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Journal articles on the topic 'Methanol extract'

Author: Grafiati

Published: 4 June 2021

Last updated: 26 July 2025

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1

Karouche, S., S. Karouche, A. Benbott, et al. "Evaluation of phenolic content and biological activities of Bunium mauritanicum tuberss." Journal of Fundamental and Applied Sciences 12, no. 2 (2023): 916–30. http://dx.doi.org/10.4314/jfas.v12i2.27.

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The present work is carried out to evaluate biological activities of tubers extracts of Bunium mauritanicum. The methanol extract yield had higher (7.81%) tha n that of the aqueous extract (6.79%). The quantitative analysis of total phenols and flavonoid revealed that the highest concentration was recorded for the methanoic fraction with 89,442 ± 5,951μg EAG mg and 4.031 ± 0.141 μg EQ mg of extract respectively. In addition, the aqueous extract of tubers represents the most important antioxidant activity with an IC 50 of 0.14 mg ml against 2,2 diphenyl 1 picryl hydrazyl (DPPH Wherea s, the two

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2

Sapkota, Sujana, Alishma Maharjan, Sanjeeta Tiwari, and Meena Rajbhandari. "Phytochemical Analysis, Antioxidant Potential and Antibacterial Activities of Different Anatomical Parts of Hypericum cordifolium Choisy." Scientific World Journal 2024 (May 25, 2024): 1–11. http://dx.doi.org/10.1155/2024/8128813.

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The genus Hypericum comprises a large number of species. The flower, leaf, stem, and root of the Hypericum species are widely used in traditional medicine in different cultures. Many Hypericum species have been well investigated phytochemically and pharmacologically. However, only a few reports are available on the H. cordifolium native to Nepal. The present study aims to evaluate the phytochemical composition of different extracts, qualitative analysis of methanol extract of the flower and leaf using thin-layer chromatography (TLC), and the antioxidant properties of components by the TLC-DPPH

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3

Paneru, Damaru Prasad, and Meena Rajbhandari. "Phytochemical Analysis and Antimicrobial Activity of Smilax ovalifoliaRoxb. Ex D. Don." Nepal Journal of Science and Technology 19, no. 1 (2020): 89–96. http://dx.doi.org/10.3126/njst.v19i1.29787.

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Hexane, dichloromethane, ethyl acetate, methanol and 50% aqueous methanol extracts of S. ovalifoliawere screened for the presence of different classes of phytochemicals as well as their antibacterial activity. The phytochemical screening revealed the presence of phenolic, flavonoid and carbohydrate in methanol and 50% aqueous methanol extracts of S. ovalifolia. The antibacterial susceptibility was studied against E. coli and S. aureus. Among all the tested extracts, ethyl acetate extract showed good antibacterial activity against both bacteria. In the methanol and 50%, aqueous methanol extract

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4

Aslam, Bilal, and Asif Hussain. "Phytochemical Characterization and Solvent Fraction Depending in vitro Antioxidant Activities of Cassia absus, Gymnema sylvestre, Nigella sativa and Piper nigrum." Revista de Chimie 72, no. 2 (2021): 38–49. http://dx.doi.org/10.37358/rc.21.2.8418.

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This study was aimed to phytochemically characterize and assess the antioxidant activities of 70% methanol extract and subsequent fractions of Cassia absus (L.) seeds, Gymnema sylvestre (L.) whole plant, Nigella sativa (L.) seeds, and Piper nigrum (L.) seeds. Powdered plant materials were extracted with 70% methanol and further fractionated with ethyl-acetate, n-butanol and the residual aqueous fraction. Phytochemical analysis was performed to detect different phytocompounds. Mineral compositions were quantified, and total phenolic and flavonoid contents were determined. The antioxidant potent

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5

Kafle, Saroj, Ram Chandra Basnyat, and Meena Rajbhandari. "Phytochemical Analysis, Antioxidant, Antimicrobial Activities and GC-MS Profiling Of Drymaria Diandra Blume." Scientific World 14, no. 14 (2021): 90–98. http://dx.doi.org/10.3126/sw.v14i14.35000.

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Drymaria diandra is used in Nepalese traditional medicine to treat various ailments. The hexane, dichloromethane, ethyl acetate, methanol and 50% aqueous methanol extracts of D. diandra were prepared and screened for the presence of different classes of phytochemicals. Methanol and 50% aqueous methanol extracts showed the presence of phenolics, flavonoids and carbohydrates so their total contents were estimated. The highest amount of phenolics and flavonoids were found in methanol extract (190.58±2.21 mg GAE/g extract and 69.25±7.91 mg CE/g extract respectively). The highest amount of sugar wa

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6

Rohman, Abdul, and Sugeng Riyanto. "Aktivitas Antioksidan Ekstrak Buah Mengkudu (Morinda citrifolia, L)." agriTECH 25, no. 3 (2017): 131. http://dx.doi.org/10.22146/agritech.13347.

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This research aimed to determine antioxidant activity of Morinda citrifolia, L fruit extracts. Morinda citrifolia, L fruit was ground, extracted by methanol, and partitioned by using chloroform and ethyl acetate to recover extracts of methanol, chloroform and ethyl acetate respectively. These extracts were diluted to various concentrations i.e. 1, 5, and 10 %, and were determined their antioxidant activities by linoleic-thiocyanate method. The result showed that extracts of Morinda citrifolia, L fruit had antioxidant activity in the order of ethyl acetate extract > chloroform extract > m

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7

Giri, Dil Prakash, and Meena Rajbhandari. "PHYTOCHEMICAL ANALYSIS AND CONSTITUENTS OF HEXANE EXTRACT OF MELASTOMA MALABATHRICUM L." Journal of Institute of Science and Technology 23, no. 1 (2018): 18–25. http://dx.doi.org/10.3126/jist.v23i1.22150.

