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Dissertations / Theses on the topic 'Microcrystalline cellulose'

Author: Grafiati

Published: 4 June 2021

Last updated: 26 July 2025

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1

Steele, David Fraser. "Amine/microcrystalline cellulose interactions." Thesis, University of Bath, 2002. https://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.275882.

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2

Oza, Kamlesh P. "Colloidal microcrystalline cellulose stabilized emulsions /." The Ohio State University, 1987. http://rave.ohiolink.edu/etdc/view?acc_num=osu1487585645576756.

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3

Luukkonen, Pirjo. "Rheological properties and the state of water of microcrystalline cellulose and silicified microcrystalline cellulose wet masses." Helsinki : University of Helsinki, 2001. http://ethesis.helsinki.fi/julkaisut/mat/farma/vk/luukkonen/rheologi.pdf.

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4

Kiziltas, Alper. "Microcrystalline Cellulose-Filled Engineering Thermoplastic Composites." Fogler Library, University of Maine, 2009. http://www.library.umaine.edu/theses/pdf/KiziltasA2009.pdf.

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5

Khalaf, Ahmed S. "Pharmaceutical characterisation of novel microcrystalline cellulose." Thesis, University of Bath, 2000. https://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.288235.

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6

Nilsson, Martin. "Water-Induced Charge Transport in Microcrystalline Cellulose." Doctoral thesis, Uppsala : Acta Universitatis Upsaliensis : Univ.-bibl. [distributör], 2006. http://urn.kb.se/resolve?urn=urn:nbn:se:uu:diva-6815.

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7

Fielden, Krystyna Elzbieta. "Extrusion and spheronization of microcrystalline cellulose and lactose mixtures." Thesis, University College London (University of London), 1987. http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.445344.

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8

Sidwall, Thygesen Signe, Astrid Berghult, and Camilla Öhman. "Prediction of elastic properties of nanofibrillated cellulose and microcrystalline cellulose : by mathematical models and tensile testing." Thesis, Uppsala universitet, Institutionen för teknikvetenskaper, 2012. http://urn.kb.se/resolve?urn=urn:nbn:se:uu:diva-177367.

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9

Jansson, Felisa. "The Effect of Microcrystalline Cellulose as cushioning excipient during controlled release." Thesis, Linköpings universitet, Kemi, 2017. http://urn.kb.se/resolve?urn=urn:nbn:se:liu:diva-134431.

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In the pharmaceutical industry, it is always important to have reproducible processes and raw materials of high quality to ensure good quality products. AstraZeneca, that is a leading manufacturer of different pharmaceuticals, works according to GMP to make sure that their processes deliver products of the same quality every time. A problem that has occurred at AstraZeneca is when a raw material is not properly understood and variations in the raw material affects the final product. Variations in drug release in one of AstraZeneca´s products, Product X, has been linked to the cushioning excipi

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10

Deng, Xinying. "Toughening of natural-fibre composites using nano- and microcrystalline cellulose particles." Thesis, Imperial College London, 2018. http://hdl.handle.net/10044/1/64794.

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Environmental concerns have prompted research into natural materials to improve sustainability. Cellulose has some of the highest mechanical properties among naturally-derived materials, and natural-fibre composites have better specific stiffness than glass-fibre composites, and are thus increasingly used in the transport and construction sectors. However, cellulose is hydrophilic and it is difficult to obtain a uniform dispersion of cellulose modifiers in epoxy polymers. This makes it challenging to achieve high performance natural-fibre composites with good delamination resistance, which is

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11

Thomas, William Iwan. "The effects of material characteristics on the compression and properties of dry coated tablets." Thesis, University of Sunderland, 1998. http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.264762.

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12

Chatrath, Meena. "The effect of wet granulation on the physico-mechanical characteristics of microcrystalline cellulose." Thesis, University of Bath, 1992. https://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.306397.

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13

MacRitchie, Kenneth Andrew. "Rheological evaluation of mixtures of lactose, microcrystalline cellulose and water suitable for all preparation of spherical granules." Thesis, University College London (University of London), 1993. http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.389915.

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14

Mihranyan, Albert. "Engineering of Native Cellulose Structure for Pharmaceutical Applications : Influence of Cellulose Crystallinity Index, Surface Area and Pore Volume on Sorption Phenomena." Doctoral thesis, Uppsala : Acta Universitatis Upsaliensis : Universitesbiblioteket [distributör], 2005. http://urn.kb.se/resolve?urn=urn:nbn:se:uu:diva-4752.

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15

Chinyemba, Patience. "Use of Aloe vera and Aloe marlothii materials as excipients in beads produced by extrusion-spheronization / Patience Chinyemba." Thesis, North-West University, 2012. http://hdl.handle.net/10394/9641.

