Academic literature on the topic 'Microfluidics paper-based analytical device'

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Journal articles on the topic "Microfluidics paper-based analytical device"

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Coltro, Wendell. "Paper-based microfluidics: What can we expect?" Brazilian Journal of Analytical Chemistry 9, no. 37 (2022): 11–13. http://dx.doi.org/10.30744/brjac.2179-3425.point-of-view-wktcoltro.n37.

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In the last three decades, the scientific community has observed exponential growth in the development of microfluidic platforms and their use for applications in different fields. The noticeable advances are attributed to the advantages provided by miniaturization.1 In summary, the downscaling of analytical devices has offered attractive features, including reduced consumption of samples and reagents, short analysis time, and minimal waste generation. In addition, the possibility to perform multiplexed assays in portable devices without bulky instrumentation is another attractive feature that
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Catalan-Carrio, Raquel, Tugce Akyazi, Lourdes Basabe-Desmonts, and Fernando Benito-Lopez. "Predicting Dimensions in Microfluidic Paper Based Analytical Devices." Sensors 21, no. 1 (2020): 101. http://dx.doi.org/10.3390/s21010101.

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The main problem for the expansion of the use of microfluidic paper-based analytical devices and, thus, their mass production is their inherent lack of fluid flow control due to its uncontrolled fabrication protocols. To address this issue, the first step is the generation of uniform and reliable microfluidic channels. The most common paper microfluidic fabrication method is wax printing, which consists of two parts, printing and heating, where heating is a critical step for the fabrication of reproducible device dimensions. In order to bring paper-based devices to success, it is essential to
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Meredith, Nathan A., Casey Quinn, David M. Cate, Thomas H. Reilly, John Volckens, and Charles S. Henry. "Paper-based analytical devices for environmental analysis." Analyst 141, no. 6 (2016): 1874–87. http://dx.doi.org/10.1039/c5an02572a.

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Juang, Yi-Je, and Shu-Kai Hsu. "Fabrication of Paper-Based Microfluidics by Spray on Printed Paper." Polymers 14, no. 3 (2022): 639. http://dx.doi.org/10.3390/polym14030639.

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Since the monumental work conducted by Whitesides et al. in 2007, research and development of paper-based microfluidics has been widely carried out, with its applications ranging from chemical and biological detection and analysis, to environmental monitoring and food-safety inspection. Paper-based microfluidics possesses several competitive advantages over other substrate materials, such as being simple, inexpensive, power-free for fluid transport, lightweight, biodegradable, biocompatible, good for colorimetric tests, flammable for easy disposal of used paper-based diagnostic devices by inci
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Ozer, Tugba, Catherine McMahon, and Charles S. Henry. "Advances in Paper-Based Analytical Devices." Annual Review of Analytical Chemistry 13, no. 1 (2020): 85–109. http://dx.doi.org/10.1146/annurev-anchem-061318-114845.

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Microfluidic paper-based analytical devices (μPADs) are the newest generation of lab-on-a-chip devices and have made significant strides in both our understanding of fundamental behavior and performance characteristics and expansion of their applications. μPADs have become useful analytical techniques for environmental analysis in addition to their more common application as medical point-of-care devices. Although the most common method for device fabrication is wax printing, numerous other techniques exist and have helped address factors ranging from solvent compatibility to improved device f
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Lim, Jafry, and Lee. "Fabrication, Flow Control, and Applications of Microfluidic Paper-Based Analytical Devices." Molecules 24, no. 16 (2019): 2869. http://dx.doi.org/10.3390/molecules24162869.

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Paper-based microfluidic devices have advanced significantly in recent years as they are affordable, automated with capillary action, portable, and biodegradable diagnostic platforms for a variety of health, environmental, and food quality applications. In terms of commercialization, however, paper-based microfluidics still have to overcome significant challenges to become an authentic point-of-care testing format with the advanced capabilities of analyte purification, multiplex analysis, quantification, and detection with high sensitivity and selectivity. Moreover, fluid flow manipulation for
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Channon, Robert B., Michael P. Nguyen, Alexis G. Scorzelli, et al. "Rapid flow in multilayer microfluidic paper-based analytical devices." Lab on a Chip 18, no. 5 (2018): 793–802. http://dx.doi.org/10.1039/c7lc01300k.

