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Journal articles on the topic 'Methylquinoline'

Author: Grafiati

Published: 5 June 2025

Last updated: 1 August 2025

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1

Greenhill, John V., Hossein Loghmani-Khouzani, and Derek J. Maitland. "Tautomerism in ketomethyl quinolines. Part 3. 4-Ketomethylquinolines." Canadian Journal of Chemistry 69, no. 4 (1991): 696–701. http://dx.doi.org/10.1139/v91-104.

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A series of 4-ketomethylquinolines has been prepared and their tautomerism investigated. The compounds were prepared from 4-methylquinoline deprotonated with lithium diisopropylamide or potassium ethoxide and treated with esters. Attempted deprotonation with tert-butyllithium or phenyllithium led to 2-substituted-4-methylquinolines. The simple alkyl or aryl 4-keto methylquinolines exist essentially as the keto forms, but the quinoline-4-pyruvates are exclusively or substantially in the enol forms. Key words: ketomethyl quinolines, pyruvates, tautomerism, enols.

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2

Basavaraju, B., H. S. Bhojya Naik, and M. C. Prabhakara. "Synthesis, Characterization and Antimicrobial Activity of Methylquinolino[3,2-b][1,5]benzodiazepine and Methylquinolino[3,2-b][1,5]benzoxazepine and its Various Metal Complexes." E-Journal of Chemistry 4, no. 1 (2007): 32–38. http://dx.doi.org/10.1155/2007/639828.

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2-Chloro-6-methylquinoline-3-carbaldehyde was condensed witho-Phenylenediammine and 2-aminophenol in presence of potassium iodide. The resulting Methylquinolino[3,2-b][1,5]benzodiazepine (MQBD) and Methylquinolino[3,2-b][1,5]benzoxazepine(MQBO) were characterized by elemental analysis and spectral studies. The metal chelatesvizPd(II), Rh(III) and Ru(III) of ligands were prepared and characterized by metal-ligand (M:L) ratio, UV-Visible, IR,1H NMR spectroscopes and magnetic properties. The antibacterial and antifungal activity of MQBD, MQBO and its metal complexes were screened against various

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3

Ismail, Mostafa. "Synthesis and cyclization reactions of 2-(6-methylquinolin-4-yl)malononitriles and ethyl 2-cyano-2-(6-methylquinolin-4-yl)acetates." Journal of the Serbian Chemical Society 71, no. 7 (2006): 721–32. http://dx.doi.org/10.2298/jsc0607721i.

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The nucleophilic substitution reactions of 2,4-dichloro-6-methylquinoline (1) and 4-chloro-6-methylquinolin-2(1H)-one (7) with malononitrile and ethyl cyanoacetate are described. The quinolinylmalononitrile 8a and cyanoacetate 8b were utilized to prepare the novel polyfunctionalized benzoquinolinones 10a,b, pyridylquinolinones 11a,b, pyrazolylquinolinones 12a-e isoxazolylquinolinone 13, pyrimidylquinolinones 14a-c, thienoquinolinones 15, 16a,b, and pyridothienoquinolinones 17a,b. The structures of the new compounds were based on analytical and spectral results.

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4

Kudikala, Sadanandam, Pinnoju Prasad, S. K. Manasa, and Sarasija Madderla. "Synthesis and Anticancer Activity of New 2-methylquinoline with Pyridine, Thiazole and Pyrazole Derivatives." Research Journal of Chemistry and Environment 28, no. 12 (2024): 31–41. https://doi.org/10.25303/2812rjce031041.

