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Journal articles on the topic 'Microcirculatory vessels'

Author: Grafiati

Published: 2 June 2025

Last updated: 31 July 2025

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1

Stegney, Zh. "Морфологічні особливості кровоносних судин тимуса новонароджених телят". Scientific Messenger of LNU of Veterinary Medicine and Biotechnologies 19, № 82 (2017): 12–15. http://dx.doi.org/10.15421/nvlvet8203.

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The blood vessels of thymus of newborn calves were studied by using a complex of histological methods and methods of injection of blood vessels. Calf thymus gland is an unpaired organ consisting of a pair of cervical, unpaired cervical and thoracic lobes. Radiating insertions (septa) extrude from the capsule, dividing organ on lobules. Stroma (6.53 ± 2.33%) consists of loose connective tissue. The base of the lobules is formed by a lymphoid tissue (epithelial with cells of the lymphoid series). The area of the parenchyma of the diurnal calves’ thymus is 80.57 ± 3.46%. The thymus lobes consist

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Di Dedda, Umberto, Alice Ascari, Angela Fantinato, Dario Fina, Ekaterina Baryshnikova, and Marco Ranucci. "Microcirculatory Alterations in Critically Ill Patients with COVID-19-Associated Acute Respiratory Distress Syndrome." Journal of Clinical Medicine 11, no. 4 (2022): 1032. http://dx.doi.org/10.3390/jcm11041032.

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Background: Presently, a number of specific observations have been performed on microcirculatory function in a coronavirus disease-19 (COVID-19) setting. We hypothesized that, in the critically ill, endothelial dysfunction secondary to severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) infection and the subsequent inflammation and coagulopathy may lead to microcirculatory alterations, further exacerbated by the hypoxemic state. A dysfunctional microcirculation may represent the hidden motor underlying the development of COVID-19’s clinical manifestations. Methods: A single center, pr

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Alba-Alejandre, Irene, Stephan Hiedl, and Orsolya Genzel-Boroviczény. "Microcirculatory Changes in Term Newborns with Suspected Infection: An Observational Prospective Study." International Journal of Pediatrics 2013 (2013): 1–6. http://dx.doi.org/10.1155/2013/768784.

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Background. In adults severely disturbed microcirculatory flow can be observed by Orthogonal Polarized Spectral (OPS) imaging techniques during sepsis. Therefore we set out to assess for microcirculatory changes in term newborns with suspected early onset infection using OPS.Methods. OPS images were obtained prospectively from the vascular bed of the ear conch and upper arm of 47 newborns on their 1st, 2nd, and 3rd day of life. OPS sequences were analyzed semiquantitatively offline and blinded to clinical status of the infant. Flow in vessels was classified as continuous or noncontinuous flow

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Hnatjuk, Mykhailo, Serhii Nesteruk, Liudmyla Tatarchuk, and Nataliia Monastyrska. "Morphometric assessment of age-related structural changes in the vessels of the microcirculatory bed of the prostate gland under conditions of ethanol intoxication." Bulletin Of Medical And Biological Research 17, no. 3 (2023): 8–15. http://dx.doi.org/10.61751/bmbr.2706-6290.2023.3.8.

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Vessels of the microcirculatory bed ensure the full trophism of the body at the level of capillary-tissue relations and are the first to respond to various functional and pathological conditions of organs. At the same time, morphological changes in prostate microvasculature with age under conditions of prolonged ethanol poisoning have been understudied. The purpose of this study was to determine the age-related remodelling of the prostate vessels of the microcirculatory bed in case of prolonged alcohol intoxication. Injection, histological, morphometric, and statistical methods were used. The

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Petrov, S. B. "Quantitative characteristics of the microvasculature of cancer tumors." Kazan medical journal 66, no. 2 (1985): 159. http://dx.doi.org/10.17816/kazmj61213.

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Toth, A., M. E. Tischler, M. Pal, A. Koller, and P. C. Johnson. "A multipurpose instrument for quantitative intravital microscopy." Journal of Applied Physiology 73, no. 1 (1992): 296–306. http://dx.doi.org/10.1152/jappl.1992.73.1.296.

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An in vivo microscope system has been developed that can measure fluorescence emission and/or light absorption at up to five wavelengths in a tissue area of 18–30 microns diam while imaging adjacent microcirculatory vessels with a video system. The system also incorporates a computer-controlled stage and data acquisition system for rapid and repeated measurements from a number of tissue sites. The tissue area monitored for fluorescence or absorption can be defined further by a confocal arrangement of the microscope optics. Tests of the system for NADH fluorescence measurements show good agreem

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Kuznetsova, T. E., E. L. Ryzhkovskaya, and E. I. Kalinovskaya. "STRUCTURAL CHANGES IN THE MICROCIRCULATORY BED OF THE PANCREAS IN RATS WITH EXPERIMENTAL METABOLIC SYNDROME." Proceedings of the National Academy of Sciences of Belarus, Medical series 15, no. 3 (2018): 347–53. http://dx.doi.org/10.29235/1814-6023-2018-15-3-347-353.

