Academic literature on the topic 'Microparticulate dosage'

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Journal articles on the topic "Microparticulate dosage"

1

Kokate, Shekhar, and Punit R. Rachh. "Microparticulate hot melt pallets technology: a review." Journal of Drug Delivery and Therapeutics 8, no. 6-s (2018): 377–83. http://dx.doi.org/10.22270/jddt.v8i6-s.2131.

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Recent advances in novel drug delivery (NDDS) aims to enhance safety and efficacy of drug molecule by formulating a convenient dosage form for ease of administration and to achieve better patient compliance. Depending upon functionality, it is possible to design different dosages forms which fulfill the therapeutic needs of the patient with improved bioavailability of poorly water soluble drugs, taste masking and preparation of oral dispersible tablets, MUPS and multiple unit formulations. The hot-melt technology is one of the most commonly used method, is devoid of solvent use, solvent dispos
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Chikukwa, Mellisa T. R., Roderick B. Walker, and Sandile M. M. Khamanga. "Formulation and Characterisation of a Combination Captopril and Hydrochlorothiazide Microparticulate Dosage Form." Pharmaceutics 12, no. 8 (2020): 712. http://dx.doi.org/10.3390/pharmaceutics12080712.

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Cardiovascular diseases such as hypertension and cardiac failure in South African children and adolescents are effectively managed long term, using a combination treatment of captopril and hydrochlorothiazide. The majority of commercially available pharmaceutical products are designed for adult patients and require extemporaneous manipulation, prior to administration to paediatric patients. There is a need to develop an age appropriate microparticulate dosing technology that is easy to swallow, dose and alter doses whilst overcoming the pharmacokinetic challenges of short half-life and biphasi
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3

Fathima, A., B. N. Vedha Hari, and D. Ramya Devi. "Development of Microparticulate Sustained Release Dosage Form of Emtricitabine: An Anti-HIV Drug." Asian Journal of Chemistry 26, no. 9 (2014): 2604–10. http://dx.doi.org/10.14233/ajchem.2014.15757.

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4

Sah, Shiv Kumar, Mrs Vasia, Rajkumar Prasad Yadav, Sunny Patel, and Mukesh Sharma. "Microsphere Overview." Asian Journal of Pharmaceutical Research and Development 9, no. 4 (2021): 132–40. http://dx.doi.org/10.22270/ajprd.v9i4.1003.

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The aim of developing continuous or managed delivery mechanisms has always been to minimise dosage duration, resulting in improved patient compliance and less side effects. Microspheres have been shown to minimise dosage, side effects, administration frequency, and the risk of dose dumping. As a result, patient compliance has improved.Targeted drug delivery mechanisms aim for a specific location in the body to maximise drug concentration in a specific tissue or organ, thus improving the drug's therapeutic effectiveness. Microspheres have promised targeted or managed drug distribution in the bo
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Lukova, Paolina, Plamen Katsarov, and Bissera Pilicheva. "Application of Starch, Cellulose, and Their Derivatives in the Development of Microparticle Drug-Delivery Systems." Polymers 15, no. 17 (2023): 3615. http://dx.doi.org/10.3390/polym15173615.

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Micro- and nanotechnologies have been intensively studied in recent years as novel platforms for targeting and controlling the delivery of various pharmaceutical substances. Microparticulate drug delivery systems for oral, parenteral, or topical administration are multiple unit formulations, considered as powerful therapeutic tools for the treatment of various diseases, providing sustained drug release, enhanced drug stability, and precise dosing and directing the active substance to specific sites in the organism. The properties of these pharmaceutical formulations are highly dependent on the
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Gupta, Manish Kumar, Deepak Prakash, and Brahmeshwar Mishra. "Biodegradable microparticulate drug delivery system of diltiazem HCl." Brazilian Journal of Pharmaceutical Sciences 48, no. 4 (2012): 699–709. http://dx.doi.org/10.1590/s1984-82502012000400014.

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The efficacy of a drug in a specific application requires the maintenance of appropriate drug blood level concentration during a prolonged period of time. Controlled release delivery is available for many routes of administration and offers many advantages (as microparticles and nanoparticles) over immediate release delivery. These advantages include reduced dosing frequency, better therapeutic control, fewer side effects, and, consequently, these dosage forms are well accepted by patients. Advances in polymer material science, particle engineering design, manufacture, and nanotechnology have
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Shah, Pervaiz Akhtar, Sajid Bashir, Muhammad Ahsan, Nasir Abbas, Muhammad Zubair Malik, and Hafiz Muhammad Irfan Nazar. "Bioequivalence evaluation of new microparticulate capsule and marketed tablet dosage forms of lornoxicam in healthy volunteers." Tropical Journal of Pharmaceutical Research 15, no. 4 (2016): 877. http://dx.doi.org/10.4314/tjpr.v15i4.30.

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8

Kumar, Tarun, Rimpy Pahwa, and Munish Ahuja. "Grewia asiatica linn. root extract loaded suspension, microparticulate and nanosuspension dosage form: fabrication, characterization and anthelmintic evaluation." ACTA Pharmaceutica Sciencia 60, no. 4 (2022): 363. http://dx.doi.org/10.23893/1307-2080.aps6024.

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9

Svedberg, Anna, and Tom Lindström. "A pilot web former designed to study retention-formation relationships." Nordic Pulp & Paper Research Journal 25, no. 2 (2010): 185–94. http://dx.doi.org/10.3183/npprj-2010-25-02-p185-194.

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Abstract A pilot-scale fourdrinier former has been developed for the purpose of investigating the relationship between retention and paper formation (features, retention aids, dosage points, etc.). The main objective of this publication was to present the R-F (Retention and formation)-machine and demonstrate some of its fields of applications. For a fine paper stock (90% hardwood and 10% softwood) with addition of 25% filler (based on total solids content), the relationship between retention and formation was investigated for a microparticulate retention aid (cationic polyacrylamide together w
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10

Ghosh, Amitava, and Prithviraj Chakraborty. "Formulation and Mathematical Optimization of Controlled Release Calcium Alginate Micro Pellets of Frusemide." BioMed Research International 2013 (2013): 1–14. http://dx.doi.org/10.1155/2013/819674.

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Objective. Frusemide loaded calcium alginate micropellets, an oral microparticulate delivery system, was statistically optimized exhibiting prolonged therapeutic action minimizing its adverse effects.Methods. Ionotropic Gelation technique was adopted employing 32Factorial designs and keeping the entire process free from organic solvents. Physicochemical and the release characteristics of the prepared formulations were studied, keeping variations only in sodium alginate (primary polymer) and Acrycoat E30D (copolymer) dispersion.Result. Sodium alginate was predominant over Acrycoat E30D in all b
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