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This work presents a novel class of 2-methylquinoline derivatives that combine pyridine, thiazole, pyrazole ring systems. The precursor 1-(2-methylquinolin-3-yl) ethanone (1) is combined with aldehydes, malononitrile and ethyl cyanoacetate in a one-pot synthesis to produce 2-amino-6-(2-methylquinolin-3-yl)-4-phenylpyridine hybrids 2 and 3. Synthetic approaches to the (E)-1-(1-(2-methylquinolin-3-yl) ethylidene) hybrids 5, 6, to treat 1 with thiosemicarbazide and 1-chloropropan-2-one and to get 7, 8, the compound 1 is treated with bromine and thiourea. Then by using 2-chloroacetyl chloride and

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5

Chirico, R. D., and W. V. Steele. "Thermodynamic Properties of 2-Methylquinoline and 8-Methylquinoline." Journal of Chemical & Engineering Data 50, no. 2 (2005): 697–708. http://dx.doi.org/10.1021/je049595u.

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6

N., D. SHARMA, KUMAR SANTOSH, V. BAKORE P., and C. JOSHI B. "Condensation of 2-Anilino-4-methylquinoline Derivatives with Substituted-diethylmalonate and Studies of Isomerism through Nmr Spectra." Journal of Indian Chemical Society Vol. 64, Aug 1987 (1987): 481–82. https://doi.org/10.5281/zenodo.6199354.

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Department of Chemistry, University of Rajasthan, Jaipur-302 004 <em>Manuscript received 6 February 1979, accepted 22 January 1987</em> 2 [<em>N</em>-(2,2-Dicarbethoxyvinyl)anilino]-4-methyl-quinoline (6), 2-[<em>N</em>-(2,2-dicarbethoxyvinyl)-2-chloroanilino]-4-methylquinoline (7) and 2-N-(2,2-dicarbethoxyvinyl)-4- methylquinoline (8) were prepared by condensing ethoxymethylene diethyl malonate (4) with 2-anilino-4-methyl-quinoline (1), 2-(2-chlorosailino)-4-methylquinoline (2) and 2.(4-methoxyanilino)-4-methyl quinoline (3), respectively. 2-[<em>N</em>-(2-Carbethoxy-2- pbenacetyl)anilin

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7

Soliman, Fouad, Ibrahim Abd-Ellah, Soher Maigali, and Gamal Abd-El-Naim. "Chemistry of Phosphorus Ylides. Part 27. Metal Complexes of 4-hydroxyquinaldine, its Mannich Base and Phosphonium Ylide." Journal of Chemical Research 2009, no. 5 (2009): 277–82. http://dx.doi.org/10.3184/030823409x440841.

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The reaction of Hg2+,Cd2+,Co2+, and Ni2+ ions with 1 mol of the ligands 2-methylquinoline-4-ol,3[(diethylamino)methyl]-2-methylquinoline-4-ol, and methyl-3-(4-hyrdoxy-2-methylquinoline-3-yl)-2-(triphenylphosphoranylidene)propanoate, has been investigated to give the corresponding 1:1 metal:ligand complexes. Reaction of 2 mol of the ligand gave the corresponding 1:2 metal:ligand complexes. The coordination takes place only through the quinoline nitrogen atom. The spectroscopic and the physicochemical data of the new metal complexes are discussed.

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8

Rahim, Abdul, Siddiq Pasha Shaik, Mirza Feroz Baig, Abdullah Alarifi, and Ahmed Kamal. "Iodine mediated oxidative cross-coupling of unprotected anilines and heteroarylation of benzothiazoles with 2-methylquinoline." Organic & Biomolecular Chemistry 16, no. 4 (2018): 635–44. http://dx.doi.org/10.1039/c7ob02241g.

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Iodine mediated dual C–H activation of Csp<sup>3</sup>–H of 2-methylquinoline and Csp<sup>2</sup>–H of anilines for the construction of C–C and C–O bonds and the oxidative insertion of 2-methylquinoline to the benzothiazole under metal and peroxide free condition.

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9

Kulkarni, Mukund G., Mayur P. Desai, Deekshaputra R. Birhade, Yunus B. Shaikh, Ajit N. Dhatrak, and Ramesh Gannimani. "A Wittig-olefination–Claisen-rearrangement approach to the 3-methylquinoline-4-carbaldehyde synthesis." Beilstein Journal of Organic Chemistry 8 (October 11, 2012): 1725–29. http://dx.doi.org/10.3762/bjoc.8.197.

