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Journal articles on the topic 'Method of phonophoresis'

Author: Grafiati

Published: 28 May 2022

Last updated: 31 July 2025

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1

Babaskina, Liudmila Ivanovna, Tatiana Mikhailovna Litvinova, Dmitrii Vladimirovich Babaskin, and Olga Valerevna Krylova. "Control of the Transdermal Delivery Process of Active Substances of the Phytocomplex during Phonophoresis in Model Experiments." Open Access Macedonian Journal of Medical Sciences 7, no. 13 (2019): 2079–83. http://dx.doi.org/10.3889/oamjms.2019.607.

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BACKGROUND: The scientific substantiation for the selection of therapeutically significant dosage of phytocomplex in the dosage form for phonophoresis, control over the delivery of active substances into the body, and what affects this process require the study of the kinetics of phytocomplex flavonoids delivery during phonophoresis. AIM: The aim was to study the possibilities of controlling the process of transdermal delivery of phytocomplex active substances (flavonoids) during phonophoresis in vitro model experiments. METHODS: Working compositions with different concentrations o

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Bukhari, Komal Ammar, Imran Ahmad Khan, Shahid Ishaq, et al. "Formulation and Evaluation of Diclofenac Potassium Gel in Sports Injuries with and without Phonophoresis." Gels 8, no. 10 (2022): 612. http://dx.doi.org/10.3390/gels8100612.

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Background: Pain remains a global public heath priority. Phonophoresis, also known as sonophoresis or ultrasonophoresis, is when an ultrasound is used to maximize the effects of a topical drug. Purpose: The objective of this study was to test, in patients injured in sports or accidents (N = 200), the efficacy of diclofenac potassium (DK) 6%, 4%, and 2% formulated gels with and without phonophoresis in comparison with market available standard diclofenac sodium (DS or DN) gel. Methods: The patients were enrolled after informed consent. By using the lottery method, 100 patients were randomly seg

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Martin-Vega, Francisco Javier, Maria Jesus Vinolo-Gil, Veronica Perez-Cabezas, Manuel Rodríguez-Huguet, Cristina Garcia-Munoz, and Gloria Gonzalez Medina. "Use of Sonophoresis with Corticosteroids in Carpal Tunnel Syndrome: Systematic Review and Meta-Analysis." Journal of Personalized Medicine 12, no. 7 (2022): 1160. http://dx.doi.org/10.3390/jpm12071160.

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Carpal tunnel syndrome is a neuropathic disease. It is one of the most frequent musculoskeletal pathologies affecting the upper limbs. One of most frequently used non-surgical treatments is corticosteorids. There are several alternatives for corticosteroids administration. One of them is phonophoresis, this being an effective and painless method of treatment. A systematic review and meta-analysis have been conducted over the use of phonophoresis with corticosteroids for the treatment of carpal tunnel syndrome compared to other non-surgical treatment methods. Keywords from Medical Subjects Head

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Morsoleto, Felipe Misael da Silva, Pedro Rondon Werneck, Fernando Russo Costa do Bomfim, Marcelo Augusto Marretto Esquisatto, and Maria Jose Misael da Silva Morsoleto. "Therapeutic ultrasound and essential oil of melaleuca alternifolia interfere with muscle regeneration?" Research, Society and Development 11, no. 6 (2022): e10411628791. http://dx.doi.org/10.33448/rsd-v11i6.28791.

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Currently the Essentials oil of Tea Tree is used in healing, for possessing various medicinal properties. Phonophoresis is a method used in physiotherapy, where pharmacological substances associated with a coupling agent, are induced by ultrasonic waves in the underlying tissues. Our objectives are aimed at monitoring and qualitative analysis of the lesion treated with the compound and the method accuracy phonophoresis. We used twenty (20) rats, which are divided into two (2) different groups: Group I: Rats harmed without intervention and Group II: Rats victims treated with the compound by Pho

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Alsharidah, Ashwag S. "Efficacy of gabapentin phonophoresis on post mastectomy intercostobrachial neuralgia." Fizjoterapia Polska 24, no. 2 (2024): 23–27. http://dx.doi.org/10.56984/8zg56084sr.

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Aim. To investigate the efficacy of gabapentin phonophoresis for neuropathic pain management in intercostobrachial neuralgia cases. Material and methods. Fifty-seven females with intercostobrachial neuralgia were randomly collected then allocated into two groups, Study group (gabapentin phonophoresis) and Control group (gabapentin gel). Study group: received gabapentin phonophoresis 4 times/week for 4 weeks (a total of 16 sessions) using continuous ultrasound (1 MHz, 1.5 W/cm², for 5 minutes). Control group: received topical 6% w/w gabapentin gel three times per day for 4 weeks on the affected

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Ead, J. Karim, Arjun Sharma, Miranda Goransson, and David G. Armstrong. "Potential Utility of Ultrasound-Enhanced Delivery of Antibiotics, Anti-Inflammatory Agents, and Nutraceuticals: A Mini Review." Antibiotics 11, no. 10 (2022): 1290. http://dx.doi.org/10.3390/antibiotics11101290.

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Ultrasound technology has therapeutic properties that can be harnessed to enhance topical drug delivery in a process known as phonophoresis. The literature on this method of drug delivery is currently sparse and scattered. In this review, we explore in vivo and in vitro controlled trials as well as studies detailing the mechanism of action in phonophoresis to gain a clearer picture of the treatment modality and explore its utility in chronic wound management. Upon review, we believe that phonophoresis has the potential to aid in chronic wound management, particularly against complicated bacter

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Bordunova, Olga, Evgeniya Samokhina, Leontiі Khmelnychyi, Mykola Povod, and Victoria Vechorka. "ZOOHYGIENIC CHARACTERISTICS OF BIOTECHNOLOGICAL METHODS OF METABOLISM REGULATING OF CHICKENS EMBRYO IN THE PROCESS OF INCUBATION." Bulletin of Sumy National Agrarian University. The series: Livestock, no. 4(43) (December 25, 2020): 100–105. http://dx.doi.org/10.32845/bsnau.lvst.2020.4.15.

