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Dissertations / Theses on the topic 'Microbial toxins'

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1

McKenzie, Jenna Elyse Sheff David R. "The recycling endosome is required for transport of retrograde toxins." [Iowa City, Iowa] : University of Iowa, 2009. http://ir.uiowa.edu/etd/406.

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檀東煇 and T. F. Tan. "Elucidation of ganglioside binding domain in the B-subunit of cholera toxin." Thesis, The University of Hong Kong (Pokfulam, Hong Kong), 2000. http://hub.hku.hk/bib/B31223448.

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3

Tan, T. F. "Elucidation of ganglioside binding domain in the B-subunit of cholera toxin." Hong Kong : University of Hong Kong, 2000. http://sunzi.lib.hku.hk/hkuto/record.jsp?B23636634.

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4

Scanferlato, Vjera Sostarec. "Environment risk assessment for toxic chemicals and genetically-engineered microorganisms : a microcosm approach /." Diss., This resource online, 1990. http://scholar.lib.vt.edu/theses/available/etd-07282008-135357/.

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5

Tsang, J. S. H. "The physiology and genetics of bacterial dehalogenases." Thesis, University of Kent, 1987. http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.380588.

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6

McKay, A. C. "Investigations to develop methods to control the nematode associated with annual ryegrass toxicity /." Title page, contents and summary only, 1985. http://web4.library.adelaide.edu.au/theses/09PH/09phm153.pdf.

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7

Linares, Katherine Anne. "Evaluating strategies for integrating bacterial cells into a biosensor designed to detect electrophilic toxins." Thesis, Virginia Tech, 2004. http://hdl.handle.net/10919/10113.

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To improve the process stability of wastewater treatment plants, the construction of a whole-cell bacterial biosensor is explored to harness the natural stress response of the bacterial cells. The stress response selected in this work is the glutathione-gated potassium efflux (GGKE) system, which responds to electrophilic stress by effluxing potassium from the interior to the exterior of the cell. Thus, the bulk potassium in solution can be monitored as an indicator of bacterial stress. By utilizing this stress response in a biosensor, the efflux of potassium can be correlated to the stress re
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8

Misson, Benjamin Olivier. "Potentiel toxique et structure génétique de populations de Microcystis en lien avec les différentes phases de son cycle de vie." Thesis, Clermont-Ferrand 2, 2011. http://www.theses.fr/2011CLF22168/document.

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L‟eutrophisation croissante des écosystèmes aquatiques favorise le développement des cyanobactéries, parmi lesquelles Microcystis est la plus représentée dans les régions tempérées. La capacité de Microcystis à produire une puissante hépatotoxine, la microcystine, est à l‟origine de diverses perturbations écologiques, et de nombreuses nuisances sanitaires. La compréhension des facteurs déterminant la toxicité des efflorescences de Microcystis constitue, de fait, un enjeu majeur des recherches actuelles. Dans ce contexte, l‟objectif premier de ce travail de thèse était d‟étudier la variabilité
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9

Vacchini, V. F. "MICROBIAL ECOLOGY OF THE SPOTTED WING FLY DROSOPHILA SUZUKII." Doctoral thesis, Università degli Studi di Milano, 2014. http://hdl.handle.net/2434/247234.

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Abstract Symbiotic relationships between arthropods and microorganisms are widespread in nature. In the last years these interactions are received considerable attention, as many microorganisms may play relevant roles in the biology and lifecycle of insects (Dale and Moran, 2006; Moran et al., 2008). In this perspective, researchers are directing many efforts to depict the interactions that shape the symbiosis. Furthermore, considering the importance that microorganisms play for their hosts, the modification of the microbiome structure in the insect body could support the development of sus
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10

Stiles, Bradley G. "Purification and characterization of Clostridium perfringens iota toxin." Diss., Virginia Polytechnic Institute and State University, 1987. http://hdl.handle.net/10919/76516.

