Academic literature on the topic 'Methods Biskind'

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Journal articles on the topic "Methods Biskind"

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Sharma, Aanchal, Hardeep Kataria, and Fahar Merchant. "Abstract 708: Characterization of MDNA132, an IL-13 decoy receptor selective superkine for targeted delivery of immunotherapies to the tumor microenvironment." Cancer Research 83, no. 7_Supplement (2023): 708. http://dx.doi.org/10.1158/1538-7445.am2023-708.

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Abstract Background: Interleukin-13 (IL-13) exhibits high affinity for the IL-13 decoy receptor (IL13Rα2) but retains binding to IL13α1, a component of the functional Type II IL4R complex (IL4Rα/IL13Rα1) that elicits a Th2 immune response. IL13Rα2 expression is limited in normal tissues but is highly overexpressed by various tumors including pancreatic, colorectal, glioblastomas, and prostate cancer. MDNA132 is an engineered IL-13 superkine with high specificity for IL13Rα2 and no binding to IL13Rα1 enabling targeted delivery of therapeutic immune modulators to the tumor microenvironment (TME)
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Buttner, Mark P., Patricia Cruz, Linda D. Stetzenbach, Amy K. Klima-Comba, Vanessa L. Stevens, and Peter A. Emanuel. "Evaluation of the Biological Sampling Kit (BiSKit) for Large-Area Surface Sampling." Applied and Environmental Microbiology 70, no. 12 (2004): 7040–45. http://dx.doi.org/10.1128/aem.70.12.7040-7045.2004.

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ABSTRACT Current surface sampling methods for microbial contaminants are designed to sample small areas and utilize culture analysis. The total number of microbes recovered is low because a small area is sampled, making detection of a potential pathogen more difficult. Furthermore, sampling of small areas requires a greater number of samples to be collected, which delays the reporting of results, taxes laboratory resources and staffing, and increases analysis costs. A new biological surface sampling method, the Biological Sampling Kit (BiSKit), designed to sample large areas and to be compatib
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Dalla Massara, Lorenza, Hari Prasad Osuru, Azra Oklopcic, et al. "General Anesthesia Causes Epigenetic Histone Modulation of c-Fos and Brain-derived Neurotrophic Factor, Target Genes Important for Neuronal Development in the Immature Rat Hippocampus." Anesthesiology 124, no. 6 (2016): 1311–27. http://dx.doi.org/10.1097/aln.0000000000001111.

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Abstract Background Early postnatal exposure to general anesthesia (GA) may be detrimental to brain development, resulting in long-term cognitive impairments. Older literature suggests that in utero exposure of rodents to GA causes cognitive impairments in the first-generation as well as in the second-generation offspring never exposed to GA. Thus, the authors hypothesize that transient exposure to GA during critical stages of synaptogenesis causes epigenetic changes in chromatin with deleterious effects on transcription of target genes crucial for proper synapse formation and cognitive develo
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Syaiful, Syaiful, Salma Leandra Damiana, and Muhamad Nanang Prayudyanto. "Analysis of the City Bus Service Network in Bogor City (Case Study: Bubulak Terminal - Cidangiang Route)." ASTONJADRO 13, no. 3 (2024): 643–64. https://doi.org/10.32832/astonjadro.v13i3.14963.

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BisKita Trans Pakuan Bogor Corridor 1 route line Bubulak Terminal - Cidangaing is expected to reduce the number of city transportation and private vehicles as an effort to overcome congestion in Bogor City. An assessment is needed to determine whether the service and operational performance of the bus are up to standard. The indicators used in the evaluation of operational performance refer to the Decree of the Director General of Land Transportation SK.687/AJ.206/DRJD/2002 and the world bank, while the minimum service standards refer to the Minister of Transportation Regulation No. 10 of 2012
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Rowlinson, Scott, Minh D. To, Qian Liu, Rosemina Merchant, Fahar Merchant, and Aanchal Sharma. "Abstract 7330: MDNA113: A tumor targeting and conditionally activated anti-PD1-IL2SK to enhance the therapeutic index." Cancer Research 85, no. 8_Supplement_1 (2025): 7330. https://doi.org/10.1158/1538-7445.am2025-7330.

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Abstract Background: To improve systemic tolerability of potent cytokines including anti-PD1/IL2 immunocytokines, conditional activation using tumor associated proteases have been gaining attention. MDNA113 (masked anti-PD1-IL2SK), a Bifunctional SuperKine for Immunotherapy (BiSKIT), offers key distinguishing features including (i) next-generation IL2 Superkine (IL2SK) with ‘β-enhanced not-α’ receptor selectivity, and (ii) a masking domain that also functions as a tumor targeting domain. MDNA113 incorporates an IL-13Rα2 selective IL13 superkine (IL13SK) that facilitates tumor targeting and pro
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Nurani, Yuliani, Niken Pratiwi, Robinson Situmorang, and Ni Gusti Ayu Made Yeni Lestari. "Children’s Character Learning Model Based on Indonesian Local Wisdom: Implemented to Early Childhood Education in Play Centers." JPUD - Jurnal Pendidikan Usia Dini 18, no. 1 (2024): 99–111. http://dx.doi.org/10.21009/jpud.181.07.

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Character education can equip young children to become Indonesia's golden generation who are superior and skilled in noble work. This research aims to produce an early childhood character learning model based on local Indonesian wisdom through the Playing Center title which will be implemented at Early Childhood Education Institutions (ECE) in Indonesia. This research method uses the steps of the Borg and Gall research and development model. The subjects in this research were 30 teachers from five ECE institutions in the DKI Jakarta area. The data used as the basis for building a framework for
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Mahdiyyah, Zahra, Yenny Untari Liucius, and Hokbyan R. S. Angkat Angkat. "PERSEPSI PENGGUNA LAYANAN BISKITA TRANS DEPOK TERHADAP ASPEK LAYANAN BUS DAN HALTE." JMTS: Jurnal Mitra Teknik Sipil, February 18, 2025, 313–22. https://doi.org/10.24912/jmts.v8i1.33137.

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Transportation modes are crucial for urban mobility and the quality of life of the community. BisKita Trans Depok is one of the public transportation alternatives in Depok City. This study aims to analyze the service level of BisKita Trans Depok by considering demographic and geographic factors. BisKita Trans Depok can be used by all groups with the route from Terminal Depok Baru to Harjamukti LRT Station. Respondent data were assessed for validity and reliability and then analyzed using descriptive statistical methods and cross-tabulation methods. This study examines cross-tabulations based o
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Dissertations / Theses on the topic "Methods Biskind"

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Шамрай, Д. В., та Н. А. Мельник. "Морфологические изменения в яичнике крыс на ранних сроках после операции по методике Biskind". Thesis, Издательство СумГУ, 2011. http://essuir.sumdu.edu.ua/handle/123456789/14208.

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