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Efficient syntheses are described for the synthetically important 3-methylquinoline-4-carbaldehydes 6a–h from o-nitrobenzaldehydes 1a–h employing a Wittig-olefination–Claisen-rearrangement protocol. The Wittig reaction of o-nitrobenzaldehydes with crotyloxymethylene triphenylphosphorane afforded crotyl vinyl ethers 2a–h, which on heating under reflux in xylene underwent Claisen rearrangement to give 4-pentenals 3a–h. Protection of the aldehyde group of the 4-pentenals as acetals 4a–h and subsequent oxidative cleavage of the terminal olefin furnished nitroaldehydes 5a–h. Reductive cyclization o

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10

Lynch, Daniel E., and Ian McClenaghan. "2-Chloro-4-methylquinoline." Acta Crystallographica Section E Structure Reports Online 57, no. 1 (2000): o54—o55. http://dx.doi.org/10.1107/s1600536800019590.

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The structure of the title compound, C10H8ClN, comprises planar molecules that form stacked columns parallel to thebcell direction. Two symmetry-related molecules associateviaC—H...N interactions to form a non-planarR22(8) dimer.

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11

Wang, Yi-Zhen. "8-Methoxy-2-methylquinoline." Acta Crystallographica Section E Structure Reports Online 63, no. 7 (2007): o3230. http://dx.doi.org/10.1107/s1600536807027614.

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12

Fazaeli, Yousef, Mostafa M. Amini, Shan Gao, and Seik Weng Ng. "8-Hydroxy-2-methylquinoline." Acta Crystallographica Section E Structure Reports Online 64, no. 1 (2007): o97. http://dx.doi.org/10.1107/s1600536807063246.

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13

Wu, Tian-Quan, Jian-Hua Wang, Fang Shen, and Ai-Xi Hu. "8-Chloro-2-methylquinoline." Acta Crystallographica Section E Structure Reports Online 65, no. 7 (2009): o1463. http://dx.doi.org/10.1107/s1600536809020194.

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14

Yang, Lin-Tao, Fang Shen, Jiao Ye, Tian-Quan Wu, and Ai-Xi Hu. "8-Bromo-2-methylquinoline." Acta Crystallographica Section E Structure Reports Online 65, no. 7 (2009): o1490. http://dx.doi.org/10.1107/s1600536809020625.

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15

Aldoghachi, Raghad Jawad Kadhim, Faris Abdulridha Jassim Aldoghachi, Tahseen Abdul Qader Alsalim, and Mohd Lokman Ibrahim. "Synthesis, Thermal Analysis, and Thermodynamic Properties Study of New Quinoline Derivative and Their V(IV), Co(II), and Cu(II) Complexes." Indonesian Journal of Chemistry 22, no. 5 (2022): 1376. http://dx.doi.org/10.22146/ijc.74423.

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A new ligand (E)-2-((2-chloro-6-methylquinoline-3-yl)methylene)-N'-((E)-(2-chloro-6-methylquinoline-3-yl)methylene)hydrazine-1-carbothiohydrazide (QH) was prepared by reacting hydrazine hydrate with carbon disulfide to yield thiocarbohydrazide. The thiocarbohydrazide in the second step was treated with a quinoline derivative 2-chloro-6-methylquinoline-3-carbaldehyde to yield the ligand. The ligand was identified by spectroscopic techniques FTIR, 1H-NMR, and 13C-NMR. Next, vanadium (V), cobalt (Co), and copper (Cu) complexes were prepared in the [M:L] ratio of 1:1 (QV, QCo, QCu). The complexes

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16

UEMASU, Isamu, and Yukio NAGAO. "Separation of 2-Methylquinoline from 8-Methylquinoline through Inclusion Complexation with .ALPHA.-Cyclodextrin." Journal of The Japan Petroleum Institute 34, no. 5 (1991): 469–72. http://dx.doi.org/10.1627/jpi1958.34.469.

