Relevant bibliographies by topics / Methoxy pyrazines

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Academic literature on the topic 'Methoxy pyrazines'

Author: Grafiati
Published: 4 June 2021
Last updated: 1 February 2022

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Journal articles on the topic "Methoxy pyrazines"

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Lund, Eric D. "Determination of 2-Methoxy-3-alkylpyrazines in Carrot Products by Gas Chromatography/Nitrogen–Phosphorus Detection." Journal of AOAC INTERNATIONAL 77, no. 2 (1994): 416–20. http://dx.doi.org/10.1093/jaoac/77.2.416.

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Abstract The 2-methoxy-3-alkylpyrazines in 6 types of carrot products were determined by a stripping–selective trapping procedure followed by purge-and-trap gas chromatographic analysis with an NP detector. The aroma threshold of one of the principal pyrazines, 2-methoxy-3-sec-butylpyrazine, in a carrot medium was 0.19 ng/g. The concentrations of this compound in whole-carrot products were 0.43 (fresh), 0.291 (canned, cooked), and 0.224 ng/g (frozen). A diced, cooked, and freeze-dried product contained 0.070 ng/g. All of these products contained only this pyrazine. In contrast, a shredded, bag
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Buděšínský, Miloš, Antonín Trka, Karel Stránský, and Milan Streibl. "Heterocyclic nitrogen-containing compounds from the extract of the springtail Tetrodontophora bielanensis (WAGA)." Collection of Czechoslovak Chemical Communications 51, no. 4 (1986): 956–63. http://dx.doi.org/10.1135/cccc19860956.

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Two pyrido[2,3-b]pyrazines were isolated from the extract of the springtail Tetrodontophora bielanensis (WAGA). Their structure were determined by mass and NMR spectroscopy: 2,3-dimethoxypyrido[2,3-b]pyrazine (I) and 2-methoxy-3-isopropylpyrido[2,3-b]pyrazine (II).
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3

Barlin, GB, LP Davies, SJ Ireland, MML Ngu, and JK Zhang. "Imidazo[1,2-b]pyridazines. XII. Syntheses and Central Nervous System Activities of Some Substituted Imidazo[1,2-b]pyridazines and Related Imidazo[1,2-a]pyridines, Imidazo[1,2-a]pyrimidines and Imidazo[1,2-a]pyrazines." Australian Journal of Chemistry 45, no. 5 (1992): 877. http://dx.doi.org/10.1071/ch9920877.

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Syntheses are reported for some 6-chloro(alkoxy,alkylthio and pheny1thio)-3-benzamidomethyl-(acetamidomethyl and methoxy)-2-arylimidazo[1,2-apyridines and some corresponding imidazo- [1,2- b]pyridazines, imidazo[1,2-a[pyrimidines and imidazo[l,2-a]pyrazines. IC50 values (or percentage displacement) are reported and discussed for the displacement of [3H]diazepam from rat brain membrane by each of these compounds. The imidazo[l,2-a[pyridines were generally slightly less potent than the imidazo[l,2- b]pyridazines but considerably more potent than the corresponding imidazo[1,2-a]pyrimidines or imi
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Isbera, Mostafa, Balázs Bognár, Gergely Gulyás-Fekete, Krisztina Kish, and Tamás Kálai. "Syntheses of Pyrazine-, Quinoxaline-, and Imidazole-Fused Pyrroline Nitroxides." Synthesis 51, no. 23 (2019): 4463–72. http://dx.doi.org/10.1055/s-0039-1690678.

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A synthesis of a new diamagnetic synthon, 1-methoxy-2,2,5,5-tetramethylpyrrolidine-3,4-dione, was developed. Condensation of this compound with aliphatic or aromatic 1,2-diamines followed by deprotection yielded pyrroline nitroxide-fused pyrazines, pteridines, or quinoxalines, demonstrated on 7 examples in 15–39% overall yield over 2 or 3 steps. Reaction of the diamagnetic 1,2-diketone with an aldehyde and ammonium acetate produced a pyrrolo[3,4-d]imidazole scaffold in the Debus–Radziszewski reaction.
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Kučerová-Chlupáčová, Marta, Veronika Opletalová, Josef Jampílek, et al. "New Hydrophobicity Constants of Substituents in Pyrazine Rings Derived from RP-HPLC Study." Collection of Czechoslovak Chemical Communications 73, no. 1 (2008): 1–18. http://dx.doi.org/10.1135/cccc20080001.