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Microcrystalline cellulose (MCC) is the most commonly used excipient in the manufacture of spherical particles or beads by extrusion spheronisation. However, the use of MCC in beads has its limitations such as prolonged release of drugs due to lack of disintegration. The aim of this study was to determine if Aloe vera and Aloe marlothii leaf materials can be used as excipients in the production of beads prepared by extrusion spheronisation. A 23 full factorial design was employed for optimisation and to explore the effects of the concentration of MCC, polyvinylpyrrolidone and aloe materials on

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16

Lima, Neto Severino Antonio de. "Determinacao das caracteristicas de intumescimento de adjuvantes." reponame:Biblioteca Digital de Teses e Dissertações da UFRGS, 1996. http://hdl.handle.net/10183/148223.

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O intumescimento é um dos fatores decisivos que influenciam o comportamento de desintegração de formas farmac6uticas compactadas e, consequentemente, o perfil biofarmacêutico de substancias ativas. Entre os diversos adjuvantes empregados para promover a desagregação daquelas formas farmac6uticas nas suas partículas primarias originais, são utilizadas varias substancias, abrangidas pelo conceito de desintegrantes intumescedores. A escolha do adjuvante mais adequado nestes casos pode ser vista como uma atividade que exige o gasto considerável de tempo e de custos elevados. Além disto deve ser le

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17

Rosa, André Luiz. "Caracterização físico-química de sistemas coloidais em sprays nasais." Universidade de São Paulo, 2016. http://www.teses.usp.br/teses/disponiveis/46/46137/tde-31102016-090427/.

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Neste trabalho avaliou-se o comportamento coloidal de suspensões nasais contendo micropartículas de celulose (MCC-NaCMC) com o objetivo de desenvolver um produto genérico compatível com o produto referência de mercado. As propriedades reológicas destas formulações possuem alta influência nos atributos críticos de qualidade do produto, como uniformidade de dose, devido sedimentação durante estocagem em prateleira, e também na performance in-vitro/ in-vivo. Realizaram-se testes com diferentes concentrações de MCC-NaCMC e diferentes parâmetros de processo (tempo e taxa de cisalhamento) utilizando

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18

Moraes, Roberta Hansel de. "Avaliação do comportamento de flavonas e flavonóis frente à celulose microcristalina em estado sólido." reponame:Biblioteca Digital de Teses e Dissertações da UFRGS, 2007. http://hdl.handle.net/10183/15282.

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Neste trabalho, foi avaliado o comportamento de alguns flavonóides e do adjuvante tecnológico celulose microcristalina (CMCr) no estado sólido, em relação ao tipo de interação e sua intensidade, quando existente, utilizando misturas físicas equiponderais e na proporção ponderal 1:2, respectivamente, através da calorimetria exploratória diferencial (DSC), análise termogravimétrica e espectroscopia no infravermelho (FTIR). A relação estrutura-propriedade de interação dos flavonóides estudados foi determinada nas possíveis interações sólido-sólido com a celulose microcristalina, correlacionando o

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19

Dong, Xue Min. "Chiral nematic ordered suspensions of cellulose microcrystallites." Thesis, National Library of Canada = Bibliothèque nationale du Canada, 1997. http://www.collectionscanada.ca/obj/s4/f2/dsk2/tape16/PQDD_0024/NQ29924.pdf.

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20

Dong, Xue Min. "Chiral nematic ordered suspensions of cellulose microcrystallites." Thesis, McGill University, 1996. http://digitool.Library.McGill.CA:80/R/?func=dbin-jump-full&object_id=42018.

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Suspensions of rod-like cellulose microcrystallites, 50-250 nm in length and $ sim$7 nm in width, and with negatively charged sulfate groups on the surface have been prepared. When the concentration of cellulose microcrystallites exceeds a critical value, the suspension separates into two phases, forming an upper isotropic phase and a lower chiral nematic anisotropic phase. The critical concentration for phase separation is very sensitive to the ionic strength, particle size, polydispersity of particles, counterion species, and preparation conditions. When the suspension is in pure water and i

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21

Raines, Catherine Lindsay. "The extrusion of various formulations of microcrystalline celluloses." Thesis, University College London (University of London), 1990. http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.309626.

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22

Likhar, Lokesh. "The production of a lyotropic liquid crystal coated powder precursor through twin screw extrusion." Thesis, University of Bradford, 2013. http://hdl.handle.net/10454/6352.