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The research presents the results of experimental studies of the influence of various physicochemical factors (phonophoresis, electrophoresis, electrospray, diffusion, etc.) on the rate of transport of biologically active substances through the protective layer of hatchig eggs shell of crossbred Haysex Brown. The aim of the study was to compare the effectiveness of the use of physicochemical methods of transportation of biologically active substances through the shell of hatching eggs of chickens. For the experiment, three batches of eggs were formed, which were obtained from layer hens Haysex

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Bordunova, Olga, Evgeniya Samokhina, Leontiy Khmelnychyi, Mykola Povod, and Victoria Vechorka. "ZOOHYGIENIC CHARACTERISTICS OF BIOTECHNOLOGICAL METHODS OF METABOLISM REGULATING OF CHICKENS EMBRYO IN THE PROCESS OF INCUBATION." Bulletin of Sumy National Agrarian University. The series: Livestock, no. 1(44) (March 29, 2021): 36–41. http://dx.doi.org/10.32845/bsnau.lvst.2021.1.5.

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 The research presents the results of experimental studies of the influence of various physicochemical factors (phonophoresis, electrophoresis, electrospray, diffusion, etc.) on the rate of transport of biologically active substances through the protective layer of hatching eggs shell of crossbred Haysex Brown. The aim of the study was to compare the effectiveness of the use of physicochemical methods of transportation of biologically active substances through the shell of hatching eggs of chickens. For the experiment, three batches of eggs were formed, which were obtained from layer hen

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Syed, Roshni Shanavas, Eswar Reddy K, Harsha Sri Vidya Mandali, Lakshmi Alekhya Dasari, and Rama Krishna Sai Aremanda. "A Study to Compare Phonophoresis with Kinesio Taping in Reducing Pain and Improving Grip Strength in Subjects with Tennis Elbow." International Journal of Health Sciences and Research 15, no. 2 (2025): 288–94. https://doi.org/10.52403/ijhsr.20250238.

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Background: Taping techniques are advocated for musculoskeletal conditions such as Tennis elbow, a prevalent disorder with a significant impact on the individual and community. Little evidence exists supporting the effects of taping techniques on musculoskeletal pain. Therefore, the study aims to determine the effectiveness of a taping technique on pain and grip strength in subjects with tennis elbow. Method: 30 subjects were taken into the study and divided into 2 groups of 15 in each group. Group A subjects were treated with phonophoresis with sodium diclofenac gel of 2% for 5-8 minutes for

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Cagnie, Barbara, Elke Vinck, Steven Rimbaut, and Guy Vanderstraeten. "Phonophoresis Versus Topical Application of Ketoprofen: Comparison Between Tissue and Plasma Levels." Physical Therapy 83, no. 8 (2003): 707–12. http://dx.doi.org/10.1093/ptj/83.8.707.

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Abstract Background and Purpose. Over the last few decades, application of ultrasound has been attempted to enhance transdermal transport of several drugs, a method referred to as “phonophoresis.” The purposes of this study were to examine the influence of ultrasound on the transdermal delivery of ketoprofen in humans and to compare the concentrations found after continuous and pulsed application. Subjects and Methods. Twenty-six patients with knee disorders requiring arthroscopy were randomly assigned to 1 of 3 groups. Just before surgery, phonophoresis of a ketoprofen gel (Fastum gel) was gi

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Kazantseva, Christina V., Sergey N. Nagornev, Valery K. Frolkov, Elena V. Gusakova, and Maria S. Nagorneva. "Clinical efficiency of the combined application of physiotherapeutic technologies and drinking mineral waters in patients with curral skin changes under conditions of insulin resistance." Russian Journal of Physiotherapy, Balneology and Rehabilitation 20, no. 2 (2021): 147–54. http://dx.doi.org/10.17816/1681-3456-2021-20-2-6.

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BACKGROUND: One of the effective and pathogenetically substantiated methods of therapeutic action on cicatricial changes in the skin are laser technologies in combination with collagenases. However, as previous studies have shown, the presence of metabolic syndrome in patients significantly reduces the clinical efficacy of the combined use of laser therapy and phonophoresis of Fermencol. The most reasonable solution in this situation can be scientific research and experience in the practical use of drinking mineral waters, which have a high corrective efficiency in relation to metabolic proces

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ADAMBAEV, Zufar, Ibodulla KILICHEV, and Tuygunoy XODJANOVA. "EXPERIENCE OF CONSERVATIVE TREATMENT OF INTERVERTEBRAL DISC HERNIAS WITH CARIFLEX GEL AND CREAM IN AMBULATORY CONDITIONS." JOURNAL OF NEUROLOGY AND NEUROSURGICAL RESEARCH 3, no. 1 (2020): 6–8. http://dx.doi.org/10.26739/2181-0982-2020-3-1.

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A complex therapy of patients with degenerative-dystrophic diseases of the spine with herniated intervertebral discs with neurological manifestations was carried out with the addition of phonophoresis Kariflex gel followed by segmental massage with Kariflex cream. The comparative evaluation of the method was carried out in 89 patients. Comparative analysis revealed the reliable efficiency of the method used. Against the background of the proposed therapy, there was a significant decrease in pain and muscle-tonic syndromes, an increase in the range of motion in the spine

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Krotov, S. Yu, Yu T. Ignat’ev, and Yu A. Krotov. "Tympanic cavity ultraphonophoresis in cases of preserving integrity of tympanic membrane." Russian Otorhinolaryngology 20, no. 1 (2021): 51–55. http://dx.doi.org/10.18692/1810-4800-2021-1-51-55.