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Clostridium perfringens type E iota toxin is implicated in some cases of fatal diarrhea in calves, lambs, and guinea pigs. A crossreacting "iota-like" toxin, produced by Clostridium spiroforme, is responsible for antibiotic-associated and weaning related enterotoxemias of rabbits. Antisera developed against culture supernatant of either organism neutralized the biological activity of iota or iota-like toxin. By using C. spiroforme antiserum and crossed immunoelectrophoresis (crossed IEP), we found two cross-reacting antigens in C. perfringens type E supernatants. C. perfringens types A, B, C,
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11

Barberis, Luis Rodrigo Miyamoto [UNESP]. "Metodologia para determinação de efeitos fisiológicos e metabólicos do glufosinate em soja." Universidade Estadual Paulista (UNESP), 2012. http://hdl.handle.net/11449/99972.

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Made available in DSpace on 2014-06-11T19:30:25Z (GMT). No. of bitstreams: 0 Previous issue date: 2012-05-16Bitstream added on 2014-06-13T19:00:30Z : No. of bitstreams: 1 barberis_lrm_dr_botfca.pdf: 840865 bytes, checksum: 2158433b6e8b218bb15ad11592a60db9 (MD5)<br>Coordenação de Aperfeiçoamento de Pessoal de Nível Superior (CAPES)<br>O glufosinate é derivado do fosfinotricina, uma toxina microbiana natural isolada a partir de duas espécies de fungos Streptomyces. Atua inibindo a atividade da enzima glutamina sintetase, que é necessária para a produção do aminoácido glutamina e para a desinto
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12

Barberis, Luis Rodrigo Miyamoto 1975. "Metodologia para determinação de efeitos fisiológicos e metabólicos do glufosinate em soja /." Botucatu : [s.n.], 2012. http://hdl.handle.net/11449/99972.

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Orientador: Caio Antonio Carbonari<br>Coorientador: Edivaldo Domingues Velini<br>Banca: Fernando Tadeu de Carvalho<br>Banca: Marcus Barifouse Matallo<br>Banca: Cleber Daniel de Goes Maciel<br>Banca: Elza Alves Corrêa<br>Resumo: O glufosinate é derivado do fosfinotricina, uma toxina microbiana natural isolada a partir de duas espécies de fungos Streptomyces. Atua inibindo a atividade da enzima glutamina sintetase, que é necessária para a produção do aminoácido glutamina e para a desintoxicação da amônia pela planta. Objetivou-se neste trabalho avaliar a intoxicação e alterações fisiológicas e b
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13

Novoselov, Alexey [Verfasser], Wilhelm [Gutachter] Boland, Erika [Gutachter] Kothe, and Aleksandr V. [Gutachter] Oleskin. "Einfluss pflanzlicher Toxine auf das Mikrobiom von Spodoptera littoralisImpact of plant toxins on the gut microbial community of Spodoptera littoralis / Alexey Lvovich Novoselov ; Gutachter: Wilhelm Boland, Erika Kothe, Aleksandr V. Oleskin." Jena : Friedrich-Schiller-Universität Jena, 2018. http://d-nb.info/1170398863/34.

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14

Silva, Ilca Puertas de Freitas e. [UNESP]. "Velocidade de absorção do glufosinate e seus efeitos em plantas daninhas e algodão." Universidade Estadual Paulista (UNESP), 2012. http://hdl.handle.net/11449/86406.

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Made available in DSpace on 2014-06-11T19:22:16Z (GMT). No. of bitstreams: 0 Previous issue date: 2012-12-04Bitstream added on 2014-06-13T19:27:10Z : No. of bitstreams: 1 silva_ipf_me_botfca.pdf: 811263 bytes, checksum: f5d3077013320ac555e0dc1689b1cc81 (MD5)<br>Coordenação de Aperfeiçoamento de Pessoal de Nível Superior (CAPES)<br>O glufosinate é um herbicida derivado do fosfinotricina, uma toxina microbiana natural isolada a partir de duas espécies de fungos do gênero Streptomyces. O mecanismo de ação é a inibição direta da enzima glutamina sintetase, que resulta no aumento da concentração
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Silva, Ilca Puertas de Freitas e. 1986. "Velocidade de absorção do glufosinate e seus efeitos em plantas daninhas e algodão /." Botucatu : [s.n.], 2012. http://hdl.handle.net/11449/86406.