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17

Gotoh, Kazuma, and Hiroyuki Ishida. "Crystal structures of four isomeric hydrogen-bonded co-crystals of 6-methylquinoline with 2-chloro-4-nitrobenzoic acid, 2-chloro-5-nitrobenzoic acid, 3-chloro-2-nitrobenzoic acid and 4-chloro-2-nitrobenzoic acid." Acta Crystallographica Section E Crystallographic Communications 76, no. 11 (2020): 1701–7. http://dx.doi.org/10.1107/s2056989020013134.

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The structures of the four isomeric compounds of 6-methylquinoline with chloro- and nitro-substituted benzoic acids, C7H4ClNO4·C10H9N, namely, 2-chloro-4-nitrobenzoic acid–6-methylquinoline (1/1), (I), 2-chloro-5-nitrobenzoic acid–6-methylquinoline (1/1), (II), 3-chloro-2-nitrobenzoic acid–6-methylquinoline (1/1), (III), and 4-chloro-2-nitrobenzoic acid–6-methylquinoline (1/1), (IV), have been determined at 185–190 K. In each compound, the acid and base molecules are linked by a short hydrogen bond between a carboxyl O atom and an N atom of the base. The O...N distances are 2.5452 (12), 2.6569

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18

Rodríguez, Diego, Sergio Andrés Guerrero, Alirio Palma, Justo Cobo, and Christopher Glidewell. "4-Styrylquinolines from cyclocondensation reactions between (2-aminophenyl)chalcones and 1,3-diketones: crystal structures and regiochemistry." Acta Crystallographica Section C Structural Chemistry 76, no. 9 (2020): 883–90. http://dx.doi.org/10.1107/s2053229620010803.

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Structures are reported for two matched sets of substituted 4-styrylquinolines which were prepared by the formation of the heterocyclic ring in cyclocondensation reactions between 1-(2-aminophenyl)-3-arylprop-2-en-1-ones with 1,3-dicarbonyl compounds. (E)-3-Acetyl-4-[2-(4-methoxyphenyl)ethenyl]-2-methylquinoline, C21H19NO2, (I), (E)-3-acetyl-4-[2-(4-bromophenyl)ethenyl]-2-methylquinoline, C20H16BrNO, (II), and (E)-3-acetyl-2-methyl-4-{2-[4-(trifluoromethyl)phenyl]ethenyl}quinoline, C21H16F3NO, (III), are isomorphous and in each structure the molecules are linked by a single C—H...O hydrogen bo

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19

Tai, Xi-Shi, Jun Xu, Yi-Min Feng, and Zu-Pei Liang. "4-Amino-2-methylquinoline monohydrate." Acta Crystallographica Section E Structure Reports Online 64, no. 6 (2008): o1026. http://dx.doi.org/10.1107/s1600536808013093.

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20

Grigoryan, Karine R., Hasmik A. Shilajyan, Iskuhi L. Aleksanyan, Zara L. Grigoryan, and Lilit P. Hambardzumyan. "THE EFFECT OF DIMETHYLSULFOXIDE ON THE FLUORESCENCE PROPERTIES OF SOME 4-HYDROXYQUINOLINES." Proceedings of the YSU B: Chemical and Biological Sciences 55, no. 2 (255) (2021): 112–17. http://dx.doi.org/10.46991/pysu:b/2021.55.2.112.

