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Journal articles on the topic 'Microchip Technology'

Author: Grafiati

Published: 5 June 2025

Last updated: 16 July 2025

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1

Kikutani, Yoshikuni, M. Tokeshi, K. Sato, and Takehiko Kitamori. "Integrated chemical systems on microchips for analysis and assay. Potential future, mobile high-performance detection system for chemical weapons." Pure and Applied Chemistry 74, no. 12 (2002): 2299–309. http://dx.doi.org/10.1351/pac200274122299.

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By analogy to unit operations (e.g., mixers, reactors, etc.) used in conventional chemical engineering, the concept of microunit operations permits the integration of complicated chemical systems onto a small microchip. A protocol for fabrication of such microchips is described, and its use is illustrated in several examples. In addition, the thermal lens microscope, which determines nonfluorescent species at the single-molecule level, is indispensable as an ultrasensitive detector for general use. Applications of microchip technology are given for chemical analysis, immunoassay, and full bioassay. Microchip analysis can provide very large enhancements in sensitivity and substantial reductions in measurement time as compared with conventional analytical methods.

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2

Shekufeh, Shafeie. "Advancing Oral Health and Craniofacial Science through Microchip Implants." Journal of Oral Health and Craniofacial Science 9, no. 1 (2024): 015–18. http://dx.doi.org/10.29328/journal.johcs.1001048.

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Microchip implants have emerged as transformative tools in the realm of oral health and craniofacial science, offering novel solutions to longstanding challenges. This paper aims to explore the diverse applications of microchip technology in dentistry and craniofacial medicine, envisioning a future where these implants play a pivotal role in diagnostics, treatment modalities, and ongoing patient care. The integration of microchips enables real-time monitoring of oral conditions, facilitating early detection of dental issues and providing personalized treatment strategies. Additionally, these implants open avenues for smart prosthetics and orthodontic devices, optimizing patient comfort and treatment outcomes. However, ethical considerations, patient perceptions, and the societal impact of such technology should also be addressed. By examining the multifaceted implications and applications of microchip implants in oral health and craniofacial science, this research overview seeks to contribute valuable insights to the intersection of technology and healthcare in the dental domain.

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3

Nagano, T., Mutsumi Touge, and Junji Watanabe. "Thinning Technology of Patterned Silicon Wafer for Micro Pressure Sensor." Key Engineering Materials 291-292 (August 2005): 419–24. http://dx.doi.org/10.4028/www.scientific.net/kem.291-292.419.

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Recently, the research of the gene using the transgenic mouse has been performed for the development of new medicines. However, 600,000 kinds of mice are produced for the elucidation of each gene function. For this reason, the intelligent microchips have been developed to obtain an individual identification and biological information. The ventricular rate of a mouse can be monitored by the micro pressure sensor mounted on the intelligent microchip. In this research, the detailed structure and functions of the micro pressure sensor were investigated by the FEM analysis, and the sensor-chips were manufactured on 6-inch silicon wafer. The wafer thickness had to be reduced owing to the size restriction of the intelligent microchip. The grinding of the 6-inch silicon wafer with 560 µm in thickness with 19200 sensor-chips was carried out by the newly developed thinning technology. After the basic characteristics of a sensor-chip were evaluated, the output profile containing small peaks corresponding to the heartbeat of a transgenic mouse was finally detected using a mounted sensor-chip.

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4

Ferrara, Massimiliano, and Celeste Ciccia. "Extended market games in technology sectors: microchip manufacturing case study." Applied Mathematical Sciences 19, no. 2 (2025): 93–105. https://doi.org/10.12988/ams.2025.919208.

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This paper extends previous research on one-commodity market games by applying the cooperative approach to technology-intensive sectors, with a specific focus on the microchip manufacturing industry. We introduce two new theoretical results that enhance our understanding of price stability in oligopolistic markets characterized by high entry barriers and substantial R\&D investments. First, we establish the existence of a modified pseudo-core under weakened assumptions about demand elasticity. Second, we demonstrate the convergence of coalition-based pricing strategies in dynamic market conditions. These theoretical advances are validated through a case study of the semiconductor industry, where several manufacturers trade standardized microchips while negotiating prices among coalitions. The empirical findings suggest that cooperative game theory provides valuable insights into pricing stability in technology markets, especially during periods of supply chain disruption.

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5

Shafeie, Shekufeh, Beenish Moalla Chaudhry, and Mona Mohamed. "Modeling Subcutaneous Microchip Implant Acceptance in the General Population: A Cross-Sectional Survey about Concerns and Expectations." Informatics 9, no. 1 (2022): 24. http://dx.doi.org/10.3390/informatics9010024.

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Despite the numerous advantages of microchip implants, their adoption remains low in the public sector. We conducted a cross-sectional survey to identify concerns and expectations about microchip implants among potential users. A total of 179 United States adults aged 18–83 years responded to two qualitative questions that were then analyzed using the thematic analysis technique. The identified codes were first categorized and then clustered to generate themes for both concerns and expectations. The prevalence of each theme was calculated across various demographic factors. Concerns were related to data protection, health risks, knowledge, negative affect, ease of use, metaphysical dilemmas, monetary issues, and negative social impact. Expectations included medical and non-medical uses, dismissal of microchips, technical advances, human enhancement, regulations, and affordability. The prevalence of concerns and benefits differed by immigration status and medical conditions. Informed by our findings, we present a modification to the Technology Acceptance Model for predicting public’s behavioral intention to use subcutaneous microchips. We discuss the five newly proposed determinants and seven predictor variables of this model by surveying the literature.