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One of the most common treatments for the middle ear disorders is the injection of medications into the tympanic cavity through the acoustic meatus. This method has proven itself in treatment of the perforated forms of otitis. In cases of preserving the integrity of the tympanic membrane, its efficacy is arguable due to the impossibility of drug direct penetration via the membrane and contact with the mucous membrane. To increase the permeability of the tympanum, the authors used endaural phonophoresis of drugs. The drug penetration into the tympanum was confirmed by multispiral computed tomog

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Iordan, Daniel-Andrei, Ilie Onu, Daniela-Viorelia Matei, et al. "Effect of hydrocortisone ultrasonic phonophoresis in the treatment of knee osteoarthritis." Balneo and PRM Research Journal, Vol.14, no.3 (September 1, 2023): 575. http://dx.doi.org/10.12680/balneo.2023.575.

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Background: Knee Osteoarthritis (KOA) is a frequent type of degenerative joint disease, which results in a gradual loss of function, discomfort, and stiffness. KOA can be effectively treated with oral drugs such as corticosteroids and nonsteroidal anti-inflammatory drugs (NSAIDs). NSAIDs may raise the dangers of renal, gastrointestinal, and other systemic toxicities. Compared with oral NSAIDs, topical gels are an alternative therapeutic option with fewer side effects, with less therapeutic efficacy. Studies on ultrasound (US) as a therapeutic method go back a long time in KOA. US not only reli

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Samoilova, I. A., B. G. Sadykov, I. F. Fatkullin, and R. I. Gabidullina. "Use of low-frequency ultrasound for the prevention of inflammatory complications after cesarean section." Kazan medical journal 78, no. 6 (1997): 447–50. http://dx.doi.org/10.17816/kazmj83689.

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The ultrasound sanation method of peritoneum in 103 operations of cesarean section is used to decrease the number of postoperative complications. As a result of it the number of postoperative complications decreased by a factor of six, the necessity of preventive antibacterial therapy was excluded. The best results are obtained after ultrasound sanation in solutions of dimephospone and antibiotics that perhaps is associated with phonophoresis of medicinal agents in tissue immediately in infection. The use of ultrasound sanation is indicated in operative delivery of pregnants with increased ris

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Filatov, V. V., E. I. Sidorenko, and N. V. Filatova. "STUDY OF THE RADIOPHARMACEUTICALS DISTRIBUTION INTENSIVENESS UNDER INFLUENCE OF INFRASOUND IN THE EXTERIOR TUNICS AND INTERIOR OCULAR STRUCTURES IN POSTERIOR (RETROBULBAR) AND ANTERIOR (NON-INJECTION) METHODS OF REMEDIES ADMINISTRATION." Russian Pediatric Ophthalmology 5, no. 2 (2010): 34–37. https://doi.org/10.17816/rpoj37453.

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The article presents the data on the comparative study of efficiency of medications penetration and accumulation in the eye under the effect of a new method of infrasonic phonophoresis in retrobulbar and anterior non-injection way of radiopharmaceuticals administration with the following infrasonic impact on the eye during 10 minutes with frequency 4 Hz, power 173 dB in the live pressure mode of operation. The study was performed in 40 chinchilla rabbits (80 eyes). The obtained data is an evidence that under the impact of infrasound a significant accumulation of radiopharmaceuticals occur insi

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Taheri, Parisa, Razieh Maghroori, and Aidin Heidari. "Assessment of Kinesio Taping Versus Phonophoresis for the Treatment of Painful Hallux Valgus: A Pilot Study." Galen Medical Journal 10 (May 12, 2021): 1888. http://dx.doi.org/10.31661/gmj.v10i0.1888.

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Background: Hallux valgus (HV) is a deformity that affects the quality of life and function in a negative manner causing disturbed balance and walking and even alters the foot kinematics. Conservative treatments are the choice for mild to moderate HV, but the question about the best method has not been responded yet. In the current study, it is aimed to assess and compare the efficacy of kinesiotaping (KT) versus phonophoresis (PH) for the treatment of painful HV. Materials and Methods: This randomized clinical trial has been conducted on a total number of 37 toes (37 toes of a total number of

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Nikolaeva, G. V. "The use of infrasonic pneumomassage in ophthalmology." Russian ophthalmology of children 52, no. 2 (2025): 37–41. https://doi.org/10.25276/2307-6658-2025-2-37-41.

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Abstract Purpose. Presentation of the main achievements of the scientific school of pediatric ophthalmologists of the N.I. Pirogov Russian National Research Medical University on the development and implementation of infrasonic pneumomassage into ophthalmological clinical practice. Material and methods. А review of scientific publications and dissertation research works performed by employees of the Department of Ophthalmology of the Institute of Motherhood and Childhood of the N.I. Pirogov Russian National Research Medical University under the leadership of the head of the department, corresp

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Nuery, Dr Nuzhat, Dr Sohely Rahman, Dr Md Arifur Rahman Chowdhury, Dr Md Aminul Alam, and Dr Mohammed Kamruzzaman. "Comparison of the Efficacy of Intra-Articular Cortevcosteroid Injection and Phonophoresis in the Treatment of Adhesive Capsulitis." Saudi Journal of Medicine 10, no. 01 (2025): 11–16. https://doi.org/10.36348/sjm.2025.v10i01.003.

