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Journal articles on the topic 'Micromeritics'

Author: Grafiati

Published: 4 June 2021

Last updated: 1 February 2022

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1

Himawan, A., N. J. N. Djide, M. Mudjahid, A. D. I. Lukita, A. Arjuna, and Aliyah. "Physicochemical and Micromeritics Properties of Ketoprofen-Tartaric Acid Binary System." Journal of Physics: Conference Series 1341 (October 2019): 072004. http://dx.doi.org/10.1088/1742-6596/1341/7/072004.

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Paramakrishnan, N., S. Jha, and K. Jayaram Kumar. "Effect of carboxymethylation on physicochemical, micromeritics and release characteristics of Kyllinga nemoralis starch." International Journal of Biological Macromolecules 92 (November 2016): 543–49. http://dx.doi.org/10.1016/j.ijbiomac.2016.07.039.

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Kedia, Kishori, and Sarika Wairkar. "Improved micromeritics, packing properties and compressibility of high dose drug, Cycloserine, by spherical crystallization." Powder Technology 344 (February 2019): 665–72. http://dx.doi.org/10.1016/j.powtec.2018.12.068.

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Ayon, Navid Jubaer, Ikramul Hasan, Md Shfiqul Islam, and Md Selim Reza. "Preparation and characterization of Gliclazide incorporated Cellulosic Microspheres: studies on drug release, compatibility and micromeritics." Dhaka University Journal of Pharmaceutical Sciences 13, no. 2 (2015): 149–66. http://dx.doi.org/10.3329/dujps.v13i2.21893.

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Polymeric microspheres of gliclazide were prepared to provide sustained release delivery of gliclazide to aid in continuous therapy with high margin of safety. Gliclazide was microencapsulated with different polymers namely HPMC K100LV, Ethocel (20 cps) and HPMC K100M by emulsion solvent evaporation technique using acetone as internal phase and liquid paraffin as external phase. Seventeen formulations were prepared using different drug loading and polymeric ratio of which nine formulations were prepared by a 32 full factorial design. Each formulation was evaluated for flow properties, particle

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Viswanathan, Chelakara L., Sushrut K. Kulkarni, and Dhanashri R. Kolwankar. "Spherical agglomeration of mefenamic acid and nabumetone to improve micromeritics and solubility: A technical note." AAPS PharmSciTech 7, no. 2 (2006): E122—E125. http://dx.doi.org/10.1208/pt070248.

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Ma, Cheng, Wenhao Wang, Zhengwei Huang, et al. "Effect of the cargo lipophilicity on powder micromeritics properties of drug-loaded solid lipid microparticles." Journal of Drug Delivery Science and Technology 51 (June 2019): 614–20. http://dx.doi.org/10.1016/j.jddst.2019.03.025.

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Pryszcz, Adrian, Barbora Grycová, Ivan Koutník, and Veronika Blahůšková. "Characterization of Tar Deposits, Extraction and Sorption Properties." GeoScience Engineering 62, no. 2 (2016): 1–4. http://dx.doi.org/10.1515/gse-2016-0010.

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Abstract The main goal of this paper was to characterize and find a useful solution for the decomposition of tar deposits. For the experimental part, tar deposits, formed by polymerization and condensation reactions, were chosen from a storage tank for tars. At first the initial analyses of tar deposits (elemental, thermogravimetric, and calorimetric analyses) were performed. After the characterization, the tar deposits were extracted in the Soxhlet extractor by acetone, toluene, and quinolone and activated with potassium hydroxide. As the final step of this work, the sorption characterization

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RILEY, C., S. ADEBAYO, A. WHEATLEY, and H. ASEMOTA. "The interplay between yam (Dioscorea sp.) starch botanical source, micromeritics and functionality in paracetamol granules for reconstitution." European Journal of Pharmaceutics and Biopharmaceutics 70, no. 1 (2008): 326–34. http://dx.doi.org/10.1016/j.ejpb.2008.03.001.

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Kaur, Harjeet, Baldeep Kumar, Amitava Chakrabarti, et al. "A New Therapeutic Approach for Brain Delivery of Epigallocatechin Gallate: Development and Characterization Studies." Current Drug Delivery 16, no. 1 (2018): 59–65. http://dx.doi.org/10.2174/1567201815666180926121104.

