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Journal articles on the topic 'Microchip CE'

Author: Grafiati

Published: 4 June 2021

Last updated: 1 February 2022

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1

Li, Sam FY, and Larry J. Kricka. "Clinical Analysis by Microchip Capillary Electrophoresis." Clinical Chemistry 52, no. 1 (January 1, 2006): 37–45. http://dx.doi.org/10.1373/clinchem.2005.059600.

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Abstract Clinical analysis often requires rapid, automated, and high-throughput analytical systems. Microchip capillary electrophoresis (CE) has the potential to achieve very rapid analysis (typically seconds), easy integration of multiple analytical steps, and parallel operation. Although it is currently still in an early stage of development, there are already many reports in the literature describing the applications of microchip CE in clinical analysis. At the same time, more fully automated and higher throughput commercial instruments for microchip CE are becoming available and are expected to further enhance the development of applications of microchip CE in routine clinical testing. To put into perspective its potential, we briefly compare microchip CE with conventional CE and review developments in this technique that may be useful in diagnosis of major diseases.

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2

Vrouwe, Elwin X., Regina Luttge, Istvan Vermes, and Albert van den Berg. "Microchip Capillary Electrophoresis for Point-of-Care Analysis of Lithium." Clinical Chemistry 53, no. 1 (January 1, 2007): 117–23. http://dx.doi.org/10.1373/clinchem.2007.073726.

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Abstract Background: Microchip capillary electrophoresis (CE) is a promising method for chemical analysis of complex samples such as whole blood. We evaluated the method for point-of-care testing of lithium. Methods: Chemical separation was performed on standard glass microchip CE devices with a conductivity detector as described in previous work. Here we demonstrate a new sample-to-chip interface. Initially, we took a glass capillary as a sample collector for whole blood from a finger stick. In addition, we designed a novel disposable sample collector and tested it against the clinical standard at the hospital (Medisch Spectrum Twente). Both types of collectors require <10 μL of test fluid. The collectors contain an integrated filter membrane, which prevents the transfer of blood cells into the microchip. The combination of such a sample collector with microchip CE allows point-of-care measurements without the need for off-chip sample treatment. This new on-chip protocol was verified against routine lithium testing of 5 patients in the hospital. Results: Sodium, lithium, magnesium, and calcium were separated in <20 s. The detection limit for lithium was 0.15 mmol/L. Conclusions: The new microchip CE system provides a convenient and rapid method for point-of-care testing of electrolytes in serum and whole blood.

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3

Tian, Huijun, Lawrence C. Brody, Saijun Fan, Zhili Huang, and James P. Landers. "Capillary and Microchip Electrophoresis for Rapid Detection of Known Mutations by Combining Allele-specific DNA Amplification with Heteroduplex Analysis." Clinical Chemistry 47, no. 2 (February 1, 2001): 173–85. http://dx.doi.org/10.1093/clinchem/47.2.173.

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Abstract Background: Detection of mutations by gel electrophoresis and allele-specific amplification by PCR (AS-PCR) is not easily scaled to accommodate a large number of samples. Alternative electrophoretic formats, such as capillary electrophoresis (CE) and microchip electrophoresis, may provide powerful platforms for simple, fast, automated, and high-throughput mutation detection after allele-specific amplification. Methods: DNA samples heterozygous for four mutations (185delAG, 5382insC, 3867G→T, and 6174delT) in BRCA1 and BRCA2, and homozygous for one mutation (5382insC) in BRCA1 and two mutations (16delAA and 822delG) in PTEN were chosen as the model system to evaluate the capillary and microchip electrophoresis methods. To detect each mutation, three primers, of which one was labeled with the fluorescent dye 6-carboxyfluorescein and one was the allele-specific primer (mutation-specific primer), were used to amplify the DNA fragments in the range of 130–320 bp. AS-PCR was combined with heteroduplex (HD) analysis, where the DNA fragments obtained by AS-PCR were analyzed with the conditions developed for CE-based HD analysis (using a fluorocarbon-coated capillary and hydroxyethylcellulose). The CE conditions were transferred into the microchip electrophoresis format. Results: Three genotypes, homozygous wild type, homozygous mutant, and heterozygous mutant, could be identified by CE-based AS-PCR-HD analysis after 10–25 min of analysis time. Using the conditions optimized with CE, we translated the AS-PCR-HD analysis mutation detection method to the microchip electrophoresis format. The detection of three heterozygous mutations (insertion, deletion, and substitution) in BRCA1 could be accomplished in 180 s or less. Conclusions: It is possible to develop a CE-based method that exploits both AS-PCR and HD analysis for detecting specific mutations. Fast separation and the capacity for automated operation create the potential for developing a powerful electrophoresis-based mutation detection system. Fabrication of multichannel microchip platforms may enable mutation detection with high throughput.

