Relevant bibliographies by topics / Method for DNA methylation

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  1. Journal articles
  2. Dissertations / Theses
  3. Books
  4. Book chapters
  5. Conference papers
  6. Reports

Academic literature on the topic 'Method for DNA methylation'

Author: Grafiati
Published: 11 March 2023
Last updated: 19 July 2025

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Journal articles on the topic "Method for DNA methylation"

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Dang, Pengtao, Xiao Wang, Haiqi Zhu, et al. "Abstract 5352: Targeting DNA methylation in T cells to improve the efficacy of immunotherapy." Cancer Research 83, no. 7_Supplement (2023): 5352. http://dx.doi.org/10.1158/1538-7445.am2023-5352.

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Abstract T-cells are critical mediators of immunity and immunologic memory. Their cell fates are regulated in part through epigenetic mechanisms, including DNA methylation. Recent genome-wide methylation analyses have revealed dynamic alterations in the methylome at various stages of development and differentiation of T cells. At single cell level, it is not easy to simultaneously collect RNA-seq and RBBS methylation profiling. An important task is to understand the expression change of which genes and pathways are regulated by DNA methylations, especially for the ones that are associated with
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Majchrzak-Celińska, A., M. Naskret-Barciszewska, M. Giel-Pietraszuk, W. Nowak, P. Śron, and A. Barciszewska. "P02.08.A The relations of focal and total DNA methylation in gliomas." Neuro-Oncology 24, Supplement_2 (2022): ii31. http://dx.doi.org/10.1093/neuonc/noac174.101.

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Abstract Background The role of epigenetic events in gliomagenesis is undoubtful. However, the role of specific pathological events is not so clear. It was shown that loss in total DNA methylation correlates with higher tumor malignancy and oxidative DNA damage. But promoter methylation of many genes was reported to be significant for gliomas’ malignancy and predictive for the treatment outcome. In carcinogenesis in general global DNA hypomethylation and focal hypermethylation coexist. The aim of our project was to evaluate the correlation between total DNA methylation and promoter methylation
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Kim, Sook Ho, Hae Jun Jung, and Seok-Cheol Hong. "Z-DNA as a Tool for Nuclease-Free DNA Methyltransferase Assay." International Journal of Molecular Sciences 22, no. 21 (2021): 11990. http://dx.doi.org/10.3390/ijms222111990.

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Methylcytosines in mammalian genomes are the main epigenetic molecular codes that switch off the repertoire of genes in cell-type and cell-stage dependent manners. DNA methyltransferases (DMT) are dedicated to managing the status of cytosine methylation. DNA methylation is not only critical in normal development, but it is also implicated in cancers, degeneration, and senescence. Thus, the chemicals to control DMT have been suggested as anticancer drugs by reprogramming the gene expression profile in malignant cells. Here, we report a new optical technique to characterize the activity of DMT a
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Li, W., A. Van Soom, and L. Peelman. "Repeats as global DNA methylation marker in bovine preimplantation embryos." Czech Journal of Animal Science 62, No. 2 (2017): 43–50. http://dx.doi.org/10.17221/29/2016-cjas.

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DNA methylation undergoes dynamic changes and is a crucial part of the epigenetic regulation during mammalian early development. To determine the DNA methylation levels in bovine embryos, we applied a bisulfite sequencing based method aimed at repetitive sequences including three retrotransposons (L1_BT, BovB, and ERV1-1-I_BT) and Satellite I. A more accurate estimate of the global DNA methylation level compared to previous methods using only one repeat sequence, like Alu, could be made by calculation of the weighted arithmetic mean of multiple repetitive sequences, considering the copy number
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Kurdyukov, Sergey, and Martyn Bullock. "DNA Methylation Analysis: Choosing the Right Method." Biology 5, no. 1 (2016): 3. http://dx.doi.org/10.3390/biology5010003.

