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1

Luo, Yiqi. "Chemical applications of microfluidics /." May be available electronically:, 2008. http://proquest.umi.com/login?COPT=REJTPTU1MTUmSU5UPTAmVkVSPTI=&clientId=12498.

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2

Fiorini, Gina S. "Polymeric microfluidic devices : development of thermoset polyester microfluidic devices and use of poly(dimethylsiloxane) devices for droplet applications /." Thesis, Connect to this title online; UW restricted, 2007. http://hdl.handle.net/1773/8627.

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3

Zhang, Yizhe. "Drop-Based Microfluidics for Biological Applications." Thesis, Harvard University, 2015. http://nrs.harvard.edu/urn-3:HUL.InstRepos:17467232.

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Drop-based microfluidic technology has been attracting great attention since the prevalence of soft-lithography techniques in poly-dimethylsiloxane (PDMS) microfluidic device fabrication a decade ago. The miniaturized isolated confinement of the droplet provides an ideal environment to study single cell behaviors in vitro that might otherwise be buried in the ensemble measurements. The effective confinement of the target and its secretion, together with the high-throughput processing capability, holds the promise for efficient target search through large-scale library screening. In fact, in th
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Aubrecht, Donald Michael. "Droplet Microfluidics: Tools for Screening and Sorting Applications." Thesis, Harvard University, 2013. http://dissertations.umi.com/gsas.harvard:11069.

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Microfluidic droplets are a powerful tool for screening large populations of cells, molecules, and biochemical reactions. Droplet systems are able to encapsulate, incubate, screen, and sort millions of samples, providing access to large number statistics that make searching for rare events feasible. Initial development of the microfluidic devices and methods has attracted applications in biology, biochemistry, and material science, but the set of tools remains incomplete. Efforts are required to develop micro-scale droplet analogs for all bulk-scale bench top procedures and instruments. Th
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5

Ambardar, Sharad. "Combining Thermo-plasmonics with Microfluidics for Biological Applications." Scholar Commons, 2018. https://scholarcommons.usf.edu/etd/7600.

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In this project we, for the first time, integrated microfluidics with thermo-plasmonics. While microfluidics is a popular platform allowing experiments with small volumes of fluid, thermo-plasmonics can be used for powerful particle manipulation including capturing, mixing, filtering and projection. Combined, these two techniques give us an opportunity to work with numerous complex fluids containing particles, cells, and micro-beads. Here we designed, developed and tested several devices demonstrating various aspects of this exciting hybrid
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6

Jin, Jing. "Fundamental Investigations and Applications of Liquid Marbles." Thesis, Griffith University, 2020. http://hdl.handle.net/10072/394720.

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Microfluidics has been emerging as a feasible platform technology with broad applications in chemical synthesis, food safety, environmental monitoring, and especially, biomedical diagnostics. As a promising off-channel platform with many intrinsic properties compatible with digital microfluidics, liquid marbles (LMs) play an important role for a range of biochemical applications, such as three-dimensional cell culture and polymerase chain reactions of nucleic acids. LMs are micro-scale liquid droplets encapsulated by a protective coating of hydrophobic micro- or nanoparticles. Due to the non-w
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7

Jang, Ling-Sheng. "Microfluidic mixing technology for biological applications /." Thesis, Connect to this title online; UW restricted, 2003. http://hdl.handle.net/1773/7152.

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8

Owens, Tracie LeeAnne. "Engineering amphiphilic fabrics for microfluidic applications." Diss., Georgia Institute of Technology, 2011. http://hdl.handle.net/1853/42908.

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Woven textile fabrics were designed and constructed from hydrophilic and hydrophobic spun yarns to give planar substrates containing amphiphilic microchannels with defined orientations and locations. Polypropylene fibers were spun to give hydrophobic yarns, and the hydrophilic yarns were spun from a poly(ethylene terephthalate) copolyester. Water wicking rates into the fabrics were measured by video microscopy and longitudinal wicking tests from single drops and from reservoirs. Intra-yarn microchannels in the hydrophilic polyester yarns were shown to selectively transport aqueous fluids, wi
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9

Lamperti, Emanuele. "PDMS based microfluidics membrane contactors for CO2 removal applications." Master's thesis, Alma Mater Studiorum - Università di Bologna, 2018. http://amslaurea.unibo.it/15261/.

