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Journal articles on the topic 'Method of cells (MOC)'

Author: Grafiati

Published: 5 June 2025

Last updated: 15 July 2025

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1

Li, Jin, Yunlin Xu, Dean Wang, Qicang Shen, Brendan Kochunas, and Thomas Downar. "DEMONSTRATION OF A LINEAR PROLONGATION CMFD METHOD ON MOC." EPJ Web of Conferences 247 (2021): 03006. http://dx.doi.org/10.1051/epjconf/202124703006.

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Coarse Mesh Finite Difference (CMFD) method is a very effective method to accelerate the iterations for neutron transport calculation. But it can degrade and even fail when the optical thickness of the mesh becomes large. Therefore several methods, including partial current-based CMFD (pCMFD) and optimally diffusive CMFD (odCMFD), have been proposed to stabilize the conventional CMFD method. Recently, a category of “higherorder” prolongation CMFD (hpCMFD) methods was proposed to use both the local and neighboring coarse mesh fluxes to update the fine cell flux, which can solve the fine cell sc

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Ahmadi, Kaveh, and Russell T. Johns. "Multiple-Mixing-Cell Method for MMP Calculations." SPE Journal 16, no. 04 (2011): 733–42. http://dx.doi.org/10.2118/116823-pa.

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Summary The minimum miscibility pressure (MMP) is a key parameter governing the displacement efficiency of gasfloods. There are several methods to determine the MMP, but the most accurate methods are slim-tube experiments, analytical methods, and numerical-simulation/cell-to-cell methods. Slim-tube experiments are important to perform because they use actual crude oil, but they are costly and time consuming. Analytical methods that use the method of characteristics (MOC) are very fast and help to understand the structure of gasfloods. MOC, however, relies on finding the unique and correct set

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Speirs, V., S. Eich-Bender, C. R. Youngson, and E. Cutz. "Localization of MOC-1 cell surface antigen in small-cell lung carcinoma cell lines: an immunohistochemical and immunoelectron microscopic study." Journal of Histochemistry & Cytochemistry 41, no. 9 (1993): 1303–10. http://dx.doi.org/10.1177/41.9.8394853.

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Expression of cell surface antigens of the neural cell adhesion molecule (N-CAM) class was recently shown to be shared by both fetal and neoplastic neuroendocrine cells, including those of the lung. We investigated the expression and localization of MOC-1 antigen on small-cell (neuroendocrine) lung carcinoma cell lines with immunohistochemical methods at the light (LM) and electron microscopy (EM) level and by Western blot. At LM level, using monoclonal antibody (MAb) MOC-1 with the ABC method and immunofluorescence, positive staining was observed on surfaces of cells from all tumor lines exam

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Busek, M., M. Nötzel, C. Polk, and F. Sonntag. "Characterization and simulation of peristaltic micropumps." Journal of Sensors and Sensor Systems 2, no. 2 (2013): 165–69. http://dx.doi.org/10.5194/jsss-2-165-2013.

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Abstract. The aim of the work is to find an analytical model of a pneumatic micropump which was integrated into a cell-culture system. This allows the estimation of peak velocities and wall-shear stress influencing the cultured cells in our multi-organ-chip (MOC) with respect to the applied pressure and the geometric properties of the pump. By adjusting those parameters, one can imitate physiological or pathological heart activity. The calculated flow within the MOC was compared to experimental results obtained via the non-invasive micro-PIV method.

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Yoon, S., R. Choi, S. Cho, et al. "OS10.6.A What is the initial cell in the subventricular zone for human glioblastoma genesis?" Neuro-Oncology 24, Supplement_2 (2022): ii22. http://dx.doi.org/10.1093/neuonc/noac174.069.

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Abstract Background We all have a fundamental question about why glioblastoma (GBM) develops. In order to find the answer to this fundamental question, if you find out what the first cell is, you will get closer to the answer. GBM arises from the subventricular zone (SVZ). GBM is one of the most devastating tumour of human brain as the most optimal treatment barely prolongs the survival, and it does not cure the disease. As the majority of GBM tissues show copy number variations (CNV) of co-altered chromosomal 7 gain and 10 loss, we hypothesized the origin cell (Oc) of SVZ may be traced back w

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van Rooijen, W. F. G., and G. Chiba. "Diffusion coefficients for LMFBR cells calculated with MOC and Monte Carlo methods." Annals of Nuclear Energy 38, no. 1 (2011): 133–44. http://dx.doi.org/10.1016/j.anucene.2010.08.004.

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Nguyen Thi, Phuong, Thu Le Van, Lang Ngo Van, Tue Nguyen Trong та Quan Duong Hong. "Đặc điểm một số chỉ số tế bào máu ngoại vi và Ferritin huyết thanh ở người bệnh Thalassemia sau điều trị thải sắt bằng Deferiprone tại Bệnh viện đa khoa Mộc Châu năm 2023". Journal of Health and Development Studies 08, № 02 (2024): 27–35. http://dx.doi.org/10.38148/jhds.0802skpt23-077.

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Objective: Evaluate changes in some peripheral blood cell indices and serum Ferritin in Thalassemia patients after iron chelation treatment with Deferiprone at Moc Chau general Hospital in 2023; Methods: Cross-sectional, retrospective study. 44 patients with Thalassemia treated at Moc Chau general Hospital in 2023; Results: The average age of disease was 11 ± 12.05 years old. The rate of carrying genes for β-Thalassemia and α-Thalassemia was 97.73% and 2.27%, respectively. The Thai ethnic group had the highest rate of disease (70.45%), followed by Muong (20.45%), Xinh mun (4.55) and Dao (4.55%

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Zhang, Kaiyi, Bahareh Nojabaei, Kaveh Ahmadi, and Russell T. Johns. "Effect of Gas/Oil Capillary Pressure on Minimum Miscibility Pressure for Tight Reservoirs." SPE Journal 25, no. 02 (2019): 820–31. http://dx.doi.org/10.2118/199354-pa.

