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1

&NA;. "Methylergometrine." Reactions Weekly &NA;, no. 1379 (2011): 26. http://dx.doi.org/10.2165/00128415-201113790-00096.

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&NA;. "Methylergometrine." Reactions Weekly &NA;, no. 721 (1998): 10. http://dx.doi.org/10.2165/00128415-199807210-00033.

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&NA;. "Methylergometrine." Reactions Weekly &NA;, no. 1154 (2007): 18. http://dx.doi.org/10.2165/00128415-200711540-00060.

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&NA;. "Methylergometrine." Reactions Weekly &NA;, no. 1365 (2011): 31. http://dx.doi.org/10.2165/00128415-201113650-00112.

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&NA;. "Methylergometrine." Reactions Weekly &NA;, no. 578 (1995): 9. http://dx.doi.org/10.2165/00128415-199505780-00031.

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&NA;. "Methylergometrine." Reactions Weekly &NA;, no. 434 (1993): 11. http://dx.doi.org/10.2165/00128415-199304340-00054.

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&NA;. "Methylergometrine." Reactions Weekly &NA;, no. 621 (1996): 8. http://dx.doi.org/10.2165/00128415-199606210-00029.

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&NA;. "Methylergometrine." Reactions Weekly &NA;, no. 375 (1991): 10. http://dx.doi.org/10.2165/00128415-199103750-00058.

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&NA;. "Methylergometrine." Reactions Weekly &NA;, no. 1083 (2006): 18. http://dx.doi.org/10.2165/00128415-200610830-00054.

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&NA;. "Methylergometrine." Reactions Weekly &NA;, no. 1260 (2009): 22–23. http://dx.doi.org/10.2165/00128415-200912600-00072.

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&NA;. "Methylergometrine." Reactions Weekly &NA;, no. 1245 (2009): 26. http://dx.doi.org/10.2165/00128415-200912450-00081.

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&NA;. "Methylergometrine." Reactions Weekly &NA;, no. 349 (1991): 10. http://dx.doi.org/10.2165/00128415-199103490-00041.

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&NA;. "Methylergometrine." Reactions Weekly &NA;, no. 364 (1991): 9. http://dx.doi.org/10.2165/00128415-199103640-00040.

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&NA;. "Methylergometrine." Reactions Weekly &NA;, no. 1289 (2010): 29–30. http://dx.doi.org/10.2165/00128415-201012890-00088.

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&NA;. "Methylergometrine." Reactions Weekly &NA;, no. 1302 (2010): 34. http://dx.doi.org/10.2165/00128415-201013020-00105.

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&NA;. "Methylergometrine." Reactions Weekly &NA;, no. 1008 (2004): 15. http://dx.doi.org/10.2165/00128415-200410080-00047.

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&NA;. "Methylergometrine." Reactions Weekly &NA;, no. 499 (1994): 10. http://dx.doi.org/10.2165/00128415-199404990-00044.

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&NA;. "Methylergometrine." Reactions Weekly &NA;, no. 512 (1994): 10. http://dx.doi.org/10.2165/00128415-199405120-00049.

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&NA;. "Methylergometrine." Reactions Weekly &NA;, no. 531 (1994): 10. http://dx.doi.org/10.2165/00128415-199405310-00034.

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20

&NA;. "Methylergometrine/oxytocin." Reactions Weekly &NA;, no. 1377 (2011): 25. http://dx.doi.org/10.2165/00128415-201113770-00081.

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&NA;. "Methylergometrine/ritodrine." Reactions Weekly &NA;, no. 1196 (2008): 30. http://dx.doi.org/10.2165/00128415-200811960-00090.

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&NA;. "Methylergometrine/oxytocin." Reactions Weekly &NA;, no. 1339 (2011): 29. http://dx.doi.org/10.2165/00128415-201113390-00090.

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23

&NA;. "Methylergometrine/ergotamine/methysergide." Reactions Weekly &NA;, no. 402 (1992): 13. http://dx.doi.org/10.2165/00128415-199204020-00057.

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24

M., El-Raey, and Rasha E. Azab. "AUGMENTING CERVIMETRY, FETAL SURVIVABILITY, CALVING EASE, AND UTERINE HEALTH DURING BUFFALO UTERINE TORSION TREATMENT." International Journal of Advanced Research 10, no. 08 (2022): 1095–106. http://dx.doi.org/10.21474/ijar01/15275.