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IMAMURA, TAKUYA. "DNA methylation analysis with bisulfite sequencing method." Newsletter of Japan Society for Comparative Endocrinology, no. 113 (2004): 25–29. http://dx.doi.org/10.5983/nl2001jsce.2004.113_25.

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Hou, Peng, Meiju Ji, Song Li, Nongyue He, and Zuhong Lu. "High-throughput method for detecting DNA methylation." Journal of Biochemical and Biophysical Methods 60, no. 2 (2004): 139–50. http://dx.doi.org/10.1016/j.jbbm.2004.05.001.

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Choi, Woo Lee, Young Geun Mok, and Jin Hoe Huh. "Application of 5-Methylcytosine DNA Glycosylase to the Quantitative Analysis of DNA Methylation." International Journal of Molecular Sciences 22, no. 3 (2021): 1072. http://dx.doi.org/10.3390/ijms22031072.

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In higher eukaryotes DNA methylation is a prominent epigenetic mark important for chromatin structure and gene expression. Thus, profiling DNA methylation is important for predicting gene expressions associated with specific traits or diseases. DNA methylation is achieved by DNA methyltransferases and can be actively removed by specific enzymes in a replication-independent manner. DEMETER (DME) is a bifunctional 5-methylcytosine (5mC) DNA glycosylase responsible for active DNA demethylation that excises 5mC from DNA and cleaves a sugar-phosphate bond generating a single strand break (SSB). In
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Ridha, Inam, Chenxi Xu, Yining Zhang, et al. "Multiplexed Methylated DNA Immunoprecipitation Sequencing (Mx-MeDIP-Seq) to Study DNA Methylation Using Low Amounts of DNA." DNA 4, no. 4 (2024): 397–416. http://dx.doi.org/10.3390/dna4040028.

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Background/Objectives: DNA methylation is a key epigenetic mark involved in regulating gene expression. Aberrant DNA methylation contributes to various human diseases, including cancer, autoimmune disorders, atherosclerosis, and cardiovascular diseases. While whole-genome bisulfite sequencing and methylated DNA immunoprecipitation (MeDIP) are standard techniques for studying DNA methylation, they are typically limited to a few samples per run, making them expensive and low-throughput. Therefore, an automation-friendly method is needed to increase throughput and reduce costs without compromisin
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Khodadadi, Ehsan, Leila Fahmideh, Ehsaneh Khodadadi, et al. "Current Advances in DNA Methylation Analysis Methods." BioMed Research International 2021 (March 20, 2021): 1–9. http://dx.doi.org/10.1155/2021/8827516.

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DNA methylation is one of the epigenetic changes, which plays a major role in regulating gene expression and, thus, many biological processes and diseases. There are several methods for determining the methylation of DNA samples. However, selecting the most appropriate method for answering biological questions appears to be a challenging task. The primary methods in DNA methylation focused on identifying the state of methylation of the examined genes and determining the total amount of 5-methyl cytosine. The study of DNA methylation at a large scale of genomic levels became possible following
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Dissertations / Theses on the topic "Method for DNA methylation"

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Meng, Wei. "DNA Mutation/Methylation Screening Method for Colon Cancer Screening." Cleveland State University / OhioLINK, 2010. http://rave.ohiolink.edu/etdc/view?acc_num=csu1290364705.

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Trimarchi, Michael Paul Trimarchi. "Identification of endometrial cancer methylation features using a combined methylation analysis method." The Ohio State University, 2016. http://rave.ohiolink.edu/etdc/view?acc_num=osu1461302615.

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ZERILLI, FRANCESCO. "Development of an isothermal method for the detection of DNA hypermethylation." Doctoral thesis, Università degli Studi di Milano-Bicocca, 2009. http://hdl.handle.net/10281/7481.