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Hexane, dichloromethane, ethyl acetate, methanol and 50 % aqueous methanol extracts of leaf, flower and fruit of Melastoma malabathricum were screened for the presence of different classes of phytochemicals. In phytochemical screening, ethyl acetate, methanol and 50 % aqueous methanol extracts showed the presence of phenolics and flavonoids. Glycosides were found only in the 50 % methanol extract of fruit. Free radical scavenging activity of methanol extract of leaf, flower and fruit was determined using 2,2-Diphenyl-1-picrylhydrazyl (DPPH) free radical. Total phenolic content was measured spe

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8

Kinjal H, Dr Shah. "Evaluation of Antioxidant Activity of Balanites Roxburghii Planch. Fruit Extracts." International Journal of Scientific Research and Management (IJSRM) 7, no. 12 (2019): 295–304. http://dx.doi.org/10.18535/ijsrm/v7i12.mp03.

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Antioxidant potency of fruits of Balanites roxburghii Planch.crude methanol and its fractionated extracts (hexane, ethyl acetate, methanol and water) have been investigated, employing three different established in vitro testing systems, such as scavenging activity on 1,1-diphenyl-2-picrylhydrazyl (DPPH) radicals, reducing power assay and β-carotene method. The methanol extract of fruits of Balanites roxburghii Planch.showed the best DPPH scavenging activity with the lowest EC 50 34 μg/ml, followed by the ethyl acetate (EC 50 39 μg/ml), hexane (EC 50 48 μg/ml) and water extract (EC 50 54 μg/ml

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9

Mahboubi, Mohaddese, Nastaran Kazempour, Hossein Hosseini, and Mona Mahboubi. "Antimicrobial and antioxidant activity of Epimedium pinnatum." Herba Polonica 59, no. 2 (2013): 24–34. http://dx.doi.org/10.2478/hepo-2013-0009.

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Summary Epimedium pinnatum (Berberidaceae family) is used as an aphrodisiac in traditional Chinese medicine (TCM). The aim of this study was to evaluate the antimicrobial and antioxidant activity of E. pinnatum extracts (ethanol, methanol and aqueous extracts). Total phenolic (TPC) and flavonoid contents (TFC) of each extract were assessed by spectrophotometric methods. It was exhibited that methanol extract had better antimicrobial activity than those of ethanolic extract or aqueous extract. The TPC and TFC of E. pinnatum extracts was higher in methanol extract (149 and 36.6 mg/g) than that o

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10

Sureshkumar, V., S. Rajagunalan, and S. Malmarugan. "An in vitro evaluation of antibacterial activity of various extracts of Achyranthes aspera and Cissus quadrangularis." INTERNATIONAL JOURNAL OF AGRICULTURAL SCIENCES 17, no. 2 (2021): 365–70. http://dx.doi.org/10.15740/has/ijas/17.2/365-370.

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The antibacterial activity of aqueous and methanol extracts of Achyranthes aspera and Cissus quadrangularis was evaluated. A. aspera and C. quadrangularis plants collected from its natural habitat in and around Tirunelveli, Tamil Nadu, India were shadow dried at room temperature and pulverized into coarse powder. Aqueous extracts were prepared by extracting with distilled water at 100°C for 4h and methanol extracts were prepared by maceration process using methanol for 72h. The aqueous extract yield was 12.1% and 23.5% for A. aspera and C. quadrangularis respectively. Whereas, methanol extract

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11

C, Nwokonkwo Dorothy. "UTILIZATION OF AQUEOUS, METHANOL AND CHLOROFORM EXTRACTS OF LOCAL PLANTS- IXORA COCCINEA AND HIBISCUS SABDARRIFFA (ZOBO) FROM ABAKALIKI AS FABRIC DYES." JOURNAL OF ADVANCES IN CHEMISTRY 11, no. 5 (2015): 3576–82. http://dx.doi.org/10.24297/jac.v11i5.4476.

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This investigation dealt with the dyeing and fastness properties of crude constituents of Ixora coccinea and Hibiscus sabdarriffa plant species extracted using distilled water, methanol and chloroform. Approximately 150 g of each sample was soaked in the chosen solvent for four weeks, the percentage yields of the aqueous, methanol and chloroform extracts of Ixora coccinea were 38.47% and 13.40 % and 3.88 % respectively; Hibiscus sabdariffa gave yields of 22.85 % for the aqueous extract, 12.24 % for the methanol extract and 3.79 % for the chloroform extract. Aqueous, methanol and chloroform ext

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12

Chaudhary, Umesh, and Meena Rajbhandari. "Phytochemical analysis, antioxidant and antimicrobial activities of Ammannia baccifera L." Scientific World 18, no. 18 (2025): 128–34. https://doi.org/10.3126/sw.v18i18.78443.

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Ammannia baccifera has wide application in ethnomedicine around the globe and it has been investigated for various pharmacological activities. However, A. baccifera from Nepal is not investigated phytochemically and biologically. Here we report about the screening of extracts for phytochemicals, estimation of phenolics, flavonoids, tannins and sugars as well as antioxidant and antibacterial activities of different extracts. In phytochemical screening, phenolics, flavonoids, glycosides, saponins, quinones, reducing sugar, tannins, steroids and coumarin were detected in methanol and 50% aqueous

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13

Poudel, Madhav, and Meena Rajbhandari. "Phytochemical Analysis of Ampelopteris Prolifera (Retzius) Copeland." Nepal Journal of Science and Technology 19, no. 1 (2020): 78–88. http://dx.doi.org/10.3126/njst.v19i1.29786.