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A complex histological, histochemical and electron microscopic study of the state of the microcirculatory bed of the pancreas and conjugate transformations in the parenchyma of the organ after modeling the metabolic syndrome using a diet high in fats and carbohydrates was carried out. Spasm of arterioles, the marginal state of leukocytes and the desquamation of endotheliocytes into the lumen of a vessel, the stasis of erythrocytes in capillaries were revealed. The endothelial cells of capillaries had signs of increased transport of substances through the vessel walls: pinocytosis, fenestration

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Chalkias, Athanasios, Nikolaos Papagiannakis, Georgios Mavrovounis, et al. "Sublingual microcirculatory alterations during the immediate and early postoperative period: A systematic review and meta-analysis." Clinical Hemorheology and Microcirculation 80, no. 3 (2022): 253–65. http://dx.doi.org/10.3233/ch-211214.

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BACKGROUND: The incidence of postoperative microcirculatory flow alterations and their effect on outcome have not been studied extensively. OBJECTIVE: This systematic review and meta-analysis were designed to investigate the presence of sublingual microcirculatory flow alterations during the immediate and early postoperative period and their correlation with complications and survival. METHODS: A systematic search of PubMed, Scopus, Embase, PubMed Central, and Google Scholar was conducted for relevant articles from January 2000 to March 2021. Eligibility criteria were randomized controlled and

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Abou-Arab, Osama, Christophe Beyls, Abdelilah Khalipha, et al. "Microvascular flow alterations in critically ill COVID-19 patients: A prospective study." PLOS ONE 16, no. 2 (2021): e0246636. http://dx.doi.org/10.1371/journal.pone.0246636.

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Background Data on microcirculatory pattern of COVID-19 critically ill patients are scarce. The objective was to compare sublingual microcirculation parameters of critically ill patients according to the severity of the disease. Methods The study is a single-center prospective study with critically ill COVID-19 patients admitted in ICU. Sublingual microcirculation was assessed by IDF microscopy within 48 hours of ICU admission. Microcirculatory flow index (MFI), proportion of perfused vessel (PPV), total vessel density (TVD), De Backer score (DBS), perfused vessel density (PVD) and heterogenei

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Artushenko, N. K., D. S. Rybalchenko, and O. N. Mironuk. "Gingiva microhemocircualtion of alveolar processes of maxilla in patients with apparently healthy maxillary antrum and associated with chronic odontogenic polypus maxillary sinusitis." Stomatology for All / International Dental review, no. 2020 2 (91) (June 2020): 4–11. http://dx.doi.org/10.35556/idr-2020-2(91)4-11.

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Conducted a clinical research of tissues in maxillofacial area of patients with maxillary sinusitis confirmed based on X-ray diagnostics and patients without it. Cone beam computed tomography of maxillary antrum and ultrasonic dopplerography of microcirculatory vessels of alveolar ridge mucosa on computer-operated ultrasonic system MM-D-K of SP Minimax, St. Petersburg, were used in the research. It is established that as a result of continuous chronic polypoid changes of upper layers of maxillary antrum mucosa and compression of stroma polypuses with microcirculatory vessels in them, compensat

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Krylov, V. E., M. M. Ibatullin, E. K. Valeev, and V. N. Padiryakov. "Changes in the brain microcirculatory bed in craniocerebral trauma." Kazan medical journal 69, no. 1 (1988): 66–68. http://dx.doi.org/10.17816/kazmj97032.

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The microcirculatory bed is an important department of the circulatory system and determines not only the state of peripheral hemodynamics but also the trophic function of the organs. Microcirculatory bed, including arterioles, precapillaries, capillaries, venules, arteriolovenular anastomoses, constitutes 90% of all blood vessels [9, 18J. Arterioles - long meandering vessels 30-40 in diameter - are divided into terminal and mesarterioles. Precapillaries are 15-20 in diameter and regulate blood flow to true capillaries. Arterioles and precapillaries perform a transport function, delivering nut

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Lymanska, A. Yu. "“Reach the cells”: microcirculatory support." Infusion & Chemotherapy, no. 3.2 (December 15, 2020): 168–69. http://dx.doi.org/10.32902/2663-0338-2020-3.2-168-169.

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Background. Vessels of the microcirculatory tract provide regulatory, drainage, thermocontrol and signal functions. Disorders of these vessels are the part of the pathogenesis of coronary heart disease, endarteritis obliterans, Raynaud’s disease, etc. Common causes of microcirculation disorders include disorders of central and regional blood circulation, impaired blood volume and viscosity, impaired permeability of microvessel walls. Objective. To describe the features of microcirculatory support. Materials and methods. Analysis of literature sources on this topic. Results an

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Belousoviene, Egle, Inga Kiudulaite, Vidas Pilvinis, and Andrius Pranskunas. "Links between Endothelial Glycocalyx Changes and Microcirculatory Parameters in Septic Patients." Life 11, no. 8 (2021): 790. http://dx.doi.org/10.3390/life11080790.