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Background: The term ‘frozen shoulder’ should be reserved for a well-defined disorder characterized by progressive pain and stiffness of shoulder which usually resolves spontaneously after about 18 months. The objectives of treatment are to relieve pain and thus restore motion and function of shoulder. Recommended treatment approaches are physical therapy, local and systemic corticosteroid, anti-inflammatory drugs, antidepressants, nerve blocks and manipulation under anesthesia. Objective: Compare the efficacy of intra-articular corticosteroid injection and phonophoresis in the treatment of Ad

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Pratiwi, Jihan Nur, and Khoirun Nisa. "Terapi Komplementer Akupuntur Terhadap Penderita Sindroma Terowongan Karpal." Jurnal Penelitian Perawat Profesional 1, no. 1 (2019): 95–102. http://dx.doi.org/10.37287/jppp.v1i1.28.

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Sindroma Terowongan Karpal (Carpal Tunnel Syndrome atau CTS) adalah kondisi kompresi saraf medianus pada terowongan karpal sehingga muncul gejala klinis berupa kekakuan, paresthesia, dan nyeri. Beberapa intervensi perawatan baik konservatif dan bedah diusulkan untuk pengobatan CTS. Intervensi konservatif termasuk bebat, injeksi steroid lokal, carpal tunnel release, steroid oral atau ketoprofen phonophoresis, efektif pada pasien dengan gejala ringan sampai sedang. Sementara pembedahan disarankan jika intervensi konservatif gagal. Di antara intervensi tersebut, akupuntur telah mendapat perhatian

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Olesov, Egor E., Dmitry I. Morozov, Alexander G. Volkov, Nataliya Zh Dikopova, and Anna G. Ponomareva. "Determination of the minimum suppressing concentration to metronidazole in representatives of obligate and optional anaerobic microflora of periodontal pockets." Russian Journal of Dentistry 25, no. 1 (2021): 54–58. http://dx.doi.org/10.17816/1728-2802-2021-25-1-54-58.

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BACKGROUND: Due to the long period of use of metronidazole in medical dental practice, today it is relevant to study the sensitivity and the minimum inhibitory concentration of reference and clinical strains of obligate anaerobic microbiota to metronidazole in periodontitis. AIM: Determination of sensitivity and minimum suppressive concentration of reference and clinical strains of obligate anaerobic microbiota to metronidazole in periodontitis. MATERIALS AND METHODS: Strains of obligate anaerobic microbiota of periodontal pockets with moderate periodonitis were isolated from 30 pa

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Egorov, E. A., T. B. Romanova, and E. G. Rybakova. "Prospects for the use of contact lenses in pharmacotherapy of eye diseases (review). Part 1. Development of an idea of prolonged non-invasive drug administration into the ocular tissues and cavity." Russian Journal of Clinical Ophthalmology 25, no. 1 (2025): 36–41. https://doi.org/10.32364/2311-7729-2025-25-1-5.

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Local pharmacotherapy is one of basic ophthalmological therapeutic methods (especially, in case of diseases affecting an anterior ocular segment). A main advantage of local therapeutic methods is a drug efficiency associated with the minimum side effect or its absence. The review addresses an important issue of ophthalmotherapy: how to improve efficient and safe drug administration methods? In particular, a search for methods of their prolonged intraocular administration is of special interest. The Part 1 of the review discusses conventional methods of non-invasive eye treatment such as drops,

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Zuhri, Saifudin. "Pengaruh Phonophoresis Untuk Menurunkan Nyeri Pasien Osteoarthritis Lutut." Jurnal Keterapian Fisik 4, no. 2 (2019): 85–91. http://dx.doi.org/10.37341/jkf.v4i2.191.

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Background: In everyday life activities human beings need prime conditions to create functional motion. One factor that interferes with functional motion is pain. The goal of physiotherapy for people with pain is to relieve pain. Many of the physiotherapy modalities recommended for reducing pain include phonophoresis. But the phonophoresis modality has not been widely implemented in Indonesia. Objective: To determine the effect of phonophoresis on reducing knee pain in patients with knee osteoarthritis. Methods: This study was a pure experiment with a pre-test and post-test with control group

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Kelle, Bayram, Volkan Deniz, and Emine Aygül Ortaç. "Phonophoresis treatment of subacromial impingement syndrome: Pulsed or continuous: A randomized-controlled clinical trial." Turkish Journal of Physical Medicine and Rehabilitation 69, no. 2 (2023): 230–38. http://dx.doi.org/10.5606/tftrd.2023.10996.

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Objectives: This study aims to compare the effectiveness of pulsed and continuous modes of therapeutic ultrasound (US) for phonophoresis in the treatment of subacromial impingement syndrome (SAIS). Patients and methods: Between April 2019 and January 2021, a total of 66 patients with SAIS (17 males, 49 females; mean age: 48.2±8.6 years; range, 19 to 64 years) were included. The patients were randomized to the phonophoresis with continuous mode group (n=22), phonophoresis with pulsed mode group (n=22), and phonophoresis with sham US group (n=22). Five grams of ibuprofen phonophoresis was applie

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Hsieh, Yueh-Ling. "Effects of Ultrasound and Diclofenac Phonophoresis on Inflammatory Pain Relief: Suppression of Inducible Nitric Oxide Synthase in Arthritic Rats." Physical Therapy 86, no. 1 (2006): 39–49. http://dx.doi.org/10.1093/ptj/86.1.39.