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This work proposes a gas-liquid contactor study in microfluidics field, using dense membrane working with a concentration gradient; a microfluidic gas-liquid contactor was developed for CO2 removal and the general idea is to transport CO2 through a polymer dense membrane, followed by its capture by a liquid solvent with chemical absorption. Like recent studies demonstrate, this kind of devices could solve problems related to extracorporeal lung oxygenation (Garofalo, C. Quintavalle, G. Romano, C.M. Croce, 2013) for critical surgical support and critical care medicine, it can work like a real
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10

Du, Ke. "Noval nanoindentation-based techniques of MEMS and microfluidics applications." [Tampa, Fla] : University of South Florida, 2008. http://purl.fcla.edu/usf/dc/et/SFE0002778.

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11

Du, Ke. "Novel Nanoindentation-Based Techniques for MEMS and Microfluidics Applications." Scholar Commons, 2008. https://scholarcommons.usf.edu/etd/220.

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In this thesis, the mechanical characterization of thin films, bulk materials, compliant MEMS and Microfluidics has been discussed. In chapter1 and chapter 2, the Indentation Size Effect (ISE) has been studied for single crystal aluminum and the substrate effect has also been studied for 200 nm gold film on mica substrate and 50 nm gold film on (100) silicon wafer substrate. The mechanical characterization of super hard SiC films (prepared by CVD) has also been discussed. In chapter 3, the actuation of compliant MEMS devices with a nanoindentation apparatus has been investigated. Friction forc
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12

Wilson, Shannon Courtney. "Applications and Advancements of Dynamic Isoelectric Focusing." OpenSIUC, 2014. https://opensiuc.lib.siu.edu/dissertations/865.

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The work in the dissertation expands the applications of DIEF and describes the development of incorporating DIEF in a microfluidic chip to create a comprehensive proteomics tool. Proof-of-concept DIEF experiments have been done previously, so the focus of this work is to explore the capabilities of DIEF. Dynamic isoelectric focusing (DIEF) is a separation technique invented by Dr. Luke Tolley. It is similar to capillary isoelectric focusing except it uses four high voltage electrodes to form a pH gradient instead of only two. The additional two electrodes are able to manipulate the pH gra
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13

Peng, Suili. "Nano/micro particle-based functional composites and applications /." View abstract or full-text, 2007. http://library.ust.hk/cgi/db/thesis.pl?NSNT%202007%20PENG.

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14

Sinha, Ashok. "Characterizing Magnetic Particle Transport for Microfluidic Applications." Diss., Virginia Tech, 2008. http://hdl.handle.net/10919/29266.

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Magnetic particles with active functional groups offer numerous advantages for use in μ-TAS (Micro Total Analytical Systems). The functional site allows chemical binding of the particle with the target species in the fluid sample. Selection of the functional group establishes the target molecule and vice versa under assumptions of highly specific biding. The particles hence act as mobile reaction substrates with high surface to volume ratios owing to their small size. The concept of action at a distance allows their use as agents for separation in microchannels based on relatively simple desi
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15

af, Klinteberg Ludvig. "Fast and accurate integral equation methods with applications in microfluidics." Doctoral thesis, KTH, Numerisk analys, NA, 2016. http://urn.kb.se/resolve?urn=urn:nbn:se:kth:diva-185758.

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This thesis is concerned with computational methods for fluid flows on the microscale, also known as microfluidics. This is motivated by current research in biological physics and miniaturization technology, where there is a need to understand complex flows involving microscale structures. Numerical simulations are an important tool for doing this. The first, and smaller, part of the thesis presents a numerical method for simulating multiphase flows involving insoluble surfactants and moving contact lines. The method is based on an interface decomposition resulting in local, Eulerian grid repr
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Miller, Brian Maxdell. "Bridging the gulf between microfluidics and high throughput industrial applications." Thesis, University of Edinburgh, 2015. http://hdl.handle.net/1842/15793.