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6

Ianokaeva, Alina. "Representations of Moscow Residents about the Functions of RFID Microchips and the Risks Associated with Their Implantation." Inter 15, no. 3 (2023): 65–79. http://dx.doi.org/10.19181/inter.2023.15.3.4.

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Microchips implanted into the body could be one of the next steps in developing technology that reflects body health indicators, identifies people, and simplifies daily tasks. The COVID-19 pandemic and the vaccination against the virus have brought the phenomenon of microchip implantation to the forefront of media and consciousness. In the article we identify opinions about the functions and risks of RFID microchips based on interviews with Moscow residents (14 in-depth interviews conducted between March and April 2022). According to empirical data, the identification function aids a person in remembering all their documents, while the storage of medical information is genuinely helpful but rarely used in daily life. While carrying out routine tasks does not seem serious to the informants, it also enables them to fully appreciate the value of the microchip. Additionally, it was discovered that while some groups of informants considered health, privacy, and hacking risks to be important, they did not find physical robbery, inequality, or religious issues to be frightening or to be particularly significant.

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7

Santini, John T., Amy C. Richards, Rebecca A. Scheidt, Michael J. Cima, and Robert S. Langer. "Microchip technology in drug delivery." Annals of Medicine 32, no. 6 (2000): 377–79. http://dx.doi.org/10.3109/07853890008995941.

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8

Kim, Yong Tae. "Development of a Multiplex Colorimetric Genetic Analysis Microchip for Identifying Foodborne Pathogens Using 3D-Printer." ECS Meeting Abstracts MA2024-02, no. 64 (2024): 4292. https://doi.org/10.1149/ma2024-02644292mtgabs.

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The rapid and accurate detection of foodborne pathogens is paramount for safeguarding public health and ensuring the safety of food supplies. In this study, we introduce a groundbreaking approach in the form of a 3D printed multiplex colorimetric genetic analysis microchip tailored specifically for point-of-care analysis of foodborne pathogens. This microchip represents a significant advancement in genetic analysis technology, offering a streamlined and efficient solution for on-site detection. Conventional methods for fabricating genetic analysis chips often involve photolithography, which can be time-consuming, expensive, and technically demanding. In contrast, our microchip is fabricated using stereolithography-digital light processing (SL-DLP) technology, which offers several distinct advantages. SL-DLP is known for its convenience, reproducibility, and cost-effectiveness, making it an ideal choice for the rapid and scalable production of genetic analysis chips. By leveraging this innovative fabrication technique, we have overcome many of the limitations associated with traditional manufacturing methods, paving the way for enhanced accessibility and widespread adoption of genetic analysis technologies. The genetic analysis microchip consists of several key components, each meticulously designed to facilitate efficient and accurate detection of foodborne pathogens. Central to its functionality is the inclusion of a cell sample solution inlet, which allows for the introduction of the sample into the microchip. This inlet is strategically positioned to ensure uniform distribution of the sample throughout the microchip, maximizing the efficiency of the detection process. Additionally, the microchip features four reaction chambers, each dedicated to the isothermal amplification of a different target pathogen. This multiplexing capability enables simultaneous detection of multiple pathogens, greatly enhancing the efficiency and throughput of the analysis process. To further streamline the detection process, the microchip incorporates four loop-mediated isothermal reaction (LAMP) reagent inlets, allowing for the pre-loading of lyophilized reagents into each reaction chamber. This pre-loading step eliminates the need for manual addition of reagents, reducing the risk of contamination and human error. Furthermore, the microchip is fabricated using a photocurable resin composed of poly(ethylene glycol) diacrylate (PEG-DA) (MW=258), which offers several advantages. Notably, this resin enables the printing of high-resolution and transparent structures, facilitating clear observation of color changes indicative of successful gene amplification. To enable colorimetric genetic analysis, Eriochrome Black T (EBT) is added to the LAMP reagent, inducing a distinctive color change upon amplification of the target gene. This colorimetric signal serves as a visual indicator of pathogen presence, allowing for rapid and intuitive interpretation of results. In our experiments, we successfully detected four common foodborne pathogens - Escherichia coli O157:H7, Salmonella enterica, Vibrio parahaemolyticus, and Listeria monocytogenes - within a remarkably short timeframe of 20 minutes. This rapid turnaround time is critical for timely intervention and mitigation of foodborne illness outbreaks. To assess the sensitivity of our microchip, we conducted a limit of detection (LOD) test using samples containing varying concentrations of the target pathogen. Remarkably, we were able to detect as few as 10 cells of the pathogen with a high degree of accuracy, underscoring the sensitivity and reliability of our approach. Furthermore, in multiplex detection tests, each target gene was independently detected within dedicated LAMP chambers, demonstrating the microchip's exceptional specificity and its ability to accurately distinguish between different pathogens. Importantly, the simplicity of fabrication and the readiness for on-site analysis make our microchip highly versatile and adaptable to a wide range of applications beyond food safety. In addition to foodborne pathogen detection, our microchip holds promise for use in clinical diagnosis, forensic analysis, and environmental monitoring. By enabling rapid and accurate genetic analysis in diverse settings, our microchip has the potential to revolutionize the field of molecular diagnostics and significantly improve public health outcomes. In summary, we have developed a novel 3D printed multiplex colorimetric genetic analysis microchip that represents a significant advancement in point-of-care diagnostic technology. By combining state-of-the-art fabrication techniques with innovative design principles, we have created a powerful tool for the rapid and reliable detection of foodborne pathogens. Moving forward, we envision widespread adoption of our microchip as a cornerstone of food safety protocols, facilitating proactive measures to protect consumer health and prevent foodborne illness outbreaks.