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A total of 52 buffalo cows suffering from uterine torsion were divided into seven groups.Each animal in the groupwas subjected to diagnosis depending upon clinical signs, rectal, vaginal, and ultrasonographic examination then subjected to one of the formulatedtherapeutic regimes.Cervimetry, state of fetal livability, parturition easiness, placental dropping time, and uterine health witheach specific treatment were recorded. Results: groups injected with denaverine hydrochloride, denaverine hydrochloride potentiated with methylergometrine showed rapid cervical dilation rate (3.1±0.26cm and 3
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25

Alam, Anjuman, Paresh Shyam, and Swapnil Goswami. "A comparative study of efficacy of oxytocin, methylergometrine and misoprostol in prevention of post-partum haemorrhage." International Journal of Reproduction, Contraception, Obstetrics and Gynecology 6, no. 5 (2017): 1960. http://dx.doi.org/10.18203/2320-1770.ijrcog20171957.

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Background: To compare the efficacy of oxytocin, methylergometrine and misoprostol in active management of third stage of labour (AMTSL).Methods: A clinical study was conducted on 330 low risk pregnant women with a healthy singleton pregnancy and spontaneous onset of labour at term; allocated into three groups where active management of third stage of labour was done with either Oxytocin 10 IU intramuscular, or Methylergometrine 0.2 mg intramuscular, or tab Misoprostol 600µg sublingual on 110 women each group. Primary parameter was blood loss during labour. Secondary parameters were the durati
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26

Gadappa, Shrinivas N., Deepika Sharma, and Yogita Gavit. "Comparative study of various oxytocics in management of third stage of labour." International Journal of Reproduction, Contraception, Obstetrics and Gynecology 7, no. 10 (2018): 4035. http://dx.doi.org/10.18203/2320-1770.ijrcog20184125.

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Background: Causes of maternal mortality are haemorrhages, infections, unsafe abortions, and obstructed labour. 25% of these are caused by haemorrhages and are preventable, one of the measures is active management of third stage of labour (AMTSL). For prevention, treatment of postpartum haemorrhage oxytocics are available oxytocin, methylergometrine, misoprostol, prostaglandin F2α.Methods: Study was conducted, 160 patients were randomly given one of following oxytocics a) tablet misoprostol 600 µg per rectal b) Inj. Oxytocin 10 IU IM c) Inj. Methylergometrine 0.2 mg IM d) Inj. PGF2α. Duration
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27

Votava, Z., and I. Podvalová. "Pharmacological Studies of Ergometrine and Methylergometrine." Acta Pharmacologica et Toxicologica 13, no. 3 (2009): 309–18. http://dx.doi.org/10.1111/j.1600-0773.1957.tb00267.x.

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28

van Gelder, T. "Misoprostol versus methylergometrine: farmacokinetiek in moedermelk." MFM 43, no. 4 (2005): 102. http://dx.doi.org/10.1007/bf03058583.

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29

Müller-Schweinitzer, Else, and Carlo Tapparelli. "Methylergometrine, an Active Metabolite of Methysergide." Cephalalgia 6, no. 1 (1986): 35–41. http://dx.doi.org/10.1046/j.1468-2982.1986.0601035.x.

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In conscious dogs methysergide (MS) caused constriction of the saphenous vein at about 3000 times lower doses than methylergometrine (MT) when infused locally, but it elicited only a short-lasting venoconstrictor response when injected systemically intravenously. MS and MT proved to be equally active venoconstrictor agents when administered orally. Analysis of canine plasma by high-performance liquid chromatography showed that after both oral and intravenous administration of MS large amounts of MT appeared in the plasma whereas only low and transient levels of MS could be detected. It is sugg
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30

Carlisa, Belinda. "Comparison of carbetocin with other uterotonic agents in preventing postpartum hemorrhage." International Journal of Reproduction, Contraception, Obstetrics and Gynecology 7, no. 12 (2018): 5207. http://dx.doi.org/10.18203/2320-1770.ijrcog20184997.

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Postpartum hemorrhage (PPH) is defined as blood loss of at least 500 ml or more after vaginal delivery and 1000 ml or more after abdominal delivery. It contributes up to 28% of maternal mortality worldwide and 30.3% of maternal death in Indonesia. 70% cases of PPH are caused by uterine atony. PPH can be prevented by doing routine use of uterotonic agents in active management of third stage of labour. Uterotonic agents that currently available are oxytocin, carbetocin, methylergometrine, syntometrine, misoprostol and carboprost. Carbetocin (a long-acting synthetic analogue of oxytocin) is a new
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31

Meneghetti, Fiorella, Patrizia Ferraboschi, Paride Grisenti, Shahrzad Reza Elahi, Matteo Mori, and Samuele Ciceri. "Crystallographic and NMR Investigation of Ergometrine and Methylergometrine, Two Alkaloids from Claviceps Purpurea." Molecules 25, no. 2 (2020): 331. http://dx.doi.org/10.3390/molecules25020331.