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Abstract Background and Purpose. The direct effects of ultrasound (US) and phonophoresis of a nonsteroidal anti-inflammatory drug (NSAID) on injured peripheral tissue have been widely investigated, but evidence concerning the effects of central spinal nociceptive modulation seems to be lacking. The purpose of this study was to investigate the peripheral influences of US and phonophoresis on the modulation of spinal inducible nitric oxide synthase (iNOS) expression elicited by hind paw stimulation with an ankle injection of complete Freund adjuvant (CFA). Subjects and Methods. Inflammatory arth

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K., Mohamed Faisal C., Mary Sumila, Lawrence Mathias, and Ajith S. "COMPARATIVE STUDY ON THE EFFECTIVENESS OF LOW LEVEL LASER THERAPY VERSUS PHONOPHORESIS IN THE MANAGEMENT OF LATERAL EPICONDYLITIS." Journal of Health and Allied Sciences NU 03, no. 01 (2013): 35–44. http://dx.doi.org/10.1055/s-0040-1703631.

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Abstract Background and Objectives: The use of electro physical agents for the management of any soft tissue injuries in Physical Therapy practice is very common for an early recovery from the injury. Among that, Low Level Laser Therapy (LLLT) and Phonophoresis are found to be very effective in soft tissue injuries. So the objective of this study is to know the comparative effectiveness of LLLT versus Phonophoresis in the treatment of lateral epicondylitis. Methods: Convenient sample of 40 patients with lateral epicondylitis were recruited for this study. They were assigned equally either to a

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Maghroori, Razieh, Shiva Fakhari, and Parisa Taheri. "Phonophoresis Plus Topical Nitroglycerin or Hydrocortisone for the Management of Plantar Fasciitis, Which Topical Agent is Superior?" Galen Medical Journal 10 (June 22, 2021): 2072. http://dx.doi.org/10.31661/gmj.v10i0.2072.

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Background: Plantar fasciitis (PF) is the most common reason for inferior heel pain. Various approaches have been raised for the treatment of PF; however, none had substantial outcomes. The current study aims to assess and compare phonophoresis outcomes plus topical nitroglycerin versus phonophoresis plus topical hydrocortisone for PF management. Materials and Methods: The current study has been conducted on 65 patients with PF diagnosis, among whom underwent ten every-other-day sessions of treatment with phonophoresis plus 20 mg nitroglycerin (n=33) or 20mg hydrocortisone (n=32), respectively

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yigman, Zeynep, Nihal Tezel, Ebru Umay, and Damla Cankurtaran. "Title: How should we use corticosteroids in lateral epicondylitis? Local injection or phonophoresis? Running title: Corticosteroid use in lateral epicondylitis." Annals of Medical Research 30, no. 9 (2023): 1. http://dx.doi.org/10.5455/annalsmedres.2023.08.220.

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Objective: This study, it was aimed to compare and evaluate the effectiveness of local corticosteroid injection and corticosteroid phonophoresis on grip strength, functional status, pain, and quality of life in lateral epicondylitis. Materials and Methods: Patients with a diagnosis of lateral epicondylitis who underwent corticosteroid phonophoresis or local corticosteroid injection were included in the study. Patients were grouped according to the treatment they received. In the first group, corticosteroid phonophoresis was applied to the lateral epicondyle region using a continuous mode ultra

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Alam, Aftab, Manjunath U. Machale, Rajkumar Prasad Yadav, Mukesh Sharma, and Akshay Kumar Patel. "Role of Transdermal Drug Delivery System." Asian Journal of Pharmaceutical Research and Development 9, no. 3 (2021): 137–43. http://dx.doi.org/10.22270/ajprd.v9i3.976.

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For several decades, many drug types, including tablets, capsules, pills, creams, ointments, liquids, injectables, have been used for the treatment of disease. These dosage forms must be taken multiple times a day to maintain the concentration of the medication. Transdermal drug delivery systems (TDDS), also known as “patches,” are dosage forms Built to deliver a therapeutically efficient quantity of medicine through the skin of a patient. By increasing patient compliance and preventing first pass metabolism, transdermal delivery offers a leading edge over injectables and oral routes. Transder

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Wu, Yu, Shibo Zhu, Zenghui Lv, et al. "Effects of therapeutic ultrasound for knee osteoarthritis: a systematic review and meta-analysis." Clinical Rehabilitation 33, no. 12 (2019): 1863–75. http://dx.doi.org/10.1177/0269215519866494.

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Objective: To assess the effectiveness and safety of therapeutic ultrasound with sham ultrasound on pain relief and functional improvement in knee osteoarthritis patients. As phonophoresis is a unique therapeutic ultrasound, we also compared the effects of phonophoresis with conventional non-drug ultrasound. Data sources: PubMed, EMBASE, and the Cochrane Library were systematically searched for randomized controlled trials from inception up to June 2019. Review methods: Randomized controlled trials comparing therapeutic ultrasound with sham ultrasound in knee osteoarthritis patients were inclu

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Abo Sabee, Mai Mahmoud, Amal Mohamed Abd El Baky, Tarek Ahmed Amer, and Nessrin Afify Abd El Rasheed. "Cryotherapy versus corticosteroid phonophoresis in the treatment of keloid scars: A randomized clinical trial." Fizjoterapia Polska 23, no. 3 (2023): 70–75. http://dx.doi.org/10.56984/8zg143318.

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Background. Keloid scars negatively impact patients' physical and mental well-being, causing pain and itching. Several methods exist for treating keloids by modulating and improving scar characteristics. Purpose. To investigate and compare the effects of cryotherapy and corticosteroid phonophoresis on patients with keloid scars. Methods. This was a randomized clinical trial. Sixty patients, both male (28) and female (32), with keloid scars were divided into two equal groups. Group A received cryotherapy for 12 weeks (n=30), while Group B underwent corticosteroid phonophoresis for the same dura

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Mohamed, Ahmed Mahmoud, Ashraf Hassan Mohamed Sliman, Noha Gohdan Hussein, and Mona Ebrahim Morsy. "Influence of Tonifying Selected Body Meridians by Low Level Laser and Phonophoresis on Mechanical Neck Pain." Journal of Neonatal Surgery 14, no. 7S (2025): 591–95. https://doi.org/10.52783/jns.v14.2457.