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Fluorescence properties of 4-hydroxy-2-methylquinoline (1) and 2-(5-mercapto-1,3,4-oxadiazol-2-yl)-6-methylquinoline-4-ol (2) were studied in dimethylsulfoxide (DMSO) aqueous solutions. The fluorescence properties of 1 and 2 exhibit substantial dependence on the DMSO concentration. The fluorescence quantum yield $(\Phi_f)$ of 1 decreases upon adding DMSO due to the shift in the keto-enol (E) tautomeric equilibrium toward E form․ On the contrary 2 demonstrates a tendency of increase of $\Phi_f$ upon adding DMSO due to intermolecular charge transfer from DMSO to the aromatic ring of quinoline, w

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21

Aznar, E., B. Ruiz, and C. Gutiérrez Losa. "Excess molar enthalpies at 298.15 K of (cyclohexane + a methylquinoline) and of (benzene + a methylquinoline)." Journal of Chemical Thermodynamics 17, no. 12 (1985): 1121–26. http://dx.doi.org/10.1016/0021-9614(85)90038-2.

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22

Sonawane, Ratnamala P., and Rahul R. Tripathi. "The Chemistry and Synthesis of 1H-indole-2,3-dione (Isatin) and its Derivatives." International Letters of Chemistry, Physics and Astronomy 12 (September 2013): 30–36. http://dx.doi.org/10.18052/www.scipress.com/ilcpa.12.30.

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Isatins are synthetically versatile substrates, where they can be used for the synthesis of a large variety of heterocyclic compounds. In this, a convenient method has been developed for the conversion of Indoles into Isatins and some heterocyclic derivative were synthesised such as 5- nitro-1H-indole-2,3-dione, 2-methylquinoline-4-carboxylic acid which may be used as raw material for drug synthesis. The general process utilizes the effective method for synthesis of Isatin from Indole is bromination and oxidation with an N-bromosuccinimide-dimethyl sulfoxide reagent. The nitration of Isatin at

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23

Pfaller, Stacy L., Susan D. Sutton, and Brian K. Kinkle. "Sphingomonassp. strain Lep1: an aerobic degrader of 4-methylquinoline." Canadian Journal of Microbiology 45, no. 7 (1999): 623–26. http://dx.doi.org/10.1139/w99-046.

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Strain Lep1, isolated from a bacterial consortium capable of aerobic degradation of 4-methylquinoline (4-MQ), was chosen for further characterization as it was the only member of the consortium able to grow on 4-MQ in pure culture. Lep1 was identified as a Sphingomonas sp. based on phylogenetic analysis of 16S rDNA. Furthermore, the presence of sphingolipids and 2-hydroxy fatty acids in the membrane, and a 63% G + C ratio supports the placement of Lep1 in this genus. Additional genetic, physiological, and ecological characterization of bacteria such as Lep1 will allow for the potential exploit

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24

Sonawane, Ratnamala P., and Rahul R. Tripathi. "The Chemistry and Synthesis of 1H-indole-2,3-dione (Isatin) and its Derivatives." International Letters of Chemistry, Physics and Astronomy 12 (April 20, 2013): 30–36. http://dx.doi.org/10.56431/p-8lif75.

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Isatins are synthetically versatile substrates, where they can be used for the synthesis of a large variety of heterocyclic compounds. In this, a convenient method has been developed for the conversion of Indoles into Isatins and some heterocyclic derivative were synthesised such as 5- nitro-1H-indole-2,3-dione, 2-methylquinoline-4-carboxylic acid which may be used as raw material for drug synthesis. The general process utilizes the effective method for synthesis of Isatin from Indole is bromination and oxidation with an N-bromosuccinimide-dimethyl sulfoxide reagent. The nitration of Isatin at

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25

Natarajan, S., K. Rajesh, V. Vijayakumar, J. Suresh, and P. L. Nilantha Lakshman. "4-Azido-2-chloro-6-methylquinoline." Acta Crystallographica Section E Structure Reports Online 65, no. 4 (2009): o671. http://dx.doi.org/10.1107/s1600536809007041.

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26

Khan, F. Nawaz, R. Subashini, S. Mohana Roopan, Venkatesha R. Hathwar, and Seik Weng Ng. "2-Chloro-6-methylquinoline-3-carbaldehyde." Acta Crystallographica Section E Structure Reports Online 65, no. 11 (2009): o2686. http://dx.doi.org/10.1107/s1600536809040653.