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This thesis relates to the development of an isothermal method for the detection of DNA hypermethylation. The function of DNA methylation is to silence specific areas of the human genome and its maintenance is necessary to regulate key functions of the cell and of the organism. Aberrant hypermethylation of the promoter regions of several tumor suppressor genes can lead to formation of tumors and its detection, even at very early stages, can be an useful and powerful instrument for the diagnosis of the cancer, the determination of the prognosis and also to gauge the therapy. In this work we dev
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Hu, Ke. "METHODS AND ANALYSES IN THE STUDY OF HUMAN DNA METHYLATION." Case Western Reserve University School of Graduate Studies / OhioLINK, 2018. http://rave.ohiolink.edu/etdc/view?acc_num=case1522760441838452.

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Van, Heerden Chrisna. "Establishing a method for measuring the DNA methylation status of specific human genes / Chrisna van Heerden." Thesis, North-West University, 2006. http://hdl.handle.net/10394/1443.

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Antunes, Joana AP. "The Study of Tissue-Specific DNA Methylation as a Method for the Epigenetic Discrimination of Forensic Samples." FIU Digital Commons, 2017. https://digitalcommons.fiu.edu/etd/3676.

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In forensic sciences, the serological methods used to determine which body fluid was collected from the crime scene are merely presumptive or labor intensive since they rely on protein detection or on microscopic identification of cells. Given that certain forensic cases may need the precise identification of a body fluid to determine criminal contact, such is the example of a suspected sexual assault of a minor; certainty in the body fluid of origin may depict a precise picture of the events. The identification of loci that show differences in methylation according to the tissue of origin can
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Capparuccini, Maria. "Inferential Methods for High-Throughput Methylation Data." VCU Scholars Compass, 2010. http://scholarscompass.vcu.edu/etd/156.

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The role of abnormal DNA methylation in the progression of disease is a growing area of research that relies upon the establishment of sound statistical methods. The common method for declaring there is differential methylation between two groups at a given CpG site, as summarized by the difference between proportions methylated db=b1-b2, has been through use of a Filtered Two Sample t-test, using the recommended filter of 0.17 (Bibikova et al., 2006b). In this dissertation, we performed a re-analysis of the data used in recommending the threshold by fitting a mixed-effects ANOVA model. It was
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Kretzmer, Helene. "Methods for DNA Methylation Sequencing Analysis and their Application on Cancer Data." Doctoral thesis, Universitätsbibliothek Leipzig, 2016. http://nbn-resolving.de/urn:nbn:de:bsz:15-qucosa-203416.

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The fundamental subject of this thesis is the development of tools for the analysis of DNA methylation data as well as their application on bisulfite sequencing data comprising a large number of samples. DNA methylation is one of the major epigenetic modifications. It affects the cytosines of the DNA and is essential for the normal development of cells and tissues. Unusual alterations are associated with a variety of diseases and, specially, in cancergeneous tissues global changes in the DNA methylation level have been detected. To sequence DNA methylation on single nucleotide resolution, the
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Han, Chenggong. "Statistical models and computational methods for studying DNA differential methylation and 3D genome structure." The Ohio State University, 2020. http://rave.ohiolink.edu/etdc/view?acc_num=osu1595417277891892.

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Jackel, Jamie Nicole. "GEMINIVIRUSES AS MODELS TO STUDY THE ESTABLISHMENT AND MAINTENANCE OF DNA METHYLATION." The Ohio State University, 2013. http://rave.ohiolink.edu/etdc/view?acc_num=osu1367494030.

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Books on the topic "Method for DNA methylation"

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Jörg, Tost, ed. DNA methylation: Methods and protocols. 2nd ed. Humana Press, 2009.

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Jörg, Tost, ed. DNA methylation: Methods and protocols. 2nd ed. Humana Press, 2009.