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4

Chen, Yu-Hung, Wei-Chang Wang, Kung-Chia Young, Ting-Tsung Chang, and Shu-Hui Chen. "Plastic Microchip Electrophoresis for Analysis of PCR Products of Hepatitis C Virus." Clinical Chemistry 45, no. 11 (November 1, 1999): 1938–43. http://dx.doi.org/10.1093/clinchem/45.11.1938.

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Abstract Background: Electrophoresis on polymeric rather than glass microstructures is a promising separation method for analytical chemistry. Assays on such devices need to be explored to allow assessment of their utility for the clinical laboratory. Methods: We compared capillary and plastic microchip electrophoresis for clinical post-PCR analysis of hepatitis C virus (HCV). For capillary electrophoresis (CE), we used a separation medium composed of 10 g/L hydroxypropyl methyl cellulose in Tris-borate-EDTA buffer and 10 μmol/L intercalating dye. For microchip electrophoresis, the HCV assay established on the fused silica tubing was transferred to the untreated polymethylmethacrylate microchip with minimum modifications. Results: CE resolved the 145-bp amplicon of HCV in 15 min. The confidence interval of the migration time was <3.2%. The same HCV amplicon was resolved by microchip electrophoresis in <1.5 min with the confidence interval of the migration time <1.3%. Conclusion: The polymer microchip, with advantages that include fast processing time, simple operation, and disposable use, holds great potential for clinical analysis.

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5

Wang, Yineng, Xi Cao, Walter Messina, Anna Hogan, Justina Ugwah, Hanan Alatawi, Ed van Zalen, and Eric Moore. "Development of a Mobile Analytical Chemistry Workstation Using a Silicon Electrochromatography Microchip and Capacitively Coupled Contactless Conductivity Detector." Micromachines 12, no. 3 (February 27, 2021): 239. http://dx.doi.org/10.3390/mi12030239.

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Capillary electrochromatography (CEC) is a separation technique that hybridizes liquid chromatography (LC) and capillary electrophoresis (CE). The selectivity offered by LC stationary phase results in rapid separations, high efficiency, high selectivity, minimal analyte and buffer consumption. Chip-based CE and CEC separation techniques are also gaining interest, as the microchip can provide precise on-chip control over the experiment. Capacitively coupled contactless conductivity detection (C4D) offers the contactless electrode configuration, and thus is not in contact with the solutions under investigation. This prevents contamination, so it can be easy to use as well as maintain. This study investigated a chip-based CE/CEC with C4D technique, including silicon-based microfluidic device fabrication processes with packaging, design and optimization. It also examined the compatibility of the silicon-based CEC microchip interfaced with C4D. In this paper, the authors demonstrated a nanofabrication technique for a novel microchip electrochromatography (MEC) device, whose capability is to be used as a mobile analytical equipment. This research investigated using samples of potassium ions, sodium ions and aspirin (acetylsalicylic acid).

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6

Silvertand, L. H. H., E. Machtejevas, R. Hendriks, K. K. Unger, W. P. van Bennekom, and G. J. de Jong. "Selective protein removal and desalting using microchip CE." Journal of Chromatography B 839, no. 1-2 (July 2006): 68–73. http://dx.doi.org/10.1016/j.jchromb.2006.03.036.

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7

Sikanen, T., S. Tuomikoski, R. A. Ketola, R. Kostiainen, S. Franssila, and T. Kotiaho. "Microchip-based CE-ESI/MS analysis of biological molecules." European Journal of Pharmaceutical Sciences 34, no. 1 (June 2008): S37. http://dx.doi.org/10.1016/j.ejps.2008.02.103.

