Relevant bibliographies by topics / Microneedle technology

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  1. Journal articles
  2. Dissertations / Theses
  3. Books
  4. Book chapters
  5. Conference papers

Academic literature on the topic 'Microneedle technology'

Author: Grafiati
Published: 2 June 2025
Last updated: 31 July 2025

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Journal articles on the topic "Microneedle technology"

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Pavan, Khomane Reshma Mirajkar* Ashwini Madgulkar Mrunmayee Velapure. "Microneedle Technology: Advancements, Applications, and Future Different Directions." International Journal of Pharmaceutical Sciences 3, no. 5 (2025): 3412–22. https://doi.org/10.5281/zenodo.15473291.

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Microneedle Technology: Progress, Uses, and Prospects Micro needles, micro meter-sized instruments for minimally invasive transdermal delivery, provide an auspicious option against conventional injections. This review canvasses the new developments in micro needle technology with features of pain-free application, better drug bioavailability, and minimizing bio hazardous waste. We consider here the several different types of microneedles, namely, solid, coated, dissolving, and hydrogel, specifically designed for selected drug delivery strategies and therapeutic indications. The manufacturing p
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Kadam, Snehal Kasu Daniya Momin Ishrat Shaikh Shama* Khan Sharina Poonam Patil. "Microneedle Technology: A Revolutionary Approach to Drug Delivery." International Journal of Pharmaceutical Sciences 3, no. 4 (2025): 106–39. https://doi.org/10.5281/zenodo.15119727.

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Microneedle system is a type of new generation transdermal drug delivery systems (TDDS) which eliminate the main disadvantages of drug administration through the skin. This paper undertakes a review of the development of the microneedle technology which has been developed as a non-invasive procedure in drug delivery across the skin because it reduces the effectiveness of the first barrier to penetration, the stratum corneum. One improved characteristic of microneedles is that they span several wells yet their size makes them permeable to water and small molecule drugs therefore providing more
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Rizwan, Boyeekati Mohammad, Nawaz Mahammed, Shaik Farheen Taj, V. Sivasai Bharath Kumar, and B. Yamuna. "A Review on Puncturing Potential: Microneedles' Present Landscape And Prospective Horizons." Jordan Journal of Pharmaceutical Sciences 18, no. 2 (2025): 566–85. https://doi.org/10.35516/jjps.v18i2.2763.

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Microneedle technology has emerged as a promising approach for drug delivery, vaccination, diagnostics, and cosmetic treatments. This review provides an overview of microneedle technology, covering the various types of microneedles, fabrication techniques, applications, advantages, challenges, safety considerations, clinical translation, and future perspectives. Solid, hollow, dissolving, coated, and hydrogel-forming microneedles are discussed, along with their structures, materials, and fabrication methods. Applications in drug delivery, vaccination, diagnostics, and cosmetic treatments are e
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Alfisha Khan, Pragati Mishra, Deepika Gupta, and Poonam Kumari. "Advances in Transdermal Drug Delivery Systems: From Patches to Microneedles." Journal of Drug Discovery and Health Sciences 1, no. 02 (2024): 105–12. https://doi.org/10.21590/jddhs.01.02.06.

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Microneedle technology has emerged as a groundbreaking innovation in transdermal drug delivery systems (TDDS), offering a less invasive method to administer drugs through the skin. These micron-sized needles penetrate the stratum corneum, the outermost layer of the skin, to deliver therapeutic agents ranging from vaccines to insulin and biologics. The four main types of microneedles—solid, coated, dissolvable, and hollow—each serve unique purposes in optimizing drug delivery efficiency and patient comfort.Solid microneedles are typically made of metals like stainless steel and titanium, offeri
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Nguyen, Hiep X., and Chien N. Nguyen. "Microneedle-Mediated Transdermal Delivery of Biopharmaceuticals." Pharmaceutics 15, no. 1 (2023): 277. http://dx.doi.org/10.3390/pharmaceutics15010277.

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Transdermal delivery provides numerous benefits over conventional routes of administration. However, this strategy is generally limited to a few molecules with specific physicochemical properties (low molecular weight, high potency, and moderate lipophilicity) due to the barrier function of the stratum corneum layer. Researchers have developed several physical enhancement techniques to expand the applications of the transdermal field; among these, microneedle technology has recently emerged as a promising platform to deliver therapeutic agents of any size into and across the skin. Typically, h
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Xu, Jie, Danfeng Xu, Xuan Xuan, and Huacheng He. "Advances of Microneedles in Biomedical Applications." Molecules 26, no. 19 (2021): 5912. http://dx.doi.org/10.3390/molecules26195912.

