence of tik abuse in the workplace represents both legal and ethical challenges to employers. The Labour Relations Act of 1995 states that employers must ensure a safe working environment for their employees. The actions of tik users tend to increase the ris
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13

Thrash, Bessy Suppiramaniam Vishnu Dhanasekaran Muralikrishnan. "Neuroprotection against methamphetamine induced neurotoxicity applications for Parkinson's disease /." Auburn, Ala, 2009. http://hdl.handle.net/10415/1718.

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14

King, Kristine M. "An evaluation of a methamphetamine intervention on drug markets." abstract and full text PDF (UNR users only), 2009. http://0-gateway.proquest.com.innopac.library.unr.edu/openurl?url_ver=Z39.88-2004&rft_val_fmt=info:ofi/fmt:kev:mtx:dissertation&res_dat=xri:pqdiss&rft_dat=xri:pqdiss:1464445.

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15

Zabida, Omer Saleh. "The effect of methamphetamine on the blood-testis barrier." University of the Western Cape, 2018. http://hdl.handle.net/11394/6775.

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>Magister Scientiae - MSc<br>Introduction The blood-testis barrier (BTB) is formed by tight junctions between adjacent Sertoli cells. The barrier formed by these tight junction helps to create a specialized environment for spermatogenesis and provide an immunological barrier to protect developing germ cells. Methamphetamine (Meth) is known as neurotoxin however, its effects on the male reproductive system, especially on Sertoli cells and, the BTB are not well established. Therefore, this study aimed to determine the effects of Meth on the TM4 mouse testis Sertoli cell line and on the integrit
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16

Brown, Stacy D. "Methods for Confirmatory Analysis of Methamphetamine in Biological Samples." Digital Commons @ East Tennessee State University, 2012. https://dc.etsu.edu/etsu-works/5333.

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Methamphetamine is the most common amphetamine used and, along with 3,4-methylenedioxymethamphetamine (MDMA, Ecstasy), is considered part of a worldwide drug epidemic. Monitoring metham-phetamine levels in the body is important for purposes of drug screening for employment, criminal investigations, and therapeutic drug monitoring. While methamphetamine is suitable for detection using immunoassay techniques, these methods tend to have significant cross reactivity with other compounds. Over the last decade, more than eighty different quantitative, confirmatory analytical methods for measuring me
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Swanke, Jayme Rae. "EMPLOYED VS UNEMPLOYED METHAMPHETAMINE USERS: SPECIFIC IMPLICATIONS FOR CASE MANAGERS." OpenSIUC, 2009. https://opensiuc.lib.siu.edu/dissertations/109.

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Substance abuse and dependence has been a problem in the United States for over 100 years (Whitebread, 1995). In the past two decades the abuse and dependence of methamphetamine has increased and the rates have remained steady (Substance Abuse and Mental Health Services Administration, 2004). Advances have been made in the development of treatments for substance abuse and dependence. Research has continued to show that treatment modalities enhanced by case management services are more effective in the treatment of substance abuse and dependence. There has also been progress made in the researc
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18

Roussell, Aaron. "Wyoming ice social disorganization and methamphetamine use in a rural state /." Laramie, Wyo. : University of Wyoming, 2007. http://proquest.umi.com/pqdweb?did=1317343901&sid=1&Fmt=2&clientId=18949&RQT=309&VName=PQD.

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Swanke, Jayme R. "Employed vs unemployed methamphetamine users : specific implications for case managers /." Available to subscribers only, 2009. http://proquest.umi.com/pqdweb?did=1968461061&sid=1&Fmt=2&clientId=1509&RQT=309&VName=PQD.

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20

Clavenstam, Isabell. "The Effect of Methamphetamine Abuse on Brain Structure and Function." Thesis, University of Skövde, School of Humanities and Informatics, 2009. http://urn.kb.se/resolve?urn=urn:nbn:se:his:diva-3106.

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<p>The great amount of METH abuse all over the world causes enormous social and criminal justice problems. In the human brain the abuse of METH causes implications on both structures and functions given rise to acute as well as long term symptoms. In this essay the effects of METH abuse is described in the manner of the drug mechanism such as the impact on neurotransmitters, structural deficits with decreased and increased volumes and the implication on attention, memory, decision  making and emotions. Results from studies showing brain structural and cognitive impairments in METH abusers and
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21

Kalula, Asha Saidi. "Modelling the dynamics of methamphetamine abuse in the Western Cape." Thesis, Stellenbosch : University of Stellenbosch, 2011. http://hdl.handle.net/10019.1/6817.

