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Relevant bibliographies by topics / Methotrexate Testing

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Academic literature on the topic 'Methotrexate Testing'

Author: Grafiati

Published: 4 June 2021

Last updated: 19 February 2022

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Journal articles on the topic "Methotrexate Testing"

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KARWAKI, TANYA E., THOMAS K. HAZLET, and JENNIFER L. WILSON NORTON. "Lessons Learned in Developing and Testing a Methotrexate Case Study for Pharmacy Education." Cambridge Quarterly of Healthcare Ethics 29, no. 2 (March 11, 2020): 308–16. http://dx.doi.org/10.1017/s0963180119001099.

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AbstractThis article describes the development, implementation, and evaluation of a complex methotrexate ethics case used in teaching a Pharmacy Law and Ethics course. Qualitative analysis of student reflective writings provided useful insight into the students’ experience and comfort level with the final ethics case in the course. These data demonstrate a greater student appreciation of different perspectives, the potential for conflict in communicating about such cases, and the importance of patient autonomy. Faculty lessons learned are also described, facilitating adoption of this methotrex

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Chernyshov, Pavel. "Testing for HIV prior to methotrexate administration. Is it an obligatory procedure?" International Journal of Dermatology 45, no. 8 (August 2006): 998–99. http://dx.doi.org/10.1111/j.1365-4632.2006.02746.x.

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Satz, W., P. Torres, and J. W. Ufberg. "Is liver function testing necessary prior to methotrexate treatment for ectopic pregnancy?" Annals of Emergency Medicine 44, no. 4 (October 2004): S17. http://dx.doi.org/10.1016/j.annemergmed.2004.07.057.

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Jang, Ji-Hun, Seung-Hyun Jeong, and Yong-Bok Lee. "Enhanced Lymphatic Delivery of Methotrexate Using W/O/W Nanoemulsion: In Vitro Characterization and Pharmacokinetic Study." Pharmaceutics 12, no. 10 (October 16, 2020): 978. http://dx.doi.org/10.3390/pharmaceutics12100978.

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Methotrexate, which is widely used in the treatment of cancer and immune-related diseases, has limitations in use because of its low bioavailability, short half-life, and tissue toxicity. Thus, in this study, a nano-sized water-in-oil-in-water (W/O/W) double emulsion containing methotrexate was prepared to enhance its lymphatic delivery and bioavailability. Based on the results from solubility testing and a pseudo-ternary diagram study, olive oil as the oil, Labrasol as a surfactant, and ethanol as a co-surfactant, were selected as the optimal components for the nanoemulsion. The prepared nano

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Eisenberger, M., S. Krasnow, S. Ellenberg, H. Silva, J. Abrams, V. Sinibaldi, D. Van Echo, and J. Aisner. "A comparison of carboplatin plus methotrexate versus methotrexate alone in patients with recurrent and metastatic head and neck cancer." Journal of Clinical Oncology 7, no. 9 (September 1989): 1341–45. http://dx.doi.org/10.1200/jco.1989.7.9.1341.

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Patients with recurrent and metastatic squamous cell carcinoma of the head and neck (SCCHN) were stratified by performance status, extent of disease, and prior radiotherapy and subsequently randomized to receive carboplatin (CBDCA; Bristol-Myers, Wallingford, CT) administered intravenously (IV) monthly, initially at doses of 400 mg/m2 in combination with methotrexate (MTX) given IV weekly at doses of 40 mg/m2 or MTX alone at the same dose/schedule. Significant dose-limiting myelosuppression required CBDCA dose reductions to 300 mg/m2 and, subsequently, 200 mg/m2. Nonhematological toxicities we

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Gunawan, Prastiya Indra, and Darto Saharso. "A case of juvenile dermatomyositis responding to methotrexate and steroid." Bangladesh Journal of Medical Science 17, no. 4 (September 19, 2018): 675–77. http://dx.doi.org/10.3329/bjms.v17i4.38336.

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A 4-year-old patient presented with skin rash and muscle weakness. She was diagnosed with juvenile dermatomyositis based on Bohan and Peter criteria as well as laboratory testing. She received steroid and combined with methotrexate. The treatment resulted in a good response.Bangladesh Journal of Medical Science Vol.17(4) 2018 p.675-677

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Bennett, James A., Steven M. Parnes, and Ronald C. DeConti. "Growth and Chemosensitivity of Human Head and Neck Cancers Implanted under the Kidney Capsule of Cyclosporine-Immunosuppressed Mice." Annals of Otology, Rhinology & Laryngology 98, no. 6 (June 1989): 455–60. http://dx.doi.org/10.1177/000348948909800612.