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The fronds of Ampelopteris prolifera are used in stomach ache as well as vegetable. Dried and powdered fronds of A. prolifera was extracted successively with hexane, chloroform, ethyl acetate, methanol and 50% aqueous methanol. The results of phytochemical screening revealed that alkaloids were absent in all extracts. Hexane extract showed the absence of all the tested phytochemicals while chloroform extract showed the presence of only terpenoids and quinones. Ethylacetate extract showed the presence of all tested phytochemicals except quinones and saponins.Methanol and 50% aqueous methanol ex

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14

Idris, Musa Maikudi, Adamu Mohammed Yelwa, and Aminu Muhammad. "Phytochemical Screening, Cytotoxicity and Antioxidant Activities of Leaves Extracts from Eucalyptus citriodora." Journal of Tropical Pharmacy and Chemistry 5, no. 3 (2021): 165–73. http://dx.doi.org/10.25026/jtpc.v5i3.280.

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The genus Eucalyptus has been used in African traditional medicine for the treatment of cardiovascular diseases and diabetes. In this work, chloroform and methanol extracts from the leaves of Eucalyptus citriodora was investigated for their phytochemicals, cytotoxicity and antioxidant potentials. Phytochemical screening of the extracts showed the presence of alkaloid, flavonoid, phenols, reducing sugar and steroids in the methanol extract. IR absorptions of the extract supported the presence of these phytochemicals by revealing the bands 3335 cm-1 (O-H), 1613, 1480 cm-1 (C=C) and 1721 cm-1 (C=

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15

Hidayati, Mutia Devi, Taslim Ersam, Kuniyoshi Shimizu, and Sri Fatmawati. "Antioxidant Activity of Syzygium polyanthum Extracts." Indonesian Journal of Chemistry 17, no. 1 (2017): 49. http://dx.doi.org/10.22146/ijc.23545.

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Antioxidant activities of Syzygium polyanthum leaves extracts (methanol, ethyl acetate, dichloromethane and n-hexane) were evaluated by using DPPH (2,2-diphenyl-2-picrylhydrazyl) and ABTS (2,2’-azinobis (3-ethylbenzothiazole-6-sulfonic acid) methods. The methanol extract showed the highest antioxidant activity of DPPH assay among extract with IC50 value of 44.35 mg/mL. In addition, methanol extract also showed the highest antioxidant activity of ABTS assay among extracts with IC50 value of 17.69 mg/mL. This study indicated that the methanol extract of S. polyanthum leaves is potential as antio

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16

Mahboubi, Mohaddese, Atefeh Mahboubi, and Nastaran Kazempour. "The antimicrobial activity of Prunella vulgaris extracts." Herba Polonica 61, no. 1 (2015): 31–38. http://dx.doi.org/10.1515/hepo-2015-0008.

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Summary Prunella vulgaris ( Labiatae family) or self-heal is traditionally used for different ailments such as eye pain and inflammation, headache, dizziness, sore throat and wound healing. Total phenolic and total flavonoid contents of extracts (methanol, ethanol and aqueous) were determined by a spectrophotometer. The antimicrobial activity was evaluated by micro broth dilution assay. The total phenolic content of P. vulgaris extracts were higher in aqueous extract (156.5 mg GAC/g) followed by ethanol extract and methanol extract. The TFC content of P. vulgaris methanol extract (82.8 mg QE/g

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17

Maffo Tazoho, Ghislain, Esther Etengeneng Agbor, and Inocent Gouado. "In vitro, antioxidant activities of aqueous and methanol roselle (Hibiscus sabdariffa) calyces extracts from two localities in Cameroon." North African Journal of Food and Nutrition Research 4, no. 08 (2020): 292–97. http://dx.doi.org/10.51745/najfnr.4.08.292-297.

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Background: Fighting against malnutrition and diseases such as oxidative stress diseases via a food-based approach could be achieved through identification, valorization, and promotion of local foods rich in macro- and micronutrients and phytochemical components. Aim: This study aimed to investigate the effect of agro-ecological conditions on the antioxidant capacity of the Hibiscus sabdariffa aqueous and methanol calyces extracts. Material and methods: The total phenolic content, the free radical DPPH• (1,1-diphenyl-2-picrylhydrazyl), and ferric reducing antioxidant power (FRAP) activities we

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18

Tazoho, Ghislain Maffo, Esther Etengeneng Agbor, and Inocent Gouado. "In vitro, antioxidant activities of aqueous and methanol roselle (Hibiscus sabdariffa) calyces extracts from two localities in Cameroon." North African Journal of Food and Nutrition Research 4, no. 8 (2020): 292–97. http://dx.doi.org/10.51745/najfnr.4.8.292-297.

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Background: Fighting against malnutrition and diseases such as oxidative stress diseases via a food-based approach could be achieved through identification, valorization, and promotion of local foods rich in macro- and micronutrients and phytochemical components. Aim: This study aimed to investigate the effect of agro-ecological conditions on the antioxidant capacity of the Hibiscus sabdariffa aqueous and methanol calyces extracts. Material and methods: The total phenolic content, the free radical DPPH• (1,1-diphenyl-2-picrylhydrazyl), and ferric reducing antioxidant power (FRAP) activities we

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19

Turkmen, Filiz Ucan, Fatma Esen Sarigullu Onalan, and Hatice Aysun Mercimek Takci. "Antioxidant activities of pomegranate peel methanolic and water extracts by in vitro methods." Natural Science and Discovery 4, no. 1 (2021): 1–6. http://dx.doi.org/10.20863/nsd.v4i1.59.