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8

LI, GANG, GUI-SHENG ZHUANG, HONG-BO ZHOU, JIAN-LONG ZHAO, and YUAN-SEN XU. "A SANDWICH-INJECTION METHOD FOR MICROCHIP ELECTROPHORESIS." Nano 02, no. 06 (December 2007): 373–81. http://dx.doi.org/10.1142/s1793292007000738.

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In microchip electrophoresis (μ-CE), sample injection is generally achieved through cross, double-T, or T-form injector structures. In these reported approaches, the separation efficiency and detection sensitivity of μ-CE is significantly influenced by the shape and size of the sample plug introduced into the separation channel or sample leakage in separation phase. Here, we present a sandwich-injection method for controlling discrete sample injection in μ-CE. This method involves four accessory arm channels in which symmetrical potentials are loaded to form a unique parallel electric field distribution at the intersection of sample and separation channels. The parallel electric field effectuate a virtual wall to confine the shape of a sample plug and depress the spreading of the sample plug at the junction of sample and separation channels, and also prevent sample leakage during separation step. The key features of this method are the ability to inject well-defined sample plugs at the original sample concentration and the ability to control the sample plug size. The virtues of the novel injection technique were demonstrated with numerical models and validated with fluorescence visualizations of electrophoretic experiments.

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9

Gong, Maojun, Ning Zhang, and Naveen Maddukuri. "Flow-gated capillary electrophoresis: a powerful technique for rapid and efficient chemical separation." Analytical Methods 10, no. 26 (2018): 3131–43. http://dx.doi.org/10.1039/c8ay00979a.

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Flow-gated capillary electrophoresis (CE) is a hybrid of conventional and microchip CE since it employs a fused silica capillary as the separation channel while taking advantage of the well-controlled flow-gated injection, which adds versatility in terms of separation efficiency, analytical throughput, and ease of coupling with sample pretreatment procedures.

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10

Phillips, Terry M. "Recent advances in CE and microchip-CE in clinical applications: 2014 to mid-2017." ELECTROPHORESIS 39, no. 1 (September 20, 2017): 126–35. http://dx.doi.org/10.1002/elps.201700283.

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11

Bowes, Cathy. "High throughput analysis of N-glycans on microchip-CE platform." Drug Discovery Today 16, no. 23-24 (December 2011): 1093. http://dx.doi.org/10.1016/j.drudis.2011.10.014.

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12

Buyuktuncel, Ebru. "Microchip Electrophoresis and Bioanalytical Applications." Current Pharmaceutical Analysis 15, no. 2 (January 4, 2019): 109–20. http://dx.doi.org/10.2174/1573412914666180831100533.

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Microanalytical systems have aroused great interest because they can analyze extremely small sample volumes, improve the rate and throughput of chemical and biochemical analysis in a way that reduces costs. Microchip Electrophoresis (ME) represents an effective separation technique to perform quick analytical separations of complex samples. It offers high resolution and significant peak capacity. ME is used in many areas, including biology, chemistry, engineering, and medicine. It is established the same working principles as Capillary Electrophoresis (CE). It is possible to perform electrophoresis in a more direct and convenient way in a microchip. Since the electric field is the driving force of the electrodes, there is no need for high pressure as in chromatography. The amount of the voltage that is applied in some electrophoresis modes, e.g. Micelle Electrokinetic Chromatography (MEKC) and Capillary Zone Electrophoresis (CZE), mainly determines separation efficiency. Therefore, it is possible to apply a higher electric field along a considerably shorter separation channel, hence it is possible to carry out ME much quicker.

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13

Gilliland, William M., and J. Michael Ramsey. "Development of a Microchip CE-HPMS Platform for Cell Growth Monitoring." Analytical Chemistry 90, no. 21 (October 17, 2018): 13000–13006. http://dx.doi.org/10.1021/acs.analchem.8b03708.

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14

Pumera, Martin. "Trends in analysis of explosives by microchip electrophoresis and conventional CE." ELECTROPHORESIS 29, no. 1 (January 2008): 269–73. http://dx.doi.org/10.1002/elps.200700394.