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Summary Shale and tight reservoir rocks have pore throats on the order of nanometers, and, subsequently, a large capillary pressure. When the permeability is ultralow (k &lt; 200 nd), as in many shale reservoirs, diffusion might dominate over advection, so that the gas injection might no longer be controlled by the multicontact minimum miscibility pressure (MMP). For gasfloods in tight reservoirs, where k &gt; 200 nd and capillary pressure is still large, however, advection likely dominates over diffusive transport, so that the MMP once again becomes important. This paper focuses on th

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Sanchez-Petitto, Gabriela, Maria Calbacho, Agata Wieczorkiewicz-Kabut, et al. "MO-TRANS: A Randomized, Double-Blind, Placebo-Controlled, Multi-Center Phase III Study of Mocravimod (MOC) As Adjunctive and Maintenance Treatment in AML Patients Undergoing Allogeneic Hematopoietic Cell Transplantation." Blood 144, Supplement 1 (2024): 4952.1. https://doi.org/10.1182/blood-2024-203080.

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Introduction: In allogeneic hematopoietic cell transplantation (allo-HCT), relapse is one of the major causes of mortality, morbidity, and quality of life impairment. There is an unmet medical need for novel therapies to mitigate this risk. Mocravimod (MOC), a sphingosine-1-phosphate receptor (S1PR) modulator, down regulates the S1PR1 on T-cells and other lymphocytes. This ligand-induced internalization of the S1PR1 renders these cells unresponsive to S1P and deprives them of an obligatory signal to egress from lymphoid organs and thus has been demonstrated to have a dual effect: efficiently s

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10

Mardiana, Ummy, Christophe Innocent, Marc Cretin, and Buchari Buchari. "A New Method of Bio-Catalytic Surface Modification for Microbial Desalination Cell." International Journal of Renewable Energy Development 10, no. 2 (2021): 345–54. http://dx.doi.org/10.14710/ijred.2021.34235.

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A microbial desalination cell (MDC) built on a modified surface has been studied for seawater desalination. The goal of this study is to provide and develop a seawater desalination system that does not require energy support by applying a modification of the anode as an electron acceptor. The different potential charges that occur between anode and cathode can serve as the driving force for electrodialysis of seawater, resulting in its desalination. Yeast has been applied as a biocatalyst and neutral red has been chosen as a redox mediator to facilitate the electron transport originating from

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Kim, Young Cheol, Hong-Kyu Jang, Geunsu Joo, and Ji Hoon Kim. "A Comparative Study of Micromechanical Analysis Models for Determining the Effective Properties of Out-of-Autoclave Carbon Fiber–Epoxy Composites." Polymers 16, no. 8 (2024): 1094. http://dx.doi.org/10.3390/polym16081094.

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This study aims to critically assess different micromechanical analysis models applied to carbon-fiber-reinforced plastic (CFRP) composites, employing micromechanics-based homogenization to accurately predict their effective properties. The paper begins with the simplest Voigt and Reuss models and progresses to more sophisticated micromechanics-based models, including the Mori–Tanaka and Method of Cells (MOC) models. It provides a critical review of the areas in which these micromechanics-based models are effective and analyses of their limitations. The numerical analysis results were confirme

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Khelifa, Asma S., Katherine L. Lothstein, Masaya Miyamoto, et al. "Abstract 4082: Anchored IL-12 synergizes with an epigenetic modulator to promote immune remodeling and overcome anti-PD1-refractory murine tumors." Cancer Research 84, no. 6_Supplement (2024): 4082. http://dx.doi.org/10.1158/1538-7445.am2024-4082.

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Abstract Background Most patients with solid malignancies harbor innate or acquired resistance to immune checkpoint blockade (ICB), prompting the need for novel therapeutic strategies. Interleukin-12 (IL-12) is a promising cytokine for cancer therapy due to its ability to bridge innate and adaptive immunity. However, a narrow therapeutic index limits the use of systemic IL-12 therapy. Here, we investigated the tumor-suppressive effects and mode of action of intra-tumorally delivered murine Interleukin-12 anchored to aluminum hydroxide (referred as mANK-101) in combination with the class I HDAC

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Domingues, Joana, Manuela Goulão, Fernanda Delgado, José Carlos Gonçalves, Joana Gonçalves, and Cristina Santos Pintado. "Essential Oils of Two Portuguese Endemic Species of Lavandula as a Source of Antifungal and Antibacterial Agents." Processes 11, no. 4 (2023): 1165. http://dx.doi.org/10.3390/pr11041165.

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Chemical investigations of L. stoechas subsp. luisieri and L. pedunculata essential oils were analyzed by GC-MS, and the antimicrobial activity was performed against bacteria and fungi isolated from food sources. The cytotoxicity of the essential oil was performed in NHDF cells using the MTT method. According to the results, the main compounds of L. stoechas subsp. luisieri essential oil were trans-α-necrodyl acetate (40.2%), lavandulyl acetate (11%), and trans-α-necrodol (10.4%), while fenchone (50.5%) and camphor (30.0%) in L. pedunculata essential oil. The antifungal activity of essential o

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14

Brudnik, R., P. Toosi, T. A. Barklow, M. S. Shurbaji, and G. A. Youngberg. "Comparison of immunohistochemical (IHC) staining for BerEp4 and MOC31 in Bowen Disease (BD)." American Journal of Clinical Pathology 160, Supplement_1 (2023): S26. http://dx.doi.org/10.1093/ajcp/aqad150.058.