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27

Subashini, R., F. Nawaz Khan, Rajesh Kumar, Venkatesha R. Hathwar, and Seik Weng Ng. "2-Chloro-7-methylquinoline-3-carbaldehyde." Acta Crystallographica Section E Structure Reports Online 65, no. 11 (2009): o2721. http://dx.doi.org/10.1107/s1600536809040823.

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28

Khan, F. Nawaz, R. Subashini, Atul Kumar Kushwaha, Venkatesha R. Hathwar, and Seik Weng Ng. "2-Chloro-8-methylquinoline-3-carbaldehyde." Acta Crystallographica Section E Structure Reports Online 65, no. 11 (2009): o2722. http://dx.doi.org/10.1107/s1600536809040859.

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29

Diadié, Camara Hadietou, Attar Khalid, Boutayeb Mohammed, Benchidmi Mohamed, and Essassi El Mokhtar. "3-Ethoxycarbonyl-1,4-dihydro-2-methylquinoline." Molecules 6, no. 12 (2001): M243. http://dx.doi.org/10.3390/m243.

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30

Wang, Dahan, Feng Zhang, Fuhong Xiao, and Guo-Jun Deng. "A three-component approach to isoxazolines and isoxazoles under metal-free conditions." Organic & Biomolecular Chemistry 17, no. 41 (2019): 9163–68. http://dx.doi.org/10.1039/c9ob01909j.

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A 1,3-dipolar cycloaddition of 2-methylquinoline, tert-butyl nitrite (TBN) and alkynes or alkenes for the synthesis of biheteroaryls containing both isoxazoline/isoxazole and quinoline motifs has been developed.

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31

Thamaraiselvi, S., and P. S. Mohan. "An Approach to the Synthesis of New 1-Phenylacridones and Naphthacridones." Zeitschrift für Naturforschung B 54, no. 10 (1999): 1337–41. http://dx.doi.org/10.1515/znb-1999-1018.

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A short synthesis of 1-phenylacridones, Napth[2,1-a]acridones and Napth[2,3-a]acridones is described, starting from 4-hydroxy-2-methylquinoline by condensing it with respective aldehydes followed by oxidative photolytic cyclization.

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32

Liu, Li-jun, Qing-jie Luan, Jing Lu, et al. "8-Hydroxy-2-methylquinoline-modified H4SiW12O40: a reusable heterogeneous catalyst for acetal/ketal formation." RSC Advances 8, no. 46 (2018): 26180–87. http://dx.doi.org/10.1039/c8ra04471f.

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A heteropoly acid based organic hybrid heterogeneous catalyst, HMQ-STW, was prepared by combining 8-hydroxy-2-methylquinoline (HMQ) with Keggin-structured H<sub>4</sub>SiW<sub>12</sub>O<sub>40</sub> (STW).

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33

EBINA, Takeo, Chiaki YOKOYAMA, and Shinji TAKAHASHI. "Solid-liquid Equilibria for the Quinoline-indole, Isoquinoline-indole, 2-Methylquinoline-indole and 2-Methylquinoline-isoquinoline Systems." Journal of The Japan Petroleum Institute 38, no. 6 (1995): 413–20. http://dx.doi.org/10.1627/jpi1958.38.413.

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34

Tilborg, Anaelle. "Crystal structure of 2,2′-oxybis(4-methylquinoline)." Acta Crystallographica Section E Crystallographic Communications 71, no. 2 (2015): 180–83. http://dx.doi.org/10.1107/s2056989015000717.

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The title compound, C20H16N2O, (I), has been unwittingly obtained from the slow evaporation of a saturated solution of commercial benserazide hydrochloride [benserazide, (II), being one of the principal therapeutic compounds used for the management of Parkinson's disease, mostly used in combination with levodopa]. The molecule of (I) is composed of two planar 4-methylquinoline aromatic moieties [maximum deviations of 0.0104 (18) and 0.016 (2) Å], almost perpendicular to each other [dihedral angle = 89.5 (2)°], bridged by an O atom. The supramolecular organization consists of a π-bonded chain,

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35

Lee, So Jeong, Allen F. Brooks, Naoko Ichiishi, et al. "C–H 18F-fluorination of 8-methylquinolines with Ag[18F]F." Chemical Communications 55, no. 20 (2019): 2976–79. http://dx.doi.org/10.1039/c9cc00641a.