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Thesis (MSc (Mathematical Sciences))--University of Stellenbosch, 2011.<br>Includes bibliography<br>ENGLISH ABSTRACT: The production and abuse of methamphetamine has increased dramatically in South Africa, especially in the Western Cape province. A typical methamphetamine use cycle consists of concealed use after initiation, addiction, treatment and recovery. The model by Nyabadza and Musekwa in [32], is extended to include a core group, fast and slow progression to addiction. The model is analysed analytically and numerically using mass action incidence function and non-linear incidence
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22

Linnemann, Travis. "Beyond the ghetto: methamphetamine and the punishment of rural America." Diss., Kansas State University, 2011. http://hdl.handle.net/2097/12021.

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Doctor of Philosophy<br>Department of Sociology, Anthropology, and Social Work<br>L. Susan Williams<br>Since the early 1970s, the United States has grown increasingly reliant on the criminal justice system to manage a wide array of social problems. Aggressive drug control policies and an over-reliance on imprisonment helped produce the world’s largest prison and correctional population, often described as mass imprisonment. Within this context, the study provides an explanatory account of the political, cultural, and social conditions that encourage states like Kansas to pursue methamphetami
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23

Darsamo, Arnalda Vanessa. "The societal costs of methamphetamine use in Western Cape Province." Master's thesis, University of Cape Town, 2016. http://hdl.handle.net/11427/20849.

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Methamphetamine (meth) use results in various costs accruing to the meth user, society, and government. Internal and external costs of the pandemic are widespread, affecting the healthcare and social welfare systems, policing, private security, and the judicial and corrective services system. This study quantifies these costs for the Western Cape; identifying the magnitude of the cost of illness and additional social costs by category and determines which interventions are likely to reduce these overall costs. This study used a combination of a top-down and a bottom-up approach for the costing
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24

Lederer, Katharina Johanna. "Relationship between white matter changes and aggression in methamphetamine dependence." Master's thesis, University of Cape Town, 2015. http://hdl.handle.net/11427/13802.

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Background: Methamphetamine (MA) abuse is a growing problem in the world and especially in South Africa’s Western Cape. Amphetamine-type stimulants have become the second most widely abused illicit drugs worldwide. Admission data from substance abuse treatment centres in the Western Cape show the fastest increase for any drug ever noted in the country in MA related admissions. MA has neurotoxic effects on the brain leading, amongst other effects, to white matter (WM) changes. Moreover, increased levels of aggression are commonly found in individuals with MA abuse. Although behavioural defici
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25

Moodley, Aneshree. "Methamphetamine use and HIV risk among severely mentally ill inpatients." Master's thesis, University of Cape Town, 2013. http://hdl.handle.net/11427/10989.

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Includes bibliographical references.<br>Sub-Saharan Africa accounts for 69% of the global HIV burden. Due to a variety of social, economic and behavioural factors, mentally ill patients are more likely to engage in high risk sexual behaviours. In turn, co-morbid substance use which is present in up to 75% of mentally ill patients is a leading risk factor for sexual risk behaviours. Worldwide methamphetamines are the most commonly used illicit stimulant. Both injectable and noninjectable methamphetamines have evidenced associations with high risk sexual behaviours. Smoking and inhalation of cry
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26

Alshehri, Fahad. "Role of Glutamate Transporters in Alcohol and Methamphetamine Co-Abuse." University of Toledo / OhioLINK, 2015. http://rave.ohiolink.edu/etdc/view?acc_num=toledo1433195506.

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27

Gutierrez, Arnold. "The role of dopamine receptors in methamphetamine-induced cognitive deficits." University of Cincinnati / OhioLINK, 2018. http://rave.ohiolink.edu/etdc/view?acc_num=ucin1521189209471948.

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28

Baicy, Kate. "Dissociation between neural processing and negative emotion in methamphetamine dependence." Diss., Restricted to subscribing institutions, 2008. http://proquest.umi.com/pqdweb?did=1666904001&sid=1&Fmt=2&clientId=1564&RQT=309&VName=PQD.

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29

Jackson, Brian Joshua. "Cognitive function and excessive daytime sleepiness in methamphetamine-dependent individuals." Diss., Restricted to subscribing institutions, 2008. http://proquest.umi.com/pqdweb?did=1679374131&sid=1&Fmt=2&clientId=1564&RQT=309&VName=PQD.

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30

Yingling, Julie Smith. "The relationship between social bond and frequency of methamphetamine use." Click here for download, 2008. http://proquest.umi.com/pqdweb?did=1490085051&sid=1&Fmt=2&clientId=3260&RQT=309&VName=PQD.

