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Relevant bibliographies by topics / Methoxy Chalcones

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Academic literature on the topic 'Methoxy Chalcones'

Author: Grafiati

Published: 5 June 2025

Last updated: 1 August 2025

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Journal articles on the topic "Methoxy Chalcones"

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Olender, Dorota, Anna Pawełczyk, Anna Leśków, Katarzyna Sowa-Kasprzak, Lucjusz Zaprutko, and Dorota Diakowska. "Synthesis of bis-Chalcones Based on Green Chemistry Strategies and Their Cytotoxicity Toward Human MeWo and A375 Melanoma Cell Lines." Molecules 29, no. 21 (2024): 5171. http://dx.doi.org/10.3390/molecules29215171.

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Chalcone is an aromatic ketone that forms the central core of many important biological compounds. Chalcone derivatives show various biological activities, especially anti-inflammatory, antibacterial, antioxidant, and anticancer activities, and also inhibit melanoma cell growth. In this study, we synthesized chalcone compounds with bis-chalcone’s chemical structure under microwave (MW) and microwave–ultrasound (MW-US) conditions and compared them to chalcones produced using the classical synthesis method. All bis-chalcones were synthesized with terephthalaldehyde and an appropriate aromatic ke

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Novilla, Arina, Mustofa Mustofa, Indwiani Astuti, Jumina Jumina, and Hery Suwito. "Cytotoxic Activity of Methoxy-4’amino Chalcone Derivatives Against Leukemia Cell Lines." Molecular and Cellular Biomedical Sciences 3, no. 1 (2019): 34. http://dx.doi.org/10.21705/mcbs.v3i1.44.

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Background: Chemotherapy is a common treatment for leukemia as well as in other cancer treatment. The lack of tumor selectivity and development of multi-drug resistance by chemotherapy caused the development of new strategy in cancer treatment become a pressing need. This study was performed to evaluate the anticancer activity and selectivity of seven derivatives of chalcones against K562 and HL-60 leukemia cell lines. Materials and Methods: The cytotoxicity of chalcone’s seven derivatives (compound 1-7) was tested by using MTS (3-(4,5-dimethylthiazol-2-yl)-5-(3-carboxyme-thoxyphenyl)-2-(4-sul

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V.H., Elfi Susanti, and Mulyani S. "GREEN SYNTHESIS, CHARACTERIZATION, AND ANTIBACTERIAL ACTIVITY OF METHOXY CHALCONES." RASAYAN Journal of Chemistry 15, no. 04 (2022): 2459–65. http://dx.doi.org/10.31788/rjc.2022.1546957.

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The purpose of this research is to develop the synthesis of chalcone through a green chemical approach that has the potential as an antibacterial. Chalcone synthesis was carried out using a grinding technique through a Claisen-Schmidt condensation reaction at room temperature for 30 minutes by grinding benzaldehyde (4-bromobenzaldehyde or 4- hydroxybenzaldehyde), 4'-methoxyacetophenone, and NaOH. The reaction product was purified by recrystallization through 96% ethanol. The purity of the compound was tested by TLC. Characterization of chalcones by FT IR, 1HNMR, 13C-NMR, and GC-MS showed that

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Darwish, Mahmoud I. M., Ahmed M. Moustafa, Asmaa M. Youssef, et al. "Novel Tetrahydro-[1,2,4]triazolo[3,4-a]isoquinoline Chalcones Suppress Breast Carcinoma through Cell Cycle Arrests and Apoptosis." Molecules 28, no. 8 (2023): 3338. http://dx.doi.org/10.3390/molecules28083338.

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Chalcones are interesting anticancer drug candidates which have attracted much interest due to their unique structure and their extensive biological activity. Various functional modifications in chalcones have been reported, along with their pharmacological properties. In the current study, novel chalcone derivatives with the chemical base of tetrahydro-[1,2,4]triazolo[3,4-a]isoquinolin-3-yl)-3-arylprop-2-en-1-one were synthesized, and the structure of their molecules was confirmed through NMR spectroscopy. The antitumor activity of these newly synthesized chalcone derivatives was tested on mo

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Popova, Milena, Vassya Bankova, Stefan Spassov, et al. "New Bioactive Chalcones in Propolis from El Salvador." Zeitschrift für Naturforschung C 56, no. 7-8 (2001): 593–96. http://dx.doi.org/10.1515/znc-2001-7-819.