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Pyrazine derivatives show a wide range of biological activities. 1-Pyrazin-2-ylethan-1-ones have served as food flavourants, and together with pyrazine-2-carbonitriles have been widely used as intermediates in the synthesis of various heterocyclic compounds. In our laboratory, substituted pyrazine-2-carbonitriles and 1-pyrazin-2-ylethan-1-ones have been used as intermediates for the preparation of potential antifungal and antimycobacterial drugs. Using established methods, a library of pyrazine derivatives was synthesized. Homolytic alkylation of commercially available pyrazine-2-carbonitrile
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Černý, Ivan, Vladimír Pouzar, Miloš Buděšínský, and Pavel Drašar. "Synthesis of Symmetrical Bis-Steroid Pyrazines Connected via D-Rings." Collection of Czechoslovak Chemical Communications 65, no. 10 (2000): 1597–608. http://dx.doi.org/10.1135/cccc20001597.

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Bis-steroid pyrazines fused through rings D of the steroid skeleton were synthesized. Methods for the preparation of the corresponding rings A fused derivatives (cephalostatin type) were checked on simple androstanes and then a symmetrical D fused analogue, 5α-androstano[16'',17''-5',6']pyrazino[2',3'-16,17]-5α-androstane-3β,3''b-diol, was prepared. Partially substituted bis-steroid pyrazines in both series were prepared and their use for the preparation of higher fused compounds was discussed. No significant cytostatic activity was found on parent bis-steroid pyrazines both A and D fused.
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Ara, Katayoun Mahdavi, Larry T. Taylor, and William M. Coleman. "Conversion of Tobacco Biomass to Flavor Components by Means of Microwave and Parr Reactors." Beiträge zur Tabakforschung International/Contributions to Tobacco Research 27, no. 6 (2017): 102–12. http://dx.doi.org/10.1515/cttr-2017-0011.

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Summary In the present work, microwave and Parr reactors were utilized for synthesis of pyrazines from plant-based biomass in the presence of ammonia and different amino acids. Using these techniques led to synthesis of a relatively wide range of pyrazines with sweet odor and chocolate-like smell. The optimum synthetic conditions to have maximum pyrazine yield for both the microwave and Parr reactions were 41 g of fructose/glucose syrup derived from cellulosic biomass, 28 mL NH4OH (30%), and 0.96 g L-threonine, 0.56 g L-valine, 0.5 g L-leucine, and 0.5 g L-isoleucine at 120 °C for 30 min. Quan
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8

Mørkved, Eva H., Nils K. Afseth, and Helge Kjøsen. "Zn(quinoline)2Cl2: an efficient reagent for synthesis of zinc azaphthalocyanines with thiomorpholine- or pyrazole substituents." Journal of Porphyrins and Phthalocyanines 10, no. 11 (2006): 1301–8. http://dx.doi.org/10.1142/s1088424606000673.

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The Zn ( quinoline )2 Cl 2 complex is found to be a convenient reagent for the direct synthesis of amino-substituted, zinc azaphthalocyanines. Octa(4-thiomorpholinyl)- and octa(1-pyrazolyl)- substituted zinc azaphthalocyanines were synthesized from pyrazines, 5,6-bis(4-thiomorpholinyl)pyrazine-2,3-dicarbonitrile and 5,6-bis(1-pyrazolyl)pyrazine-2,3-dicarbonitrile, respectively and dry Zn ( quinoline )2 Cl 2. Two zinc azaphthalocyanines, both mixtures of four constitutional isomers, were synthesized by the same method, from 6-(2-thienyl)-5-(4-thiomorpholinyl)pyrazine-2,3-dicarbonitrile and from
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9

Das, Rina, and Dinesh Kumar Mehta. "Evaluation and Docking Study of Pyrazine Containing 1, 3, 4-Oxadiazoles Clubbed with Substituted Azetidin-2-one: A New Class of Potential Antimicrobial and Antitubercular." Drug Research 71, no. 01 (2020): 26–35. http://dx.doi.org/10.1055/a-1252-2378.