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Background: Blood-brain permeability is the primary concern when dealing with the biodistribution of drugs to the brain in neurological diseases. Objective: The purpose of the study is to develop the nanoformulation of Epigallocatechin gallate (EGCG) in order to improve its bioavailability and penetration into the brain. Methods: EGCG loaded Solid Lipid Nanoparticles (SLNs) have been developed using microemulsification method and pharmacological assessments were performed. Results: Surface morphology and micromeritics analysis showed the successful development of EGCG loaded solid lipid nanopa

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Rashad, Amira A., Sara Nageeb El-Helaly, Randa T. Abd El Rehim, and Omaima N. El-Gazayerly. "Core-in-cup/liquisol dual tackling effect on azelnidipine buccoadhesive tablet micromeritics, in vitro release, and mucoadhesive strength." Acta Pharmaceutica 69, no. 3 (2019): 381–98. http://dx.doi.org/10.2478/acph-2019-0022.

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Abstract Reduced bioavailability of azelnidipine is related to its poor aqueous solubility and extensive first-pass metabolism, which hinder its efficacy. These problems were addressed by implementing (1) a liquisol technique for promoting the dissolution rate in a controlled-release manner and (2) a core-in-cup bucco-adhesive drug delivery system as an alternative to the oral route. A 33 factorial design was used to study the effects of polymer type (sodium carboxymethyl cellulose (CMC Na), chitosan, or Carbomer P940) concentration (5, 10 or 15 %) and preparation technique (simple mix, liquis

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Amore, Ricardo, Clóvis Pagani, Michel Nicolau Youssef, Camillo Anauate Netto, and Hugo Roberto Lewgoy. "Polymerization shrinkage evaluation of three packable composite resins using a gas pycnometer." Pesquisa Odontológica Brasileira 17, no. 3 (2003): 273–77. http://dx.doi.org/10.1590/s1517-74912003000300013.

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Modern restorative dentistry has been playing an outstanding role lately since composite resins, allied to adhesive systems, have been widely applied on anterior and posterior teeth restorations. The evolution of composite resins has mostly been verified due to the improvement of their aesthetic behavior and the increase in their compressive and abrasive strengths. In spite of these developments, the polymerization shrinkage inherent to the material has been a major deficiency that, so far, has been impossible to avoid. Using a gas pycnometry, this research investigated the polymerization shri

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Goñi, S., and A. Guerrero. "Role of Combined Water for Determining the Mechanical Behaviour of Class C Fly Ash Belite Cements." Materials Science Forum 636-637 (January 2010): 1252–57. http://dx.doi.org/10.4028/www.scientific.net/msf.636-637.1252.

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The physically-chemically bounded water is an important parameter directly related to the gain of mechanical strength during the hydration of cements. In this work, quantitative determinations of the physically - chemically bounded water of two types of belite cements, called FABC-2-W and FABC-2-N, were carried out by means of thermogravimetry analyses during a period of 180 days of hydration. The hydrated products were characterized by X-ray diffraction and BET surface area. Important direct quantitative correlations were obtained between the combined water and technological characteristics o

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Shahgaldi, Samaneh, Zahira Yaakob, Norazrina Mat Jali, Dariush Jafar Khadem, Wan Ramli Wan Daud, and Edy Herianto Majlan. "Influence of Iron Oxide Nano Particles on Electrospun Poly (Vinylidene Fluride)-Based Carbon Nanofibers on Hydrogen Storage." Key Engineering Materials 471-472 (February 2011): 1184–89. http://dx.doi.org/10.4028/www.scientific.net/kem.471-472.1184.

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Electrospun Poly (vinylidene fluoride) (PVdF) fine fiber of 100-300 nm in diameter in ribbon shape was synthesized through the electrospinning process via sol-gel. In order to synthesize infusible nanofibers all processing of dehydrofluorination and carbonization was investigated. Iron nanoparticles was doped with PVDF nanofibers in order to be effective in surface area, and porosity to increase the hydrogen storage. The composition, morphology, structure and surface area of PVDF/Iron Oxide nanofibers were investigated by thermo gravimetric analysis (TGA) to determinate the temperature of poss

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Rodríguez-Dorado, Rosalía, Clara López-Iglesias, Carlos García-González, Giulia Auriemma, Rita Aquino, and Pasquale Del Gaudio. "Design of Aerogels, Cryogels and Xerogels of Alginate: Effect of Molecular Weight, Gelation Conditions and Drying Method on Particles’ Micromeritics." Molecules 24, no. 6 (2019): 1049. http://dx.doi.org/10.3390/molecules24061049.