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31

Forrest-Lawrence, Pota. "Media, Policy and the Law: The Case of Crystal Methamphetamine." Thesis, The University of Sydney, 2016. http://hdl.handle.net/2123/15759.

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Crystal methamphetamine has been constructed by Australian media as the most dangerous illicit drug of the twenty-first century. Such representations, so readily available in print media commentary, have transformed the image of the drug from relative obscurity to a drug worse than heroin and a modern-day folk devil. Media calls for swift and urgent political action to address the methamphetamine problem have urged policymakers to respond to this ‘national drug threat’. This thesis explores the media construction of crystal methamphetamine, its users, manufacturers, importers and those who pol
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Northrop, Nicole Alia Fazo. "The role of neuroinflammation in stress & methamphetamine-induced damage." Thesis, Boston University, 2012. https://hdl.handle.net/2144/12543.

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Thesis (Ph.D.)--Boston University PLEASE NOTE: Boston University Libraries did not receive an Authorization To Manage form for this thesis or dissertation. It is therefore not openly accessible, though it may be available by request. If you are the author or principal advisor of this work and would like to request open access for it, please contact us at open-help@bu.edu. Thank you.<br>Methamphetamine (Meth) is a widely abused psychostimulant that causes damage to monoamine nerve terminals, marked by long-term depletions of dopamine (DA) and serotonin (5-HT), but the exact mechanisms by which
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33

Bardon, James. "A Phenomenological Study of Methamphetamine and Heroin Users’ Arrest Experiences." Diss., NSUWorks, 2018. https://nsuworks.nova.edu/cahss_jhs_etd/11.

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The costs in terms of both monetary and human lives lost due to substance abuse in the United States is well documented and it is publicized that it is increasing. There has been a large amount of research completed that has examined methamphetamine users, heroin users, and the drug-crime nexus; however, there is a paucity of research that provides insight into these users’ arrest experiences. Using a phenomenological approach, this research examined methamphetamine and heroin users’ incidents of being arrested to gain a greater understanding of their lived experiences. The analysis was based
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34

Wahl, Troy Andrew. "Developing Thyronamine Analog Pharmaceuticals Targeting TAAR1 to Treat Methamphetamine Addiction." PDXScholar, 2013. https://pdxscholar.library.pdx.edu/open_access_etds/1109.

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As a part of the overall program in the Grandy laboratory at Oregon Health & Science University (OHSU), studying the underlying chemical biology of methamphetamine (Meth) addiction, this dissertation reports on the development of six new thyronamine analogs which were synthesized and assayed against trace amine associated receptor 1 (TAAR1), giving preliminary results consistent with the analogs being inverse agonists. Due to highly variable TAAR1 expression levels in the assays, based on inter-assay response to control Meth stimulation as well as other possible factors, kinetic models were de
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35

Apollonio, Luigino Giuseppe, and n/a. "INNOVATIONS IN SYSTEMATIC TOXICOLOGICAL ANALYSIS: AMPHETAMINETYPE SUBSTANCES AND DESIGNER ANALOGUES." University of Canberra. Applied Science, 2007. http://erl.canberra.edu.au./public/adt-AUC20081030.110007.

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Recently, several novel technologies have emerged with substantial benefits in toxicological analysis. These include the development of beadbased multiplex immunoassay (Suspension Bead Array, SBA), the use of reduced-volume centrifugal ion-exchange extraction (SpinSPE), and Ultra-Performance (TM) liquid chromatographic separation coupled to mass spectrometry (UPLC(TM)/MS n ). This work sought to investigate the efficacy and practicality of these innovative approaches against a benchmark of established methods and instrumentation for the screening and confirmation of amphetaminetype substances.
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36

Prinsloo, Tarryn Kay. "In vitro effects of rooibos herbal tea (Aspalathus linearis) against methamphetamine on the mouse blood brain barrier." University of the Western Cape, 2014. http://hdl.handle.net/11394/4356.

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>Magister Scientiae - MSc<br>Methamphetamine (MA), also known as ‘Tik’, has detrimental short- and long-term psychological and morphological effects on the central nervous system (CNS). The lipophilic nature of MA allows it to cross the blood-brain barrier (BBB) which normally plays a protective role in limiting solute exchange (including narcotics) into the neuronal tissue. Numerous studies have indicated that MA not only crosses the BBB but is implicated in distorting its crucial role in that it increases the permeability of the endothelial cells and thereby compromises its core homeostatic
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Pike, Erika. "REINFORCING, SUBJECTIVE, AND COGNITIVE EFFECTS OF METHAMPHETAMINE DURING D-AMPHETAMINE MAINTENANCE." UKnowledge, 2013. http://uknowledge.uky.edu/psychology_etds/15.