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A microneedle (MN) is a painless and minimally invasive drug delivery device initially developed in 1976. As microneedle technology evolves, microneedles with different shapes (cone and pyramid) and forms (solid, drug-coated, hollow, dissolvable and hydrogel-based microneedles) have been developed. The main objective of this review is the applications of microneedles in biomedical areas. Firstly, the classifications and manufacturing of microneedle are briefly introduced so that we can learn the advantages and fabrications of different MNs. Secondly, research of microneedles in biomedical ther
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Kang, Seongsu, Ji Eun Song, Seung-Hyun Jun, Sun-Gyoo Park, and Nae-Gyu Kang. "Sugar-Triggered Burst Drug Releasing Poly-Lactic Acid (PLA) Microneedles and Its Fabrication Based on Solvent-Casting Approach." Pharmaceutics 14, no. 9 (2022): 1758. http://dx.doi.org/10.3390/pharmaceutics14091758.

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Microneedles have emerged as a novel transdermal delivery tool that enables the delivery of various products such as drugs, vaccines, or cosmetic ingredients. Although the demand for solid microneedles composed of biocompatible polymer is increasing, the manufacture of microneedles using poly-lactic acid (PLA) with rapid drug-releasing is yet to be established and the process is still in its infancy. Here, we propose a novel strategy for the fabrication of PLA solid microneedles which enable a drug to be burst-released based on a solvent-casting process. This approach offers extreme simplicity
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Choo, Sangmin, SungGiu Jin, and JaeHwan Jung. "Fabricating High-Resolution and High-Dimensional Microneedle Mold through the Resolution Improvement of Stereolithography 3D Printing." Pharmaceutics 14, no. 4 (2022): 766. http://dx.doi.org/10.3390/pharmaceutics14040766.

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Microneedles are transdermal drug delivery tools that can be fabricated simply, economically, and rapidly using SLA 3D printing. However, SLA 3D printing has a limitation in that the resolution is slightly lowered when the microneedle is precisely printed. To solve this issue, we optimized the SLA 3D printing conditions such as printing angle, needle height, aspect ratio, and spacing between the microneedles for high-resolution microneedle fabrication. The sharpest microneedle tip was obtained when the printing angle was adjusted to 60° in both the x and y axes. The aspect ratio and the spacin
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Amato, Camilla, Daria Cermola, Raffaele Vecchione, and Carla Langella. "Design for optimisation of drug administration." Journal of Health Design 9, no. 1 (2024): 605–10. http://dx.doi.org/10.21853/jhd.2024.224.

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In the last few years, a new technology based on microneedles has been used for the delivery of drugs and vaccines. Microneedle patches ensure rapid, easy, and hygienic administration of drugs. This project was conceived to ensure the comfortable and safe transport as well as the sterile application of microneedles by users. Microneedles are particularly useful for diseases requiring daily medical care via distributed therapeutic treatments throughout the day. Microneedle Reminder is a wearable device for the wrist, containing nine ready-to-use patches.
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Gaurav P. Aswar, Pooja R. Hatwar, Ravindra L. Bakal, Vaishnavi S. Kalamb, and Ishar K. Thak. "Microneedles: An efficient technique to enhance Transdermal Drug Delivery System." GSC Biological and Pharmaceutical Sciences 29, no. 3 (2024): 256–66. https://doi.org/10.30574/gscbps.2024.29.3.0480.

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Microneedle technology has emerged as a promising tool for enhancing transdermal drug delivery. This technology involves the use of micron-sized needles to create microchannels in the skin, allowing for the delivery of drugs, vaccines, and other therapeutic agents. The skin's outermost layer, the stratum corneum, is the primary barrier to drug penetration, and microneedles have been shown to effectively bypass this barrier. Various types of microneedles have been developed, including solid, coated, dissolving, and hollow microneedles, each with its own advantages and disadvantages. Microneedle
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Dissertations / Theses on the topic "Microneedle technology"

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Quinn, Helen Louise. "Microneedle technology for older people." Thesis, Queen's University Belfast, 2016. http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.709697.