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Thirty-seven of 54 human squamous cell head and neck carcinomas were grown successfully as first transplant generation xenografts under the kidney capsule of conventional mice immunosuppressed by daily treatment with 60 mg/kg of cyclosporine. Eighteen different tumors were evaluated for chemosensitivity to cis-diamminedichloroplatinum (cisplatin), 5-fluorouracil, and methotrexate. Thirty-nine percent of the tumors responded to cisplatin, 19% to 5-fluorouracil, and 33% to methotrexate. This assay response is consistent with the clinical response of human squamous head and neck carcinoma to thes

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Kavanaugh, Arthur, Ronald F. van Vollenhoven, Roy Fleischmann, Paul Emery, Iain Sainsbury, Stefan Florentinus, Su Chen, Benoît Guérette, Hartmut Kupper, and Josef S. Smolen. "Testing treat-to-target outcomes with initial methotrexate monotherapy compared with initial tumour necrosis factor inhibitor (adalimumab) plus methotrexate in early rheumatoid arthritis." Annals of the Rheumatic Diseases 77, no. 2 (November 16, 2017): 289–92. http://dx.doi.org/10.1136/annrheumdis-2017-211871.

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ObjectivesTo compare responses in patients with early rheumatoid arthritis (RA) initially treated with the tumour necrosis factor inhibitor (TNFi) adalimumab+methotrexate (MTX) versus MTX monotherapy who may have continued receiving MTX or switched to adalimumab rescue therapy after inadequate response to MTX.MethodsOPTIMA enrolled MTX-naive patients with active RA for <1 year. This post hoc analysis determined the proportion of patients, stratified by initial treatment, who achieved 28-joint modified Disease Activity Score based on C reactive protein <3.2, normal function and/or no radi

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KOCHARLA, LAKSHMI, JANALEE TAYLOR, TRACEY WEILER, TRACY V. TING, MICHAEL LUGGEN, and HERMINE I. BRUNNER. "Monitoring Methotrexate Toxicity in Juvenile Idiopathic Arthritis." Journal of Rheumatology 36, no. 12 (November 16, 2009): 2813–18. http://dx.doi.org/10.3899/jrheum.090482.

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Objective.To determine the frequency of laboratory abnormalities with methotrexate (MTX) use in patients with juvenile idiopathic arthritis (JIA); to identify potential risk factors for MTX toxicity requiring medical interventions; and to compare the frequency of liver function abnormalities in patients treated with MTX to those not treated with MTX.Methods.Results of MTX surveillance laboratory testing (SLT) available in clinical databases were reviewed for 588 children with JIA. Information on demographics, JIA features, and factors previously associated with increased frequency of SLT abnor

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Hilal, Talal, Alanna Maguire, Heidi E. Kosiorek, Lisa M. Rimsza, and Allison C. Rosenthal. "Clinical Features and Cell of Origin Subtyping Using Gene Expression Profiling in HIV-Negative Patients with Primary Central Nervous System Lymphoma." Blood 132, Supplement 1 (November 29, 2018): 2977. http://dx.doi.org/10.1182/blood-2018-99-110660.

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Abstract Objectives: Primary central nervous system lymphoma (PCNSL) is a rare aggressive B-cell lymphoma, particularly in HIV-negative individuals, that represents a clinical challenge due to its location and lack of comprehensive molecular and biologic description. Histopathologic features are that of diffuse large B-cell lymphoma with expression of pan-B-cell markers as well as cell of origin (COO) germinal center B cell (GCB) and post-germinal center B cell (non-GCB) markers. Previous studies using immunohistochemistry (IHC) suggest that the majority of PCNSL cases are non-GCB. However, ge

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Dissertations / Theses on the topic "Methotrexate Testing"

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Dodridge, M. E. (Miles Edward). "The effects of variable dose methotrexate infusion in the laboratory rat." 1987. http://web4.library.adelaide.edu.au/theses/09DM/09dmd641.pdf.

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Book chapters on the topic "Methotrexate Testing"

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Clark, Robin D., and Cynthia J. Curry. "Craniosynostoses." In Genetic Consultations in the Newborn, edited by Robin D. Clark and Cynthia J. Curry, 91–100. Oxford University Press, 2019. http://dx.doi.org/10.1093/med/9780199990993.003.0013.

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This chapter reviews background information about the incidence, risk factors, genetics, recurrence risk, and epidemiology of single suture and multiple suture craniosynostosis including isolated and syndromic varieties. The discussion on the differential diagnosis of craniosynostosis summarizes its common causes, including teratogenic agents (fluconazole, maternal thyroid disorders, methotrexate, valproic acid), chromosome anomalies, and Mendelian disorders that involve extracranial malformations. The relationship between premature closure of cranial sutures of postnatal onset and positional plagiocephaly, prematurity, and microcephaly are examined. This chapter provides recommendations for testing, evaluation and management. A clinical case presentation features an infant with Saethre–Chotzen syndrome, whose mildly affected relatives had not been diagnosed.

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