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The use of biosensors and microfluidics devices is often limited by constraints in terms of volumetric throughput due to the small dimensions of devices in microfluidics and of expensive and complicated sample preparation steps necessary to ensure the operation of biosensing platforms. This can be due to high initial sample volume with low concentration analytes or complex media matrices from which analytes are extracted. While working to analyse Cryptosporidium presence in drinking water a novel technique was developed. The huge advantages from using a label-free, buffer-free hydrodynamic mec
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17

Rendall, Helen A. "Applications of microfluidics and optical manipulation for photoporation and imaging." Thesis, University of St Andrews, 2015. http://hdl.handle.net/10023/6622.

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Optical manipulation covers a wide range of techniques to guide and trap cells using only the forces exerted by light. Another optical tool is photoporation, the technique of injecting membrane-impermeable molecules using light, which has become an important alternative to other injection techniques. Together they provided sterile tools for manipulation and molecule delivery at the single-cell level. In this thesis, the properties of low Reynolds fluid flows are exploited to guide cells though a femtosecond Bessel beam. This design allows for high-throughput optical injection of cells without
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18

PUNTAMBEKAR, ANIRUDDHA P. "MICROFLUIDIC DISPENSERS BASED ON STRUCTURALLY PROGRAMMABLE MICROFLUIDIC SYSTEMS (sPROMs)AND THEIR APPLICATIONS FOR μTAS". University of Cincinnati / OhioLINK, 2004. http://rave.ohiolink.edu/etdc/view?acc_num=ucin1078290385.

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19

Minnella, Walter Settimo Leonardo. "Development of microfluidic tools for biological applications." Thesis, Bordeaux, 2017. http://www.theses.fr/2017BORD0664.

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Cette thèse traite le développement de dispositifs, basés sur la technologie "laboratoire sur puce"(LOC) qui visent à contrôler l'environnement des systèmes biologiques pour des applications macro et microbiologiques. En effet, les caractéristiques de la microfluidique permettent de manipuler l'environnement cellulaire à un niveau supérieur à celui du degré de contrôle atteignable avec les techniques ordinaires. Dans ce travail de thèse sera explorée la possibilité de profiter de ces fonctions afin de développer des outils de diagnostic peu coûteux et pourtant efficaces. En particulier, on rap
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20

Cavazos, Omar. "Microfluidic-Based Fabrication of Photonic Microlasers for Biomedical Applications." Thesis, University of North Texas, 2019. https://digital.library.unt.edu/ark:/67531/metadc1609066/.

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Optical microlasers have been used in different engineering fields and for sensing various applications. They have been used in biomedical fields in applications such as for detecting protein biomarkers for cancer and for measuring biomechanical properties. The goal of this work is to propose a microfluidic-based fabrication method for fabricating optical polymer based microlasers, which has advantages, over current methods, such us the fabrication time, the contained cost, and the reproducibility of the microlaser's size. The microfluidic setup consisted of microfluidic pumps and a flow focus
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21

Moreira, Raul da Costa. "Implementation of a high resolution optical feedback interferometer for microfluidics applications." Thesis, Toulouse, INPT, 2019. http://www.theses.fr/2019INPT0028.

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Les progrès récents des capteurs interférométriques basés sur la réinjection optique dans une diode laser ont démontré la possibilité de mesurer des débits d’écoulements et des profils de vitesses d’écoulement à l'échelle micrométrique. Ce type de capteurs compacts et intégrés est très prometteur pour un domaine - la microfluidique - qui est en expansion, aux frontières de la physique, de la chimie, de la biologie et du biomédical. Cependant, la mesure du débit ou de la vitesse locale en haute résolution reste un problème très complexe et les capteurs proposés jusqu’à présent n’ont pas fourni
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22

Brodie, Douglas Stuart. "Shear-horizontal surface acoustic wave microfluidics for lab-on-chip applications." Thesis, Heriot-Watt University, 2014. http://hdl.handle.net/10399/2787.