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9

Munro, Nicole J., Karen Snow, Jeffrey A. Kant, and James P. Landers. "Molecular Diagnostics on Microfabricated Electrophoretic Devices: From Slab Gel- to Capillary- to Microchip-based Assays for T- and B-Cell Lymphoproliferative Disorders." Clinical Chemistry 45, no. 11 (1999): 1906–17. http://dx.doi.org/10.1093/clinchem/45.11.1906.

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Abstract Background: Current methods for molecular-based diagnosis of disease rely heavily on modern molecular biology techniques for interrogating the genome for aberrant DNA sequences. These techniques typically include amplification of the target DNA sequences followed by separation of the amplified fragments by slab gel electrophoresis. As a result of the labor-intensive, time-consuming nature of slab gel electrophoresis, alternative electrophoretic formats have been developed in the form of capillary electrophoresis and, more recently, multichannel microchip electrophoresis. Methods: Capillary electrophoresis was explored as an alternative to slab gel electrophoresis for the analysis of PCR-amplified products indicative of T- and B-cell malignancies as a means of defining the elements for silica microchip-based diagnosis. Capillary-based separations were replicated on electrophoretic microchips. Results: The microchip-based electrophoretic separation effectively resolved PCR-amplified fragments from the variable region of the T-cell receptor-γ gene (150–250 bp range) and the immunoglobulin heavy chain gene (80–140 bp range), yielding diagnostically relevant information regarding the presence of clonal DNA populations. Although hydroxyethylcellulose provided adequate separation power, the need for a coated microchannel for effective resolution necessitated additional preparative steps. In addition, preliminary data are shown indicating that polyvinylpyrrolidone may provide an adequate matrix without the need for microchannel coating. Conclusions: Separation of B- and T-cell gene rearrangement PCR products on microchips provides diagnostic information in dramatically reduced time (160 s vs 2.5 h) with no loss of diagnostic capacity when compared with current methodologies. As illustrated, this technology and methodology holds great potential for extrapolation to the abundance of similar molecular biology-based techniques.

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10

Nisbet, Nancy. "Resisting Surveillance: Identity and Implantable Microchips." Leonardo 37, no. 3 (2004): 210–14. http://dx.doi.org/10.1162/0024094041139463.

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Surveillance technologies and centralized databases are threatening personal privacy and freedom. Radio Frequency Identification (RFID) microchip technology is one of several potential human tracking and authentication systems. The author's interactive art installation Pop! Goes the Weaselaims to explore opportunities for resisting surveillance by altering underlying assumptions concerning identity. Viewers are encouraged to experiment with resistance by avoiding access control, intervening in the database and subverting notions of a stable or single identity. The author is planning a future project to develop an interface between the author's two implanted microchips and her computer in order to track her computer usage as it relates to her technology-induced shifting sense of self.

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11

Sigworth, F. J., and K. G. Klemic. "Microchip Technology in Ion-Channel Research." IEEE Transactions on Nanobioscience 4, no. 1 (2005): 121–27. http://dx.doi.org/10.1109/tnb.2004.842471.

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12

Amos, Linda. "Movements made visible by microchip technology." Nature 330, no. 6145 (1987): 211–12. http://dx.doi.org/10.1038/330211a0.

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13

Furutani, Shunsuke, Nozomi Furutani, Yasuyuki Kawai, Akifumi Nakayama, and Hidenori Nagai. "Rapid DNA Sequencing Technology Based on the Sanger Method for Bacterial Identification." Sensors 22, no. 6 (2022): 2130. http://dx.doi.org/10.3390/s22062130.

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Antimicrobial resistance, a global health concern, has been increasing due to inappropriate use of antibacterial agents. To facilitate early treatment of sepsis, rapid bacterial identification is imperative to determine appropriate antibacterial agent for better therapeutic outcomes. In this study, we developed a rapid PCR method, rapid cycle sequencing, and microchip electrophoresis, which are the three elemental technologies for DNA sequencing based on the Sanger sequencing method, for bacterial identification. We achieved PCR amplification within 13 min and cycle sequencing within 14 min using a rapid thermal cycle system applying microfluidic technology. Furthermore, DNA analysis was completed in 14 min by constructing an algorithm for analyzing and performing microchip electrophoresis. Thus, the three elemental Sanger-based DNA sequencing steps were accomplished within 41 min. Development of a rapid purification process subsequent to PCR and cycle sequence using a microchip would help realize the identification of causative bacterial agents within one hour, and facilitate early treatment of sepsis.

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14

Park, Myeongho, Bin Yoo, Myeonghwan Hong, et al. "Optimizing Binding Site Spacing in Fluidic Self-Assembly for Enhanced Microchip Integration Density." Micromachines 15, no. 3 (2024): 300. http://dx.doi.org/10.3390/mi15030300.

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This manuscript presents a comprehensive study on the assembly of microchips using fluidic self-assembly (FSA) technology, with a focus on optimizing the spacing between binding sites to improve yield and assembly. Through a series of experiments, we explored the assembly of microchips on substrates with varying binding site spacings, revealing the impact of spacing on the rate of undesired chip assembly across multiple sites. Our findings indicate a significant reduction in incorrect assembly rates as the spacing increases beyond a critical threshold of 140 μm. This study delves into the mechanics of chip alignment within the fluid medium, hypothesizing that the extent of the alloy’s grip on the chips at different spacings influences assembly outcomes. By analyzing cases of undesired assembly, we identified the relationship between binding site spacing and the area of chip contact, demonstrating a decrease in the combined left and right areas of chips as the spacing increases. The results highlight a critical spacing threshold, which, when optimized, could significantly enhance the efficiency and precision of microchip assembly processes using FSA technology. This research contributes to the field of microcomponent assembly, offering insights into achieving higher integration densities and precision in applications, such as microLED displays and augmented reality (AR) devices.