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Abstract Background Tuberculosis (TB) caused by Mycobacterium tuberculosis is one of the main killers of people all over the world. The major hurdles with existing therapy are the lengthy regimen and appearance of multi drug resistant (MDR) and extensively drug resistant (XDR) strains of M.tuberculosis. Aims The present work was aimed to synthesize and determine antitubercular and antimicrobial potential of some novel 3-chloro-4-aryl-1-[4-(5-pyrazin-2-yl[1,3,4]oxadiazole-2-ylmethoxy)-phenyl]-azetidin-2-one derivatives 7(a-h) from pyrazinoic acid as precursor, which is a well-established antitu
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Wang, Shijun, Xiaorong Yuan, Hao Qian, Na Li, and Junru Wang. "Design, Synthesis, and Biological Evaluation of Two Series of Novel A-Ring Fused Steroidal Pyrazines as Potential Anticancer Agents." International Journal of Molecular Sciences 21, no. 5 (2020): 1665. http://dx.doi.org/10.3390/ijms21051665.

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Background: Increasingly, different heterocyclic systems have been introduced into the steroid nucleus to significantly enhance the antitumor activities of steroid molecules. However, in this study, few literature precedents describing the pyrazine heterocyclic-condensed modification to an A-ring of steroid monomers were found, although the pyrazine group is thought to be essential for the potent anticancer activity of clinically relevant drugs and natural steroid dimers. Methods and Results: Two series of novel A-ring fused steroidal pyrazines were designed and efficiently synthesized from co
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Dissertations / Theses on the topic "Methoxy pyrazines"

1

Lund, Cynthia M. "Investigation of New Zealand Sauvignon Blanc Wine Using Trained Sensory Panels." Thesis, University of Auckland, 2009. http://hdl.handle.net/2292/5168.

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ABSTRACT A core tool of sensory science is the use of trained descriptive panels. This research describes an investigation into the role of motivation in the performance of trained panels and the use of a trained panel to develop a better understanding of the perception of Sauvignon blanc wines. Substantial investment in time and money is directed towards ensuring trained panels perform optimally. Having selected a panel, the panel leader needs to ensure that panellists provide accurate, reliable data. Panellist motivation is also an important factor to consider. While performance psychol
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2

Alberts, P. "Development of a novel LC-MS/MS method for the detection of adulteration of South African sauvignon blanc wines with 3-alkyl-2-methoxypyrazines." Thesis, Link to the Internet, 2008. http://hdl.handle.net/10019/805.

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Book chapters on the topic "Methoxy pyrazines"

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"Pyrazine Derivatives as Green Corrosion Inhibitors." In Theory and Applications of Green Corrosion Inhibitors. Materials Research Forum LLC, 2021. http://dx.doi.org/10.21741/9781644901052-6.

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Pyrazine is a six-member heterocyclic compound containing two nitrogen atoms, located at one-fourth position. A pyrazine and its derivatives are most commonly used as a pharmaceutical, food colouring agent and as a corrosion inhibitor. It has chemistry and chemical characteristics due to nitrogen atoms present which can be obtained from both naturally and synthetically. A pyrazine and its derivatives are used effectively in corrosion media to prevent metal and metal alloy from corrosion. Chemical and electrochemical methods are commonly used as corrosion monitoring techniques, in which weight loss EIS and PDP are prominent. Their mixed type of nature has been reported in previously published works. There have also been works on the use of computation calculation in recent works, which include DFT calculation and MD Simulation are the main ones. The future research related to the pyrazine has also been highlighted.
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Ye, Z. S. "40.1.8 Product Subclass 8: Piperazines." In Knowledge Updates 2021/2. Georg Thieme Verlag KG, 2021. http://dx.doi.org/10.1055/sos-sd-140-00314.

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AbstractThe piperazine unit is widely distributed in natural products and life-saving small-molecule pharmaceuticals. It is the third most common nitrogen heterocycle occurring in pharmaceuticals approved by the U. S. Food and Drug Administration. This chapter covers strategies for the synthesis and transformations of piperazines, with both classical methods and recent developments reviewed. A major focus is on cyclization reactions such as intramolecular hydroaminations, multicomponent approaches, and routes from ethane-1,2-diamine substrates. Also discussed are approaches based on hydrogenation of (hydro)pyrazines by heterogeneous catalysis and by (asymmetric) homogeneous catalysis. Finally, a variety of transformations involving modification of a substituent on a piperazine ring are surveyed, including arylations, alkylations, and oxidations.
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Journal articles
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