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Processing and shaping of dried gels are of interest in several fields like alginate aerogel beads used as highly porous and nanostructured particles in biomedical applications. The physicochemical properties of the alginate source, the solvent used in the gelation solution and the gel drying method are key parameters influencing the characteristics of the resulting dried gels. In this work, dried gel beads in the form of xerogels, cryogels or aerogels were prepared from alginates of different molecular weights (120 and 180 kDa) and concentrations (1.25, 1.50, 2.0 and 2.25% (w/v)) using differ

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Nwabor, Ozioma Forstinus, Sudarshan Singh, Dwi Marlina, and Supayang Piyawan Voravuthikunchai. "Chemical characterization, release, and bioactivity of Eucalyptus camaldulensis polyphenols from freeze-dried sodium alginate and sodium carboxymethyl cellulose matrix." Food Quality and Safety 4, no. 4 (2020): 203–12. http://dx.doi.org/10.1093/fqsafe/fyaa016.

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Abstract Crude ethanolic extract of Eucalyptus camaldulensis was encapsulated with sodium alginate–sodium carboxymethyl cellulose (CMC) using freeze-drying techniques. The microcapsules were characterized for particle size, morphology, physicochemical parameters, and micromeritics properties. Antioxidant and antimicrobial activities of the microcapsules were also demonstrated. Results revealed an irregular-shaped microparticles with a mean diameter ranging from 6.7 to 26.6 µm. Zeta potential and polydispersity index ranged from −17.01 to 2.23 mV and 0.34 to 0.49, respectively. Percentage yield

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Auriemma, Giulia, Andrea Cerciello, Rita P. Aquino, Pasquale Del Gaudio, Bruno M. Fusco, and Paola Russo. "Pectin and Zinc Alginate: The Right Inner/Outer Polymer Combination for Core-Shell Drug Delivery Systems." Pharmaceutics 12, no. 2 (2020): 87. http://dx.doi.org/10.3390/pharmaceutics12020087.

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Core-shell beads loaded with betamethasone were developed using co-axial prilling as production technique and pectin plus alginate as polymeric carriers. During this study, many operative conditions were intensively investigated to find the best ones necessary to produce uniform core-shell particle systems in a reproducible way. Particularly, feed solutions’ composition, polymers mass ratios and the effect of the main process parameters on particles production, micromeritics, inner structure, drug loading and drug-release/swelling profiles in simulated biological fluids were studied. The optim

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Zhang, Qian, Bing Lin, Junming Hong, and Chang-Tang Chang. "Removal of ammonium and heavy metals by cost-effective zeolite synthesized from waste quartz sand and calcium fluoride sludge." Water Science and Technology 75, no. 3 (2016): 587–97. http://dx.doi.org/10.2166/wst.2016.508.

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This study focuses on the effectiveness of zeolite (10% CF-Z [0.5]) hydrothermally synthesized from waste quartz sand and calcium fluoride (CF) for ammonium ion and heavy metal removal. Zeolite was characterized through powder X-ray diffraction, Fourier-transform infrared spectroscopy, micromeritics N2 adsorption/desorption analysis, and field emission scanning electron microscopy. The effects of CF addition, Si/Al ratio, initial ammonium concentration, solution pH, and temperature on the adsorption of ammonium on 10% CF-Z (0.5) were further examined. Results showed that 10% CF-Z (0.5) was a s

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Şahbaz, Deniz Akın, and Caglayan Acikgoz. "Cross-linked chitosan/marble powder composites for the adsorption of Dimozol Blue." Water Science and Technology 76, no. 10 (2017): 2776–84. http://dx.doi.org/10.2166/wst.2017.447.

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Abstract Cross-linked chitosan(C)/marble powder (M) composites with different weight ratio percentage (C100M0, C70M30, C50M50, and C30M70) were prepared from marble powder and chitosan and cross-linked using glutaraldehyde. The morphology and the surface area of the chitosan/marble powder composites were also characterized with a scanning electron microscope (SEM) and Micromeritics (ASAP 2020) BET (Brunauer, Emmett and Teller) instrument, respectively. To evaluate the adsorption behaviour of the chitosan/marble powder composites, 0.1 g adsorbent was added into 50 mL Diamozol Blue BRF %150 (C.I

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Migoha, C. O., M. Ratansi, E. Kaale, and G. Kagashe. "Preformulation Studies for Generic Omeprazole Magnesium Enteric Coated Tablets." BioMed Research International 2015 (2015): 1–9. http://dx.doi.org/10.1155/2015/307032.