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Surface acoustic wave (SAW) devices based on the piezoelectric principle have been used extensively in telecommunication applications over the last 20 years, but have recently shown promise in the area of biomedical applications due to their efficient micro-fluidic functions and highly sensitive and label-free detection of pathogens, bacteria, cells, DNA and proteins. There are two types of surface acoustic wave modes: i.e., Rayleigh SAW (R-SAW) and shear horizontal SAW (SH-SAW). R-SAW is widely used for microfluidics and sensing in dry conditions, whereas SH-SAW is mainly used for sensing in
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23

Alshehri, Saad. "Proton beam writing of 3D-microstructure for microfluidics and MEMS applications." Thesis, University of Surrey, 2016. http://epubs.surrey.ac.uk/809695/.

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This thesis describes the use of proton beam writing (PBW) for the fabrica- tion for microfluidic and microelectromechanical system (MEMS) devices. In particular, the fabrication of three-dimensional (3D) micro or nanostruc- tures with high aspect ratios is of growing interest in these fields. PBW is the only technique that has the capability to satisfy these requirements while providing full control of the geometrical parameters, such as the sur- face roughness and side wall angle. This technique is a direct microfabri- cation method that employs a focused, energetic (MeV) proton beam to stru
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24

Heo, Jinseok. "Characterization and applications of microfluidic devices based on immobilized biomaterials." Texas A&M University, 2005. http://hdl.handle.net/1969.1/4688.

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Microfluidic biosensors and bioreactors based on immobilized biomaterials are described in this dissertation. Photocrosslinkable hydrogel or polymeric microbeads were used as a supporting matrix for immobilizing E.coli or enzymes in a microfluidic device. This dissertation covers a microfluidic bioreactor based on hydrogel-entrapped E.coli, a microfluidic biosensor based on an array of hydrogel-entrapped enzymes, and a microfluidic bioreactor based on microbead-immobilized enzymes. Hydrogel micropatches containing E.coli were fabricated within a microfluidic channel by in-situ photopolymerizat
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25

Niu, Ye. "Microparticulate Hydrogel Materials Towards Biomedical Applications." The Ohio State University, 2020. http://rave.ohiolink.edu/etdc/view?acc_num=osu1586094812805108.

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26

O'Brien, Sean D. "Electro-osmotic actuation for micropump applications /." Online version of thesis, 2009. http://hdl.handle.net/1850/11634.

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27

Andersson, Helene. "Microfluidic devices for biotechnology and organic chemical applications." Doctoral thesis, Stockholm, 2001. http://urn.kb.se/resolve?urn=urn:nbn:se:kth:diva-3248.

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28

McLean, Jeffrey John. "Interdigital Capacitive Micromachined Ultrasonic Transducers for Microfluidic Applications." Diss., Georgia Institute of Technology, 2004. http://hdl.handle.net/1853/7625.

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The goal of this research was to develop acoustic sensors and actuators for microfluidic applications. To this end, capacitive micromachined ultrasonic transducers (cMUTs) were developed which generate guided acoustic waves in fluid half-spaces and microchannels. An interdigital transducer structure and a phased excitation scheme were used to selectively excite guided acoustic modes which propagate in a single lateral direction. Analytical models were developed to predict the geometric dispersion of the acoustic modes and to determine the sensitivity of the modes to changes in material and geo
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29

Loh, Tzu Liang. "Integrated microfluidics, heaters, and electronic sensors for Lab-on-a-Chip applications." Thesis, Massachusetts Institute of Technology, 2005. http://hdl.handle.net/1721.1/32355.

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Thesis (S.M.)--Massachusetts Institute of Technology, Dept. of Mechanical Engineering, 2005.<br>Includes bibliographical references (leaves 123-125).<br>Microfluidics, microfabricated suspended heaters and electronic field effect sensors have been successfully integrated on a single device chip. This integration enables spatial cycling of as little as 11nL of reagents over different thermally isolated temperature zones, to be coupled with the field effect sensing capabilities, for label-free detection of biomolecules such as DNA. The microfluidic valves provide control over reagent flow, and f
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Wang, Chao. "Microfluidics for particle manipulation : new simulation techniques for novel devices and applications." Thesis, University of Oxford, 2013. http://ora.ox.ac.uk/objects/uuid:8125980e-0603-4425-b0fa-89a4fdfdf464.