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It is evident that the global population is ageing, with an increasing proportion of people aged over 65 years. Typically associated with a high proportion of morbidity and mortality, care of the increasing ageing population presents a challenge, with age-appropriate research required to promote and facilitate healthy ageing. In the present work, a novel drug delivery technology, designed to enhance transdermal drug delivery, was considered in the context of its potential future use in the older population. Microneedles (MNs) consist of a plurality of tiny projections in the micron scale, arra
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Roxhed, Niclas. "A Fully Integrated Microneedle-based Transdermal Drug Delivery System." Doctoral thesis, Stockholm : Kungliga Tekniska högskolan, 2007. http://urn.kb.se/resolve?urn=urn:nbn:se:kth:diva-4484.

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Yang, Chieh-Cheng, and 楊傑丞. "Process Parameter Study of Dip-drawing Technology for Making Microneedle Array." Thesis, 2019. http://ndltd.ncl.edu.tw/handle/69ktww.

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碩士<br>國立彰化師範大學<br>機電工程學系<br>107<br>This paper presents a parameter study of the dip-drawing process of making high aspect-ratio polymeric microneedles. The process involves dip-pad spin coating, dip-drawing, UV-curing, necking, and breaking. To gain more insight into the process, we study three major process parameters including curing time, drawing speed, dip-mold’s tip diameter, they are critical parameters of the microneedle fabrication process. We also make different microneedles by setting a series of process parameters through dip-drawing platform. To prepare the experiment, we design an
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Guo, Ming-Sheng, and 郭銘勝. "Study on the microneedle arrays for transdermal drug delivery using wet etch technology." Thesis, 2005. http://ndltd.ncl.edu.tw/handle/25695538350383571465.

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碩士<br>國立臺灣海洋大學<br>輪機工程系<br>93<br>Generally for treatment, it may use the syringes to inject drug but always cause human body to get pain. Therefore there were many successive studies of microneedles for human body to avoid getting pain and also to deliver drug. There is no pain of human body due to microneedle without exciting the end of nerve. The great number of blood capillaries of the human body increases the absorption of medicine. To use the silicon wafer with crystalline grain direction (100) and simple mark, the out-of-plane microneedle arrays with 460 μm in height can be done by the t
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Silvestre, Sara Isabel Laiginha. "Biopolymer based microneedles patch by laser technology for biomedical applications." Master's thesis, 2018. http://hdl.handle.net/10362/50168.

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One of the most important issues in creating new drug delivery methods is improving drug permeation into the skin. Therefore, many techniques have been proposed, such as oral administration, intradermal vaccines, transdermal patches, among others, but all of them present several limitations. In the past few years, a new effective, innovative and safe drug delivery system was proposed. This technology is named as microneedles (MNs) and it is a hybrid combination of hypodermic injections and transdermal drug delivery systems, which consists in micro-scale needles that can pierce the skin by a si
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Guimarães, Tânia Marisa Teixeira. "Alginate-derived microneedle devices for transdermal delivery of rivastigmine - application in skin mimetic model." Master's thesis, 2021. https://hdl.handle.net/10216/137363.

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Pires, Ana Carolina Sebastião. "Laser technology and 3D printing for production of biopolymer-based hollow microneedles patch for biomedical applications." Master's thesis, 2018. http://hdl.handle.net/10362/58231.

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One of the major challenges of transdermal drug delivery is the creation of methods that allow greater bioavailability of drugs. Many techniques have been proposed in order to address this issue such as hypodermic injections and transdermal patches. However, all presented several disadvantages, such as the requirement of administration by trained people and poor bioavailability. Thus, microneedles have emerged as a promising alternative, since they are less invasive and a painless method for delivering drugs through the skin. In this dissertation, a low-cost procedure was proposed, without re
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Rajabi, Mina. "Flexible and Stretchable Biointerfacing for Healthcare Diagnostics." Licentiate thesis, 2019. http://urn.kb.se/resolve?urn=urn:nbn:se:kth:diva-245075.

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Flexible and stretchable wearable biomedical devices provide a platform for continues long-term monitoring of biological signals during neutral body movements thus enabling early intervention and diagnostics of various diseases. This thesis evaluates novel flexible and stretchable bio interfacing medical devices based on microneedle patches and split ring resonator for healthcare diagnostics. Flexible and stretchable microneedle patches were realized by integrating a soft polymer substrate with sharp stainless steel microneedles. This was realized using a magnetic assembly technique. Investiga
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Books on the topic "Microneedle technology"

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Talreja, Neetu, Divya Chauhan, and Mohammad Ashfaq, eds. Microneedles (MNs)-Based Technology. Springer Nature Singapore, 2025. https://doi.org/10.1007/978-981-96-3916-8.