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The twin screw extrusion technique has been explored to produce lyotropic liquid crystal coated powder precursor by exploiting Pluronic F127 thermoreversible gelation property to get powder precursor without granular aggregates or with less compacted granular aggregates. The highly soluble chlorpheniramine maleate loaded in Pluronic F127 solution coated MCC particles prepared through twin screw extrusion was examined to produce the cubic phase (gel) for the development of controlled release formulation and for coating of very fine particles which cannot be achieved by traditional bead coaters.

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23

Berggren, Jonas. "Engineering of Pharmaceutical Particles : Modulation of Particle Structural Properties, Solid-State Stability and Tabletting Behaviour by the Drying Process." Doctoral thesis, Uppsala University, Department of Pharmacy, 2003. http://urn.kb.se/resolve?urn=urn:nbn:se:uu:diva-3353.

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<p>Relationships between stresses during the drying process, particle structural and functional properties, and particle engineering by the drying process were addressed in this thesis. In the first part, the importance of the drying phase and the effect of the drying rate on the intragranular porosity of microcrystalline cellulose pellets were investigated. Differences in porosities of dried pellets could be explained by liquid-related differences in densification during convective drying rather than by differences in densification during wet agglomeration. An increased drying rate gave more

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24

Ming-An, Hsieh, and 謝明安. "Physical Modification of Microcrystalline Cellulose." Thesis, 1998. http://ndltd.ncl.edu.tw/handle/86949810721532249033.

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碩士<br>台北醫學院<br>藥學研究所<br>86<br>Microcrystalline cellulose (MCC) is a material that i s very popularly used as an excipient in the production of tablets as a result that it exhibits the best compactibility i n the direct compression. MCC powders are known to for m tablets mainly through plastic deformation. However, the irregularly shaped particles of MCC, which might improve the tensile strength of tablets as a result of mechanical int erlocking bonding, is responsible for its poor flowability of smaller siz

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25

Ferreira, Stephany Maria Vieira. "Microcrystalline cellulose and sisal fibre reinforced cementitious composites." Master's thesis, 2016. http://hdl.handle.net/1822/49651.

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Dissertação de mestrado integrado em Engenharia Civil (área de especialização em Perfil de Construções)<br>Nas últimas décadas tem existido um crescente interesse em métodos alternativos de reforçar compósitos cimentícios. A utilização de fibras naturais como elemento de reforço tem sido bastante explorada ao longo dos anos, sendo que origina compósitos cimentícios com uma resistência ao impacto e à fissuração superior quando comparados com compósitos cimentícios comuns. Por outro lado, o uso de celulose microcristalina (CMC) também tem sido estudado, principalmente na última década, veri

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26

Lin, Mei-Yin, and 林美吟. "Preparation of porous microcrystalline cellulose and its properties." Thesis, 2011. http://ndltd.ncl.edu.tw/handle/39825336677498915950.

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碩士<br>國立臺灣大學<br>食品科技研究所<br>99<br>According to the study daily sodium intake has a positive correlation with risk of hypertension and cardiovascular disease. In 2010, American Heart Association suggested the food producer to reduce 10-40% sodium content of their products. Obviously, development of salt reduction products is a current trend. This study was divided into two parts. In the first part, the preparation of porous cellulosic materials was employed by enzymatic hydrolysis. In the other part, combination of porous cellulosic material and chitosan was tested to create a complex material t

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27

Tantasucharit, Usicha. "Porosity, surface area and enzymatic saccharification of microcrystalline cellulose." Thesis, 1995. http://hdl.handle.net/1957/25991.

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The research described in this thesis was aimed at understanding how particle size, porosity, and enzyme accessible surface area influence the rate of saccharification of microcrystalline cellulose. Microcrystalline cellulose (MCC) is a commonly used substrate for the study of cellulolytic enzymes. MCC preparations of different particle size are commercially available. In this study, MCC preparations having average particle sizes of 20, 50, and 90 μm were analyzed with respect to their enzyme accessible surface area, chemical and physical properties and rates of enzymatic saccharification. Sac

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28

Jadhav, N., M. Gade, N. Salunkhe, and Anant R. Paradkar. "Extrusion-Spheronization of Talc using Microcrystalline Cellulose as a Pellet Aid: Part I." 2014. http://hdl.handle.net/10454/10463.

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No<br>The aims of the present work were to pelletize talc by extrusion-spheronization technique using microcrystalline cellulose (MCC) as a pelletization aid and to study its performance as a neutral substrate for coating. A 32 factorial design was used to study the effect of independent variables (X1, amount of talc, and X2, MCC) on pellet properties.

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29

Chien-Ming, Hsieh, and 謝堅銘. "Studies on the Characteristics and Functionality of Microcrystalline Cellulose by Co-drying with Excipients." Thesis, 1999. http://ndltd.ncl.edu.tw/handle/67661541500781097649.

