Log in

Relevant bibliographies by topics / Methylcholanthrene

Contents

Journal articles

Academic literature on the topic 'Methylcholanthrene'

Author: Grafiati

Published: 4 June 2021

Last updated: 1 August 2024

Create a spot-on reference in APA, MLA, Chicago, Harvard, and other styles

Select a source type:

Consult the lists of relevant articles, books, theses, conference reports, and other scholarly sources on the topic 'Methylcholanthrene.'

Next to every source in the list of references, there is an 'Add to bibliography' button. Press on it, and we will generate automatically the bibliographic reference to the chosen work in the citation style you need: APA, MLA, Harvard, Chicago, Vancouver, etc.

You can also download the full text of the academic publication as pdf and read online its abstract whenever available in the metadata.

Journal articles on the topic "Methylcholanthrene"

1

Arnold, P. S., R. C. Garner, and B. Tierney. "Purification and photoaffinity labelling of a rat cytosolic binding protein specific for 3-methylcholanthrene." Biochemical Journal 242, no. 2 (1987): 375–81. http://dx.doi.org/10.1042/bj2420375.

Full text

Abstract:

Rat hepatic cytosolic proteins which sediment at 4-5 S on sucrose gradients exhibit high-affinity saturable binding for the carcinogen 3-methylcholanthrene. A rat liver protein of Stokes' radius 3 nm, Mr by sodium dodecyl sulphate/polyacrylamide-gel electrophoresis of 39,000 and with specific 3-methylcholanthrene-binding activity sedimenting at 4.5 S, has been purified 315-fold to apparent homogeneity by using affinity chromatography on a column of 1-hydroxy-3-methylcholanthrene coupled to epoxy-activated Sepharose 6B, in conjunction with two gel-filtration steps. The protein purified by this

APA, Harvard, Vancouver, ISO, and other styles

2

Jacobs, J. M., P. R. Sinclair, W. J. Bement, R. W. Lambrecht, J. F. Sinclair, and J. A. Goldstein. "Oxidation of uroporphyrinogen by methylcholanthrene-induced cytochrome P-450. Essential role of cytochrome P-450d." Biochemical Journal 258, no. 1 (1989): 247–53. http://dx.doi.org/10.1042/bj2580247.

Full text

Abstract:

We have previously shown that uroporphyrinogen is oxidized to uroporphyrin by microsomes (microsomal fractions) from 3-methylcholanthrene-pretreated chick embryo liver [Sinclair, Lambrecht & Sinclair (1987) Biochem. Biophys. Res. Commun. 146, 1324-1329]. We report here that a specific antibody to chick liver methylcholanthrene-induced cytochrome P-450 (P-450) inhibited both uroporphyrinogen oxidation and ethoxyresorufin O-de-ethylation in chick-embryo liver microsomes. 3-Methylcholanthrene-pretreatment of rats and mice markedly increased uroporphyrinogen oxidation in hepatic microsomes as

APA, Harvard, Vancouver, ISO, and other styles

3

Lambrecht, R. W., J. M. Jacobs, P. R. Sinclair, and J. F. Sinclair. "Inhibition of uroporphyrinogen decarboxylase activity. The role of cytochrome P-450-mediated uroporphyrinogen oxidation." Biochemical Journal 269, no. 2 (1990): 437–41. http://dx.doi.org/10.1042/bj2690437.

Full text

Abstract:

It was previously shown that uroporphyrinogen oxidation is catalysed by a form of cytochrome P-450 induced by 3-methylcholanthrene [Sinclair, Lambrecht & Sinclair (1987) Biochem. Biophys. Res. Commun. 146, 1324-1329]. We have now measured uroporphyrinogen oxidation and uroporphyrinogen decarboxylation simultaneously in 10,000 g supernatants from the livers of methylcholanthrene-treated mice and chick embryos incubated with an NADPH-generating system. We found that uroporphyrinogen oxidation is associated with inhibition of uroporphyrinogen decarboxylase activity. The decreased uroporphyrin

APA, Harvard, Vancouver, ISO, and other styles

4

Song, B. J., H. V. Gelboin, S. S. Park, and F. K. Friedman. "Epitope-relatedness and phenotyping of hepatic cytochromes P-450 with monoclonal antibodies." Biochemical Journal 231, no. 3 (1985): 671–76. http://dx.doi.org/10.1042/bj2310671.