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Background: Body meridians, also known as energy pathways, are a foundational concept in traditional Chinese medicine (TCM) Purpose of the study: The purpose of this study was to evaluate the relationship between some selected body meridians and mechanical neck pain patients. Materials and Methods: There were 60 volunteers with mechanical neck pain of both genders. Their ages ranged from 20 to 40. They were divided into four equal four groups received treatment on meridians. The pressure algometer measures the level of discomfort. Results: pain intensity decreased significantly after treatment

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Maher, Ahmed Elkeblawy, Mohamed Mashaly Mohamed, and Ramzy Lahseen Yasser. "LONG TERM EFFECT OF RADIAL SHOCKWAVE THERAPY VERSUS PHONOPHORESIS IN CHRONIC PLANTAR FASCIITIS: "RANDOMIZED CONTROLLED STUDY"." REVISTA IBEROAMERICANA DE PSICOLOGÍA DEL EJERCICIO Y EL DEPORTE 18, no. 4 (2023): 386–92. https://doi.org/10.5281/zenodo.8404040.

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Purpose: to look into the impacts of shock wave therapy versus phonophoresis in chronic plantar fasciitis. Subjects: sixty-three patients having unilateral chronic plantar fasciitis. Design: pre and post Randomized Control Trial. Methods: The patients were randomly assigned to Group A who received Radial Shockwave Therapy (2000 SWs energy intensity between 0.25 and 0.35 mJ/mm) at (frequency= 10Hz) for 4 weeks 1 session per week additional to conventional treatment. Group B received ultrasound ketoprofen phonophoresis continuous mode, base frequency of 1MHz, power 2 w/cm2, applied for three min

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Habib, Muhammad Soban, Yasir Ali Kazmi, Nasiba Mumtaz, et al. "COMPARATIVE EFFICACY OF FLURBIPROFEN PHONOPHORESIS VERSUS MANUAL TOPICAL GEL APPLICATION IN PATIENTS WITH PLANTAR FASCIITIS IN FAISALABAD." Insights-Journal of Health and Rehabilitation 3, no. 3 (Health & Allied) (2025): 598–604. https://doi.org/10.71000/h5sn5682.

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Background: Plantar fasciitis is a prevalent cause of heel pain that significantly impairs mobility and quality of life. Topical nonsteroidal anti-inflammatory drugs (NSAIDs) like flurbiprofen provide symptomatic relief but often suffer from limited dermal penetration. Phonophoresis, which utilizes therapeutic ultrasound to enhance transdermal drug delivery, may overcome this limitation by improving tissue absorption and accelerating clinical outcomes. This study aimed to evaluate the comparative effectiveness of flurbiprofen delivered via phonophoresis versus manual application in managing pl

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Rahman, H. N. Masuk, Asiful Haque, Mohammed Emran, and A. K. Ahmad Zaman. "Conservative Treatment Alone and with Diclofenac Sodium Phonophoresis on The Patients With Low Back Pain Due to Prolapsed Lumbar Intervertebral Disc." KYAMC Journal 13, no. 3 (2022): 158–64. http://dx.doi.org/10.3329/kyamcj.v13i3.63204.

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Background: Prolapsed lumbar intervertebral disc (PLID) one of the major causes of low back pain. The PLID has become an important and increasingly general health problem, both in Bangladesh and across the world. Phonophoresis has been used clinically since the early 1960s in attempts to drive these drugs transdermally into subcutaneous tissues. The efficacy of Phonophoresis has not been conclusively established in PLID linked low back pain. Objective: To evaluate the effects of Diclofenac Sodium Phonophoresis on patients with low back pain due to PLID. Materials and Methods: The comparative s

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Sanjel Chhetri, Rajendra, Kishor Prashad Khatri, Jagadish Khanal, and Milan KC. "Outcome of Needle Fenestration, Subacromial Steroid and Diclofenac Phonophoresis in Acute Calcific Tendinitis of Shoulder." Journal of Nepal Medical Association 56, no. 207 (2017): 357–61. http://dx.doi.org/10.31729/jnma.3280.

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Introduction: Acute calcific tendinitis of shoulder is very painful and disturbing condition. There are many modalities with variable outcome to address the condition. We studied needling technique with multiple fenestration, subacromial steroid and diclofenac phonophoresis and evaluated the outcome in term of pain relief and improvement of shoulder function at a simple outpatient clinical set up without image or ultrasound guidance. Methods: We studied 18 cases of acute calcific tendinitis presenting within one week from onset of symptoms and X-ray showing calcific deposit. All underwen

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Ismailyan, Kristina V., Larisa S. Kruglova, Sergey N. Nagornev, and Valery K. Frolkov. "Clinical efficacy of the combined use of a pulsed dye laser and enzyme preparation phonophoresis in patients with immature hypertrophic skin scars." Russian Journal of Physiotherapy, Balneology and Rehabilitation 21, no. 4 (2022): 245–54. http://dx.doi.org/10.17816/rjpbr115042.