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The glycocalyx is an endothelial surface layer that is essential for maintaining microvascular homeostasis. Impaired integrity of the endothelial glycocalyx may be directly related to the development of microvascular dysfunction. To explore this hypothesis, we conducted a prospective observational study on adult patients diagnosed with sepsis. The study aimed to evaluate the degree of damage to the glycocalyx and to identify correlations between microcirculatory parameters and glycocalyx thickness based on capillary diameter. Sublingual microcirculation was examined using a handheld Cytocam-in

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VILSER, W., and B. SEIFERT. "Dynamic vessel analysis for assessing endothel dysfunction of microcirculatory vessels - method, model and results." Acta Ophthalmologica 86 (September 4, 2008): 0. http://dx.doi.org/10.1111/j.1755-3768.2008.5311.x.

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Allaqaband, Hassan, David D. Gutterman, and Andrew O. Kadlec. "Physiological Consequences of Coronary Arteriolar Dysfunction and Its Influence on Cardiovascular Disease." Physiology 33, no. 5 (2018): 338–47. http://dx.doi.org/10.1152/physiol.00019.2018.

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To date, the major focus of diagnostic modalities and interventions to treat coronary artery disease has been the large epicardial vessels. Despite substantial data showing that microcirculatory dysfunction is a strong predictor of future adverse cardiovascular events, very little research has gone into developing techniques for in vivo diagnosis and therapeutic interventions to improve microcirculatory function. In this review, we will discuss the pathophysiology of coronary arteriolar dysfunction, define its prognostic implications, evaluate the diagnostic modalities available, and provide s

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Redondo, Patricia de Albuquerque Garcia, Fernanda Gubert, Camila Zaverucha-do-Valle, et al. "Lymphatic vessels in human adipose tissue." Cell and Tissue Research 379, no. 3 (2019): 511–20. http://dx.doi.org/10.1007/s00441-019-03108-5.

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AbstractDespite being considered present in most vascularised tissues, lymphatic vessels have not been properly shown in human adipose tissue (AT). Our goal in this study is to investigate an unanswered question in AT biology, regarding lymphatic network presence in tissue parenchyma. Using human subcutaneous (S-) and visceral (V-) AT samples with whole mount staining for lymphatic specific markers and three-dimensional imaging, we showed lymphatic capillaries and larger lymphatic vessels in the human VAT. Conversely, in the human SAT, microcirculatory lymphatic vascular structures were rarely

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Marcoccia, Antonella, Peter F. Klein-Weigel, Michael E. Gschwandtner, et al. "Microcirculatory assessment of vascular diseases." Vasa 49, no. 3 (2020): 175–86. http://dx.doi.org/10.1024/0301-1526/a000851.

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Summary. The term “microcirculation” refers to the terminal vascular network of the body, which includes arterioles, capillaries, venules as well as initial lymphatic vessels. Additionally, it insinuates to their unique function in thermoregulation, fluid balance, maintenance of cellular exchange, and metabolism. Disturbances of microvascular function were identified to precede macrovascular involvement in the presence of cardiovascular risk factors and is the hallmark of terminal disease stages like critical limb or acral ischemia. Nevertheless, despite its obvious significance in vascular me

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Arakawa, Christopher, Celina Gunnarsson, Caitlin Howard, et al. "Biophysical and biomolecular interactions of malaria-infected erythrocytes in engineered human capillaries." Science Advances 6, no. 3 (2020): eaay7243. http://dx.doi.org/10.1126/sciadv.aay7243.

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Microcirculatory obstruction is a hallmark of severe malaria, but mechanisms of parasite sequestration are only partially understood. Here, we developed a robust three-dimensional microvessel model that mimics the arteriole-capillary-venule (ACV) transition consisting of a narrow 5- to 10-μm-diameter capillary region flanked by arteriole- or venule-sized vessels. Using this platform, we investigated red blood cell (RBC) transit at the single cell and at physiological hematocrits. We showed normal RBCs deformed via in vivo–like stretching and tumbling with negligible interactions with the vesse

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Donati, Abele, Roberta Domizi, Elisa Damiani, Erica Adrario, Paolo Pelaia, and Can Ince. "From Macrohemodynamic to the Microcirculation." Critical Care Research and Practice 2013 (2013): 1–8. http://dx.doi.org/10.1155/2013/892710.

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ICU patients need a prompt normalization of macrohemodynamic parameters. Unfortunately, this optimization sometimes does not protect patients from organ failure development. Prevention or treatment of organ failure needs another target to be pursued: the microcirculatory restoration. Microcirculation is the ensemble of vessels of maximum 100 m in diameter. Nowadays the Sidestream Dark Field (SDF) imaging technique allows its bedside investigation and a recent round-table conference established the criteria for its evaluation. First, microcirculatory derangements have been studied in sepsis: th

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Kovach, I., N. Gutarova, and V. Alekseeva. "THE EFFECT OFPRP-THERAPY ON THE STATE OFTHE MICROCIRCULATORY BED USING FIXED ORTHODONTIC APPLIANCES." Experimental and Clinical Medicine 86, no. 1 (2020): 4–9. http://dx.doi.org/10.35339/ekm.2020.86.01.01.