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15

Baba, Yoshinobu. "Genome analysis by microchip and nanochip technology." SEIBUTSU BUTSURI KAGAKU 44, no. 2 (2000): 85–89. http://dx.doi.org/10.2198/sbk.44.85.

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16

Hamilton, Nykoma. "I feel uncomfortable with this microchip technology." Nursing Standard 23, no. 39 (2009): 32. http://dx.doi.org/10.7748/ns.23.39.32.s43.

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17

Gao, Hongjun, and Gradimir Misevic. "Microchip technology applications for blood group analysis." Blood and Genomics 4, no. 2 (2020): 83–95. http://dx.doi.org/10.46701/bg.2020022020109.

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18

Woodward, Sue. "Flaws in the microchip: Technology can fail." British Journal of Neuroscience Nursing 3, no. 10 (2007): 449. http://dx.doi.org/10.12968/bjnn.2007.3.10.27269.

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19

Žnidaršič, Anja, Alenka Baggia, Antonín Pavlíček, Jakub Fischer, Maciej Rostański, and Borut Werber. "Are we Ready to Use Microchip Implants? An International Cross-sectional Study." Organizacija 54, no. 4 (2021): 275–92. http://dx.doi.org/10.2478/orga-2021-0019.

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Abstract Background and purpose: Despite their clear relevance to human life, microchip implants are still widely viewed as negative, threatening our privacy and raising growing concerns about our health. This paper aims to investigate the important factors influencing people’s perception of microchip implants and their willingness to use them for different purposes. Methodology: The cross-sectional study was conducted in three European countries and the data were analysed using the group Structural Equation Modeling approach. Only complete answers to the online survey questionnaire items were used representing a convenience sample of 804 respondents. Results: The results show that perceived ease of use, usefulness and perceived trust are significant predictors of intention to use microchip implants. Perceived trust is influenced by privacy and technology safety. Concerns about painful procedures and other health concerns reduce the perceived usefulness of microchip implants. Apart from the predictor health concerns, the results were similar in all countries. Conclusion: Based on the presented results, researchers interested in investigating the actual use of microchip implants can establish a solid foundation for their research. The results may assist policy makers in developing the regulations to ensure the safe use of microchip implants and allow for a higher level of security. As a follow-up, investigation of changes in the acceptance of microchip implants following the threat of a global pandemic is proposed.

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Zhai, Wenyu. "Enhancing Microchip Performance Through Graphene Integration: A Comparative Analysis with Silicon." Highlights in Science, Engineering and Technology 125 (February 18, 2025): 428–33. https://doi.org/10.54097/adz9h642.

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This paper explores the transformative potential of graphene for microchip technology, emphasizing its superior electrical and thermal properties compared to traditional silicon. Graphene, a two-dimensional material composed of a single layer of carbon atoms, boasts high electron mobility, exceptional thermal conductivity, and robust chemical stability, making it a promising candidate for next-generation microchip applications. This study provides a detailed examination of graphene's characteristics, including its electronic properties and thermal behavior, and discusses the implications of its ultra-high conductivity for microchip efficiency. The comparative analysis highlights the advantages of graphene over silicon in terms of conductivity, thermal properties, and stability, presenting a case for graphene's integration into microchip manufacturing. Despite current production challenges, such as the costliness of graphene synthesis methods like mechanical exfoliation and chemical vapor deposition, the paper argues for the future potential of graphene-based chips. This investigation not only underscores graphene’s capacity to lower threshold currents and enhance microchip efficiency but also addresses the ongoing need for technological advancements in heat dissipation as chip integration and power density increase.

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21

Mecker, Laura C., and R. Scott Martin. "Coupling Microdialysis Sampling to Microchip Electrophoresis in a Reversibly Sealed Device." JALA: Journal of the Association for Laboratory Automation 12, no. 5 (2007): 296–302. http://dx.doi.org/10.1016/j.jala.2007.04.008.

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In this article, we describe the fabrication and characterization of a reversibly sealed microchip device that is used to couple microdialysis sampling to microchip electrophoresis. The ability to interface microdialysis sampling and microchip electrophoresis in a device that is amenable to reversible sealing is advantageous from a repeated use standpoint. Commercially, available tubing coming from the microdialysis probe is directly inserted into the chip and flow from the probe is interfaced to the electrophoresis portion of the device through integrated pneumatic valves. Fluorescence detection was used to characterize the poly(dimethylsiloxane)-based device in terms of injection reproducibility. It was found that the entire system (microdialysis probe and microchip device) has a concentration response lag time of 170 s. Microdialysis sampling followed by an electrophoretic separation of amino acids derivatized with naphthalene-2,3-dicarboxaldehyde/cyanide was also demonstrated.

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22

Shariza, S., T. Joseph Sahaya Anand, A. R. M. Warikh, Lee Cher Chia, Chua Kok Yau, and Lim Boon Huat. "Bond strength evaluation of heat treated Cu-Al wire bonding." Journal of Mechanical Engineering and Sciences 12, no. 4 (2018): 4275–84. http://dx.doi.org/10.15282/jmes.12.4.2018.21.0367.