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Book chapters on the topic "Microneedle technology"

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Quinn, Helen L., Aaron J. Courtenay, Mary-Carmel Kearney, and Ryan F. Donnelly. "Microneedle Technology." In Novel Delivery Systems for Transdermal and Intradermal Drug Delivery. John Wiley & Sons, Ltd, 2015. http://dx.doi.org/10.1002/9781118734506.ch9.

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Jusoh, Mazura, Nurul Asmak Md Lazim, and Zaki Yamani Zakaria. "Microneedle-Based Technology for Agriculture and Safety." In Series in BioEngineering. Springer Nature Singapore, 2025. https://doi.org/10.1007/978-981-96-3916-8_15.

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Teixeira, Miguel Lima, Camilo Velez, Dian Li, and João Goes. "Microneedle Based ECG – Glucose Painless MEMS Sensor with Analog Front End for Portable Devices." In IFIP Advances in Information and Communication Technology. Springer International Publishing, 2017. http://dx.doi.org/10.1007/978-3-319-56077-9_45.

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Moffatt, Kurtis, and Ryan F. Donnelly. "Microneedle technology." In Drug Delivery Devices and Therapeutic Systems. Elsevier, 2021. http://dx.doi.org/10.1016/b978-0-12-819838-4.00004-3.

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"Microneedle Systems for Vaccine Delivery." In Encyclopedia of Pharmaceutical Science and Technology, Fourth Edition. CRC Press, 2013. http://dx.doi.org/10.1081/e-ept4-120050304.

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"Applications of Microneedle Technology to Transdermal Drug Delivery." In Toxicology of the Skin. CRC Press, 2010. http://dx.doi.org/10.3109/9781420079180-22.

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Hutton, Aaron R. J., Yu Wu, Ke Peng, Thakur Raghu Raj Singh, and Ryan F. Donnelly. "Microneedle Approaches to Ocular Drug Delivery." In Ophthalmic Biomaterials. Royal Society of Chemistry, 2025. https://doi.org/10.1039/9781839169779-00399.

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Conventional ocular drug therapies (e.g. eye drops, ointments and solutions) have long been associated with high patient compliance as they can be self-administered with minimal discomfort. However, it is often difficult to achieve therapeutic effects with topical treatments due to the presence of lacrimal fluid and the barrier properties of the cornea. Consequently, direct injection into the posterior segments of the eye using a hypodermic needle is typically employed. Not only does this require the expertise of a trained healthcare professional, but highly invasive methods can cause signific
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Supe, Akshay R., Abhishek Nemmaniwar, Gargi Dhaneshwar, Riya Singh, and Neetu A. Khatri. "EMERGING ERA OF MICRONEEDLE TECHNOLOGY FOR TRANSDERMAL DRUG DELIVERY SYSTEM." In Futuristic Trends in Pharmacy & Nursing Volume 3 Book 17. Iterative International Publishers, Selfypage Developers Pvt Ltd, 2024. http://dx.doi.org/10.58532/v3bkpn17p2ch5.

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The skin is an important organ that protects the body from harmful effects including massive water damage and synthetic chemical attacks. The primary skin barrier, the stratum corneum, which is a component of the epidermis, is made up of 15-20 corneocyte layers.3-5 Transdermal medication delivery offers an important alternative to oral and hypodermic injections. There are three layers to human skin: the hypodermis, dermis, and epidermis. It might solve the problem of drug degradation and liver or gastrointestinal absorption. It is non-invasive, painless, and self-administered. Microarray patch
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Prausnitz, Mark, Harvinder Gill, and Jung-Hwan Park. "Microneedles for Drug Delivery." In Modified-Release Drug Delivery Technology, Second Edition. CRC Press, 2008. http://dx.doi.org/10.3109/9781420045260-23.

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Kaushik, Diksha, Brian Kilfoyle, Rashmi Thakur, and Bozena B. Michniak-Kohn. "Microneedles – Minimally Invasive Transdermal Delivery Technology." In Handbook of Non-Invasive Drug Delivery Systems. Elsevier, 2010. http://dx.doi.org/10.1016/b978-0-8155-2025-2.10006-x.

