Relevant bibliographies by topics / Microcirculation Animal models

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  1. Journal articles
  2. Dissertations / Theses
  3. Book chapters
  4. Conference papers

Academic literature on the topic 'Microcirculation Animal models'

Author: Grafiati
Published: 4 June 2021
Last updated: 2 February 2022

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Journal articles on the topic "Microcirculation Animal models"

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Kan, Zuxing, Kenneth Wright, and Sidney Wallace. "Ethiodized oil emulsions in hepatic microcirculation: In vivo microscopy in animal models." Academic Radiology 4, no. 4 (1997): 275–82. http://dx.doi.org/10.1016/s1076-6332(97)80029-3.

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Wiernsperger, Nicolas, Pierre Nivoit, and Eliete Bouskela. "Microcirculation in obesity: an unexplored domain." Anais da Academia Brasileira de Ciências 79, no. 4 (2007): 617–38. http://dx.doi.org/10.1590/s0001-37652007000400005.

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Obesity is traditionally linked to diabetes and cardiovascular diseases. Very recent experimental, clinical and epidemiological, sometimes provocative, data challenge this automaticity by showing that not the amount but the distribution of fat is the important determinant. Moderate abdominal fat accumulation may thus be more harmful than even consequent overweight. In view of the worldwide burden of obesity, factors leading to it in children and young adults must urgently be identified. Since obesity is a very complex cardiometabolic situation, this will require to focus investigations on unco
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Padró, Teresa, Gemma Vilahur, and Lina Badimon. "Dyslipidemias and Microcirculation." Current Pharmaceutical Design 24, no. 25 (2018): 2921–26. http://dx.doi.org/10.2174/1381612824666180702154129.

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Dyslipidemia is widely accepted as one of the major risk factors in cardiovascular disease mainly due to its contribution in the pathogenesis of atherosclerosis in medium-sized and large arteries. However, it has become increasingly accepted that high-cholesterol levels can also adversely affect the microvasculature prior to the development of overt atherosclerosis. Moreover, hypercholesterolemia has shown, in preclinical animal models, to exert detrimental effects beyond the vascular tree leading to larger infarcts and adverse cardiac remodeling post-myocardial infarction. At a functional lev
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Chemonges, Saul, Kiran Shekar, John-Paul Tung, et al. "Optimal Management of the Critically Ill: Anaesthesia, Monitoring, Data Capture, and Point-of-Care Technological Practices in Ovine Models of Critical Care." BioMed Research International 2014 (2014): 1–17. http://dx.doi.org/10.1155/2014/468309.

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Animal models of critical illness are vital in biomedical research. They provide possibilities for the investigation of pathophysiological processes that may not otherwise be possible in humans. In order to be clinically applicable, the model should simulate the critical care situation realistically, including anaesthesia, monitoring, sampling, utilising appropriate personnel skill mix, and therapeutic interventions. There are limited data documenting the constitution of ideal technologically advanced large animal critical care practices and all the processes of the animal model. In this paper
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Deng, Yupu, Katelynn J. Rowe, Ketul R. Chaudhary, Anli Yang, Shirley H. J. Mei, and Duncan J. Stewart. "Optimizing imaging of the rat pulmonary microvasculature by micro-computed tomography." Pulmonary Circulation 9, no. 4 (2019): 204589401988361. http://dx.doi.org/10.1177/2045894019883613.

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Micro-computed tomography (micro-CT) is used in pre-clinical research to generate high-resolution three-dimensional (3D) images of organs and tissues. When combined with intravascular contrast agents, micro-CT can provide 3D visualization and quantification of vascular networks in many different organs. However, the lungs present a particular challenge for contrast perfusion due to the complexity and fragile nature of the lung microcirculation. The protocol described here has been optimized to achieve consistent lung perfusion of the microvasculature to vessels < 20 microns in both normal a
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Busek, Mathias, Stefan Gruenzner, Tobias Steege, Florian Schmieder, Udo Klotzbach, and Frank Sonntag. "Design, characterization, and modeling of microcirculation systems with integrated oxygenators." Journal of Sensors and Sensor Systems 5, no. 1 (2016): 221–28. http://dx.doi.org/10.5194/jsss-5-221-2016.