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Bond strength evaluation of wire bonding in microchips is the key study in any wire bonding mechanism. The quality of the wire bond interconnection relates very closely to the reliability of the microchip during performance of its function in any application. In many reports, concerns regarding the reliability of the microchip are raised due to formation of void at the wire-bond pad bonding interface, predominantly after high temperature storage (HTS) annealing conditions. In this report, the quality of wire bonds prepared at different conditions, specifically annealed at different HTS durations are determined by measurements of the strength of the interface between the bond wire and the bond pad. The samples are tested in pull test and bond shear test. It was observed that the higher bonding temperature as well as the longer duration of HTS increased the bond strength. This is represented through the analysis of the measurements of ball shear strength. This is due to the fact that higher bonding temperature and longer HTS promoted better growth of the Cu-Al IMC layer. A transmission electron microscopy - energy dispersive X-ray analysis (TEM-EDX) has been carried out to observe the formation of the Cu-Al IMC layer in the sample.

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23

Wang, Ke, Peng Zhu, Cong Xu, Qiu Zhang, Zhi Yang, and Ruiqi Shen. "Firing Performance of Microchip Exploding Foil Initiator Triggered by Metal-Oxide-Semiconductor Controlled Thyristor." Micromachines 11, no. 6 (2020): 550. http://dx.doi.org/10.3390/mi11060550.

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In this paper, microchip exploding foil initiators were fabricated by micro-electro-mechanical system scale fabrication methods, such as magnetron sputtering, photolithography, and chemical vapor deposition. A small-scale capacitor discharge unit based on the metal-oxide-semiconductor controlled thyristor was designed and produced to study the performance of the microchip exploding foil initiator. The discharge performance of the capacitor discharge unit without load and the effect of protection devices on the metal-oxide-semiconductor controlled thyristor were studied by the short-circuit discharge test. Then, the electric explosion characteristic of the microchip exploding foil initiator was also conducted to study the circuit current, peak power, deposited energy, and other parameters. Hexanitrostilbene refined by ball-milling and microfluidic technology was adopted to verify the initiation capability of the microchip exploding foil initiator triggered by the metal-oxide-semiconductor controlled thyristor. The results showed that the average inductance and resistance of the capacitor discharge circuit were 22.07 nH and 72.55 mΩ, respectively. The circuit peak current reached 1.96 kA with a rise time of 143.96 ns at 1200 V/0.22 μF. Hexanitrostilbene fabricated by ball-milling and microfluidic technology was successfully initiated at 1200 V/0.22 μF and 1100 V/0.22 μF, respectively.

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24

Edwards, M. C., J. M. Hoy, S. I. FitzGibbon, and P. J. Murray. "Bandicoot bunkers: training wild-caught northern brown bandicoots (Isoodon macrourus) to use microchip-automated safe refuge." Wildlife Research 47, no. 3 (2020): 239. http://dx.doi.org/10.1071/wr19151.

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Abstract ContextSoft-release involving supplementary feeding or shelter is commonly used in wildlife reintroduction and rehabilitation projects. However, competition for nestboxes and supplementary feed, as well as predation at feed stations or nestboxes, can reduce the benefits of soft-release. The use of microchip-automated technology can potentially alleviate these concerns, by providing targeted supplementation to only the intended, microchipped animals. AimsWe aimed to train wild-caught northern brown bandicoots, Isoodon macrourus, to use microchip-automated doors to access safe refuge. MethodsBandicoots were trapped from the wild and brought to the Hidden Vale Wildlife Centre, where eight were trained to use the doors in a six-stage process, and then six were trained in a three-stage process, using a peanut butter reward. Key resultsBandicoots learned to use the doors in as few as 3 days. The duration of visits to the door generally increased during training, although the number of visits decreased. ConclusionsThe bandicoots successfully learned to use the microchip-automated doors, which shows that this technology has great potential with wildlife, particularly given the short training times required. ImplicationsThe use of these microchip-automated doors with wildlife has many potential applications, including supplementary feeding stations, nestboxes, monitoring in the wild, as well as enrichment for wild animals in captivity.

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Powell, Laura, Rodrigo Sergio Wiederkehr, Paige Damascus, et al. "Rapid and sensitive detection of viral nucleic acids using silicon microchips." Analyst 143, no. 11 (2018): 2596–603. http://dx.doi.org/10.1039/c8an00552d.

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26

Mooradian, Aram, Kevin Wall, and James Keszenheimer. "MICROCHIP LASERS AND LASER ARRAYS: TECHNOLOGY AND APPLICATIONS." Optics and Photonics News 6, no. 11 (1995): 16. http://dx.doi.org/10.1364/opn.6.11.000016.

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27

Kuznetsova, V. E., T. A. Luk’yanova, V. A. Vasiliskov, O. V. Kharitonova, A. V. Chudinov, and A. S. Zasedatelev. "Water-soluble cyanine dyes for biological microchip technology." Russian Chemical Bulletin 56, no. 12 (2007): 2438–42. http://dx.doi.org/10.1007/s11172-007-0387-3.

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28

Funaki, Hideyuki, Kazuhiko Itaya, Hiroshi Yamada, Yutaka Onozuka, and Atsuko Iida. "MEMS-LSI Integrated Microchip using Pseudo-SoC Technology." IEEJ Transactions on Sensors and Micromachines 130, no. 5 (2010): 194–200. http://dx.doi.org/10.1541/ieejsmas.130.194.