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Abstract Introduction/Objective Ber-EP4 and MOC31 are antibodies that target the epithelial cell adhesion molecule (Ep- CAM). In dermatopathology, BerEP4 IHC is classically used to differentiate between basal cell carcinoma (positive) and primary squamous cell carcinoma of the skin (negative). BerEP4 also stains pagetoid tumor cells in Paget Disease (PD), and can be used as part of a panel to assist in differentiating Paget Disease (positive) and Bowen Disease (presumed negative). However, a published abstract reported the unexpected finding that some cases of BD can stain variably positive fo

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15

Yang, Juan, Wenhao Liu, Haoyu Zhao, and Qingsong Zhang. "Experimental Investigation of Lithium-Ion Batteries Thermal Runaway Propagation Consequences under Different Triggering Modes." Aerospace 11, no. 6 (2024): 438. http://dx.doi.org/10.3390/aerospace11060438.

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In the stage of aircraft development and airworthiness verification, it is necessary to master the influence of lithium-ion battery (LIB) thermal runaway (TR) propagation. In this paper, the battery TR propagation behavior under different trigger positions and modes is studied experimentally, and the calculation and comparison are carried out from the parameters of real-time temperature, voltage, propagation speed, total energy released, and solid ejecta. When the two adjacent cells at the top corner, side, and center of the module are overheated, TR occurs at about 1000 s for the triggered ce

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16

Limsuwan, Surasak, Thanagrit Thammathirata, Chutha Takahashi Yupanquic, et al. "In vitro Antimicrobial and NO Inhibitory Activities of A Thai Herbal Recipe Against Cutibacterium acnes, Staphylococcus aureus and Staphylococcus epidermidis." Trends in Sciences 22, no. 6 (2025): 9989. https://doi.org/10.48048/tis.2025.9989.

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Introduction: Acanthus ebracteatus (AE), Curcuma longa (CL) (rhizome), (leaf and stem), and Quercus infectoria (QI) (gall) (ACQ03 recipe) have long been used to treat skin and inflammatory conditions. In addition, it has been used in traditional Thai medicine hospitals to treat acne. This study is aimed to evaluate the antibacterial and anti-inflammatory effects of ACQ03 recipe. Materials and methods: ACQ03 recipe was evaluated antibacterial using broth microdilution, a time-kill assay and nitric oxide inhibitory effects and cytotoxicity activities. The ingredients that make up the ethanol ext

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MONI, Esther Del Florence NDEDI, Maximilienne Ascension NYEGUE, Jean Paul ASSAM ASSAM, et al. "Effects Of Essential Oil From Drypetes gossweileri S. Moore Stem Barks On Cell Release And Dna Synthesis Of Mycobacterium tuberculosis." Journal of Drug Delivery and Therapeutics 9, no. 2-s (2019): 319–24. http://dx.doi.org/10.22270/jddt.v9i2-s.2644.

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Background: In the recent years, the proliferation of multi-drug-resistant and extensively drug-resistant strain to tuberculosis (TB) suggest that efforts are required to find alternative treatments. The designed study aimed to show the effects of essential oils (EO) from Drypetes gossweileri stem barks on Mycobacterium tuberculosis cell membrane release and DNA synthesis. Methods: The minimal inhibitory concentration (MIC) and minimal bactericidal concentration (MBC) were determined against two clinical isolates (IS53 and IS310) and the reference strain H37Rv ATCC 27294 using microdilution me

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Xu, Lingfei, and Huazhou Li. "A Modified Multiple-Mixing-Cell Method with Sub-Cells for MMP Determinations." Energies 14, no. 23 (2021): 7846. http://dx.doi.org/10.3390/en14237846.

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Minimum miscible pressure (MMP) is an essential design parameter of gas flooding for enhanced oil recovery (EOR) applications. Researchers have developed a number of methods for MMP computations, including the analytical methods, the slim-tube simulation method, and the multiple-mixing-cell (MMC) method. Among these methods, the MMC method is widely accepted for its simplicity, robustness, and moderate computational cost An important version of the MMC method is the Jaubert et al. method which has a much lower computational cost than the slim-tube simulation method. However, the original Jaube

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Rahul, Sharma, Kumar Gaba Vivek, I. Kundalwal S., and Suresh Kumar R. "Estimation of thermal properties of fuzzy carbon fiber heat exchanger using micromechanics approach." Journal of Indian Chemical Society Vol. 97, Jul 2020 (2020): 1169–77. https://doi.org/10.5281/zenodo.5674201.

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Department of Mechanical Engineering, National Institute of Technology Raipur, Raipur-492 010, Chhattisgarh, India Department of Mechanical Engineering, Indian Institute of Technology Indore, Indore-453 552, Madhya Pradesh, India <em>E-mail</em>: rskumar.me@nitrr.ac.in <em>Manuscript received online 28 March 2020, accepted 15 June 2020</em> Effect of straight radially grown carbon nanotubes (CNTs) on the periphery of a hollow cylindrical fiber (HCF) has been considered for the thermal conductivity estimation the proposed fiber. Such a hollow fiber with the presence of CNTs on the periphery is

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Khatami, Mehrdad, Mohammad Reza Aflatoonian, Hakim Azizi, et al. "Evaluation of Antibacterial Activity of Iron Oxide Nanoparticles Against Escherichia coli." International Journal of Basic Science in Medicine 2, no. 4 (2017): 166–69. http://dx.doi.org/10.15171/ijbsm.2017.31.