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Orientador: Caio Antonio Carbonari<br>Coorientador: Edivaldo Domingues Velini<br>Banca: Fernando Tadeu de Carvalho<br>Banca: Ana Catarina Cataneo<br>Resumo: O glufosinate é um herbicida derivado do fosfinotricina, uma toxina microbiana natural isolada a partir de duas espécies de fungos do gênero Streptomyces. O mecanismo de ação é a inibição direta da enzima glutamina sintetase, que resulta no aumento da concentração de amônio, sendo tóxico para as células. A pesquisa teve como objetivo avaliar a velocidade de absorção do glufosinate e seus efeitos em plantas daninhas e na cultura do algodão.
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16

Mogotsi, Lerato Bonolo. "An assessment of the lipopolysaccharide toxicity of rough and smooth escherichia coli strains cultivated in the presence of zygosaccharomyces bailli." Thesis, Bloemfontein : Central University of Technology, Free State, 2011. http://hdl.handle.net/11462/151.

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Thesis (M. Tech. Environmental health) -- Central University of technology, Free State, 2011<br>In nature microorganisms do not exist alone, but in association with one another. These kinds of associations can also be found in food industries, where cells of the same or different species can attach to pipes (biofilm formation) and a variety of surfaces in food processing environments and in food product such as yoghurt which can contain both yeast and bacteria originating from the starter culture as well as fruit. To control food spoilage organisms and food-borne pathogens preventative measur
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17

Smith, Elvina Melinda. "Influence of extrinsic stresses on growth and endotoxin profiles of escherichia coli and pseudomonas aeruginosa." Thesis, Bloemfontein : Central University of Technology, Free State, 2011. http://hdl.handle.net/11462/152.

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Thesis (M. Tech. Environmental health) -- Central University of technology, Free State, 2011<br>The threat to the world food supply and the concern for public health as a result of food-borne diseases has been established as a constant global problem. The safety of food, in particular, is of significance to consumers and producers alike. Regarding the diseases related to food-borne pathogens, the disease syndromes affecting the entire human body has become inestimable. The focus of the study was to establish the effect of sanitisers, detergents and household storage temperatures on the growth
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18

Promdonkoy, Boonhiang. "Molecular biology of a microbial toxin." Thesis, University of Cambridge, 2000. http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.621541.

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19

Rodrigues, Susana Gonçalves. "Microbial warfare: the role of valinomycin and cereulide." Master's thesis, Universidade de Aveiro, 2009. http://hdl.handle.net/10773/4555.

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Mestrado em Microbiologia<br>As estirpes eméticas de Bacillus cereus produzem uma toxina altamente resistente, denominada cereulida. Esta toxina é o agente responsável por uma intoxicação alimentar caracterizada por emese. A cereulida é um dodecadepsipéptido cíclico com uma estrutura semelhante à da valinomicina, um composto antimicrobiano produzido por Streptomyces spp. Ambos os compostos são ionóforos de potássio, facilitando o movimento the K+ através das membranas celulares com concomitante dissipação do potencial de membrana. Devido às suas propriedades ionofóricas, a valinomicina
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20

Salerno, Tatiana [UNESP]. "Avaliação microbiológica, físico-química e detecção de resíduos de antimicrobianos em leite humano, bovino e caprino e pesquisa de toxinas em linhagens de Staphylococcus spp." Universidade Estadual Paulista (UNESP), 2011. http://hdl.handle.net/11449/106026.