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Ergometrine and methylergometrine are two alkaloids that are used as maleate salts for the prevention and control of postpartum hemorrhage. Although the two molecules have been known for a long time, few and discordant crystallographic and NMR spectroscopic data are available in the literature. With the aim of providing more conclusive data, we performed a careful NMR study for the complete assignment of the 1H, 13C, and 15N NMR signals of ergometrine, methylergometrine, and their maleate salts. This information allowed for a better definition of their conformational equilibria. In addition, t
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32

Srinivasan, Sabitha Umapathy, and Swarnamukhi P. "Role of methylergometrine versus oxytocin in the active management of third stage of labour: a randomised control trial." International Journal of Reproduction, Contraception, Obstetrics and Gynecology 10, no. 10 (2021): 3732. http://dx.doi.org/10.18203/2320-1770.ijrcog20213683.

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Background: Postpartum haemorrhage (PPH) is the leading cause of maternal death globally. The routine practice of active management of third stage of labour has been shown to reduce haemorrhage by up to 60%. The present study evaluated the role of methylergometrine versus oxytocin in active management of third stage of labour in reducing the risk of PPH.Methods: This study was conducted on a total of 400 women admitted in the labour ward of PESIMSR hospital, by using simple randomized design. The first study group included women who received intramuscular oxytocin (n=200) and, the second group
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33

Koehler, PJ, and PC Tfelt-Hansen. "History of Methysergide in Migraine." Cephalalgia 28, no. 11 (2008): 1126–35. http://dx.doi.org/10.1111/j.1468-2982.2008.01648.x.

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Harold Wolff's theory of vasodilation in migraine is well-known. Less known is his search for a perivascular factor that would damage local tissues and increase pain sensitivity during migraine attacks. Serotonin was found to be among the candidate agents to be included. In the same period, serotonin was isolated (1948) and, because of its actions, an anti-serotonin drug was needed. Methysergide was synthesized from lysergic acid (LSD) by adding a methyl group and a butanolamid group. This resulted in a compound with selectivity and high potency as a serotonin (5-HT) inhibitor. Based on the po
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34

Bhute, Sindhu, Deepti Shrivastava, Deepali Khamsara та Poonam Pandey. "Sublingual 400 μg Misoprostol vs Intravenous 0.2 mg Methylergometrine for Active Management of Third Stage of Labor". Journal of South Asian Federation of Obstetrics and Gynaecology 5, № 1 (2013): 15–18. http://dx.doi.org/10.5005/jp-journals-10006-1211.

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ABSTRACT Objectives To compare the efficacy and side effects of sublingual 400 μg misoprostol with 0.2 mg intravenous methylergometrine in active management of third stage of labor. Materials and methods In a prospective, randomized comparative study conduted in Department of Obstetrics and Gynecology, AVBRH, Wardha, 200 women at full-term gestation, without any high risk factors were studied in two groups of 100 each, for safety and efficacy of 400 μg sublingual misoprostol in comparison to 0.2 mg intravenous methylergometrine at the delivery of anterior shoulder from December 2010 to Novembe
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35

Meena, Banwari Lal. "Use of Oral Misoprostol, Intramuscular Oxytocin and Intravenous Methergin in Prevention of Postpartum Haemorrhage." Nepal Journal of Obstetrics and Gynaecology 8, no. 1 (2013): 34–36. http://dx.doi.org/10.3126/njog.v8i1.8859.

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Aims: The purpose of the study was to compare the efficacy of misoporstol 600mg orally (Group A), injection oxytocin 10 IU intramuscularly (Group B) and injection methylergometrine 0.2 mg intravenously (Group C) on reducing blood loss in third stage of labour, duration of third stage of labour, effect on haemoglobin of the patient, need of additional oxytocics or blood transfusion and associated side effects and complications. Methods: A prospective study enrolling 510 women and randomising them into three groups was done in S P Medical College, Bikaner, Rajasthan, India. Active management of
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36

&NA;. "Oral methylergometrine after caesarean section reduces endometritis." Inpharma Weekly &NA;, no. 731 (1990): 12. http://dx.doi.org/10.2165/00128413-199007310-00027.

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37

Rohlíček, Jan, Michal Hušák, Bohumil Kratochvíl, and Alexandr Jegorov. "Methylergometrine maleate from synchrotron powder diffraction data." Acta Crystallographica Section E Structure Reports Online 65, no. 12 (2009): o3252—o3253. http://dx.doi.org/10.1107/s1600536809050351.

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38

Vogel, Danièle, Tilo Burkhardt, Katharina Rentsch, et al. "Misoprostol versus methylergometrine: Pharmacokinetics in human milk." American Journal of Obstetrics and Gynecology 191, no. 6 (2004): 2168–73. http://dx.doi.org/10.1016/j.ajog.2004.05.008.