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Introduction: Considering the usefulness of metal oxide nanoparticles in biology and biomedicine, iron oxide nanoparticles were biosynthesized using bioresource engineering to evaluate its antibacterial activity against Escherichia coli. Methods: Macrodilution method was used for calculating the lowest concentration which prevented the growth of bacteria (minimum inhibitory concentration [MIC]), and the lowest concentration that destroyed all bacterial cells (minimum bactericidal concentration [MBC]). Results: The lowest concentration of iron oxide nanoparticles that inhibited the growth of E.

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Ade, Brian J., Nicholas P. Luciano, Andrew J. Conant, et al. "DEVELOPMENT OF MPACT FOR FULL-CORE SIMULATIONS OF MAGNOX GAS-COOLED NUCLEAR REACTORS." EPJ Web of Conferences 247 (2021): 06041. http://dx.doi.org/10.1051/epjconf/202124706041.

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The MPACT code, jointly developed by Oak Ridge National Laboratory and University of Michigan, is designed to perform high-fidelity light water reactor (LWR) analysis using wholecore pin-resolved neutron transport calculations on modern parallel-computing hardware. MPACT uses the subgroup method for resonance self-shielding, while the primary neutron transport solver uses a 2D/1D method that is based on the method of characteristics (MoC) for the x-y planes coupled with a 1D diffusion or transport solver in the axial dimension. Additional geometry capabilities are currently being developed in

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Fiordalisi, Samira de Aquino Leite, Luciana Aparecida Honorato, and Shirley Kuhnen. "Aloe barbadensis Miller leaf exudate is a potential treatment for bovine mastitis." F1000Research 7 (August 14, 2018): 1285. http://dx.doi.org/10.12688/f1000research.15671.1.

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Background: Aloe barbadensis Miller is a well-known phytotherapeutic, and parts of its leaves are used for a wide range of medicinal purposes. This study seeks to assess the in vitro antimicrobial and cytotoxic effects of leaf exudate (LE) from A. barbadensis leaves against Staphylococcus aureus and MAC-T bovine mammary epithelial cells. Methods: Seasonal LE samples were collected, and the effect on total phenolic and aloin contents was determined. Antimicrobial activity of LE was evaluated using the broth microdilution method, and toxicity to MAC-T cells was determined by MTT assay. Results:

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Fiordalisi, Samira de Aquino Leite, Luciana Aparecida Honorato, and Shirley Kuhnen. "Aloe barbadensis Miller leaf exudate is a potential treatment for bovine mastitis." F1000Research 7 (October 26, 2018): 1285. http://dx.doi.org/10.12688/f1000research.15671.2.

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Background: Aloe barbadensis Miller, also known as Aloe vera is a well-known phytotherapeutic, and parts of its leaves are used for a wide range of medicinal purposes. This study seeks to assess the in vitro antimicrobial and cytotoxic effects of leaf exudate (LE) from A. barbadensis leaves against Staphylococcus aureus and MAC-T bovine mammary epithelial cells. Methods: Seasonal LE samples were collected, and the effect on total phenolic and aloin contents was determined. Antimicrobial activity of LE was evaluated using the broth microdilution method, and toxicity to MAC-T cells was determine

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He, Nan, Juan Zhou, Miyun Hu, Changyang Ma, and Wenyi Kang. "The mechanism of antibacterial activity of corylifolinin against three clinical bacteria from Psoralen corylifolia L." Open Chemistry 16, no. 1 (2018): 882–89. http://dx.doi.org/10.1515/chem-2018-0091.

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AbstractEffective antibacterial activity against Grampositive bacteria isolated in clinical strains was exhibited when corylifolinin was tested using the Disc diffusion method (K-B method). Minimum inhibitory concentration (MIC) of corylifolinin against Staphylococcus aureus (SA), Methcillin-resistant Staphylococcus aureus (MRSA) and extended spectrum β-lactamases Staphylococcus aureus (ESBLs-SA) were 0.078, 0.156 and 0.078 mg/mL, respectively. The minimum bactericide concentrations (MBCs) were 0.156, 0.156 and 0.078 mg/mL respectively. Scanning electron microscopy (SEM), alkaline phosphatase

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Lees, Jason R., Saule Nurmukhambetova, Yong Chan Kim, et al. "Using transgenic MHC class II/self-peptide reactive cytotoxic T cells as a method of ameliorating established EAE." Journal of Immunology 198, no. 1_Supplement (2017): 127.27. http://dx.doi.org/10.4049/jimmunol.198.supp.127.27.

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Abstract In multiple sclerosis (MS) CD4+ T cells are thought to coordinate initiation and maintenance of neuroinflammation following recognition of central nervous system (CNS) antigens in the context of MHC class II molecules. Re-activation of these CNS antigen specific CD4+ T cells within the CNS is thought to be crucial to recruitment of secondary immune effector cells and resultant tissue inflammation. MHC class II is thought to be expressed on professional antigen presenting cells (APC) but not on oligodendrocytes and neurons, two cellular targets for MS pathology. Here we examine the use

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Yetendje Chimi, Larissa, Armel Joseph Agokeng, Guy Sedar Singor Njateng, and Jean Paul Dzoyem. "Effect of combination of doxycycline with natural products against planktonic cells, biofilm, and virulence factor of Pseudomonas aeruginosa." Investigational Medicinal Chemistry and Pharmacology 7, no. 1 (2023): 1–8. http://dx.doi.org/10.31183/imcp.2024.00091.