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Kenkyūjo, Kokuritsu Kankyō. Gurōbaru na DNA mechiru-ka henka ni chakumokushita kankyō kagaku busshitsu no epijenetikusu sayō sukurīningu-hō no kaihatsu: Kankyōshō kankyō kenkyū gijutsu kaihatsu suishinhi shūryō kenkyū seika hōkokusho : Heisei 20-nendo--Heisei 21-nendo = Studies on the method for detecting epigenetics effects of environmental chemicals focusing on global changes of DNA methylation. Kankyōshō Sōgō Kankyō Seisakukyoku Kankyō Hokenbu Kankyō Anzenka Kankyō Risuku Hyōkashitsu, 2010.

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Wang, Sun-Chong. DNA methylation microarrays: Experimental design and statistical analysis. Edited by Petronis Art. Taylor & Francis, 2008.

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Erturk, Ece. Photochemical and Enzymatic Method for DNA Methylation Profiling and Walking Approach for Increasing Read Length of DNA Sequencing by Synthesis. [publisher not identified], 2018.

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Jost, Jean-Pierre, and Hans-Peter Saluz, eds. DNA Methylation. Birkhäuser Basel, 1993. http://dx.doi.org/10.1007/978-3-0348-9118-9.

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Tost, Jörg, ed. DNA Methylation. Humana Press, 2009. http://dx.doi.org/10.1007/978-1-59745-522-0.

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V, Beck Stephen, and Olek A, eds. The epigenome: Molecular hide and seek. Wiley-VCH, 2003.

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Mills, Ken I., and Bernie H. Ramsahoye. DNA Methylation Protocols. Humana Press, 2002. http://dx.doi.org/10.1385/1592591825.

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Tost, Jörg, ed. DNA Methylation Protocols. Springer New York, 2018. http://dx.doi.org/10.1007/978-1-4939-7481-8.

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Book chapters on the topic "Method for DNA methylation"

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El-Maarri, Osman. "Methods: DNA Methylation." In Advances in Experimental Medicine and Biology. Springer US, 2003. http://dx.doi.org/10.1007/978-1-4419-9072-3_23.

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Feng, Lingfang, and Jianlin Lou. "DNA Methylation Analysis." In Methods in Molecular Biology. Springer New York, 2018. http://dx.doi.org/10.1007/978-1-4939-8916-4_12.

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Akbari, Vahid, and Steven J. M. Jones. "Phasing DNA Methylation." In Methods in Molecular Biology. Springer US, 2022. http://dx.doi.org/10.1007/978-1-0716-2819-5_14.

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Hattori, Naoko, Yu-Yu Liu, and Toshikazu Ushijima. "DNA Methylation Analysis." In Methods in Molecular Biology. Springer US, 2023. http://dx.doi.org/10.1007/978-1-0716-3331-1_13.

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Dabe, Emily C., Andrea B. Kohn, and Leonid L. Moroz. "DNA Methylation in Ctenophores." In Methods in Molecular Biology. Springer US, 2024. http://dx.doi.org/10.1007/978-1-0716-3642-8_18.

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Rauch, Tibor A., and Gerd P. Pfeifer. "The MIRA Method for DNA Methylation Analysis." In Methods in Molecular Biology. Humana Press, 2009. http://dx.doi.org/10.1007/978-1-59745-522-0_6.

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Lin, Shili, Denise Scholtens, and Sujay Datta. "Sequencing-Based DNA Methylation Data." In Bioinformatics Methods. Chapman and Hall/CRC, 2022. http://dx.doi.org/10.1201/9781315153728-6.

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Cheishvili, David, Sophie Petropoulos, Steffan Christiansen, and Moshe Szyf. "Targeted DNA Methylation Analysis Methods." In Methods in Pharmacology and Toxicology. Springer New York, 2016. http://dx.doi.org/10.1007/978-1-4939-6743-8_3.

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Tiedemann, Rochelle L., Hope E. Eden, Zhijun Huang, Keith D. Robertson, and Scott B. Rothbart. "Distinguishing Active Versus Passive Using Illumina MethylationEPIC BeadChip Microarrays." In Methods in Molecular Biology. Springer US, 2021. http://dx.doi.org/10.1007/978-1-0716-1294-1_7.