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Translational research suggests that agonist replacement may be a viable treatment approach for managing methamphetamine dependence. This study sought to determine the effects of d-amphetamine maintenance on methamphetamine self-administration in stimulant using participants. A cognitive battery was used to determine the performance effects of methamphetamine alone and during d-amphetamine maintenance. During each maintenance condition, participants first sampled a dose of intranasal methamphetamine then had the opportunity to respond on a progressive ratio task to earn portions of the sampled
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38

Jones, Lashonda P. "Case menagers' perceptions of the association between methamphetamine and child neglect." DigitalCommons@Robert W. Woodruff Library, Atlanta University Center, 2008. http://digitalcommons.auctr.edu/dissertations/20.

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This study describes case managers' perceptions of the association between methamphetamine and child neglect. The analysis indicates that out of 30 women, 100.0% agreed that the use of methamphetamine is associated with child neglect. Children are being neglected due to methamphetamine causing impairment in the parents' ability to appropriately care for their children. The study findings note a statistically significant relationship between the variables at the .05 level of probability.
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Jauregui, Ana. "A study of methamphetamine and other illicit drug usage among youth." Thesis, California State University, Long Beach, 2014. http://pqdtopen.proquest.com/#viewpdf?dispub=1527713.

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<p> The purpose of this study was to examine the demographic differences in methamphetamine usage among youth and how methamphetamine users engaged in the use of other illegal drugs including, marijuana, cocaine, heroin, ecstasy and also engage in risk taking behaviors. The study utilized secondary data from the National Institute of Health, Youth Behavioral Risk Survey (YRBS) of20011. Sample size consisted of 294 both male and female youth who are methamphetamine users. The findings revealed that drug use amongst youth continues to be on the rise. Findings noted that male meth users had the h
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Lal, Ritu Anilkumar 1968. "Plasma protein binding and blood to plasma partitioning studies of methamphetamine." Thesis, The University of Arizona, 1991. http://hdl.handle.net/10150/277954.

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Methamphetamine is a sympathomimetic drug with CNS, cardiovascular and anorectic effects. We examined the Blood to Plasma (Blood/Plasma) partitioning and plasma protein binding (PB) of d-Methamphetamine (d-MAP), using whole rat blood. The mean Blood/Plasma ratio was around 1.2 and the fraction unbound (fᵤ) was 0.8. Further, we studied the influence of concentration, pH and the presence of 1-MAP on the Blood/Plasma ratio and PB of d-MAP. There was no significant change in the Blood/Plasma ratio and the PB values at different concentrations of d-MAP or in the presence of 1-MAP. There was a sligh
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Freeman, Carla Patricia. "White matter correlates of neuropsychological function in young adult methamphetamine users." Master's thesis, University of Cape Town, 2016. http://hdl.handle.net/11427/22762.

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Background: Methamphetamine (MA) abuse is a global health concern due to widespread use and harmful effects, which includes neurotoxicity. This study aimed to describe neurocognitive deficits associated with MA dependence in young adults and to explore whether these deficits correlate with white matter (WM) microstructural abnormalities using diffusion tensor imaging (DTI). Methods: Twenty-one MA dependent individuals recently enrolled in an outpatient rehabilitation program and nineteen healthy controls participated in the study. Each participant completed a neuropsychological evaluation and
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Burger, Antoinette. "Investigating the Influence of Methamphetamine on brain metabolism using 1H-MRS." Master's thesis, University of Cape Town, 2016. http://hdl.handle.net/11427/21000.

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Methamphetamine (MA) has been shown to have a detrimental relationship with on neuronal integrity and viability, and has been associated with decreased executive function. The association of acute and short-term MA abstinence on brain metabolism, in adult MA abusers, is understudied. Negative relationships with brain metabolism, cognitive development and executive functioning in prenatally MA exposed children are reported, however these studies are limited. The aim of this study was to investigate the relationship between MA and brain metabolism in adults after acute and short-term abstinence.
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Garvis, Pamela J. "Assessing methamphetamine withdrawal symptoms in the residential substance abuse treatment patient." Laramie, Wyo. : University of Wyoming, 2008. http://proquest.umi.com/pqdweb?did=1605148101&sid=1&Fmt=2&clientId=18949&RQT=309&VName=PQD.

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44

Vincent, Kathryn B. "The ecstasy and methamphetamine drug epidemics implications for prevention and control /." College Park, Md. : University of Maryland, 2005. http://hdl.handle.net/1903/3269.