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In this study, the antioxidant activities of pomegranate (Punica granatum) peel extracts were investigated using different antioxidant activity methods. The antioxidant activities of extracts prepared at different concentrations (100-1000 μg/ml) were compared with α-tocopherol, ascorbic acid, BHT, and BHA standards. The methanol extract of peels had the highest yield (45.5%). Chelating activities (Fe2+) of methanol extract at 100-1000 μg/ml concentrations ranged between 16.63 and 46.45%. However, the chelating activities of all test extracts were lower than the standards. The reducing power of

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20

Lee, Hyun-Hwa, Jin-Sol Kim, Jun-Han Jeong, Sook-Young Lee, and Chun-Sung Kim. "Comparative Analysis of Biological Activities and Phenolic Content between Fresh and Steamed Sargassum fusiforme in Different Extraction Solvents." Applied Sciences 12, no. 23 (2022): 12161. http://dx.doi.org/10.3390/app122312161.

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Sargassum fusiforme (SF), a perennial brown, is often steamed for consumption. SF contains many bioactive compounds; however, the effect of steaming these compounds is unknown. This study investigates phenolic component contents and antioxidant and antiaging activities of fresh (SF) and steamed (SSF) extracts in different solvents (95% ethanol, 95% methanol, hot water). Total polyphenol and flavonoid content was highest in SSF methanol (9.76 mg TAN/g) and SF methanol extracts (13.42 mg QUE/g). The DPPH radical scavenging activity was highest in SF methanol extracts (IC50 = 5.83 μg/μL), whereas

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21

Oyeleke, Oyedotun, Mutiat Bamigboye, Boyede Olowookere, Kehinde Alabi, Samuel Oladele, and Johnson Oladele. "Comparative Studies on the Phytochemical Constituents and in vitro Antioxidant Activities of Methanol and Ethyl Acetate Leaf Extracts of Talium Trangulare." Journal of Basic and Applied Research in Biomedicine 7, no. 1 (2021): 18–23. http://dx.doi.org/10.51152/jbarbiomed.v7i1.209.

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Medicinal herbs have been known for their use as an alternative medicine in the management and treatment of different categories of diseases. The present study was designed to assess the phytochemical constituents present in methanol and ethylacetate leaves extract of Talium trangulare and its antioxidant potentials against free radicals comparatively. The functional groups of the phytochemicals were carried out using FTIR techniques while the phytochemical component of the extract was determined by standard methods. The comparative studies of antioxidant abilities of methanol and ethylacetate

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22

Lenny, Sovia, Murni Suryani Lumbantoruan, and Helmina Br Sembiring. "Antioxidant Activity Assay of Eucalyptus pellita Leaf Extract." International Journal of Ecophysiology 5, no. 2 (2023): 26–33. http://dx.doi.org/10.32734/ijoep.v5i2.13715.

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In pharmacy, eucalyptus leaves are used for various pharmacological activities because they contain phenolic compounds. This study aims to detect phytochemical compounds and test the antioxidant activity of Eucalyptus pellita leaf extract. The dry powder of E. pellita leaves (1900 g) was macerated first with methanol solvent. The concentrated methanol extract was then subjected to partition extraction with n - hexane solvent. The methanol layer was concentrated and then partitioned with ethyl acetate solvent. Methanol extract was obtained as much as 176.75 g (9,30%), n-hexane extract 13.77 g (

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23

TASKIN, Turgut, Murat DOGAN, Muhammet E. CAM, Talip SAHIN, and Ismail SENKARDES. "In vitro anti-urease, antioxidant, anticholinesterase, cytotoxic and in vivo anti-inflammatory potential of Satureja cuneifolia Ten." Notulae Scientia Biologicae 12, no. 2 (2020): 222–32. http://dx.doi.org/10.15835/nsb12210687.

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Satureja cuneifolia Ten. (wild savoury) belongs to the Lamiaceae family and is used to produce essential oil and aromatic water. This plant is also used as a condiment and herbal tea due to its stimulating, tonic and carminative effects. The in vitro antioxidant, anti-urease, anticholinesterase and cytotoxic activities of the different extracts from the plant’s aerial parts were examined. Besides, the in vivo anti-inflammatory activities of the fraction and direct methanol extracts were determined comparatively. In the current study, fraction methanol extract exhibited the strongest ABTS (52.3

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24

Banik, SK, S. Iftekhar, AFMM Rahman, ML Bari, and MS Islam. "Bioactive potential of Aphanamixis polystachya seed extracts." Bangladesh Journal of Scientific and Industrial Research 56, no. 2 (2021): 75–86. http://dx.doi.org/10.3329/bjsir.v56i2.54314.

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Aphanamixis polystachy seed extracts were examined for their in-vitro biological activities. The n-hexane and methanol extract showed significant phenolic content of 12.0 and 11.7 mg GAE/g, respectively. Antioxidant activity was exhibited by the methanol extract (IC50: 22.34 μg/mL) and moderate activity was shown by the n-hexane extract (IC50: 63.05 μg/ml) compared to BHT (tert-butyl-1- hydroxy toluene, IC50: 14.01 μg/ml) though both extracts caused moderate clot lysis of 18.84% and 23.49% compared to the positive control Streptokinase (65.16%). The n-hexane and methanol extract had shown 18.2

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25

Nabilah, Almurdani M., Rudi Hendra, and Hilwan Yuda Teruna. "Antioxidant activities of medang lendir (Litsea glutinosa) stem bark." Pharmacy Education 23, no. 2 (2023): 122–25. http://dx.doi.org/10.46542/pe.2023.232.122125.

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Background: Medang lendir (Litsea glutinosa), a member of the Lauraceae family, is typically found in the Kampar Regency area of Riau Province, Indonesia. This plant is frequently used in traditional medicine to treat rheumatism, diarrhea, and dysentery. Objective: To evaluate the antioxidant activities of L. glutinosa stem bark extracts. Method: L. glutinosa stem bark was macerated in methanol to obtain methanol extract, followed by partitioning with ethyl acetate to obtain ethyl acetate extract. The antioxidant activities of these extracts were determined using the NO radical scavenging and

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26

Rajendrasozhan, Saravanan, Hani El Moll, Mejdi Snoussi, et al. "Phytochemical Screening and Antimicrobial Activity of Various Extracts of Aerial Parts of Rhanterium epapposum." Processes 9, no. 8 (2021): 1351. http://dx.doi.org/10.3390/pr9081351.