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15

Zhuang, Gui-Sheng, Gang Li, Qing-Hui Jin, Jian-Long Zhao, and Meng-Su Yang. "Numerical analysis of an electrokinetic double-focusing injection technique for microchip CE." ELECTROPHORESIS 27, no. 24 (December 2006): 5009–19. http://dx.doi.org/10.1002/elps.200600282.

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16

Gong, Maojun, Kenneth R. Wehmeyer, Apryll M. Stalcup, Patrick A. Limbach, and William R. Heineman. "Study of injection bias in a simple hydrodynamic injection in microchip CE." ELECTROPHORESIS 28, no. 10 (May 2007): 1564–71. http://dx.doi.org/10.1002/elps.200600616.

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17

Wang, Wei, Liang Zhao, Fang Zhou, Jian-Rong Zhang, Jun-Jie Zhu, and Hong-Yuan Chen. "Low EOF rate measurement based on constant effective mobility in microchip CE." ELECTROPHORESIS 28, no. 16 (August 2007): 2893–96. http://dx.doi.org/10.1002/elps.200600781.

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18

Chen, Jin, Yu Sun, Xiaogai Peng, Yi Ni, Fengchao Wang, and Xiaoming Dou. "Rapid Analysis for Staphylococcus aureus via Microchip Capillary Electrophoresis." Sensors 21, no. 4 (February 13, 2021): 1334. http://dx.doi.org/10.3390/s21041334.

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Staphylococcus aureus (S. aureus) is one of the most common pathogens for nosocomial and community infections, which is closely related to the occurrence of pyogenic and toxic diseases in human beings. In the current study, a lab-built microchip capillary electrophoresis (microchip CE) system was employed for the rapid determination of S. aureus, while a simple-to-use space domain internal standard (SDIS) method was carried out for the reliable quantitative analysis. The precision, accuracy, and reliability of SDIS were investigated in detail. Noted that these properties could be elevated in SDIS compared with traditional IS method. Remarkably, the PCR products of S. aureusnuc gene could be identified and quantitated within 80 s. The theoretical detection limit could achieve a value of 0.066 ng/μL, determined by the using SDIS method. The current work may provide a promising detection strategy for the high-speed and highly efficient analysis of pathogens in the fields of food safety and clinical diagnosis.

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19

Garcia, Carlos D., and Charles S. Henry. "Direct detection of renal function markers using microchip CE with pulsed electrochemical detection." Analyst 129, no. 7 (2004): 579. http://dx.doi.org/10.1039/b403529a.

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20

Lu, Qin, Peter Wu, and Greg E. Collins. "Contactless conductivity detection of sodium monofluoroacetate in fruit juices on a CE microchip." ELECTROPHORESIS 28, no. 19 (October 2007): 3485–91. http://dx.doi.org/10.1002/elps.200600723.

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21

Shin, Giyoung, Dong-Kyun Kim, Junsang Doh, Daeyeon Lee, Nam Ki Lee, and Gyoo Yeol Jung. "High-resolution pluronic-filled microchip CE-SSCP analysis system via channel width control." ELECTROPHORESIS 37, no. 4 (November 30, 2015): 676–79. http://dx.doi.org/10.1002/elps.201500427.

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22

Colombo, Raffaella, and Adele Papetti. "Pre-Concentration and Analysis of Mycotoxins in Food Samples by Capillary Electrophoresis." Molecules 25, no. 15 (July 29, 2020): 3441. http://dx.doi.org/10.3390/molecules25153441.

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Mycotoxins are considered one of the most dangerous agricultural and food contaminants. They are toxic and the development of rapid and sensitive analytical methods to detect and quantify them is a very important issue in the context of food safety and animal/human health. The need to detect mycotoxins at trace levels and to simultaneously analyze many different mycotoxin types became mandatory to protect public health. In fact, European Commission regulations specified both their limits in foodstuffs and official sample preparation protocols in addition to analytical methods to verify their presence. Capillary Electrophoresis (CE) includes different separation modes, allowing many versatile applications in food analysis and safety. In the context of mycotoxins, recent advances to improve CE sensitivity, particularly pre-concentration techniques or miniaturized systems, deserve remarkable attention, as they provide an interesting approach in the analysis of such contaminants in complex food matrices. This review summarizes the applications of CE combined with different pre-concentration approaches, which have been proposed in the literature (mainly) in the last ten years. A section is also dedicated to recent microchip–CE devices since they represent the most promising CE mode for this application.