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2′,3′-Dihydroxy-4,4′-dimethoxychalcone (1) and 2′,3′,4-trihydroxy-4′-methoxy-chalcone, two new chalcones, were isolated from propolis from El Salvador. The compounds showed significant antibacterial ana antifunfag activity and moderate toxicity to Artemia salina nauplii

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K. Saini, K. Rajendra, S. Amit Choudhary, Yogesh C. Joshi, and P. Joshi. "Solvent Free Synthesis of Chalcones and their Antibacterial Activities." E-Journal of Chemistry 2, no. 4 (2005): 224–27. http://dx.doi.org/10.1155/2005/294094.

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The solvent free synthesis of six chalcones was carried out by grinding the piperanal and the acetophenone (unsubstituted, 4-methyl, 4-methoxy, 4-bromo, 4-nitro, 3-chloro) in the presence of solid sodium hydroxide with a mortar and pestle. In general, the chalcones were obtained in high yield and high purity. Minor quantities of Ketol and Michael addition product were easily removed by recrystallization. The result indicates a correlation between the success of the solvent-free synthesis and melting point of the chalcone. Chalcone with relatively high melting points (higher than 80°C) were obt

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Mustikasari, Kamilia, and Uripto Trisno Santoso. "The Benefits of Chalcone and Its Derivatives as Antibacterial Agents: A Review." BIO Web of Conferences 20 (2020): 03007. http://dx.doi.org/10.1051/bioconf/20202003007.

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Chalcone is a secondary metabolite compound found in plants. Chalcones contain two aryl rings, namely ring A and B which connected to the α,β unsaturated ketones. Chalcone derivatives are synthesized by various substituent groups in both rings, as well as the types of rings. These variations make chalcone and its derivatives, have interesting bioactivity, one of which is antibacterial. This review is considered the chalcone-derived compounds that have antibacterial bioactivity, including methoxy, hydroxy, prenyl, and halogen groups in ring A or B. Besides, there are two forms of these rings as

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Zhang, Jing, Xin-Ling Fu, Nan Yang, and Qiu-An Wang. "Synthesis and Cytotoxicity of Chalcones and 5-Deoxyflavonoids." Scientific World Journal 2013 (2013): 1–6. http://dx.doi.org/10.1155/2013/649485.

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Chalcones1~8and 5-deoxyflavonoids9~22were synthesized in good yields by aldol condensation, Algar-Flynn-Oyamada reaction, glycosidation, and deacetylation reaction, respectively, starting from 2-acetyl phenols substituted by methoxy or methoxymethoxy group and appropriately benzaldehydes substituted by methoxy, methoxymethoxy group, or chlorine. Among them,13and17~22are new compounds. The cytotoxicity bioassays of these chalcones and 5-deoxyflavonoids were screened using the sulforhodamine B (SRB) protein staining method, and the results showed that compounds2, 4, 5, 6, 10, 15, and19exhibited

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Mulyana, Fathoni Ega, Stephanus Satria Wira Waskitha, Deni Pranowo, Melati Khairuddean, and Tutik Dwi Wahyumingsih. "Synthesis of chalcone derivatives with methoxybenzene and pyridine moieties as potential antimalarial agents." Pharmacia 70, no. 4 (2023): 1305–13. http://dx.doi.org/10.3897/pharmacia.70.e107406.