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Preformulation is an important step in the rational formulation of an active pharmaceutical ingredient (API). Micromeritics properties: bulk density (BD) and tapped density (TD), compressibility index (Carr’s index), Hauser’s ratio (H), and sieve analysis were performed in order to determine the best excipients to be used in the formulation development of omeprazole magnesium enteric coated tablets. Results show that omeprazole magnesium has fair flow and compressibility properties (BD 0.4 g/mL, TD 0.485 g/mL, Carr’s index 17.5%, Hauser’s ratio 1.2, and sieve analysis time 5 minutes). There we

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Colpas, Fredy, Arnulfo Tarón, and Waldyr Fong. "Analisis del desarrollo textural de carbones activados preparados a partir de zuro de maíz." Temas Agrarios 20, no. 1 (2016): 103–12. http://dx.doi.org/10.21897/rta.v20i1.752.

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Algunos residuos agrícolas pueden ser útiles para producir materiales adsorbentes como son los de carbones activados. Tal es el caso del Zuro de maíz, el cual fue utilizado como material de partida en esta investigación, Para la preparación de carbón activado, inicialmente el zuro libre de granos de maíz es carbonizado a temperatura de 400 °C, posteriormente los carbonizados fueron activados químicamente con ácido ortofosfórico, los carbones activados obtenidos fueron modificados con ácido nítrico y peróxido de hidrógeno, previo calentamiento a 600°C para observar su desarrollo textural. Los s

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Tan Peng Jun, Patrick, Wan Nur Aisyah Wan Osman, Shafirah Samsuri, Juniza Md Saad, Muhamad Fadli Samsudin, and Eduard Hernández Yáñez. "Factory Tea Waste Biosorbent for Cu(II) and Zn(II) Removal from Wastewater." E3S Web of Conferences 287 (2021): 04006. http://dx.doi.org/10.1051/e3sconf/202128704006.

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Recent studies have shown great interest toward heavy metal removal due to its hazardous and non-biodegradable properties. Many approaches have been used for this purpose and one of them is adsorption. In this study, several experiments were carried out to investigate the feasibility of factory tea waste as a biosorbent in a fixed-bed adsorption column for heavy metal removal (zinc and copper) in wastewater. The results highlighted that zinc has better performance compared to copper in terms of the effect of initial ion concentration, pH value, and the mixed ions with respect to the removal ef

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Jelvehgari, Mitra, Fatemeh Atapour, and Ali Nokhodchi. "Micromeritics and release behaviours of cellulose acetate butyrate microspheres containing theophylline prepared by emulsion solvent evaporation and emulsion non-solvent addition method." Archives of Pharmacal Research 32, no. 7 (2009): 1019–28. http://dx.doi.org/10.1007/s12272-009-1707-y.

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23

SAIM, S. "Isomerization of 1-Hexene over Pt/$gamma;-Al2O3 catalyst: Reaction mixture density and temperature effects on catalyst effectiveness factor, coke laydown, and catalyst micromeritics." Journal of Catalysis 131, no. 2 (1991): 445–56. http://dx.doi.org/10.1016/0021-9517(91)90278-c.

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Patil, Arun Trambak, Deepak Shamrao Khobragade, Sandip Annaji Chafle, Amol Prasadrao Ujjainkar, Sudhir Niranjanrao Umathe, and Champalal Laxminarayan Lakhotia. "Development and evaluation of a hot-melt coating technique for enteric coating." Brazilian Journal of Pharmaceutical Sciences 48, no. 1 (2012): 69–77. http://dx.doi.org/10.1590/s1984-82502012000100008.

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Conventional enteric coating requires the use of organic based polymers which are equally hazardous to the environment and operating personnel. Hot-melt coating avoids the use of solvents and is a safer and time-saving process. The present study was designed to assess the efficacy of hot-melt coating (HMC) as an enteric coating technique. Pellets prepared by extrusion spheronization were selected as the core formulation for a model of the gastric irritant drug diclofenac sodium (DFS) because of their innate advantages over single-unit formulations. Stearic acid (SA) and palmitic acid (PA) were

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Maurya, Harikesh, and Tirath Kumar. "FORMULATION, STANDARDIZATION, AND EVALUATION OF POLYHERBAL DISPERSIBLE TABLET." International Journal of Applied Pharmaceutics 11, no. 1 (2019): 158. http://dx.doi.org/10.22159/ijap.2019v11i1.30113.