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AbstractThe 5-carbon positions on cytosine nucleotides preceding guanines in genomic DNA (CpG) are common targets for DNA methylation (5mC). DNA methylation removal can occur through both active and passive mechanisms. Ten-eleven translocation enzymes (TETs) oxidize 5mC in a stepwise manner to 5-hydroxymethylcytosine (5hmC), 5-formylcytosine (5fC), and 5-carboxylcytosine (5caC). 5mC can also be removed passively through sequential cell divisions in the absence of DNA methylation maintenance. In this chapter, we describe approaches that couple TET-assisted bisulfite (TAB) and oxidative bisulfite (OxBS) conversion to the Illumina MethylationEPIC BeadChIP (EPIC array) and show how these technologies can be used to distinguish active versus passive DNA demethylation. We also describe integrative bioinformatics pipelines to facilitate this analysis.
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Sant, Karilyn E., Muna S. Nahar, and Dana C. Dolinoy. "DNA Methylation Screening and Analysis." In Methods in Molecular Biology. Humana Press, 2012. http://dx.doi.org/10.1007/978-1-61779-867-2_24.

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Conference papers on the topic "Method for DNA methylation"

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Bakr Kamel, Asmaa Abo, Nahla A. Belal, and Yasser El-Sonbaty. "A Novel Computational Method for Predicting DNA Methylation Sites within WGBS of Chromosome Y with WGS Data and Illumina Array Data." In 2023 33rd International Conference on Computer Theory and Applications (ICCTA). IEEE, 2023. https://doi.org/10.1109/iccta60978.2023.10969268.

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Son, Joo-Hiuk. "Active Demethylation of Cancer Cells using Terahertz Radiation for Potential Cancer Treatment." In Conference on Lasers and Electro-Optics/Pacific Rim. Optica Publishing Group, 2022. http://dx.doi.org/10.1364/cleopr.2022.cmp3a_02.

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Carcinogenesis involves DNA methylation which is a primary alteration in DNA in the development of cancer before genetic mutation. Because the abnormal DNA methylation is found in most cancer cells, the assessment of DNA methylation using terahertz radiation can be a novel optical method to detect and control cancer. The methylation has been directly observed by terahertz time-domain spectroscopy and this epigenetic chemical change could be manipulated to the state of demethylation using resonant terahertz radiation. Demethylation of cancer cells is a key issue in epigenetic cancer therapy and
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Sun, Xifang, Jiaqiang Zhu, and Shiquan Sun. "A Nonparametric Method for Detecting Differential DNA Methylation Regions." In 2020 IEEE International Conference on Bioinformatics and Biomedicine (BIBM). IEEE, 2020. http://dx.doi.org/10.1109/bibm49941.2020.9312983.

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Shiddiky, Muhammad J. A., Abu Ali Ibn Sina, Laura G. Carrascosa, Ramkumar Palanisamy, Sakandar Rauf, and Matt Trau. "Methylsorb: A simple method for quantifying DNA methylation using DNA-gold affinity interactions." In 2014 8th International Conference on Electrical and Computer Engineering (ICECE). IEEE, 2014. http://dx.doi.org/10.1109/icece.2014.7027002.

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Zheng, Kai, Hanzhe Liu, Simin Zhu, Huamei Li, and Xiaozhou Chen. "DNA Methylation Analysis Methods for Cancer Research." In 5th International Conference on Information Engineering for Mechanics and Materials. Atlantis Press, 2015. http://dx.doi.org/10.2991/icimm-15.2015.188.

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Kalofonou, Melpomeni, and Chris Toumazou. "An ISFET based analogue ratiometric method for DNA methylation detection." In 2014 IEEE International Symposium on Circuits and Systems (ISCAS). IEEE, 2014. http://dx.doi.org/10.1109/iscas.2014.6865514.