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23

OHTSUKA, Kei-ichirou, Nobuhiko IKI, Hitoshi HOSHINO, and Toru TAKAHASHI. "Dissociation Kinetic Analysis of Ce(III) Complex with Quin2 by Microchip Capillary Electrophoretic Reactor." Analytical Sciences 29, no. 5 (2013): 553–57. http://dx.doi.org/10.2116/analsci.29.553.

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24

Wu, Ruige, Zhiping Wang, Ying Sing Fung, Daphne Yen Peng Seah, and William Shu-Biu Yeung. "Assessment of adulteration of soybean proteins in dairy products by 2D microchip-CE device." ELECTROPHORESIS 35, no. 11 (February 24, 2014): 1728–34. http://dx.doi.org/10.1002/elps.201300559.

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25

Liu, Xiaojun, Ming Du, Feimeng Zhou, and Frank A. Gomez. "Facile fabrication of an interface for online coupling of microchip CE to surface plasmon resonance." Bioanalysis 4, no. 4 (February 2012): 373–79. http://dx.doi.org/10.4155/bio.12.4.

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26

Ding, Yongsheng, and Carlos D. Garcia. "Application of microchip-CE electrophoresis to follow the degradation of phenolic acids by aquatic plants." ELECTROPHORESIS 27, no. 24 (December 2006): 5119–27. http://dx.doi.org/10.1002/elps.200600081.

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27

Wang, Wei, Liang Zhao, Li-Ping Jiang, Jian-Rong Zhang, Jun-Jie Zhu, and Hong-Yuan Chen. "EOF measurement by detection of a sampling zone with end-channel amperometry in microchip CE." ELECTROPHORESIS 27, no. 24 (December 2006): 5132–37. http://dx.doi.org/10.1002/elps.200600110.

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28

Wang, Wei, Fang Zhou, Liang Zhao, Jian-Rong Zhang, and Jun-Jie Zhu. "Improved hydrostatic pressure sample injection by tilting the microchip towards the disposable miniaturized CE device." ELECTROPHORESIS 29, no. 3 (February 2008): 561–66. http://dx.doi.org/10.1002/elps.200700207.

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29

Kim, J. W., A. K. Lee, M. S. Jeoung, J. Y. Lee, and J. G. Choi. "A New Development of Photoacoustic Detection for Microchip-CE Using a Simple Pick-up Device." International Journal of Thermophysics 29, no. 6 (July 25, 2008): 2162–68. http://dx.doi.org/10.1007/s10765-008-0486-x.

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30

Li, Yongru, Hongwei Su, and Yajia Lan. "Simultaneous Detection of Yersinia Enterocolitica and Listeria Monocytogenes in Foodstuffs by Capillary Electrophoresis and Microchip Capillary Electrophoresis Laser-Induced Fluorescence Detector." Journal of AOAC INTERNATIONAL 101, no. 6 (November 1, 2018): 1833–38. http://dx.doi.org/10.5740/jaoacint.17-0507.