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Abstract. Here, we describe a microfluidic system for hypoxia assays on human cell culture models. These systems are developed to replace or reduce animal testing in biomedical basic research. The presented system uses a gas-permeable membrane as a gas–liquid interface and a micropump for media actuation to influence the oxygen content in two cell culture chambers. To apply well-defined hypoxic conditions to the cells, a good understanding of the mass transport phenomena is necessary. Therefore, a complete network model of the microfluidic system is presented. This model is validated by means
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Lee, Eek-Sung, Jin-Hui Yoon, Jiye Choi, Faris R. Andika, Taekwan Lee, and Yong Jeong. "A mouse model of subcortical vascular dementia reflecting degeneration of cerebral white matter and microcirculation." Journal of Cerebral Blood Flow & Metabolism 39, no. 1 (2017): 44–57. http://dx.doi.org/10.1177/0271678x17736963.

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Subcortical vascular dementia(SVaD) is associated with white matter damage, lacunar infarction, and degeneration of cerebral microcirculation. Currently available mouse models can mimic only partial aspects of human SVaD features. Here, we combined bilateral common carotid artery stenosis (BCAS) with a hyperlipidaemia model in order to develop a mouse model of SVaD; 10- to 12-week-old apolipoprotein E (ApoE)-deficient or wild-type C57BL/6J mice were subjected to sham operation or chronic cerebral hypoperfusion with BCAS using micro-coils. Behavioural performance (locomotion, spatial working me
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Nakase, Hiroyuki, Oliver S. Kempski, Axel Heimann, Toshikazu Takeshima, and Jaroslav Tintera. "Microcirculation after cerebral venous occlusions as assessed by laser Doppler scanning." Journal of Neurosurgery 87, no. 2 (1997): 307–14. http://dx.doi.org/10.3171/jns.1997.87.2.0307.

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✓ Research on cerebral venous circulation disturbances (CVCDs) has been limited partly by the paucity of animal models that produce consistent venous infarction. Occlusion of two adjacent cortical veins in rats by means of a photochemical thrombotic technique provides a minimally invasive, clinically relevant, and reproducible model suited to study the pathophysiology of CVCDs. In this study, the effects of venous occlusion on regional cortical blood flow and the brain damage that ensues were evaluated. Cortical vein occlusion was induced by photoactivation of rose bengal via 100-µm fiberoptic
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Stepp, David W., David M. Pollock, and Jefferson C. Frisbee. "Low-flow vascular remodeling in the metabolic syndrome X." American Journal of Physiology-Heart and Circulatory Physiology 286, no. 3 (2004): H964—H970. http://dx.doi.org/10.1152/ajpheart.00836.2003.

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Peripheral microvascular dysfunction is a common affliction in patients with the metabolic syndrome X. Previous studies have described a number of vascular impairments in vasomotor control in both human patients and animal models of syndrome X, but the net effect of these impairments on microvascular structure has not been examined. The goal of the current study was to test the hypothesis that syndrome X reduces muscle perfusion and induces vascular remodeling. The obese Zucker rat was used as a model of syndrome X, and the microcirculation of the hindlimb and brain were examined. Obese Zucker
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Ince, Can, and Egbert G. Mik. "Microcirculatory and mitochondrial hypoxia in sepsis, shock, and resuscitation." Journal of Applied Physiology 120, no. 2 (2016): 226–35. http://dx.doi.org/10.1152/japplphysiol.00298.2015.

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After shock, persistent oxygen extraction deficit despite the apparent adequate recovery of systemic hemodynamic and oxygen-derived variables has been a source of uncertainty and controversy. Dysfunction of oxygen transport pathways during intensive care underlies the sequelae that lead to organ failure, and the limitations of techniques used to measure tissue oxygenation in vivo have contributed to the lack of progress in this area. Novel techniques have provided detailed quantitative insight into the determinants of microcirculatory and mitochondrial oxygenation. These techniques, which are
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Dissertations / Theses on the topic "Microcirculation Animal models"

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Fournet, Gabrielle. "IVIM : modeling, experimental validation and application to animal models." Thesis, Université Paris-Saclay (ComUE), 2016. http://www.theses.fr/2016SACLS367/document.