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Malaria remains an endemic disease in tropical regions, urgently needed the search for effective antimalarial agents due to resistance against existing drugs. This study investigated the potential antimalarial activity of pyridine-based chalcone derivatives against P. falciparum 3D7 and FCR3 strains. The chalcones were synthesized through a one-pot method using various pyridine carbaldehyde, resulting in yields ranging from 53.74 to 86.37%, and all products were characterized using FTIR, GC-MS, and NMR spectroscopies. Among the six chalcones tested, chalcone A [1-(2-methoxyphenyl)-3-(pyridin-2

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Mulyana, Fathoni Ega, Stephanus Satria Wira Waskitha, Deni Pranowo, Melati Khairuddean, and Tutik Dwi Wahyumingsih. "Synthesis of chalcone derivatives with methoxybenzene and pyridine moieties as potential antimalarial agents." Pharmacia 70, no. (4) (2023): 1305–13. https://doi.org/10.3897/pharmacia.70.e107406.

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Malaria remains an endemic disease in tropical regions, urgently needed the search for effective antimalarial agents due to resistance against existing drugs. This study investigated the potential antimalarial activity of pyridine-based chalcone derivatives against <i>P. falciparum</i> 3D7 and FCR3 strains. The chalcones were synthesized through a one-pot method using various pyridine carbaldehyde, resulting in yields ranging from 53.74 to 86.37%, and all products were characterized using FTIR, GC-MS, and NMR spectroscopies. Among the six chalcones tested, chalcone A [1-(2-methoxyphenyl)-3-(py

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Dissertations / Theses on the topic "Methoxy Chalcones"

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Elston, Catherine L. "The development of a general method for the asymmetric epoxidation of electron deficient alkenes." Thesis, University of Newcastle Upon Tyne, 1996. http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.322158.

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Mouloudj, Noureddine. "Contribution à l'étude des propriétés thermodynamiques des alliages liquides selenium-tellure : relations avec les propriétés structurales." Paris 13, 1987. http://www.theses.fr/1987PA132012.

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On mesure l'activité du tellure en fonction de la température et de la concentration, à partir des mesures de F. E. M. On en déduit l'enthalpie libre de formation d'alliages se-te. On détermine également l'enthalpie molaire de mélange à 623, 673 et 733k. Influence de la coordinence sur ces propriétés thermodynamiques

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Mienie, Charmain. "Gene-specific PCR analysis of differential expression of the bean Chalcone Synthase multigene family." Thesis, 2012. http://hdl.handle.net/10210/6119.

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M.Sc.<br>A common feature of multi gene families is that their members are expressed in different ways in response to environmental and developmental signals. In the present study the expression of a CHS multi gene family in bean (Phase°lus vulgari.), was studied. using a RT-PCR technique that focuses on the 3' divergent regions of the isogenes. Tissue-specific expression in roots, stems, leaves and the flowers of Phaseolus vulgaris, as well as in callus tissue, were investigated. Patterns and levels of gene expression were investigated after treatment with different elicitors as well as light

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Book chapters on the topic "Methoxy Chalcones"

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Page, E. M., and D. A. Rice. "From Transition-Metal Halides with Chalcogens." In Inorganic Reactions and Methods. John Wiley & Sons, Inc., 2007. http://dx.doi.org/10.1002/9780470145180.ch157.

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Dorhout, P. K., and H. Steinfink. "By Reactions in Chalcogen-Hydrogen Systems." In Inorganic Reactions and Methods. John Wiley & Sons, Inc., 2007. http://dx.doi.org/10.1002/9780470145203.ch161.

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Chivers, T. "The Formation of Mixed Chalcogen Bonds Except Oxygen." In Inorganic Reactions and Methods. John Wiley & Sons, Inc., 2007. http://dx.doi.org/10.1002/9780470145197.ch51.

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Mosbo, J. A., K. Reinartz, and J. G. Verkade. "Of Organophosphorus Compounds from Phosphorus Chalconides and Phosphorus Oxyacids." In Inorganic Reactions and Methods. John Wiley & Sons, Inc., 2007. http://dx.doi.org/10.1002/9780470145197.ch86.

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Mathiasch, B. "By Reaction with Organotin Halogen, Pseudohalogen, Chalcogen and Pnictogen Compounds." In Inorganic Reactions and Methods. John Wiley & Sons, Inc., 2007. http://dx.doi.org/10.1002/9780470145234.ch49.