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The effect of PRP-therapy on the state of the vessels of the microvasculature was determined using invariable orthodontic appliances (FOAs). The experiments were carried out on 32 male rabbits of the Dutch breed aged 9 months, which were evenly distributed into four groups: control and experimental groups (I, II, III), 8 animals each. It has been established that treatment with FOAs leads to deterioration of the microcirculatory bed vessels, the development of ischemia and necrosis of the oral mucosa. The use of antibacterial drugs against the background of FOAs leads to a weakly pronounced ef

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Gavrilin, Mikhail A., Kyle Porter, Alexandre Samouilov, and Rami N. Khayat. "Pathways of Microcirculatory Endothelial Dysfunction in Obstructive Sleep Apnea: A Comprehensive Ex Vivo Evaluation in Human Tissue." American Journal of Hypertension 35, no. 4 (2021): 347–55. http://dx.doi.org/10.1093/ajh/hpab169.

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Abstract Background The mechanism and markers of cardiovascular disease (CVD) in obstructive sleep apnea (OSA) remain unknown. The microcirculation is the site of early changes in OSA patients who are free of CVD risk. Methods Patients with newly diagnosed moderate to severe OSA (n = 7) were studied before and 12 weeks after intensive treatment with continuous positive airway pressure (CPAP), along with weight and age matched controls (n = 7). Microcirculatory vessels were isolated from gluteal biopsies and changes in critical functional genes were measured. Results The following genes changed

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. Kozlov, V., F. Litvin, and S. Ryzhakin. "Laser photostimulation of the blood flow in pial microcirculatory vessels." Pacific Medical Journal 64, no. 2 (2016): 90–93. http://dx.doi.org/10.17238/pmj1609-1175.2016.2.90-93.

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Soldatov, A. A. "Organ blood flow and vessels of microcirculatory bed in fish." Journal of Evolutionary Biochemistry and Physiology 42, no. 3 (2006): 243–52. http://dx.doi.org/10.1134/s002209300603001x.

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Tsareva, I.A., G.T. Ivanova, and G.I. Lobov. "PECULIARITIES OF FUNCTIONAL STATE OF MICROCIRCULATORY VESSELS AND MESENTERIC ARTERIES IN MALE SHR AND WISTAR KYOTO RATS WHEN METABOLIC SYNDROME IS INDUCED BY FRUCTOSE DIET AT EARLY STAGES OF DEVELOPMENT." Bulletin of Donetsk National University. Series А. Natural Sciences, no. 3 (September 13, 2024): 100–109. https://doi.org/10.5281/zenodo.13758624.

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In our study we investigated early functional changes in microcirculatory vessels and mesenteric arteries in SHR and Wistar Kyoto (WK) rats under modeling of metabolic syndrome (MetS) by fructose load in drinking water. Dietary rats showed: arterial hypertension (AH), increased fasting glycemia, dyslipidemia accompanied by increased triglyceride (TG) concentration, increased total cholesterol (TC) level, increased low-density lipoprotein cholesterol (LDL-C) concentration, and increased uric acid (UA) concentration. It is worth noting that the level of systolic (CAD) and diastolic blood pressur

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Parazynski, S. E., B. J. Tucker, M. Aratow, A. Crenshaw, and A. R. Hargens. "Direct measurement of capillary blood pressure in the human lip." Journal of Applied Physiology 74, no. 2 (1993): 946–50. http://dx.doi.org/10.1152/jappl.1993.74.2.946.

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In this study, we developed and tested a new procedure for measuring microcirculatory blood pressures above heart level in humans. Capillary and postcapillary venule blood pressures were measured directly in 13 human subjects by use of the servo-nulling micropressure technique adapted for micropuncture of lip capillaries. Pressure waveforms were recorded in 40 separate capillary vessels and 14 separate postcapillary venules over periods ranging from 5 to 64 s. Localization and determination of capillary and postcapillary vessels were ascertained anatomically before pressure measurements. Capil

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Yarygin, Oleg A., Lina V. Kamyshanova, Ivan I. Surganov, Elena N. Iarygina, and Yuliya A. Makedonova. "Interrelation of microcirculatory changes in general blood flow and periodontal tissues in pregnant women." Saratov Journal of Medical Scientific Research 20, no. 4 (2024): 376–80. https://doi.org/10.15275/ssmj376.

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Objective: to determine the relationship of microcirculatory changes in general blood flow and periodontal tissues in pregnant women. Material and methods. 98 pregnant women participated in the examination, who underwent an analysis of microcirculatory changes in the fourth finger of the left hand and periodontal. The control group consisted of 30 non-pregnant women. Laser Doppler flowmetric examination was carried out in two stages. At the 1st stage, the vasomotor activity of blood vessels was studied, at the 2nd stage — the contribution of high- and low-frequency oscillations to the overall

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Nepomnyashchaya, Evgeniya M., Elena P. Ulianova, Aleksandr B. Sagakyants, et al. "Factors of angiogenesis (VEGF and CD34) in primary and recurrent soft tissue sarcomas." Journal of Clinical Oncology 38, no. 15_suppl (2020): e23545-e23545. http://dx.doi.org/10.1200/jco.2020.38.15_suppl.e23545.