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Background: Pseudomonas aeruginosa is an important environmental, opportunistic, and nosocomial pathogen with a significant threat to public health. Combination therapy has many advantages due to the simultaneous action of two drugs on two separate cellular targets. In the present study, the effect of the combination of doxycycline and natural products against planktonic cells, biofilm, and virulence factors of P. aeruginosa was evaluated. Methods: To perform this work, minimal inhibitory concentration (MIC) and minimal bactericidal concentration (MBC) of doxycycline and natural products were

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Bates, Briana L., Joseph A. Mikulin, and Timothy J. Wilson. "A single-marker method of renal cDC2 isolation." Journal of Immunology 204, no. 1_Supplement (2020): 159.42. http://dx.doi.org/10.4049/jimmunol.204.supp.159.42.

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Abstract Because of their ability to present antigens, respond to inflammatory signals, and produce critical acute-phase cytokines, renal dendritic cells are of particular interest to those studying various disease states of the kidney. Markers such as CD11c, MHC-II, CX3CR1, and CD11b have historically been used in the murine system to isolate renal dendritic cells from the various parenchymal cells among which they’re embedded. In this study, we have determined that signaling lymphocyte activation molecule family member 9 (SLAMF9) is sufficient to mark the population of CD11b+ MHCIIhi CX3CR1+

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Ivanović, Milena, Dragana Grujić, Janez Cerar, et al. "Extraction of Bioactive Metabolites from Achillea millefolium L. with Choline Chloride Based Natural Deep Eutectic Solvents: A Study of the Antioxidant and Antimicrobial Activity." Antioxidants 11, no. 4 (2022): 724. http://dx.doi.org/10.3390/antiox11040724.

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In this study, the extraction efficiency of natural deep eutectic solvents (NADES) based on choline chloride as a hydrogen bond acceptor (HBA) and five different hydrogen bond donors (HBD; lactic acid, 1,4-butanediol, 1,2-propanediol, fructose and urea) was evaluated for the first time for the isolation of valuable bioactive compounds from Achillea millefolium L. The phytochemical profiles of NADES extracts obtained after ultrasound-assisted extraction were evaluated both spectrophotometrically (total phenolic content (TPC) and antioxidant assays) and chromatographically (UHPLC-MS and HPLC-UV)

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PANG, LIPING, LISHA WANG, TALIN SUO та ін. "Tumor Necrosis Factor-α Blockade Leads to Decreased Peripheral T Cell Reactivity and Increased Dendritic Cell Number in Peripheral Blood of Patients with Ankylosing Spondylitis". Journal of Rheumatology 35, № 11 (2008): 2220–28. http://dx.doi.org/10.3899/jrheum.080219.

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ObjectiveTo study the effect of tumor necrosis factor-α (TNF-α) antagonist (etanercept) treatment on the peripheral T cell reactivity of patients with ankylosing spondylitis (AS).MethodsPeripheral blood mononuclear cells were collected from 40 patients with AS at baseline, after 2 and 6 weeks of etanercept treatment or placebo treatment, and from healthy controls. The number of cells secreting various cytokines was detected by enzyme linked immunospot. Serum soluble interleukin 2 (IL-2) receptor level was measured by ELISA. T cell proliferation was assayed with the WST-1 live cell-staining met

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VORAVUTHIKUNCHAI, SUPAYANG PIYAWAN, SUHAILA DOLAH, and WILAWAN CHARERNJIRATRAKUL. "Control of Bacillus cereus in Foods by Rhodomyrtus tomentosa (Ait.) Hassk. Leaf Extract and Its Purified Compound." Journal of Food Protection 73, no. 10 (2010): 1907–12. http://dx.doi.org/10.4315/0362-028x-73.10.1907.

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Edible natural products, either standardized plant extracts or pure compounds, provide unlimited opportunities as safe new antimicrobial agents. This study investigated the antibacterial properties of ethanolic extract from Rhodomyrtus tomentosa (Ait.) Hassk. leaves against Bacillus cereus. Preliminary screening to evaluate the activities of the extract used a paper disc diffusion method against 65 food isolates. The extract produced large inhibition zones in all isolates, ranging from 10 to 18 mm. The results were confirmed by MIC and MBC (16 to 64 and 32 to 256 μg/ml, respectively). Rhodomyr

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Vidal, Jean-François, K. Frölicher, P. Archier, et al. "NEW REFERENCE APOLLO3® CALCULATION SCHEME FOR LIGHT WATER REACTORS – ANALYSIS OF THE BEAVRS BENCHMARK." EPJ Web of Conferences 247 (2021): 06031. http://dx.doi.org/10.1051/epjconf/202124706031.

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In the past few years, developments in the APOLLO3® deterministic code have mainly been devoted to Fast Reactor applications. In this paper, we investigate the possibility of using some of these methods to build an accurate two-step calculation scheme for commercial Pressurized Water Reactors, with application to the BEAVRS benchmark at hot zero power conditions of cycle 1. Our objective is to assess the performances of the best “standard” calculation currently possible with APOLLO3® and to have a starting point for the development of improved transport solvers and innovative calculation schem

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Mirkamandar, Ehsan, Mohammad Reza Shakibaie, Saeed Adeli, Mitra Mehrabani, Mohammad Mehdi Hayatbakhsh, and Saeed Esmailian. "In vitro antimicrobial activity of Salvadora persica extract on Helicobacter pylori strains isolated from duodenal ulcer biopsies." Microbiology Research 3, no. 1 (2012): 9. http://dx.doi.org/10.4081/mr.2012.e9.