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This thesis focuses on fundamental aspects of microfluidic systems and applies relevant findings to innovative designs for advanced particle manipulation applications. Computational Fluid Dynamics (CFD) is adopted for fluid modeling, based on the Finite Volume method. The accuracy of the solutions obtained is confirmed by grid sensitivity analysis and by comparisons with experimental work. Curved microchannel features and the induced Dean flow are studied through a parametric space exploration and simulations. The Lagrange-Euler coupling method – Surface Marker Point methodology – is applied t
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31

Granieri, Lucia. "Droplet-based microfluidics and engineering of tissue plasminogen activator for biomedical applications." Strasbourg, 2009. http://www.theses.fr/2009STRA6162.

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Le phage display est une méthode généralement utilisée pour l'évolution dirigée de protéines, elle permet de produire une immense diversité de variants de protéines exprimés sur la membrane de particules virales. Ces variants de protéines peuvent être sélectionnés soit pour leur affinité de liaison (p. Ex. Les anticorps) soit pour leur activité catalytique (p. Ex. Les enzymes). La sélection d'enzymes pour leur activité catalytique requiert néanmoins l'utilisation de substrats et/ou produits immobilisés, ce qui empêche la sélection de protéines sur plusieurs cycles catalytiques. Le but de ce pr
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32

Ye, Zhou. "Local Flow Manipulation by Rotational Motion of Magnetic Micro-Robots and Its Applications." Research Showcase @ CMU, 2014. http://repository.cmu.edu/dissertations/429.

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Magnetic micro-robots are small robots under 1mm in size, made of magnetic materials, with relatively simple structures and functionalities. Such micro-robots can be actuated and controlled remotely by externally applied magnetic fields, and hence have the potential to access small and enclosed spaces. Most of the existing magnetic micro-robots can operate in wet environments. When the robots are actuated by the applied magnetic field to move inside a viscous liquid, they invoke flow motions around them inside the liquid. The induced flows are relatively local as the velocity of these flows de
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33

Peng, Zhengchun. "Parallel manipulation of individual magnetic microbeads for lab-on-a-chip applications." Diss., Georgia Institute of Technology, 2011. http://hdl.handle.net/1853/39469.

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Many scientists and engineers are turning to lab-on-a-chip systems for cheaper and high throughput analysis of chemical reactions and biomolecular interactions. In this work, we developed several lab-on-a-chip modules based on novel manipulations of individual microbeads inside microchannels. The first manipulation method employs arrays of soft ferromagnetic patterns fabricated inside a microfluidic channel and subjected to an external rotating magnetic field. We demonstrated that the system can be used to assemble individual beads (1-3µm) from a flow of suspended beads into a regular array on
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34

Wu, Jiandong. "Development of microfluidics-based neutrophil migration analysis systems for research and clinical applications." Royal Society of Chemistry, 2013. http://hdl.handle.net/1993/31179.

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Immune cell migration and chemotaxis plays a key role in immune response. Further research to study the mechanisms of immune cell migration and to develop clinical applications requires advanced experimental tools. Microfluidic devices can precisely apply chemical gradient signals to cells, which is advantageous in quantifying cell migratory response. However, most existing microfluidic systems are impractical to use without specialized facilities and research skills, which hinders their broad use in biological and medical research communities. In this thesis, we integrated several new develop
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35

Yao, Peng. "Developing three-dimensional lithography and chemical lithography for applications on micro/nano photonics and electronics." Access to citation, abstract and download form provided by ProQuest Information and Learning Company; downloadable PDF file, 206 p, 2007. http://proquest.umi.com/pqdweb?did=1397913021&sid=11&Fmt=2&clientId=8331&RQT=309&VName=PQD.

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36

Staben, Michelle Elizabeth. "Low-Reynolds-number particle transport in narrow channels for microfluidics and other applications." Diss., Connect to online resource, 2005. http://wwwlib.umi.com/dissertations/fullcit/3178360.

