Academic literature on the topic 'Micromeritic studies'

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Journal articles on the topic "Micromeritic studies"

1

OZYAZICI, M. "Micromeritic studies on nicardipine hydrochloride microcapsules." International Journal of Pharmaceutics 138, no. 1 (1996): 25–35. http://dx.doi.org/10.1016/0378-5173(96)04516-4.

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2

Sande, T. A., F. J. Sayyad, A. V. Patil, and D. D. Mohite. "FORMULATION AND CHARACTERIZATION OF RITONAVIR LOADED PRONIOSOMES FOR ORAL DRUG DELIVERY." INDIAN DRUGS 54, no. 08 (2017): 46–53. http://dx.doi.org/10.53879/id.54.08.11045.

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Proniosomes of ritonavir were prepared by slurry method using Span 60, maltodextrin and cholesterol. The ratio of concentration of Span 60 to cholesterol was altered while keeping concentration of drug and maltodextrin constant. Prepared formulations were studied for micromeritic properties, entrapment efficiency, particle size, surface morphology and in vitro drug release. Micromeritic properties of all formulations increased as compared to drug and carrier alone. Entrapment efficiency was observed greater than 90 % and drug release was found to be sustained for upto 12 hours in case of all f
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3

Saritha, Damineni, Penjuri Subhash Chandra Bose, Poreddy Srikanth Reddy, Grandhi Madhuri, and Ravouru Nagaraju. "Improved dissolution and micromeritic properties of naproxen from spherical agglomerates: preparation, in vitro and in vivo characterization." Brazilian Journal of Pharmaceutical Sciences 48, no. 4 (2012): 667–76. http://dx.doi.org/10.1590/s1984-82502012000400010.

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Naproxen, an anti-inflammatory drug, exhibits poor aqueous solubility, which limits the pharmacological effects. The present work was carried out to study the effect of agglomeration on micromeritic properties and dissolution. Naproxen agglomerates were prepared by using a three solvents system composed of acetone (good solvent), water (non-solvent) and dichloromethane (bridging liquid). Differential Scanning Calorimetry (DSC) results showed no change in the drug after crystallization process. X-Ray Powder Diffraction (XRPD) studies showed the sharp peaks are present in the diffractograms of s
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Gupta, Venkadari, Srinivas Mutalik, Madhobhai Patel, and Girish Jani. "Spherical crystals of celecoxib to improve solubility, dissolution rate and micromeritic properties." Acta Pharmaceutica 57, no. 2 (2007): 173–84. http://dx.doi.org/10.2478/v10007-007-0014-8.

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Spherical crystals of celecoxib to improve solubility, dissolution rate and micromeritic propertiesCelecoxib spherical agglomerates were prepared with polyvinylpyrrolidone (PVP) using acetone, water and chloroform as solvent, non-solvent and bridging liquid, respectively. The agglomerates were characterized by differential scanning calorimetry (DSC), X-ray diffraction (XRD), IR spectroscopic studies and scanning electron microscopy (SEM). The IR spectroscopy and DSC results indicated the absence of any interactions between drug and additives. XRD studies showed a decrease in crystallinity in a
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Nijhawan, Monika, Rajeswari Aleti, Sailaja Gunnam, and Sneha Nawale. "SPHERICAL AGGLOMERATION OF TELMISARTAN - AN APPROACH TO IMPROVE PHYSICOCHEMICAL PROPERTIES." INDIAN DRUGS 61, no. 08 (2024): 38–43. http://dx.doi.org/10.53879/id.61.08.14698.

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The study explains the preparation of spherical agglomerates (SA) of telmisartan (TLS), a BCS class II drug used to improve it’s physicochemical and bulk properties. Drugs of this class could potentially exhibit dissolution rate limited absorption. TLS spherical agglomerates were designed using hydrophilic polymer (PVP K-30), dimethyl formamide (DMF), water and ethyl acetate (bridging liquid) by solvent change method and evaluated for micromeritic properties. The SA were characterized by particle size determination, FTIR, PXRD and SEM. The results of micromeritic studies indicated that SA show
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Umoh, Romanus A., Imoh I. Johnny, Nsima A. Andy, Anwanabasi E. Udoh, Trust E. Ekpo, and Gabriel U. Ashibeshi. "Micromorphological and Pharmacognostic Studies of Mussaenda philippica L. Flower." Journal of Complementary and Alternative Medical Research 23, no. 4 (2023): 1–11. http://dx.doi.org/10.9734/jocamr/2023/v23i4483.