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BACKGROUND: Taking into account the role of angiogenesis processes in the zone of development of immature scar tissue, it seems pathogenetically justified to use a vascular laser for the correction of hypertrophic skin scars that are at the maturation stage. In this regard, we used a pulsed dye laser, the effect of which is perceived by the patient without pronounced pain, and the technology itself is quite safe and leads to a rapid recovery of the skin after the procedure. Fermencol phonophoresis supplementation of laser therapy with pulsed dye laser has the potential to enhance the therapeut

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Sabharwal, Roopika, Amandeep Singh, Nitin Kumar Saluja, Thakur Gurjeet Singh, and Debarshi Ghosh. "Enhancement of Transdermal Absorption of drugs via Phonophoresis and TENS: An in vitro Study." Journal of Neonatal Surgery 14, no. 8 (2025): 290–94. https://doi.org/10.63682/jns.v14i8.7138.

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Background: Neuromusculoskeletal pain is a complex condition often requiring multifaceted approaches for effective management. Gabapentin is frequently prescribed for such conditions due to its ability to modulate nerve transmission. However, systemic administration may lead to significant side effects. Enhancing transdermal drug delivery via non-invasive modalities presents a novel strategy for local pain control with minimized systemic risks. Objective: The aim of this study was to compare the effectiveness of Phonophoresis (ultrasound-assisted) and Transcutaneous Electrical Nerve Stimulatio

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Al-Zamil, Mustafa Kh, Maria А. Stepanovich, Natalia G. Kulikova, and Ekaterina S. Vasilieva. "The effectiveness of ultrasound therapy and phonophoresis in the treatment of ankylosing spondylitis." Russian Journal of Physiotherapy, Balneology and Rehabilitation 21, no. 4 (2022): 273–80. http://dx.doi.org/10.17816/rjpbr111869.

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BACKGROUND: In Bekhterev's disease, an autoimmune inflammatory process develops in the intervertebral joints and paravetebral muscles and leads to severe pain syndrome and progressive fusion of articular surfaces. Anti-inflammatory and analgesic therapy should be carried out daily with the use of large doses of nonsteroidal anti-inflammatory drugs. With the progression of the disease, drug therapy is not effective enough to relieve pain and to restore the volume of movement in the joints. In this regard, the use of non-drug treatment is a necessary measure for the treatment of such patients.&#

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Rachappa Muragod, Anil, Anil S. Harugop, Kirti Khemlapure, Krupa Varahmurty, and Mussarrat Begum Jamkhanewale. "EFFECT OF NADIFLOXACIN PHONOPHORESIS AND PULSED ULTRASOUND IN SUBJECTS WITH ACUTE SINUSITIS- A RANDOMIZED CLINICAL TRIAL." International Journal of Advanced Research 8, no. 9 (2020): 1179–82. http://dx.doi.org/10.21474/ijar01/11773.

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Aim: To find effectiveness of nadifloxacin phonophoresis over pulsed ultrasound in acute sinusitis subjects. Methods: Study was approved by Institutional Ethical Committee of KAHER Institute of Physiotherapy, Belagavi.40subjects with acute sinusitis were divided randomly into group A, treated with nadifloxacin phonophoresis and group B, treated with pulsed ultrasound. Subjects were assessed using Sinusitis Symptom Score, Numerical Rating scale and Sino-nasal outcome test-22 before and after 4 days of intervention. Result: For sinusitis symptom measure within the groups, mean difference were 6.

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Azam, Insha, Aksh Chahal, Gaurav Kapoor, et al. "Effects of a program consisting of strain/counterstrain technique, phonophoresis, heat therapy, and stretching in patients with temporomandibular joint dysfunction: A pilot study." Medicine 102, no. 32 (2023): e34569. http://dx.doi.org/10.1097/md.0000000000034569.

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Background: The present study was conceptualized as a pilot study to examine the effects of a 3-week program consisting of strain/counterstrain technique (SCST), phonophoresis, heat therapy, and stretching exercises on pain and functions in patients with temporomandibular dysfunction (TMD). Methods: Seven participants (mean age 25.85 years) diagnosed with TMD having pain in the temporomandibular joint (TMJ) area with decreased jaw opening were recruited for the study. Treatment interventions consisting of SCST, phonophoresis (ultrasound gel mixed with diclofenac gel), heat therapy, and stretch

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Elfeky, Heba M., Ahmed М. Elfahl, and Maha G. Ibrahim. "Bee venom phonophoresis on mild to moderate localized plaque psoriasis on a knee joint: a randomized controlled trial." Bulletin of Rehabilitation Medicine 23, no. 5 (2024): 61–69. http://dx.doi.org/10.38025/2078-1962-2024-23-5-61-69.

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Introduction. In psoriasis, plaque psoriasis is the most common kind. Patients may experience mild to severe symptoms, and while the sickness is not lethal, it is difficult to cure. Aim. The purpose of this study is to evaluate the efficacy of bee venom phonophoresis in treating mild to moderate plaque psoriasis of the knee. Materials and methods. Group A received bee venom phonophoresis in conjunction with conservative care, group B received bee venom topical application in conjunction with conservative care, and group C served as a control in a double-blind randomized controlled experiment i

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Faızal Asan, Mohamed, Shruthi Hegde, and Vıdya Ajıla. "Evaluation of Plain Ultrasound Therapy versus Diclofenac Phonophoresis for the management of Temporomandibular Joint Disorders." Cumhuriyet Dental Journal 27, no. 2 (2024): 85–91. http://dx.doi.org/10.7126/cumudj.1383141.

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Objective: Temporomandibular joint disorders (TMD) are one of the most common causes of Chronic orofacial pain. Management of TMD includes various invasive and non-invasive methods. The present study was undertaken to compare the efficacy of plain ultrasound therapy and 1% diclofenac gel phonophoresis in the management of TMDs. Materials and Methods: 50 subjects with pain in the TMJ region, falling in Research Diagnostic Criteria (Group I and II) for TMJ disorders and in the age group of 18-40 years were included in the study. Subjects were divided into 2 groups by simple randomization. Group

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Ismailyan, Kristina V., Sergey N. Nagornev, Larisa S. Kruglova, and Valery K. Frolkov. "The role of matrix metalloproteinases and their tissue inhibitors in the formation of hypertrophic skin scars with the use of a pulsed dye laser and Fermencol phonophoresis." Russian Journal of Physiotherapy, Balneology and Rehabilitation 21, no. 6 (2023): 419–27. http://dx.doi.org/10.17816/rjpbr115953.