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This report describes a Pd-mediated C–H radiofluorination of 8-methylquinoline derivatives with no-carrier-added Ag[<sup>18</sup>F]F. Fluorination of 10 examples in up to 21% RCY and high molar activity is reported, as well as automation of the process in a radiochemistry synthesis module.

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36

Landge, Vinod G., Manoj K. Sahoo, Siba P. Midya, Garima Jaiswal, and Ekambaram Balaraman. "Well-defined palladium(ii) complexes for ligand-enabled C(sp3)-alkynylation." Dalton Transactions 44, no. 35 (2015): 15382–86. http://dx.doi.org/10.1039/c5dt02772a.

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The first example of ligand-enabled C(sp<sup>3</sup>)-alkynylation of 8-methylquinoline is reported. The reaction is catalysed by well-defined Pd(ii) complexes. The present C(sp<sup>3</sup>)-alkynylation has a broad substrate scope as well as functional group tolerance and proceeds under mild conditions.

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37

Qiu, Dengxu, Chenhui Jiang, Pan Gao, and Yu Yuan. "Lewis acid-promoted direct synthesis of isoxazole derivatives." Beilstein Journal of Organic Chemistry 19 (October 16, 2023): 1562–67. http://dx.doi.org/10.3762/bjoc.19.113.

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Isoxazole derivatives were synthesized via a one-pot method utilizing 2-methylquinoline derivatives as template substrates, sodium nitrite as a nitrogen-oxygen source, and solely using aluminum trichloride as the additive. This approach circumvents the need for costly or highly toxic transition metals and presents a novel pathway for the synthesis of isoxazole derivatives.

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38

Choi, Han Young, Dong Wook Kim, Dae Yoon Chi, Eun Young Yoon, and Dong Jin Kim. "Preparation of 7-Alkylamino-2-methylquinoline-5,8-diones." Journal of Organic Chemistry 68, no. 11 (2003): 4608. http://dx.doi.org/10.1021/jo039927i.

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39

Yu, Seung Man, Chi-Ho Park, Pan-Gi Kim, Cheal Kim та Youngmee Kim. "Tetra-μ-benzoato-bis[(6-methylquinoline)copper(II)]". Acta Crystallographica Section E Structure Reports Online 64, № 7 (2008): m881—m882. http://dx.doi.org/10.1107/s1600536808016516.

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40

Benzerka, Saida, Abdelmalek Bouraiou, Sofiane Bouacida, Thierry Roisnel, and Ali Belfaitah. "2-Bromoethyl 2-chloro-6-methylquinoline-3-carboxylate." Acta Crystallographica Section E Structure Reports Online 66, no. 4 (2010): o1006. http://dx.doi.org/10.1107/s1600536810010160.

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41

Zeletchonok, Yu B., V. V. Zorin, M. C. Klyavlin, et al. "Homolytic substitution of 2-methylquinoline by crown ethers." Tetrahedron Letters 29, no. 39 (1988): 5037–38. http://dx.doi.org/10.1016/s0040-4039(00)80673-5.

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42

Márquez, F., I. Zabala, and F. Tomás. "Photophysical behavior of 3-methylquinoline and 3-bromoquinoline." Journal of Luminescence 54, no. 1 (1992): 13–22. http://dx.doi.org/10.1016/0022-2313(92)90044-a.

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43

Choi, Han Young, Dong Wook Kim, Dae Yoon Chi, Eun Young Yoon, and Dong Jin Kim. "Preparation of 7-Alkylamino-2-methylquinoline-5,8-diones†." Journal of Organic Chemistry 67, no. 15 (2002): 5390–93. http://dx.doi.org/10.1021/jo0257039.