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e23545 Background: The tumor ability to induce and maintain angiogenesis is one of the main stages of its development. Studies of molecular mechanisms of angiogenesis showed that the dynamic balance that ensures the formation and development of new vessels inside the tumor depends on pro- and anti-angiogenic factors. VEGF and the CD34 endothelial cell marker are considered among the main activators of angiogenesis. Our purpose was to study characteristics of angiogenesis in primary and recurrent soft tissue sarcomas. Methods: The study included 30 patients with primary sarcomas (group 1) and 2

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Stefanovic, Bojana, Elizabeth Hutchinson, Victoria Yakovleva, et al. "Functional Reactivity of Cerebral Capillaries." Journal of Cerebral Blood Flow & Metabolism 28, no. 5 (2007): 961–72. http://dx.doi.org/10.1038/sj.jcbfm.9600590.

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The spatiotemporal evolution of cerebral microcirculatory adjustments to functional brain stimulation is the fundamental determinant of the functional specificity of hemodynamically weighted neuroimaging signals. Very little data, however, exist on the functional reactivity of capillaries, the vessels most proximal to the activated neuronal population. Here, we used two-photon laser scanning microscopy, in combination with intracranial electrophysiology and intravital video microscopy, to explore the changes in cortical hemodynamics, at the level of individual capillaries, in response to stead

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Jung, Christian, Alexander Lauten, Christoph Rödiger, Florian Krizanic, Hans R. Figulla, and Markus Ferrari. "Effect of intra-aortic balloon pump support on microcirculation during high-risk percutaneous intervention." Perfusion 24, no. 6 (2009): 417–21. http://dx.doi.org/10.1177/0267659109358208.

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Background: Intra-aortic balloon counter-pulsation (IABP) is recommended for hemodynamic support in cardiogenic shock. In addition, it can be applied during high-risk percutaneous interventions (PCI). While IABP support improves microflow in cardiogenic shock, its effect in hemodynamically stable patients is still unclear. We, therefore, sought to evaluate the effect of IABP treatment on microflow in hemodynamically stable patients undergoing elective high-risk PCI. Methods: In six patients with >" xbd="892" xhg="869" ybd="1310" yhg="1284"/>50% left main stenosis, microflow was evaluated

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Trieu, Michelle, Matijs van Meurs, Anoek L. I. van Leeuwen, et al. "Vasculotide, an Angiopoietin-1 Mimetic, Restores Microcirculatory Perfusion and Microvascular Leakage and Decreases Fluid Resuscitation Requirements in Hemorrhagic Shock." Anesthesiology 128, no. 2 (2018): 361–74. http://dx.doi.org/10.1097/aln.0000000000001907.

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Abstract Background Microcirculatory dysfunction is associated with multiple organ failure and unfavorable patient outcome. We investigated whether therapeutically targeting the endothelial angiopoietin/Tie2 system preserves microvascular integrity during hemorrhagic shock. Methods Rats were treated with the angiopoietin-1 mimetic vasculotide and subjected to hemorrhagic shock and fluid resuscitation. Microcirculatory perfusion and leakage were assessed with intravital microscopy (n = 7 per group) and Evans blue dye extravasation (n = 8 per group), respectively. The angiopoietin/Tie2 system wa

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Karaganov, K. S., O. A. Slepova, A. S. Lishuta, N. I. Solomakhina, and Yu N. Belenkov. "Medium-term Effects of Enhanced External Counterpulsation in the Structural and Functional Parameters of Blood Vessels in Patients with Coronary Artery Disease." Rational Pharmacotherapy in Cardiology 17, no. 4 (2021): 557–63. http://dx.doi.org/10.20996/1819-6446-2021-08-03.

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Aim. To study the mid-term effects of enhanced external counterpulsation (EECP) in the structural and functional parameters of blood vessels, exercise tolerance and quality of life indicators in patients with verified coronary artery disease (CAD).Material and methods. Patients (n=70) with verified stable CAD (angina pectoris class II-III) complicated by chronic heart faillure class II-III (NYHA) were included in the study. Data from 65 patients (48 to 74 years old; 45 men and 20 women) are included in the final analysis. All patients had a course of EECP (35 hours procedures with a compressio

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Kozlov, V. I., S. M. Ryzhakin, and E. G. Sabantseva. "Effects of exogenous nitric oxide on blood microcirculation: experimental research of therapeutic effect." PULMONOLOGIYA 34, no. 4 (2024): 603–5. http://dx.doi.org/10.18093/0869-0189-2024-34-4-603-605.

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Currently, nitric oxide (NO) is considered a signaling molecule that acts as a universal regulator of many physiological processes in the body. The purpose of this research was to study the effects of exogenous NO on microcirculatory vessels and their blood flow under experimental conditions for the pathogenetic justification of NO therapy and correction of microcirculatory disorders. Methods. Effects of exogenic NO on microvessels of cranial pia mater were studied in white Wistar rats. Another set of experiments was carried out in hamsters to correct microcirculatory disorders caused by infla

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Danilov, O. D., V. I. Shepitko, O. S. Yakushko, E. V. Stetsuk, and N. V. Boruta. "MORPHOLOGICAL CHARACTERISTICS OF THE TRIGEMINAL NODE OF RATS WHEN CRYOPRESERVED PLACENTA IS INTRODUCED." Актуальні проблеми сучасної медицини: Вісник Української медичної стоматологічної академії 22, no. 3-4 (2022): 152–56. http://dx.doi.org/10.31718/2077-1096.22.3.4.152.