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Made available in DSpace on 2014-06-11T19:35:13Z (GMT). No. of bitstreams: 0 Previous issue date: 2011-09-02Bitstream added on 2014-06-13T20:06:47Z : No. of bitstreams: 1 salerno_t_dr_botfmvz.pdf: 1479294 bytes, checksum: 37333e3500ad6a6f49d6aabf4f562cf3 (MD5)<br>Fundação de Amparo à Pesquisa do Estado de São Paulo (FAPESP)<br>O presente estudo avaliou a qualidade microbiológica, as características físicoquímicas e a presença de resíduos de antimicrobianos em leite de mulheres, vacas e cabras, bem como investigou a multirresistência bacteriana à antimicrobianos e a detecção de genes e produç
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21

Salerno, Tatiana. "Avaliação microbiológica, físico-química e detecção de resíduos de antimicrobianos em leite humano, bovino e caprino e pesquisa de toxinas em linhagens de Staphylococcus spp. /." Botucatu : [s.n.], 2011. http://hdl.handle.net/11449/106026.

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Orientador: Márcio Garcia Ribeiro<br>Coorientador: José Paes de Almeida Nogueira Pinto<br>Banca: Antonio Carlos Paes<br>Banca: Hélio Langoni<br>Banca: Maria de Lourdes Ribeiro de Souza da Cunha<br>Banca: Nilson Roberti Benites<br>Resumo: O presente estudo avaliou a qualidade microbiológica, as características físicoquímicas e a presença de resíduos de antimicrobianos em leite de mulheres, vacas e cabras, bem como investigou a multirresistência bacteriana à antimicrobianos e a detecção de genes e produção de toxinas em linhagens de Staphylococcus spp. Foram colhidas 240 amostras de leite de mul
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22

Bott, Charles Briddell. "Elucidating the Role of Toxin-Induced Microbial Stress Responses in Biological Wastewater Treatment Process Upset." Diss., Virginia Tech, 2001. http://hdl.handle.net/10919/26641.

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The overall hypothesis of this work is that the physiological microbial stress response could serve as a rapid, sensitive, and mechanistically-based indicator of process upset in biological wastewater treatment systems that receive sporadic shock loads of toxic chemicals. The microbial stress response is a set of conserved and unique biochemical mechanisms that an organism activates or induces under adverse conditions, specifically for the protection of cellular components or the repair of damaged macromolecules. Using traditional immunochemical analysis techniques, the heat shock protein, G
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23

Larose, Delphine. "Shiga Toxin-producing Escherichia Coli (STEC) : development of an immuno-detection method and a direct-fed microbial to control their prevalence in cattle." Thesis, Dijon, 2016. http://www.theses.fr/2016DIJOS013.

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Les Escherichia coli enterohémorragiques (EHEC) sont responsables de maladies graves comme la colitehémorragique (CH), le syndrome hémolytique et urémique (SHU) ou le purpura thrombotiquethrombocytopénique (PTT). Les infections humaines sont principalement dues à la consommationd’aliments contaminés, en particulier la viande d’origine bovine, le lait ou les légumes. Le principalréservoir naturel des EHEC est le tractus gastro-intestinal (TGI) des bovins. Les fèces de bovins sont, parconséquent, responsables de la contamination de plusieurs types d’aliments mais également de ladissémination env
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Ястремська, Лариса Сергіївна, І. Прекрасна, О. Таширев, and г. Снєгур. "Resistance of Negev desert microbial community to Cu2+ and Hg2+." Thesis, National Aviation University, 2013. http://er.nau.edu.ua/handle/NAU/38607.

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The aim of the work is to evaluate the ability to keep stabile functioning of microbial community of Negev Desert clay (Israel) in the presence of typical for damaging effect toxic metals - Cu2 + and Hg2+ . The results show the stability of Negev desert microbial community to the extremely high bactericidal concentrations of toxic metals (1000 mg/l Cu2+and 10 mg/l Hg2+), despite the trace concentrations of these metals (0,23 mg/l Cu2+) in the desert ecosystem. This indicates a high resistance and ability of microbial cenosis to adapt to extreme factors. It can be supposed, ac
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Driscoll, William Wallace. "Social and Asocial Niche Construction in Microbial Populations." Diss., The University of Arizona, 2012. http://hdl.handle.net/10150/228457.