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Rhanterium epapposum, native to the Arabian Peninsula, is traditionally used to cure skin infections. The objective is to screen the phytochemical content and antimicrobial activity of aqueous, methanol and 80% methanol extracts of aerial parts of R. epapposum. The phytochemical screening of aqueous, methanolic, and 80% methanol extracts of R. epapposum was conducted using gas chromatographymass spectrometry. The antimicrobial activities of the extracts were assessed by well diffusion and microdilution methods. Qualitative phytochemical analysis revealed the presence of 2-methoxy-4-vinylphenol

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Ahmed, F., MB Meah, and F. Yasmin. "Isolation of Phomopsis Inhibitory Fraction of Allamanda Extract Removing Gum and Other Undesirable Compounds." Journal of Environmental Science and Natural Resources 5, no. 2 (2013): 199–203. http://dx.doi.org/10.3329/jesnr.v5i2.14814.

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Allamanda leaf extracts were made by three organic solvents hexane, methanol and ethyl acetate having different polarities. Thin layer chromatography (TLC) of the refluxing extracts showed each of them contained considerable number of different compounds. By observing Rf value of these extracts it was confirmed that the compounds present in different extracts are not same and two of them (methanol and ethyl acetate) extracts were distilled to remove solvent for bioactivity test. In growth inhibition test, methanol and ethyl acetate extracts of allamanda inhibited mycelial growth of Phomopsis v

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Hernández-Fernández, Adrián, Yolanda Garrido, Eduardo Iniesta-López, Antonia Pérez de los Ríos, Joaquín Quesada-Medina, and Francisco José Hernández-Fernández. "Recovering Polyphenols in Aqueous Solutions from Olive Mill Wastewater and Olive Leaf for Biological Applications." Processes 11, no. 9 (2023): 2668. http://dx.doi.org/10.3390/pr11092668.

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Olive leaf and olive mill wastewater are wastes which are produced in olive industry and can be used to obtain value-added products such as polyphenols. In this work, extracts of polyphenols from olive mill wastewater and olive leaf in an aqueous medium are obtained and their composition in polyphenols were determined and compared with those obtained using the conventional extract agent (methanol–water). The antioxidant capacity of the aqueous extracts of olive mill wastewater and olive leaf were also analysed. It was observed that the olive mill wastewater extracted in water provides a simila

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AŞKIN ÇELİK, Tülay, and Özlem Sultan ASLANTÜRK. "Phytochemical screening and in vitro assessments of antioxidant and cytotoxic potentials of extracts from Aesculus hippocastanum L. green fruit mesocarps." International Journal of Secondary Metabolite 10, no. 2 (2023): 245–56. http://dx.doi.org/10.21448/ijsm.1139025.

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In this study, the in vitro antioxidant and cytotoxic effects of water and methanol extracts obtained from the green fruit mesocarp of Aesculus hippocastanum L. (Hippocastanaceae) were investigated. Phytochemical content of the methanol extract and the water extract were determined by qualitative methods; antioxidant activity was determined by DPPH free radical scavenging test, and total antioxidant capacity was determined by phosphomolybdate test. The effects of the extracts on proliferation and cell viability of BJ normal human foreskin fibroblasts were also evaluated by the WST-8 cell viabi

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30

Jaishwal, Nitesh, Mamta Jayswal, Deep Chand Gupta, et al. "Bioactive Potential of Pogostemon benghalensis (Burm.f.) Kuntze: Antibacterial, Antioxidant, and Xanthine Oxidase Inhibitory Activities." Bacteria 4, no. 1 (2025): 3. https://doi.org/10.3390/bacteria4010003.

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This research is focused on assessing the antibacterial properties of Pogostemon benghalensis stem bark and inflorescence extracts, as well as their inhibitory effects on xanthine oxidase, antioxidant potential, overall phenolic content, and flavonoid concentration. The cold maceration technique was used to obtain extracts using water, methanol, and ethyl acetate solvents. The disk diffusion method demonstrated the significant antibacterial efficacy of the methanol stem bark extract against Staphylococcus epidermidis, with a zone of inhibition (ZOI) of 13 mm, and the inflorescence methanol ext

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31

Delporte, Carla, Orlando Muñozb, Javier Rojas, et al. "Pharmaco-Toxicological Study of Kageneckia oblonga, Rosaceae." Zeitschrift für Naturforschung C 57, no. 1-2 (2002): 100–108. http://dx.doi.org/10.1515/znc-2002-1-218.

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The probable antipyretic, antiinflammatory, analgesic and antioxidant properties of Kageneckia oblonga, Rosaceae, were investigated and the major compounds of its active extracts were isolated. The study comprised the acute toxicity of the extracts of global methanol, hexane, dichloromethane and methanol. The cytotoxicity of global methanol extract was studied in three tumoral cell lines. All the extracts exhibited the pharmacological activities under study. Methanol and dichloromethane were the most toxic extracts. From the global methanol extract, isolations were performed of prunasin, 23,24

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Elhag, E. A., A. H. El Nadi, and A. A. Zaitoon. "Ovipositional Deterrence of Methanolic and Etherial Extracts of Five Plants to the Cowpea Bruchid, Callosobruchus maculatus (F.) (Coleoptera: Bruchidae)." Journal of Agricultural and Marine Sciences [JAMS] 4, no. 2 (1999): 27. http://dx.doi.org/10.24200/jams.vol4iss2pp27-33.