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Yudianto, Ahmad, Masniari Novita, Muhammad Afiful Jauhani, and Deka Bagus Binarsa. "DNA Methylation on Bloodstain as a Forensic Age Estimation Method." In International Conference on Law, Economics and Health (ICLEH 2020). Atlantis Press, 2020. http://dx.doi.org/10.2991/aebmr.k.200513.006.

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Carvalho, GFS, LL Vieira, BM Wolff, et al. "EPIGENOMIC ANALYSIS REVEAL CRITICAL ASSOCIATION BETWEEN METHYLATION STATUS AND CLINICAL PHENOTYPE." In Resumos do 54º Congresso Brasileiro de Patologia Clínica/Medicina Laboratorial. Zeppelini Editorial e Comunicação, 2022. http://dx.doi.org/10.5327/1516-3180.140s1.5803.

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Objective: Copy number variations (CNVs) are DNA fragments deleted or duplicated in relation to a reference genome. Some genome variants, classified as variants with uncertain significance (VUS), do not present a safe conclusion with clinical phenotypes, which makes the diagnostic conclusion difficult. We know that hypermethylation of gene promoter regions often leads to transcriptional silencing, in addition to DNA methylation changes in gene and/or intergenic regions can play a critical role in genomic regulation and stability. With epigenomic investigation, we can gain a more comprehensive
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Almeida, V., SN Chehimi, GFS Carvalho, et al. "DIFFERENCE IN METHYLATION STATUS OF REMAINING ALLELE IN SIBLINGS WITH THE SAME DELETION SIZE IN 5P." In Resumos do 54º Congresso Brasileiro de Patologia Clínica/Medicina Laboratorial. Zeppelini Editorial e Comunicação, 2022. http://dx.doi.org/10.5327/1516-3180.140s1.6429.

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Objective: Cri Du Chat syndrome or 5psyndrome (OMIM #123450) is characterized by a genomic loss in the short arm of chromosome 5 and by variable clinical manifestations, that include high-pitched cry in newborns. The phenotypic variability in this syndrome may not be limited only to variations in gene structure – such as deletions, duplications, inversions, insertions and translocations – as DNA methylation mechanisms, which occurs mainly in the “CpG Islands”, are also possible. Therefore, we studied the methylation status of the remaining allele of region of breakpoint at 5pin siblings, an 11
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Kulikowski, LD, G. Carvalho, YG Oliveira, et al. "METHYLATION AND BIOLOGICAL AGE ANALYSIS IN ADHD PATIENTS." In Resumos do 54º Congresso Brasileiro de Patologia Clínica/Medicina Laboratorial. Zeppelini Editorial e Comunicação, 2022. http://dx.doi.org/10.5327/1516-3180.140s1.5854.

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Objective: Attention deficit/hyperactivity disorder (ADHD) is a common behavioral syndrome that begins in childhood and affects 3.4% of children worldwide. Due to its etiological complexity, there are no consistent biomarkers for ADHD, however the high heritability that the disorder presents indicates an influence of genetic/ epigenetic factors. The main epigenetic mechanisms is DNA methylation, a process with an important role in gene expression and in many biological pathways. Methylation status can be used as a biomarker for clinical conditions, such as cancer and neuropsychiatric diseases
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Reports on the topic "Method for DNA methylation"

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Cohen, Yuval, Christopher A. Cullis, and Uri Lavi. Molecular Analyses of Soma-clonal Variation in Date Palm and Banana for Early Identification and Control of Off-types Generation. United States Department of Agriculture, 2010. http://dx.doi.org/10.32747/2010.7592124.bard.

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Date palm (Phoenix dactylifera L.) is the major fruit tree grown in arid areas in the Middle East and North Africa. In the last century, dates were introduced to new regions including the USA. Date palms are traditionally propagated through offshoots. Expansion of modern date palm groves led to the development of Tissue Culture propagation methods that generate a large number of homogenous plants, have no seasonal effect on plant source and provide tools to fight the expansion of date pests and diseases. The disadvantage of this procedure is the occurrence of off-type trees which differ from t
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Muyle, Aline. Analysis of DNA Methylation. Instats Inc., 2024. http://dx.doi.org/10.61700/6ayq8hff26qxn1470.