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Cooperation presents a major challenge for evolutionary theory: how can competition favor a trait that imposes a cost on the individual expressing it while benefitting another? This challenge has been answered by theory that emphasizes the importance of assortment between individuals that tend to cooperate and those who tend to behave selfishly, or `cheat'. Microbial cooperation remains puzzling, given the generally high genetic and taxonomic diversity of most microbial communities. Many microbial populations rely on shared, beneficial extracellular products for an array of functions in nat
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Meng, Guangxun. "Cellular recognition of microbial patterns through toll-like receptor (TLR) 2 analysis of molecular requirements and monoclonal antibody mediated blockage /." [S.l.] : [s.n.], 2004. http://deposit.ddb.de/cgi-bin/dokserv?idn=973389672.

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27

Pujol, Vila Ferran. "Fast and low-cost microbial toxicity bioassays based on electrochromic electron acceptors." Doctoral thesis, Universitat Autònoma de Barcelona, 2017. http://hdl.handle.net/10803/456178.

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This thesis proposes the use of compounds that change their colour when reduced by living cells, i.e. electrochromic electron acceptors, in the development of fast and low-cost microbial toxicity bioassays suitable for in situ analysis. Electrochromism enables the monitoring of cell respiration by simple colorimetric measurement or even with the bare eye. Thus, allowing for toxicity determination without the need for complex instrumentation. Hexacyanoferrate compounds have been selected from the wide spectrum of reported electrochromic electron acceptors due to their suitable solubility and st
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Pyne, S. "Studies of microbial slime formation on toxic and non-toxic surfaces with special reference to diatom fouling of in-service vessels." Thesis, University of Portsmouth, 1987. http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.376461.

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Sertkaya, Abdullah. "Investigation Of Cytocidal Effect Of K5 Type Yeast Killer Protein On Sensitive Microbial Cells." Master's thesis, METU, 2005. http://etd.lib.metu.edu.tr/upload/12606604/index.pdf.

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Some yeasts secrete polypeptide toxins, which are lethal to other sensitive yeast cells, gram-positive pathogenic bacteria and pathogenic fungi. Therefore these are designated as killer toxins. Killer toxins are suggested as potent antimicrobial agents especially for the protection of fermentation process against contaminating yeasts, biological control of undesirable yeasts in the preservation of foods. Moreover they are promising antimicrobial agents in the medical field<br>due to immune system suppressing diseases like AIDS, there is an increase in the incidence of fungal diseases and curre
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Yang, Ke. "Anaerobic treatment of a metalworking fluid and overcoming the toxic effects on the biodegradation process." Thesis, University of Oxford, 2016. http://ora.ox.ac.uk/objects/uuid:fae32f24-e9f6-48df-9135-8ccca639dd86.

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Metalworking fluids (MWFs) are petroleum emulsions employed for metal machining processes as coolants and lubricants. To date, they have been irreplaceable in modern heavy and manufacturing industries, with annual usage exceeding two billion litres worldwide. However, the large amount of MWFs, the highly concentrated complex recalcitrant and toxic petroleum components contained in them continue to cause significant concern in terms of sustainable routes of end-of-life treatment and disposal. Compared with other treatment methods, the anaerobic treatment method has significant advantages, such
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bhardwaj, vinay. "Label-free surface-enhanced Raman spectroscopy-linked immunosensor assay (SLISA) for environmental surveillance." FIU Digital Commons, 2015. http://digitalcommons.fiu.edu/etd/2321.

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The contamination of the environment, accidental or intentional, in particular with chemical toxins such as industrial chemicals and chemical warfare agents has increased public fear. There is a critical requirement for the continuous detection of toxins present at very low levels in the environment. Indeed, some ultra-sensitive analytical techniques already exist, for example chromatography and mass spectroscopy, which are approved by the US Environmental Protection Agency for the detection of toxins. However, these techniques are limited to the detection of known toxins. Cellular expression
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Ekong, Pius Stephen. "Data collection, analysis and development of a peri-harvest quantitative microbial risk assessment (QMRA) for Shiga toxin-producing Escherichia coli (STEC) in beef production." Diss., Kansas State University, 2017. http://hdl.handle.net/2097/38163.