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Cryopreserved placenta preparations have a unique composition of biologically active substances, which determines their multifaceted effect. The aim of our study was to investigate the morphological features of the trigeminal node of rats when cryopreserved placenta was injected. The conducted experimental study showed that a single subcutaneous injection of cryopreserved placenta causes a reaction of the vessels of the microcirculatory bed of the trigeminal node of rats in the first two weeks of observation in the form of an expansion of the diameter of arterioles, capillaries and venul

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Contreras-Sánchez, Héctor A., William Jeffrey Zabel, Costel Flueraru, Lothar Lilge, Edward Taylor, and Alex Vitkin. "Characterizing Normal and Tumour Blood Microcirculatory Systems Using Optical Coherence Tomography." Photonics 11, no. 9 (2024): 891. http://dx.doi.org/10.3390/photonics11090891.

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Blood vessels transport blood and deliver essential molecules to cells. In cancer, the tumour vasculature evolves very differently from healthy tissue, not only in morphology but also in functionality. Comprehensive 3D in vivo imaging of the tumour microcirculatory system thus might lead to a clearer understanding of the vascular role in tumour growth and response to cancer therapy. Here, we employed two optical coherence tomography (OCT) extensions, speckle-variance and Doppler, to study the microvascular architecture and blood flow in normal murine and xenograft tumour tissue. We explored th

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Kotan, Robert, Katalin Peto, Adam Deak, Zsolt Szentkereszty, and Norbert Nemeth. "Hemorheological and Microcirculatory Relations of Acute Pancreatitis." Metabolites 13, no. 1 (2022): 4. http://dx.doi.org/10.3390/metabo13010004.

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Acute pancreatitis still means a serious challenge in clinical practice. Its pathomechanism is complex and has yet to be fully elucidated. Rheological properties of blood play an important role in tissue perfusion and show non-specific changes in acute pancreatitis. An increase in blood and plasma viscosity, impairment of red blood cell deformability, and enhanced red blood cell aggregation caused by metabolic, inflammatory, free radical-related changes and mechanical stress contribute to the deterioration of the blood flow in the large vessels and also in the microcirculation. Revealing the s

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Yokoyama, Yukihiro, Rajiv Baveja, Natalie Sonin, Mark G. Clemens, and Jian X. Zhang. "Hepatic neovascularization after partial portal vein ligation: novel mechanism of chronic regulation of blood flow." American Journal of Physiology-Gastrointestinal and Liver Physiology 280, no. 1 (2001): G21—G31. http://dx.doi.org/10.1152/ajpgi.2001.280.1.g21.

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The present study was undertaken to investigate hepatic microcirculatory response following partial portal vein ligation (PPVL) in rats. Portal pressure was markedly increased 2–6 wk after PPVL, but no significant reduction in sinusoidal perfusion and hepatocellular injury were detected. However, marked neovascularization was observed in PPVL rats using intravital microscopy and scanning electron microscopy (SEM). Extremely high red blood cell velocity (2,000–4,900 μm /s) was seen in these vessels. Injection of fluorescein sodium via the carotid artery revealed that the neovessels originated f

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Makavos, George, Maria Varoudi, Konstantina Papangelopoulou, et al. "Echocardiography in Autoimmune Rheumatic Diseases for Diagnosis and Prognosis of Cardiovascular Complications." Medicina 56, no. 9 (2020): 445. http://dx.doi.org/10.3390/medicina56090445.

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Autoimmune rheumatic diseases are systemic diseases frequently affecting the heart and vessels. The main cardiovascular complications are pericarditis, myocarditis, valvular disease, obstructive coronary artery disease and coronary microcirculatory dysfunction, cardiac failure and pulmonary hypertension. Echocardiography, including transthoracic two and three-dimensional echocardiography, Doppler imaging, myocardial deformation and transesophageal echo, is an established and widely available imaging technique for the identification of cardiovascular manifestations that are crucial for prognosi

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Archakova, L. I., E. I. Kalinovskaya, T. E. Kuznetsova, et al. "Structural and functional mechanisms of reactive changes in vasoconstrictors, internal organs and skin with metabolic syndrome and toxic action of doxorubicin." Proceedings of the National Academy of Sciences of Belarus, Medical series 16, no. 3 (2019): 283–90. http://dx.doi.org/10.29235/1814-6023-2019-16-3-283-290.