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Objective: The study was designed as formulation, standardization, and evaluation of polyherbal dispersible tablet prepared for the management of kidney disorders. To overcome the problem of dyspepsia in geriatric patients by the use of polyherbal dispersible tablets.Methods: Dispersible tablets were prepared using aqueous root extract powder of the selected plant viz. A. officinalis, B. diffusa, C. papaya, C. fistula, C. intybus, F. hispida, F. indica, C. nurvala, S. virgaurea, and V. negundo with the help of superdisintegrant addition technique using crospovidone, sodium starch glycolate and

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Maghsoodi, Maryam, Seyed hassan Montazam, Hossein Rezvantalab, and Mitra Jelvehgari. "Response Surface Methodology for Optimization of Process Variables of Atorvastatin Suspension Preparation by Microprecipitation Method Using Desirability Function." Pharmaceutical Sciences 26, no. 1 (2020): 61–74. http://dx.doi.org/10.34172/ps.2019.52.

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Background : Atorvastatin (AT), as a synthetic lipid-lowering agent, is a highly crystalline substance having poor solubility and low bioavailability. The objective of the present research was to improve the microprecipitation method of AT suspension preparation. Methods: Microprecipitation parameters were improved using Box-Behnken experimental design method. The suspension was formulated with Brij 35 (stabilizer agent) using methanol as solvent and water as non-solvent, respectively. DSC, XRD, FTIR studies were performed for characterization of the microcrystals. With the aim of evaluating t

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Prashant Singh and Ritu M. Gilgotra. "Formulation and evaluation of guar gum based matrix tableted glibenclamide microspheres." International Journal of Research in Pharmaceutical Sciences 11, no. 2 (2020): 2445–57. http://dx.doi.org/10.26452/ijrps.v11i2.2238.

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The purpose of this investigation is to establish anti-diabetic activity relationship as well as efficiency of formulated guar gum matrix tablet using microencapsulated glibenclamide (GBLD). This research is an approach to utilize pharmaceutical excipients as an alternative hypoglycemic agent. In order to execute the objective, GBLD microspheres were formulated by emulsion solvent evaporation method using dichloromethane and methanol as solvent system which was transferred drop after drop into encapsulating medium i.e. liquid paraffin light. The formulated microspheres were exposed to various

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Dudzińska, Agnieszka, Mieczysław Żyła, and Janusz Cygankiewicz. "Influence of The Metamorphism Grade and Porosity of Hard Coal on Sorption and Desorption of Propane / Wpływ Stopnia Metamorfizmu I Porowatości Węgli Kamiennych Na Sorpcję I Desorpcję Propanu." Archives of Mining Sciences 58, no. 3 (2013): 867–79. http://dx.doi.org/10.2478/amsc-2013-0060.

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Abstract In this paper results of investigations of sorption of hard coal samples collected from the extracted coal seams of Polish coal mines are presented. As sorbate propane was used. Examinations were carried out in the temperature of 298 K by means of volumetric assessment with the use of apparatus ASAP 2010 of Micromeritics. On the basis of conducted examinations it has been found out that the amount of sorbed propane depend on a type of coal, its metamorphism grade, content of oxygen element, moisture and porosity of these coals. The greatest amounts of propane are sorbed by low carboni

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Prasetyo, Joni, Nurdiah Rahmawati, Galuh Wirama Murti, et al. "Preliminary Study Of Local Catalyst For Low Cost Methanol Synthesis As Subsequence Process Of A Model System Of Biomass Fluidized Bed Catalytic Gasification." E3S Web of Conferences 67 (2018): 02035. http://dx.doi.org/10.1051/e3sconf/20186702035.

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Biomass waste has been emerging as an alternative energy and fuel. Direct combustion of biomass leads to harmful substances such as NOx and CO which are environmentally unfriendly manner. Innovation of clean technologies like gasification would have a potential in developing technology to reduce the emissions of harmful substances into the environment. The syngas of biomass gasification is an intermediate product which can be converted further to various types of alternative fuels especially methanol. Agency for the Assessment and application of Technology (BBPT)-Indonesia in cooperation with

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SAIM, S., та B. SUBRAMANIAM. "ChemInform Abstract: Isomerization of 1-Hexene Over Pt/γ-Al2O3 Catalyst: Reaction Mixture Density and Temperature Effects on Catalyst Effectiveness Factor, Coke Laydown, and Catalyst Micromeritics". ChemInform 22, № 52 (2010): no. http://dx.doi.org/10.1002/chin.199152075.

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Zaman, Muhammad, Sadaf Saeed, Rabia Imtiaz Bajwa, et al. "Synthesis and Evaluation of Thiol-Conjugated Poloxamer and Its Pharmaceutical Applications." Pharmaceutics 13, no. 5 (2021): 693. http://dx.doi.org/10.3390/pharmaceutics13050693.