Full text

Abstract:

The epitope-specific cytochrome P-450 content of animal livers was analysed by radioimmunoassay using a panel of seven monoclonal antibodies (MAbs) made to a 3-methylcholanthrene-induced rat liver cytochrome P-450. Competitive radioimmunoassays utilizing a reference radiolabelled MAb and a series of unlabelled MAbs indicated that there are at least three distinct classes of MAbs to different epitopes on cytochrome P-450. In addition, a direct radioimmunoassay employing a radiolabelled second antibody detected MAb-specific cytochromes P-450 in livers from different animals. This radioimmunoassa

APA, Harvard, Vancouver, ISO, and other styles

5

Seidel, S. L., and T. K. Shires. "Purification and characterization of a previously unreported form of cytochrome P-448 from the liver of 3-methylcholanthrene-pretreated rats." Biochemical Journal 235, no. 3 (1986): 859–68. http://dx.doi.org/10.1042/bj2350859.

Full text

Abstract:

At least four hepatic isoenzymes of cytochrome P-450 were purified and characterized from rats treated with 3-methylcholanthrene. A monoclonal antibody developed against one of the forms (designated cytochrome P-450 MC-B) and polyclonal antibodies against others were used to demonstrate that form MC-B is immunologically distinct from other methylcholanthrene-inducible forms. Limited N-terminal amino acid sequencing showed that cytochrome P-450 MC-B has a primary structure that differs from the N-terminal sequences of other established rat isoenzymes. Cytochrome P-450 MC-B has a minimum Mr of 5

APA, Harvard, Vancouver, ISO, and other styles

6

Sinclair, P., J. Frezza, J. Sinclair, et al. "Immunochemical detection of different isoenzymes of cytochrome P-450 induced in chick hepatocyte cultures." Biochemical Journal 258, no. 1 (1989): 237–45. http://dx.doi.org/10.1042/bj2580237.

Full text

Abstract:

This study investigated whether the same cytochrome P-450 (P-450) isoenzymes were inducible in cultures of chick-embryo hepatocytes as in the liver of chicken embryos. We purified two isoenzymes of cytochrome P-450 from the livers of 17-day-old-chick embryos: one of molecular mass approx. 50 kDa induced in vivo by the phenobarbital-like inducer glutethimide, and the second of approx. 57 kDa induced by 3-methylcholanthrene. Rabbit antiserum against the 50 kDa protein inhibited benzphetamine demethylase activity in hepatic microsomes (microsomal fractions) from glutethimide-treated chick embryo.

APA, Harvard, Vancouver, ISO, and other styles

7

Lutz, Charles T., Garvan Browne, and C. Rosemarie Petzold. "Methylcholanthrene causes increased thymocyte apoptosis." Toxicology 128, no. 2 (1998): 151–67. http://dx.doi.org/10.1016/s0300-483x(98)00043-2.

Full text

APA, Harvard, Vancouver, ISO, and other styles

8

Harvey, Ronald G., and Cecilia Cortez. "Synthesis of cholanthrene and 6-methylcholanthrene, biologically active analogs of the potent carcinogen 3-methylcholanthrene." Journal of Organic Chemistry 52, no. 2 (1987): 283–84. http://dx.doi.org/10.1021/jo00378a025.

Full text

APA, Harvard, Vancouver, ISO, and other styles

9

Laizé, Vincent, Paulo J. Gavaia, Marco Tarasco, et al. "Osteotoxicity of 3-methylcholanthrene in fish." Ecotoxicology and Environmental Safety 161 (October 2018): 721–28. http://dx.doi.org/10.1016/j.ecoenv.2018.06.035.

Full text

APA, Harvard, Vancouver, ISO, and other styles

10

Sheen, Yhun Y., Sun S. Kim, and Hea C. Yun. "Effect of 3-methylcholanthrene on rat uterus: Uterine growth and mechanism of action of 3-methylcholanthrene." Archives of Pharmacal Research 16, no. 4 (1993): 276–82. http://dx.doi.org/10.1007/bf02977516.

Full text

APA, Harvard, Vancouver, ISO, and other styles

More sources

We offer discounts on all premium plans for authors whose works are included in thematic literature selections. Contact us to get a unique promo code!