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37

Wang, Yiou. "Numerical Study of Rapid Micromixers for Lab-on-a-chip Applications." University of Akron / OhioLINK, 2007. http://rave.ohiolink.edu/etdc/view?acc_num=akron1185559862.

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38

Li, Hui. "FABRICATION OF MAGNETIC TWO-DIMENSIONAL AND THREE-DIMENSIONAL MICROSTRUCTURES FOR MICROFLUIDICS AND MICROROBOTICS APPLICATIONS." UKnowledge, 2014. http://uknowledge.uky.edu/me_etds/51.

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Micro-electro-mechanical systems (MEMS) technology has had an increasing impact on industry and our society. A wide range of MEMS devices are used in every aspects of our life, from microaccelerators and microgyroscopes to microscale drug-delivery systems. The increasing complexity of microsystems demands diverse microfabrication methods and actuation strategies to realize. Currently, it is challenging for existing microfabrication methods—particularly 3D microfabrication methods—to integrate multiple materials into the same component. This is a particular challenge for some applications, such
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39

Shen, Liuliu [Verfasser], J. M. Bastian Akademischer Betreuer] Etzold, and Markus [Akademischer Betreuer] [Biesalski. "Paper-based Microfluidics for Electrochemical Applications / Liuliu Shen ; J. M. Bastian Etzold, Markus Biesalski." Darmstadt : Universitäts- und Landesbibliothek Darmstadt, 2020. http://nbn-resolving.de/urn:nbn:de:tuda-tuprints-117737.

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Shah, Gaurav Jitendra. "Electrowetting-on-dielectric (EWOD) for biochemical applications particle manipulation for separation in droplet microfluidics /." Diss., Restricted to subscribing institutions, 2008. http://proquest.umi.com/pqdweb?did=1779690391&sid=5&Fmt=2&clientId=48051&RQT=309&VName=PQD.

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Shen, Liuliu [Verfasser], J. M. Bastian [Akademischer Betreuer] Etzold, and Markus [Akademischer Betreuer] Biesalski. "Paper-based Microfluidics for Electrochemical Applications / Liuliu Shen ; J. M. Bastian Etzold, Markus Biesalski." Darmstadt : Universitäts- und Landesbibliothek Darmstadt, 2020. http://d-nb.info/1211478149/34.

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42

Forss, Elin. "Evaluation of OSTE-hybrid materials for acoustophoresis applications." Thesis, KTH, Medicinteknik och hälsosystem, 2020. http://urn.kb.se/resolve?urn=urn:nbn:se:kth:diva-277052.

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This project aimed at exploring new hybrid materials to be used for acoustophoresis applications. Acoustophoresis can be used to manipulate particles inside a microfluidic channel by creating ultrasound standing waves within the channel [1]. This can be used for cell separation [2] or trapping of particles [3]. The intent of this project was to create materials for use in microfluidic channels that would be cheaper and easier to manufacture than those traditionally used, while still having adequate acoustic properties to allow for use in acoustopheresis. This was done by investigating whether
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43

Ladanov, Mikhail. "ZnO Nanostructures: Growth, Characterization and Applications." Scholar Commons, 2012. http://scholarcommons.usf.edu/etd/4353.

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ZnO nanostructures have been investigated for quite a long time. However, only recently they triggered much interest due to advances in materials synthesis and characterization, as well as emerging demand for new nanostructured materials in novel device implementations. A large part of the work was devoted to exploring new methodology for patterning growth sites and controlling nanowires morphology using the deposition methods that are compatible with integrated circuits (IC) processing. Microcontact printing was used to pattern the seeding layer, and, subsequently, ZnO nanowires through a res
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Parra, Cabrera César Alejandro. "Microfluidic devices with integrated biosensors for biomedical applications." Doctoral thesis, Universitat de Barcelona, 2014. http://hdl.handle.net/10803/284758.