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The current study was designed to convert the poloxamer (PLX) into thiolated poloxamer (TPLX), followed by its physicochemical, biocompatibilities studies, and applications as a pharmaceutical excipient in the development of tacrolimus (TCM)-containing compressed tablets. Thiolation was accomplished by using thiourea as a thiol donor and hydrochloric acid (HCl) as a catalyst in the reaction. Both PLX and TPLX were evaluated for surface morphology based on SEM, the crystalline or amorphous nature of the particles, thiol contents, micromeritics, FTIR, and biocompatibility studies in albino rats.

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Pinto, Joana T., Sarah Zellnitz, Tomaso Guidi, Francesca Schiaretti, Hartmuth Schroettner, and Amrit Paudel. "Spray-Congealing and Wet-Sieving as Alternative Processes for Engineering of Inhalation Carrier Particles: Comparison of Surface Properties, Blending and In Vitro Performance." Pharmaceutical Research 38, no. 6 (2021): 1107–23. http://dx.doi.org/10.1007/s11095-021-03061-5.

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Abstract Purpose Traditionally, α-lactose monohydrate is the carrier of choice in dry powder inhaler (DPI) formulations. Nonetheless, other sugars, such as D-mannitol, have emerged as potential alternatives. Herein, we explored different particle engineering processes to produce D-mannitol carriers for inhaled delivery. Methods Wet-sieving and spray-congealing were employed as innovative techniques to evaluate the impact of engineering on the particle properties of D-mannitol. To that end, the resulting powders were characterized concerning their solid-state, micromeritics and flowability. Aft

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Murdjeva, Mariana A., Emilia T. Milieva, Rumen S. Stefanov, Marian M. Draganov, and Petko B. Krastev. "Experimental Investigations: Micromeritic Procedures In Assessing Antinuclear Antibody Patterns In Immunofluorescent Assay." Folia Medica 56, no. 3 (2014): 182–86. http://dx.doi.org/10.2478/folmed-2014-0026.

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ABSTRACT AIM: The aim of this study was to introduce a micromeritic procedure (a statistical approach for small objects) in indirect immunofluorescence assay (IFA) to fi nd objective quantitative parameters of antinuclear antibody (ANA) patterns which could support a diagnosis of auto-immune diseases. MATERIALS AND METHODS: Sera of patients with systemic autoimmune diseases, McCoy-Plovdiv serum-free cell line, goat anti-human immunoglobulin-G FITC-conjugate, fluorescent microscope, computer-assisted digital image processing, analysis using a micromeritic procedure, ANOVA. RESULTS: Three ANA fl

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Ertan, G., I. Sarigüllü, and T. Guneri. "Micromeritic Properties of Nitrofurantoin Microcapsules." Drug Development and Industrial Pharmacy 21, no. 11 (1995): 1323–28. http://dx.doi.org/10.3109/03639049509063020.

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OZYAZICI, M. "Micromeritic studies on nicardipine hydrochloride microcapsules." International Journal of Pharmaceutics 138, no. 1 (1996): 25–35. http://dx.doi.org/10.1016/0378-5173(96)04516-4.

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Islam, Md Sazzadul, and Md Saiful Islam Pathan. "Improving Micromeritic Properties of Ibuprofen: An Agglomeration Approach." Bangladesh Pharmaceutical Journal 20, no. 1 (2017): 90–98. http://dx.doi.org/10.3329/bpj.v20i1.32098.

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Ibuprofen is one of the common NSAIDs having poor water solubility, low dissolution, weak flow properties and reduced compressibility. These downsides of ibuprofen crystal upraise crucial challenges during development of a dosage form. The aim of this present work was to modify the physical form of ibuprofen by changing micromeritic properties. Seven different formulations of ibuprofen agglomerates such as F-1, F-2, F-3, F-4, F-5, F-6 and F-7 were prepared to convert the needle shaped ibuprofen crystals into agglomerates so that the desired micromeritic properties can be achieved. In this stud

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Saikia, Trideep, Jonab Ali, and Biswajit Das. "ISOLATION AND CHARECTERIZATION OF TAMARIND SEED POLYSACCHARIDES–A NATURAL RELEASE RETARDANT." International Journal of Current Pharmaceutical Research 9, no. 4 (2017): 114. http://dx.doi.org/10.22159/ijcpr.2017v9i4.20972.