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Abstract Background: Food safety is one of the most important public health problems in the world, and pathogenic bacterium is a major factor causing serious foodborne diseases. Objective: Two methods of duplex PCR combined with capillary electrophoresis laser-induced fluorescence detector (CE-LIF) and microchip capillary electrophoresis laser-induced fluorescence detector (MCE-LIF) have been developed for the simultaneous detection of Yersinia Enterocolitica and Listeria Monocytogenes in various foods. The specific conservative sequences of these two bacteria were amplified. Methods: After labelled with nucleic acid dye SYBR Gold and SYBR Orange, the PCR products were analyzed by CE-LIF and MCE-LIF, respectively. Under the optimal conditions, the detection of PCR products of the target bacteria was achieved in less than 15 min by CE-LIF and within 6 min by MCE-LIF. Results: The alignment analysis demonstrated that the PCR products had good agreement with the sequences published in GenBank. The CE-LIF method could detect 10 CFU/mL Y. enterocolitica and L. monocytogenes, and the MCE-LIF method could detect 100 CFU/mL Y. enterocolitica and L. monocytogenes. The intraday precisions of migration time and peak area of DNA markers and PCR products were in the range of 1.13 to 1.18% and 1.60 to 6.29%, respectively, for CE-LIF and 1.18 to 1.48% and 2.85 to 4.06%, respectively, for MCE-LIF. Conclusions: The proposed methods could be applied to target bacterial detection infood samples rapidly, sensitively, and specifically. Highlights: Two new methods based on CE and MCE have been developed for the simultaneous detection of Y. enterocolitica and L. monocytogenes in foodstuffs, and they can detect the bacteria directly without any enrichment because of their high sensitivity.

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31

Berg, Christopher, David C. Valdez, Phillip Bergeron, Maria F. Mora, Carlos D. Garcia, and Arturo Ayon. "Lab-on-a-robot: Integrated microchip CE, power supply, electrochemical detector, wireless unit, and mobile platform." ELECTROPHORESIS 29, no. 24 (December 2008): 4914–21. http://dx.doi.org/10.1002/elps.200800215.

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32

Nogami, Takahiro, Masahiko Hashimoto, and Kazuhiko Tsukagoshi. "Metal ion analysis using microchip CE with chemiluminescence detection based on 1,10-phenanthroline-hydrogen peroxide reaction." Journal of Separation Science 32, no. 3 (February 2009): 408–12. http://dx.doi.org/10.1002/jssc.200800448.

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33

Gong, Maojun, Kenneth R. Wehmeyer, Patrick A. Limbach, and William R. Heineman. "Frontal analysis in microchip CE: A simple and accurate method for determination of protein–DNA dissociation constant." ELECTROPHORESIS 28, no. 5 (March 2007): 837–42. http://dx.doi.org/10.1002/elps.200600398.

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34

He, Qiao-Hong, Qun Fang, Wen-Bin Du, and Zhao-Lun Fang. "Fabrication of a monolithic sampling probe system for automated and continuous sample introduction in microchip-based CE." ELECTROPHORESIS 28, no. 16 (August 2007): 2912–19. http://dx.doi.org/10.1002/elps.200600611.

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35

Ávila, Mónica, María Cristina González, Mohammed Zougagh, Alberto Escarpa, and Ángel Ríos. "Rapid sample screening method for authenticity controlling vanilla flavors using a CE microchip approach with electrochemical detection." ELECTROPHORESIS 28, no. 22 (November 2007): 4233–39. http://dx.doi.org/10.1002/elps.200700277.

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36

Wan, Fen, Weidong He, Jun Zhang, and Benjamin Chu. "Reduced matrix viscosity in DNA sequencing by CE and microchip electrophoresis using a novel thermo-responsive copolymer." ELECTROPHORESIS 30, no. 14 (July 28, 2009): 2488–98. http://dx.doi.org/10.1002/elps.200800773.

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37

Yu, Ming, Hsiang-Yu Wang, and Adam T. Woolley. "Polymer microchip CE of proteins either off- or on-chip labeled with chameleon dye for simplified analysis." ELECTROPHORESIS 30, no. 24 (December 2009): 4230–36. http://dx.doi.org/10.1002/elps.200900349.

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38

Wang, Yineng, Walter Messina, Xi Cao, Anna Hogan, Ed van Zalen, and Eric Moore. "A novel CE microchip with micro pillars column & double-L injection design for Capacitance Coupled Contactless Conductivity detection technology." Journal of Physics: Conference Series 757 (October 2016): 012042. http://dx.doi.org/10.1088/1742-6596/757/1/012042.

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39

Qiao, Juan, Li Qi, Huijuan Yan, Yaping Li, and Xiaoyu Mu. "Microchip CE-LIF method for the hydrolysis of L-glutamine by using L-asparaginase enzyme reactor based on gold nanoparticle." ELECTROPHORESIS 34, no. 3 (January 3, 2013): 409–16. http://dx.doi.org/10.1002/elps.201200461.