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44

Ravikumar Naik, Tangali, Halehatty Bhojya Naik, S. Ramesh, M. Raghavendra, and G. Krishnamurthy. "One-pot Synthesis of 2-seleno-4-methylquinoline." Molbank 2007, no. 3 (2007): M543. http://dx.doi.org/10.3390/m543.

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45

Aleksanyan, I. L., and L. P. Hambardzumyan. "Reactions of 2-chloro-4-methylquinolines with sulfur nucleophiles and of 4-methylquinoline-2(1H)-thiones with substituted benzyl chlorides." Russian Journal of Organic Chemistry 50, no. 3 (2014): 442–44. http://dx.doi.org/10.1134/s1070428014030257.

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46

Naik, Tangali R. Ravikumar, Halehatty S. Bhojya Naik, Halehatty R. Prakasha Naik, and P. J. Bindu. "Three-Component One-Pot Synthesis of Novel Benzo[b]1,8-naphthyridines Catalyzed by Bismuth(III) Chloride." Research Letters in Organic Chemistry 2008 (December 28, 2008): 1–4. http://dx.doi.org/10.1155/2008/594826.

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Abstract:

A novel and efficient three-component one-pot synthesis of benzo[b]1,8-naphthyridines by 2-amino-4-methylquinoline, aromatic aldehydes, and malononitrile was done. The reaction was catalyzed by an acidic Bismuth(III) chloride, functionalized Bismuth(III) chloride, at room temperature to give various benzo[b]1,8-naphthyridines in high yields. The Bismuth(III) chloride is an environmentally friendly catalyst.

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47

Rajnák, Cyril, Ľubor Dlháň, Ján Moncol, Ján Titiš та Roman Boča. "Slow magnetic relaxation in a μ1,1′-azido cobalt(ii) methylquinoline chain complex". Dalton Transactions 47, № 44 (2018): 15745–50. http://dx.doi.org/10.1039/c8dt03351j.

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A [Co(N<sub>3</sub>)<sub>2</sub>(mqu)] complex with a 1D chain architecture (mqu – 4-methylquinoline) shows slow magnetic relaxation with three distinct modes. The relaxation time strongly depends upon the applied external field. The low-frequency mode exhibits a relaxation time longer than one second: τ<sub>LF</sub> = 1.6(2) s at B<sub>DC</sub> = 0.8 T and T = 1.9 K.

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48

Liu, Sheng, Lian Duan, Ming-Xing Zuo та ін. "Palladium-Catalyzed Cascade Synthesis of Novel Quinolone- Bis(indolyl)methane Hybrids as Promising α-Glucosidase Inhibitors". Synthesis 52, № 11 (2020): 1680–86. http://dx.doi.org/10.1055/s-0039-1690871.

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An unexpected cascade reaction is developed for the construction of functionalized 3-bis(indol-3-yl)methylquinoline-2(1H)-ones. Three C–C bonds and one ring are created in one pot triggered by Pd-catalyzed C-3 alkenylation of indole with 2-acyl-N-acrylaniline derivatives. A series of complex and specific quinoline-2(1H)-ones were produced, most of them showed significant α-glucosidase inhibitory activities.

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An, Heishoku, Ryosyo Ishizawa, Kojiro Sato, Satoji Kobayashi, and Ryutoku Yosomiya. "Junction properties of ClO4−-doped poly(methylquinoline) with indium." Synthetic Metals 58, no. 3 (1993): 335–41. http://dx.doi.org/10.1016/0379-6779(93)91142-o.

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50

Zelechonok, Yu B., V. V. Zorin, S. S. Zlotskii, and D. L. Rakhmankulov. "Homolytic alkylation of 2-methylquinoline with 18-crown-6." Chemistry of Heterocyclic Compounds 21, no. 9 (1985): 1056. http://dx.doi.org/10.1007/bf00515034.

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