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Srivastava, Anchal, Rajesh Kumar Shukla, Priyanka Srivastava, Pramesh Chandra, and Nishant Kumar. "Chalcogenides: Bulk and Thin Films." In Materials Science: A Field of Diverse Industrial Applications. BENTHAM SCIENCE PUBLISHERS, 2023. http://dx.doi.org/10.2174/9789815051247123010003.

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Chalcogens are the chemical elements of group 16 of the periodic table. Oxygen is treated separately from other chalcogens; it is even excluded from the term ‘chalcogen’ altogetherdue to its very different chemical behaviour from sulfur, selenium, tellurium and polonium. The heavier chalcogens have vacant d orbitals. A chalcogenide consists of at least one chalcogen element and one electropositive element. The term chalcogenide is more commonly reserved for sulfides, selenides and tellurides rather than oxides. The interest in these materials arises particularly due to their ease of fabricatio

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Roy, Ananya, and Subrata Dolui. "A BRIEF IDEA OF METAL COMPLEXES IN MEDICINAL CHEMISTRY: CURRENT STATUS AND FUTURE PROSPECTIVE." In Futuristic Trends in Chemical Material Sciences & Nano Technology Volume 3 Book 22. Iterative International Publishers, Selfypage Developers Pvt Ltd, 2024. http://dx.doi.org/10.58532/v3becs22p2ch4.

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Recent clinical research has brought attention to the rising incidence of drug resistance to well-established treatments. Antibiotics and drug resistance in particular have posed a severe threat to human health. Metal complexes have long been important in the development of medical science. Many chemical substances employed in medicine lack an entirely organic method of action, and for activation or biotransformation, the metal salt is necessary, either directly or indirectly. Metallo medicines have long attracted the interest of researchers due to their improved theranostic action through alt

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BOHM, BRUCE A. "Chalcones and Aurones." In Methods in Plant Biochemistry. Elsevier, 1989. http://dx.doi.org/10.1016/b978-0-12-461011-8.50013-5.

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Arca, Massimiliano, Gianluca Ciancaleoni, and Anna Pintus. "Computational Methods to Study Chalcogen Bonds." In Chalcogen Chemistry: Fundamentals and Applications. The Royal Society of Chemistry, 2023. http://dx.doi.org/10.1039/bk9781839167386-00476.

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Chalcogen bonds (ChB) are acknowledged to be an influential noncovalent interaction between an electron-deficient chalcogen (donor) and a Lewis base (acceptor). While a general agreement in classifying ChB among σ-hole interactions holds, the relative contribution of covalency, electrostatic, and dispersion factors is still under debate because of the different views that different computational approaches and theoretical models put forward. A comparative analysis of the computational approaches used to describe the nature of ChB is presented along with an overview of the interacting systems i

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Aitken, R. A. "10.20 Phosphorus Analogues of Indolizines." In Knowledge Updates 2022/2. Georg Thieme Verlag KG, 2022. http://dx.doi.org/10.1055/sos-sd-110-02196.

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AbstractThis chapter is a complete revision and update of the earlier Science of Synthesis contribution from 2000 describing methods for the synthesis of phosphorus analogues of indolizines. The previous route to this rare ring system, reaction of a phosphole with dimethyl acetylenedicarboxylate, has now been joined by a metathesis-based method leading to the parent dibenzophosphindolizine and its chalcogen derivatives.

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Conference papers on the topic "Methoxy Chalcones"

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Marliyana, Soerya Dewi, Maulidan Firdaus, Muhamad Widyo Wartono, Diana Inas Utami, and Uly Wulan Apriani. "Evaluation of the Antibacterial Activity of Pinostrobin Derivative Compounds from Ethylation and Allylation Reactions." In 8th International Conference on Advanced Material for Better Future. Trans Tech Publications Ltd, 2025. https://doi.org/10.4028/p-s3ucax.