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Multilayer paper devices are used to generate fast flow rates (1.56 cm s<sup>−1</sup>) which are 145-fold quicker than classical single-layer paper device designs. These self-pumping devices are demonstrated for the sequential injection stripping analysis of cadmium.
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Li, Qi, Xingchen Zhou, Qian Wang, Wenfang Liu, and Chuanpin Chen. "Microfluidics for COVID-19: From Current Work to Future Perspective." Biosensors 13, no. 2 (2023): 163. http://dx.doi.org/10.3390/bios13020163.

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Spread of coronavirus disease 2019 (COVID-19) has significantly impacted the public health and economic sectors. It is urgently necessary to develop rapid, convenient, and cost-effective point-of-care testing (POCT) technologies for the early diagnosis and control of the plague’s transmission. Developing POCT methods and related devices is critical for achieving point-of-care diagnosis. With the advantages of miniaturization, high throughput, small sample requirements, and low actual consumption, microfluidics is an essential technology for the development of POCT devices. In this review, acco
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Mentele, Mallory M., Josephine Cunningham, Kirsten Koehler, John Volckens, and Charles S. Henry. "Microfluidic Paper-Based Analytical Device for Particulate Metals." Analytical Chemistry 84, no. 10 (2012): 4474–80. http://dx.doi.org/10.1021/ac300309c.

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Kugimiya, Akimitsu, Akane Fujikawa, Xiao Jiang, et al. "Microfluidic Paper-Based Analytical Device for Histidine Determination." Applied Biochemistry and Biotechnology 192, no. 3 (2020): 812–21. http://dx.doi.org/10.1007/s12010-020-03365-z.

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Dissertations / Theses on the topic "Microfluidics paper-based analytical device"

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Murdock, Richard C. "Development of Microfluidic Paper-based Analytical Devices for Point-of-Care Human Physiological and Performance Monitoring." University of Cincinnati / OhioLINK, 2015. http://rave.ohiolink.edu/etdc/view?acc_num=ucin1439308025.

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Klasner, Scott A. "Novel capillary and microfluidic devices for biological analyses." Diss., Manhattan, Kan. : Kansas State University, 2010. http://hdl.handle.net/2097/3747.

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Kripalani, Rishi A. "Novel Integration of Conductive-ink Circuitry with a Paper-based Microfluidic Battery as an All-printed Sensing Platform." DigitalCommons@CalPoly, 2016. https://digitalcommons.calpoly.edu/theses/1694.

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The addition of powered components for active assays into paper-based analytical devices opens new opportunities for medical and environmental analysis in resource-limited applications. Current battery designs within such devices have yet to adopt a ubiquitous circuitry material, necessitating investigation into printed circuitry for scalable platforms. In this study, a microfluidic battery was mated with silver-nanoparticle conductive ink to prototype an all-printed sensing platform. A multi-layer, two-cell device was fabricated, generating 200 μA of direct electrical current at 2.5 V sustain
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Liu, Cheyenne H. "Development and Characterization of Reagent Pencils for Microfluidic Paper Based Analytical Devices." DigitalCommons@CalPoly, 2016. https://digitalcommons.calpoly.edu/theses/1639.

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Microfluidic paper based analytical devices (microPADs) are a novel platform for point of care (POC) diagnostics. Limitations of reagent shelf life have been overcome with the introduction of reagent pencils as a method for solid-based reagent deposition. While useful, little work has been reported on the characterization and optimization of reagent pencils. Herein, an investigation on reagent pencil composition and efficiency is conducted via colorimetric release profile tests utilizing an erioglaucine disodium salt that yields a quantifiable blue colored product in the presence of water. Wit
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Nguyen, Vina, and Vina Nguyen. "Microfluidic Paper Analytic Device for Assessment of Blood Coagulation." Thesis, The University of Arizona, 2017. http://hdl.handle.net/10150/624139.

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Monitoring blood coagulation while a patient is on cardiopulmonary bypass (CPB) is critical in preventing clots from arising in the bypass machine and consequently being sent into the patient’s bloodstream. Current methods used to monitor blood coagulation such as Activated Clotting Time (ACT) yield results that do not correlate coagulation time to heparin or protamine dosage and will typically take at least 400 s to yield a result that is safe to initiate bypass. Microfluidic paper-based analytical devices (μPAD) are advanced sensors based on a wide range of recently developed techniques for
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Mitchell, Haydn Thomas. "AN INVESTIGATION OF POLY(N-ISOPROPYLACRYLAMIDE) FOR APPLICATIONS WITH MICROFLUIDIC PAPER-BASED ANALYTICAL DEVICES." DigitalCommons@CalPoly, 2014. https://digitalcommons.calpoly.edu/theses/1248.