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This three-day workshop provides comprehensive training in the analysis of DNA methylation, a key epigenetic modification influencing gene expression and controlling the spread of transposable elements in genomes. Led by Dr Aline Muyle, participants will gain theoretical knowledge and practical skills in data preprocessing, statistical analysis, and visualization using RStudio and various bioinformatic software using Bash scripts. The workshop is suited for researchers in Biostatistics, Biology, Genetics, Ecology, Evolution, Bioinformatics, Molecular Biology, and Medical Research.
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Head, Thomas J., and Susannah Gal. DNA Based Fluid Computing Using Methylation. Defense Technical Information Center, 2005. http://dx.doi.org/10.21236/ada436701.

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Yamamoto, Fumiichiro. DNA Methylation Alterations in Breast Cancer. Defense Technical Information Center, 2001. http://dx.doi.org/10.21236/ada405531.

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Yamamoto, Fumiichiro. DNA Methylation Alterations in Breast Cancer. Defense Technical Information Center, 2002. http://dx.doi.org/10.21236/ada408999.

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Cullen, Kevin J. The Effect of DNA Methylation on IGF2 Expression. Defense Technical Information Center, 1998. http://dx.doi.org/10.21236/ada361324.

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Huang, Tim H. M. Epigenetic Changes in DNA methylation in Breast Cancer. Defense Technical Information Center, 1999. http://dx.doi.org/10.21236/ada384184.

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ไชยวงศ์คต, อาคม, ภาวพันธ์ ภัทรโกศล та สมชัย นิรุตติศาสน์. การตรวจหาภาวะการเปลี่ยนแปลงการควบคุมเหนือพันธุกรรมในตัวอย่างเซลล์ปากมดลูกที่มีความผิดปกติระดับต่างๆ : รายงานการวิจัย. จุฬาลงกรณ์มหาวิทยาลัย, 2016. https://doi.org/10.58837/chula.res.2016.27.

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โรคมะเร็งปากมดลูกเป็นโรคมะเร็งที่พบมากเป็นอันดับสองในผู้หญิงทั่วโลก โดยเฉพาะในประเทศกำลังพัฒนา ซึ่งรวมประเทศไทยด้วย มีการศึกษาพบภาวะ global DNA hypomethylation ในเซลล์มะเร็งชนิดต่างๆ รวมถึงมะเร็งปากมดลูกด้วย การศึกษานี้จึงสนใจพัฒนาวิธี Enzyme linked immunosorbent assay (ELISA) ในการตรวจ global DNA methylation เพื่อตรวจกรองมะเร็งปากมดลูกซึ่งวิธี ELISA เหมาะสมกับประเทศกำลังพัฒนา วิธีดำเนินการวิจัย การศึกษานี้พัฒนาวิธี ELISA ในการตรวจ global DNA methylation พร้อมเปรียบเทียบผลกับวิธี bisulfite LINE1 pyrosequencing โดยใช้ตัวอย่างดีเอ็นเอที่สกัดจากเซลล์ปากมดลูกที่มีความผิดปกติระดับต่างๆ ผลการวิจัย โ
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9

Singal, Rakesh. Aberrant Promoter Methylation in Serium DNA as a Biomarker for Prostate Cancer. Defense Technical Information Center, 2005. http://dx.doi.org/10.21236/ada452528.

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10

Rusiecki, Jennifer A., Louis French, Zygmunt Galdzicki, et al. Epigenetic Patterns of TBI: DNA Methylation in Serum of OIF/OEF Servicemembers. Defense Technical Information Center, 2012. http://dx.doi.org/10.21236/ada585498.

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