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Methanol and diethyl ether extracts of Harmal, Rhazya stricta Decne.; neem seed kernels, Azadirachta indica A.Juss; cloves, Syzygeum aromarticum (L.); citrus peel and Ramram, Heliotropium bacciferum (Forssk-) were evaluated for their deterrence to oviposition by Callosobruchus maculatus (F.) on chickpeas in choice tests. Both extracts of all materials significantly reduced oviposition on treated seeds. Maximum deterrent effects (91.8%) were obtained in the neem seed methanol extract at 0.5% concentration, citrus peel O. l% ether extract (90.9%), R stricta 0.5% methanol extract (83.9%), and clo

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Touaibia, Meriem, and Abdellali Dhoha. "Biochemical characterization, antioxidant and antidiabetic properties of <i>Zygophyllum geslini</i> Coss extracts." International Journal of Biological and Chemical Sciences 18, no. 3 (2024): 1105–14. http://dx.doi.org/10.4314/ijbcs.v18i3.30.

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Zygophyllum geslini Coss. is a medicinal plant growing wild in the northern Sahara of Algeria, belonging to Zygophyllaceae family. The objective of this study was to evaluate some biochemical properties of the aqueous lyophilized extract and the methanol leaf extracts of this plant, their antioxidant and antidiabetic activities were also tested. The content of total phenols, flavonoids and tannins detected in the methanol extract (183.22 mg Gallic acid equivalent/g Dry Extract, 101.13±0.02 mg Quercetin equivalent /g Dry Extract, 54.07±0.98 mg Tannic acid equivalent/g Dry Extract respectively)

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Ergün, Fatma. "Cotoneaster transcaucasicus Pojark. Meyve Ekstraklarında Biyoaktif Bileşen Miktarlarının ve Antioksidan Aktivitelerinin Belirlenmesi." Turkish Journal of Agriculture - Food Science and Technology 9, no. 7 (2021): 1258–63. http://dx.doi.org/10.24925/turjaf.v9i7.1258-1263.4432.

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In this study, the total phenolic and flavonoid contents and antioxidant activities of hexane and methanol extracts of Cotoneaster transcaucasicus Pojark. fruits in the Rosaceae family were investigated. Using the Folin-Ciocaltaeu method, the amount of phenolic substances was determined as 50.34 ± 2.70 mg of GAE/g in methanol extract and 38.06 ± 1.32 mg of GAE/g in hexane extract. The total amount of flavonoids was calculated as 52.01 ± 3.78 mg of QE/g in the methanol extract and 60.54 ± 6.82 mg of QE/g in the hexane extract, using the aluminum nitrate method. Antioxidant activities of C. tran

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M. Andi Chandra, M. Hidayatullah Hidayatullah, and Putri Ermina Sari Putri. "Perbandingan Rendemen, Skrining Fitokimia Dan Profil Kromatografi Lapis Tipis Ekstrak Etanol 96% dan Metanol Daun Sungkai (Peronema canescens Jack)." Jurnal Kesehatan Islam : Islamic Health Journal 12, no. 2 (2023): 48–54. http://dx.doi.org/10.33474/jki.v12i2.20818.

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Abstract. Kalimantan is rich in plants that are used as medicinal plants, one of which is the sungkai plant (Peronema canescens Jack). The aim of this research was to determine the comparison of yields of different solvent extracts and the comparison of phytochemical screening results and TLC profiles of 96% ethanol and methanol extracts. Extraction was carried out by maceration, then phytochemical screening and stain profiles were carried out using the thin layer chromatography (TLC) method using the mobile phase N-Hexane and Ethyl Acetate (8:2). The results of the research showed that the ra

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Wang, Jing, Jian Li, and Shu Jun Li. "Components of Cunninghamia lanceolata Heartwood Extracts." Materials Science Forum 685 (June 2011): 188–94. http://dx.doi.org/10.4028/www.scientific.net/msf.685.188.

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China-fir (Cunninghamia lanceolata) has a reputation for producing naturally durable heartwood. This species is native in China and has been extensive planted there. Mainly, extractives are responsible for the wood resistance to decay fungi. Compared with the number of studies on China fir focused only on essential oil, studies on other China fir wood extracts is few. In this report, different Cunninghamia lanceolata heartwood extracts were studied. Ground wood was sequentially extracted by solvents with different polarities, hexane, ethyl acetate and methanol. The components of the extracts w

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CHAITHADA, Prakit, Juthamas SUPAPAN, Juthamas SUPAPAN, et al. "Total Flavonoids, Total Phenolic Content and Antioxidant Activity from Fruits, Leaves, Twigs and Flowers of Mesua ferrea L." Walailak Journal of Science and Technology (WJST) 15, no. 4 (2018): 295–304. http://dx.doi.org/10.48048/wjst.2018.3946.

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The objective of this study was to compare antioxidant activity from crudes of fruits, leaves, twigs and flowers of Mesua ferrea L. with hexane, dichloromethane and methanol by controlling time and temperature in the solvent extraction. All crude extracts were investigated for their antioxidant capacity in 1,1-diphenenyl-2-picryhydrazyl (DPPH) radical scavenging. The results indicated that the high polar solvent exhibited the highest DPPH radical scavenging activity. The methanol extracts of leaves show the highest activity with IC50 of 89.94±0.65 μg/mL. The flowers, twigs and fruits methanol

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Touaibia, Meriem, and Dhoha Abdellali. "Antioxidant properties of the endemic plant Zygophyllum cornutum (Zygophyllaceae) extracts." Acta Scientifica Naturalis 12, no. 1 (2025): 1–14. https://doi.org/10.2478/asn-2025-0002.