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Thesis (M.A.) -- University of Maryland, College Park, 2005.<br>Thesis research directed by: Dept. of Criminology and Criminal Justice. Title from t.p. of PDF. Includes bibliographical references. Published by UMI Dissertation Services, Ann Arbor, Mich. Also available in paper.
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Chen, Mei-yin, and 陳美吟. "Development on Production of Antibodies against Methamphetamine and an Immunochromatographic Strip for Methamphetamine." Thesis, 2008. http://ndltd.ncl.edu.tw/handle/61964801770606585027.

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碩士<br>嘉南藥理科技大學<br>生物科技系暨研究所<br>96<br>Abstract Methamphetamine ( Meth ) is a drug that was initially synthesized to treat central nervous system ( CNS ) disorders such as schizophrenia. This psychostimulant has now become a major drug of abuse worldwide. In high doses, methamphetamine causes hyperactivity, agitation, hyperthermia, hypertension, cardiotoxicity and psychotic disorder such as paranoia. The objective of this study was to produce polyclonal antibody against methamphetamine. The antibody will be used for the application in the development of a nano-particle colloidal gold immunochrom
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"Methamphetamine and Novel "Legal High" Methamphetamine Mimetics: Abuse liability, Toxicity, and Potential Pharmacobehavioral Treatments." Doctoral diss., 2014. http://hdl.handle.net/2286/R.I.27393.

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abstract: Globally, addiction to stimulants such as methamphetamine (METH) remains a significant public health problem. Despite decades of research, no approved anti-relapse medications for METH or any illicit stimulant exist, and current treatment approaches suffer from high relapse rates. Recently, synthetic cathinones have also emerged as popular abused stimulants, leading to numerous incidences of toxicity and death. However, contrary to traditional illicit stimulants, very little is known about their addiction potential. Given the high relapse rates and lack of approved medications for
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47

Papageorgiou, Marco. "The Immunomodulatory Effects of Methamphetamine." Thesis, 2020. https://vuir.vu.edu.au/41838/.

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The psychostimulant, METH causes central nervous system damage, along with short and long-term changes to the innate and adaptive immune system. METH was investigated for its impact(s) across a range of physiological contexts. Specifically, crystal METH was investigated for its immune-modulatory effects, in cells of the innate immunity, as well as gene expression modifications in the mouse colon using open- source gene ontology programs. In this regard, changes in differential gene expression and subsequent enrichment in gene ontology groups allowed for a deeper understanding of how METH impac
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48

"Methamphetamine-induced neurotoxicity in cultured astrocytes." 1999. http://library.cuhk.edu.hk/record=b5889985.

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by Josephine Wing Sze Lau.<br>Thesis (M.Phil.)--Chinese University of Hong Kong, 1999.<br>Includes bibliographical references (leaves 84-112).<br>Abstracts in English and Chinese.<br>Acknowledgment --- p.iii<br>Abstract --- p.iv<br>List of Abbreviations --- p.viii<br>Chapter CHAPTER ONE: --- INTRODUCTION<br>Chapter 1.1 --- Methamphetamine (METH) --- p.1<br>Chapter 1.1.1 --- Historical Background and Epidemiology --- p.1<br>Chapter 1.1.2 --- Physical Effects of METH --- p.4<br>Chapter 1.1.3 --- Neurochemical Alternation of METH --- p.6<br>Chapter 1.2 --- Mechanisms of METH Toxicity<br>Ch
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49

Chiang, Chih-yuan, and 江致遠. "Anatomical Substrates of the Methamphetamine Memory." Thesis, 2008. http://ndltd.ncl.edu.tw/handle/39030262073261658667.

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碩士<br>國立成功大學<br>行為醫學研究所<br>96<br>Immunohistochemical Fos staining has proved to be a method to identify the loci of activated neurons specific to a stimulus. Although the methamphetamine (MA)-conditioned place preference (CPP) is a long-term memory, how and where the MA-CPP memory was stored and retrieved remained unknown. In this study, a conditioning procedure comprising of vehicle (saline) injection and previously-conditioned environment presentation, not performance test, was used as a way to reactivate the MA-CPP memory. Activated neurons in the limbic system following this MA-CPP memory
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50

"Methamphetamine: Examining Arizona's Drug Endangered Children." Master's thesis, 2011. http://hdl.handle.net/2286/R.I.8951.

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abstract: Children removed from methamphetamine laboratories are a severely understudied population despite the widespread deprivation parental methamphetamine abuse has on children, particularly in homes where methamphetamine is produced. Arizona's children are uniquely affected by the use and manufacturing of methamphetamine due to the geographic location and landscape of the state. A sample of 144 children removed from their homes during the seizure of methamphetamine laboratories, as part of the Arizona Drug Endangered Children program between 1999 and 2003, was investigated. Results indic
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