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The aim of this study was to evaluate the <em>in vitro</em> antimicrobial activity of a methanolic extract of <em>Salvadora persica</em> solution on <em>Helicobacter pylori</em> isolated from duodenal ulcer. Over 22 strains of H. pylori were isolated from duodenal ulcer from August 2010 to June 2011. The <em>S. persica</em> stem was purchased from a local herb market and finely powdered. Extraction was performed with 60% methanol using a soxhlet extractor for 48 h until the solvent turned colorless while being incubated in an oven at 40°C for 48

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Evensen, O. "An Immunohistochemical Study on the Cytogenetic Origin of Pulmonary Multinucleate Giant Cells in Porcine Dermatosis Vegetans." Veterinary Pathology 30, no. 2 (1993): 162–70. http://dx.doi.org/10.1177/030098589303000209.

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The origin of pulmonary multinucleate giant cells (MGC) in porcine dermatosis vegetans was studied in six Norwegian Landrace pigs ages 4 (male), 5 (female), 6 (female), 10 (female), and 12 (one male, one female) weeks, using an avidin biotin peroxidase and alkaline phosphatase complex immunohistochemical method on sections of formalin- and ethanol-fixed and frozen tissue specimens. Well-characterized, commercially available antisera/monoclonal antibodies to keratin, vimentin, lysozyme, a monocytic antigen, and a myelomonocytic antigen were used. The immunoreactivity to intermediate-sized filam

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Pandey, Aparna, Jagat Bhushan, Rajesh Kumar Joshi, Amandeep Singh Uppal, Archana Angrup, and Shubhangi Kansal. "Comparative evaluation of antimicrobial efficacy of chitosan nanoparticles and calcium hydroxide against endodontic biofilm of Enterococcus faecalis: An in vitro study." Journal of Conservative Dentistry and Endodontics 27, no. 7 (2024): 750–54. http://dx.doi.org/10.4103/jcde.jcde_219_24.

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Aim: The aim of the study was to assess and evaluate the antimicrobial effectiveness of chitosan nanoparticles (CSNPs) with calcium hydroxide in the elimination of Enterococcus faecalis. Materials and Methods: Using the broth microdilution method, the minimum inhibitory concentration (MIC) and minimum bactericidal concentration (MBC) of calcium hydroxide and CSNPs were measured. The antibiofilm effect of calcium hydroxide and CSNPs against E. faecalis biofilm was qualitatively analyzed using a crystal violet assay. A 7-day-old biofilms of E. faecalis grown on dentine discs were assigned to the

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Davies, Sarah I., Mark J. Chang, Gregory Whitehill, et al. "Efficient generation of MCC oncoprotein-specific CD4+ T cells for potential adoptive immunotherapy." Journal of Immunology 200, no. 1_Supplement (2018): 181.19. http://dx.doi.org/10.4049/jimmunol.200.supp.181.19.

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Abstract Merkel Cell Carcinoma (MCC) is an aggressive skin tumor caused by Merkel Cell Polyomavirus (MCV) in ~80% of cases that responds poorly to standard chemotherapies. Virus positive tumors have a low mutational burden, and are driven by alternatively spliced T-antigens (TAG), small T (sT) and truncated large T antigen (LTT). These intracellular proteins are constitutively expressed in MCC tumors and are required for tumor survival. We hypothesized that MCV TAG can be targeted by cytotoxic T lymphocytes for potential use as an adoptive T cell immunotherapy to treat MCC. Peripheral blood T

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Bhatia, Sudhir, and Gudrun Baersch. "Rapid Isolation of Mononuclear Cells with High Yield from Minimal Blood Volumes: A Simplified and Robust Approach for Immunotherapeutic Applications." Medical Science and Discovery 10, no. 10 (2023): 838–41. http://dx.doi.org/10.36472/msd.v10i10.1062.

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Objective: Currently, mononuclear cell (MNC) isolation is performed using density gradient methods, which are laborious and time-consuming, requiring a minimum of 10 ml of buffy coat or blood. This method is inadequate for isolating MNCs from small volumes, such as 100 µl. Therefore, we aimed to develop a straightforward, rapid, and cost-effective method for isolating MNCs from minute volumes of blood and buffy coat. Material and Methods: We utilized the MNC isolator to isolate MNCs from microvolumes, such as 100 µl and 500 µl of blood and buffy coat, by simple mixing and centrifugation. The i

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Hung, Tran Thanh, Pham Thu Trang, Hoang Viet, Nguyen Thi My Lan, Luong Thi My Ngan, and Tran Trung Hieu. "In vitro antimicrobial activity of hydrosol from Litsea cubeba (Lour.) Pers. against Helicobacter pylori and Candida albicans." Biomedical Research and Therapy 7, no. 6 (2020): 3819–28. http://dx.doi.org/10.15419/bmrat.v7i6.610.

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Introduction: Helicobacter pylori and Candida albicans are classified as the most common pathogenic agents in humans. H. pylori is responsible for gastroduodenal diseases and greatly associated with gastric carcinogenesis, while C. albicans is the main cause of fungal urinary tract, genital yeast, and fungal skin infections. The increasing appearance of drug-resistant strains of H. pylori and C. albicans has made the treatment of the infections more serious. Hydrosols from plant steam distillation have been traditionally used in medicine, cosmetics, and culinary uses. They have been recently s

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Balchen, Jens G. "A method for the control of alumina concentration in aluminum reduction cells." Modeling, Identification and Control: A Norwegian Research Bulletin 13, no. 1 (1992): 41–49. http://dx.doi.org/10.4173/mic.1992.1.4.

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Varypataki, Eleni Maria, Thomas M. Kündig, and Pål Johansen. "PCI-based vaccination: a novel method for targeting of MHC class I antigen presentation and stimulation of antigen-specific cytotoxic T cells." Journal of Immunology 198, no. 1_Supplement (2017): 79.25. http://dx.doi.org/10.4049/jimmunol.198.supp.79.25.