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Abstract Zygophyllum cornutum is a plant growing in the northern Sahara of Algeria, belonging to Zygophyllaceae family. The antioxidant activities of four organic extracts (aqueous lyophilized extract, methanol extract, butanol extract and cyclohexane extract) of Z. cornutum leaves were investigated by DPPH test, ferric reducing activity and scavenging of superoxide radical (NBT test). In addition, polyphenols, flavonoids, tannins and anthocyanins were estimated by spectrophotometric methods. The content of total phenols, flavonoids and tannins is highly detected in the methanol extract (183.2

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Sivakumari, K. "PHYTOCHEMICAL PROFILING, ANTICANCER AND APOPTOTIC ACTIVITY OF GRAVIOLA (ANNONA MURICATA) FRUIT EXTRACT AGAINST HUMAN HEPATOCELLULAR CARCINOMA (HepG-2) CELLS." International Journal of Zoology and Applied Biosciences 5, no. 1 (2020): 32–47. https://doi.org/10.5281/zenodo.3735733.

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To examine the phyto-constituents present in A. muricata fruit pulp, and to assess the anticancer potential followed by apoptotic studies on HepG-2 cell line. Aqueous, Chloroform, Ethyl acetate, Hexane and Methanol extracts of dragon fruit pulp were analysed by qualitative phytochemical profiling and anti-proliferation activity. Further, the apoptotic study of methanol extract treated HepG-2 cells by nuclear staining using AO, DNA fragmentation, ATR and GC-MS spectral analysis for methanol extract was carried out. The preliminary phytochemical screening showed the presence of acids, alkaloids,

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Asita, Asita Okorie, Sibusisiwe Magama, Thato Mamoroesi Moahloli, and Selometsi Baholo. "Evaluation of extracts of wild Cannabis sativa L. for genotoxicity and phytochemical composition." Caryologia 74, no. 1 (2021): 135–50. http://dx.doi.org/10.36253/caryologia-1041.

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Cannabis sativa L. is used as medicine and narcotic in Lesotho. Phytochemical composition and total phenolics content (TPC) for hexane, chloroform, ethyl acetate and methanol extracts of aerial parts of C. sativa were determined. Ethyl acetate extract (0.1875, 0.375 and 0.75 mg mL-1) and methanol extract (0.75, 1.5 and 3.0 mg mL-1) were evaluated for cytotoxicity, genotoxicity and modulation of cyclophosphamide (CP, 1.25 mg mL-1)- and ethylmethane sulphonate (EMS, 0.25 mg mL-1)-induced genotoxicity using Allium cepa root meristem assay. CP or EMS did not reduce mitotic index (MI) of cells, hen

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Pandey, Bedraj, and Meena Rajbhandari. "Estimation of Total Phenolic and Flavonoid Contents in Some Medicinal Plants and Their Antioxidant Activities." Nepal Journal of Science and Technology 15, no. 1 (2015): 53–60. http://dx.doi.org/10.3126/njst.v15i1.12010.

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Quercetin was isolated from ethyl acetate fraction of a methanol extract of the outer scale of onion by repeated sephadex LH-20 column chromatography. Methanol, 50% aqueous methanol and 70% aqueous acetone extracts of different parts of four medicinal plants, Ficus benghalensis, Elaeocarpus sphaericus, Ipomea carnea and Azeratum conyzoides were prepared and screened for total phenolic and flavonoid contents and free radical scavenging activity. The total phenolics contents were measured spectrophotometrically by using Folin-Ciocalteu reagent and total flavonoids content by using aluminum chlor

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Benjamin, Amadi, Emelieze Mary, Ogunka-Nnoka Charity, Agomuo Nnabugwu, and Amadi Peter. "Proximate, GC-FID, and micronutrient analysis of ex-tracts of azadirachta indica." International Journal of Advanced Chemistry 5, no. 2 (2017): 73. http://dx.doi.org/10.14419/ijac.v5i2.8124.

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Different extraction media applied on the pulverized leaves of Neem plant (Azadirachta indica) were analyzed for its proximate, phytochemical, and micronutrient compositions, predominantly using the gas chromatographic technique. The results showed that the ethanol extract contained the highest amounts of carbohydrates and fibre. No significant difference (p>0.05) was recorded for the protein and ash content of both ethanol and methanol extracts, while the moisture and fat contents occurred highest in aqueous and methanol extracts respectively. The phytochemical screening revealed the absen

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Alawode, T. T., L. Lajide, B. J. Owolabi, and M. T. Olaleye. "Investigation of Bulb Extracts of Crinum jagus for Antibacterial and Antifungal Activities." Journal of Applied Sciences and Environmental Management 25, no. 1 (2021): 113–17. http://dx.doi.org/10.4314/jasem.v25i1.16.

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This study investigates the bulb extracts of Crinum jagus for antimicrobial activities. The bulb samples were dried, ground and subjected to successive extraction using hexane, ethylacetate and methanol. The extracts were screened for activity against Staphylococcus aureus, Escherichia coli, Bacillus subtilis, Pseudomonas aeruginosa, Salmonella typhi, Klebisidlae pneumonae, Candida albicans, Aspergillus niger, Penicillium notatum and Rhizopus stolonifer at concentrations between 6.25 and 200 mg/ml. Antimicrobial assays werecarried out using agar diffusion method. The Minimum Inhibitory Concent

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Musa, Maikudi Idris, Mamman Adamu, and Muhammad Aminu. "In vitro Screening of Potential Antioxidative and Toxicity of the Stembark Extracts from Sterculia setigera Del." Algerian Journal of Natural Products 8, no. 2 (2020): 774–79. https://doi.org/10.5281/zenodo.3973337.