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BACKGROUND: An imbalance between matrix metalloproteinases (MMPs) expression and tissue inhibitors of MMP is considered as a possible mechanism for impaired collagen synthesis and degradation, which leads to the development of hypertrophic scars. The use of a vascular laser, in particular a pulsed dye laser, leads to coagulation of the vascular locus that feeds the hypertrophic skin scar, resulting in a decrease in extracellular matrix synthesis. The use of collagenase phonophoresis increases the effectiveness of laser therapy due to the destruction of the extracellular matrix. AIM: To s

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Bumin, Gonca, and Filiz Can. "Effects of iontophoresis and phonophoresis methods on pain in cases with shoulder periarthritis." Pain Clinic 13, no. 2 (2001): 159–62. http://dx.doi.org/10.1163/156856901753421025.

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Roheym, Mohamed I., Mona E. Morsy, Mahmoud Saber, Alaa A. Balbaa, and Abdullah M. Al-Shenqiti. "Comparative study of the effectiveness of high-power laser and ketoprofen phonophoresis in chronic knees osteoarthritis." Fizjoterapia Polska 23, no. 4 (2023): 196–201. http://dx.doi.org/10.56984/8zg20a658.

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Background. Osteoarthritis is one of the major causes of disability and reduced quality of life. characterized by progressive joint degeneration. It decreases the flexibility of the joint, and causes pain, joint effusion, deformities and loss of function. Objective. To investigate the effectiveness of phonophoresis and high-power laser therapy on bilateral knees osteoarthritis. Design. A prospective randomized double-blind trial. Setting. Outpatient Swiss physical therapy center. Methods. Thirty patients from both genders, with their age ranging from 50-65 years that had diagnosed bilateral kn

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Singh, Anshika, Sumit Raghav, Latika Gulyani, Gunjan Chaudhary, and Anirudh Srivastava. "Effects of diclofenac sodium gel phonophoresis in sports activities induced grade-l ankle sprain." Physical rehabilitation and recreational health technologies 8, no. 4 (2023): 203–10. http://dx.doi.org/10.15391/prrht.2023-8(4).05.

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Purpose: the purpose of this study was to evaluate the effect of diclofenac sodium gel phonophoresis in grade -l ankle sprain. Materials & Methods: 54 patients were randomly included in this study and allocated equally into two groups. Group-1 was managed with therapeutic ultrasound (digital ultrasound machine, a product of HMS marketed in India with frequency of 1 MHz and 3MHz) with diclofenac sodium gel and group-2 was managed with therapeutic ultrasound with aquasonic gel. Therapeutic ultrasound with diclofenac sodium gel, marketed under the name of Voltaren, was administered at a frequ

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Filatova, Elena Vladimirovna, Irina Ivanovna Ivanova, Olga Aleksandrovna Bulakh, Olga Viktorovna Trunova, and Marina Valentinovna Supova. "The experience of using fermenkol phonophoresis in complex therapy of carpal tunnel syndrome." Fizioterapevt (Physiotherapist), no. 2 (February 1, 2021): 38–44. http://dx.doi.org/10.33920/med-14-2104-05.

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The issue of compression ischemic syndromes, in particular, carpal tunnel syndrome, is currently extremely relevant. Prolonged compression of the nerve leads to irreversible consequences and degeneration of its fibers, followed by neurogenic muscle atrophy and permanent loss of function. Standard medical and physical therapy methods of treatment do not always achieve a positive effect. The paper considers the results of the use of phonophoresis of hydrocortisone and fermenkol in 35 patients with carpal tunnel syndrome. Positive dynamics was noted in both groups, which increases the possibility

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Rumyantseva, E., A. Yarikov, A. Baitinger, et al. "Increasing the Efficiency of Thermoelectric Conversion of Solar Energy." Bulletin of Science and Practice 10, no. 10 (2024): 98–125. http://dx.doi.org/10.33619/2414-2948/107/12.

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The main etiological factors of nerve damage to the head and neck include injuries, oncological diseases, iatrogenic injuries during surgical interventions. An important task of treatment is to restore the lost function of the nervous head and neck, the functions of which certainly determine the quality of life of the patient. The article presents modern methods of nerve reconstruction of the head and neck. The methods of reconstructive surgery of the facial, trigeminal, inferior alveolar, lingual, recurrent laryngeal nerves are described. This article also describes the types of rehabilitatio

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Kulikova, Natalya G., Mustafa Kh Al-Zamil, Numman Yu Mansur, Albina S. Tkachenko, and Pavel V. Naydenov. "Multifactorial physiotherapy and dynamic modeling of femoral head in post-contusion femoroacetabular impingement of knee joint (case report)." Russian Journal of Physiotherapy, Balneology and Rehabilitation 24, no. 3 (2025): 208–15. https://doi.org/10.17816/rjpbr653387.

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BACKGROUND: The growing number of patients requiring restoration of ligament function in the knee joint due to sports injuries highlights the relevance of developing non-pharmacological rehabilitation methods. The clinical profile of the patient (young age, complicated course of an unconfirmed sports-related injury), as well as the broader objective of improving national health and quality of life, underscore the relevance of systemic analysis in the training of medical personnel within the framework of professional development and scientific research on sports testing methodologies. AIM: The

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