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39

Aeby, Alec, Anne-Britt Johansson, Bruno De Schuiteneer, and Denise Blum. "Methylergometrine Poisoning in Children: Review of 34 Cases." Journal of Toxicology: Clinical Toxicology 41, no. 3 (2003): 249–53. http://dx.doi.org/10.1081/clt-120021107.

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40

Tfelt-Hansen, P., I. Jansen, and L. Edvinsson. "Methylergometrine antagonizes 5 HT in the temporal artery." European Journal of Clinical Pharmacology 33, no. 1 (1987): 77–79. http://dx.doi.org/10.1007/bf00610384.

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41

Enweronu-Laryea, CC, I. Aryee, A. Frimpong-Barfi, and OP Rodrigues. "Methylergometrine Poisoning In The Newborn: Report Of Two Cases." East African Medical Journal 85, no. 9 (2008): 463. http://dx.doi.org/10.4314/eamj.v85i9.9663.

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42

Mäntylä, R., T. Kleimola, and J. Kanto. "Pharmacokinetics of Methylergometrine (Methylergonovine) in the Rabbit and Man." Acta Pharmacologica et Toxicologica 40, no. 5 (2009): 561–69. http://dx.doi.org/10.1111/j.1600-0773.1977.tb02111.x.

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43

Mäntylä, R., T. Kleimola, and J. Kanto. "Pharmacokinetics of Methylergometrine (Methylergonovine) in the Rabbit and Man." Acta Pharmacologica et Toxicologica 40 (March 13, 2009): 561–69. http://dx.doi.org/10.1111/j.1600-0773.1977.tb03558.x.

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44

Spaulding, Christian, Simon Weber, Francois Guerin, and Philippe D'Hallivillee. "Coronary artery spasm triggered by oral administration of methylergometrine." Lancet 338, no. 8762 (1991): 317. http://dx.doi.org/10.1016/0140-6736(91)90458-2.

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45

Bredberg, U., G. S. Eyjolfsdottir, L. Paalzow, P. Tfelt-Hansen, and V. Tfelt-Hansen. "Pharmacokinetics of methysergide and its metabolite methylergometrine in man." European Journal of Clinical Pharmacology 30, no. 1 (1986): 75–77. http://dx.doi.org/10.1007/bf00614199.

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46

Bhoi, Dhiren B., Naresh F. Chaudhari, Jitendra K. Raval, and Gaurav M. Pandya. "Effect of Different Ecbolic Agents on Postpartum Reproductive Performance in Surti Buffaloes." Indian Journal of Veterinary Sciences & Biotechnology 18, no. 4 (2022): 133–35. http://dx.doi.org/10.48165/ijvsbt.18.4.27.

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The study was conducted to evaluate the effect of different ecbolic therapies on puerperium in twenty four Surti buffaloes divided into four different groups consisting of six animals in each. Buffaloes in Group-I (T1) were not given any treatment and considered as control group. Group-II (T2) and Group- III (T3) buffaloes were injected methylergometrine (5 mg) and dinoprost tromethamine (25 mg) i/m, respectively, immediately after parturition. The animals in Group-IV (T4) received oral herbal ecbolic, 100 mL, daily for first 10 days postpartum. The time required for placental expulsion, persi
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47

Akita, Mitsuhiro, Takefumi Oka, Toshiyuki Takamura, Akio Kajiyama, Teruo Shiraki, and Daiji Saitou. "Acute myocardial infarction produced by methylergometrine malcate-induced coronary vasospasam." Nihon Naika Gakkai Zasshi 93, no. 7 (2004): 1442–44. http://dx.doi.org/10.2169/naika.93.1442.

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48

Bredberg, U., and L. Paalzow. "Pharmacokinetics of methysergide and its metabolite methylergometrine in the rat." Drug Metabolism and Disposition 18, no. 3 (1990): 338–43. https://doi.org/10.1016/s0090-9556(25)08495-8.

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49

Tfelt-Hansen, P., U. Bredberg, G. S. Eyjolfsdottir, L. Paalzow, and V. Tfelt-Hansen. "Kinetics of Methysergide and its Main Metabolite, Methylergometrine, in Man." Cephalalgia 5, no. 3_suppl (1985): 54–55. http://dx.doi.org/10.1177/03331024850050s314.

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50

Mäntylä, R., J. Kanto, T. Kleimola, and M. Seppälä. "Plasma and Tissue Concentrations of Methylergometrine (Methylergonovine) in the Rabbit." Acta Pharmacologica et Toxicologica 46, no. 4 (2009): 245–49. http://dx.doi.org/10.1111/j.1600-0773.1980.tb02449.x.

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