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Doctor of Philosophy<br>Department of Diagnostic Medicine/Pathobiology<br>Michael W. Sanderson<br>Shiga-toxin-producing Escherichia coli (STEC), of which enterohemorrhagic E. coli (EHEC) are a pathogenic sub-group, are foodborne pathogens of significant public health importance in the United States. STEC belong to the family Enterobacteriaceae commonly found in the large intestine of humans and other warm-blooded animals. EHEC harbors shiga toxin (stx1 and/or stx2) and eae genes which confers the ability to cause human illnesses. The U.S. Department of Agriculture Food Safety and Inspection Se
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Avanzi, Ingrid Regina. "Estudo da atividade microbiana na biorremediação de metais tóxicos na região Amazônica." Universidade de São Paulo, 2016. http://www.teses.usp.br/teses/disponiveis/106/106132/tde-21022017-153529/.

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Nas últimas décadas o crescimento industrial decorrente do desenvolvimento tecnológico e outras atividades consideradas indispensáveis à vida humana, estão gerando graves problemas ambientais, que está despertando uma preocupação a nível mundial. Dentre os vários contaminantes os metais tóxicos têm recebido atenção especial, pela sua persistência ao ingressar nos ecossistemas acumulando-se por toda a cadeia alimentar, uma vez que são extremamente tóxicos, mesmo em quantidades muito baixas. No Brasil, a legislação ambiental vigente já estabele
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Montillet, Jean-Luc. "Dosage radioimmunologique du zinniol : application a l'etude de cette toxine dans l'alternariose de la carotte." Toulouse 3, 1986. http://www.theses.fr/1986TOU30208.

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Un dosage radioimmunologique specifique du zinniol a ete au point; les etapes de ce travail ont ete les suivantes: - synthese d'une molecule immunogene (conjugue zinniol-proteine porteuse). - obtention d'anticorps specifique (4 ci/mmole). - mise au point du dosage radioimmunologique valide du point de vue de sa specificite, de sa reproductibilite et de sa sensibilite (limite de detection 0,14 nn/essai). Cet outil a permis de realiser des dosages sur des plantes infectees. Ces resultats inedits montrent que la molecule est emise tres rapidement dans les tissus infectes (12 h apres inoculation).
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Mohammed, Fatima Sule. "Indoor and outdoor dust in Damaturu Nigeria : composition, exposure and risk to human health." Thesis, Cranfield University, 2013. http://dspace.lib.cranfield.ac.uk/handle/1826/8376.

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Harmattan and Dust (sand) storms together with anthropogenic activities including the use of firewood and kerosene as fuel for cooking, and diesel/petrol generators for electricity generation are potential sources of particulate and gaseous pollutants in homes in Damaturu town, Nigeria. Other activities like the burning of locally produced incense and mosquito coils as well as the use of aerosol sprays are further possible sources of indoor pollution, which may result in exposure of people to a range of pollutants through inhalation, by ingestion of settled dusts as well as dermal contact. Loc
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Ducourneau, Christine. "Isolement et etude d'effets physiologiques d'une toxine produite par xanthomonas campestris pv. Vasculorum, agent de la gommose de la canne a sucre." Toulouse 3, 1986. http://www.theses.fr/1986TOU30233.