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N,N′-methylenebisacrylamide-crosslinked poly(N-isopropylacrylamide), also known as P(NIPAM), was developed as a fluid delivery system for use with microfluidic paper-based analytical devices (microPADs). MicroPADs are postage-stamp-sized devices made out of paper that can be used as platforms for low-cost, simple-to-use point-of-care diagnostic assays. P(NIPAM) is a thermally responsive polymer that absorbs aqueous solutions at room temperature and will expel the solutions to microPADs when heated. The fluid delivery characteristics of P(NIPAM) were assessed, and P(NIPAM) was able to deliver m
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Schultz, Spencer A. "An Investigation into the Use of Polymer Bound Boronic Acid for Glucose Detection in Paper Based Microfluidic Devices." DigitalCommons@CalPoly, 2016. https://digitalcommons.calpoly.edu/theses/1611.

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Paper Based Microfluidic Devices (microPADs) are a new platform for point-of-care diagnostic assays for use in resource-limited settings. These devices rely typically on enzymatic assays to produce their results, which makes them susceptible to degradation when exposed to extreme environmental conditions such as high temperature. In order to overcome this limitation, this research project focused on investigating the use of polymers instead of enzymes to detect analytes on microPADs. Polymer-bound boronic acid, a glucose and pH sensitive polymer, was incorporated into microPADs in order to dev
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Busin, Valentina. "The development of microfluidic paper-based analytical devices for point-of-care diagnosis of sheep scab." Thesis, Heriot-Watt University, 2017. http://hdl.handle.net/10399/3263.

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The recent growing interest and development of microfluidic paper-based analytical devices (μPADs) for point-of-care (POC) testing in human health in low-resource settings has great potential for the exploitation of these technologies in animal disease diagnosis. Sheep scab is a highly infectious, widespread and notifiable disease of sheep, which poses major economic and welfare concerns for the UK farming industry. The possibility of diagnosing sheep scab at the POC is, consequently, very important to controlling this disease. The overall aim of this project was, therefore, to develop μPADs b
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Chaplan, Cory A. "Stabilization of Horseradish Peroxidase Using Epoxy Novolac Resins for Applications with Microfluidic Paper-Based Analytical Devices." DigitalCommons@CalPoly, 2014. https://digitalcommons.calpoly.edu/theses/1252.

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Microfluidic paper-based analytical devices (microPADs) are an emerging platform for point-of-care diagnostic tests for use by untrained users with potential applications in healthcare, environmental monitoring, and food safety. These devices can be developed for a multitude of different tests, many of which employ enzymes as catalysts. Without specialized treatment, some enzymes tend to lose their activity when stored on microPADs within 48 hours, which is a major hurdle for taking these types of devices out of the laboratory and into the real world. This work focused on the development of si
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Zangheri, Martina <1987&gt. "Ultrasensitive chemiluminescence bioassays based on microfluidics in miniaturized analytical devices." Doctoral thesis, Alma Mater Studiorum - Università di Bologna, 2015. http://amsdottorato.unibo.it/6999/1/Zangheri_Martina_tesi.pdf.

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The activity carried out during my PhD was principally addressed to the development of portable microfluidic analytical devices based on biospecific molecular recognition reactions and CL detection. In particular, the development of biosensors required the study of different materials and procedures for their construction, with particular attention to the development of suitable immobilization procedures, fluidic systems and the selection of the suitable detectors. Different methods were exploited, such as gene probe hybridization assay or immunoassay, based on different platform (functionaliz
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Books on the topic "Microfluidics paper-based analytical device"

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Krishnendu, Chakrabarty, and Zeng Jun, eds. Design automation methods and tools for microfluidics-based biochips. Springer, 2006.

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(Editor), Krishnendu Chakrabarty, and Jun Zeng (Editor), eds. Design Automation Methods and Tools for Microfluidics-Based Biochips. Springer, 2006.

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Book chapters on the topic "Microfluidics paper-based analytical device"

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Handa, Shristi, Vibhav Katoch, and Bhanu Prakash. "Microfluidic Paper-Based Analytical Devices for Glucose Detection." In Advanced Microfluidics-Based Point-of-Care Diagnostics. CRC Press, 2022. http://dx.doi.org/10.1201/9781003033479-3.

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Seetasang, Sasikarn, and Takashi Kaneta. "Analytical Devices with Instrument-Free Detection Based on Paper Microfluidics." In Advanced Microfluidics-Based Point-of-Care Diagnostics. CRC Press, 2022. http://dx.doi.org/10.1201/9781003033479-10.