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A comparative analysis of structural organization changes in skin microcirculatory vessels, serum level of leptin, diponectin, resistin in the ase of metabolic syndrome and doxorubicin intoxication was performed. It was shown that hypertrophy of the muscle fibers, perivascular space edema, and skin arteriole spasm in the metabolic syndrome accompanied by a structural reorganization of the organs and their vessels by the type of dystrophy. In the case of doxorubicin intoxication, the alteration processes were dominant. Changes in the level of hormones leptin adiponectin and resistin in the meta

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Chalkias, Athanasios, Nikolaos Papagiannakis, Konstantina Katsifa, et al. "Characterization of Sublingual Microvascular Tortuosity in Steady-State Physiology and Septic Shock." Biomedicines 13, no. 3 (2025): 691. https://doi.org/10.3390/biomedicines13030691.

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Background: The characteristics of hemodynamic coherence in healthy states and disease remain unknown. Capillary tortuosity is a morphologic variant of microcirculatory vessels, but its effects have generally not been considered in the assessment of tissue perfusion and oxygenation. We investigated the role of sublingual capillary tortuosity in the hemodynamic coherence of anesthetized adult individuals with steady-state physiology (ASA 1) and patients with septic shock requiring emergency abdominal surgery (ASA 4E and 5E). Methods: Sublingual macro and microcirculatory variables, oxygen trans

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Fedorov, S. M., та V. M. Zalessky. "Молекулярно-клеточные механизмы действия светового излучения и слабого магнитного поля на кровь и системы микроциркуляции при использовании современной магнитолазерной аппаратуры (обзор литературы)". Likarska sprava, № 5 (28 серпня 2012): 3–14. http://dx.doi.org/10.31640/ls-2012-5-01.

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This review covers the molecular-cellular mechanisms of therapeutic action of light and magnetic field on blood components, blood vessels and the microcirculation system. Noted the role of the magnetic field as a trigger of vasodilation/vasoconstriction, depending on the initial vascular tone. Discussed the importance of NO-dependent effects of magnetic field on the microcirculatory response and angiogenesis.

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Tanaka, Koji, Masato Okigami, Yuji Toiyama, et al. "In vivo real-time imaging of tumor microcirculatory alterations in colorectal liver metastatic xenografts by chemotherapy using multiphoton microscopy." Journal of Clinical Oncology 30, no. 15_suppl (2012): e21053-e21053. http://dx.doi.org/10.1200/jco.2012.30.15_suppl.e21053.

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e21053 Background: Tumor endothelium is a distinct target for anticancer treatments of metastatic colorectal cancer. Various chemotherapeutics themselves have anti-angiogenic effects on tumor microenvironment by targeting proliferative endothelial cells during tumor angiogenesis. In this study, we imaged the dynamics of tumor microcirculation of colorectal liver metastasis in living mice in vivo real-time using two-photon laser scanning microscopy (TPLSM), and evaluated the microcirculatory alterations in tumor microenvironment by chemotherapy. Methods: Red fluorescent protein expressing human

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Kodirova, Nargizakhon Umarovna. "INFLUENCE OF SMOKING TOBACCO ON THE BLOOD VESSELS AND MICROCIRCULATION." EURASIAN JOURNAL OF MEDICAL AND NATURAL SCIENCES 2, no. 12 (2022): 92–95. https://doi.org/10.5281/zenodo.7312701.

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The purpose of the review was to study certain aspects of the effect of tobacco smoking on the state of the cardiovascular system, microvasculature in young healthy people and patients with ischemic heart disease. Certain aspects of drug therapy for coronary heart disease in smokers are also considered. Patients and the effectiveness of the use of antianginal drugs from the group of β-blockers. States microcirculatory bed and the effect of tobacco smoking on it by biomicroscopy of the vessels of the bulbar conjunctiva is poorly understood to date.

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Johnson, Paul C., Kim Vandegriff, Amy G. Tsai, and Marcos Intaglietta. "Effect of acute hypoxia on microcirculatory and tissue oxygen levels in rat cremaster muscle." Journal of Applied Physiology 98, no. 4 (2005): 1177–84. http://dx.doi.org/10.1152/japplphysiol.00591.2004.

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Repeated exposure to brief periods of hypoxia leads to pathophysiological changes in experimental animals similar to those seen in sleep apnea. To determine the effects of such exposure on oxygen levels in vivo, we used an optical method to measure Po2 in microcirculatory vessels and tissue of the rat cremaster muscle during a 1-min step reduction of inspired oxygen fraction from 0.21 to 0.07. Under control conditions, Po2 was 98.1 ± 1.9 Torr in arterial blood, 52.2 ± 2.8 Torr in 29.0 ± 2.7-μm arterioles, 26.8 ± 1.7 Torr in the tissue interstitium near venous capillaries, and 35.1 ± 2.6 Torr i

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Shadlinsky, V. B., G. Sh Garaev, and Kh F. Khydyrova. "THE MORPHOLOGY OF THE MICROCIRCULATORY BED OF THE LIVER DURING EXPERIMENTAL INHALATION OF HYDROCHLORIC ACID VAPORS." Morphological newsletter 25, no. 3 (2017): 55–57. http://dx.doi.org/10.20340/mv-mn.17(25).03.55-57.