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Xanthomonas campestris pv. Vasculorum produit in vivo une phytotoxine tres hydrophile. L'ensemble de ce travail a consiste a: isoler et purifier cette toxine, apporter des informations sur sa structure et nature chimique, mettre en evidence sa specificite d'interaction vis-a-vis d'une molecule affine presente chez les plantes hotes; les effets physiologiques qu'elle induit dans les cellules de l'hote. Ces derniers resultats contribuent a mieux approcher son mecanisme biochimique d'action qui se manifeste sur les hotes potentiels, a des niveaux d'organisation differents (tissu foliaire et proto
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Triplett, Charla K. "A model system to study the effects of methylglyoxal on the yield and quality of tissue plasminogen activator produced by CHO cells." Thesis, 1999. http://hdl.handle.net/1957/33264.

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In this research, a model system for studying the effects of the toxic metabolite, methylglyoxal, was created using Chinese Hamster Ovary (CHO) cells which produce tissue plasminogen activator (t-PA). The human gene for glyoxalase I was subcloned into an inducible mammalian expression vector. This vector was then used to create three stable CHO integrants, two control and one putative glyoxalase I producing cell lines. The CHO clones were characterized for the production of glyoxalase I using both SDS-PAGE gels and glyoxalase activity assays. In addition, the cell lines were evaluated to deter
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Garcia, Andreia Sofia Rodrigues. "Influence of uremic toxins on microbial intestinal epithelial barrier translocation in chronic kidney disease." Master's thesis, 2019. http://hdl.handle.net/10773/28406.

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Chronic kidney disease (CKD) is a general term for disorders affecting kidney structure and function. The progressive loss of renal function leads to the accumulation of toxins, the uremic toxins, normally cleared by the kidneys. It is under these circumstances that the “uremic state” is established. Recent studies relate uremic plasma to impaired intestinal barrier function and to depletion of the tight junctions (TJs) protein constituents. Within the intestinal lumen urea is hydrolyzed by microbial urease forming large quantities of ammonia, the major mediator of intestinal barrier disruptio
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Jungblut, Anne Dorothee Biotechnology &amp Biomolecular Sciences Faculty of Science UNSW. "Characterisation of microbial Mat communities in meltwater ponds of the McMurdo ice shelf, Antarctica." 2007. http://handle.unsw.edu.au/1959.4/40496.

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The investigation presented in this thesis examined the microbial and functional diversity of the meltwater ponds Fresh, Orange and Salt Ponds on the McMurdo Ice Shelf, near Bratina Island, Antarctica. These sites were chosen because of the ecological importance and absence of detailed characterisations of their diversity and function as part of Antarctica?s largest wetland. Particular focus was on cyanobacterial diversity, nitrogen fixation and secondary metabolite production. Using 16S rRNA gene and morphological analysis a large diversity of cyanobacteria (more than 22 phylotypes) was ident
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Lee, Chi-An. "Distribution of Enterotoxigenic Clostridium perfringens Spores in U.S. Retail Spices." 2016. https://scholarworks.umass.edu/masters_theses_2/427.

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246 samples of bulk and packaged spices from retail stores in the western, southeastern, southern, midwestern, and northeastern areas of the U.S. were examined for the presence of Clostridium -perfringens. Isolates were checked for the presence of the lecithinase gene (cpa) and enterotoxin genes (cpe) by PCR. Enterotoxin formation during sporulation was investigated using the Oxoid Toxin Detection Kit. Forty-three confirmed isolates (from 17% of total samples) were cpa-positive. Of those, 27 were cpe-positive. Together, levels of C. perfringens spores ranged from 3.6-2400/gm. The amount of ent
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Bruder, Slawa Romana. "Prediction of Spatial-Temporal Distribution of Algal Metabolites in Eagle Creek Reservoir, Indianapolis, IN." Thesis, 2012. http://hdl.handle.net/1805/3043.

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Indiana University-Purdue University Indianapolis (IUPUI)<br>In this research, Environmental Fluid Dynamic Code (EFDC) and Adaptive- Networkbased Fuzzy Inference System Models (ANFIS) were developed and implemented to determine the spatial-temporal distribution of cyanobacterial metabolites: 2-MIB and geosmin, in Eagle Creek Reservoir, IN. The research is based on the current need for understanding algae dynamics and developing prediction methods for algal taste and odor release events. In this research the methodology for prediction of 2-MIB and geosmin production was explored. The app
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Redelman, Carly Virginia. "Antibiotic Treatment of Pseudomonas aeruginosa Biofilms Stimulates Expression of mgtE, a Virulence Modulator." 2012. http://hdl.handle.net/1805/2887.