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Wagh, Mrunali D., S. B. Puneeth, Subhendu Kumar Sahoo, and Sanket Goel. "Wax-Printed Microfluidic Paper Analytical Device for Viscosity-Based Biosensing in a 3D Printed Image Analysis Platform." In Microactuators, Microsensors and Micromechanisms. Springer International Publishing, 2022. http://dx.doi.org/10.1007/978-3-031-20353-4_26.

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Shi, Zhuan Zhuan, Yao Lu, and Ling Yu. "Microfluidic Paper-Based Analytical Devices for Point-of-Care Diagnosis." In Next Generation Point-of-care Biomedical Sensors Technologies for Cancer Diagnosis. Springer Singapore, 2017. http://dx.doi.org/10.1007/978-981-10-4726-8_16.

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Vishwakarma, Niraj K., Parul Chaurasia, Pranjal Chandra, and Sanjeev Kumar Mahto. "Microfluidics Devices as Miniaturized Analytical Modules for Cancer Diagnosis." In Advanced Microfluidics-Based Point-of-Care Diagnostics. CRC Press, 2022. http://dx.doi.org/10.1201/9781003033479-9.

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Matson, Dean W., Peter M. Martin, Wendy D. Bennett, Dean E. Kurath, Yuehe Lin, and Donald J. Hammerstrom. "Fabrication Processes for Polymer-Based Microfluidic Analytical Devices." In Micro Total Analysis Systems ’98. Springer Netherlands, 1998. http://dx.doi.org/10.1007/978-94-011-5286-0_88.

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Oliveira, Karoliny Almeida, Fabrício Ribeiro de Souza, Cristina Rodrigues de Oliveira, Lucimeire Antonelli da Silveira, and Wendell Karlos Tomazelli Coltro. "Microfluidic Toner-Based Analytical Devices: Disposable, Lightweight, and Portable Platforms for Point-of-Care Diagnostics with Colorimetric Detection." In Methods in Molecular Biology. Springer New York, 2014. http://dx.doi.org/10.1007/978-1-4939-2172-0_6.

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Giri, Basant. "Determination of Nitrite Ions in Water Using Paper Analytical Device." In Laboratory Methods in Microfluidics. Elsevier, 2017. http://dx.doi.org/10.1016/b978-0-12-813235-7.00013-1.

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Faheem, Aroosha, and Stefano Cinti. "Advanced techniques for manufacturing paper-based microfluidic analytical devices." In Microfluidic Biosensors. Elsevier, 2023. http://dx.doi.org/10.1016/b978-0-12-823846-2.00009-2.

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Linnes, Jacqueline C., and Elizabeth Phillips. "Printed Wax-Ink Valves for Multistep Assays in Paper Analytical Devices." In Diagnostic Devices with Microfluidics. CRC Press, 2017. http://dx.doi.org/10.1201/9781315154442-4.

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Conference papers on the topic "Microfluidics paper-based analytical device"

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Lu, Chuan-Pin, Bo-Xian Guo, Zi-Qing Fang, and Shu-Chiang Chung. "The development of image base, portable microfluidic paper-based analytical device." In 2015 International Conference on Orange Technologies (ICOT). IEEE, 2015. http://dx.doi.org/10.1109/icot.2015.7498497.

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Zhang, Haipeng, Danielle Barmore, and Sangjin Ryu. "Flow Characterization of Microfluidic Paper-Based Analytical Devices With Hollow Channels." In ASME-JSME-KSME 2019 8th Joint Fluids Engineering Conference. American Society of Mechanical Engineers, 2019. http://dx.doi.org/10.1115/ajkfluids2019-5502.

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Abstract Microfluidic paper-based analytical devices (μPADs) are cost-effective point-of-care diagnostic devices. μPADs consist of porous filter paper patterned with hydrophobic solid ink barriers to create flow channels. Because a liquid sample flows through the paper channel driven by capillary force, the resultant flow is usually slow. To overcome this limitation, a hollow channel can be added to a μPAD to increase the flow speed significantly. The liquid flow through the hollow channel is known to be driven by a pressure difference between the inlet and outlet of the device. Accordingly, t
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Blume, Steffen O. P., Michael J. Schertzer, Ridha Ben Mrad, and Pierre E. Sullivan. "Analytical Models to Determine the Electric Field Characteristics of a Multi-Electrode Impedimetric Immunosensor in a Digital Microfluidic Device." In ASME 2014 International Mechanical Engineering Congress and Exposition. American Society of Mechanical Engineers, 2014. http://dx.doi.org/10.1115/imece2014-37571.