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Conference papers on the topic "Microneedle technology"

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Tran, Khoa-Dang. "Towards Non-Invasive Continuous Glucose Monitoring: A Study on Minimally Invasive Enzymatic Microneedle Biosensors." In 2024 7th International Conference on Green Technology and Sustainable Development (GTSD). IEEE, 2024. http://dx.doi.org/10.1109/gtsd62346.2024.10675222.

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Huang, Zhe, Yanran Wang, Junshi Li та ін. "Intracortical Flexible Microneedle Neural Electrode (f-μNeurode) Based on Projection-Micro-Stereolithography (PμSL) Technology for Chronic In-Vivo Electrophysiological Recording". У 2025 IEEE 38th International Conference on Micro Electro Mechanical Systems (MEMS). IEEE, 2025. https://doi.org/10.1109/mems61431.2025.10917939.

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Haider, Kazim, Thomas Lijnse, Lisa van de Panne, Catherine Betancourt Lee, Alec Lamb, and Colin Dalton. "Wire bonded solid metal microneedles: a versatile platform technology for transdermal drug delivery and biosensing." In Microfluidics, BioMEMS, and Medical Microsystems XXIII, edited by Bastian E. Rapp and Colin Dalton. SPIE, 2025. https://doi.org/10.1117/12.3040404.

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Chen, Yaoxin, and Yuan Cong. "Domestic technology review of microneedle patents." In International Conference on Modern Medicine and Global Health (ICMMGH 2023), edited by Sheiladevi Sukumaran. SPIE, 2023. http://dx.doi.org/10.1117/12.3000296.

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Novakovic, Katarina, E. Hutchinson, Wing Man Lau, T. Abdelghany, and Keng Wooi Ng. "CHITOSAN HYDROGEL BASED MICRONEEDLE TECHNOLOGY FOR PROLONGED RELEASE OF ACTIVES." In 17th International Conference on Fundamental and Applied Aspects of Physical Chemistry. Society of Physical Chemists of Serbia, 2024. https://doi.org/10.46793/phys.chem24i.139n.

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Microneedle patches, with needles of sub-millimeter size, are non-invasive and pain free way of drug delivery. The needles penetrate skin, pass stratum corneum, but do not penetrate tissue which contains nerves and blood vessels. In this work, a new and unique chitosan-hydrogel based composite material was formulated to produce microneedle patches and their potency for extended drug delivery was validated using methylene blue as a model drug.
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An, Eunjin, Hong Kee Kim, Jung Dong Kim, et al. "Cutaneous Drug Delivery System: Characteristics of Drug Loaded Dissolving Microneedle Technology." In The 3rd World Congress on Recent Advances in Nanotechnology. Avestia Publishing, 2018. http://dx.doi.org/10.11159/nddte18.113.

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Garcia, Jennifer, Ismael Rios, and Faruk Fonthal. "Structural and microfluidic analysis of microneedle array for drug delivery." In 2016 31st Symposium on Microelectronics Technology and Devices (SBMicro). IEEE, 2016. http://dx.doi.org/10.1109/sbmicro.2016.7731332.

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Kim, Jung Dong, Jung-hyun Bae, Hong Kee Kim, and Do Hyeon Jeong. "Droplet-born Air Blowing(DAB) Technology for the Industrialization of Dissolving Microneedle." In The World Congress on Recent Advances in Nanotechnology. Avestia Publishing, 2016. http://dx.doi.org/10.11159/nddte16.122.

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Widianto, Davira P., Benjamin G. Stewart, Juan L. Mena-Lapaix, et al. "Microneedle Insertion into Visco-Hyperelastic Model for Skin for Healthcare Application." In 2021 IEEE 71st Electronic Components and Technology Conference (ECTC). IEEE, 2021. http://dx.doi.org/10.1109/ectc32696.2021.00236.

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Hasanpour, Feria, and Szilvia Berkó. "3D printing microneedle patch as drug delivery system on the skin." In V. Symposium of Young Researchers on Pharmaceutical Technology,Biotechnology and Regulatory Science. Institute of Pharmaceutical Technology and Regulatory Affairs, University of Szeged, Faculty of Pharmacy, 2023. http://dx.doi.org/10.14232/syrptbrs.2023.67.

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