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Indiana University-Purdue University Indianapolis (IUPUI)<br>Pseudomonas aeruginosa is a gram negative opportunistic pathogen with the capacity to cause serious disease by forming biofilms, most notably in the lungs of cystic fibrosis (CF) patients. Biofilms are communities of microorganisms that adhere to a solid surface, undergo global regulatory changes, secrete exopolysaccharides, and are innately antibiotic resistant. Virulence modulation is an important tool utilized by P. aeruginosa to propagate infection and biofilm formation in the CF airway. Many different virulence modulatory pat
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Rinta-Kanto, Johanna Maaria. "Biogeography and Genetic Diversity of Toxin Producing Cyanobacteria in a Laurentian Great Lake." 2007. http://trace.tennessee.edu/utk_graddiss/276.

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The North American Great Lakes are a vital source on a global scale, as they hold ~18 % of the potable water resources on our planet. Cyanobacteria of the genus Microcystis are commonly found in fresh water environments around the world, and since the mid-1990s also in Lake Erie. The reasons for the success for these potentially toxic cyanobacteria in Lake Erie are not completely understood. In this study we have applied modern molecular tools to analyze field samples to provide an insight into the genotypic composition and diversity of the Microcystis community in the past and present day Lak
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ZHANG, ZAN-CHANG, and 張讚昌. "Studies on the microbial degradation of organic chlorinated toxic compound." Thesis, 1991. http://ndltd.ncl.edu.tw/handle/71176170861989014233.

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Poleo, Eduardo E. "SIMULTANEOUS DEGRADATION OF TOXIC AND VOLATILE SUBSTRATES BY TWO PHASE PARTITIONING BIOREACTOR SYSTEMS: PERFORMANCE CHARACTERIZATION AND RATIONAL POLYMER SELECTION." Thesis, 2013. http://hdl.handle.net/1974/8018.

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The degradation of toxic and volatile contaminants in aqueous streams is considered a challenge using conventional bioremediation strategies. At moderate concentrations, toxic contaminants induce microbial inhibition, which results in an overall decrease of reaction rates. On the other hand, volatile compounds are often stripped out of solution into the atmosphere during aeration in conventional wastewater treatments, and are not treated. The addition of a second non-aqueous phase with affinities for the contaminants can reduce aqueous concentrations to sub-inhibitory levels and also decrease
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Vimalnath, S. "Bioremediation of Lead from Aqueous Solutions using Pseudomonas Species - Mechanisms & Biosensor Applications." Thesis, 2015. http://etd.iisc.ac.in/handle/2005/4118.

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Industrialization, urbanization and technological developments have improved the standard of living for humans on the one hand, but they also have resulted in the generation of wastes containing toxic heavy metals that are detrimental to the ecosystem on the other hand. Therefore, the treatment of waste water containing toxic heavy metals before discharging into the environment has become imperative. Though, the conventional waste water treatment methods like adsorption, electrochemical process, ion-exchange, precipitation, solvent extraction, etc. have served the purpose of removing toxic hea
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McCanna, David. "Development of Sensitive In Vitro Assays to Assess the Ocular Toxicity Potential of Chemicals and Ophthalmic Products." Thesis, 2009. http://hdl.handle.net/10012/4338.

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The utilization of in vitro tests with a tiered testing strategy for detection of mild ocular irritants can reduce the use of animals for testing, provide mechanistic data on toxic effects, and reduce the uncertainty associated with dose selection for clinical trials. The first section of this thesis describes how in vitro methods can be used to improve the prediction of the toxicity of chemicals and ophthalmic products. The proper utilization of in vitro methods can accurately predict toxic threshold levels and reduce animal use in product development. Sections two, three and four describe t
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