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碩士<br>台北醫學院<br>藥學研究所<br>87<br>Microcrystalline cellulose (MCC) is derived from purified wood α-cellulose by a severe acid hydrolysis, yielding a cellulose with a degree of polymerization (D.P.) of about 200 to 300. Because it equipped with an excellent compactibility and a low chemical reactivity, it makes the MCC to become one of the most useful excipient of direct compression tableting. Because the particle shape of MCC is irregular, it causes bad flowability, the variation of tablets weight, and the poor disintegration properties. In an attempt to improve or solve these problems, the aim of

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30

Chi, Chung-Chien, and 紀仲謙. "Preparation of microcrystalline cellulose from by-products of wheat seedling juice and its applications." Thesis, 2010. http://ndltd.ncl.edu.tw/handle/68099513777925296323.

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碩士<br>國立中興大學<br>食品暨應用生物科技學系所<br>98<br>The objective of this study is to evaluate the feasibility of producing microcrystalline cellulose (MCC) from the waste during wheat (Triticum aestivum L.) seedling juice processing by using different concentration of alkaline, acid treatments and drying methods and then measure the physicochemical properties of wheat seedling pomace MCC powders as well as the effects on the texture of jelly products. The results showed that the amount of crude fiber was 39 % and α-cellulose content through purification procedure was 72-77 %, so it was adequate to produce

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31

Wu, Jen-Sen, and 吳振森. "Influence of manufacturing factors on the material properties, mechanical performances and functionalities of microcrystalline cellulose." Thesis, 2001. http://ndltd.ncl.edu.tw/handle/30239967078121586031.

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博士<br>台北醫學院<br>藥學研究所<br>89<br>Due to its excellent compactibility, microcrystalline cellulose (MCC) is one of the most preferred filler-binders in direct compression tablet formulations. However, source and batch variations affect the functionalities of MCC. In modern pharmaceutical industry, the concepts of crystal engineering and particle design are popular to manipulate the mechanical performances and functionalities of excipients. Accordingly, the material properties (molecular structure and the particle properties) may contribute to the mechanical performances and functionalities of MCC.

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32

Chang, Ling-Lan, and 張羚蘭. "Effect of microwave concentration and microcrystalline cellulose addition on physical properties of Ponkon orange jam." Thesis, 2009. http://ndltd.ncl.edu.tw/handle/49602078153514372636.

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碩士<br>國立中興大學<br>食品暨應用生物科技學系<br>97<br>Ponkon is one of the plants from Aurantiodeae. It is originated from Suntara in the middle of India. Ponkon is not only full of pectin and many functional constituents but the main consumption of fruit in Taiwan. The objective of this study is to evaluate the effect of adding isomaltooligosaccharide ( IMO ) to replace sucrose by different ratio and 1 % or 2 % microcrystalline cellulose ( MCC ) addition on physical properties of jams concentrated by microwave heating by using 900W and ( or ) 600W ,and then observe the physical properties of jams during stora

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33

Ferreira, Simão Pedro de Carvalho. "Desenvolvimento de compósitos cimentícios reforçados por celulose microcristalina." Master's thesis, 2016. http://hdl.handle.net/1822/48357.

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Dissertação de mestrado integrado em Engenharia Civil<br>Devido às suas boas propriedades físicas e químicas, os compósitos de matriz cimentícia, que englobam uma mistura de areia, água e certos adjuvantes, são materiais de larga utilização na construção civil, como são os casos das argamassas e dos betões. Com a finalidade de melhorar a performance dos materiais cimentícios têm-se efetuado, recentemente, diversos estudos na área das nanofibras, sendo o caso da adição de microcristais de celulose (MCC) como reforço estrutural. A celulose apresenta-se como um material abundante, muito res

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34

Souza, Filho Aloysio Gomes de. "Estudo da influência da utilização de celulose microcristalina (MCC) e fibras de sisal como reforço multiescala de compósitos cimentícios." Doctoral thesis, 2020. http://hdl.handle.net/1822/76576.

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Tese de doutoramento em Engenharia Têxtil<br>O betão é o material de construção mais utilizado, sendo amplamente aplicado na construção civil. Apesar de os materiais de base cimentícia apresentarem excelente resistência à compressão, possuem algumas limitações e problemas, como baixas resistência à tração e capacidade de deformação, bem como problemas de fissuração. As fibras de base celulósica, nomeadamente as fibras de sisal, podem ser utilizadas para minimizar estes problemas. As fibras de sisal possuem excelentes propriedades mecânicas, não toxicidade, baixo custo e apresentam al

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