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Temu Kunci (Kaempferia pandurata Roxb.) is one of the plants from the Zingiberaceae family that contains secondary metabolites derived from flavonoids. Studies on the bioactivity of flavonoid compounds from this species have shown various biological activities such as antibacterial, antioxidant, antiviral, antitumor, antipyretic, anti-inflammatory, analgesic, and insecticidal properties. Pinostrobin (5-hydroxy-7-methoxy flavanone) (1) is the major flavonoid found in the rhizomes of this plant and has been successfully derivatized through ethylation and allylation reactions. Two compounds were

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Keta, Otilija, Vladana Petković, Neda Đorđević, Miloš Đorđević, Branka Ivković та Vladimir Dobričić. "The effects of a selected methoxy substituted chalcone in human melanoma cells irradiated with γ-rays". У 2nd International Conference on Chemo and Bioinformatics. Institute for Information Technologies, University of Kragujevac, 2023. http://dx.doi.org/10.46793/iccbi23.471k.

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Given the well-established potential of chalcones in modulating the response of cancer cells to therapeutic interventions, coupled with the growing imperative to enhance their biological attributes, the objective of this study was to synthesize a methoxy-substituted chalcone (OCH3) and assess its capacity to amplify the inhibitory effects of radiation in melanoma cells known for their resistance to radiotherapy. The A375 melanoma cells were subjected to a clinically relevant dose of 2 Gy gamma irradiation. OCH3 was employed either as a standalone treatment or in conjunction with irradiation. T

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Popusoi, Ana, Nicanor Barba, and Aurelian Gulea. "Synthesis of 1,3-Phenyl(Pyridyl)propenones with thiosemicarbazidic groups." In Scientific seminar with international participation "New frontiers in natural product chemistry". Institute of Chemistry, Republic of Moldova, 2023. http://dx.doi.org/10.19261/nfnpc.2023.ab03.

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The bibliographic study of chalcones of the type 1,3-aryl(heteryl)propen-2-one with thiosemicarbazidic 4- and 1,4-disubstituted and thisemicarbazonic groups respectively gives us the information that they have a wide spectrum of biological activity, but methods of their synthesis are less described in the literature, and they became our object of study. 4,5-Dihydro-1-H-(pyrazol-3-yl)phenylhydrazinecarbothioamides 3a and 3b were obtained according to the following scheme:Reagents and reaction conditions: i, ii) 2-Py, 25oC – 24h, 90-95oC – 3h, 77-82%; iii) DMF, CH3COOH, 70-80oC, 2-3h, 60-63%. Fi

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Lazić, Anita, Luka Matović, Jelena Lađarević, Aleksandra Mašulović, Kristina Gak Simić, and Nataša Valentić. "In vitro antioxidant activity evaluation of ferrocenyl chalcones." In 36th International Congress on process engineering. SMEITS, 2023. http://dx.doi.org/10.24094/ptk.023.207.

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Ferrocene derivatives are known as antioxidants, antiparasitic, antitumor, antiviral, antibacterial and antifungal agents. In addition to applications in medicinal chemistry and drug design, ferrocene derivatives are of exceptional importance in synthetic organic chemistry, especially in catalytic asymmetric transformations. They are also used in electrochemistry and polymer chemistry, as additives in fuels, as chemosensors in agrochemistry and biosensors of glucose and active components in molecular electronics. To design new antioxidant agents, five ferrocenyl chalcones were synthesized, and

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Silva, Wender A., Lennine R. Melo, and Júlia Galvez B. Pedreira. "Microwave Assisted Reduction of Chalcones: A Versatile Method." In 14th Brazilian Meeting on Organic Synthesis. Editora Edgard Blücher, 2013. http://dx.doi.org/10.5151/chempro-14bmos-r0352-1.

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Setyaningrum, Tifania Putri, Ester Magdalena Sitompul, Z. Zulhipri, Fera Kurniadewi, and Hanhan Dianhar. "Development of chalcone synthesis: Optimization of synthetic method." In PROCEEDINGS OF THE 9TH INTERNATIONAL SYMPOSIUM ON INNOVATIVE BIOPRODUCTION INDONESIA ON BIOTECHNOLOGY AND BIOENGINEERING 2022: Strengthening Bioeconomy through Applied Biotechnology, Bioengineering, and Biodiversity. AIP Publishing, 2023. http://dx.doi.org/10.1063/5.0175857.