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Kuznetsova, V. E., V. A. Vasiliskov, O. V. Antonova, V. M. Mikhailovich, A. S. Zasedatelev, and A. V. Chudinov. "New indodicarbocyanine dyes for the biological microchip technology." Russian Journal of Bioorganic Chemistry 34, no. 1 (2008): 130–33. http://dx.doi.org/10.1134/s1068162008010184.

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30

Satheesh, Nitesh. "Medium-Voltage Silicon Carbide Solution for Rail." Electric and Hybrid Rail Technology 2024 (January 2024): 33–34. http://dx.doi.org/10.12968/s2754-7760(24)70011-5.

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31

Wysoczański, Bartłomiej, Marcin Świątek, and Anna Wójcik-Gładysz. "Organ-on-a-Chip Models—New Possibilities in Experimental Science and Disease Modeling." Biomolecules 14, no. 12 (2024): 1569. https://doi.org/10.3390/biom14121569.

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‘Organ-on-a-chip’ technology is a promising and rapidly evolving model in biological research. This innovative microfluidic cell culture device was created using a microchip with continuously perfused chambers, populated by living cells arranged to replicate physiological processes at the tissue and organ levels. By consolidating multicellular structures, tissue–tissue interfaces, and physicochemical microenvironments, these microchips can replicate key organ functions. They also enable the high-resolution, real-time imaging and analysis of the biochemical, genetic, and metabolic activities of living cells in the functional tissue and organ contexts. This technology can accelerate research into tissue development, organ physiology and disease etiology, therapeutic approaches, and drug testing. It enables the replication of entire organ functions (e.g., liver-on-a-chip, hypothalamus–pituitary-on-a-chip) or the creation of disease models (e.g., amyotrophic lateral sclerosis-on-a-chip, Parkinson’s disease-on-a-chip) using specialized microchips and combining them into an integrated functional system. This technology allows for a significant reduction in the number of animals used in experiments, high reproducibility of results, and the possibility of simultaneous use of multiple cell types in a single model. However, its application requires specialized equipment, advanced expertise, and currently incurs high costs. Additionally, achieving the level of standardization needed for commercialization remains a challenge at this stage of development.

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K., Balaji, Kostecki Miroslav, and Senthil Kumar P. "FOSTERING INNOVATIONS IN PERVASIVE APPLICATIONS THROUGH TEACHING & LEARNING OF STEMSEL MICROCHIP TECHNOLOGY." International Journal of Computational Research and Development 1, no. 2 (2017): 41–43. https://doi.org/10.5281/zenodo.437985.

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This Paper describes the new Paradigm in the Teaching & Learning of Embedded & Microcontroller programming and Application Development. The Authors use the STEMSEL Microchip Programming methodology to teach the Application Development for Pervasive Computing Environments. In the recent years the development of Applications in Ubiquitous environments with the use Internet of Things has triggered a massive research challenges and intensive programming needs. This paper explains the use of a new Integrated Development Environment using simple Graphical Drag & Drop based tool to program such applications. This is applied to develop applications using Bluetooth, WIFI etc for various pervasive computing needs. This Integrated Development Environment is very useful to teach & learn such technologies in a simple and quick way. In this paper, it is shown that the use of STEMSEL Microchip technology in Teaching, Learning, and Development of Pervasive Applications will reduce Learning Time & Time to Market the Applications.

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Norman, Helen. "Put to the Test." Electric and Hybrid Rail Technology 2021, no. 2 (2022): 17. http://dx.doi.org/10.12968/s2754-7760(23)70060-1.

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Nayak, Ananya, Dipankar Chatterjee, and Suvarun Dalapati. "An Experimental Set-up Involving Low-cost Digital Controller to Study the Magnetizing Inrush Current in a Transformer using Point-on-Wave Switching Technique." Power Electronics and Drives 9, no. 1 (2024): 292–316. http://dx.doi.org/10.2478/pead-2024-0019.

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Abstract Generally in under-graduate studies, magnetizing inrush current (MIC) is discussed theoretically without giving much practical exposure. This paper presents the development of a low cost experimental set-up using a digital controller to study the MIC and the different parameters which can affect the same. This also helps to show how the inrush current can be minimized. This set-up also provides a hands-on experience of MIC and its control in under-graduate study, which can help an upcoming practitioner in industry as well as in further research. This paper presents a brief description of MIC, followed by a short analysis. Here, a pair of anti-parallel thyristors are connected in series with the primary winding of a single-phase power transformer. The turningon instant of this switch, with respect to the zero-crossing instant of the input supply voltage, may be adjusted through a firmware, in a PIC18F4620 from Microchip Technology microcontroller development board from Microchip Technology to control the transformer energisation instant. The firmware is developed in MPLABX-IDE from Microchip Technology, and the scheme is verified via simulations in Proteus simulation software. A suitable circuit to support the microcontroller development board to achieve the above function is designed and fabricated.

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Zhang, Xuning, Tomas Krecek, and Nitesh Satheesh. "Beyond the Datasheet." Electric and Hybrid Rail Technology 2021, no. 1 (2021): 54–55. http://dx.doi.org/10.12968/s2754-7760(23)70015-7.

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Microchip Technology reveals the key benefits of silicon carbide (SiC) semiconductors, including improved system efficiency, reduced power electronics costs, and the ability to support higher operating temperatures

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Krecek, Tomas, and Nitesh Satheesh. "Switched On." Electric and Hybrid Rail Technology 2021, no. 2 (2022): 54–55. http://dx.doi.org/10.12968/s2754-7760(23)70071-6.