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Objective: The main objective was to isolate and characterise a naturally obtain polysaccharides which have the property to formulate sustain release product.Methods: Tamarind Seed Polysaccharides (TSP) was isolated from seed of Tamarindus indica by crushed the seed into powder and boiled with water at 45 °C to extract the polysaccharides. After boiling for 12 h the supernatant liquids were collected and stored in cool place. After the liquids become cooled acetone was added and freeze at-40 °C. Freeze materials then lyophilized to extract out the Tamarind seed polysaccharides. After that poly

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Saritha, Damineni, Penjuri Subhash Chandra Bose, Poreddy Srikanth Reddy, Grandhi Madhuri, and Ravouru Nagaraju. "Improved dissolution and micromeritic properties of naproxen from spherical agglomerates: preparation, in vitro and in vivo characterization." Brazilian Journal of Pharmaceutical Sciences 48, no. 4 (2012): 667–76. http://dx.doi.org/10.1590/s1984-82502012000400010.

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Naproxen, an anti-inflammatory drug, exhibits poor aqueous solubility, which limits the pharmacological effects. The present work was carried out to study the effect of agglomeration on micromeritic properties and dissolution. Naproxen agglomerates were prepared by using a three solvents system composed of acetone (good solvent), water (non-solvent) and dichloromethane (bridging liquid). Differential Scanning Calorimetry (DSC) results showed no change in the drug after crystallization process. X-Ray Powder Diffraction (XRPD) studies showed the sharp peaks are present in the diffractograms of s

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Nikolakakis, I., K. Kachrimanis, and S. Malamataris. "Relations between crystallisation conditions and micromeritic properties of ibuprofen." International Journal of Pharmaceutics 201, no. 1 (2000): 79–88. http://dx.doi.org/10.1016/s0378-5173(00)00398-7.

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Gupta, Venkadari, Srinivas Mutalik, Madhobhai Patel, and Girish Jani. "Spherical crystals of celecoxib to improve solubility, dissolution rate and micromeritic properties." Acta Pharmaceutica 57, no. 2 (2007): 173–84. http://dx.doi.org/10.2478/v10007-007-0014-8.

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Spherical crystals of celecoxib to improve solubility, dissolution rate and micromeritic propertiesCelecoxib spherical agglomerates were prepared with polyvinylpyrrolidone (PVP) using acetone, water and chloroform as solvent, non-solvent and bridging liquid, respectively. The agglomerates were characterized by differential scanning calorimetry (DSC), X-ray diffraction (XRD), IR spectroscopic studies and scanning electron microscopy (SEM). The IR spectroscopy and DSC results indicated the absence of any interactions between drug and additives. XRD studies showed a decrease in crystallinity in a

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Таmarkina, Ju V., I. B. Frolova, O. O. Velichko, and V. O. Кucherenko. "ADSORPTION OF PHENOL COMPOUNDS BY ACTIVATED CARBON FORMED DURING CARBONIZATION OF BROWN COAL WITH POTASSIUM HYDROXIDE." Journal of Coal Chemistry 2 (2021): 21–32. http://dx.doi.org/10.31081/1681-309x-2021-0-2-21-32.

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The aim of the work is to evaluate the adsorption capacity of activated carbons (ACs) from brown coal in relation to phenol (Ph) and 4-chlorophenol (CPh) and the influence of the AСs formation temperature under carbonization with potassium hydroxide on capacities. The samples of ACs were prepared by heating with KOH (1 g/g, 1 h) at a given temperature in the range of t=400-800°C and marked as AC(t). The ACs porosity characteristics were determined by low-temperature (77 K) adsorption – desorption nitrogen isotherms (Micromeritics ASAP 2020) calculated by the 2D-NLDFT method. They are as follow

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Nath, Shelli, and Yashwant V. Pathak. "Evaluation of maltodextrins as tablet excipients I. Micromeritic and compressional characterization." Powder Technology 75, no. 1 (1993): 97–101. http://dx.doi.org/10.1016/0032-5910(93)80029-a.

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Sowa, Michał, Anneke R. Klapwijk, Michael Ostendorf, and Wolfgang Beckmann. "Particle Engineering of an Active Pharmaceutical Ingredient for Improved Micromeritic Properties." Chemical Engineering & Technology 40, no. 7 (2017): 1282–92. http://dx.doi.org/10.1002/ceat.201600663.

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Patil, Ashwini, Yogesh Pore, Yogesh Gavhane, Shitalkumar Patil, and Sachinkumar Patil. "Spherical crystallization of ezetimibe for improvement in physicochemical and micromeritic properties." Journal of Pharmaceutical Investigation 44, no. 3 (2014): 213–24. http://dx.doi.org/10.1007/s40005-014-0117-4.