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Cette thèse porte sur l’étude de la séquence d’imagerie IRM IVIM (« Intravoxel incoherent motion »). Cette séquence permet l’étude des microvaisseaux sanguins tels que les capillaires, artérioles et veinules. Pour être sensible seulement aux groupes de spins non statiques dans les tissus, des gradients de diffusion sont ajoutés avant et après l’impulsion 180° d’une séquence d’écho de spin. La composante du signal correspondant aux spins qui diffusent dans le tissu peut être séparée de celle des spins en mouvement dans les vaisseaux sanguins qui est appelée signal IVIM. Ces deux composantes son
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Tao, Lian. "The blood-testis barrier and blood vessel permeability in rat testis." Title page, contents and abstract only, 1994. http://web4.library.adelaide.edu.au/theses/09PH/09pht1712.pdf.

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Bibliography: leaves 150-183. Considers the tubule and capillary barriers from the point of view of anatomy, physiological function and possible factors which may cause the tubule barrier to be breached or influence substance exchange across the capillary wall.
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Bazin, Jean-Étienne. "Influence de l'anesthesie sur l'interpretation des resultats des modeles experimentaux animaux." Clermont-Ferrand 1, 1999. http://www.theses.fr/1999CLF1MM14.

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Boa, Beatriz Costa da Silva. "Efeitos de modificação dietética associada ou não a uma rotina de exercícios aeróbicos na microcirculação em modelo animal de obesidade exógena." Universidade do Estado do Rio de Janeiro, 2012. http://www.bdtd.uerj.br/tde_busca/arquivo.php?codArquivo=8040.

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Coordenação de Aperfeiçoamento de Pessoal de Nível Superior<br>A obesidade atinge proporções epidêmicas em países industrializados e está relacionada a uma série de doenças metabólicas e circulatórias. Nesse contexto, a atividade física, tratamento não farmacológico da obesidade, acessível a diversas populações e está relacionada com a redução do risco cardiovasvascular mesmo. O objetivo deste trabalho foi avaliar, após mudança ou não da dieta, associação ou não a um programa de treinamento aeróbico (PTA) durante 8 semanas, a possível reversibilidade dos danos causados por uma dieta hiperlipíd
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Book chapters on the topic "Microcirculation Animal models"

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Sorop, Oana, Jens van de Wouw, Daphne Merkus, and Dirk J. Duncker. "Coronary Microvascular Dysfunction in Cardiovascular Disease: Lessons from Large Animal Models." In Microcirculation. Springer International Publishing, 2019. http://dx.doi.org/10.1007/978-3-030-28199-1_2.

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Nalbantoglu, Ufuk. "Microcirculation Model for Invasive Animal Monitoring." In Plastic and Reconstructive Surgery. Springer London, 2014. http://dx.doi.org/10.1007/978-1-4471-6335-0_14.

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Ryoiti, Eduardo, Priscila Aikawa, Jose Jukemura, Paulina Sannomiya, and Naomi Kondo. "An Animal Model of Sepsis in Appendicitis: Assessment of the Microcirculation." In Appendicitis - A Collection of Essays from Around the World. InTech, 2012. http://dx.doi.org/10.5772/26642.

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Conference papers on the topic "Microcirculation Animal models"

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Funamoto, Kenichi, Toshiyuki Hayase, and Tetsuya Kodama. "Visualization of Microcirculation Based on Brightness Variation in Contrast-Enhanced Ultrasound." In ASME 2010 Summer Bioengineering Conference. American Society of Mechanical Engineers, 2010. http://dx.doi.org/10.1115/sbc2010-19349.

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Many studies have investigated effects of drug administration and gene transfer to treat tumors in small animal models. Microcirculation plays important roles in the development and growth of tissues; a tumor proliferates by angiogenesis [1], resulting in the formation of a dense microvasculature, while the microvasculature degenerates in locations where necrosis or apoptosis occurs. Hence, the growth of a tumor can be evaluated based on comprehension of the morphology of microcirculation. Enhanced visualizations of small blood vessels enabled by microbubbles or contrast agent have been report
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Journal articles
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