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In recent years, the LOC community has focused most of its research in the biomedical and biotechnology fields, due to the need of portable, low power consumption and low cost theranostics microdevices. Some developing countries do not have suitable medical diagnostics technologies and the supply and storage of the reagents is in many cases limited as well as the access to energy. Furthermore, developed countries are experimenting population aging needing novel low cost efficient disease-screening technologies. The introduction of LOC and microfluidics allow the integration of complex function
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Thibault, Derek M. "Applications of droplet-based microfluidics to identify genetic mechanisms behind stress responses in bacterial pathogens." Thesis, Boston College, 2016. http://hdl.handle.net/2345/bc-ir:106985.

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Thesis advisor: Michelle Meyer<br>The primary bacterial targets for most antibiotics are well known. To survive the stress of an antibiotic a bacterium must decrease the antibiotic to target binding ratio to escape from harmful effects. This can occur through a number of different functions including down-regulation of the target, mutation of the binding site on the target, and decreasing the intake or increasing the efflux of the antibiotic. However, it is becoming more evident that an antibiotic stress response influences more than just the primary target, and that a wave of secondary respon
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46

Gauntt, Stephen Byron. "Micro-chamber filling experiments for validation of macro models with applications in capillary driven microfluidics." [College Station, Tex. : Texas A&M University, 2007. http://hdl.handle.net/1969.1/ETD-TAMU-2538.

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47

Ren, Yundong. "Specially Shaped Optical Fiber Probes: Understanding and Their Applications in Integrated Photonics, Sensing, and Microfluidics." Digital WPI, 2019. https://digitalcommons.wpi.edu/etd-dissertations/569.

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Thanks to their capability of transmitting light with low loss, optical fibers have found a wide range of applications in illumination, imaging, and telecommunication. However, since the light guided in a regular optical fiber is well confined in the core and effectively isolated from the environment, the fiber does not allow the interactions between the light and matters around it, which are critical for many sensing and actuation applications. Specially shaped optical fibers endow the guided light in optical fibers with the capability of interacting with the environment by modifying part of
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48

Mohamedi, Graciela. "Engineering the surface properties of microbubbles for biomedical applications." Thesis, University of Oxford, 2014. http://ora.ox.ac.uk/objects/uuid:e68f2010-19b6-45af-b238-da8e2d29b270.

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Surfactant coated microbubbles are widely used as contrast agents (UCA) in medical ultrasound imaging, due to their high echogenicity and non-linear response to acoustic excitation. Controlling the stability of microbubbles in vivo represents a considerable challenge. Understanding the characteristics of the bubble surface and how they change with production method, composition and environment is key to addressing this problem. The aim of this thesis is to investigate viscosity, bubble dissolution, and acoustic response as functions of their composition, manufacturing method and environment. B
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He, Yingning. "Lateral porous silicon membranes for planar microfluidic applications." Thesis, Toulouse 3, 2016. http://www.theses.fr/2016TOU30255/document.

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Abstract:
Les laboratoires sur puce visent à miniaturiser et à intégrer les fonctions couramment utilisées dans les laboratoires d'analyse afin de cibler des applications en santé avec un impact prometteur sur le diagnostic médical au lit du patient. Les membranes poreuses sont d'un grand intérêt pour la préparation et l'analyse d'échantillon sur puce car elles permettent la séparation par taille/charge de molécules, mais également leur pré-concentration. Parmi les matériaux disponibles pour constituer des membranes poreuses, le silicium poreux présente de nombreux avantages tels que le contrôle précis
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50

Tang, Qi, Min Liang, Yi Lu, et al. "Microfluidic Devices for Terahertz Spectroscopy of Live Cells Toward Lab-on-a-Chip Applications." MDPI AG, 2016. http://hdl.handle.net/10150/614745.

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Abstract:
THz spectroscopy is an emerging technique for studying the dynamics and interactions of cells and biomolecules, but many practical challenges still remain in experimental studies. We present a prototype of simple and inexpensive cell-trapping microfluidic chip for THz spectroscopic study of live cells. Cells are transported, trapped and concentrated into the THz exposure region by applying an AC bias signal while the chip maintains a steady temperature at 37 degrees C by resistive heating. We conduct some preliminary experiments on E. coli and T-cell solution and compare the transmission spect
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