Academic literature on the topic 'Methoxyquinolin'

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Journal articles on the topic "Methoxyquinolin"

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Ranjan, Khunt, Datta Neela, Bharmal Fatema, and R. Parikh A. "Synthesis and biological evaluation of 3-aryl-2-(2-chloro-7- methoxyquinolin-3-yl)-4-thiazolidinones." Journal of Indian Chemical Society Vol. 78, Jan 2001 (2001): 47–48. https://doi.org/10.5281/zenodo.5872914.

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Department of Chemistry, Saurashtra University, Rajkot-360 005, India <em>Manuscript received 30 September 1999, revised 25 July 2000, accepted 22 September 2000</em> 3-Aryl-2-(2-chloro-7-methoxyquinolin-3-yI)-4-thiazolidinones (3a-m, 4a-m) have been synthesised by the condensation of thioglycolic acid/thiolactic acid with <em>N</em>-aryl-(2-chloro-7-methoxyquinolin-3-yl) azomethine (2a-m) which in turn are prepared from arylamine and&nbsp;2-chloro-7-methoxyquinoline-3-carboxaldehyde (1). The products have been evaluated for their antibacterial and antifungal activities
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Sridhar, P., Manikandan Alagumuthu, Sivakumar Arumugam, and Sabbasani Rajasekhara Reddy. "Synthesis of quinoline acetohydrazide-hydrazone derivatives evaluated as DNA gyrase inhibitors and potent antimicrobial agents." RSC Advances 6, no. 69 (2016): 64460–68. http://dx.doi.org/10.1039/c6ra09891f.

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Roopan, S. Mohana, F. Nawaz Khan, A. Sudheer Kumar, Venkatesha R. Hathwar, and Mehmet Akkurt. "(2-Chloro-8-methoxyquinolin-3-yl)methanol monohydrate." Acta Crystallographica Section E Structure Reports Online 66, no. 7 (2010): o1542. http://dx.doi.org/10.1107/s1600536810020489.

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Okezue, Mercy, Daniel Smith, Matthias Zeller, et al. "Crystal structures of salts of bedaquiline." Acta Crystallographica Section C Structural Chemistry 76, no. 11 (2020): 1010–23. http://dx.doi.org/10.1107/s2053229620013455.

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Bedaquiline [systematic name: 1-(6-bromo-2-methoxyquinolin-3-yl)-4-(dimethylamino)-2-(naphthalen-1-yl)-1-phenylbutan-2-ol, C32H31BrN2O2] is one of two important new drugs for the treatment of drug-resistant tuberculosis (TB). It is marketed in the US as its fumarate salt {systematic name: [4-(6-bromo-2-methoxyquinolin-3-yl)-3-hydroxy-3-(naphthalen-1-yl)-4-phenylbutyl]dimethylazanium 3-carboxyprop-2-enoate, C32H32BrN2O2 +·C4H3O4 −}, and about a dozen other salts of bedaquiline have been described in patent literature, but none have so far been structurally described. In a first communication, w
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Kafka, Stanislav, Andrej Pevec, Karel Proisl, Roman Kimmel, and Janez Košmrlj. "3-Ethyl-4-hydroxy-8-methoxyquinolin-2(1H)-one." Acta Crystallographica Section E Structure Reports Online 68, no. 11 (2012): o3198. http://dx.doi.org/10.1107/s1600536812043279.

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Fan, Xiao-Na, Guo-Lun XiaHou, Zhi-Qin Huang, and Ye-Chun Ding. "1-Benzyl-3-(8-methoxyquinolin-2-ylmethyl)imidazolium hexafluoridophosphate." Acta Crystallographica Section E Structure Reports Online 63, no. 9 (2007): o3785. http://dx.doi.org/10.1107/s1600536807038767.

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Ghorab, Mostafa M., Aiten M. Soliman, Gharieb S. El-Sayyad, Maged S. Abdel-Kader, and Ahmed I. El-Batal. "Synthesis, Antimicrobial, and Antibiofilm Activities of Some Novel 7-Methoxyquinoline Derivatives Bearing Sulfonamide Moiety against Urinary Tract Infection-Causing Pathogenic Microbes." International Journal of Molecular Sciences 24, no. 10 (2023): 8933. http://dx.doi.org/10.3390/ijms24108933.