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40

Qiu, Jian-Ding, Li Wang, Ru-Ping Liang, and Jing-Wu Wang. "Microchip CE analysis of amino acids on a titanium dioxide nanoparticles-coated PDMS microfluidic device with in-channel indirect amperometric detection." ELECTROPHORESIS 30, no. 19 (October 2009): 3472–79. http://dx.doi.org/10.1002/elps.200900037.

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41

Wang, Hua, Chongxu Han, Huimin Wang, Qinghui Jin, Daxin Wang, Li Cao, and Guangzhou Wang. "Simultaneous Determination of High-Density Lipoprotein, Very Low-Density Lipoprotein and Low-Density Lipoprotein Subclass in Human Serum by Microchip CE." Chromatographia 74, no. 11-12 (September 17, 2011): 799–805. http://dx.doi.org/10.1007/s10337-011-2147-7.

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42

Ni, Yi, Yubin Zhao, Qinmiao Chen, Yoshinori Yamaguchi, and Xiaoming Dou. "Study of the peak broadening due to detection in the electrophoretic separation of DNA by CE and microchip CE and the application of image sensor for ultra‐small detection cell length." Journal of Separation Science 42, no. 13 (May 17, 2019): 2280–88. http://dx.doi.org/10.1002/jssc.201900051.

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43

Okada, Hiroki, Noritada Kaji, Manabu Tokeshi, and Yoshinobu Baba. "Channel wall coating on a poly-(methyl methacrylate) CE microchip by thermal immobilization of a cellulose derivative for size-based protein separation." ELECTROPHORESIS 28, no. 24 (December 2007): 4582–89. http://dx.doi.org/10.1002/elps.200700105.

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44

Pumera, Martin, Arben Merkoçi, and Salvador Alegret. "Carbon nanotube detectors for microchip CE: Comparative study of single-wall and multiwall carbon nanotube, and graphite powder films on glassy carbon, gold, and platinum electrode surfaces." ELECTROPHORESIS 28, no. 8 (April 2007): 1274–80. http://dx.doi.org/10.1002/elps.200600632.

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45

Castaño‐Álvarez, Mario, M. Teresa Fernández‐Abedul, and Agustín Costa‐García. "Analytical Performance of CE Microchips with Amperometric Detection." Instrumentation Science & Technology 34, no. 6 (December 2006): 697–710. http://dx.doi.org/10.1080/10739140600964069.

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46

Escarpa, Alberto, María Cristina González, Agustín González Crevillén, and Antonio Javier Blasco. "CE microchips: An opened gate to food analysis." ELECTROPHORESIS 28, no. 6 (March 2007): 1002–11. http://dx.doi.org/10.1002/elps.200600412.

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47

Chen, Yun, Haotian Duan, Luyan Zhang, and Gang Chen. "Fabrication of PMMA CE microchips by infrared-assisted polymerization." ELECTROPHORESIS 29, no. 24 (December 2008): 4922–27. http://dx.doi.org/10.1002/elps.200800093.

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Escarpa, Alberto, María Cristina González, Miguel Angel López Gil, Agustín G. Crevillén, Miriam Hervás, and Miguel García. "Microchips for CE: Breakthroughs in real-world food analysis." ELECTROPHORESIS 29, no. 24 (December 2008): 4852–61. http://dx.doi.org/10.1002/elps.200800346.

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Lee, Chia-Yen, C. M. Chen, Guan-Liang Chang, Che-Hsin Lin, and Lung-Ming Fu. "Fabrication and characterization of semicircular detection electrodes for contactless conductivity detector – CE microchips." ELECTROPHORESIS 27, no. 24 (December 2006): 5043–50. http://dx.doi.org/10.1002/elps.200600113.

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Qu, Song, Xiaohong Chen, Di Chen, Penyuan Yang, and Gang Chen. "Poly(methyl methacrylate) CE microchips replicated from poly(dimethylsiloxane) templates for the determination of cations." ELECTROPHORESIS 27, no. 24 (December 2006): 4910–18. http://dx.doi.org/10.1002/elps.200600239.

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