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Seflini, N., P. R. Triananda, F. Kurniadewi, Zulhipri, and H. Dianhar. "Synthesis of vanillin-derived chalcone using microwave irradiation method." In PROCEEDINGS OF THE 2ND INTERNATIONAL INTERDISCIPLINARY SCIENTIFIC CONFERENCE “DIGITALIZATION AND SUSTAINABILITY FOR DEVELOPMENT MANAGEMENT: ECONOMIC, SOCIAL, AND ENVIRONMENTAL ASPECTS”. AIP Publishing, 2024. http://dx.doi.org/10.1063/5.0182837.

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Ouvaroff, A. A., I. A. Butko, and N. A. Litova. "Physico-chemical properties and ecological aspect of crystalline iron (III) orthovanadate, iron (III), copper (II) and lead (II) metavanadate." In III All-Russian Scientific Conference with International Participation "Science, technology, society: Environmental engineering for sustainable development of territories". Krasnoyarsk Science and Technology City Hall, 2022. http://dx.doi.org/10.47813/nto.3.2022.6.125-136.

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In the work, iron (III) orthovanadate, iron (III), copper (II) and lead (II) metavanadates were obtained, the ratio of the obtained substances to concentrated acids – sulfuric, hydrochloric, nitric and orthophosphoric, alkalis, aqueous solutions of chlorine, bromine and iodine, some chalcogens, aluminum and magnesium oxides was studied. Melting temperatures, densities of crystalline substances, solubility in water have been experimentally determined. IR spectroscopic analysis of compounds by the method of disturbed total internal reflection was carried out for the first time. Based on the data

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Maidur, Shivaraj R., Parutagouda Shankaragouda Patil, Krishnakanth K. N., and Venugopal Rao Soma. "Ultrafast third-order nonlinear optical properties of a novel 4-methoxy-4’-nitro chalcone by z-scan and degenerate four-wave mixing techniques." In Nonlinear Optics and its Applications 2020, edited by Anna C. Peacock, Neil G. R. Broderick, and John M. Dudley. SPIE, 2020. http://dx.doi.org/10.1117/12.2555174.

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Suzuki, Hiroo, Masaaki Misawa, Yingzhe Wang, Kenji Tsuruta, and Yasuhiko Hayashi. "Tracking Optical Properties During Atomic Substitution Process from MoSe2 to Janus MoSeS." In JSAP-Optica Joint Symposia. Optica Publishing Group, 2023. http://dx.doi.org/10.1364/jsapo.2023.20p_a602_5.

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Janus transition metal dichloride (TMDC) is a TMDC with two different chalcogenide elements on the upper and lower surfaces. This special structure is reported to break the out-of-plane symmetry of the monolayer TMDC and produce out-of-plane polarization. This is expected to lead to the development of new electronic properties, such as Rashba spin splitting and piezoelectricity. There have been several reports on the synthesis of Janus TMDCs, and in recent years, the use of chalcogen spices containing H2 plasma for atomic substitution on the surface of TMDC has attracted attention since Janus

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Reports on the topic "Methoxy Chalcones"

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Phillips, Donald, and Yoram Kapulnik. Using Flavonoids to Control in vitro Development of Vesicular Arbuscular Mycorrhizal Fungi. United States Department of Agriculture, 1995. http://dx.doi.org/10.32747/1995.7613012.bard.

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Vesicular-arbuscular mycorrhizal (VAM) fungi and other beneficial rhizosphere microorganisms, such as Rhizobium bacteria, must locate and infect a host plant before either symbiont profits. Although benefits of the VAM association for increased phosphorous uptake have been widely documented, attempts to improve the fungus and to produce agronomically useful amounts of inoculum have failed due to a lack of in vitro production methods. This project was designed to extend our prior observation that the alfalfa flavonoid quercetin promoted spore germination and hyphal growth of VAM fungi in the ab

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