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Badhana, Seema, Navneet Garud, and Akanksha Garud. "Colon specific drug delivery of mesalamine using eudragit S100-coated chitosan microspheres for the treatment of ulcerative colitis." International Current Pharmaceutical Journal 2, no. 3 (2013): 42–48. http://dx.doi.org/10.3329/icpj.v2i3.13577.

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The purpose of the present study was to prepare, characterize and evaluate the colon-targeted microspheres of mesalamine for the treatment and management of ulcerative colitis (UC). Microspheres were prepared by the ionic-gelation emulsification method using tripolyphosphate (TPP) as cross linking agent. The microspheres were coated with Eudragit S-100 by the solvent evaporation technique to prevent drug release in the stomach. The prepared microspheres were evaluated for surface morphology, entrapment efficiency, drug loading, micromeritic properties and in-vitro drug release. The microsphere

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Manivannan, Subramanian, Akshay M, Bhuvaneswari S, and Nify F. "FORMULATION AND EVALUATION OF GASTRORETENTIVE MICROBALLOONS OF ACEBROPHYLLINE FOR THE TREATMENT OF BRONCHIAL ASTHMA." Asian Journal of Pharmaceutical and Clinical Research 9, no. 5 (2016): 105. http://dx.doi.org/10.22159/ajpcr.2016.v9i5.12603.

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ABSTRACTObjective: Gastroretentive dosage forms are an approach for prolonged and predictable drug delivery in the upper gastrointestinal tract to controlthe gastric residence time. Microballoons are considered as one of the most promising buoyant drug delivery systems as they possess the advantagesof both multiple-unit systems and good floating properties. Acebrophylline is a xanthine derivative with potent bronchodilator, mucosecretolytic, andanti-inflammatory property. It is used to treat bronchial asthma and chronic obstructive pulmonary diseases.Methods: Microballoons of acebrophylline we

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Prabakaran, L., and Meenakshi Bajpai. "Novel Micropelletization Technique: Highly Improved Dissolution, Wettability and Micromeritic Behavior of Domperidone." Current Drug Delivery 3, no. 3 (2006): 307–13. http://dx.doi.org/10.2174/156720106777731046.

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Chime, SalomeA, EC Umeyor, VI Onyishi, GC Onunkwo, and AA Attama. "Analgesic and micromeritic evaluations of SRMS-based oral lipospheres of diclofenac potassium." Indian Journal of Pharmaceutical Sciences 75, no. 3 (2013): 302. http://dx.doi.org/10.4103/0250-474x.117436.

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Zhang, Peiqi, Shanshan Tie, Mengpei Liu, and Wei Zong. "Effects of superfine grinding on micromeritic properties of Eucommia ulmoides Oliv. leaves." Bangladesh Journal of Botany 49, no. 4 (2020): 1037–44. http://dx.doi.org/10.3329/bjb.v49i4.52536.

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Effects of regular grinding and superfine grinding on the micromeritic properties of Eucommia ulmoides leaves were investigated. Coarse powder 1 (5732 nm), 2 (4784.67 nm), 3 (4133.67 nm), 4 (2119 nm) were prepared by regular grinding. Superfine powder 5 (1310.67 nm) was prepared by superfine grinding, all the particle sizes presented normal distribution. Results showed that Eucommia ulmoides leaf powders have smaller size, greater bulk density and smaller angle of repose. The water solubility index values, water holding capacity value and oil binding capacity value were significantly improved

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Gupta, V. Rama Mohan, Srikanth K, Sree Giri Prasad, B, G. Naveen Kumar Reddy, and Sudheer B. "Formulation and Evaluation of Directly Compressible Agglomerates of Celecoxib." International Journal of Pharmaceutical Sciences and Nanotechnology 3, no. 4 (2011): 1193–204. http://dx.doi.org/10.37285/ijpsn.2010.3.4.4.

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Prepared spherical crystals of Celecoxib to increase the compressible properties, dissolution rate and bioavailability, using hydrophilic polymers such as PEG-4000, sod.CMC, sod.alginate and PVP K-30. All the formulations were characterized for micromeritic properties, Drug loading, solubility, in vitro drug release and mean dissolutiom time (MDT). New formulations showed higher dissolution rates and less MDT values than the pure celecoxib. Among all, the crystals prepared with 10 % w/v PVP K-30 exhibited maximum dissolution rate (2.95±0.23%) and very less MDT values (18.50 ± 4.01 min). Hence

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