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The current investigation deals with the <em>in vitro </em>antioxidative and toxicity effects of methanol and chloroform extracts from the stem bark of <em>Sterculia setigera</em>. The stem bark of the plant was extracted using organic solvents (methanol and chloroform) to afford methanol extract (ME) and chloroform extract (CE). The extracts were evaluated for antioxidative potentials using 2.2-diphenyl-1-picrylhydraxyl (DPPH) radical, also toxicity effect of the methanol extract was investigated against <em>Artemia salina larvae</em>. The antioxidative effects for the extracts uncovered prom

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Sozer Karadagli, Sumru, Borte Agrap, and Ferzan Lermioglu Erciyas. "Comparative HPLC Analysis and Antioxidant Properties of Different Solvent Extracts From Cinnamomum Cassia Bark." Acta Poloniae Pharmaceutica - Drug Research 81, no. 5 (2025): 739–48. https://doi.org/10.32383/appdr/197379.

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Cinnamomum cassia (L.) Presl. (C.Cassia) bark contains high amounts of antioxidant phenolic compounds and flavonoids Data on various biological properties of different extracts still appear to be insufficient in the literature. In this study, we prepared three extracts from C. cassia bark using hexane, chloroform, and methanol as solvents with different polarities. The study aimed to obtain a comparative analysis of the main components and antioxidant properties of these extracts. For the evaluation of antioxidant properties, total phenolic/flavonoid contents, and DPPH radical scavenging activ

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Sijabat, Yosi Yananda, Wilis Ari Setyati, and Retno Hartati. "Phytochemical Screening and Toxicity Test of Various Extracts from Microalgae <I>Dunaliella salina</I>." Jurnal Ilmiah Perikanan dan Kelautan 15, no. 1 (2023): 179–88. http://dx.doi.org/10.20473/jipk.v15i1.36282.

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Highlight Research Extract N-hexane of salina contains alkaloids, steroids, triterpenoids, and phenols Extract Ethyl Acetate of salina contains alkaloids, steroids, triterpenoids, phenols, flavonoid, and saponins Extract Methanol of salina contains alkaloids, steroids, triterpenoids, phenols, flavonoid, and saponins 24- hours LC50 value of the n-hexane extract salina was 276 ppm, the ethyl acetate extract was 673 ppm and the methanol extract was 811 ppm. All of the three extracts were included in toxic category Abstract Microalgae are single celled microorganisms as the primary producers in th

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Rizki, Muhammad Ikhwan, Liling Triyasmono, Khoerul Anwar, and Anna Khumaira Sari. "AKTIVITAS ANTIOKSIDAN EKSTRAK ETANOL, METANOL, DAN AQUADES DARI KULIT BUAH MUNDAR (Garcinia forbesii)." Jurnal Ilmiah Ibnu Sina (JIIS): Ilmu Farmasi dan Kesehatan 7, no. 2 (2022): 270–79. http://dx.doi.org/10.36387/jiis.v7i2.882.

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Mundar (Garcinia forbesii) is a typical plant from South Kalimantan. Mundar pericaps can be used as a natural antioxidant. The use of solvents in the extraction process can affect the antioxidant activity. The purpose of this study was to determine of phytochemical compounds and antioxidant activity of the ethanol, methanol, and aquades extracts from pericaps of mundar (Garcinia forbesii). Mundar pericaps is dried, then made into powder. Mundar pericaps powder was extracted with three different solvents, ethanol 70%, methanol, and aquades. Phytochemical screening and analysis by thin layer chr

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Chang, Chia Lin, and Che San Lin. "Phytochemical Composition, Antioxidant Activity, and Neuroprotective Effect ofTerminalia chebulaRetzius Extracts." Evidence-Based Complementary and Alternative Medicine 2012 (2012): 1–7. http://dx.doi.org/10.1155/2012/125247.

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The objectives of this study were to determine phytochemical compositions, chemiluminescence antioxidant activities, and neuroprotective effects on PC12 cells for water, methanol, and 95% ethanol extracts of the air-dried fruit ofTerminalia chebulaRetzius. The water extract afforded the greatest yield, and total phenolic and tannin content. The methanol extract yielded the greatest total triterpenoid content. Based on four chemiluminescence antioxidant assays, the three extracts showed various degrees of antioxidant activity. The methanol extract showed good antioxidant activity based on the h

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Darshitha, S. R., Lakshmeesha R., Chaithrashree, B. N., et al. "Phytochemical Analysis of Different Plant Extracts and their Inhibitory Effects on Aspergillus niger and Fusarium solani." Microbiology Research Journal International 34, no. 2 (2024): 23–31. http://dx.doi.org/10.9734/mrji/2024/v34i21429.

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Plant extracts constitutes versatile phytochemicals which can be substituted with commercial synthetic chemicals to inhibit the growth of pathogens. In this study, the methanol and aqueous extracts of guava, jackfruit, tulsi, peppermint and eucalyptus leaves were evaluated in-vitro against Aspergillus niger and Fusarium solani isolated from Pomegranate and Guava respectively. Plant extracts were prepared using Soxhlet apparatus and condensed the extract by rotary evaporation. Highest yield was obtained in methanol plant extracts compared to aqueous extract, as it causes differences in the pola

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Geetha, Sethupandian, Kokkaiah Irulandi, and Palanichamy Mehalingam. "EVALUATION OF ANTIOXIDANT AND FREE RADICAL SCAVENGING ACTIVITIES OF DIFFERENT SOLVENT EXTRACTS OF LEAVES OF PIPER UMBELLATUM." Asian Journal of Pharmaceutical and Clinical Research 10, no. 2 (2017): 274. http://dx.doi.org/10.22159/ajpcr.2017.v10i2.15570.

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Objective: This study was designed to determine the Total phenol, flavonoid content, antioxidant and free radical scavenging properties of different solvent extracts of Piper umbellatum. Methods: Different solvent extracts evaluated with DPPH radical scavenging activity and Reducing power activity.Results: The presence of phenol and flavonoid showed highly in the methanol extracts than ethyl acetate and acetone extracts. All the extracts have various level of antioxidant activity. Methanol solvent extract have good extraction and show significant antioxidant activity. The effect of reducing po

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