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Mussaenda philippica Linn. belongs to the sub-family Ixoroideae which belongs to the family Rubiaceae. The aim of this study was to employ the quality control parameters in the evaluation of flowers of M. philippica L. The flowers were collected, identified, air dried and pulverized. Standard procedures were carried out to obtain microscopic features of the fresh and powdered samples, micromeritic, chemomicroscopy, flourescence properties, soluble-extractive values, moisture content and ash values. The results of the microscopic studies using the fresh and powdered flower revealed the presence
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Saikia, Trideep, Jonab Ali, and Biswajit Das. "ISOLATION AND CHARECTERIZATION OF TAMARIND SEED POLYSACCHARIDES–A NATURAL RELEASE RETARDANT." International Journal of Current Pharmaceutical Research 9, no. 4 (2017): 114. http://dx.doi.org/10.22159/ijcpr.2017v9i4.20972.

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Objective: The main objective was to isolate and characterise a naturally obtain polysaccharides which have the property to formulate sustain release product.Methods: Tamarind Seed Polysaccharides (TSP) was isolated from seed of Tamarindus indica by crushed the seed into powder and boiled with water at 45 °C to extract the polysaccharides. After boiling for 12 h the supernatant liquids were collected and stored in cool place. After the liquids become cooled acetone was added and freeze at-40 °C. Freeze materials then lyophilized to extract out the Tamarind seed polysaccharides. After that poly
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8

Venkateswarlu, Kambham. "Evaluation of glibenclamide microspheres for sustained release." Journal of Pharmacy & Pharmacognosy Research 5, no. 1 (2017): 78–87. http://dx.doi.org/10.56499/jppres16.156_5.2.78.

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Context: Sustained release drug delivery systems are more preferred than the conventional drug delivery systems due to its enhanced bioavailability and patient compliance. Earlier studies reported on glibenclamide (GBCM) were not clear and hence, the step has been taken to explore the sustained release drug delivery system of GBCM. Aims: To evaluate the sustained release microspheres obtained of GBCM. Methods: Microspheres were prepared by ionic gelation method using the polymers like Eudragit RS 100 and xanthan gum. Polymers can sustain the drug release from microspheres. The prepared microsp
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9

Siddheshwar, Suhas S., Kiran R. Dushing, and Someshwar D. Mankar. "FORMULATION AND EVALUATION OF CEFDITOREN PIVOXIL GRANULES FOR ORAL USE." INDIAN DRUGS 61, no. 12 (2024): 37–42. https://doi.org/10.53879/id.61.12.14845.

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Cefditoren pivoxil is used in the treatment of various bacterial infections. It exhibits a strong bitter taste on oral administration. Thus, there is a need that the bitter taste of cefditoren pivoxil should be minimized to such an extent that the oral administration of cefditoren pivoxil would be palatable to patients. The study reported here aimed to develop cefditoren pivoxil granules by dry granulation technique, characterize them for micromeritic properties, to mask the bitterness of the drug and undertake in vitro drug release studies. The pre-formulation studies were carried out using H
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10

Abali, S. Okorie, C. Ekenna Ifeoma, and Faithfulness Ochen. "Formulation and Characterization of Extended-Release Nevirapine Solid Dispersions Running Title: Extended Release Nevirapine Solid Dispersions." International Journal of Innovative Science and Research Technology 7, no. 3 (2022): 588–94. https://doi.org/10.5281/zenodo.6406164.

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The bioavailability of a drug is usually determined by its aqueous solubility and lipid permeability. Nevirapine is an antiretroviral drug that belongs to the BCS II with poor solubility but high permeability. This study was carried out to improve the dissolution of nevirapine and also to formulate extended-release nevirapine tablets. Nevirapine: PEG 4000 were combined in different ratios to produce physical mixtures and solid dispersions. Micromeritics studies were carried out on the particles of the solid dispersions and the physical mixtures. These physical mixtures and solid dispersions we
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