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Lee, Ji Hye, June Moon Jang, Han Sang Cho, et al. "Design and Characterization of Microfluidic Analysis System for RNA-Aminoglycoside Interactions." Key Engineering Materials 277-279 (January 2005): 90–95. http://dx.doi.org/10.4028/www.scientific.net/kem.277-279.90.

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Microfluidic devices are of considerable interest, since such technology offers great promise for the development of powerful and versatile miniaturized analyzers. Accordingly, the present work describes a microfluidic screening system that is composed of a microchip, hydrodynamic pumping unit and fluorescence detectors. To develop an assay for RNA-aminoglycoside interactions, microchips are designed and fabricated on a glass substrate, then flow simulations are performed in the microchannels. After optimizing the flow control and buffer composition for fluorescence-based biochemical assays, a fluorescently labeled aminoglycoside probe and RNA are allowed to flow continuously to the main micro-channel based on hydrodynamic pumping and their interactions monitored by fluorescence quenching, which is reversed upon competition with other aminoglycosides. Consequently, the proposed device can serve as an integrated microfluidic platform for the high-throughput screening of high affinity antibiotics for RNA targets.

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Li, Hai Feng, and Wei Rong Zhao. "Greenhouse Enviroment Monitoring System Based on Zigbee Technology." Applied Mechanics and Materials 727-728 (January 2015): 666–69. http://dx.doi.org/10.4028/www.scientific.net/amm.727-728.666.

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A sensor network is issued in this paper, which is used to monitor the enviroment parameters of greenhouse. Each sensor node of the system, which is composed of sensors and a microchip, could measure temperature, humidity, pH value of soil, air pressure etc. A GPRS module is used to complete data exchanging between remote monitoring platform and the wireless sensor network. This system is an application in agriculture field.

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Shen, Peijun. "The development history and future trends of the microchip." Applied and Computational Engineering 22, no. 1 (2023): 88–94. http://dx.doi.org/10.54254/2755-2721/22/20231174.

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This essay provides a detailed analysis of the evolution of microchip technology from its inception to its prospects. It starts by discussing the foundational work of pioneers like Jack Kilby and Robert Noyce and the transformative effect of Moore's Law on chip design and manufacturing. It then evaluates the current state of chip technology, including the leading industry players and challenges such as chip shortages and trade disputes. The essay then explores the anticipated trends in chip technology, such as quantum computing and innovative materials like graphene. It concludes by assessing the expected influence of these advancements on various sectors, including Artificial Intelligence (AI), the Internet of Things (IoT), and autonomous vehicles, and their broader social, economic, and environmental implications. This essay presents a comprehensive and thoughtful analysis of microchip technology's past, present, and future and its far-reaching impact on modern society.

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Norman, Helen. "Knowledge is Power." Electric and Hybrid Rail Technology 2023, no. 1 (2023): 36–40. http://dx.doi.org/10.12968/s2754-7760(23)70108-4.

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Experts from two firms leading the way in developing new silicon carbide power modules for traction, Mitsubishi Electric and Microchip Technology, reveal how SiC technology can help rail operators reduce energy losses and improve reliability and efficiency, while minimizing their impact on the environment

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Brüggemann, Andrea, Sonja Stoelzle, Michael George, Jan C Behrends, and Niels Fertig. "Microchip Technology for Automated and Parallel Patch-Clamp Recording." Small 2, no. 7 (2006): 840–46. http://dx.doi.org/10.1002/smll.200600083.

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Georgoutsou-Spyridonos, Maria, Myrto Filippidou, Georgia D. Kaprou, Dimitrios C. Mastellos, Stavros Chatzandroulis, and Angeliki Tserepi. "Isothermal Recombinase Polymerase Amplification (RPA) of E. coli gDNA in Commercially Fabricated PCB-Based Microfluidic Platforms." Micromachines 12, no. 11 (2021): 1387. http://dx.doi.org/10.3390/mi12111387.

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Printed circuit board (PCB) technology has been recently proposed as a convenient platform for seamlessly integrating electronics and microfluidics in the same substrate, thus facilitating the introduction of integrated and low-cost microfluidic devices to the market, thanks to the inherent upscaling potential of the PCB industry. Herein, a microfluidic chip, encompassing on PCB both a meandering microchannel and microheaters to accommodate recombinase polymerase amplification (RPA), is designed and commercially fabricated for the first time on PCB. The developed microchip is validated for RPA-based amplification of two E. coli target genes compared to a conventional thermocycler. The RPA performance of the PCB microchip was found to be well-comparable to that of a thermocycler yet with a remarkably lower power consumption (0.6 W). This microchip is intended for seamless integration with biosensors in the same PCB substrate for the development of a point-of-care (POC) molecular diagnostics platform.

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Martens, Julien, Calogero Gueli, Max Eickenscheidt, and Thomas Stieglitz. "Microchip Transfer Process for Implantable Flexible Bioelectronic Devices." Current Directions in Biomedical Engineering 7, no. 2 (2021): 41–44. http://dx.doi.org/10.1515/cdbme-2021-2011.