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Abstract Cytotoxic CD8+ T cells are key players in fighting cancer and infectious diseases, hence, the design of therapeutic vaccines focuses on ways to prime strong cytotoxic immune responses. Yet, current vaccines efficacy is limited mainly due to the default processing of exogenous antigens via the MHC class II pathway and the activation of CD4+ and not CD8+ T cells. Photochemical internalization (PCI) is a novel intracellular delivery approach, able to circumvent the MHC class II processing. Briefly, after endocytosis of antigen and photosensitizer by antigen presenting cells, light activa

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Borges, Larissa Lorrane Rodrigues, Alécia Daila Barros Guimarães, Fanciellen Morais-Costa, Eduardo Robson Duarte, Márcia Martins, and Roberta Torres Careli. "Efficacy of Caryocar brasiliense Camb. and Annona crassiflora Mart. leaves in the reduction of biotransferred Escherichia coli from Lactuca sativa L. leaves to polypropylene." Research, Society and Development 10, no. 17 (2021): e124101724268. http://dx.doi.org/10.33448/rsd-v10i17.24268.

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The antimicrobial activity of Caryocar brasiliense and Annona crassiflora leaves extracts was evaluated against Escherichia coli strains through a sensitivity test by the agar diffusion method and by the evaluation of minimal inhibitory concentrations (MIC) and minimal bactericidal concentrations (MBC) by the microdilution technique followed by plating. The sanitizing efficiency of these extracts in reducing E. coli cells biotransferred from L. sativa leaves to polypropylene surfaces was evaluated after an exposure time of 5 minutes. All strains were sensitive to antibacterials and the formati

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Nazarchuk, O. A., V. V. Bebyk, T. V. Denysko, and V. V. Nagaichuk. "Study of the Effect of Low-Intensity Currents Without External Power Sources on Planktonic Cells of Multidrug-Resistant Pseudomonas aeruginosa Strains and Their Susceptibility to Antibiotics." Reports of Vinnytsia National Medical University 29, no. 1 (2025): 29–34. https://doi.org/10.31393/reports-vnmedical-2025-29(1)-04.

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Annotation. The global threat of bacterial resistance to antibiotics necessitates the search for alternatives and methods to overcome resistance. The aim of this study was to investigate the antibacterial effect of low-intensity electric current on multidrug-resistant P. aeruginosa strains and to determine its impact on bacterial susceptibility to antibiotics. The effect of electric current was studied on reference and clinical multidrug-resistant strains of P. aeruginosa (n=15) in isotonic solution and meat-peptone broth (MPB), with bacterial concentration measured using a densitometer. The s

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Duarte, Andreia F., Susana Ferreira, Rosário Oliveira, and Fernanda C. Domingues. "Effect of Coriander Oil (Coriandrum sativum) on Planktonic and Biofilm Cells of Acinetobacter baumannii." Natural Product Communications 8, no. 5 (2013): 1934578X1300800. http://dx.doi.org/10.1177/1934578x1300800532.

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The increasing incidence of hospital-acquired infections caused by multi-drug resistant pathogens, such as Acinetobacter baumannii, coupled with the low efficacy of drugs and rising treatment costs has created interest in the potential antimicrobial properties of natural products. The main objective of this work was to determine the effect of coriander essential oil on Acinetobacter baumannii in different growth phases, as well as its ability to inhibit the formation or eradication of biofilms. The minimum inhibitory concentration (MIC) and minimum bactericidal concentration (MBC) of coriander

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Forouzanfar, Fatemeh, Hamideh Sadat Mohammadipour, Majid Akbari, Reza Beyraghshamshir, Abbas Tanhaeian, and Elnaz Karimian. "The Application of a Recombinant Antimicrobial Peptide of Thrombocidin-1 Expressed in Pichia pastoris as a Novel Approach Against Some Oral Pathogenic Bacteria: An In Vitro Study." Protein & Peptide Letters 29, no. 1 (2022): 102–9. http://dx.doi.org/10.2174/0929866528666211126161928.

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Objective: Oral infections and dental caries are considered serious health problems. Therefore, searching for new agents with antimicrobial properties seems to be crucial. This study aimed to evaluate the antimicrobial activity of the recombinant Thrombocidin-1 [TC-1] peptide on some oral pathogens. Also, the cytotoxicity of this peptide on human gingival fibroblast cells was investigated. Methods & Materials: In this study, Pichia pastoris was used for the expression of recombinant TC-1. The microbroth dilution method was used to determine the minimum inhibitory concentration [MIC] and mi

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Sukmawati, Ika Kurnia, Diah Rakhmawati, and Ari Yuniarto. "ANTIFUNGAL ACTIVITY OF EXTRACT AND FRACTION OF AURICULARIA AURICULAR ON CANDIDA ALBICANS, MICROSPORUM GYPSEUM, AND ASPERGILLUS FLAVUS." Asian Journal of Pharmaceutical and Clinical Research 11, no. 13 (2018): 141. http://dx.doi.org/10.22159/ajpcr.2018.v11s1.26591.