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A new series of 4-((7-methoxyquinolin-4-yl) amino)-N-(substituted) benzenesulfonamide 3(a–s) was synthesized via the reaction of 4-chloro-7-methoxyquinoline 1 with various sulfa drugs. The structural elucidation was verified based on spectroscopic data analysis. All the target compounds were screened for their antimicrobial activity against Gram-positive bacteria, Gram-negative bacteria, and unicellular fungi. The results revealed that compound 3l has the highest effect on most tested bacterial and unicellular fungal strains. The highest effect of compound 3l was observed against E. coli and C
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Hochegger, Patrick, Johanna Dolensky, Werner Seebacher, et al. "8-Amino-6-Methoxyquinoline—Tetrazole Hybrids: Impact of Linkers on Antiplasmodial Activity." Molecules 26, no. 18 (2021): 5530. http://dx.doi.org/10.3390/molecules26185530.

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A new series of compounds was prepared from 6-methoxyquinolin-8-amine or its N-(2-aminoethyl) analogue via Ugi-azide reaction. Their linkers between the quinoline and the tert-butyltetrazole moieties differ in chain length, basicity and substitution. Compounds were tested for their antiplasmodial activity against Plasmodium falciparum NF54 as well as their cytotoxicity against L-6-cells. The activity and the cytotoxicity were strongly influenced by the linker and its substitution. The most active compounds showed good activity and promising selectivity.
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Ejaz, Syeda Abida, Amna Saeed, Pervez Rashid Birmani, et al. "In-silico Investigations of quinine and quinidine as potential Inhibitors of AKR1B1 and AKR1B10: Functional and structural characterization." PLOS ONE 17, no. 10 (2022): e0271602. http://dx.doi.org/10.1371/journal.pone.0271602.

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The aberrant expression of aldo keto reductases (AKR1B1 &amp; AKR1B10) has been extensively studied in different types of cancer especially the colon cancer but a very few studies have yet been reported regarding the discovery of inhibitors for the treatment of colon cancer by targeting these isozymes. Therefore, there is a need of selective inhibitors of both targets for the eradication of colon cancer. Currently, the study is focused on the exploration of two quinolone compounds i.e., (S)-(6-Methoxyquinolin-4-yl)[(1S,2R,4S,5R)-5-vinylquinuclidin-2-yl]methanol (Quinidine) and (R)-(6-Methoxyqu
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Zhu, Yu-Lan, Zhi-Feng Zhong, Qi-Fan Yin, and Wei Liu. "3-(8-Methoxyquinolin-2-ylmethyl)-1-methyl-3H-1-imidazolium hexafluorophosphate." Acta Crystallographica Section E Structure Reports Online 63, no. 7 (2007): o3231. http://dx.doi.org/10.1107/s1600536807026955.

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Dissertations / Theses on the topic "Methoxyquinolin"

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Joaquim, Angélica Rocha. "Síntese de derivados de 8-hidroxiquinolina e avaliação da atividade antimicrobiana." reponame:Biblioteca Digital de Teses e Dissertações da UFRGS, 2018. http://hdl.handle.net/10183/181465.

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A prospecção e síntese de novos derivados de 8-hidroxiquinolina está em ascensão devido às suas diversas atividades biológicas. Neste trabalho é relatada a síntese e avaliação da atividade antimicrobiana de novos derivados contendo uma sulfonamida substituída na posição 5 da 8-hidroxiquinolina ou um grupamento aminossubstituído na posição 7 da 5-cloro-8-hidroxiquinolina ou 5-cloro-8-metoxiquinolina. Os derivados 5-sulfonamidas foram preparados por clorossulfonação seguida da reação com a amina apropriada. Os derivados 7-aminossubstituído foram sintetizados através da metilação da hidroxila da
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Chen, En-Chi, and 陳恩祺. "Novel Synthesis and Mesophase Studies of 2-(4-Alkoxybiphenyl-4’-yl)-6-methoxyquinoline." Thesis, 2012. http://ndltd.ncl.edu.tw/handle/32596126627222352304.

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碩士<br>輔仁大學<br>化學系<br>100<br>A series of quinoline-containing liquid crystalline compounds were synthesized. Preparation of these compounds was completed in a short two-step reaction. Fair to good two-step overall yields of 38~55% were obtained respectively for the liquid crystalline compounds of 2-(4-Alkoxybiphenyl-4’-yl)-6-methoxyquinoline(nOPPQOMe,n=3-8). Spectral analyses were in accord with the expected structures. Polarizing optical microscopy(POM)showed only display a nematic phase. Their thermotropic behaviors were further confirmed by differential scanning calorimetry(DSC).
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Mtshemla, Vathiswa. "Synthesis of 2,3-Diaryl-4 Methoxyquinolines via Palladium- catalyzed cross coupling reactions." Diss., 2008. http://hdl.handle.net/10500/2275.