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The level of integration of digital microfluidics is continually increasing to include the system path from fluid manipulation and transport, on to reagent preparation, and finally reaction detection. Digital microfluidics therefore has the capability to encompass all steps of common biochemical protocols. Reported here is a set of analytical models for the design of a coplanar interdigitated multi-electrode array to be used as an impedimetric immunosensor in a digital microfluidic device for on-chip chemical reaction detection. The models are based on conformal mapping techniques, and are com
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McCracken, Katherine E., Trinny Tat, Veronica Paz, Kelly A. Reynolds, and Jeong-Yeol Yoon. "Immunoagglutinated particle rheology sensing on a microfluidic paper-based analytical device for pathogen detection." In 2017 Spokane, Washington July 16 - July 19, 2017. American Society of Agricultural and Biological Engineers, 2017. http://dx.doi.org/10.13031/aim.201701190.

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Luo, L., J. Qi, L. Zhang, D. Deng, and Y. Li. "P1DH.2 - Paper-Based Microfluidic Analytical Device Based on Molecularly Imprinted Polymer for Detection of Carcinoembryonic Antigen." In 17th International Meeting on Chemical Sensors - IMCS 2018. AMA Service GmbH, Von-Münchhausen-Str. 49, 31515 Wunstorf, Germany, 2018. http://dx.doi.org/10.5162/imcs2018/p1dh.2.

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Zamri, N. L., та M. H. M. Salleh. "Investigation of liquid flow interaction on wax and cut channel paper-based microfluidic analytical device (μPAD)". У 7th Brunei International Conference on Engineering and Technology 2018 (BICET 2018). Institution of Engineering and Technology, 2018. http://dx.doi.org/10.1049/cp.2018.1569.

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Cai, Tianyu, Sixuan Duan, Hao Fu, et al. "A Paper-Based Microfluidic Analytical Device with A Highly Integrated On-Chip Valve For Autonomous ELISA." In 2022 IEEE 35th International Conference on Micro Electro Mechanical Systems Conference (MEMS). IEEE, 2022. http://dx.doi.org/10.1109/mems51670.2022.9699652.

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Moon, Hyejin, Praveen Kunchala, Yasith Nanayakkara, and Daniel W. Armstrong. "Liquid-Liquid Extraction Based on Digital Microfluidics." In ASME 2009 7th International Conference on Nanochannels, Microchannels, and Minichannels. ASMEDC, 2009. http://dx.doi.org/10.1115/icnmm2009-82268.

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Liquid-liquid extraction techniques are one of the major tools in chemical engineering, analytical chemistry, and biology, especially in a system where two immiscible liquids have an interface solutes exchange between the two liquid phases along the interface up to a point where the concentration ratios in the two liquids reach their equilibrium values [1]. In this paper, we propose to use room temperature ionic liquid (RTIL) as a second liquid phase for extraction, which forms immiscible interface with aqueous solutions. We demonstrate liquid-liquid extraction with the EWOD digital microfluid
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Rahman, M. Shafiqur, and Uttam K. Chakravarty. "Characterizations of the Paper-Based Microfluidic Devices Used for Detecting Fentanyl and Related Synthetic Opioids." In ASME 2019 International Mechanical Engineering Congress and Exposition. American Society of Mechanical Engineers, 2019. http://dx.doi.org/10.1115/imece2019-11581.

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Abstract The design and analysis of a paper-based microfluidic analytical device (μPAD) are presented in this paper for the detection of fentanyl and related synthetic opioids. Fentanyl, a synthetic opioid, is an extremely fast-acting synthetic narcotic analgesic having a high potency of approximately 100 to 200 times that of morphine. Detection of fentanyl can be done by colorimetric assays, i.e., spot tests with paper strips and μPADs which offer speed, simplicity of operation, portability, and affordability. The microfluidic behavior of liquid specimen and paper in the μPADs and test strips
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Yuwono, Rio Akbar, Mokhammad Fahmi Izdiharruddin, and Ruri Agung Wahyuono. "Integrated ZnO nanoparticles on paper-based microfluidic: toward efficient analytical device for glucose detection based on impedance and FTIR measurement." In Second International Seminar on Photonics, Optics, and Its Applications (ISPhOA 2016), edited by Agus M. Hatta and Aulia M. T. Nasution. SPIE, 2016. http://dx.doi.org/10.1117/12.2243827.

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