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Objective: Indonesia with high humidity and rainfall strongly supports the growth of fungi. The incidence of fungal infections has increased dramatically over the past three decades. Several factors including microbiological resistance led to the failure of antifungal therapy. This research was to evaluate the antifungal activity of extract and fraction of Auricularia auricula against the test fungus.Methods: Antifungal activity was performed by microdilution method using extract and n-hexane fraction, ethyl acetate fraction, methanol, and water fraction of A. auricula. MIC was determined by o

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Fernandes, Maurette dos Reis Vieira, Tales Alexandre Costa e. Silva, Ludwig Heinrich Pfenning, et al. "Biological activities of the fermentation extract of the endophytic fungus Alternaria alternata isolated from Coffea arabica L." Brazilian Journal of Pharmaceutical Sciences 45, no. 4 (2009): 677–85. http://dx.doi.org/10.1590/s1984-82502009000400010.

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A total of 22 endophytic fungi isolated from coffee (Coffea arabica L.) were cultivated in vitro and their crude extracts tested. The screening was carried out using the agar diffusion method against Staphylococcus aureus, Escherichia coli and Candida albicans. The most effective isolate was Alternaria alternata, and subsequently, its extract was assayed. The total phenolic content was 3.44 μg GAE/mg of the crude extract. For the antibacterial and antifungal activity assays, minimum inhibitory concentrations (MIC) and minimum bactericidal and fungicidal concentrations (MBC and MFC) were determ

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Unger, Gretchen M., Beverly R. Wuertz, Mary E. Brown, Sanjana Arji, Janeen H. Trembley, and Frank G. Ondrey. "Abstract 5272: 3D cell-culture strategy for screening novel agents in Fanconi anemia chemoprevention." Cancer Research 83, no. 7_Supplement (2023): 5272. http://dx.doi.org/10.1158/1538-7445.am2023-5272.

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Abstract Fanconi anemia (FA) patients have DNA repair mutations predisposing them to oral cancers so treatment with non-DNA damaging agents is highly desired. As cancer experimental therapeutics advance towards study paradigms that more carefully mimic physiology, e.g. organoids and spheroids. Presently, we are using a 3D cell culture method emphasizing layers of extracellular matrix (ECM) as FA premalignant lesions retain epithelial architecture. We conducted 3D screening studies using 2 layered geometries: 1) nanofibers coated with 1 ng/mL 2:1 Collagen III/IV (C3C4) then 100 pg/mL 2.75:1 Ten

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Garcia-Bernal, David, Miguel Blanquer, Jose Antonio del Rio, et al. "In Vitro Study of New Photochemotherapeutic Compounds for Extracorporeal Photopheresis." Blood 120, no. 21 (2012): 2144. http://dx.doi.org/10.1182/blood.v120.21.2144.2144.

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Abstract Abstract 2144 Introduction: Extracorporeal photopheresis (ECP) is a cell-based immunomodulatory therapy involving the separation of autologous mononuclear cell fraction followed by ex-vivo administration of 8-methoxypsoralen (8-MOP) and UVA irradiation before reinfusion. ECP is efficient for the treatment of cutaneous T-cell lymphomas, multiple skin disorders, autoimmune diseases, solid organ transplant rejection and graft versus host disease (GVDH). During UVA irradiation phase, 8-MOP binds covalently to leukocytes' DNA leading to cell cycle arrest and apoptosis. These pre-apoptotic

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Garcia-Bernal, David, Miguel Blanquer Blanquer, Maria del Carmen Algueró, et al. "Description of New More Effective Photochemotherapeutic Compounds for Improving Effectiveness of Extracorporeal Photopheresis." Blood 124, no. 21 (2014): 4124. http://dx.doi.org/10.1182/blood.v124.21.4124.4124.

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Abstract Introduction: Extracorporeal photopheresis (ECP) is a clinically used cell-based immunomodulatory therapy that involves exposure of peripheral blood autologous mononuclear cells to the photosensitizer 8-methoxypsoralen (8-MOP) and UVA radiation before reinfusion. ECP has demostrated efficacy in the treatment of multiple diseases caused by unregulated T cell populations such as graft-versus-host disease (GvHD). During UVA irradiation, 8-MOP covalently binds to DNA, inducing apoptosis. It has been previously reported that 8-MOP-mediated apoptosis triggers some immumodulatory effects tha

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Ang, Piao Piao, Geok Chin Tan, Norain Karim, and Yin Ping Wong. "Diagnostic Value of the EZH2 Immunomarker in Malignant Effusion Cytology." Acta Cytologica 64, no. 3 (2019): 248–55. http://dx.doi.org/10.1159/000501406.

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Background: Differentiating reactive mesothelial cells from metastatic carcinoma in effusion cytology is a challenging task. The application of at least 4 monoclonal antibodies including 2 epithelial markers (Ber-EP4, MOC-31, CEA, or B72.3) and 2 mesothelial markers (calretinin, WT-1, CK5/6, or HBME-1) are often useful in this distinction; however, it is not readily available in many resource-limited developing countries. Aberrant immunoexpression of enhancer of zeste homolog 2 (EZH2), a transcriptional repressor involved in cancer progression, is observed widely in various malignancy. In this

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Spencer, Bryan P., Indreshpal Kaur, Patrick Fong, et al. "Enrichment of Mononuclear Cells From Cryopreserved Cord Blood Units Using the Purecell” Select System." Blood 114, no. 22 (2009): 2159. http://dx.doi.org/10.1182/blood.v114.22.2159.2159.

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Abstract Abstract 2159 Poster Board II-136 INTRODUCTION: Many procedures for manufacturing clinical products for cellular therapy involve enrichment of mononuclear cells (MNC). The most common procedure is density gradient separation. Disadvantages of this procedure are low yield of cells especially with cryopreserved products and the open events during processing. We evaluated use of the Purecell” Select System (PALL Medical, NY) for enriching MNC from cryopreserved Cord Blood Units (CBU). METHODS: Initial experiments were performed to optimize the system for recoveries of total nucleated cel

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