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The aim of the study was to investigate changes in the hepatic vessels of small diameter under the influence of exogenous intoxication caused by respiratory way. Experiments were carried out on 16 rabbits of the chinchilla breed, which were divided equally into 4 groups. The first group included the control animals whose vascular structures were considered intact. The second group included the animal liver preparations which were studied on the 10th day of the experiments, and the III group animals were investigated on the 30th day of the experiment. The animals included into the IV group were

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Tybinka, A. M. "Структура та розвиток судин брижі кишечнику". Scientific Messenger of LNU of Veterinary Medicine and Biotechnologies 19, № 78 (2017): 62–67. http://dx.doi.org/10.15421/nvlvet7813.

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The review of the results of various scientific studies, reflecting the processes of age formation of morphological and functional features of the mesenteric intestinal vessels, is presented. In this case, it has been shown that the formation of the microcirculatory channel of mesentery begins in its separate segments. Firstly, there are separate arterial and venous loops, in the middle of which one can see the capillaries. The branched net of capillaries is gradually formed and the number of arterioles and venules increases, and their diameter also increases. This process is closely related t

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Villela, Nivaldo Ribeiro, Luiz Guilherme Kramer-Aguiar, Daniel Alexandre Bottino, Nicolas Wiernsperger, and Eliete Bouskela. "Metabolic disturbances linked to obesity: the role of impaired tissue perfusion." Arquivos Brasileiros de Endocrinologia & Metabologia 53, no. 2 (2009): 238–45. http://dx.doi.org/10.1590/s0004-27302009000200015.

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Associated with elevated risk of cardiovascular events and cancer, obesity is a worldwide problem affecting developed and developing countries. Microcirculatory vessels, represented by arterioles, capillaries and venules (mean internal diameter < 100 µm), are the place where blood/tissue nutrition and exchange effectively take place. Microvascular dysfunction is an early event in obesity probably secondary to endothelial dysfunction and capillaries rarefaction. New research techniques allow the investigation of the microcirculation in different vascular beds in humans. Studies suggest a lin

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Kuimova, Zhanna Vladimirovna, Elizaveta Vladimirovna Kolomiets, and Diana Huseynovna Ismailova. "Modern approaches to the diagnosis of occupational hearing loss in workers exposed to noise." Terapevt (General Physician), no. 6 (June 23, 2022): 13–17. http://dx.doi.org/10.33920/med-12-2206-02.

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Rheovasography (RVG) is a modern non-invasive method for studying the intensity of peripheral circulation, the severity of collateral circulation, assessing the state of vascular tone and the venous system. Impedancemetry allows you to establish, evaluate the function of the endothelial layer of blood vessels, the elastic properties of arteries and the state of the microcirculatory bed, which allows you to choose the most optimal treatment tactics.

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Granja, Tiago, Sérgio Faloni de Andrade, and Luis Monteiro Rodrigues. "Optoaccoustic Tomography – good news for microcirculatory research." Journal Biomedical and Biopharmaceutical Research 18, no. 2 (2022): 1–13. http://dx.doi.org/10.19277/bbr.18.269.

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Tomographic imaging is a well established technology in preventive medicine and biomedical research, although not without limitations and concerns. Optoacoustic tomography (OAT) is a recent development that bridges optical and sonographic techniques to solve spatial resolution in deep-tissue imaging. In addition to safety advantages, OAT allows multiple wavelength readings for natural thermoelastic chromophores. In this study, we explore Multi Spectral Optoacoustic Tomography (MSOT) capacities to simultaneously acquire three independent chromophores – deoxygenated haemoglobin (Hb), oxygenated

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Granja, Tiago, Sérgio Faloni de Andrade, and Luis Monteiro Rodrigues. "Optoaccoustic Tomography – good news for microcirculatory research." Journal Biomedical and Biopharmaceutical Research 18, no. 2 (2022): 49. http://dx.doi.org/10.19277/bbr.18.2.269.

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Tomographic imaging is a well established technology in preventive medicine and biomedical research, although not without limitations and concerns. Optoacoustic tomography (OAT) is a recent development that bridges optical and sonographic techniques to solve spatial resolution in deep-tissue imaging. In addition to safety advantages, OAT allows multiple wavelength readings for natural thermoelastic chromophores. In this study, we explore Multi Spectral Optoacoustic Tomography (MSOT) capacities to simultaneously acquire three independent chromophores – deoxygenated haemoglobin (Hb), oxygenated

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Zelinsky, В. A., and S. A. Sokur. "Pathophysiology of the microcirculatory bed in obesity." Problems of Endocrinology 41, no. 4 (1995): 21–23. http://dx.doi.org/10.14341/probl11458.

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A total of 207 patients with alimentary constitutional and hypothalamic obesity were examined in order to assess the status of the microcirculatory bed, including the status of capillary walls, hemocirculation, transcapillary metabolism, oxygen delivery to tissues in patients with various forms of obesity. Bulbobiomicroscopy, assessment of capillary wall permeability by the hydrostatic test, polarographic study of oxygen tension in the skin using oxygen and ischemic test were employed. Obese patients were found to develop appreciable microcirculatory disorders (vascular, intravascular, extrava

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