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Abstract The demands on flexible implants for recording of neural signals and electrical stimulating have increased in recent years with regard to their functionality, miniaturization, and spatial resolution. These requirements can be met best by embedding powerful complementary metal oxide semiconductor (CMOS) microchips into thin biocompatible polymer substrates. So-called chip-in-foil systems thus combine mechanical properties of a polymer substrate and performance of CMOS technology. The development of a process for direct transfer of multiple CMOS microchips (edge length <400 μm) simultaneously into thin polyimide (PI) substrates is subject of this study. It allows the use of standard microelectromechanical systems (MEMS) processes for further levelled superficial layer build-up. This is achieved with the help of a silicon carrier wafer equipped with cavities for precise chip placement and a sacrificial layer to facilitate release of the chip-in-foil systems. In a post-processing step all silicon chips are thinned down to 100 μm. With this process a transfer yield of 100 % (n = 34) was achieved for the silicon chips on a die level. Chip rotational error on substrates was determined to be as low as 0.21° ± 0.10°. Die adhesion was examined by shear tests, resulting in shear strength of 58.1 MPa ± 13.7 MPa, which dropped to 15.2 MPa ± 10.5 MPa after accelerated ageing in 60 °C phosphate buffered saline solution (PBS) for 16 days (equivalent to 78 days at 37 °C). This study demonstrated a reliable microchip transfer process with low positioning error into flexible PI substrates with post-processing thinning of the dies. The use of a carrier silicon wafer allowed precise electrical interconnect fabrication with standard MEMS processing techniques and without handling of thin and fragile chips. These results are a prerequisite to meet needs of reliability and structural biocompatibility in implantable flexible bioelectronic devices.

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Zhang, Xuelin, Yufan Zhou, Ying Chen, Ming Li, Haitao Yu, and Xinxin Li. "Advanced In Situ TEM Microchip with Excellent Temperature Uniformity and High Spatial Resolution." Sensors 23, no. 9 (2023): 4470. http://dx.doi.org/10.3390/s23094470.

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Transmission electron microscopy (TEM) is a highly effective method for scientific research, providing comprehensive analysis and characterization. However, traditional TEM is limited to observing static material structures at room temperature within a high-vacuum environment. To address this limitation, a microchip was developed for in situ TEM characterization, enabling the real-time study of material structure evolution and chemical process mechanisms. This microchip, based on microelectromechanical System (MEMS) technology, is capable of introducing multi-physics stimulation and can be used in conjunction with TEM to investigate the dynamic changes of matter in gas and high-temperature environments. The microchip design ensures a high-temperature uniformity in the sample observation area, and a system of tests was established to verify its performance. Results show that the temperature uniformity of 10 real-time observation windows with a total area of up to 1130 μm2 exceeded 95%, and the spatial resolution reached the lattice level, even in a flowing atmosphere of 1 bar.

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Kustos, Ildikó, Béla Kocsis, and Ferenc Kilár. "Bacterial outer membrane protein analysis by electrophoresis and microchip technology." Expert Review of Proteomics 4, no. 1 (2007): 91–106. http://dx.doi.org/10.1586/14789450.4.1.91.

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Chen, Shaojie, Jicheng Zhang, Dawei Yin, Xianzhen Cheng, and Ning Jiang. "Relative permeability measurement of coal microchannels using advanced microchip technology." Fuel 312 (March 2022): 122633. http://dx.doi.org/10.1016/j.fuel.2021.122633.

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Sato, Kae, Yo Tanaka, Björn Renberg, and Takehiko Kitamori. "Combining microchip and cell technology for creation of novel biodevices." Analytical and Bioanalytical Chemistry 393, no. 1 (2008): 23–29. http://dx.doi.org/10.1007/s00216-008-2450-9.

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SHEN, K., X. CHEN, M. GUO, and J. CHENG. "A microchip-based PCR device using flexible printed circuit technology." Sensors and Actuators B: Chemical 105, no. 2 (2005): 251–58. http://dx.doi.org/10.1016/s0925-4005(04)00432-0.

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Hoy, Julia M., Peter J. Murray, and Andrew Tribe. "The potential for microchip-automated technology to improve enrichment practices." Zoo Biology 29, no. 5 (2009): 586–99. http://dx.doi.org/10.1002/zoo.20296.

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Pugia, Michael J., Gert Blankenstein, Ralf-Peter Peters, et al. "Microfluidic Tool Box as Technology Platform for Hand-Held Diagnostics." Clinical Chemistry 51, no. 10 (2005): 1923–32. http://dx.doi.org/10.1373/clinchem.2005.052498.

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Abstract Background: Use of microfluidics in point-of-care testing (POCT) will require on-board fluidics, self-contained reagents, and multistep reactions, all at a low cost. Disposable microchips were studied as a potential POCT platform. Methods: Micron-sized structures and capillaries were embedded in disposable plastics with mechanisms for fluidic control, metering, specimen application, separation, and mixing of nanoliter to microliter volumes. Designs allowed dry reagents to be on separate substrates and liquid reagents to be added. Control of surface energy to ±5 dyne/cm2 and mechanical tolerances to ≤1 μm were used to control flow propulsion into adsorptive, chromatographic, and capillary zones. Fluidic mechanisms were combined into working examples for urinalysis, blood glucose, and hemoglobin A1c testing using indicators (substances that react with analyte, such as dyes, enzyme substrates, and diazonium salts), catalytic reactions, and antibodies as recognition components. Optical signal generation characterized fluid flow and allowed detection. Results: We produced chips that included capillary geometries from 10 to 200 μm with geometries for stopping and starting the flow of blood, urine, or buffer; vented chambers for metering and splitting 100 nL to 30 μL; specimen inlets for bubble-free specimen entry and containment; capillary manifolds for mixing; microstructure interfaces for homogeneous transfer into separation membranes; miniaturized containers for liquid storage and release; and moisture vapor barrier seals for easy use. Serum was separated from whole blood in &lt;10 s. Miniaturization benefits were obtained at 10–200 μm. Conclusion: Disposable microchip technology is compatible with conventional dry-reagent technology and allows a highly compact system for complex assay sequences with minimum manual manipulations and simple operation.

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