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The main objective of this investigation was to study palladium-catalyzed coupling of 2-aryl-4-chloro-3-iodoquinolines with phenyl boronic acid in order to assess the regioselectivity of carbon-carbon bond formation at either C3 or C4. The 2-aryl-4- chloro-3-iodoquinolines were subjected to Pd(PPh3)4-catalyzed coupling reaction with phenyl boronic acid in DMF in the presence of 2M sodium carbonate (aq) to afford 2,3-diaryl-4-chloroquinolines. Reaction of 2,3-diaryl-4-chloroquinolines with sodium methoxide in MeOH-DMF mixture under reflux afforded the corresponding 2,3-diaryl-4-methoxyqu
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Chang, Chih Hao, and 張志豪. "Synthesis and mesomorphic studies of a series of 2-(4-alkylphenyl)6-methoxyquinolines." Thesis, 2007. http://ndltd.ncl.edu.tw/handle/95330077814478653845.

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Liu, Chih-Wei, and 劉致緯. "Novel Synthesis and Mesophase Studies of a series of 2-(6-Alkoxynaphthalen-2-yl)-6-Methoxyquinoline." Thesis, 2014. http://ndltd.ncl.edu.tw/handle/62768607417127149155.

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碩士<br>輔仁大學<br>化學系<br>102<br>a series of 2-(4-Alkoxybiphenyl-4’yl)-6-methoxy-quinolone(nOPPQOMe, n=3-8) were synthesized. Preparation process was completed in a short two-step process. The two-step overall yields of 55%-85% were obtained. Spectral analyses were in accordance with the expected structures. Nematic phase were observed by polarizing optical microscopy(POM). Their thermotropic behaviours were further confirmed by differential scanning calorimetry(DSC).
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Book chapters on the topic "Methoxyquinolin"

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Abbruzzetti, Stefania, and Cristiano Viappiani. "Volume Changes Associated with Solute-Solvent Reorganization Following Photoinduced Proton Transfer in Aqueous Solutions of 6-Methoxyquinoline." In Hydrogen Bonding and Transfer in the Excited State. John Wiley & Sons, Ltd, 2010. http://dx.doi.org/10.1002/9780470669143.ch34.

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"4-Methoxyquinolin-2-one." In Natural Compounds. Springer New York, 2013. http://dx.doi.org/10.1007/978-1-4614-0560-3_1179.

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Conference papers on the topic "Methoxyquinolin"

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Varma, Y. Tej, Sunita Joshi, and Debi D. Pant. "Estimation of ground and excited state dipole moments of 6-methoxyquinoline from solvatochromic effect on absorption and fluorescence spectra." In PROCEEDING OF INTERNATIONAL CONFERENCE ON RECENT TRENDS IN APPLIED PHYSICS AND MATERIAL SCIENCE: RAM 2013. AIP, 2013. http://dx.doi.org/10.1063/1.4810631.

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Lee, Young Bok, Deog Joong Kim, Gina Chun Kost, Julie Frank, Chang-Ho Ahn, and Zhi-Ren Liu. "Abstract 5507: Mechanistic study of a new 4-(3, 5-dimethoxyphenyl)-N-(7-fluoro-3-methoxyquinoxalin-2-yl)piperazine-1-carboxamide compound (RX-5902)." In Proceedings: AACR 104th Annual Meeting 2013; Apr 6-10, 2013; Washington, DC. American Association for Cancer Research, 2013. http://dx.doi.org/10.1158/1538-7445.am2013-5507.

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Remenyi, Judit, Mi Young Yang, Young Bok Lee, Deog Joong Kim, and Frances V. Fuller-Pace. "Abstract 3577: Targeting localization and function of the RNA helicase DDX5/p68 with 1-(3,5-dimethoxyphenyl)-4-[(6-fluoro-2-methoxyquinoxalin-3-yl) aminocarbonyl] piperazine (RX-5902)." In Proceedings: AACR 106th Annual Meeting 2015; April 18-22, 2015; Philadelphia, PA. American Association for Cancer Research, 2015. http://dx.doi.org/10.1158/1538-7445.am2015-3577.

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